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2 ver that genetic deletion of Gravin disrupts proper accumulation and asymmetric distribution of gamma
3 cleotide-binding regions of myosin assures a proper actin-binding interface and active site have form
5 nsmission modulating therapeutics, even with proper adherence and acceptable tolerability, are not ef
6 susceptible to motion artifacts as they lack proper adhesion and conformal interfacing with the skin
7 ng by peptide vaccination in the presence of proper adjuvants or in vitro expansion of the low number
8 scent devices, including the requirement for proper alignment of material energy levels and the need
13 on: 1) maintenance of growth within the wing proper and 2) induced growth of surrounding "pre-wing" c
14 n-induced gluconeogenesis, thus preventing a proper and complete adaptation to nutrient deprivation.
16 it protein complex that is essential for the proper architecture of the mitochondrial inner membrane.
17 lkalinization also occurred within the cleft proper at the active zone and not just within extrasynap
18 ch is known to be a crucial molecule for the proper attachment of epithelium to tooth/implant surface
19 curate chromosome segregation depends on the proper attachment of kinetochores to spindle microtubule
20 ehensive evaluations show that DESC offers a proper balance of clustering accuracy and stability, has
24 Moreover, compensatory responses leading to proper behavioral strategies and active resilience are u
26 eported results are also validated through a proper biological significance test and heatmap plotting
27 (2020) reveal that PYRC2 is a key enzyme for proper brain development and a regulator of glycine home
34 Bipolarity of the spindle is crucial for the proper cell division, and two centrosomes in animal cell
37 t phenotype-associated noncoding variants in proper cell types and relevant dynamic conditions, to mo
38 components is essential, and to ensure this, proper characterization is needed, which requires design
39 s the likelihood of lithium metal plating if proper charging controls are used, alleviating a major s
41 lated in the early stages, controlled by the proper chloroplast differentiation and by the PHYTOCHROM
42 vant shows a distinct mechanism of action, a proper choice is necessary to craft an effective vaccine
43 dependent function of NuMA in choreographing proper chromatin decompaction and nuclear shape by direc
45 leosome recognition is required by ISW1a for proper chromatin organization at promoters; as well as t
47 homologous recombination, which facilitates proper chromosome segregation and enables the reciprocal
56 n efficient signal transduction by providing proper conformation and avoiding futile cross talks.
58 al RNA helix 74, which is required to ensure proper construction of the NPET and 60S ribosomal subuni
59 The necessity of cMyBP-C phosphorylation for proper contractile function is well-established, but the
61 ighly abundant bystanders, how to select the proper controls to minimize false discoveries, and exper
62 te how, despite rigorous experimentation and proper controls, our understanding of the mechanism of g
65 f histidine-43 in structurally assisting the proper coupling between K1 and K2 and concurrently facil
67 hat membrane association is required for the proper delivery of PlsX's product to PlsY, the next enzy
71 on early in meiotic prophase is required for proper designation of chromosome subdomains and normal c
73 interneurons may play a critical role in the proper development and function of cortical circuits, ma
79 removal of self-interaction combined with a proper DFA can lead to improved descriptions of water co
82 t all these cases need further studies for a proper diagnosis, to search novel causative genetic defe
85 and thermodynamic control that maintain the proper distribution of RNA molecules between dispersed a
88 opy reveals the Y269 residue is required for proper DNA bending by APE1, providing evidence for the i
92 s for establishing matched control group for proper effect size assessment in future studies and outl
93 aspects for preservation and restoration of proper eGC nanomechanics are discussed, considering the
96 Aub germ plasm assembly pathway although its proper enrichment in the germ plasm may still rely on ce
97 GS will only realize its full potential with proper environmental screening, as well as patient sampl
98 ew ways to repair corneal defects that drive proper epithelialization and stromal remodeling of the w
100 phased stepwise research framework to ensure proper evaluation of the use of a fast MRI examination a
102 function, which is required for maintaining proper excitatory-inhibitory balance in the PFC and its
104 nown as WAGO-class 22G-RNAs are required for proper expression of spermatogenic and oogenic genes.
105 renewal but is required for establishing the proper expression signature of neural progenitor cells,
107 to support current practice is very scarce, proper filtration remains one important approach to main
109 olecular chaperone that is essential for the proper folding and assembly of myosin into muscle thick
114 ellular responses.SIGNIFICANCE STATEMENT The proper formation of axonal and dendritic morphologies is
115 ult in retinal degeneration by impairing the proper formation of the outer segment of photoreceptors,
116 r protein therapeutics is required for their proper function and the elimination of deleterious off-t
117 Protein quality control is essential for the proper function of cells and the organisms that they mak
120 ncer cells then become very dependent on the proper function of those pathways, and their inhibition
121 flexible and turned out to be essential for proper functioning of FtsH as its deletion fully elimina
125 e juvenile critical window is detrimental to proper functioning of the prefrontal cortex (PFC) and es
128 rsing the midbrain, and this is required for proper GABAergic neuronal migration into the substantia
130 ide new insight into the pathways underlying proper GIN activity while also indicating potential ther
131 egulator of integrin in the glia, supporting proper glial and extracellular matrix ensheathment of th
134 restore molecular homeostasis needed for the proper growth and fusion of palatal shelves are presente
138 dy found that administration of PRRT via the proper hepatic artery did not reproduce the increase in
143 A number of these complications require proper identification and care to optimize patient outco
144 e bone marrow hematopoiesis is essential for proper immune function, we hypothesize that SCI disrupts
145 C function may contribute to disturbances in proper immune homeostasis associated with HIV-1 infectio
146 sidues 18 and 20 of the NLS are defective in proper incorporation of nucleotides and RNA binding.
148 ent functions of Aurora B, which promote the proper interaction between spindle microtubules and chro
149 ity of radiomic features is essential to the proper interpretation of changes in these features over
153 herapy are the epitome of such concerns, and proper knowledge, interpretation and management are need
157 nesis, expression of sarcomeric proteins and proper localization of MURC in shPAB cell cultures and i
160 transport of cargo proteins from the TGN for proper location; but EPS1's impact on physiological resp
164 mia patients indicating close monitoring and proper management of the disease and comorbidities in th
174 lian central nervous system depends upon the proper migration and positioning of neurons, a process k
178 ported by PI4KB are critically important for proper myelination through control of lipid metabolism,
180 uch mechanisms in the forebrain nucleus HVC (proper name), a cortex-like sensorimotor area of songbir
181 up to 147 d) in five major song nuclei: HVC (proper name), robust nucleus of the arcopallium (RA), Ar
182 V release site organization, was crucial for proper nanoscale patterning of the BRP scaffold and need
188 ics-based phenotype prediction benefits from proper normalization techniques and state-of-the-art reg
191 iferative capacity and for the production of proper numbers of forebrain GABAergic interneurons.
192 ack tiger shrimp suggest that without having proper nutrients from the polychaetes, female broodstock
193 ial degrees of freedom or, equivalently, the proper order parameters for describing complex phenomena
195 rtant for the formation of central MT pairs, proper orientation of basal bodies, and synchronized bea
202 d showed that smooth topographical cues with proper period and orientation can efficiently orchestrat
204 , directly regulate actin assembly to ensure proper phagocytic internalization, and translocate phago
205 of mechanisms to regulate DGKepsilon ensures proper phosphatidylinositol cycle function regardless of
206 enable MICOS assembly and ultimately lead to proper physical and functional organization of mitochond
208 med in Bhutan, knowing which is critical for proper planning and successful delivery of the services.
210 ractions revealed that EPS1 was required for proper PM abundance of a discrete subset of proteins wit
212 XCR4, work in concert to coordinate both the proper positioning of B cell progenitors in the bone mar
214 wo rRNA elements in the subunit head and the proper positioning of the universally conserved head pro
215 orsen if economies begin to open without the proper precautions, including expanded diagnostic capabi
218 iagnostic value for G-AgP, it might not be a proper predictor of clinically favorable treatment outco
219 HAT1 links replication fork function to the proper processing and assembly of newly synthesized hist
226 ilter by micro-Raman spectroscopy will allow proper quantification of microplastics in complex bevera
229 rocedures, which aim at identifying the most proper reagent combination in only three distinct steps.
231 Previous studies have demonstrated that the proper recruitment of the water-permeable channel aquapo
232 e entity can be misleading when used without proper reference to other comparable entities or when ex
233 ion of hematopoietic stem cells and impaired proper regeneration of hematopoiesis after DNA damage.
234 RAS are molecular switches indispensable for proper regulation of cellular proliferation and growth.
236 ndent auxin biosynthesis and is required for proper regulation of root meristem size and root hair de
237 s require complex signaling interactions and proper regulation of these interactions to influence bio
241 storing a nearly original DG mass, promoting proper rewiring of regenerated neurons to their afferent
243 s and ecotoxicology-essential information to proper risk assessment-particle size, shape, and chemica
244 nose coronavirus disease 2019 (COVID-19) for proper risk stratification, isolation strategies, and tr
245 de-esterified pectin states is essential for proper root clock function and the subsequent initiation
248 ney, liver, and lung transplantation, with a proper selection and management of both donors and recip
249 complex task that requires one to maintain a proper sense of orientation relative to both local and g
250 Accordingly, the proposed method exhibits proper sensitivity, good repeatability, and acceptable a
251 rganization of a microtubule spindle for the proper separation of chromosomes in mitosis and meiosis.
253 endolysosomal trafficking genes required for proper SG maturation, indicating that maturation of SGs
256 thy proteome throughout life is critical for proper somatic stem cell function, but the complexities
258 IL-21 production by T(FH) cells, preventing proper spatial organization of T(FH) cells to form T(FH)
261 ee carbene coordination geometries given the proper stabilizing coordination environment from the red
262 ins is required for asymmetric divisions and proper stomatal pattern, but the cellular mechanisms tha
266 comprised of the dentate gyrus, hippocampus proper, subiculum, presubiculum, parasubiculum and the e
267 s and total folate content, which could be a proper substitute to the currently standardized but impr
268 ate technologies for drug administration and proper systems pharmacology approaches for patient data
271 g development to guide growth cones to their proper targets in both the central and peripheral nervou
274 The probability that one clock reads a given proper time conditioned on another clock reading a diffe
281 normal gross morphology of hair bundles and proper trafficking of known MET components Protocadherin
283 for more attention from our community to the proper training of undergraduates in biomedical research
284 fertilization in angiosperms depends on the proper trajectory of pollen tubes through the pistil tis
286 tic reproductive system defects suggest that proper transcriptional regulation of lag-1 confers robus
288 during reward processing, thereby impairing proper updating of motor predictions when learning in un
290 ion is made between this malpractice and the proper use of logarithmic plots in representation of cal
292 ond differently to given activation stimuli, proper validation of suitable reference genes in these s
296 of adjacent mesenchymal cells by regulating proper Wnt4 expression during root furcation morphogenes
297 results indicated that the prepared mat is a proper wound dressing for DFU management and treatment.
299 results indicate that ZIP9 is essential for proper zinc modulation during zebrafish egg activation a
300 he maternal epigenome integrity required for proper zygotic genome activation and transfer of develop