ライフサイエンスコーパス: promoter activity

1 g single-cell assays (immunofluorescence and promoter-activity).

2 aB, leading to the down-regulation of LINE-1 promoter activity.

3 ly member Eos, was sufficient to induce Bcl6 promoter activity.

4 rosiglitazone decreased activator protein 1 promoter activity.

5 h TNF-alpha and LPS to induce CXCL1-proximal promoter activity.

6 quired CSRP2BP for robust smooth muscle gene promoter activity.

7 s at -1018 and -57 bp) exhibited the highest promoter activity.

8 cing activity despite the lack of endogenous promoter activity.

9 eb promoter are important to Notch-dependent promoter activity.

10 expression, and promoted NF-kappaB dependent promoter activity.

11 binding and Nurr1, controlling synapsin gene promoter activity.

12 e ability of MKRN3 to repress KISS1 and TAC3 promoter activity.

13 element, TA-box, in the promoter and induced promoter activity.

14 heir functional antagonism in regulating PGF promoter activity.

15 is a critical component for induction of LTR promoter activity.

16 n cardiac myocytes, which increased catalase promoter activity.

17 ia and astrocytes exhibit detectable C9orf72 promoter activity.

18 ker tolbutamide also stimulated primiR-199a2 promoter activity.

19 ) pathway and promoted Sp1 to suppress EphA4 promoter activity.

20 molecules and regulates their expression and promoter activity.

21 tiate RNA synthesis, and enhancers stimulate promoter activity.

22 rachromosomal interactions with synchronized promoter activity.

23 tate receptor-dependent enhancement of COX-2 promoter activity.

24 MEP50 suppresses hINV mRNA level and promoter activity.

25 r mouse lines are based exclusively on c-fos promoter activity.

26 osed for DksA in the regulation of the pArgX promoter activity.

27 increased basal IL-6 mRNA level and greater promoter activity.

28 e efficacy of LBH-589 in augmenting sGCbeta1 promoter activity.

29 riptomes are complex and formed by extensive promoter activity.

30 n of both myocardin- and Notch1-induced MLCK promoter activity.

31 how transcription factor binding impacts on promoter activity.

32 -543 is required for regulation of the mouse promoter activity.

33 Tug1 binds with the TBE to enhance Ppargc1a promoter activity.

34 P1 inhibits HIV-1 long terminal repeat (LTR) promoter activity.

35 m or genetic disruption of REV-ERB increased promoter activity.

36 ation of this domain reduced iron-induced C3 promoter activity.

37 xpression of integrin beta4 by targeting its promoter activity.

38 leolin binding aptamer greatly increased LTR promoter activity.

39 at-mediated HIV-1 LTR (long terminal repeat) promoter activity.

40 e of binding to TCF/LEF increased BACE1 gene promoter activity.

41 we determined the impact of STAT6 on muc5ac promoter activity.

42 ons of the HNF-1beta binding sites abolished promoter activity.

43 in differentiating IECs and stimulated CLDN7 promoter activity.

44 r expressing MKP-3 inhibited the arginase II promoter activity.

45 tes completely blocked the effect of iron on promoter activity.

46 through chromatin looping and affect MAP3K1 promoter activity.

47 s8064454 are associated with decreased HNF1B promoter activity.

48 d that HDAC3 expression markedly reduces Il2 promoter activity.

49 Pro1 region were found to inhibit or enhance promoter activity.

50 at beta-catenin binds to and suppresses Bmp4 promoter activity.

51 c processing causing the increase in TCF/LEF promoter activity.

52 LMW-FGF-2 and HMW-FGF-23 to stimulate FGF-23 promoter activity.

53 4 promoter, and the risk allele reduced NTN4 promoter activity.

54 ective reduction of IkappaBzeta reduces Lcn2 promoter activity.

55 7% of the known common SNPs, on enhancer and promoter activity.

56 to stimulate productive infection and IEtu1 promoter activity.

57 hat were important for dexamethasone induced promoter activity.

58 eased CAV1, CAV2, and CAV3 transcription and promoter activity.

59 d 11 and SIRTs 4 and 6, repress KSHV ori-Lyt promoter activity.

60 inds to the INS and represses cAMP-dependent promoter activity.

61 ions of HIV(+) astrocytes based on the viral promoter activity.

62 consequences of this partnership on Myogenin promoter activity.

63 -6 decreased CAV2 and CAV3 transcription and promoter activity.

64 ed with many motifs are important drivers of promoter activity.

65 ation with heme significantly increased pilA promoter activity.

66 he promoter was critical for GNA13-dependent promoter activity.

67 ts the greatest inhibitory effect on ori-Lyt promoter activity.

68 e levels, thus indirectly increasing Class I promoter activity.

69 gion is important for the regulation of CAT2 promoter activity.

70 d in an intronic site that modulates GUCY1A3 promoter activity.

71 sequences typically encode both enhancer and promoter activities.

72 pause sites led to a significant increase in promoter activities.

73 Rather than contributing positively to promoter activity, a putative initiator element at the t

74 Although the GR had little effect on ICP0 promoter activity alone, the Kruppel-like transcription

75 ide pull-down assays, revealed increased HAB promoter activity-an effect that was prevented by dexame

76 iber cells, as revealed by transcriptome and promoter activity analyses, resulting in shorter fibers

77 ot alter the hyperosmotic status of proximal promoter activities and transcription of key TonEBP targ

78 posure to salt led to a repression of PIP2;7 promoter activity and a significant decrease in PIP2;7 m

79 in more profound reduction of nonrisk allele promoter activity and a significant reduction of endogen

80 l epithelial cells, while also reducing MGMT promoter activity and abolishing MGMT induction.

81 eal a clear correlation between CpG density, promoter activity and accumulation of active or repressi

82 demonstrating that CNV is regulated by both promoter activity and acetylation of histone H3 lysine 5

83 s unspliced NAT down-regulates the main LEF1 promoter activity and attenuates LEF1 mRNA transcription

84 her, ACK1 promoted calcium flux and NFAT-AP1 promoter activity and decreased the motility of murine C

85 Moreover, increased Myc promoter activity and elevated Myc mRNA in AGO1-depleted

86 icator of hypertrophy, and both porcine MYH4-promoter activity and endogenous Myh4 mRNA were also sig

87 RhoA-independent mutant, suppresses Myogenin promoter activity and expression.

88 cle cells revealed a bimodal pattern of MLCK promoter activity and gene expression upon stimulation w

89 ions and siHRT2 treatments that rescued MLCK promoter activity and gene expression.

90 T cell-intrinsic tmTNF/TNFR2 stimulates Il2 promoter activity and Il2 mRNA stability.

91 s been previously found to increase the IL1B promoter activity and is the most frequent haplotype in

92 the impact of -181A-->G polymorphism on MMP7 promoter activity and its association with gastric cance

93 knockdown of Camta1 reduced miR-212/miR-132 promoter activity and miR-212/miR-132 expression, even u

94 21(Cip1) gene promoter to suppress p21(Cip1) promoter activity and mRNA and protein level.

95 Activation of P2Y2R increased TF promoter activity and mRNA expression in HCAEC.

96 CSK9 mRNA and protein, with no effect on its promoter activity and mRNA stability.

97 Y1, 2) overexpression of YY1 decreased EAAT1 promoter activity and mRNA/protein levels, and 3) knockd

98 els, and 3) knockdown of YY1 increased EAAT1 promoter activity and mRNA/protein levels.

99 nally with RUNX2, activating tissue-specific promoter activity and prompting odontoblast differentiat

100 e novo expression of Peg3 increased Beclin 1 promoter activity and protein expression.

101 DNA binding sites are necessary for miR-150 promoter activity and that KLF2 or KLF4 overexpression i

102 We also show that TEAD can inhibit DeltaNp63 promoter activity and that TAZ can directly interact wit

103 ion of the cAMP responsive element abolished promoter activity and the binding of CREB, confirming th

104 Among these targets, NOTCH1 represses ERBB3 promoter activity and the expression of ERBB3.

105 We observed similar effects on TRPC6 promoter activity and TRPC6-dependent calcium influx.

106 STAT3 binding to the TWIST1 promoter, TWIST1 promoter activity and TWIST1 expression, reverts EMT and

107 We analyzed MIR122 promoter activity and validated its target mRNAs by tran

108 -ERB synthetic agonists to inhibit HIV-1 LTR promoter activity and viral replication, supporting a ro

109 mRNA expression, STAT3 phosphorylation, IL-6 promoter activity, and PPAR-delta mRNA and protein expre

110 region, the mutation of which increased ULK1 promoter activity, and rendered it unresponsive to mTOR

111 Taken together, SM-MLCK promoter activity appears highly sensitive to the relati

112 ated TNF-alpha-mediated NF-kappaB luciferase promoter activity as a result of lowered inhibitory Ikap

113 e of multiple repressors with SigB-dependent promoter activity as well as post-transcriptional mechan

114 ieving the partition enhances proximal Zdbf2 promoter activity, as observed during differentiation or

115 By performing a promoter activity assay and DNA binding assays, we firml

116 Using luciferase promoter activity assay combined with site-directed muta

117 vivo ubiquitination assay, chase assay, and promoter activity assay to reach the conclusion.

118 By performing promoter activity assays and chromatin immunoprecipitati

119 By loss- and gain-of-function studies and promoter activity assays, we found that Jagged1/Notch1 s

120 s and measuring their expression to indicate promoter activities at single-mRNA level.

121 if density provides redundancy and increases promoter activity at the expense of tissue specificity,

122 ity serves as a robust mechanism to increase promoter activity at the expense of tissue specificity.

123 plotype was determined in vitro and combined promoter activity based on both alleles (CRPA) was assig

124 We could attribute the differences in Mtor promoter activity between the two mouse strains to a C -

125 tivator CREBBP, and we measured enhancer and promoter activities both before and after neuronal activ

126 Importantly, factor connectivity and promoter activity both associate with perturbation size.

127 ntaining alternative haplotypes and assessed promoter activity both in vitro and in vivo using a luci

128 am binding of RNA polymerase affects the fis promoter activity both in vivo and in vitro.

129 GR and KLF15 cooperate to stimulate bICP0 E promoter activity but significantly less than GR and KLF

130 FN reinforced Nrf2/DNA binding and increased promoter activities by enhancing expression and facilita

131 egulator of Ano1 expression, IL-4, increased promoter activity by 1.6 +/- 0.02-fold over untreated ce

132 4.7 nM) stabilized HIF-1alpha, activated HIF promoter activity by 2.5-fold, and induced HIF-target ge

133 oter was required for the induction of Smad7 promoter activity by KLF4.

134 ve manner, which restores otherwise inactive promoter activity by shortening the length of promoter n

135 0 in vitro, as well as the repression of AFP promoter activity by ZBTB20.

136 ven higher, because we show that dormant LTR promoter activity can rescue loss of an essential upstre

137 slows down due to nutrient limitation, rhlAB promoter activity can stop abruptly, decrease gradually

138 Consistent with their alternative promoter activity, CGI-initiated transcripts are associa

139 f 5' UTR of the waaQ mRNA induces the rpoEP3 promoter activity concomitant with a decrease in LPS con

140 y, mimicking this increase reduces the Kcna2 promoter activity, diminishes Kcna2 expression, decrease

141 Most surprisingly, promoter activity does not require either the forward or

142 veractivation of LytR led to increased lrgAB promoter activity during planktonic and biofilm growth a

143 to the TRPC6 promoter, which inhibits TRPC6 promoter activity, expression, and activity.

144 use podocytes, JAK2 knockdown decreased TFEB promoter activity, expression, and nuclear localization.

145 s quantification of transcription factor and promoter activity, followed by stochastic theoretical an

146 ays demonstrated significantly lower GUCY1A3 promoter activity for constructs carrying this allele.

147 an inference scheme, we can reverse engineer promoter activity from the bioluminescence.

148 ibody, and flow cytometry to quantify GLP-1R promoter activity, gene expression, and protein expressi

149 ulation of Elk1 or Elk1 binding alters ITGB6 promoter activity, gene transcription, and alphavbeta6 i

150 nome coverage, allowing us to map autonomous promoter activity genome-wide in K562 cells.

151 ion, while dynamic DNA methylation modulated promoter activity, illustrating the necessity and suffic

152 CXCR5 locus that negatively regulates CXCR5 promoter activities in a Bach2-dependent manner.

153 moter haplotypes that displayed differential promoter activities in neuronal cells; specifically, hap

154 Our data showed that VDR-enhances Claudin-2 promoter activity in a Cdx1 binding site-dependent manne

155 omoter reporter assay showed reduced HLA-DRA promoter activity in a dose-dependent manner.

156 s a model, we show that ModH5 modulates flaA promoter activity in a GACC methylation-dependent manner

157 ion factors, cooperated to stimulate bICP0 E promoter activity in a ligand-independent manner in mous

158 (0.22 < IC50 < 4.80 muM), down-regulate KRAS promoter activity in a luciferase reporter assay, and re

159 I1.a and BnaC07.ABI1.b in B. napus and their promoter activity in A. thaliana showed differences in t

160 ion of OGA and correspondingly decreased OGA promoter activity in affected cells.

161 screen viral proteins for AP-1 and NF-kappaB promoter activity in AP-1- and NF-kappaB-luciferase repo

162 hared by FOXE1 and PTCSC2, MYH9 inhibits the promoter activity in both directions.

163 n and found REV-ERB agonists inhibited HIV-1 promoter activity in cell lines, primary human CD4 T cel

164 MIR172C-D::GUS showed restricted promoter activity in galls/GCs that was regulated by aux

165 assays, all three variants increased CXCL4L1 promoter activity in HEK293 cells stimulated with IL-1 a

166 rexpression of Wnt6 increases Bdnf and Igf-1 promoter activity in HEK293T cells in a dose-dependent m

167 airs PPARalpha-, ChREBP-, and CREBH-mediated promoter activity in Hepa-1 cells.

168 The VNTR genotype predicts promoter activity in luciferase assays, as well as DNA m

169 Moreover, E. coli increases CD39 promoter activity in macrophages.

170 ells, and that Pro1 fragments display strong promoter activity in mature NK cell and T cell lines as

171 K1/2 pathway to repress PARK2 expression and promoter activity in melanoma cells.

172 blockade by nifedipine reduced primiR-199a2 promoter activity in MIN6 cells, and diazoxide-mediated

173 of RORalpha in COS-1 cells activated CYP2B6 promoter activity in reporter assays.

174 are required for maximal induction of PLPP3 promoter activity in reporter assays.

175 C/EBPbeta elements suppressed the increased promoter activity in response to activated macrophages,

176 al AP-1 site all significantly suppressed TF promoter activity in response to P2Y2R activation.

177 Bioluminescence based on Saa3 promoter activity in Saa3-luc mice was promoted in obese

178 tant RXRA, demonstrating it induces enhancer/promoter activity in the context of RXRA/PPAR heterodime

179 ce confirmed increased Cldn14 expression and promoter activity in the TAL of Ksp-cre;Pth1r(fl/fl) mic

180 (KLF15) cooperated with the GR to stimulate promoter activity in transfected cells.

181 GR or KLF15 alone had little effect on ICP0 promoter activity in transfected Neuro-2A or Vero cells.

182 d basal and HNF3- and glucocorticoid-induced promoter activity in transiently transfected liver and k

183 effects on transcription factor binding and promoter activity in vitro and gene expression in PBMCs

184 However, the strength of promoter activity in vitro does not correlate well with

185 changes in transcription factor binding and promoter activity in vitro.

186 d high-fidelity detection of endogenous Ins2 promoter activity in vivo, and the negative activity in

187 ibitor suberoylanilide hydroxamic acid, WIF1 promoter activity increased significantly while the over

188 eals that when nutrients are abundant, rhlAB promoter activity increases gradually in a density depen

189 RUNX2 overexpression enhanced MMP13 promoter activity, independent of the MMP13 promoter met

190 was unable to increase PTH-stimulated Mmp13 promoter activity, indicating a role for the AP-1 site i

191 rRNA promoters strongly increased intrinsic promoter activity, indicating that R. sphaeroides RNAP c

192 nmt transfection significantly decreases P16 promoter activity, induces complete methylation of P16 C

193 ed to tumorigenic cells, suggesting that LTR promoter activity is dependent upon the transcriptional

194 We observe that maximum promoter activity is determined by TF concentration and

195 Specifically, we show that C9orf72 promoter activity is enriched in corticospinal and spina

196 In the absence of inducer, promoter activity is fully repressed; addition of induce

197 ell with Ly49 expression in vivo and forward promoter activity is generally weak or undetectable, sug

198 are associated with NPC risk; as well as the promoter activity is mediated by functional PIN1 variant

199 cAMP induction of SP-A promoter activity is mediated by increased phosphorylati

200 d in obese adipose tissue, showing that Saa3 promoter activity is most likely related to macrophage i

201 ether with ppGpp a severe down-regulation of promoter activity is observed.

202 Furthermore, we show that gsn promoter activity is rhythmic and is directly controlled

203 lines demonstrated that both StBEL11 and -29 promoter activity is robust in leaf veins, petioles, ste

204 lines demonstrated that both StBEL11 and -29 promoter activity is robust in leaf veins, petioles, ste

205 We demonstrate that C9orf72 promoter activity is widespread in both excitatory and i

206 t a gross level, the distribution of C9orf72 promoter activity largely follows overall cellular densi

207 REST relieved Mn-induced repression of TH promoter activity, mRNA, and protein levels and also red

208 cing of ZSCAN21 increased significantly SNCA promoter activity, mRNA, and protein levels in such cult

209 lytic genes and overexpression decreased the promoter activities of LANA-regulated genes.

210 which might be the reason for the different promoter activities of the HAP and LAP varieties.

211 We measured the enhancer and promoter activities of thousands of DNA fragments transd

212 thermore, PsnSHN2 activated or repressed the promoter activities of transcription factors involved in

213 Here, the promoter activity of all 17 Arabidopsis TET genes was in

214 ecent experiments have shown a heterogeneous promoter activity of autoinducer synthase genes, suggest

215 erase reporter assay shows a decrease in the promoter activity of both rat and mouse genes by Pparalp

216 versus duplex DNA selectivity and suppresses promoter activity of c-MYC gene that contains G-quadrupl

217 evealed that FOXP3 downregulates NFAT-driven promoter activity of CD40L and IL-17.

218 The REV-ERB agonist SR9009 inhibited promoter activity of diverse HIV-subtypes and HIV-1 repl

219 in IECs led to significant reductions in the promoter activity of DRA and its expression.

220 ignificant decrease in p-Akt/AP4 and protein-promoter activity of Gal-1 and fibronectin.

221 gnificant decrease in protein expression and promoter activity of Gal-1.

222 Surprisingly, the greater promoter activity of gene promoters is not due to conven

223 RING finger domain, in order to repress the promoter activity of genes encoding kisspeptin and neuro

224 Consistent with the higher in vitro CHGA promoter activity of haplotype 2, individuals carrying t

225 mic arcuate nucleus and that MKRN3 repressed promoter activity of human KISS1 and TAC3, 2 key stimula

226 vators of NF-kappaB (TNF and LPS), increased promoter activity of MIR122.

227 is the first demonstration and detection of promoter activity of ORF-less GCs from Treponema bacteri

228 In this study, the promoter activity of ORF-less GCs, previously recovered

229 systematically analyzed the distribution of promoter activity of the mouse ortholog of C9orf72 in th

230 the in vitro methylation of CpGs reduced the promoter activity of the MTHFR regulatory region.

231 We tracked the endogenous promoter activity of the neuronal activity-regulated gen

232 However, the bidirectional promoter activity of this element may disturb expression

233 ntaining the intron conversion had increased promoter activity on transient transfection in H295R cel

234 GE) time series datasets to directly measure promoter activities over time.

235 Tfp expression was estimated by pilA promoter activity, pilA gene expression, and relative ab

236 s Hamp gene expression and increase the Hamp promoter activity primarily via three regulatory sequenc

237 SRA inhibits ATGL promoter activity, primarily by inhibiting the otherwise

238 tly regulated promoters, we demonstrate that promoter activity provides a more accurate predictor of

239 Unmethylated THOR repressed TERT promoter activity regardless of TPM status, and hypermet

240 ver, whether this stems from endogenous Ins2 promoter activity remains controversial.

241 ase or increase in Kr-h1 mRNA levels and its promoter activity, respectively.

242 The relative promoter activity (RPA) of each haplotype was determined

243 ese mutations were previously shown to alter promoter activity so that both replication and transcrip

244 hat high miR-375 expression reduced vimentin promoter activity, suggesting that vimentin is an indire

245 However, gene promoters generate more promoter activity than distal enhancers, despite generat

246 Because other SVAs exhibit intrinsic promoter activity that depends in part on the hexameric

247 r escape, helping to offset the reduction in promoter activity that would result from the weak intera

248 2a is a histone acetyltransferase central to promoter activity, that we recently associated with stab

249 , SHP inhibited Npas2 gene transcription and promoter activity through interaction with Rorgamma to r

250 oximal FGF-23 promoter and stimulated FGF-23 promoter activity through PLCgamma/calcineurin/NFAT and

251 organ-specific gene regulation by modulating promoter activity through targeted mutagenesis.

252 oding transcription, we compared genome-wide promoter activity throughout embryogenesis in 5 Drosophi

253 with intrinsic reporting of spatio-temporal promoter activity to generate 18 well-characterised homo

254 ngs suggest that ACTL6A suppresses p21(Cip1) promoter activity to reduce p21(Cip1) protein as a mecha

255 gh glucose dose-dependently increased ADAM17 promoter activity, transcript, and protein levels.

256 In addition, DNA methylation reduced CYP11B1 promoter activity using a reporter assay.

257 studies and human erythroleukemia cells and promoter activity using luciferase reporter studies.

258 The predicted promoter activity values using Promoter 2.0 program is h

259 ANKL promoter SNP that conferred an elevated promoter activity via binding to a transcription factor

260 showed that the two adipokines raised PCSK9 promoter activity via the involvement of a sterol regula

261 High-level nor promoter activity was also detectable in a cell subpopul

262 fs, the contribution of each element to CAT2 promoter activity was analyzed by site directed mutagene

263 ANO1 promoter activity was determined using a luciferase repo

264 ere cloned into reporter constructs, and the promoter activity was determined.

265 After carrageenan, GRB10 promoter activity was enhanced because of activation by

266 n MIN6 cells also revealed that primiR-199a2 promoter activity was enhanced by glucose and reduced by

267 Arginase II promoter activity was increased by approximately 4-fold

268 CYP2C8 promoter activity was increased by ectopic expression of

269 putative response elements to NF-kappaB, and promoter activity was inhibited by p65/p50.

270 DRA promoter activity was measured in a luciferase reporter

271 ITPR2 promoter activity was measured in Huh7 and HepG2 cells.

272 o both alleles in vitro, but decreased HLA-C promoter activity was observed in a luciferase reporter

273 OsNLA1 promoter activity was observed in roots, ligules, leaves

274 on different promoters, as well as the same promoter activity was oppositely regulated by two differ

275 Consistent with these observations, KChIP2 promoter activity was reduced by p65 as well as beta-AR

276 Furthermore, the promoter activity was reduced considerably by in vitro m

277 Constitutive promoter activity was reduced in neurons transfected wit

278 Furthermore, DRA promoter activity was significantly increased in respons

279 milarly, the FSK-mediated induction of Fgf21 promoter activity was strikingly ablated by silencing of

280 PIF3 promoter activity was strongly reduced under -DIF but co

281 this gene for allantoin accumulation, AtALN promoter activity was studied using a reporter system.

282 Arginase II promoter activity was unaffected by a p38 inhibitor or J

283 A20 promoter activity was up-regulated after transfection of

284 l sorting and selection according to insulin promoter activity, we generated a subpopulation(s) of th

285 gh promoter sequence divergence might impact promoter activity, we observed no clear link between the

286 TBA and TBAL transcripts and promoter activities were detected in developing seed coa

287 RhoA GTP binding and promoter activity were increased by Rgnef in combination

288 -repressors of YY1 to further decrease EAAT1 promoter activity, whereas inhibition of HDACs reversed

289 ntrinsically biased toward the generation of promoter activity, whereas others are not.

290 Overexpression of NRF-1 increased TDP1-promoter activity, whereas the introduction of dominant-

291 Accordingly, the promoter activity, which could phenocopy changes in Habp

292 noRNA expression by affecting U3 snoRNA gene promoter activity, while BMP7 was able to increase its e

293 RAS mutant increased LPS-induced arginase II promoter activity, while transfection with a vector expr

294 cell downwardly tunes CRP-dependent Class II promoter activity, whilst elevating CRP steady state lev

295 p A, but not B or C, is able to modulate MYC promoter activity with a significant and dose-dependent

296 h hydrogen peroxide directly inhibited mmp-3 promoter activity with concomitant nuclear translocation

297 Hap -6A/-217A has increased promoter activity with enhanced transcription factor bin

298 This system allows visualization of specific promoter activity with great sensitivity.

299 antly and differentially down-regulated Mtor promoter activity, with MZF1 overexpression reducing Mto

300 We confirmed observable directional promoter activity within the 5'TR element of PB but foun