ライフサイエンスコーパス: pronucleus

1 ng de novo H3K27me3 modification on the male pronucleus.

2 e of a low level de novo H3K9me2 in the male pronucleus.

3 e events precede the development of the male pronucleus.

4 is not inherently less than that of the male pronucleus.

5 a sperm nucleus reorganizes to become a male pronucleus.

6 ormation of the nuclear envelope of the male pronucleus.

7 ration of histone variant H3.3 into the male pronucleus.

8 abnormal incorporation of H3.1 into the male pronucleus.

9 mechanisms that regulate H3K9me2 in the male pronucleus.

10 rming sperm DNA into a mitotically competent pronucleus.

11 e female pronucleus migrates toward the male pronucleus.

12 t propels the anterior migration of the male pronucleus.

13 nd 5-carboxylcytosine (5caC) in the paternal pronucleus.

14 ale pronucleus anteriorly to join the female pronucleus.

15 rces necessary to translocate and center the pronucleus.

16 We show here it also positions the male pronucleus.

17 3K9me3 levels, respectively, in the maternal pronucleus.

18 h a single centrosome detached from the male pronucleus.

19 asymmetric furrows assembling from the male pronucleus.

20 synthesized and stored in the sea urchin egg pronucleus.

21 ind replication of DNA derived from the male pronucleus.

22 ndle that forms in association with the male pronucleus.

23 vesicle movement) to formation of a distinct pronucleus.

24 of polar bodies and the formation of the egg pronucleus.

25 ng the early stages of migration by the male pronucleus.

26 o five times greater than that of the female pronucleus.

27 conversion of the sperm nucleus into a male pronucleus.

28 tablished around the metaphase-arrested male pronucleus.

29 3K9 trimethylation (H3K9me3) in the paternal pronucleus after fertilization is catalysed by SUV39H2 a

30 on of the male pronucleus to meet the female pronucleus after fertilization requires Arp2/3.

31 GNU eggs are inseminated, however, the male pronucleus also undergoes DNA replication.

32 gation of somatic chromosomes into a zygotic pronucleus and a polar body.

33 mic flows that are directed toward the sperm pronucleus and aggregate at the posterior cortex during

34 that CI occurs independently of the maternal pronucleus and argues against pronuclear asynchrony as t

35 al position of centrosomes, between the male pronucleus and cell cortex at the embryo posterior, is a

36 ion of cyclinE/cdk2 into the male and female pronucleus and entry into first S-phase.

37 The suSLBP is concentrated in the egg pronucleus and is released from the nucleus only when ce

38 s shortly after fertilization when the sperm pronucleus and its associated centrosomal asters provide

39 ation and posterior movement of the paternal pronucleus and its associated centrosome.

40 ronucleus or asynchrony between the paternal pronucleus and the cell cycle of the egg cytoplasm.

41 ociation must be maintained between the male pronucleus and the centrosomes during pronuclear migrati

42 hem became stably associated with the female pronucleus and the remaining cytoplasmic asters rapidly

43 in favor of DDK alleles at Om in the female pronucleus and TRD in favor of C57BL/6 alleles at Om in

44 cyclinE and cdk2 accumulation in both sperm pronucleus and zygote nucleus in vivo.

45 mpermeable eggshell, migration of the oocyte pronucleus, and the separation and expansion of the sper

46 se that robust MT nucleation pushes the male pronucleus anteriorly to join the female pronucleus.

47 The male pronucleus assembles within the fertilization cone and i

48 s, the protein is associated with the female pronucleus at the animal pole in the unfertilized egg, b

49 (2) The newly formed pronucleus begins transcription of histone messages.

50 finding shows that Wolbachia impair the male pronucleus but no extranuclear component of the sperm.

51 gs whose normal development requires no male pronucleus but still depends on extranuclear paternal fa

52 rols both the morphology and function of the pronucleus by fine-tuning microtubule dynamics.

53 ole in orchestrating asymmetric division and pronucleus centration.

54 cle (fue) is required in the zygote for male pronucleus-centrosome attachment and female pronuclear m

55 en postulated to be a component of the sperm pronucleus/centrosome complex (SPCC) as the position of

56 vanced pronuclear-stage zygotes the paternal pronucleus contains substantial amounts of 5hmC but lack

57 ein 1 beta (HP1beta) is abundant in the male pronucleus, despite the absence of di- and trimethyl H3-

58 thus ensuring the formation of a viable male pronucleus during early embryonic development.

59 atin: safeguarding the integrity of the male pronucleus during female meiosis.

60 achia-induced sperm modification is the male pronucleus (e.g., DNA or pronuclear proteins) or some ex

61 n, the centrosomes associated with the sperm pronucleus fail to closely associate with the posterior

62 ufficient to support polar body emission and pronucleus formation after only a single sperm-induced C

63 at inhibits nuclear transport, also prevents pronucleus formation and causes Ca(2+) oscillations that

64 ranscription is first detected shortly after pronucleus formation in 1-cell embryos, but the identity

65 A role for pronucleus formation in regulating Ca(2+) signalling is

66 nalling is demonstrated in experiments where pronucleus formation is inhibited by microinjection of a

67 Male pronucleus formation is inhibited upon deletion of Hira

68 e of a nuclear envelope and independently of pronucleus formation, is regulated by factors associated

69 As a consequence of the lack of pronucleus formation, sperm-triggered Ca(2+) spiking con

70 ately 4 hours, stopping close to the time of pronucleus formation.

71 rogenote production by transferring the male pronucleus from one zygote into another haploid androgen

72 s been associated with protecting the female pronucleus from TET3-mediated demethylation.

73 Knockdown of Lsm1 disrupts nonequilibrium pronucleus histone incorporation and asymmetric H3K9me3

74 sperm entry site and trajectory of the male pronucleus in a significant majority of eggs.

75 as been reported to occur along the paternal pronucleus in fertilized oocytes in an apparently replic

76 layed nuclear envelope breakdown of the male pronucleus in Nasonia vitripennis.

77 1B is down-regulated, oocytes fail to form a pronucleus in response to Ca(2+) signals.

78 females show defective formation of the male pronucleus in vivo.

79 Further, the genome of the oocyte pronucleus, including information regarding aneuploidy a

80 In this model, a centrosome pair at the male pronucleus initiates stochastic microtubule (MT) growth.

81 ly nucleate actin and further accelerate the pronucleus inwards.

82 Incorporation by the male pronucleus is always about four to five times greater th

83 of the sperm nucleus into a functional male pronucleus is compromised in sarah mutant eggs, indicati

84 sions: Selection and migration of the female pronucleus is independent of the sperm and its aster.

85 pecific H3 methylation reveals that the male pronucleus is negative for di- and trimethyl H3-K9 yet t

86 , the transcriptional capacity of the female pronucleus is not inherently less than that of the male

87 neither the sperm chromatin mass nor a sperm pronucleus is required for spermiogenesis, proper egg ac

88 C. elegans is specified by sperm, the sperm pronucleus itself is not required.

89 efective for the function of either the male pronucleus (mh, K81, and pal or both pronuclei (gnu, png

90 g a microtubule aster along which the female pronucleus migrates toward the male pronucleus.

91 fertilization cone and is required for male pronucleus migration toward the center of the zygote.

92 is also observed on the surface of the male pronucleus (MPN) in vivo during NE formation.

93 e exon 2 of Osr1 were microinjected into the pronucleus of a mouse zygote, 34% of the embryos had del

94 rminal repeat promoter and injected into the pronucleus of fertilized oocytes of Sprague-Dawley rats

95 LEK1 protein is detected exclusively in the pronucleus of the oocyte and was not observed in other a

96 nduced the appearance of H3K9me2 in the male pronucleus of the zygote treated with cycloheximide.

97 genetic development (i.e., from the paternal pronucleus only).

98 ither a developmentally incompetent paternal pronucleus or asynchrony between the paternal pronucleus

99 ein is either in specification of the female pronucleus, or in migration of the male and female pronu

100 clear decondensation, form a functional male pronucleus, or initiate mitotic divisions in the egg.

101 s, the amount of incorporation by the female pronucleus present in parthogenetically activated eggs i

102 bolishes incorporation of H3.3 into the male pronucleus, renders the paternal genome unable to partic

103 t recruitment of lamina proteins to the male pronucleus requires, and probably accompanies, reorganiz

104 diction that the Wolbachia-modified paternal pronucleus should support androgenetic development (i.e.

105 unmethylated before it was injected into the pronucleus, so it is a good model to study the inheritan

106 s expressed in a pattern that appeared to be pronucleus-specific and maintained a nucleus-specific pa

107 with female pronuclei prior to loss in late pronucleus stage embryos.

108 of H3-K9 with DNA methylation, in the female pronucleus, suggests a mechanistically significant link.

109 iate nucleosome assembly in the nascent male pronucleus, the machinery for protamine removal remains

110 MT-length-dependent pulling forces drag the pronucleus through the cytoplasm.

111 The sperm aster then captures the female pronucleus to join the maternal and paternal genomes.

112 n one-cell embryos the migration of the male pronucleus to meet the female pronucleus after fertiliza

113 Two of these MTOCs join the female pronucleus to set up the first mitotic spindle in unfert

114 is the case in the zygote where the paternal pronucleus undergoes active DNA demethylation shortly af

115 hed histone H3K9 methylation in the maternal pronucleus was suggested to protect the underlying DNA f

116 tment of nuclear lamina proteins to the male pronucleus, we examined the subcellular localization of

117 udies emphasizing pulling forces on the male pronucleus, we propose that robust MT nucleation pushes

118 iations would place CidB at the zygotic male pronucleus where CI defects first manifest.

119 41) Centrosomes remain tethered to the sperm pronucleus, which positions them near the cortex to esta

120 The converse is true for the maternal pronucleus, which retains 5mC but shows little or no 5hm

121 scous nuclear drag is sufficient to move the pronucleus, while simultaneously generating minus-end di

122 rental genomes cluster with nucleoli in each pronucleus within human and bovine zygotes, and clusteri