ライフサイエンスコーパス: prophylactically

1 timicrobial agents, both therapeutically and prophylactically.

2 n at the first sign of bleeding, rather than prophylactically.

3 ples collected from infected mice when given prophylactically.

4 doses of H1N1 and H3N2 IAV when administered prophylactically.

5 B), while receiving fluconazole 400 mg daily prophylactically.

6 infants from severe disease, if administered prophylactically.

7 ly with curative compounds that can also act prophylactically.

8 re is no FDA-approved agent that can be used prophylactically.

9 to whether lead revision should be performed prophylactically.

10 of tumors treated either therapeutically or prophylactically.

11 suppressed inflammatory arthritis when given prophylactically.

12 rformed only if SVC focus is recognized, not prophylactically.

13 fractured (49.4%), and 26.5% were extracted prophylactically.

14 of angiotensin-converting enzyme inhibitors prophylactically.

15 rimethoprim, and acyclovir were administered prophylactically.

16 viral replication in vivo when administered prophylactically.

17 ment of vascular disorders when administered prophylactically.

18 index influenza cases take antiviral agents prophylactically.

19 rFVIII, and resulted in low ABRs when dosed prophylactically 1 to 2 times per week.

20 In mice given NF-kappa B antisense prophylactically, 67% were fibrosis-free, whereas of tho

21 dentified during electroanatomic mapping and prophylactically ablated in appropriate patients.

22 We examined whether prophylactically administered anti-respiratory syncytial

23 Prophylactically administered BDGR-49 at 25 mg kg(-1) pe

24 Prophylactically administered nebulized bacteriophages r

25 Finally, antibiotic-treated mice prophylactically administered with succinate-producing b

26 Prophylactically, Ag-SP efficiently decreased local and

27 Remarkably, no MAb in our panel protected prophylactically against challenge by a strain from a he

28 e is a consideration as the antibody is used prophylactically against RSV and as passively administer

29 d complement (C') activity when administered prophylactically against SHIV challenge in rhesus macaqu

30 When administered prophylactically against simian-HIV challenge in rhesus

31 enting EAE development, and were active both prophylactically and after priming.

32 Antibodies showed synergy when administered prophylactically and as a therapy 48 h postinfection.

33 AD(+)-producing enzyme), was protective both prophylactically and as an intervention.

34 ola virus and Marburg virus infections, both prophylactically and postexposure in a homologous challe

35 rosis) disease development when administered prophylactically and reduced hallmarks of pathology when

36 The SA-IL-4 fusion protein may be prophylactically and therapeutically advantageous in the

37 HMPV subgroups, and 54G10 was effective both prophylactically and therapeutically against HMPV in viv

38 that cyclic tetrapyrroles may be useful both prophylactically and therapeutically against TSE disease

39 s effective in protection of H5N1 virus both prophylactically and therapeutically and appears to neut

40 This type of adduct can therefore be applied prophylactically and therapeutically and does not requir

41 fic antibodies were effective when delivered prophylactically and therapeutically in mouse models of

42 against the Omicron BA.1 variant in hamsters prophylactically and therapeutically, indicating that aR

43 fective when administered once per day, both prophylactically and therapeutically.

44 severe corneal damage when administered both prophylactically and therapeutically.

45 cacy in hamsters, reducing viral replication prophylactically and therapeutically.

46 ective against lethal pneumococcal challenge prophylactically and therapeutically.

47 d Th2 responses and airway inflammation both prophylactically and therapeutically.

48 t blocked the development of NASH when given prophylactically and therapeutically.

49 tor, has been the mainstay of treatment both prophylactically and to treat bleeding.

50 The antiviral drug provided protection both prophylactically and when given up to 2 days after i.v.

51 When given prophylactically, anti-PD1 treatment led to an increase

52 been achieved in 90% of study patients when prophylactically anticoagulating study patients with hyp

53 -glycolide) (Ag-PLG) are similarly effective prophylactically, are well tolerated by sensitized anima

54 anaphylaxis) we topically applied fingolimod prophylactically, as well as after establishment of the

55 against the hemagglutinin head administered prophylactically at 15 mg/kg reduced viral load and lung

56 When administered prophylactically at 5 mg/kg of body weight, HF5 and CD6

57 that EBOV237 conferred protection when given prophylactically at a level similar to that of the ZMapp

58 -inhibitor coagulant complex (AICC), infused prophylactically at a target dose of 85 U per kilogram o

59 ion of patients in whom an ICD was implanted prophylactically at the time of elective CABG.

60 r received oseltamivir (5 mg/kg twice daily) prophylactically before intranasal inoculation of highly

61 541 was administered perorally daily, either prophylactically (before disease onset) or therapeutical

62 When administered prophylactically, BMS-345541 (in a dose range of 10-100

63 t of damaging inflammation when administered prophylactically, but can also limit or reverse neuroinf

64 l mouse strain had the IL-1 receptor blocked prophylactically by means of a recombinant IL-1 receptor

65 attenuate ongoing epileptiform activity and prophylactically dampen subsequent seizure activity.

66 n day 0, and the animals were treated either prophylactically (days 0-16 or days 0-23) or therapeutic

67 Lewis rats with AIA were orally dosed either prophylactically (days 0-20) or therapeutically (days 10

68 wis rats with AIA were orally treated either prophylactically (days 0-20) or therapeutically (days 10

69 wed that fluconazole (400 mg/d) administered prophylactically decreases the incidence of candidiasis

70 LISA, which was most frequently given quasi-prophylactically during delivery room management.

71 ne atony in women who have received oxytocin prophylactically during the third stage of labour.

72 ematurity have prompted clinicians to use it prophylactically even before apnea.

73 of risky encounters that will not be treated prophylactically, even after significant outreach effort

74 ence that maternal prednisone should be used prophylactically, fluorinated steroids may be efficaciou

75 ary vein isolation (PVI) should be performed prophylactically for all pulmonary veins, prophylactic S

76 hat tyrosine kinase inhibitors may be useful prophylactically for protection of nontumor tissues in p

77 PZ is administered prophylactically for respiratory syncytial virus (RSV) i

78 actor (150 ug/m(2) subcutaneously) was given prophylactically from day 3 to day 6 and day 10 to day 1

79 A single dose of group B MAbs administered prophylactically fully protected mice against lethal cha

80 d also be infused perioperatively to enhance prophylactically immunity against EBV infection in high-

81 suppress Th2-type cytokine expression and to prophylactically immunize against Th2-dependent pulmonar

82 Spinal drains were placed prophylactically in 127 cases (32%) of planned extended

83 that adenoviral vectors can be administered prophylactically in acute inflammatory syndromes, and ex

84 her approach is performing SVCI in all cases prophylactically in addition to PVI.

85 icacy of the colony-stimulating factors used prophylactically in both solid tumors and the hematologi

86 ng the optimal antibiotic drug to be applied prophylactically in clinical situations in which the epi

87 and gastric devascularization were performed prophylactically in one patient with a history of varice

88 in reducing occurrence of delirium when used prophylactically in patients undergoing elective surgery

89 plasminogen activator [tPA]) cannot be used prophylactically in this high-risk setting because of th

90 hibited IBV NA sialidase activity, protected prophylactically in vivo, and bound to the lateral corne

91 sion has a strong antiviral effect when used prophylactically, inhibiting the spread of Mo-MLV and re

92 nately, there are no current treatments that prophylactically limit sympathetic hyperreflexia to prev

93 ia, 173 were treated with rVIII-SingleChain, prophylactically (N = 146) or on-demand (N = 27).

94 When SB 242235 was administered to AIA rats prophylactically on days 0-20, it inhibited paw edema at

95 by a MuSK agonist antibody, presented either prophylactically or after disease onset.

96 treatments with an anti-MCH antibody, either prophylactically or after the establishment of colitis,

97 r lymphocyte infusions may also be used both prophylactically or at the time of leukemia relapse.

98 the PPARgamma agonist, pioglitazone, either prophylactically or during inflammation, significantly e

99 el of infection with VacV, whether delivered prophylactically or postinfection, and restricts spread

100 genous administration of RANKL, given either prophylactically or postinjury, reduces liver injury in

101 ns or hyperimmunized animals, have been used prophylactically or therapeutically as countermeasures f

102 These molecules can prophylactically or therapeutically control infection in

103 protective effects in vivo when administered prophylactically or therapeutically in a murine H5N1 cha

104 uced pathological sequelae when administered prophylactically or therapeutically in rhesus macaques.

105 s recombinant interleukin-12 (rIL-12) either prophylactically or therapeutically provides significant

106 antimicrobial responses and that they can be prophylactically or therapeutically targeted to protect

107 ar factor kappa B (NF-kappa B) p65 was given prophylactically or therapeutically to block chronic inf

108 Immunoregulatory interventions that act prophylactically or therapeutically to induce antigen-sp

109 s antibody is protective if delivered either prophylactically or therapeutically to mice infected wit

110 S. aureus lung infections, when administered prophylactically or therapeutically, either as monothera

111 molecule once daily for up to six weeks acts prophylactically or therapeutically, in a dose-dependent

112 ate that strongly neutralizing mAbs protect, prophylactically or therapeutically, in animal models.

113 e transfer of MTOR complementary DNA, either prophylactically or therapeutically, mitigated inflammat

114 Preclinical study: REGN3048 plus REGN3051, prophylactically or therapeutically, was substantially m

115 portantly, oral verdinexor treatments, given prophylactically or therapeutically, were efficacious in

116 s were observed when the antagonist was used prophylactically or therapeutically, with comparable eff

117 s, and prevented mortality, when used either prophylactically or therapeutically.

118 ne encephalomyelitis (EAE) when administered prophylactically or therapeutically.

119 rom lethal CCHFV challenge when administered prophylactically or therapeutically.

120 daily with vehicle alone or BI-BTK-1, either prophylactically or therapeutically.

121 dimethyl sulfoxide) was administered either prophylactically or therapeutically.

122 was administered orally twice daily, either prophylactically or therapeutically.

123 ccharide and peptidoglycan when given either prophylactically or therapeutically.

124 stration (4.5 mg/kg/hr intravenously) either prophylactically or therapeutically.

125 Used prophylactically, oral zinc is associated with a reduced

126 in and amoxicillin-clavulanate, administered prophylactically over a period of 28 days after a lethal

127 cell survival(7,8), and infused these cells prophylactically post-HCT into 12 patients ( NCT01640301

128 A combination of two MAbs given prophylactically prior to and 12 h following oocyst chal

129 LEX(-) ) and steroids administration timing (prophylactically [proST] or therapeutically [therST]) on

130 Furthermore, guinea pigs and mice were prophylactically protected from genital challenge with h

131 sarbecovirus clades to a cryptic epitope and prophylactically protects hamsters from viral challenge.

132 decades, anesthesiologists and surgeons have prophylactically provided 'stress steroids' to patients

133 having penicillin allergy are less likely to prophylactically receive cefazolin and more likely to re

134 lly providing an opportunity to identify and prophylactically replace failure-prone valves.

135 Prophylactically resecting the contralateral tonsil may

136 A neutralizing anti-human IL-21 mAb given prophylactically significantly reduced GVHD-associated w

137 imes the drug's EC50 when treatment is given prophylactically starting at the time of infection.

138 mer's disease will likely be more successful prophylactically than therapeutically.

139 reover, when used collectively and delivered prophylactically, the 10-ISG collection was able to prot

140 Prophylactically, the vaccine was highly effective at pr

141 When SB 273005 was administered prophylactically to AIA rats twice per day, it inhibited

142 also have the ability to act palliatively or prophylactically to alleviate levodopa-induced response

143 Radiation delivered prophylactically to asymptomatic, high-risk bone metasta

144 s effective as ischemic PC and could be used prophylactically to attenuate ischemia in selected patie

145 ischemic preconditioning) and could be used prophylactically to attenuate ischemia in selected patie

146 as an antipathogenic agent that can be used prophylactically to block furin-dependent cell killing b

147 ted against the F glycoprotein, administered prophylactically to children at very high risk of severe

148 When 80R IgG1 was given prophylactically to mice at doses therapeutically achiev

149 and mitigated weight loss when administered prophylactically to mice susceptible to SARS-CoV-2, indi

150 IV allopurinol, administered prophylactically to patients at high risk of developing

151 n of acute ischemic complications when given prophylactically to patients during high risk PTCA.

152 While several MAbs functioned prophylactically to prevent DENV-3-induced lethality in

153 ns, including oral tolerance, have been used prophylactically to prevent development of acute EAE as

154 orms of Ag-specific tolerance have been used prophylactically to prevent development of acute EAE.

155 This approach can be applied either prophylactically to prevent invasion of nontyphoidal Sal

156 est that a monoclonal antibody could be used prophylactically to prevent lower respiratory tract dise

157 landins, and tranexamic acid, have been used prophylactically to prevent postpartum haemorrhage.

158 actor or treated plasma derived factor given prophylactically to prevent spontaneous bleeding are rec

159 suggest that NMDA receptor blockade may act prophylactically to prevent the appearance of motor resp

160 can either mitigate cholera symptoms, or act prophylactically to prevent the virulent effects of a ch

161 improved therapeutic agents that can be used prophylactically to provide effective hemostasis.

162 commends that platelets should be transfused prophylactically to reduce the risk for spontaneous blee

163 Drugs targeting host proteins can act prophylactically to reduce viral burden early in disease

164 LIMM102 was administered prophylactically to wild-type mice subjected to IRI-indu

165 It has also been given prophylactically to women with a strong family history o

166 ents may be used therapeutically, as well as prophylactically, to alleviate allergen- induced inflamm

167 eficial in treating established PF and also, prophylactically, to reduce the risk for PF after DP.

168 Importantly, D5R-deficient DCs prophylactically transferred into wild-type recipients w

169 .09%-10.48%; I(2) = 0.0%), and 15 studies of prophylactically treated eyes showed an incidence of 5.1

170 were delayed and somewhat suppressed in the prophylactically treated groups, but mice were protected

171 Twelve studies of prophylactically treated individuals showed an RRD incid

172 a/beta T cell-depleted bone marrow cells and prophylactically treated the MCMs with cyclophosphamide

173 ed in paclitaxel-treated mice that were only prophylactically treated with a vehicle injection.

174 BALB/c mice were prophylactically treated with antibody prior to RSV infe

175 Rats prophylactically treated with CP8 s.c. were protected ag

176 Previous studies have shown that mice prophylactically treated with PS nanoparticles- either d

177 We show that mice prophylactically treated with siRNA-P to decrease but no

178 tected against infection if the animals were prophylactically treated with type III IFN.

179 ss the potential benefit of prescreening and prophylactically treating heterotaxy patients for CD.

180 that laser photocoagulation may be useful in prophylactically treating radiation retinopathy.

181 me that could prove to be therapeutically or prophylactically useful due to its high catalytic rate a

182 Intravitreal antibiotics were administered prophylactically; vitreous cultures were negative.

183 trast, survival mediated by SKT05 when given prophylactically was independent of Fc effector function

184 eralocorticoids are only beneficial if given prophylactically, whereas glucocorticoids are most benef

185 ld be therapeutically relevant, mice treated prophylactically with a blocking CD30L antibody were pro

186 HPA-1a- female mice treated prophylactically with anti-HPA-1a antibody prior to expo

187 IL-10 knockout and normal mice treated prophylactically with anti-IL-10R demonstrated accelerat

188 FL93-939-infected C57BL/6 mice were treated prophylactically with BDGR-49 at 50 mg kg(-1) per day.

189 ol treated mice, NTS-challenged mice treated prophylactically with BI-BTK-1 exhibited significantly a

190 A subgroup treated prophylactically with cefuroxime demonstrated that SAP a

191 However, 80% of these mice treated prophylactically with IL-12 survived compared with 0% su