ライフサイエンスコーパス: prostaglandin-endoperoxide synthase

1 n G2 by the cyclooxygenase (COX) activity of prostaglandin endoperoxide synthases.

2 nic acid substrate was also not available to prostaglandin endoperoxide synthase 1 in the immediate p

3 chanisms of damage involve the activities of prostaglandin-endoperoxide synthase 1 (PTGS1 or cyclooxy

4 pithelium and included IL-1 receptor like 1, prostaglandin-endoperoxide synthase 1, CCL26, and perios

5 se domain mutations, but only a single gene, prostaglandin-endoperoxide synthase 1/cyclooxgenase 1 (P

6 r F2-isoprostanes, is a minor product of the prostaglandin endoperoxide synthase-1 (PG G/H S-1) expre

7 m of action of this drug, we expressed human prostaglandin endoperoxide synthase-1 (PGHS-1) and PGHS-

8 nation of the crystal structure of the ovine prostaglandin endoperoxide synthase-1 (PGHS-1)/S- flurbi

9 orted to inhibit arachidonate oxygenation by prostaglandin endoperoxide synthase-1 and -2 (PGHS-1 and

10 nase, ephrin-A receptor 2 (EPHA2), regulates prostaglandin endoperoxide synthase 2 (PTGS2) (encodes C

11 enhanced ovarian expression of PLA(2)G4A and prostaglandin endoperoxide synthase 2 (PTGS2) in wild-ty

12 volves the activation-dependent induction of prostaglandin endoperoxide synthase 2 and the supply of

13 cyclooxygenase 2 (COX-2) gene, also known as prostaglandin-endoperoxide synthase 2 ( PTGS2), occurs i

14 s, such as histamine and proteases, activate prostaglandin-endoperoxide synthase 2 (also called COX2)

15 imental evidence suggests that inhibition of prostaglandin-endoperoxide synthase 2 (PTGS2) (also know

16 teraction) = 0.02) with a genetic variant in prostaglandin-endoperoxide synthase 2 (PTGS2) (rs1204276

17 into the nucleus.Notably, after OT challenge prostaglandin-endoperoxide synthase 2 (PTGS2) expression

18 rowth/differentiation factor 15 (GDF15), and Prostaglandin-endoperoxide synthase 2 (PTGS2) genes, pre

19 Prostaglandin-endoperoxide synthase 2 (PTGS2) is a key r

20 s that constitutively express high levels of prostaglandin-endoperoxide synthase 2 (Ptgs2, also known

21 es a role of RAF kinases in up-regulation of prostaglandin-endoperoxide synthase 2 (PTGS2, cyclooxyge

22 We found that induction of prostaglandin-endoperoxide synthase 2 (Ptgs2/Cox-2) and

23 ionship between levels of MIC1 and levels of prostaglandin-endoperoxide synthase 2 expression (PTGS2

24 ted Myd88(-/-) (TLR signaling-deficient) and prostaglandin-endoperoxide synthase 2(-/-) (Ptgs2(-/-))

25 of transfected A549 cells showed that PTGS2 (prostaglandin-endoperoxide synthase 2) was one of the hi

26 TGS2 (also known as COX2), the gene encoding prostaglandin-endoperoxide synthase 2, allowing activate

27 Alternatively, celecoxib, an inhibitor of prostaglandin-endoperoxide synthase 2, reduced polyp num

28 The gene expressions of prostaglandin-endoperoxide synthase 2, tissue inhibitor

29 al hypoperfusion increases the expression of prostaglandin endoperoxide synthase-2 (PGHS-2) in ovine

30 The prostaglandin endoperoxide synthase-2 (PGS-2) gene encod

31 sly, we have shown that forced expression of prostaglandin endoperoxide synthase-2 [also called cyclo

32 t the cyclooxygenase-2 (COX-2, also known as prostaglandin endoperoxide synthase-2) signaling cascade

33 Site-directed mutants of prostaglandin-endoperoxide synthase-2 (PGHS-2) with chan

34 Levels of prostaglandin E(2) and the prostaglandin-endoperoxide synthase-2 (PTGS2, or COX-2)

35 Prostaglandin-endoperoxide synthase-2 inhibition increas

36 rleukin-8, toll-like receptor 4, cryropyrin, prostaglandin-endoperoxide synthase-2, and heparinase ge

37 din E(2) (PGE(2)) and its processing enzyme, prostaglandin-endoperoxide-synthase-2/ cyclooxygenase-2

38 One common target for these drugs is prostaglandin endoperoxide synthase, also referred to as

39 rved in carcinogenesis, prostaglandins (PG), prostaglandin-endoperoxide synthases, and PG receptors a

40 with its primary mode of action in mammals (prostaglandin-endoperoxide synthases) but modulated gene

41 ase activities of constitutive and inducible prostaglandin endoperoxide synthases by serving as a sub

42 s as a neuroendocrine factor that stimulates prostaglandin-endoperoxide synthase [cyclooxygenase (Cox

43 duction of prostaglandin G/H synthase (PGHS; prostaglandin endoperoxide synthase, cyclooxygenase) by

44 repressed the mRNA and protein expression of prostaglandin endoperoxide synthase/cyclooxygenase-2 (CO

45 Cyclooxygenase (COX), also referred to as prostaglandin endoperoxide synthase, is the rate-limitin

46 Reaction of manganese-reconstituted prostaglandin endoperoxide synthase (Mn-PGHS) with 15-hy

47 thout affecting the levels of NO synthase or prostaglandin endoperoxide synthase or by inhibiting the

48 (PG) D2 through utilization of constitutive prostaglandin endoperoxide synthase (PGHS) -1 and induce

49 dal antiinflammatory agents (NSAIDs) bind to prostaglandin endoperoxide synthase (PGHS) and induce a

50 Prostaglandin endoperoxide synthase (PGHS) is a heme pro

51 Prostaglandin H(2) synthesis by prostaglandin endoperoxide synthase (PGHS) requires the

52 Prostaglandin endoperoxide synthase (PGHS)-2, the induci

53 gh levels of nitric oxide synthase (NOS) and prostaglandin endoperoxide synthase (PGHS).

54 apid as well as time-dependent inhibitors of prostaglandin endoperoxide synthase (PGHS).

55 Ca2+]i) elevation in regulating ET-1-induced prostaglandin endoperoxide synthase, prostaglandin G/H s

56 Prostaglandin endoperoxide synthases (PTGS), commonly re

57 BACKGROUND & AIMS: Prostaglandin-endoperoxide synthase (Ptgs)2 is an enzyme

58 p-regulation of the constitutively expressed prostaglandin endoperoxide synthase, Ptgs1 (Cox-1), a nu

59 umatoid arthritis to inhibit cyclooxygenase (prostaglandin-endoperoxide synthase), thereby decreasing