ライフサイエンスコーパス: promotor

1 s then protonated/metalated by the catalyst (promotor).

2 n/Tcf-4-responsive elements in the PPARdelta promotor.

3 ase pair (bp)/-349-bp region of the proximal promotor.

4 and either the red or the green pigment gene promotor.

5 ed gene transcription from a LEF-1-dependent promotor.

6 i BL21 with the pel gene under the strong T7 promotor.

7 the major histocompatibility complex I gene promotor.

8 t located at position -265/-239 in the EGF-R promotor.

9 full-length HLA-DR4 cDNA driven by a CMV IE promotor.

10 rt of an operon but transcribed from its own promotor.

11 murine leukemia virus long terminal repeat) promotor.

12 cal E-box element located within the alphaBC promotor.

13 nly for infection treatment but also as mass promotor.

14 tor, as the most effective neurite outgrowth promotor.

15 n mouse (Gal3+/+) using a-myosin heavy chain promotor.

16 e dilithium salt of (S)-BINOL was added as a promotor.

17 s driven by the muscle creatine kinase (MCK) promotor.

18 ssociated oncogene 1 and 2, bind to the PLK2 promotor.

19 d by the glutamic acid decarboxylase (GAD)67 promotor.

20 expression of luciferase driven by the ATGL promotor.

21 ression was achieved with a myocyte-specific promotor.

22 aldosterone responsiveness to a heterologous promotor.

23 ttraction suppressors, and strong-attraction promotors.

24 m caspases from tumor suppressors into tumor promotors.

25 gulates its interaction with endogenous ATGL promotors.

26 ermis after topical application of the tumor promotor 12-O-tetradecanoyl-phorbol-13-acetate (TPA) was

27 With NIS/TfOH as the promotor, 2,6-di-tert-butyl-4-methylpyridine as the base

28 , Th1 cells from T-bet-/- mice manifest IFNG promotor accessibility as detected by histone acetylatio

29 ut overall disturbed DNA-binding ability and promotor activation.

30 Gl also produced a marked inhibition of IL-2 promotor activity as determined by transient transfectio

31 state-13-acetate plus ionomycin-induced IL-2 promotor activity by 18%, 28%, 39%, and 54%, respectivel

32 and mutant p53Ala143 enhanced the EGF-R core promotor activity in cells that were either p53-deficien

33 Ca2+-sensitive involucrin AP-1 promotor activity was increased, both in HHD keratinocyt

34 TLR4 promotor activity, as well as AP-1 activation and the ef

35 uciferase reporter gene assay showed reduced promotor activity.

36 2B1 gene driven by the cytomegalovirus (CMV) promotor ad.CMV-2B1 was constructed and used to infect a

37 Under the control of the APETALA3 promotor, AGAMOUS is misexpressed in the second whorl of

38 ing luciferase under the control of an NF-kB promotor, allowing in vivo monitoring of inflammation, w

39 uced transcriptional activity of the HIV LTR promotor, an effect that required both NFkappaB and SP1

40 Sequencing detected 13 polymorphisms (three promotor and 10 coding) among 288 AR patients.

41 or on podocytes under control of the nephrin promotor and develop glomerulosclerosis when a specific

42 trong [cytomegalovirus (CMV) immediate early promotor and enhancer] or an intermediate strength (Molo

43 A showed disproportionally higher amounts of promotor and exon sequences and lower intron and interge

44 recipitation enrichment analysis of the CD55 promotor and found KLF4 binding sites upstream from the

45 of the serum-inducible element in the c-fos promotor and GAS which resembles the INF-gamma activatio

46 amoxifen-inducible Cre driven by a ubiquitin promotor and induced Cre activity in culture.

47 , increased histone acetylation at the FOXP3 promotor and induction of FOXP3 transcription.

48 hibiting transcription factor binding to its promotor and subsequently impairs IgE-mediated signaling

49 hibiting transcription factor binding to its promotor and subsequently impairs IgE-mediated signaling

50 -1 promotor, the virus established an active promotor and this contributed to the acute infection of

51 For Pt-based catalysts, metal promotors and additives, such as Ga and Si, have been sh

52 Many nucleosome linker DNA sequences, the promotors and enhancers, are suggestive of optimal expos

53 -induced reduction of H3K9me3 marks at these promotors and further repressed these EndMT-related gene

54 genomic structure, position of the proximal promotor, and intron-exon border sequences of the 30-exo

55 ns expressing GFP under control of the dmrt3 promotor are analyzed.

56 specific DNA target site for CRP and the lac promotor are located within thermalite II.

57 combination of chromatin immunoprecipitation promotor arrays (ChIP-chip) and gene expression profilin

58 control of a glial fibrillary acidic protein promotor (AstroCD24TG mice).

59 ssay showed increased Sp1 binding to the Arf promotor at 24 and 48 hours after Tgfbeta treatment, at

60 Traditional promotor-based viral gene expression techniques, however

61 that two adjacent mutations in the HBV core promotor (C to T at nucleotide 1768 and T to A at nucleo

62 In particular, we demonstrate that promotors can adjust the thermodynamics of key transform

63 These results suggest that reaction promotors can be viewed as an integral component of the

64 ays was assigned to its nearest gene and its promotor capture Hi-C interacting gene and performed exp

65 entally, we confirm that by varying the base promotor concentration one can control catalyst speciati

66 ults in the activation of transcription from promotors containing the cAMP response element (CRE).

67 The -167/-105 segment of the EGF-R promotor contains one perfect and several imperfect cons

68 LB/neuT mice, expressing rat neuT under mmtv promotor control, spontaneously developed tumorous lesio

69 regulation process by a bifunctional folding promotor controlling the folding status of biologically

70 reach program was developed that made use of promotores de salud (community health promoters) to incr

71 gonucleotide treatment also enhanced the p53 promotor-directed transcription in vivo along with the i

72 ist treatment induced E2F-1 binding to FoxC2 promotor directly and improved FoxC2 transcription.

73 onditional deletion of Dhps or Eif5a by Emx1 promotor-driven Cre expression (E9.5, in the cortex and

74 Mice with smooth muscle protein-22alpha promotor-driven deficiency of the disintegrin and metall

75 MC4-R promotor-driven GFP expression was found in PVH cells pr

76 Promotor-driven reporter gene labeling of the cells unde

77 revin, under the control of the pan-neuronal promotor elav to label the neuropil in the live animal.

78 ription factor that binds the B-box internal promotor element of tRNA genes and the complex of TFIIIA

79 has located a number of potential A-form DNA promotor elements in the Xenopus genome, five of these p

80 The interactions between enhancers and promotor elements that control gene expression are gener

81 mation, such as gene expression patterns and promotor-enhancer interactions, in order to identify dis

82 dissociation of PU.1 and YY1 from the FCER1A promotor, evaluated by chromatin immunoprecipitation.

83 beta'-2L form), a high concentration of this promotor favored the formation of polymorphic forms sugg

84 fluorescent protein driven by the endogenous promotor for Pdgfra was shown to be a powerful new tool

85 The promotor for this gene and the alternatively spliced exo

86 slated region of the viral genome, acts as a promotor for viral replication and thus is critical for

87 The target-sites on the transferrin receptor promotor for YY1 lie in close proximity to those of the

88 which provides expression control via the T7 promotor) for large-scale recombinant protein expression

89 osis, and its expression is repressed by its promotor H3K9me3 deposition.

90 Independent of carriage and DEFB promotor haplotype, a 1-unit increase in the IFN-gamma t

91 Notably, deleterious mutations in promotors have disproportionally negative fitness effect

92 and the analysis of its function at the Dbh promotor implicated Hand2 in the control of noradrenergi

93 A was created through insertion of the Pnpt-promotor in front of the NRPS gene.

94 is regulated by DNA methylation of the nNOS promotor in soleus (Sol; slow-twitch fibre dominant) and

95 the beta cell Ag IGRP under the MHC class II promotor in the NOD8.3 model.

96 arrying HA-tagged CLC-2 with an RPE-specific promotor in the subretinal space of CLC-2-KO mice at the

97 ng and expression of these genes with strong promotors in A. terreus, have been initiated, to constru

98 of acute-phase responsive and cytokine gene promotors in response to inflammation.

99 regulation, whereas p53 binding to TRAILR1/2 promotors increased upon MDM2 inhibition.

100 cer mechanisms are distinct in UV- and tumor promotor-induced cancer models and indicates that chemop

101 ed FH expression in hepatocyte by preventing promotor inhibition.

102 rotein (GP) under the control of the insulin promotor (Ins2) were stained for neuropeptide Y before,

103 nd luciferase constructs driven by IGF-II P3 promotors into multiple cell lines.

104 While the role of reaction promotors is often discussed in view of their chemical r

105 SP1 binds the IL-1beta promotor, leading to the down-regulation of its transcri

106 PEAT1 or LPEAT2 under the control of the 35S promotor led to morphological changes opposite to what w

107 luated by transient transfection of the hCAR promotor-luciferase reporter constructs, followed by pro

108 ne THP-1 were transfected with an NF-kappa B promotor/luciferase construct and activated.

109 egions were identified, wherein the proximal promotor mediated PDGF-BB inhibition of transcription.

110 ival, as well as an association between MGMT promotor-methylated tumors and PTEN positivity shown by

111 II, it is unclear whether the extent of MGMT promotor methylation and its prognostic role is independ

112 s a strong positive correlation between MGMT promotor methylation and survival, as well as an associa

113 MGMT promotor methylation is associated with favourable outco

114 MGMT promotor methylation was quantified using Sanger sequenc

115 Collectively, extent of MGMT promotor methylation was strongly associated with other

116 tructural rearrangements and conservation of promotor motifs.

117 ch overexpresses Cyfip1 under the endogenous promotor, observing an increase in the proportion of mat

118 ostasis and, once perturbed or injured, as a promotor of atherogenesis.

119 tial tumour suppressor genes at 9p21 and the promotor of CDKN2A has been unable to explain genetic pr

120 ray scattering to understand the impact of a promotor of crystallization, palmitic acid (PA), at high

121 ion assay demonstrated that MYC binds to the promotor of FAM83H and that MYC promotes the transcripti

122 ved in overweight animals and suggested as a promotor of hypertension and LVH.

123 We identified neuropeptide Y (NPY) as a promotor of liver metastasis.

124 and acetylated histone H4K5 and H4K12 on the promotor of the CCM1 and CCM2 genes.

125 of the pro-inflammatory M1 phenotype; and a promotor of the pro-resolving M2 phenotype, thus acting

126 Cu has a dual nature in carcinogenesis as a promotor of tumor growth and an inducer of redox stress

127 cervical spinal gray matter with a focus on promotors of axon growth through the growth-inhibitory a

128 B-type ARRs bind to the promotors of HEMA1 and LHCB6 genes, indicating that cyto

129 They may also be promotors of positive microbial modulation by stimulatin

130 pon re-exposure to IFNgamma, specifically at promotors of primed genes.

131 yeloid cells (by using the lysozyme M [LysM] promotor) or specifically in DCs (by using the Cd11c pro

132 utation, but no mutations are present in the promotor, or protein coding sequences or splice sites of

133 AMOUS gene under the control of the APETALA3 promotor (pAP3::AG).

134 promotor Pspc; (ii) the beta-lactamase gene promotor Pblaof plasmid pBR322; (iii) the PLpromoter of

135 ort, long) at the serotonin transporter gene promotor polymorphism (5-HTTLPR) locus of SLC6A4 now exi

136 The glial fibrillary acidic protein (GFAP) promotor possesses an AP-1 binding site, the target for

137 Consistent with this, compact promotor-proximal sequences are sufficient for string fu

138 include (i) the spc ribosomal protein operon promotor Pspc; (ii) the beta-lactamase gene promotor Pbl

139 A 160-bp fragment encompassing the promotor region and the putative iron boxes of the fbpA

140 t the two adjacent mutations in the HBV core promotor region are responsible for the enhanced replica

141 as with DEXI expression, interacted with the promotor region of DEXI but not with candidate DNA fragm

142 ith high-temperature treatment, modified the promotor region of Gsdf and Dmrt1 by demethylating the t

143 to inhibit interactions between PrbP and the promotor region of rplK, resulting in reduced survival o

144 ur an integration of a Doc retroposon in the promotor region of RpS3a.

145 Recently, in the promotor region of the HO-2 gene a consensus sequence of

146 I footprint analysis in the upstream 260 bp promotor region of the human DBH gene, of which two site

147 To analyze the promotor region of the human macrophage-stimulating prot

148 omolog (PTEN), and methylation status of the promotor region of the MGMT gene were analyzed from tumo

149 We show here that the promotor region of the rate-limiting lipolytic enzyme, a

150 we report a detailed characterization of the promotor region, the 5'- and 3'-untranslated region (UTR

151 ncing of the CpG sites 74-98 within the MGMT promotor region.

152 e addition of the first operator site in the promotor region.

153 ed macrocycle and prevents its return to the promotor region.

154 resulted from the hypermethylation in their promotor regions (Drd1, MAO, BDNF).

155 ifferential DNA methylation occurring in the promotor regions for four Cancer Genome Atlas cancer coh

156 We also observed hypermethylation at the promotor regions of autophagy genes (LC3B, ATG-5, and AT

157 ion has therefore focused on studying G4s in promotor regions of disease-related genes.

158 hat searches for occurrences of TFBSs in the promotor regions of up/down regulated or random genes.

159 DNA methylation of the INS1 and INS2 gene promotor regions was very low, and not different among R

160 cription initiation sites and their flanking promotor regions were identified, wherein the proximal p

161 ally-associated DNA domains (TADs) that link promotor regions with distant enhancers.

162 sensus MYCN binding E-box sequences in their promotor regions, suggesting they represent direct targe

163 all of which contain CRE sites within their promotor regions.

164 in, IL-10, and binding of SMAD3 to the IL-27 promotor regions.

165 ific G-quadruplex structures formed in their promotor regions.

166 chanisms and their dependence on the mode of promotor regulation remain unclear.

167 d to IFN-stimulating response element (ISRE) promotor regulation.

168 under control of a tetracycline-repressible promotor, removal of doxycycline resulted in detectable

169 In this study, promotor-reporter assays in yeast and Drosophila S2 cell

170 riven from distinct brain cell-type specific promotors, repressed with aging, and integral in coordin

171 ontrol of the endogenous Tas1r1 and Tas2r131 promotor, respectively.

172 n induces the binding of CD74-ICD to the SP1 promotor, resulting in the up-regulation of SP1 expressi

173 uences of the sequential 5' deletions of the promotor revealed that multiple positive and negative re

174 We have generated transgenic rat insulin promotor (RIP)-CXCL10 mice expressing CXCL10 in the beta

175 e, cytosine deaminase expressed from the CMV promotor seems to be the most promising toxin gene for h

176 immunoglobulin heavy chain germline epsilon promotor sequence (Iepsilon) in an electrophoretic mobil

177 n to be modulated by various factors such as promotor, solvent, anomeric ratio of donor, nature of ac

178 specific DNA motifs in the 1000 bp proximal promotor, some of which associate with known transcripti

179 by chromatin immunoprecipitation followed by promotor-specific quantitative polymerase chain reaction

180 ted O(6)-methylguanine-DNA methyltransferase promotor, standard temozolomide (TMZ) has, at best, limi

181 t with another CARD protein, interferon-beta promotor stimulator protein-1 (IPS-1, also known as MAVS

182 to be largely responsible for the increased promotor strength of this particular allelic form of the

183 Through promotor-swap experiments, the expression profile of eac

184 e) using a tetracycline-controlled inducible promotor system.

185 These results suggest that WAP promotor-targeted Int3 function is associated with mamma

186 Testing for BRAF(V600E) and TERT promotor (TERTp) mutations was performed on genomic DNA

187 is a potent antiapoptotic protein and tumor promotor that is expressed in both small cell lung cance

188 ed reactions often make use of additives and promotors that affect reactivity patterns and improve ca

189 ult of hyperacetylation of histones on HIV-1 promotor, the virus established an active promotor and t

190 Tripalmitin was also used as a promotor to assess the impact of fatty acid esterificati

191 tion in the context of a zebrafish rhodopsin promotor to convert its specificity from rod-only expres

192 PGs in limiting regeneration, using the gfap promotor to express a CSPG-degrading enzyme chondroitina

193 osed complexes between this polymerase and a promotor to open complexes in a reaction that depends up

194 We have used the rat tyrosine hydroxylase promotor to overexpress MYCN in the neural crest of tran

195 ciferase vector with a cytomegalovirus (CMV) promotor to porcine donor hearts prior to heterotopic im

196 P, was found to bind to HBV enhancer I and X promotor to repress the production of HBV pregenome RNA

197 surface layer of peroxide species acts as a promotor to significantly enhance CuO reducibility in fa

198 sing POP2 controlled by its endogenous human promotor to study the immunological functions of POP2.

199 We leveraged this collection of inducible promotors to construct simple two-channel logical contro

200 the ability of cell-specific AAV capsids and promotors to specifically target ON-BCs for gene deliver

201 ) or specifically in DCs (by using the Cd11c promotor) to acute and chronic house dust mite (HDM)-dri

202 tor of crystallization, and palmitic acid, a promotor, to investigate the influence of the chain leng

203 ld-type mouse skin in response to the tumour promotor TPA.

204 Chicken ovalbumin upstream promotor-transcription factor I (COUP-TFI), an orphan me

205 quires a catalyst (typically iron, Fe) and a promotor (typically sulfur, S), their synergistic roles

206 serotonin transporter genotype at the SLC6A4 promotor VNTR polymorphism in 30 healthy subjects who al

207 enge, but only within areas where the CYP1A1 promotor was already active.

208 ssion of h2-calponin using a cytomegalovirus promotor was independent of the stiffness of culture mat

209 Absence of nucleosomes from the LTP-promotor was not sufficient to provoke robust transcript

210 at contains a reporter coupled to the HOXA13 promotor we identify single HOXA13-positive cells distal

211 induced by activation of a doxycycline (Dox) promotor, we tested the effects of Tat on cocaine (10 mg

212 acromolecular regulators as volume-exclusion promotors, weak-attraction suppressors, and strong-attra

213 ounts of IL-10 under the control of the IL-2 promotor were infected with M. tuberculosis via the resp

214 cal system, we developed a synthetic folding promotor whose reactivity is up-regulated under stress c

215 r the control of the liver activator protein promotor with transgenic mice carrying a constitutively