ライフサイエンスコーパス: propyne

1 reaction between cyclopentene and 1-phenyl-1-propyne.

2 lene, carbon dioxide, and 3-bromo-1-phenyl-1-propyne.

3 tion of C(6)H(5)NH(2) and C(6)D(5)NH(2) with propyne.

4 on C(3) hydrocarbons: propane, propene, and propyne.

5 addition (X = Br, Cl, F) to alkynes (ethyne, propyne, 2-butyne, trifluoromethylethyne, trimethylsilyl

6 The hydroxyl propyne (48) and butyne (23) were among the most potent

7 7-Propyne-7-deaza-2'-deoxyguanosine is a promising lead an

8 s with three and four substitutions of the 7-propyne-7-deaza-2-amino-2'-deoxyadenosine exhibited a 2-

9 With propyne, a competing cyclotrimerization deactivation pro

10 dihydrophthalazine-1,4-dione with 1-phenyl-1-propyne afforded a monoalkenylated product.

11 on turns out to be selective with respect to propyne-allene rearrangements.

12 The 7-propyne and 7-iodo nucleosides were incorporated into an

13 th the model reaction of acetone addition to propyne and allene, the addition of acetone and acetophe

14 ability and remarkably high uptakes for both propyne and propadiene at low pressures.

15 Simultaneous removal of trace amounts of propyne and propadiene from propylene is an important bu

16 Moreover, we were able to visualize propyne and propadiene molecules in the single-crystal s

17 ttributed to its strong binding affinity for propyne and propadiene over propylene.

18 nderstand the binding sites and affinity for propyne and propadiene.

19 d in the hydrogenation products of 1-butene, propyne, and 1-butyne.

20 ese data suggest the formation of 1-phenyl-1-propyne (C(6)H(5)CCCH(3)) via the barrierless addition o

21 ers synthesized by their click reaction with propyne carboxyfluorescein are seen to accumulate around

22 identified include acetaldehyde (CH(3)CHO), propyne (CH(3)CCH), propene (CH(2)CHCH(3)), and water (H

23 ed structure of cyclotetrabenzoin transports propyne chiefly through pore enlargement.

24 BrCH2Cl, CH3CH2OH, CH3CN, CH3NO2, I2), and a propyne clathrate (CH3CCH@Me,H,SiMe2.2CHCl3), have been

25 C or G of a CpG dinucleotide with 5-OH-dC, 5-propyne-dC, furano-dT, 1-(2'-deoxy-beta- d-ribofuranosyl

26 synthesis of 1,3-disubstituted allenes, the propyne derivatives containing either a allyl(tert-butyl

27 analysis point to the unique ability of C-5 propyne dU ODNs to selectively bind to RNA within cells

28 C-5 propyne dU phosphorothioate ODNs bind selectively and wi

29 netics-achieves dynamic binary separation of propyne from propylene under ambient conditions and vari

30 The incorporation of the propyne group at the 5 position gives rise to a very lar

31 In the propynylated duplexes, the propyne group stacks on the aromatic ring of the 5'-base

32 pplications, like the production of MMA from propyne, hydroesterification seems to have an advantage

33 inking acetylene moiety was confirmed, and a propyne link was preferred over a butyne link.

34 '-deoxyuridine or 2'-deoxycytidine through a propyne linker.

35 The preferred propyne location in HOF has also been identified by SCXR

36 s in a fully solvated system showed that the propyne modification leads to substantial conformational

37 the potency, specificity, and utility of C-5 propyne modified antisense ONs as biological tools and i

38 The increased NMR spectral dispersion of the propyne-modified duplex allowed a larger number of exper

39 To investigate effects of the propyne nucleotide on triplex structure and the factors

40 hile both materials exhibit a preference for propyne, only the tetraacetate-owing to its higher surfa

41 We demonstrate that C-5 propyne ONs as short as 11 bases retained 66% of the pot

42 ly inactivated the antisense ON and that C-5 propyne ONs have a biologically active half-life in tiss

43 ver 20-fold, we show that the potency of C-5 propyne ONs is unaffected by changes in the expression l

44 sphorothioate-modified oligonucleotides (C-5 propyne ONs), we have utilized a HeLa line that stably e

45 e targeted with equivalent potency using C-5 propyne ONs.

46 )P(t)Bu(2)) with H(2) and propene, 1-butene, propyne, or 1-butyne are explored by gas-phase nuclear m

47 Selective semi-hydrogenation of propyne over ceria nanocubes yields hyperpolarized prope

48 observed in the hydrogenation of propene and propyne over ceria nanocubes, nano-octahedra, and nanoro

49 HOF-30a enables the selective adsorption of propyne over propylene according to single-component sor

50 restingly, NKPOC-1-alpha selectively adsorbs propyne over propylene and propane under ambient conditi

51 C5-propyne phosphodiester and phosphorothioate compounds we

52 The oligomers contained C-5-propyne (prC), 2'-O-methyl (2'-O-Me) or 2'-OH (RNA) grou

53 Selective separation of propyne/propadiene mixture to obtain pure propadiene (al

54 -efficient physisorptive approach to achieve propyne/propadiene separation using microporous metal-or

55 NKMOF-1-M separated a ternary propyne/propadiene/propylene (0.5 : 0.5 : 99.0) mixture

56 Adsorptive separation of propyne/propylene (C(3)H(4)/C(3)H(6)) is a crucial yet c

57 efficient separations of acetylene/ethylene, propyne/propylene, and butyne/1,3-butadiene mixtures, wi

58 xazine bases into a previously optimized C-5 propyne pyrimidine modified 7-mer phosphorothioate oligo

59 We evaluate C-5 propyne pyrimidine modified phosphorothioate antisense o

60 of short (7 and 8 nt) ONs modified with C-5 propyne pyrimidines and phosphorothioate internucleotide

61 The high propyne selectivity and separation trends were explained

62 nels by ~19 degrees allows adjustment to the propyne structure, maximizing interactions with the C=C

63 extracts by the mechanism-based inactivator propyne, suggesting that it is the catalytic component a

64 hat facilitates the capture and transport of propyne through the crystal.

65 Cu nanoparticles semihydrogenate 1-phenyl-1-propyne to cis-beta-methylstyrene (20 bar H2, 40 degrees

66 couplings of primary alcohols with 1-aryl-1-propynes to form products of carbonyl anti-(a-aryl)allyl

67 Removing a single propyne two base pairs away from a mismatch in a PrODN:R

68 Highly tractable 1-aryl-1-propynes, which are readily accessible via Sonogashira c

69 common features, it was weakly inhibited by propyne with an apparent Km value of 340 microM.

70 The hydroesterification of propyne with their Pd(OAc)2/PN/HA (PN = (2-pyridyl)diphe