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1 urine doped with different concentrations of prostate specific antigen.
2 amino acids sequence (HSSKLQL) specific for Prostate Specific Antigen.
3 pairs that are associated with pre-operative prostate-specific antigen.
4 ction and prostate cancer together with KLK3/prostate-specific antigen.
5 on of PSMA PET-derived parameters with serum prostate-specific antigen.
6 te-specific antigen < 10 ng/mL or Gleason 6, prostate-specific antigen, 10 to 20 ng/mL), LDR brachyth
9 ould improve specificity over measurement of prostate-specific antigen alone for detecting cancer wit
10 o biopsy, adjusting for age and longitudinal prostate-specific antigen and digital rectal examination
11 cancer screening currently consists of serum prostate-specific antigen and digital rectal examination
14 o noted a significant decrease in both KLK3 (prostate-specific antigen ) and FOLH1 (prostate-specific
15 variate analysis, controlling for age, serum prostate specific antigen, and abnormal digital rectal e
16 rkers, including human alpha-thrombin, human prostate specific antigen, and human epidermal growth fa
17 performance status, higher testosterone and prostate-specific antigen, and lower hemoglobin than whi
18 lation with progression-free survival (PFS), prostate-specific antigen, and markers of bone turnover.
19 ety; progression-free survival (PFS); tumor, prostate-specific antigen, and pain response; pharmacoki
21 t prostate cancers after the introduction of prostate-specific antigen-based screening are now being
22 d indices and explored their relation to the prostate-specific antigen blood value, the bone scan ind
23 ional imaging and unspecific fluctuations in prostate-specific antigen can hamper early diagnosis of
24 SUVs and lesion number were correlated with prostate-specific antigen change, clinical impression, a
25 ad not had radiotherapy using Gleason score, prostate-specific antigen concentration, surgical margin
26 e and that anti-GRP78 AutoAb levels parallel prostate-specific antigen concentrations in patient-deri
28 acy was biochemical response as defined by a prostate-specific antigen decline >/= 50% from baseline
31 4; P = .030), but not when also adjusted for prostate-specific antigen density (PSAD; HR, 1.85; 95% C
32 cancer cases were categorized by a preceding prostate-specific antigen/digital rectal examination pro
34 , castration-resistant prostate cancer and a prostate-specific antigen doubling time of 10 months or
35 , castration-resistant prostate cancer and a prostate-specific antigen doubling time of up to 10 mont
36 C at high risk for metastatic disease (rapid prostate-specific antigen doubling time or velocity) but
38 were performed in 36 subjects with a rising prostate-specific antigen for known (n = 15) or suspecte
40 the MRI grade model and clinical parameters (prostate-specific antigen, Gleason score) for pathologic
41 r and had received no previous chemotherapy; prostate-specific antigen greater than 5 ng/mL; and a Ka
42 application of this technology in detecting Prostate Specific Antigen in clinically relevant levels
43 tor, aedemonstrated a sustained reduction in prostate-specific antigen in a patient with CRPC, and an
44 We demonstrate femtomolar-level detection of prostate-specific antigen in biological fluids, as well
45 tures plus the MRI-based EPE grading system (prostate-specific antigen, International Society of Urol
47 , or placebo (Arm P; n = 433), stratified by prostate-specific antigen (less than 50 ng/mL v 50 ng/mL
48 Biochemical failure was defined as a serum prostate-specific antigen level > 0.2 ng/mL that increas
49 tectomy and/or radiation therapy with rising prostate-specific antigen level (median, 2.27 ng/mL; ran
50 ing hemoglobin level (r = -0.521, P < .001), prostate-specific antigen level (r = 0.556, P < .001), l
51 ), Gleason score (rho, range, 0.03 to 0.20), prostate-specific antigen level (rho, range, -0.07 to 0.
52 changes in tDV and best percentage change in prostate-specific antigen level and circulating tumor ce
53 st and logistic regression; correlation with prostate-specific antigen level and circulating tumor ce
55 cancer is suspected when an increase in the prostate-specific antigen level is detected after radica
56 tile range [IQR], 61-72) years, median (IQR) prostate-specific antigen level of 43 (18-88) ng/mL.
57 ; they had Gleason scores of 7-10 and a mean prostate-specific antigen level of 7.8 mug/L (range, 5.4
58 e prostate cancer, particularly those with a prostate-specific antigen level of less than 10 ng/mL an
60 66-74 y) with biochemical recurrence (median prostate-specific antigen level, 1.31 ng/mL; interquarti
62 with prostate-specific antigen relapse (mean prostate-specific antigen level, 5 ng/mL; range, 0.25-29
66 ) and metastatic findings were compared with prostate-specific antigen level, International Society o
67 (244/691) and was associated with increasing prostate-specific antigen level, ISUP grade, and clinica
70 ve study of 140 patients with elevated serum prostate specific antigen levels and/or abnormal digital
72 gital rectal examination results or elevated prostate-specific antigen levels (age groups: 41-50 year
73 s, the assay was superior to the analysis of prostate-specific antigen levels (area under the curve:
74 undance of circulating MDSCs correlates with prostate-specific antigen levels and metastasis in patie
75 ed to delineate the relationship between the prostate-specific antigen levels and the diffusion param
76 obtained by applying mathematical models to prostate-specific antigen levels as the representation o
77 stage cT1-2, localized prostate cancer, with prostate-specific antigen levels less than 50 ng/mL, and
78 only (n = 16), after surgery and with serum prostate-specific antigen levels lower than 0.2 ng/mL (n
80 ematologic status, renal function, and serum prostate-specific antigen levels were documented before
84 ntermediate risk prostate cancer (Gleason 7, prostate-specific antigen < 10 ng/mL or Gleason 6, prost
85 n score <= 7, clinical stage T1b to T3a, and prostate-specific antigen < 30 ng/mL were randomly alloc
87 Following detection of high levels of serum prostate-specific antigen, many men are advised to have
89 llowed (ie, biopsy at 12-month intervals and prostate-specific antigen measurement and digital rectal
90 ical failure was defined with the use of the prostate-specific antigen nadir + 2-ng/mL definition), f
91 herapy) was 1% +/- 40%, excluding 1 patient (prostate-specific antigen-negative) from the population.
92 hanges occurred most often for patients with prostate-specific antigen of 0.5 to less than 2.0 ng/mL
94 associations included the following: SUV and prostate-specific antigen percentage change at 6 mo (P =
95 risk factors common across the trials (age, prostate-specific antigen, performance status, alkaline
97 nts in all key secondary end points: time to prostate-specific antigen progression (HR, 0.19; 95% CI,
101 rogen receptor and its target gene products, prostate specific antigen (PSA) and ETS-related gene (ER
102 range) was decorated with antibodies against prostate specific antigen (PSA) and prostate specific me
103 ing 8-hydroxy-2'-deoxyguanosine (8-OHdG) and prostate specific antigen (PSA) as representatives for s
104 ta-MIP) with FETs for sensitive detection of prostate specific antigen (PSA) at clinically relevant c
105 urement of prostate volume, uroflowmetry and prostate specific antigen (PSA) at one, 3 and 6 months a
106 was designed to utilize for the detection of prostate specific antigen (PSA) based on three different
107 s method, post-prostatectomy surveillance of prostate specific antigen (PSA) can be achieved with a d
108 n in human serum of as low as 25 pg/ml total prostate specific antigen (PSA) during 30-min assay.
110 exhibited real-time reversible detection of prostate specific antigen (PSA) from 1 to 1,000 nM in 10
111 trated label-free and real-time detection of prostate specific antigen (PSA) in human serum using sil
117 Highly sensitive and label free detection of prostate specific antigen (PSA) still remains a challeng
120 States Food and Drug Administration) is the prostate specific antigen (PSA) that is detected by conv
121 unting single molecules of the cancer marker prostate specific antigen (PSA) using photon-upconversio
122 detection of recurrent disease at low serum prostate specific antigen (PSA) values below 0.5 ng/mL c
123 ed DNA aptamer with established affinity for prostate specific antigen (PSA) was complexed with PSA p
126 ances were implemented for glycoprofiling of prostate specific antigen (PSA), what can be applied for
127 de (rGO) thin films as transducers to detect prostate specific antigens (PSA) in a physiological buff
128 tal of 819 patients staged: (1) cT1b-c, with prostate-specific antigen (PSA) >/= 10 ng/mL or Gleason
132 e radiotherapy (SRT) for men with detectable prostate-specific antigen (PSA) after radical prostatect
134 on the therapeutic response as determined by prostate-specific antigen (PSA) and alkaline phosphatase
136 ncluding high Gleason score, clinical stage, prostate-specific antigen (PSA) and extent of disease, a
138 ced prostate MR imaging in men with elevated prostate-specific antigen (PSA) and negative transrectal
139 urpose We evaluated the relationship between prostate-specific antigen (PSA) and overall survival in
140 ing tool, to diagnose prostate cancer (PCa): prostate-specific antigen (PSA) and spondin-2 (SPON2).
141 ndwich immune complexes of the cancer marker prostate-specific antigen (PSA) are detected and counted
144 ent of the gold content allowed detection of Prostate-Specific Antigen (PSA) at the low attog mL(-1)
145 se with biochemical recurrence stratified by prostate-specific antigen (PSA) at the time of imaging.
146 rvation policy with salvage radiotherapy for prostate-specific antigen (PSA) biochemical progression.
147 pplied stratification systems use presenting prostate-specific antigen (PSA) concentration, biopsy Gl
148 r radical prostatectomy in patients with low prostate-specific antigen (PSA) concentrations (<2.0 ng/
149 ease-specific quality of life, health worry, prostate-specific antigen (PSA) concern, and outlook on
152 ith castration-sensitive prostate cancer and prostate-specific antigen (PSA) doubling time (DT) of le
153 The inclusion criterion for this study was a prostate-specific antigen (PSA) doubling time of less th
156 gen) PET/CT is increasingly used in men with prostate-specific antigen (PSA) failure after radical pr
157 controlled trials (RCTs) relating to reduced prostate-specific antigen (PSA) failure, yet whether thi
158 combinations of histopathology, imaging, or prostate-specific antigen (PSA) follow up, defined as co
160 ening and quantitatively precise analysis of prostate-specific antigen (PSA) in 10 min from merely on
162 ascular endothelial growth factor (VEGF) and prostate-specific antigen (PSA) in human serum for early
163 e of nanopore blockade sensing system, where prostate-specific antigen (PSA) is used as a model analy
165 , renal scintigraphy, clinical data, and the prostate-specific antigen (PSA) level at baseline and 8
166 to determine the relationship between serum prostate-specific antigen (PSA) level categories (<5, 5-
167 deprivation therapy (ADT), as reflected by a prostate-specific antigen (PSA) level higher than 4.0 ng
169 e >=70 years), stage cT2a or less, and serum prostate-specific antigen (PSA) level less than 10 ng/mL
170 SMA-targeted radiotracers in patients with a prostate-specific antigen (PSA) level less than 2 ng/mL.
171 rrent prostate cancer in 60% of cases with a prostate-specific antigen (PSA) level of >=0.4 to <0.5,
172 early stage of biochemical recurrence with a prostate-specific antigen (PSA) level of less than 1 ng/
176 ogression-free survival as determined by the prostate-specific antigen (PSA) level, clinical progress
177 ADT, with complete datasets for RT, surgery, prostate-specific antigen (PSA) level, Gleason score, an
178 rior negative biopsy findings with increased prostate-specific antigen (PSA) level, or (c) had a prio
179 med recurrence was correlated with patients' prostate-specific antigen (PSA) level, primary Gleason s
180 fine patient characteristics, including age, prostate-specific antigen (PSA) level, PSA density, race
182 ets in the blood of 72 asymptomatic men with Prostate-Specific Antigen (PSA) levels < 20 ng ml(-1), o
183 olled in an imaging protocol based on rising prostate-specific antigen (PSA) levels (mean, 3.43 ng/mL
184 led onto an imaging protocol based on rising prostate-specific antigen (PSA) levels (mean:3.43 ng/mL,
185 ity rate of 85%, which increased with higher prostate-specific antigen (PSA) levels (ng/mL): 50% (PSA
186 Positive scan results (P < 0.001) and higher prostate-specific antigen (PSA) levels (P = 0.024) were
187 (68)Ga-PSMA I&T PET/CT because of increasing prostate-specific antigen (PSA) levels after radical pro
188 A significant proportion of men with rising prostate-specific antigen (PSA) levels after radical pro
189 interrogated irrespective of Gleason grade, prostate-specific antigen (PSA) levels and pathological
190 Joint statistical model of longitudinal prostate-specific antigen (PSA) levels and risks for bio
192 identify genes associated with pre-operative prostate-specific antigen (PSA) levels in patients.
193 ay with biopsy outcomes in 499 patients with prostate-specific antigen (PSA) levels of 2 to 20 ng/mL.
194 ty-one patients with postprostatectomy serum prostate-specific antigen (PSA) levels of at least 0.2 n
195 stant prostate cancer and rapidly increasing prostate-specific antigen (PSA) levels while taking andr
197 Criteria in Solid Tumors 1.1), a decrease in prostate-specific antigen (PSA) of 50% or more (PSA50) f
198 One hundred eighteen patients with a median prostate-specific antigen (PSA) of 6.4 ng/mL (range, 2.2
199 ET lesions in a selected patient cohort with prostate-specific antigen (PSA) persistence after salvag
200 ry definitive radiotherapy, 51% (88/172) for prostate-specific antigen (PSA) persistence, and 36% (62
201 e (PET1), week 13 (PET2), and at the time of prostate-specific antigen (PSA) progression, standard ra
203 ent continued until radiologic, clinical, or prostate-specific antigen (PSA) progression; otherwise,
204 combination strongly associates with reduced prostate-specific antigen (PSA) recurrence-free survival
205 w and by investigators) and locally assessed prostate-specific antigen (PSA) response (>= 50% decreas
208 ta, week 13 circulating tumor cell (CTC) and prostate-specific antigen (PSA) response end points in f
211 , 2.8-3.7 GBq); afterward, safety lab tests, prostate-specific antigen (PSA) response, and clinical f
213 R-V7-negative disease associated with better prostate-specific antigen (PSA) responses (100% vs. 54%,
215 progression on enzalutamide with a continued prostate-specific antigen (PSA) rise after enzalutamide
216 2012, US guidelines have recommended against prostate-specific antigen (PSA) screening for prostate c
219 sk stratification to identify those for whom prostate-specific antigen (PSA) testing is likely to be
220 ents for prostate cancer that is detected by prostate-specific antigen (PSA) testing remains uncertai
221 -negative patients with a detectable post-RP prostate-specific antigen (PSA) treated with SRT with or
224 uperior to standard-of-care imaging at serum prostate-specific antigen (PSA) values low enough to aff
225 Afterward, data were compared with current prostate-specific antigen (PSA) values, Gleason score (G
232 urinary flow rate, postvoid residual volume, prostate-specific antigen (PSA), and prostate volume wer
233 g tumor cells (CTCs), bone biomarkers, serum prostate-specific antigen (PSA), and symptomatic skeleta
234 cer in patients with renewed increase in the prostate-specific antigen (PSA), commonly referred to as
235 rker for prostate adenocarcinoma (PC), serum prostate-specific antigen (PSA), greatly overestimates P
236 ival outcomes was constructed combining age, prostate-specific antigen (PSA), histological grade, bio
237 he transcription of AR target genes, such as prostate-specific antigen (PSA), is also lowered in the
238 er scheduled for PSMA RLT were evaluated for prostate-specific antigen (PSA), lactate dehydrogenase (
240 supports individualised decision-making for prostate-specific antigen (PSA)-based screening in men a
248 ere evaluable for the primary end point of a prostate-specific antigen (PSA)50 response (PSA decline
249 r growth can be estimated by measuring serum prostate-specific antigen (PSA, a PCa biomarker in blood
250 evidence of either biochemical progression (prostate-specific antigen [PSA] >=0.4 ng/mL and rising a
251 orable-risk (clinical stage cT1 to cT2bN0M0, prostate-specific antigen [PSA] <=20 ng/mL, and Grade Gr
252 e cancer (T1 to 2a, Gleason score </= 6, and prostate-specific antigen [PSA] 10.1 to 20 ng/mL; T2b to
253 e the performance of 4 candidate surrogates (prostate-specific antigen [PSA] failure, PSA nadir >0.5
254 tence (BCP; that is, persistently measurable prostate-specific antigen [PSA] values after robot-assis
255 ) (clinical stage, T1c; Gleason score, </=6; prostate-specific antigen [PSA], <10 ng/mL; PSA density
256 , low- to intermediate-risk prostate cancer (prostate-specific antigen [PSA], <=15 ng/mL; Gleason sco
257 th documented biochemical recurrence (median prostate-specific antigen [PSA], 2.5 ng/mL; range, 0.21-
259 tients (mean age, 68 y; range, 44-87 y) with prostate-specific antigen relapse (mean prostate-specifi
260 cause screening for prostate cancer based on prostate-specific antigen remains controversial due to t
261 .001); proportion of patients with a >/= 50% prostate-specific antigen response (81% v 31%; P < .001)
264 ath, 0.52; 95% CI, 0.40 to 0.68; P<0.001), a prostate-specific antigen response occurred in 35.7% and
265 reasonable response, mainly as defined by a prostate-specific antigen response of more than 50%, com
269 d increases in progression-free survival and prostate-specific antigen response rates suggest antitum
271 checked every 2 wk by laboratory tests, the prostate-specific antigen response was checked every 4 w
272 ith AR-V7-positive mCRPC had fewer confirmed prostate-specific antigen responses (0% to 11%) or soft
280 nding on presentation of symptoms, including prostate-specific antigen, serum creatinine, urine cytol
281 KLK3, the AR-responsive gene that encodes prostate specific antigen, shows the greatest variabilit
282 hemical response, whereas patient 1 achieved prostate-specific antigen stabilization after 3 therapy
284 Active surveillance protocols should include prostate-specific antigen testing, digital rectal examin
285 n of DIO2 was shown to supress expression of prostate specific antigen, the cardinal clinical biomark
286 and were inversely correlated with levels of prostate-specific antigen, the main prognostic factor in
287 onal level) and tumor characteristics (serum prostate-specific antigen, tumor grade and clinical stag
288 s, 11 (18%) demonstrated a >= 50% decline in prostate-specific antigen; two (6%) of 36 with measurabl
290 ficant correlations were found between serum prostate-specific antigen value and both PSMA-TV (r = 0.
293 61 patients with prostate cancer BCR (median prostate-specific antigen value, 1.7 ng/mL; range, 0.05-
295 0.76 and 0.74, respectively, P < 0.001) and prostate-specific antigen values (r = 0.57 and 0.54, res
296 nts who had undergone PSMA PET for CRPC, had prostate-specific antigen values of at least 1 ng/mL, an
298 ously treated with local therapy, and median prostate-specific antigen was 65 ng/mL (IQR 23-184).
299 in this Perspective explore the detection of prostate-specific antigen which enables a comparison bet
300 ode signal outputs, the PT-Disk can quantify prostate specific antigen with limits of detection of 1.