1 or pure proteins in microarray format, as a
proof of concept.
2 trate the usefulness of data unification and
proof of concept.
3 ssels from Cav-1(-/-) mice were used to test
proof of concept.
4 enome design, using genome minimisation as a
proof-of-concept.
5 ach toward these heterolayered dendrimers as
proof-of-concept.
6 As a
proof of concept,
a rapid assay consisting of a cell-bas
7 A
proof-of-concept administration study employing an in vi
8 As a
proof of concept,
aflatoxins, ochratoxin A, and deoxyniv
9 Proof-of-concept ambient measurements were performed in
10 As a
proof-of-concept,
an X-ray phase contrast under bending
11 S binding signals were detected, prompting a
proof-of-concept analysis of human serum samples.
12 To demonstrate
proof of concept and estimate effect size, we performed
13 Our data provide an important
proof-of-concept and model system for the potential use
14 e limitations of PTAs, but also provides the
proof-of-concept application of BP-based materials in PE
15 In a
proof-of-concept application, we isolated bacteria from
16 As
proof-of-concept applications, we used the octapeptide t
17 In a
proof-of-concept approach, we explored a clinically tran
18 atible, demonstrating data transmission as a
proof-of-concept at kHz speed level, and potential data
19 We demonstrated
proof-of-concept based on detection of "activated" matri
20 The
proof-of-concept battery delivers reasonable electrochem
21 Overall, this work provides a
proof-of-concept bioassay for simple and portable molecu
22 The
proof-of-concept bioelectronic devices include electroph
23 As a
proof of concept,
botanical samples were digested by MIC
24 We provide a
proof-of-concept by using SOLVING to quantitate the orie
25 sign is verified using a breadboard and FPGA
proof of concept circuit and passes all 15 of the NIST r
26 ighly advantageous group in which to conduct
proof-of-concept clinical trials that target tau-related
27 evidence is now leading to the initiation of
proof-of-concept clinical trials using senolytics for se
28 As a
proof of concept,
Co(OH)(2) was selectively recovered fr
29 We apply this new methodology to
proof-of-concept controls, and demonstrate that it works
30 Our findings provide
proof-of-concept data for engineering patient-specific j
31 volved only a small cohort, these meaningful
proof-of-concept data now warrant further investigation
32 This study provides
proof-of-concept data supporting the use of complex coac
33 Here, we report a novel strategy with
proof-of-concept data that supports the usage of loop-me
34 We provide a
proof-of-concept demonstration by genetically transformi
35 We provide a
proof-of-concept demonstration in the GEDmatch database,
36 This
proof-of-concept demonstration may aid the development o
37 As a
proof-of-concept demonstration, the permeability of endo
38 ing process(5), which-although versatile for
proof-of-concept demonstrations(6-16) and fundamental st
39 The
proof-of-concept device has 20 sensors and a 45-degree f
40 It is hoped that his
proof-of-concept device with machine-learning-based appr
41 al of targeted miRNA therapeutics, and, as a
proof of concept,
effectively counteract common inflamma
42 As a
proof of concept,
eighteen essential amino acids at phys
43 Here, we report a direct coupled,
proof-of-concept electrochemical system that uses a bipo
44 As a
proof-of-concept,
electrooxidative C-H/N-H coupling and
45 We then use the model in a
proof-of-concept example.
46 study's concentration-response function in a
proof-of-concept example.
47 ted by loss of Dnmt3a activity; this genetic
proof-of-concept experiment suggests that this approach
48 In a
proof-of-concept experiment using this technology in an
49 As a
proof-of-concept experiment, we demonstrate a functionin
50 Finally, we report the
proof-of-concept experiment, where detection sensitivity
51 We report
proof-of-concept experiments in which a positive subsamp
52 Proof-of-concept experiments showed that the presence of
53 During these
proof-of-concept experiments, the approach led to the st
54 Our
proof-of-concept findings support the adoption of dual-m
55 sfer (MS-CPET) activation of a C-H bond in a
proof-of-concept fluorenyl-benzoate substrate.
56 This study demonstrates the
proof of concept for 1D and 2D NMR methods in the target
57 Gonda and colleagues provide preclinical
proof of concept for a new therapeutic strategy and addr
58 We present a
proof of concept for a spectrally selective thermal mid-
59 This paper reports on the
proof of concept for a stretchable microfluidic device t
60 Here, we demonstrate
proof of concept for an adjunctive therapy that allows i
61 Therefore, our results offer a
proof of concept for an alternative treatment to chemoth
62 These results provide
proof of concept for an approach that could reduce the s
63 bocyclic nucleoside analogues and provided a
proof of concept for application as inhibitors for the p
64 The
proof of concept for conditionally activatable photocage
65 e preclinical development and first-in-human
proof of concept for DSR.
66 otics alone.CONCLUSIONThis study establishes
proof of concept for exebacase and direct lytic agents a
67 This work provides a
proof of concept for fundamental catalytic action of the
68 Mecp2 p.R294X mutation in vivo and provide a
proof of concept for future preclinical studies of nonse
69 ak of the current conflict, and they provide
proof of concept for how geospatial techniques can be us
70 Conclusion: These studies provided a
proof of concept for many proposed applications for a PE
71 Findings provide
proof of concept for MPI insertion in the clinical biops
72 Proof of concept for OSPW source identification using di
73 As a
proof of concept for super-resolution applications, we u
74 oid-mediated immune suppression and provides
proof of concept for targeting this pathway for tumor im
75 iated osteomyelitis, and then we validated a
proof of concept for the lateral flow assay (LFA).
76 The data here reported constitutes the first
proof of concept for the potential application of the pe
77 Our initiative offers a
proof of concept for the repurposing of existing approac
78 Previous studies served to demonstrate the
proof of concept for the use of quantum confined semicon
79 These results provide a
proof of concept for understanding age-related vascular
80 More broadly, this research demonstrates a
proof of concept for using remote sensing to detect forc
81 aims at finding suitable cathodes to achieve
proof-of-concept for a full Ca battery, the spectrum of
82 Our goal in this study is to provide a
proof-of-concept for a non-invasive assay of global mole
83 Our results provide
proof-of-concept for a paradigm of microbially-derived b
84 em and method presented showcase a promising
proof-of-concept for granting an exclusively light-trigg
85 alence among GBM with HIV-infection provides
proof-of-concept for HCV micro-elimination.
86 ing from experimental data, and we provide a
proof-of-concept for how they could form the basis of a
87 Our results offer a
proof-of-concept for modifying synthetic nanogels with a
88 These findings provide
proof-of-concept for targeting spinal Wnt signaling for
89 As
proof-of-concept for the discovery of novel P2X receptor
90 Here, we establish a
proof-of-concept for the molecular sieving separation of
91 o and endosperm development have facilitated
proof-of-concept for the synthesis of apomixis, bringing
92 These results provide the first
proof-of-concept for the usage of low-power light source
93 iated with ALDH7A1 deficiency and provides a
proof-of-concept for the utility of the model to study P
94 e of TLR4-PI3-kinase signaling and providing
proof-of-concept for therapeutic interventions aimed at
95 As a
proof-of-concept,
FOREST discovers multiple RNA-protein
96 The
proof of concept herein points to a mechanistic basis fo
97 In a
proof-of-concept human study on the therapeutic, we foun
98 nditions, and a drop-off of efficacy between
proof-of-concept (
i.e., Phase II trials) and pivotal, co
99 Application of the
proof-of-concept illustrated here, using a feedback loop
100 Proof-of-concept in 2 independent genomic loci suggests
101 This work may provide a
proof-of-concept in developing technically and economica
102 Herein, we report
proof-of-concept in vivo efficacy in an streptozotocin-i
103 Subsequent
proof-of-concept in vivo studies demonstrated that, when
104 evidenced by the preliminary results from a
proof-of-concept in-vivo experiment of tracking an indiv
105 As a
proof of concept,
in situ separation and imaging of lipi
106 ions and challenges in achieving preclinical
proof-of-concept,
including in vivo mitophagy reporter m
107 As
proof of concept,
industrial wastewater was investigated
108 Two
proof-of-concept inorganic probes that exploit a novel m
109 In vivo
proof-of-concept investigations revealed that 12c displa
110 A
proof of concept is conducted by using the LoTToR on a p
111 The
proof of concept is demonstrated by detecting different
112 A
proof of concept is given, and the design of the device
113 A
proof of concept is shown using a ketone mixture introdu
114 As a
proof-of-concept,
it is demonstrated that these material
115 Finally, as a
proof of concept,
iTrEnDi was used to produce diazoethan
116 unprecedented transformation, albeit at the
proof of concept level, offers a new approach toward a c
117 The robustness, shown using strychnine as a
proof of concept,
makes the J-based CASE-3D analysis a v
118 A
proof-of-concept material in a cantilever setup is used
119 aterial is reported, using Mg(2) TiO(4) as a
proof-of-concept material.
120 n of sunscreen products for an FDA-sponsored
proof-of-concept maximal usage clinical trial.
121 We present a
proof-of-concept method to infer the total tumour pressu
122 We use a computational approach to propose a
proof of concept model showing that a single, simple net
123 Our goal was to develop a
proof-of-concept model for identifying subjects at high
124 We 3D printed an optical
proof of concept multi-element lenslet array to confirm
125 These
proof-of-concept observations offer a promising step tow
126 Herein, we present the
proof of concept of a self-powered platform that operate
127 As a
proof of concept of its manufacturability, biocompatibil
128 Our results present an important
proof of concept of RCA-FRET imaging with a strong poten
129 These findings serve as
proof of concept of synergistic antitumour activity with
130 Thus, this study established the
proof of concept of targeting TF as a new target in CAR-
131 This work demonstrates the important
proof of concept of the ability of pyrogallol[4]arene to
132 Here we present
proof-of-concept of a biological self-restoring system t
133 The results represent a
proof-of-concept of a new algorithm of personalized anti
134 egies may be safe and effective and provides
proof-of-concept of a potential strategy that may allow
135 Here, we demonstrate
proof-of-concept of a solid-phase technique coupling the
136 It is proposed that fermented cabbage is a
proof-of-concept of dietary manipulations that may enhan
137 antimicrobial activity, thereby serving as a
proof-of-concept of drug reformulation to minimizing oto
138 f biotinylated glucose oxidase (biot-GOx) as
proof-of-concept of the analytical application of MWCNTs
139 Proof-of-concept of the applicability of the microfluidi
140 Preliminary results suggest
proof-of-concept of using the ECochG response as a micro
141 Here, we first present an experimental
proof of concept on a tissue-mimicking phantom and then,
142 Here we demonstrate a
proof-of-concept on-chip transducer using trivalent ytte
143 Exemplarily, as
proof of concept,
one nontarget pollutant was identified
144 As a
proof of concept,
our workflow was applied to the toxico
145 tanding of the processes involved beyond the
proof-of-concept,
particularly for selective methane oxi
146 In this
proof-of-concept,
prospective non-randomized study carri
147 successfully extended to the synthesis of a
proof-of-concept proteolysis-targeting chimera (PROTAC),
148 The
proof of concept reported here is the first step toward
149 This work demonstrates a
proof-of-concept responsive drug-release system that may
150 activities have yet to be determined, these
proof-of-concept results demonstrate that this novel ass
151 Herein, we report
proof-of-concept results on a versatile synthetic strate
152 As
proof of concept,
results showed that INSeq screens succ
153 The
proof-of-concept scheme consists of a spinning core made
154 As a
proof of concept,
sensors were produced to detect the ne
155 In addition, studies using the
proof-of-concept small molecule inhibitors of ICMT confi
156 assifier was integrated with the device as a
proof-of-concept so that sensor's response can be traine
157 The
proof-of-concept solar cell and light-emitting diode dev
158 directly challenges these views and provides
proof-of-concept solutions examined for a transient ther
159 last two decades, the field has grown from a
proof of concept stage to a broad range of methods for a
160 ibrary of 250 DNA parts and assemblies and a
proof-of-concept strain that illustrates cAMP-chemotaxis
161 This work provides a
proof-of-concept strategy for processing and integrating
162 We report a
proof-of-concept structured light generation experiment,
163 Furthermore,
proof-of-concept studies demonstrate that treatment with
164 ency, solubility, and lipophilicity to allow
proof-of-concept studies in mice.
165 These
proof-of-concept studies indicate that alphaDR5-NPs load
166 , and perform extensive characterization and
proof-of-concept studies of mSncg promoter-mediated gene
167 electrode materials, application of scalable
proof-of-concept studies, and acknowledgment of all trea
168 In
proof-of-concept studies, this cp-Fab/CAR-T system targe
169 Hence, each model can be evaluated in "
proof-of-concept"
studies of preconception vaccination a
170 This
proof of concept study demonstrates that mD-LC/MS has th
171 This
proof of concept study targets the translational rigor o
172 ure (IdeS digestion x reduction-HILIC/MS), a
proof of concept study using two mAbs is described here.
173 As a
proof of concept study, both the H(2) O(2) and (1) O(2)
174 In this
proof of concept study, we demonstrate the feasibility o
175 This
proof-of-concept study demonstrates that behavioral phar
176 Collectively, this
proof-of-concept study demonstrates that empowering pati
177 This work represents a novel
proof-of-concept study demonstrating the feasibility of
178 C compared with liver tissue, we conducted a
proof-of-concept study evaluating the efficacy of 3'-deo
179 This
proof-of-concept study has demonstrated that hyperpolari
180 Overall, this
proof-of-concept study has supported the development of
181 This
proof-of-concept study highlights the mechanisms underly
182 This
proof-of-concept study holds promise as a novel immunoth
183 A
proof-of-concept study in mouse demonstrates the potenti
184 This single-center retrospective
proof-of-concept study included 32 patients with documen
185 epare and to subsequently perform a clinical
proof-of-concept study on the general suitability of sil
186 This
proof-of-concept study presents Raman hyperspectroscopic
187 Collectively, this
proof-of-concept study provides a first example of photo
188 Our
proof-of-concept study provides a powerful new methodolo
189 This
proof-of-concept study shows how integration of microfab
190 This positive
proof-of-concept study supports the continued developmen
191 We demonstrate in a
proof-of-concept study that Ce6-PVP-based fluorescence e
192 Here, we present a
proof-of-concept study to noninvasively derive the therm
193 The phase 2a,
proof-of-concept study was an open-label, adaptive dose-
194 Methods: In this
proof-of-concept study, 11 patients with lymphoma of the
195 In this
proof-of-concept study, an extensive structure-activity
196 ) and investigated on clinical isolates as a
proof-of-concept study, but requiring longer incubation
197 In a
proof-of-concept study, Der p 1 and OVA levels were dete
198 Here, we used, in a
proof-of-concept study, matrix-assisted laser desorption
199 Conclusion In this
proof-of-concept study, percentage of T1 shortening at e
200 In our
proof-of-concept study, we furthermore demonstrate, on e
201 In this
proof-of-concept study, we included people living with H
202 Based on this first
proof-of-concept study, we propose multi-scale phase con
203 Conclusion: In this
proof-of-concept study, we showed the potential of back-
204 In this
proof-of-concept study, we sought to evaluate the variat
205 In a
proof-of-concept study, we supplemented PA to therapy-na
206 In the current
proof-of-concept study, we tested whether virus reactiva
207 In this
proof-of-concept study, we used high-resolution mass spe
208 of this study was to perform a preclinical "
proof of concept"
study of Bergamot polyphenolic formula
209 We used our approach in
proof-of-concept "
synthetic" in silico experiments, in w
210 The
proof-of-concept system provides a unique technological
211 Therefore, this
proof-of-concept technique shows significant potential f
212 fied with high recoveries under a battery of
proof-of-concept testing scenarios in various matrices.
213 Taken together, these findings provide
proof of concept that adoptive immunotherapy using ex vi
214 The
proof of concept that an enantioselective version of thi
215 These results provide an experimental
proof of concept that changes in locomotor behaviour and
216 Our study provides
proof of concept that data-driven, automated, operator-i
217 kinase pathway component B-Raf, providing a
proof of concept that human signaling kinases identified
218 This data provides the
proof of concept that local administration of HB-EGF has
219 This represents a
proof of concept that rational engineering of HCV envelo
220 rapeutic resistance, but they also provide a
proof of concept that targeted inhibition of this axis m
221 for the development of T2D therapeutics and
proof of concept that the capping strategy can be used o
222 tiple tumor-relevant promoters, we provide a
proof of concept that the system can implement logic gat
223 Furthermore, we have obtained
proof of concept that the use of Singapore Greens for pr
224 This serves as
proof of concept that understanding how CRM1(E571K) affe
225 These data provide an exciting
proof-of-concept that aminoglycosides or other readthrou
226 aim of the present study was to demonstrate
proof-of-concept that candidate drug combinations could
227 Thus, this preclinical study provides
proof-of-concept that combining antiparasite MIF-blockin
228 The present study provides the first
proof-of-concept that fat-specific cold mimetics via act
229 This work is not only a
proof-of-concept that HDX-MS can be used to get structur
230 anded CMV-specific CD8+ T cells has provided
proof-of-concept that immunotherapy can be highly effect
231 Our study provides a
proof-of-concept that it is possible to discriminate ant
232 We provide
proof-of-concept that it is possible to influence the ta
233 This work provides a
proof-of-concept that LNP formulation of DNA vaccines ca
234 These results provide
proof-of-concept that MHC-E-restricted CD8(+) T cells co
235 We also provide
proof-of-concept that polarized HLCs can be used for pha
236 This study provides the first
proof-of-concept that stable, hydrophobic oxidovanadium
237 This case study provides the
proof-of-concept that the correlation methods developed
238 This study provides a
proof-of-concept that the plant-soil feedback concept ca
239 PD1 during radiation responses and establish
proof-of-concept that this pathway can be targeted with
240 As a
proof of concept,
the applicability of this system to en
241 experimental data and DFT calculations, as a
proof of concept,
the capacity to utilize the Mn-MOF for
242 Eventually, as a
proof of concept,
the designed biosensor was successfull
243 As a
proof of concept,
the obtained CeO(2) -based SOMMs show
244 For a
proof of concept,
the technology platform was tested wit
245 As
proofs-of-concept,
the rGO-PLA electrode was applied for
246 A
proof-of-concept therapy study with a single administrat
247 As a
proof of concept,
this (13)C NMR dereplication strategy
248 As a
proof-of-concept,
this technique was then applied to hai
249 As a
proof of concept,
three peptide substrates derived from
250 Here we used a cell culture system as
proof of concept to show that, upon exposure to a satura
251 The new metric was used as a
proof-of-concept to assess transplant-program access com
252 vertible mEos expressed as intrabodies, as a
proof-of-concept to perform single-particle tracking on
253 We provide a
proof-of-concept to show how Raman spectroscopy can be u
254 faces of the cholangiocyte channel, allowing
proof-of-concept toxicity studies with the biliary toxin
255 (ADME) properties, which was progressed into
proof-of-concept translation of in vitro antiparasitic a
256 2-week, double-blind, randomized, controlled
proof-of-concept trial of prazosin (16 mg/day, with a 2-
257 ion at single-cell resolution and provides a
proof-of-concept using this method to identify SINE acti
258 As a
proof of concept,
various Int derivatives have demonstra
259 As a
proof-of-concept we analyze the htTPM signal for two DNA
260 As
proof of concept,
we applied FLEXIQuant-LF to data-indep
261 As a
proof of concept,
we characterized the function of the h
262 As a
proof of concept,
we characterized the molecular identit
263 As a
proof of concept,
we conducted the first-ever extensive
264 As a
proof of concept,
we demonstrate a four-step conversion
265 As a
proof of concept,
we developed a 5-plex assay measuring
266 As a
proof of concept,
we developed a microfluidic PCR workfl
267 As
proof of concept,
we functionalized 47 missense variants
268 As a
proof of concept,
we have used this CRISPR-E test in the
269 As a
proof of concept,
we investigate the Ras-Raf system, a w
270 As a
proof of concept,
we performed digital LAMP on a sp-Slip
271 As a
proof of concept,
we present the potential for the devel
272 As a
proof of concept,
we propose herein to monitor the photo
273 For
proof of concept,
we select the gastrointestinal drug me
274 Applying our framework to Germany as a
proof of concept,
we show significant losses in function
275 As a
proof of concept,
we show that rTCP96 reduces LPS-induce
276 As a
proof of concept,
we show that SS-31 alters divalent cat
277 As
proof of concept,
we simulate a revised kidney allocatio
278 hus, using adenine de novo biosynthesis as a
proof of concept,
we suggest that the engineering method
279 For
proof of concept,
we tested PNAs targeting miRNA-155 and
280 As a
proof-of-concept,
we analyzed the elemental profiles of
281 As a
proof-of-concept,
we demonstrate a design of a sensor fo
282 As a
proof-of-concept,
we demonstrate how the molecular calor
283 As
proof-of-concept,
we demonstrate the efficient operation
284 As
proof-of-concept,
we employed net-clipping to form three
285 As a
proof-of-concept,
we first investigate the utility of CO
286 For
proof-of-concept,
we generated DVD-ARCs targeting variou
287 As a
proof-of-concept,
we generated Solanum tuberosum (potato
288 As a
proof-of-concept,
we have synthesized a nanocrystal-base
289 With this
proof-of-concept,
we hypothesize that biofeedback traini
290 As a
proof-of-concept,
we manufactured and characterized the
291 As a
proof-of-concept,
we propose a novel approach for castin
292 As a
proof-of-concept,
we recount the successful engineering
293 For initial
proof-of-concept,
we selected Mef2d, which when overexpr
294 As a
proof-of-concept,
we show that an OCS pipeline focused o
295 As a
proof-of-concept,
we show that joint DA of multiple inde
296 As a
proof-of-concept,
we use an i-motif as the nucleic acid
297 As a
proof-of-concept,
we used this technique to measure the
298 rmacokinetics properties and finally in vivo
proof-of-concept while ensuring selectivity over related
299 As the
proof-of-concept work, multichannel series piezoelectric
300 A
proof-of-concept workflow study for the fabrication of c