ライフサイエンスコーパス: pronounced

1 M-TGFbeta2-induced changes being mostly more pronounced.

2 nscriptional target gene FLT3 being the most pronounced.

3 a similar way although their effect was less pronounced.

4 processes, the extent of inhibition is less pronounced.

5 tween the two STN was high, slowing was more pronounced.

6 rst HHF, CRT-D therapy was associated with a pronounced 44% reduction in risk of subsequent HHF (haza

7 USP51 deubiquitinating enzyme, leading to a pronounced accumulation of ubiquitinated chromatin.

8 The immunodeficiency was marked by a pronounced actin polymerization defect and a strongly re

9 The pronounced additive effect of HDAC inhibition in DNA met

10 bcc1 ((-/-)) rats, but differences were more pronounced after intratracheal than after intravenous ad

11 ction, increased presence of C-circles, more pronounced ALT-associated phenotypes and elongated telom

12 similar AAP risk, whereas morbidity was most pronounced among adolescents.

13 l counts revealed differences that were more pronounced among allergic asthmatics than among controls

14 en, the effect of bariatric surgery was more pronounced among ER-negative cases (HR = 0.36, 95% CI, 0

15 The NLR-BC association was more pronounced among Luminal A BC (multivariable OR for the

16 The reduction was more pronounced among the CD8(+) population, resulting in an

17 This effect was most pronounced among those aged >=75 years.

18 ent (n = 1,212), this pattern was especially pronounced among vaccinated individuals who perceived va

19 tribution describes the first observation of pronounced amplification of absorption in low contrast o

20 tently high in BMM s and SOCS3 expression is pronounced and long lasting in T cells.

21 ia, as induced by an insulin bolus, was more pronounced and prolonged in ghrelin-KO mice, supporting

22 ctivation of parietal cortex not only caused pronounced and selective reductions of salience signals

23 h reported beta-lactam allergy resulted in a pronounced and sustained increase in perioperative cefaz

24 onated/neutral form of the drug induced more pronounced and/or distinct alterations in the structure

25 Particularly, EOs exhibit pronounced antibacterial and food preservative propertie

26 A pronounced antigenic variation was noted in swIAV, and s

27 rated that this pair of compounds exhibits a pronounced antimetastatic effect.

28 In conclusion, pronounced antioxidant activity, repression of the PPARg

29 s (3+1) hybrid-2 topology, which became more pronounced as further G-quadruplex units are added.

30 fferences from old-growth forest become more pronounced as logged forests increase in stature over ti

31 ifferences in LHH by age and sex became more pronounced as statin-associated T2D RR increased, with a

32 erested researchers for decades due to their pronounced asymmetries at the population level.

33 ty among adhesion fibroblasts, which is more pronounced at early timepoints.

34 ciated with cancer-related genes become more pronounced at invasive breast cancer stage.

35 as detectable at PND1, the changes were more pronounced at PND21, suggesting a potential role of post

36 af occupancy upon depletion of Kin28 is more pronounced at TFIID-dominated promoters compared to SAGA

37 preference for feeding sites exhibited more pronounced behavioural adjustments during the manipulati

38 tumour mutational burden seem to have a less pronounced benefit with targeted therapy (HR [versus pla

39 Measurement variability was most pronounced between baseline measurement and 30 seconds a

40 ween the two mammalian SAR1 paralogs lead to pronounced biochemical differences that significantly af

41 gand with an 80 angstrom linker had the most pronounced bivalent effects, with a significantly slower

42 Differential gene expression was most pronounced by sex, race/ethnicity, and body mass index (

43 iation with RF-IgA levels appeared even more pronounced, by six-fold more P. gingivalis (P = 0.025),

44 rats are perhaps protected against the more pronounced changes in CSF and gray matter volumes observ

45 this massive, high-latitude eruption led to pronounced changes in hydroclimate, including seasonal t

46 n basal or evoked arterial dilation, despite pronounced changes in the LFP.

47 Acute depletion of TPR causes rapid and pronounced changes in transcriptomic profiles.

48 d computationally (TD-DFT calculations), the pronounced charge transfer character of the longest wave

49 We also noted that cells exhibited a pronounced clustering phenotype when exposed to near-inh

50 atients, the group known to receive the more pronounced CM connections was significantly weaker.

51 t-specific BAF60a inactivation triggers more pronounced cold-induced browning of inguinal white adipo

52 , the deterioration of red pigments was more pronounced compared to that of the yellow pigments.

53 n of PIVC during attentive tracking was less pronounced compared with sham rTMS.

54 Advanced maternal age at birth can have pronounced consequences for offspring health, survival a

55 rboreal primates such as chimpanzees exhibit pronounced curvature in their hand and foot phalanges, w

56 ed a higher tumor-to-kidney ratio and a more pronounced cytotoxic effect than did (177)Lu-DOTATOC.

57 The most pronounced decrease in cell counts is observed for CD8 T

58 ion of functional architecture in mice and a pronounced decrease in modularity that was not observed

59 M. truncatula, and this was accompanied by a pronounced decrease in the expression of many of the key

60 cts on soil micro-food webs, leading to more pronounced decreases at higher trophic levels (nematodes

61 cells lacking either Put6 or Put7 exhibit a pronounced defect in proline utilization, which can be c

62 cells fail to differentiate properly, with a pronounced deficiency in neuronal differentiation.

63 nhibition of Tac2(Cre) neurons also displays pronounced deficit in chronic dry skin itch, a type of c

64 of PP1 stabilizes cyclin B and results in a pronounced delay at the metaphase-to-anaphase transition

65 n indiscriminate stochastic process, we find pronounced demethylation of young long interspersed elem

66 The presence of virus in blood and pronounced detection in reproductively active males sugg

67 y lymphoid progenitors in mice resulted in a pronounced developmental arrest in early T cell developm

68 from the first postnatal week onwards, with pronounced developmental increases in H(3) receptor expr

69 l treatment-31% versus 22% (P < 0.0001)-with pronounced differences for Gram-negative bacteria and Ca

70 ase-specific enrichment of immune cells with pronounced differences in proportional abundance of tiss

71 stances measured within the same domain show pronounced differences in their unfolding behavior, unde

72 l (70% and 70% versus 57%; P <= 0.003), with pronounced differences observed using samples collected

73 hough the mechanisms that give rise to these pronounced differences remain incompletely understood, t

74 particles within the zeolite crystals impose pronounced diffusion limitations on reaction intermediat

75 There was also a pronounced discrepancy in terms of efficiency across stu

76 The most pronounced discrimination is seen against RNAs ending wi

77 This was accompanied by a selective and pronounced disruption of cell-type-specifying transcript

78 ards greater discontinuity, characterised by pronounced downstream declines in channel size and local

79 soon is characterised by transitions between pronounced dry and wet seasons, affecting food security

80 rferon-gamma (IFN-gamma) secretion, was more pronounced during C. glabrata infection.

81 esent in SIB to a lesser extent and are more pronounced during high cognitive demand, thus possibly r

82 As seasonality is particularly pronounced during interglacial periods, this raises the

83 ampal-neocortical dynamics were particularly pronounced during long-duration compared to short-durati

84 medial and lateral prefrontal regions, most pronounced during processing of unpleasant stimuli.

85 lar differentiation, an effect that was less pronounced during proliferation or after TNF-alpha expos

86 The closed N cycling became pronounced during the first 3 years of warming where the

87 This difference was most pronounced during the first week of follow-up.

88 T) in the absence of doxycycline resulted in pronounced early-onset and progressive neurodegeneration

89 biomes, also known as ecotones, are areas of pronounced ecological change.

90 n of ozone, and pulsed light at 10 V) showed pronounced effect compared to other non-thermal processi

91 quenching of core dynamics accompanied by a pronounced effect in mAb binding.

92 infections throughout pregnancy, with a more pronounced effect in the first trimester of pregnancy.

93 Light had a more pronounced effect in the RAS-B system, while flow affect

94 incipal Component Analysis (PCA) highlighted pronounced effect of thermal processing on juice compare

95 rtant source of secondary BrC and can have a pronounced effect on atmospheric chemistry and air pollu

96 locations based on available data can have a pronounced effect on epidemiological predictions, affect

97 l variations in temperature or pH can have a pronounced effect on the observed kinetics that can mani

98 low GSP treatment having a similar but less pronounced effect on these attributes.

99 The most pronounced effect was noted among patients who were in s

100 The lipid compositions of GUVs have pronounced effects on in vitro TBSV replication, includi

101 ved that the rectangular obstacles have more pronounced effects on obstructing the flow of turbidity

102 trophils and macrophages, IgA1 does not have pronounced effects.

103 that oblate spheroids, some of which have a pronounced equator defining a spinning top shape, can fo

104 Bennu have an oblate spheroidal shape with a pronounced equator, but contain different surface hydrat

105 tant responded to intense activity with more pronounced facilitation.

106 8 eV above the pristine bandgap and displays pronounced ferromagnetic hysteresis.

107 mortality of A. selaginoides and resulted in pronounced floristic, structural vegetation, and fuel lo

108 It is shown that a pronounced focusing peak takes place when the focal poin

109 This effect is more pronounced for ATZ than with AAT and is only partially d

110 ats, whereas this diversity pattern was less pronounced for bacteria.

111 genes in prenatal brain development is more pronounced for childhood-onset disorders, such as autism

112 y digestible starch, an effect that was more pronounced for cooked starch.

113 tric disorders, yet this association is more pronounced for disorders with a clear neurodevelopmental

114 its response to chemical stimuli being more pronounced for higher resistive states.

115 The latter effect is especially pronounced for microparticles under the soft contact reg

116 For number of mistakes the effect was less pronounced for more experienced surgeons.

117 Differences were most pronounced for MSM with >10 recent sex partners, and par

118 d a cost in reduced body mass which was more pronounced for North Rona, Outer Hebrides (NR) mothers.

119 elf-judgments, and this effect was even more pronounced for other-judgments.

120 ifference was from the MERINO trial was less pronounced for piperacillin/tazobactam.

121 This effect was most pronounced for raltegravir- (HR=1.42 [1.06-1.91]) vs. NN

122 Distribution patterns are much more pronounced for some populations of OFF BC cells than oth

123 se associative memory biases were especially pronounced for stimuli rated as more affectively salient

124 experimentally, that these effects are more pronounced for the anionic phosphatidylserine lipids tha

125 Risk was more pronounced for those with additional family history of C

126 Pronounced functional crosstalk was observed between the

127 erence in neighborhood mutation risk is less pronounced further away from the focal CpG and modulated

128 ls displayed severe developmental delay with pronounced generalized hypotonia, respiratory insufficie

129 B cell lymphoma (DLBCL) is confounded by its pronounced genetic, phenotypic, and clinical heterogenei

130 Cyclosporine led to a more pronounced global transcriptome reversion and normalized

131 The pronounced glycocalyx of bladder cancer cells enhanced t

132 se without transplants, p=0.003), and a less pronounced hemodynamic response to regadenoson (mean inc

133 More pronounced histopathology changes were detected in the c

134 f resting neuronal Ca(2+) signalling yielded pronounced homeostatic synaptic plasticity, suggesting a

135 se inter-individual differences constitute a pronounced human phenotype.

136 This spontaneous gap opening shows pronounced hysteresis and other signatures characteristi

137 e encephalomyelitis (EAE) model and observed pronounced immunomodulation evident by a reduction in pr

138 hromosomal integration events illustrate the pronounced impact of coevolution with these extrachromos

139 s South Korea and Singapore, reported a less pronounced impact on nuclear medicine services; however,

140 tion of more methoxy groups had subtler, but pronounced, impacts on either ERalpha binding or MCF-7 c

141 emperature effects on these traits were less pronounced, implying antagonistic stressor effects on mo

142 We show that this activity is more pronounced in a mutant version of the A(1)-receptor (A(1

143 eal and intraepidermal neuronal loss is more pronounced in advanced stages of DR, indicating a positi

144 patients, CS-induced effects were similarly pronounced in ALI cultures from patients compared to hea

145 Indirect effects are expected to be more pronounced in alpine environments because these ecosyste

146 poorer CRC-specific survival, which is most pronounced in cases carrying TP53 mutations with predict

147 driven carbonate chemistry that will be most pronounced in cold temperatures.

148 f whi2 and psr1psr2 strains are particularly pronounced in dense spatially structured colonies and ar

149 oitation, cascading effects that may be more pronounced in drier forests where conditions have select

150 The effect of HFD was more pronounced in female mice after VDR deletion.

151 ersistent diabetogenic phenotype, especially pronounced in female offspring after developmental expos

152 over widespread regions of the cortex, most pronounced in frontal and parietal cortices; and (c) a s

153 lt of input occurrence data source were most pronounced in future climate projections.

154 This is even more pronounced in gadolinium, curium's lanthanide analogue,

155 urosphere growth and these effects were more pronounced in GSCs of the PN subtype.

156 This is especially pronounced in high-risk (FRS7-10) patients, who demonstr

157 hippocampal 5-HT(1A) binding which was more pronounced in HV.

158 optotic effects by P. zopfii GT-II were more pronounced in macrophages compared to MECs.

159 Strikingly, iron depletion was more pronounced in MDR cells due to the Pgp-mediated efflux o

160 ounterintuitively, disease markers were more pronounced in Mer residents.

161 ender segregation across occupations is more pronounced in more egalitarian and more developed countr

162 e results to show that subadditivity is most pronounced in more posterior aspects of the pSTG.

163 This response was more pronounced in Neil2 knockout (KO) mouse cells than in WT

164 The response to regadenoson was less pronounced in obese and diabetic patients.

165 Median LOS benefit was most pronounced in patients with coagulase negative Staphyloc

166 hemodynamic response to regadenoson is less pronounced in patients with heart transplants than in pa

167 y and mean diffusivity differences were most pronounced in patients with hippocampal sclerosis in the

168 MiR-214 induction was pronounced in perivascular and circulating T cells, but

169 were driven by rectal subsites and were most pronounced in persons aged 50 to 54 years, in whom recta

170 Treatment benefits are more pronounced in persons with more advanced liver fibrosis.

171 the synergistic effect of AM-ADSCs was more pronounced in preventing catabolic responses in activate

172 al and radial diffusivities in 22q11DS, most pronounced in regions with major cortico-cortical and co

173 , and the fertilization effect appeared more pronounced in SG.

174 k of dental insurance is expected to be more pronounced in states that have not expanded Medicaid or

175 These processes were more pronounced in summer when particles were most acidic, wh

176 ls, and the effect is, for good reason, most pronounced in tall species.

177 n body mass and early life survival was most pronounced in the 1st year of life.

178 However, nystagmus was more pronounced in the BS-Cat group (US-Cat: 12.16%; BS-Cat:

179 The destabilizing effect of heparin is more pronounced in the case of the longer chains due to the e

180 (T2) immune signature of BALF cells was more pronounced in the eosinophilic subphenotype of N-ERD.

181 yte function following loss of NFIA are most pronounced in the hippocampus, manifested by impaired in

182 However, these rearrangements are less pronounced in the KPC-4 than the KPC-2 ceftazidime acyl-

183 This trend is more pronounced in the late than the early half of the famili

184 environment-an effect that was particularly pronounced in the narrow part of the trapezoid.

185 dry-down period (17-19 days), which was more pronounced in the NT due to larger evapotranspiration an

186 ownregulation by VR23 was significantly more pronounced in the primary synovial cells from rheumatoid

187 Most pronounced in the Pyrenees, the enhanced pine recruitmen

188 Flood seasonality is also more pronounced in the recent period.

189 e observed that FXR1 alternative splicing is pronounced in the serine- and arginine-rich intrinsicall

190 imply that the cooling would have been more pronounced in the Southern Hemisphere.

191 The warming mode is most pronounced in the tropics.

192 were the carotenoid levels and this was more pronounced in the uncommon non-orange varieties.

193 Pathology is pronounced in the upper and lower respiratory tract, and

194 .00%; P < .001), whereas strabismus was more pronounced in the US-Cat group (US-Cat: 68.92%; BS-Cat:

195 xtreme polygenic risk was substantially more pronounced in those with elevated alcohol consumption or

196 differences were correlated with GA and more pronounced in those with GA of <=30 weeks.

197 This increase was more pronounced in women (from 1.8% in the first cohort to 4.

198 n response to binge EtOH treatment were more pronounced in young relative to older animals, negating

199 ral responses to speech stimuli, with a more pronounced increase at moderate than at high sound inten

200 VLCD yielded a pronounced increase in fasting acylcarnitine levels, whe

201 Surgery was associated with a pronounced increase in inflammatory biomarkers in both C

202 The more pronounced increase in osteoprotegerin suggests that thi

203 ted in protein aggregation, evident from the pronounced increase in particle count (by MFI).

204 Vulnerable mice exhibited a pronounced increase in running throughout the light cycl

205 CD8(+)T(M) maintenance is associated with a pronounced increase of XCL1 production capacity; chemoki

206 ith P. falciparum For both species, the most pronounced increase was seen in osteoprotegerin.

207 tome, with the LNG-IUS transcriptome showing pronounced inflammation and immune activation compared t

208 oadly downregulated and subdermal fat showed pronounced inflammation.

209 alyzed the specificity of DNMT1, revealing a pronounced influence of the DNA sequences flanking the t

210 erably between individuals, pointing to more pronounced inter-individual differences than previously

211 The most pronounced interactions were found between quinine and N

212 Recombinant virus VSV-P(DeltaOD) exhibits a pronounced kinetic delay in progeny virus production.

213 Absence of CTHRC1 results in pronounced lethality attributable to ventricular rupture

214 lineages in African North Americans reflects pronounced limitations in the African genomic database,

215 We also show that TbPolIE displays pronounced localization at the nuclear periphery, and th

216 ination of excitatory synapses with the most pronounced loss observed in deeper cortical layers.

217 cross the Northwest Coast, which indicated a pronounced marine diet for Tseshaht dogs and, presumably

218 Our results reveal a pronounced Middle Holocene excursion (peaking ~7,000-6,0

219 Pronounced modifications to immune facilities are associ

220 d limited metabolic activity changes vs. the pronounced mutational burden and ESCC-associated metabol

221 sing conventional deposited Au contacts with pronounced n-type characteristics.

222 ical than horizontal quadrants, and was most pronounced nasally.

223 we found that type I collagen fibrils show a pronounced nonlinear behavior in the form of strain stif

224 tensity and lifetime, consistent with a more pronounced nonradiative decay.

225 les from the island species was particularly pronounced on the X-chromosome.

226 by simple hydrothermal treatment and exhibit pronounced optical properties with a high quantum yield

227 Pronounced organism-wide morphological stasis in evoluti

228 ll endo/exo diastereoselectivity, as well as pronounced ortho/meta regioselectivity for reactions per

229 nding and moreover demonstrated the need for pronounced overall flexibility in the PRORP1 enzyme conf

230 pic skin alterations were significantly more pronounced (P < 0.0001) 5 days after irritation.

231 CR induces pronounced postprandial peaks in hepatic adropin express

232 Our analysis revealed pronounced predator-mediated shifts in prey habitat use

233 scovered that Aire-sensitive genes display a pronounced preference for short-3'UTR transcript isoform

234 ipheral myelin protein 22 (PMP22) exhibits a pronounced preference for, promotes the formation of, an

235 mutations in LMNB1 in seven individuals with pronounced primary microcephaly (ranging from -3.6 to -1

236 cycle, however, which includes a brief, but pronounced, prolactin peak, oscillation frequency remain

237 htened Th-1 immune response that would yield pronounced protective vaccine efficacy.

238 roteomic profiling of NPC lysosomes, we find pronounced proteolytic impairment compounded with hydrol

239 Yet, pronounced reaction rate decrease for benzyl alcohol alk

240 generalized and extratemporal epilepsies had pronounced reductions in fractional anisotropy in the co

241 In F7, extreme temperature resulted in more pronounced reductions in grazing, and nauplii production

242 five interacting proteins exhibited the most pronounced relative change between breeds.

243 An in vitro simulation showed a more pronounced release in the small intestine with a vitamin

244 rmionic quasi-particle dispersion exhibits a pronounced renormalization, signaling a giant coupling t

245 rt robust SARS-CoV-2 replication and develop pronounced respiratory disease, which may more accuratel

246 Most notably, pronounced sagittal crests are negatively correlated wit

247 ata suggest that musculature associated with pronounced sagittal crests-and accompanied increases in

248 rom both fresh and old carbon sources showed pronounced seasonality in vegetated zones.

249 The campaign revealed a pronounced seasonality of the TFA concentration and wet

250 The pronounced selectivity can be further enhanced by loweri

251 splay high affinity, long residence time and pronounced selectivity.

252 Therefore, ATD knockout cells display pronounced sensitivity through increased mistranslation

253 Single strands of RNA display pronounced sequence-dependent conformations that relate

254 Here we uncover pronounced sexual dimorphism in T(reg) cells in the VAT.

255 ate, high-fat ketogenic diets (KDs) induce a pronounced shift in metabolic fuel utilization that elev

256 diated by piezomechanical SAWs, we observe a pronounced, significant maximum of the cell-growth rate

257 noyl-substituted model system to explain the pronounced solvent dependency of the carbenoid stability

258 Metal concentrations exhibited pronounced spatial variation, primarily driven by anthro

259 Urban environments are characterized by pronounced spatiotemporal heterogeneity, which can prese

260 e NMR supports these predictions and reveals pronounced spectral differences for the same polymer in

261 In the rat, recovery is accompanied by pronounced spontaneous plasticity of axotomized and spar

262 (2) of concentration >500 p.p.m. triggered a pronounced stimulatory effect on vagal bronchopulmonary

263 in diagrams at lower velocities V manifest a pronounced strength decrease over small distances, where

264 plasticity with higher forces, indicating a pronounced stress stiffening of the cytoskeleton.

265 Moreover, the pronounced temperature dependence of the anisotropy that

266 Among eyes with worse VA, variation was more pronounced than among eyes with better VA; eyes 20/25 or

267 globally and nowhere are their affects more pronounced than in island ecosystems.

268 ty degeneration in the erector spina is more pronounced than in multifidus, and the erector spina is

269 transformed cells from both species was less pronounced than in transformed human cells, suggesting t

270 interferon signature; however, this was less pronounced than in viral encephalitis.

271 Interestingly, albeit less pronounced than in wt mice, in IFNAR(-/-) and Enbrel-tre

272 ation for body weight was significantly more pronounced than the association for BMI (P < 0.001).

273 substituents on five-membered rings are less pronounced than those on six-membered rings because of t

274 erged in control treatments, but it was less pronounced than under snow removal.

275 Vanadium dioxide (VO(2)) features a pronounced, thermally-driven metal-to-insulator transiti

276 e response of FrA pyramidal neurons was more pronounced to Gaussian noise than to pure frequency tone

277 rocessing traits are apparently sufficiently pronounced to play a role in community assembly because

278 which are widely anticipated to become more pronounced under future climate and land use change.

279 This is particularly pronounced under the periodic boundary conditions common

280 Community changes were less pronounced under wetter postmortality conditions.

281 The TISF occurs at ~175 K and becomes more pronounced upon increasing the temperature toward room t

282 These mice also had pronounced upregulation of osteopontin and RUNX2 (osteog

283 We observed pronounced variation (excess of 3-fold) in standardized

284 oss of corticospinal drive contribute to the pronounced weakness found in triceps.SIGNIFICANCE STATEM

285 e cyclical seasonal changes, frequently with pronounced wet and dry seasons, leading to a highly unev

286 waters on Fe availability will be much more pronounced when Fe is present as iron oxyhydroxide compa

287 ambient CO(2) concentration, which are most pronounced when g(m) is small.

288 95% CI (0.063; 0.243)], which was even more pronounced when individuals had been diagnosed by a clin

289 ask-dependent activity in V1 LPZ became less pronounced when JMD patients opened their eyes, suggesti

290 This pattern was more pronounced when low DO coincided with high temperature.

291 These differences can become increasingly pronounced when scaling from controlled laboratory to op

292 However, this potential was not pronounced when the cells were kept under 37 degrees C.

293 ism and growth, and this effect on growth is pronounced when their diet is limited to the algal speci

294 y warmer locations richness increase is more pronounced while abundance declines with warming.

295 These thermomechanical effects become more pronounced with heavier mechanical damage due to an incr

296 Liver uptake was more pronounced with higher minibody masses.

297 This interaction with older age became more pronounced with incident VI (N = 168), where decrements

298 Changes in community structure were most pronounced with LV-Co, and correlated with biomarkers of

299 t of GC disengagement was significantly more pronounced with stenoses located in proximal and middle

300 swelling, this discrepancy becomes even more pronounced, with the thickness of P3HHT films changing b