ライフサイエンスコーパス: prolonged exposure

1 g and implementing the aftereffect following prolonged exposure.

2 epress myometrial contractility is lost with prolonged exposure.

3 uvancy may be transient or require higher or prolonged exposure.

4 wer attrition and higher response rates than prolonged exposure.

5 epression may fare better with IPT than with prolonged exposure.

6 (a difference <12.5 points in CAPS score) to prolonged exposure.

7 forced by glucocorticoid, and continued with prolonged exposure.

8 Castleman's disease and well tolerated with prolonged exposure.

9 ough reductions in photoreceptor levels upon prolonged exposure.

10 apoptosis was observed at lower [DIDS] with prolonged exposure.

11 PTSD, with some evidence of an advantage for prolonged exposure.

12 versible at a high NO concentration or after prolonged exposure.

13 in a virtual reality environment, even after prolonged exposure.

14 domly assigned to 10 weeks of treatment with prolonged exposure (10 sessions) plus paroxetine (N=19)

15 clock transcriptional oscillations, whereas prolonged exposure (10 weeks) to LL disrupts islet circa

16 nce of disgusting images habituate following prolonged exposure.(7)(,)(8) Under normal physiological

17 ANOG, SOX2) remained unaffected, until after prolonged exposure (96 hrs).

18 CPT and prolonged exposure also outperformed waitlist and treatm

19 ed a randomized 14-week trial comparing IPT, prolonged exposure (an exposure-based exemplar), and rel

20 receptor (GLP-1R) potency and in obtaining a prolonged exposure and action of the GLP-1 analogue.

21 indicate a well-developed 'reef stage' with prolonged exposure and colonization of the bones prior t

22 exposure, dermal absorption of BPA leads to prolonged exposure and may lead to higher proportions of

23 ated in combination with pazopanib, allowing prolonged exposure and promising durable responses in pa

24 Prolonged exposure and sertraline confer significant ben

25 ference on the differential effectiveness of prolonged exposure and sertraline for the treatment of p

26 Using intent-to-treat analyses (N=200), both prolonged exposure and sertraline showed large gains tha

27 After week 10, patients discontinued prolonged exposure and were offered 12 additional weeks

28 30% in CAPS score, were 63% for IPT, 47% for prolonged exposure, and 38% for relaxation therapy (not

29 Further study of repeated exposure, prolonged exposure, and vulnerable subgroups is needed.

30 ent to 70% of participants receiving CPT and prolonged exposure attained clinically meaningful sympto

31 the incidence of these tumors plateaus with prolonged exposure, but the incidence of other skin canc

32 However, prolonged exposures can exacerbate respiratory failure.

33 During treatment, participants receiving prolonged exposure demonstrated greater improvement on t

34 ion along the intracellular route and, under prolonged exposure, desensitization.

35 CAPS outcomes for IPT and prolonged exposure differed by 5.5 points (not significa

36 We observed that prolonged exposure due to FcRn-mediated enhancement of h

37 nd in the cell number was observed after the prolonged exposure except for 5.0 g/L nZVI at which bact

38 sessment was used to identify compounds with prolonged exposure following oral dosing.

39 Prolonged exposure for 7 days lowered the concentration

40 er to achieve acceptable bioavailability and prolonged exposures for once-daily dosing, good colonic

41 A random subset of the prolonged exposure group (N=17) underwent single-pulse t

42 y, thymidine was restricted to patients with prolonged exposure (> 96 hours) to methotrexate (MTX) or

43 st-line trauma-focused interventions CPT and prolonged exposure have shown clinically meaningful impr

44 pies, cognitive processing therapy (CPT) and prolonged exposure, have been the most frequently studie

45 IPT and prolonged exposure improved quality of life and social f

46 ts the DNA-binding signature of ERalpha upon prolonged exposure in breast cancer.

47 m in human liver microsomes and which showed prolonged exposure in mice.

48 ose) through these composite coatings during prolonged exposure in PBS.

49 Capacity to benefit from prolonged exposure in PTSD is gated by the degree to whi

50 r agents, paclitaxel also displayed a unique prolonged exposure in sciatic nerve and DRG.

51 tion is the capacity of the amended AC after prolonged exposure in the field.

52 The intervention consisted of modified prolonged exposure including imaginal exposure to the tr

53 nselective cation channel; while repeated or prolonged exposure induces formation of a transmembrane

54 erol) or synthetic agonists acutely or after prolonged exposure induces insulin hypersecretion.

55 These findings suggest that the modified prolonged exposure intervention initiated within hours o

56 modified peptide counterpart; however, after prolonged exposure it also caused liposome lysis.

57 evels can build up in the body tissues after prolonged exposure leading to undesired effects.

58 ysfunction and loss of neuronal integrity on prolonged exposure of Abeta in cells transfected with al

59 Prolonged exposure of adenocarcinoma xenografts to andro

60 The authors have demonstrated that prolonged exposure of adult rabbit extraocular muscle (E

61 Prolonged exposure of beta-cells to cytokines or thapsig

62 Sharma and colleagues demonstrated that prolonged exposure of cancer cells to TKIs give rise to

63 Prolonged exposure of cartilage surfaces to stick-slip s

64 Prolonged exposure of CD8(+) T cells to antigenic stimul

65 ant (CPA) chemicals and the damage caused by prolonged exposure of cells to these high concentrations

66 Here we provide evidence that prolonged exposure of cultured human airway smooth muscl

67 Prolonged exposure of cultures to 2.5 microM TMRM produc

68 We conclude that prolonged exposure of ECs to rapamycin increases p27(Kip

69 A(2A)ARs in regulating STAT protein levels, prolonged exposure of endogenous A(2A)ARs in endothelial

70 Prolonged exposure of hippocampal neurons to antibodies

71 Prolonged exposure of human gastric epithelial cells and

72 We found that prolonged exposure of human macrophages to TNF resulted

73 Prolonged exposure of human subcutaneous fibroblast cult

74 Prolonged exposure of islets to high concentrations of I

75 halation with improved anti-cancer efficacy, prolonged exposure of lung-resident tumors to the antine

76 Prolonged exposure of mice to diet containing 0.1% 3,5-d

77 Here we found that prolonged exposure of naive wild-type mice to EE signifi

78 Prolonged exposure of NRVMs to LUF7244 or LUF7244 plus a

79 who may not respond to eculizumab will avoid prolonged exposure of such individuals to the infectious

80 s neutralization, supports the proposal that prolonged exposure of the bNAb epitope enabled the matur

81 ower and incomplete viral escape resulted in prolonged exposure of the bNAb epitope, which may in tur

82 al factors such as stressful experiences and prolonged exposure of the brain to addictive drugs promo

83 dest and required both prolonged fasting and prolonged exposure of the brain to insulin, raising doub

84 nance of chronic anxiety and pain induced by prolonged exposure of the CeA to CORT.

85 cerevisiae Grx5 purified aerobically, after prolonged exposure of the cell-free extract to air or af

86 Prolonged exposure of the central amygdala (CeA) to elev

87 e of enhanced susceptibility to MPER mAbs is prolonged exposure of the MPER neutralizing epitope duri

88 st likely as a result of the higher and more prolonged exposure of the sulfone derivative.

89 Here, we report that prolonged exposure of TRPV1 to agonists induces rapid re

90 Prolonged exposure of trypanosomes to AEE788 inhibited t

91 ssigned to no choice were then randomized to prolonged exposure or sertraline.

92 is possible that changes in the brain due to prolonged exposure or to the progression of dependence l

93 Patients preferred prolonged exposure over sertraline (number needed to ben

94 severity, there was a significant benefit of prolonged exposure over sertraline on interview-rated lo

95 Prolonged exposure (PE) therapy has been shown to be hig

96 Patients treated with prolonged exposure plus paroxetine experienced significa

97 sure (10 sessions) plus paroxetine (N=19) or prolonged exposure plus placebo (N=18).

98 prolonged exposure was more efficacious than prolonged exposure plus placebo for PTSD related to the

99 erapy (a CBT) plus paroxetine (an SSRI) with prolonged exposure plus placebo in the treatment of terr

100 ombined treatment than patients treated with prolonged exposure plus placebo.

101 wever, mean posttreatment scores for CPT and prolonged exposure remained at or above clinical criteri

102 lex I, reducing cardiac-cell beat rate, with prolonged exposure resulting in cell death.

103 tely two-thirds of patients receiving CPT or prolonged exposure retained their PTSD diagnosis after t

104 However, higher concentrations of H2O2, or prolonged exposure, reversed these changes and led to an

105 On prolonged exposure, Semapimod causes accumulation of TLR

106 T (that included 481 patients) and 4 RCTs of prolonged exposure (that included 402 patients) met incl

107 The authors compared prolonged exposure therapy (a CBT) plus paroxetine (an S

108 ceived fourteen 60- to 90-minute sessions of prolonged exposure therapy (n = 31) or supportive counse

109 rticipated in a randomized clinical trial of prolonged exposure therapy (n = 36) versus treatment wai

110 ors assessed changes in brain function after prolonged exposure therapy across three emotional reacti

111 Combined treatment medication and prolonged exposure therapy deserves further study in lar

112 In addition, there is a concern that prolonged exposure therapy for PTSD may exacerbate alcoh

113 We examined whether augmentation of prolonged exposure therapy for PTSD with DCS enhances tr

114 debilitating anxiety disorder, and, although prolonged exposure therapy has been proven effective, ma

115 Participants were randomly assigned to (1) prolonged exposure therapy plus naltrexone (100 mg/d), (

116 However, those in the prolonged exposure therapy plus naltrexone group had the

117 hange, -63.9% [95% CI, -73.6% to -54.2%] for prolonged exposure therapy plus naltrexone; -63.9% [95%

118 sure therapy plus naltrexone (100 mg/d), (2) prolonged exposure therapy plus pill placebo, (3) suppor

119 exone; -63.9% [95% CI, -73.9% to -53.8%] for prolonged exposure therapy plus placebo; -69.9% [95% CI,

120 Counselors previously naive to prolonged exposure therapy provided the treatments in a

121 elated PTSD experienced greater benefit from prolonged exposure therapy than from supportive counseli

122 Prolonged exposure therapy was composed of 12 weekly 90-

123 Prolonged exposure therapy was not associated with an ex

124 toms in all 4 groups, but the main effect of prolonged exposure therapy was not statistically signifi

125 Extinction of fear memories through prolonged exposure therapy, the primary evidence-based b

126 ly than nondepressed patients to drop out of prolonged exposure therapy.

127 ituximab suggest that increased doses and/or prolonged exposure times can improve the outcome of elde

128 uld be simultaneously transformed to ethene, prolonged exposure to 1,2-dichloroethane diminished the

129 nsformed into K(2)(H(2)O)(4)B(12)F(12) after prolonged exposure to 21 Torr H(2)O((g)) at 25 degrees C

130 During prolonged exposure to a given motosensory gain, persiste

131 This study explores effects of prolonged exposure to a high cholesterol high fat (HCHF)

132 fect of DNA demethylation was transient, and prolonged exposure to a methylation inhibitor induced di

133 utralizing titers in response to intense and prolonged exposure to a primary measles case patient.

134 We combined visual adaptation, in which the prolonged exposure to a specific visual feature alters p

135 Our data show that prolonged exposure to a-syn oligomers, but not monomers

136 n and interaction of signaling pathways upon prolonged exposure to Abeta in model nerve cells express

137 ptors has been widely studied, the impact of prolonged exposure to Abeta on nAChR expression and sign

138 ells lacking this enzyme might be subject to prolonged exposure to adenosine, which has immunosuppres

139 After an immediate contraction, prolonged exposure to ADP causes BSM to become refractor

140 Collectively, prolonged exposure to AGEs in the liver promotes an AGER

141 During prolonged exposure to Ags, such as chronic viral infecti

142 ed to date is achieved and maintained during prolonged exposure to air.

143 Prolonged exposure to alcohol, tobacco, and pathogenic a

144 In spite of prolonged exposure to ambient oxidizing conditions, ~49%

145 Prolonged exposure to an atherogenic diet decreases LTL

146 Prolonged exposure to an AWC sensed odor in the absence

147 Here, we show that prolonged exposure to an enriched environment (EE) facil

148 cinated individuals following intense and/or prolonged exposure to an infected individual and may pre

149 malignant cells following 24-hour treatment, prolonged exposure to androgen was required to detect th

150 at Ang II acutely increases ENaC Po, whereas prolonged exposure to Ang II also induces translocation

151 permits a small fraction of cells to survive prolonged exposure to antibiotics.

152 organisms persist in ocular tissues despite prolonged exposure to antifungal agents.

153 ss in treating hallucinations and delusions, prolonged exposure to antipsychotic medications leads to

154 Furthermore, prolonged exposure to BQCA markedly extended the lifespa

155 We conclude that prolonged exposure to broad spectrum antibiotics in the

156 Interestingly, prolonged exposure to catalytic inactive thrombin incuba

157 -nephrin(+) EVs ratio and may be mediated by prolonged exposure to cellfree HbF.

158 rise from abnormal responses of the brain to prolonged exposure to challenging environmental stimuli.

159 can develop multidrug resistance (MDR) after prolonged exposure to chemotherapeutic drugs, which is a

160 rated a reduction in VMAT2 binding following prolonged exposure to cocaine.

161 However, prolonged exposure to cognate antigens often attenuates

162 These mechanistic insights support using prolonged exposure to cognitive novelty and/or oral beta

163 The impact of other risk factors, including prolonged exposure to combined antiretroviral therapy (c

164 Melatonin therapy or prolonged exposure to complete darkness reduces biliary

165 to progeny virion production, we found that prolonged exposure to COPI complex disruption through si

166 In rats, escalation occurs following prolonged exposure to cycles of alcohol intoxication, an

167 Prolonged exposure to diet-induced euglycemia improves r

168 Prolonged exposure to drugs of abuse, such as cannabinoi

169 ral feature of addictions or are a result of prolonged exposure to drugs of abuse.

170 Upon prolonged exposure to DT, cells with an abnormal morphol

171 Increased concentration of or prolonged exposure to Dyn A is neurotoxic and these dele

172 Intriguingly, prolonged exposure to either PF299804 or WZ4002 results

173 to thermoregulate spermatogenetic tissue and prolonged exposure to elevated temperatures are linked t

174 Prolonged exposure to environmental chemicals (ECs) can

175 ary dysfunction, which may be exacerbated by prolonged exposure to environmental hypoxia.

176 After prolonged exposure to estradiol, P. aeruginosa adopted e

177 Given that prolonged exposure to estrogen and increased telomerase

178 We show that prolonged exposure to ethanol can promote an upregulatio

179 Analysis shows that prolonged exposure to ethyl acetate and several related

180 Adults with prolonged exposure to even moderate elevations in non-hi

181 Prolonged exposure to everolimus significantly improved

182 Prolonged exposure to excess hormone leads to progressiv

183 With prolonged exposure to extreme high altitude (>5500 m), m

184 As a consequence, prolonged exposure to FF depletes intracellular ATP, act

185 Importantly, prolonged exposure to FGF19, but not M70, led to the for

186 A prolonged exposure to finer particles can thus cause adv

187 Here, we have measured the effect of prolonged exposure to GABA or the combination of GABA an

188 n exerts in healthy mammals and discuss that prolonged exposure to ghrelin has been linked to maladap

189 Prolonged exposure to H2 O2 (200 mum, 60 min) induced ap

190 structure and gas sorption properties after prolonged exposure to heat and humidity.

191 on with Gram-negative bacterial pathogens or prolonged exposure to heat-killed Salmonella enterica, t

192 The impact of this prolonged exposure to high Ag loads on the functionality

193 mission occurs is increasing in particularly prolonged exposure to high concentrations in a relativel

194 Under prolonged exposure to high glucose conditions, alms1-def

195 In addition, prolonged exposure to high glucose further increases IL-

196 air defect was mimicked in cultured cells by prolonged exposure to high glucose.

197 whether thermophilic endospores can survive prolonged exposure to high temperatures, sediments were

198 Prolonged exposure to high-efficacy agonists results in

199 inert, while the optogenetic systems require prolonged exposure to high-intensity light.

200 abdominal aorta risk scores, as a result of prolonged exposure to HIV and antiretroviral therapy.

201 rogram at the PD-1 locus becomes fixed after prolonged exposure to HIV virus.

202 ized material were fully retained even after prolonged exposure to hot liquid water.

203 Using prolonged exposure to house dust mite in mice, we develo

204 Prolonged exposure to hyperoxia has deleterious effects

205 and PG production of porcine IVD cells under prolonged exposure to hypoxia with physiological glucose

206 Prolonged exposure to IDELA increased the incidence of a

207 these defects could be overcome by early or prolonged exposure to IL-2, or by addition of IL-12 to c

208 sence of IFN-gamma (Th1 inflammation) or the prolonged exposure to IL-4 (chronic Th2 inflammation) pr

209 ions, the effects on and mechanisms by which prolonged exposure to IL-6 alters HuMC numbers and funct

210 Initial EMT was induced by prolonged exposure to IL6, a cytokine also generated by

211 In more severe GVHD, prolonged exposure to immunosuppressive therapies, failu

212 In contrast, prolonged exposure to junk-food resulted in cross-sensit

213 ouse compared with the wild type mouse after prolonged exposure to kainate.

214 High doses or prolonged exposure to ketamine increase neuronal apoptos

215 atment with nucleos(t)ide analogues, despite prolonged exposure to large loads of antigen.

216 hildren failed to adjust their intake during prolonged exposure to larger portions challenges the sug

217 sible in order to avoid damage to cells from prolonged exposure to laser radiation.

218 ion, especially for health care workers with prolonged exposure to LHR plume.

219 However, it remains unclear whether prolonged exposure to low barometric pressures exacerbat

220 red responses to certain stresses, including prolonged exposure to low temperatures.

221 Prolonged exposure to lower LDL-C beginning early in lif

222 xposure to LPS drives macrophage activation, prolonged exposure to LPS triggers tolerance to LPS, whe

223 nge and is achieved by monocytic cells after prolonged exposure to LPS.

224 ing and phenotypic changes we observed after prolonged exposure to lumican.

225 Our results suggest that prolonged exposure to MEK or ERK inhibitors may not only

226 These metabolic adaptations to prolonged exposure to mild cold may lead to improved glu

227 Research on prolonged exposure to MJ and comprehensive risk characte

228 Only after prolonged exposure to more extreme water stress did acti

229 During prolonged exposure to morphine (two hours), action poten

230 these findings provide direct evidence that prolonged exposure to morphine induces homeostatic plast

231 Likewise, colonic inflammation related to prolonged exposure to morphine was significantly attenua

232 A static stimulus can seem to move after prolonged exposure to movement (the motion aftereffect),

233 Strikingly, prolonged exposure to mutant IDH1 results in irreversibl

234 of neuronal population activity showed that prolonged exposure to nicotine limited cholinergic signa

235 representation in auditory cortex, and that prolonged exposure to noise is necessary to produce this

236 eatures remained fully functional even after prolonged exposure to nonpolar solvents (20 min).

237 Overoxidation by prolonged exposure to O(2) or contact with H(2)O(2) or N

238 Prolonged exposure to opioids results in analgesic toler

239 in wt but not betaarr-2 ko LC neurons after prolonged exposure to opioids.

240 s important to consider the possibility that prolonged exposure to other sensory stimuli will reveal

241 To investigate whether prolonged exposure to overweight during adult life incre

242 uctase NQO1, a detoxifying enzyme induced by prolonged exposure to oxidative stress.

243 Lower air temperature and prolonged exposure to oxygen resulted in greater degrada

244 ydrogen oxidation activity to both brief and prolonged exposure to oxygen.

245 We gave monkeys prolonged exposure to pairs of images presented in fixed

246 chronic illusion of self-motion triggered by prolonged exposure to passive motion, such as from sea o

247 tance mechanism in MET-amplified cells after prolonged exposure to PF2341066.

248 hosphatase, is required for viability during prolonged exposure to pheromone and acts through multipl

249 Prolonged exposure to phosphate is associated with endot

250 Prolonged exposure to polystyrene microplastics signific

251 We hypothesized that prolonged exposure to pro-oxidants in vehicle emissions

252 We observed that prolonged exposure to pro-oxidants in vehicle exhaust in

253 es likely contribute to viral clearance, but prolonged exposure to proinflammatory cytokines released

254 fficient autophagy for cytoprotection, while prolonged exposure to propofol induced cell apoptosis vi

255 sters do not sinter or deactivate even after prolonged exposure to reactants at high temperature, and

256 studies for the ORR demonstrated that after prolonged exposure to reaction conditions, the Pt-bimeta

257 of-the-art platinum-carbon catalysts) during prolonged exposure to reaction conditions.

258 e combination of reduced nephron numbers and prolonged exposure to renal compensatory mechanisms (i.e

259 Each subject showed prolonged exposure to rFVIIIFc relative to rFVIII.

260 rotects sensory neurons and their axons from prolonged exposure to ROS.

261 Prolonged exposure to some antiretroviral drugs might in

262 derstand and predict device service time for prolonged exposure to space environment.

263 Prolonged exposure to spaceflight had little impact on s

264 Prolonged exposure to stress leads to the activation of

265 However, they degrade under prolonged exposure to sunlight.

266 ined a new severity category (level IV) with prolonged exposure to supplemental O2 (>=120 days) that

267 Finally, we observed that prolonged exposure to supraphysiological glucose concent

268 es were less pronounced, probably because of prolonged exposure to TDB found with lower-affinity CD3

269 ter discontinuation of TDF therapy, and more-prolonged exposure to TDF were associated with an increa

270 , the OKR was found to be predictive after a prolonged exposure to temporally periodic visual motion.

271 However, prolonged exposure to TF results in the reduction in PTE

272 rolled, or LCMV CL-13, which leads to a more prolonged exposure to the boosting antigen.

273 ing and is defined as the process by which a prolonged exposure to the cold of winter results in comp

274 was only observed in select cell lines after prolonged exposure to the drug combination and was caspa

275 A double strand breaks being generated after prolonged exposure to the drug.

276 pounds, this shift occurred spontaneously on prolonged exposure to the Lewis acidic reaction conditio

277 However, prolonged exposure to the neurotransmitter drives the re

278 However, prolonged exposure to the SASP causes a subsequent cell-

279 After prolonged exposure to the selective and potent CDK4/6 in

280 zole prophylaxis, there was no evidence that prolonged exposure to this antibiotic has a concurrent e

281 nt tritium had become incorporated following prolonged exposure to tritiated water vapor (HTO) or tri

282 logical and neurobiological complications of prolonged exposure to vehicle emissions remain unknown.

283 alizing antibodies during infection requires prolonged exposure to viral variants.

284 e to temperatures warmer than T(c), and that prolonged exposure to warmer temperatures alters express

285 Prolonged exposure to weak (~1 muT) extremely-low-freque

286 Prolonged exposure to winter cold enables flowering in m

287 pression of which is known to be silenced by prolonged exposure to winter-like temperatures [1].

288 d preterm infants receive frequent and often prolonged exposures to antibiotics because they are vuln

289 Thus, prolonged exposures to IH mimicking sleep apnea are asso

290 play a role in respiratory plasticity after prolonged exposures to low oxygen.

291 als were then randomly assigned to immediate prolonged exposure treatment (N=36) or a waiting list co

292 nts were then randomly assigned to immediate prolonged exposure treatment (N=36) or a waiting list co

293 Neither prolonged exposure (up to 120 h) nor consideration of su

294 Initial treatment with paroxetine plus prolonged exposure was more efficacious than prolonged e

295 Consistent with more recent/prolonged exposure, we found, however, stronger ex vivo

296 With prolonged exposure, we recorded additional responses in

297 group posttreatment effect sizes for CPT and prolonged exposure were large (Cohen d range, 0.78-1.10)

298 CPT and prolonged exposure were marginally superior compared wit

299 ial transmigration with Aspergillus required prolonged exposure with live resting conidia.

300 f the nanofibrils in rats results in greatly prolonged exposure, with a constant oxyntomodulin bioact