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1 peT(H)2 but not cT(H)2 cells produced prostaglandin D2.
2 vage fluid (BALF) contain elevated levels of prostaglandin D2.
3 alpha, prostaglandin I2, thromboxane A2, and prostaglandin D2.
4 ase of the mast cell mediators histamine and prostaglandin D2.
5 pase D, which can increase the production of prostaglandin D2.
6 erbation was associated with reduced exudate prostaglandin D2 and 15deoxy delta(12-14)prostaglandin J
7 ng, resulting in the synthesis of 15R-methyl prostaglandin D2 and allows rapid access to other prosta
8 results from GPR109A-mediated production of prostaglandin D2 and E2 in Langerhans' cells which act o
10 tamine, cysteinyl-leukotrienes, prostanoids (prostaglandin D2 and prostaglandin E2), and interleukin-
11 T cells highly express Cox-2 and synthesize prostaglandin D2 and related prostaglandins that are PPA
12 nd release of arachidonate, the precursor of prostaglandin D2 and the vasodilator responsible for the
13 r prostanoids: prostacyclin, thromboxane A2, prostaglandin D2, and 12-hydroxyheptadecatrienoic acid.
16 ls, along with increased production of IL-5, prostaglandin D2, and eosinophil and T-helper type 2 cel
18 ors (histamine, serotonin, leukotriene C(4), prostaglandin D2, and mouse mast cell protease 1) were q
20 tabolites of prostacyclin, prostaglandin E2, prostaglandin D2, and thromboxane A2 were also reduced.
21 id pathway modifiers on the horizon, such as prostaglandin D2 antagonists and cannabinoids, with eico
22 ocation, showing increases in metabolites of prostaglandin D2, cysteinyl leukotrienes, and isoprostan
25 on pathways mediating the anti-lipolytic and prostaglandin D2/flushing pathways are distinct and that
28 er than twice the upper limit of normal) and prostaglandin D2 (>3.4 times the upper limit of normal)
32 been previously reported that in addition to prostaglandin D2, mast cells produce other eicosanoids,
36 urring compounds such as fatty acids and the prostaglandin D2 metabolite 15-deoxy-delta prostaglandin
37 strogen treatment induced the formation of a prostaglandin D2 metabolite that activated duck PPARgamm
38 suggest that PPAR-gamma and locally produced prostaglandin D2 metabolites are involved in the regulat
40 selective DP2 agonist 13, 14-dihydro-15-keto prostaglandin D2 on epithelial cell migration and differ
43 at Ptgds encodes the enzyme that synthesizes prostaglandin D2 (PGD(2)), we further explored its role
51 ks provide evidence of the importance of the prostaglandin D2 (PGD2) metabolic pathway in inflammator
52 n-type prostaglandin D synthase (L-PGDS) and prostaglandin D2 (PGD2) metabolites produced by normal p
55 Here, we show that mice deficient in the prostaglandin D2 (PGD2) receptor CRTH2 and mice with CRT
56 We show in this paper that lipocalin-type prostaglandin D2 (PGD2) synthase (L-PGDS) interacts intr
59 motaxis of inflammatory cells in response to prostaglandin D2 (PGD2), is hypothesized to play a role
60 niacin provokes Langerhans cells to produce prostaglandin D2 (PGD2), stimulating vascular DP1 recept
66 mphopoietin [TSLP]) and mast cell mediators (prostaglandin D2 [PGD2]) are critical activators of ILC2
69 amster ovary cells and permits chemokine and prostaglandin D2 production by LAD2 cells, a human mast
72 excretion of the major urinary metabolite of prostaglandin D2 (r = 0.98) and Ntau-methylhistamine (r
73 circulated human CD4+ T cells expressing the prostaglandin D2 receptor (CRTH2) are TH2 central memory
76 that fevipiprant (QAW039), an antagonist of prostaglandin D2 receptor 2, might reduce eosinophilic a
77 histocompatibility complex type II, and the prostaglandin D2 receptor CD294, all normally associated
78 gic rhinitis (SAR) is partly mediated by the prostaglandin D2 receptor chemoattractant receptor homol
80 identified prostaglandin E2 receptor EP2 and prostaglandin D2 receptor DP as responsive to OxPAPC.
82 econd intron of the thromboxane A2 receptor, prostaglandin D2 receptor, prostaglandin I2 receptor, an
83 d, compound 1 (AGN 211377), that antagonizes prostaglandin D2 receptors (DPs) DP1 (49) and DP2 (558),
84 ect the functional consequences of decreased prostaglandin D2 release and the therapeutic benefit of
85 ession, activation, cytokine, histamine, and prostaglandin D2 release, and performed transcriptomics
87 dehydrogenase 2 (RALDH2) and lipocalin-type prostaglandin D2 synthase (LPGDS), which, respectively,
89 g growth factor beta receptor 3 (TGFBR3) and prostaglandin D2 synthase (PTGDS) had the strongest asso
94 matrix metalloproteinase 11, integrin beta2, prostaglandin D2 synthase, and interleukin-1 receptor an
95 tatin A, Charcot-Leydon crystal protein, and prostaglandin D2 synthase, implying their broader roles
99 andin-J2 (delta 12-PG J2) is a derivative of prostaglandin D2 that has been shown to have similar inh