ライフサイエンスコーパス: protect

1 clear ubiquitinated proteins and are cardio-protected.

2 may indicate the presence of a mechanism to protect 3D genome structure integrity during DNA damage

3 ot be displaced by detergent from the highly protected active site.

4 We found that limiting exogenous glutamine protects actively dividing amastigotes from ergosterol b

5 vent the accumulation of too much fat and to protect adults against obesity.

6 also tested whether TRV130 maintenance would protect against acute oxycodone-induced decreases in nuc

7 hibition of RAGE but not TLR4 signalling may protect against airway neutrophilia and AHR in COPD.

8 roteins, including HMGI-C, which is known to protect against apoptosis.

9 esis of glutathione, an antioxidant that may protect against As-induced oxidative stress.

10 e identification of chromosome 21 genes that protect against cancer when overexpressed.

11 ockade of IL-18 receptor in the brain helped protect against cerebrovascular dysfunction despite prol

12 dence also suggests that flavanol-rich diets protect against cognitive aging, but mechanisms remain e

13 es are now being tested for their ability to protect against COVID-19, the authors also comment on th

14 s based on bioactive ingredients in order to protect against diseases and to develop healthy diets.

15 rehensive Fatigue Risk Management Systems to protect against fatigue in nurses, midwives, and other s

16 us, the glycan cap of GP1 may allosterically protect against inactivation of EBOV by premature trigge

17 Nanotube transfer of GNLY allows dNK to protect against infection while leaving the maternal-fet

18 : how host-microbiota metabolic partnerships protect against infection; competition for glucose betwe

19 nt protein-based vaccine that is licensed to protect against invasive group B meningococcal disease.

20 activity, neutralize the virus in vitro, and protect against lethal IBV infection in mice in prophyla

21 te to growing evidence that suggests BCG may protect against M. tuberculosis infection as well as dis

22 3 receipt increased antibody levels that may protect against mumps virus infection for longer than pr

23 signaling in myeloid cells was sufficient to protect against nephritis.

24 tion of mitochondrial oxidative capacity may protect against oxidative stress associated with birth w

25 sing safe adjuvant platform that can help to protect against pandemics and future infectious threats.

26 fusion, pave the way for immunogen design to protect against pathogenic hantaviruses.

27 s up-regulated in response to cell stress to protect against pathological cell death in multiple dise

28 and we would hypothesize that it may act to protect against prolonged placental hypoxia seen in pree

29 oteostasis may hold therapeutic potential to protect against protein aggregation-associated cellular

30 deficits, revert autistic-like behaviors and protect against seizures.

31 Dorsal root ganglia nociceptors protect against STm colonization, invasion, and dissemin

32 Enhancing stress resilience could protect against stress-induced psychiatric disorders in

33 d preventive therapy (IPT) is widely used to protect against tuberculosis (TB) in people living with

34 the fly's auditory neurons accelerated - or protected against - ARHL.

35 ation with both vaccines prevented fever and protected against abortion.

36 Extracellular purines, adenosine and ATP, protected against ALI induced by purified LPS.

37 l inhibition of the MNK-eIF4E signaling axis protected against and reversed spontaneous pain and PNI-

38 ent in preimmunized mice, although they were protected against associated disease.

39 non-B6-derived region of chromosome 11 that protected against B6.Y (POS) sex reversal.

40 hydrosalpinx formation, vaccinated mice were protected against challenges with serovars D (UW-3/Cx),

41 the most favorable genetic background may be protected against CKD.

42 ted viral replication in the lungs, but both protected against clinical disease.

43 hylaxis in these mice and also significantly protected against death during severe anaphylaxis.

44 ous administration of butyrate or propionate protected against hepatic IR injury in intestinal TLR9 d

45 pporting this, P2X4-deficient (KO) mice were protected against ischemic AKI with significantly attenu

46 erent states in an oscillator encode a qubit protected against phase-flip errors(1,2).

47 Likewise, Keap1(f/f) pups were protected against prolonged (96 h) hyperoxia-induced hyp

48 Moreover, the A-allele homozygotes were protected against stress-induced decreases in AEA and ne

49 ays a dual regulatory role in macrophages by protecting against ER stress and promoting anti-inflamma

50 viable therapeutic approach for selectively protecting against the pathologic actions of Abeta in AD

51 de some clues to understanding how melatonin protects against Abeta, and that choice of chain perdeut

52 CR and Cyquant assay, we showed that miR-124 protects against As-induced cytotoxicity in neural cells

53 , where diversifying an investment portfolio protects against economic uncertainty.

54 Our results suggest that m(6)A modification protects against endogenous dsRNA formation and a delete

55 nd human cancer cells, ether-lipid synthesis protects against ferroptosis.

56 Consequently, TEC-derived LXRalphabeta protects against homeostatic premature involution and or

57 acologic activation of the PPARgamma pathway protects against hypoxia-associated IUGR, we used an exp

58 significantly ameliorates glucose tolerance, protects against insulin-resistance onset and remarkably

59 s study was performed to investigate if UDCA protects against ischaemia-induced and reperfusion-induc

60 moral and cell-mediated immune responses and protects against lung infection, inflammation, and patho

61 thionine restriction, a dietary regimen that protects against metabolic diseases and aging, represses

62 antibodies into the neonatal circulation and protects against nHSV neurological sequela and mortality

63 s bacterial infection, promotes healing, and protects against reinfection.

64 oV-2 as well as CD8(+) T cell responses, and protects against SARS-CoV-2 infection in the lungs and n

65 activity of neuronal and lymphoid CB(2)that protects against spontaneous and evoked neuropathic pain

66 Breastfeeding modulates infant growth and protects against the development of obesity.

67 APOL1 protects against trypanosome infections by forming ion c

68 uggest that APP is a restriction factor that protects against ZIKV by serving as a decoy receptor, an

69 ,3-oxazoles containing a variety of sulfonyl-protected alkylamino groups in the fifth position of the

70 expanding the existing global MPA network to protect an additional 5% of the ocean could increase fut

71 , but requires excess quantities of suitably protected and activated building blocks.

72 are actively stalled, remodelled, processed, protected and restarted in response to specific types of

73 4 degrees C, with similar levels of risk in protected and unprotected areas.

74 ction, while DWB exerted a prebiotic effect, protecting and enhancing the viability of L. paracasei.

75 the presence of CD4+ T cells that surround, protect, and promote survival of tumor cells.

76 More importantly, these immunogens protected animals from lethal challenge with both the Af

77 Only after a delay of around 4 months, protecting antibodies against the short L1 appeared, ena

78 virus-neutralizing antibodies are likely to protect, antibodies could potentially trigger immunopath

79 as and ongoing efforts to establish a Marine Protected Area along the Peninsula, a key fishing region

80 Here we test the consequences of different protected area configurations using multi-trophic level

81 t which have been neglected in the design of protected area networks in the tropics, merit increased

82 While China's protected area system still has much room for improvemen

83 Protected areas (PAs) are the cornerstones of global bio

84 exceptional camera-trap dataset spanning 32 protected areas across southern Africa, we find that int

85 of 89%-99% of protected areas, while >95% of protected areas are environmentally suitable for establi

86 We find that <10% of protected areas are home to any of the alien animals, bu

87 Here we show how the expansion of protected areas by national governments since 2010 has h

88 Protected areas form the backbone of biodiversity conser

89 Protected areas have been the cornerstone for conservati

90 servation(1,2), given the shrinking scope of protected areas in many regions.

91 We analyzed protected areas in the continental USA to assess the ext

92 We show that in 80% of ecoregions, protected areas offer equal (25%) or worse (55%) protect

93 Two of the largest protected areas on earth are U.S. National Monuments in

94 rs in many locations have established marine protected areas or seasonal closures to recover these ov

95 hotspots examined this benefit is driven by protected areas preventing both forest loss and degradat

96 n for different periods, and distribution of protected areas, to determine conservation hotspots for

97 in 10-100 km of the boundaries of 89%-99% of protected areas, while >95% of protected areas are envir

98 Droplets protect bound proteins from proteases, and these interac

99 Quadrupole topological phases, exhibiting protected boundary states that are themselves topologica

100 of dynamic self-assemblies of topologically protected but highly deformable particle-like solitons.

101 The double degeneracy of the Dirac bands is protected by a combination of inversion, time-reversal,

102 Bacteria are protected by a polymer of peptidoglycan that serves as a

103 This article is protected by copyright.

104 ning the full classification of bosonic TCSs protected by several onsite symmetry groups and each of

105 ge DNA-binding surface on FACT appears to be protected by the carboxy-terminal domains of both of its

106 mice chronically infected with CL13 could be protected by vaccination with a highly attenuated varian

107 In a screen for mutations protecting C. elegans from hypoxic stress, we isolated m

108 of a fluorenylmethyloxycarbonyl- and trityl-protected, C2-deuterated histidine produces a vibrationa

109 ndance of immune-stimulating bacteria(10,11) protects C9orf72-mutant mice from premature mortality an

110 re environmental conditions physiochemically protect carbon stores from decomposition for thousands o

111 secretory pathway for S. aureus to transport protected cargo in a concentrated form to host cells dur

112 me-associated quality control (RQC) pathways protect cells from toxicity caused by incomplete protein

113 ESR serves two purposes in aneuploid cells: protecting cells from aneuploidy-induced cellular stress

114 AZD1775 induced phosphorylation of DNA-PK, protecting cells from replication-associated DNA damage

115 nerates a metabolic homeostatic circuit that protects cells from bioenergetic crisis and mitochondria

116 SAMHD1 protects cells from invading viruses that depend on dNTP

117 stitute the most crucial defense system that protects cells from therapeutic agents.

118 This could help protect chromosome attachments from transient forces whi

119 zed nucleic acid-protein complexes that help protect chromosome ends from DNA damage.

120 Telomeres protect chromosome ends from inappropriately activating

121 DMCs), or data and safety monitoring boards, protect clinical trial participants by conducting benefi

122 Protecting clinician mental health in the aftermath of c

123 enables the formation of chromatin loops by protecting cohesin against loop release.

124 Seawater from the highly protected 'crown jewel' offshore reefs in Jardines de la

125 d oceans, and informed the creation of fully protected deep-water areas in the Galapagos Marine Reser

126 nd that MLL2 functions in gene expression by protecting developmental genes from repression via repel

127 efficient synthetic route to differentially protected diester, 1-(tert-butyl) 4-methyl (1R,2S,4R)-2-

128 Thus, an effective conservation approach to protect different species is to preserve natural soundsc

129 Protecting ECs from apoptosis in this model did not prev

130 use survival over chemotherapy alone, whilst protecting endogenous HSC.

131 phagic flux may be a therapeutic strategy to protect endothelial function from dyslipidemia and diabe

132 ereocontrol by [3 + 1]-cycloaddition of TIPS-protected enoldiazoacetates with alpha-acyl sulfur ylide

133 us RA metabolism blocking agents, appears to protect epidermal barrier integrity.

134 delivery around five goals: (1) promote and protect equitable access to high-quality cancer care; (2

135 s rapid mobilization of this protein pool to protect exposed ssDNA and repair genomic loci affected b

136 tive neutralizing mAbs, HENV-26 and HENV-32, protected ferrets in lethal models of infection with NiV

137 d a positive effect: canopy greenness within protected forests was more resilient to drought than wit

138 as more resilient to drought than within non-protected forests.

139 nstability, yet the molecular mechanisms for protecting forks from degradation/collapse are not well

140 D (EBAMD) study evaluates serum factors that protect foveal MPOD architecture in Caucasian offspring

141 To protect from aneuploidy, cells possess mechanisms to del

142 high titers of neutralizing antibodies that protect from detectable plasma viremia following rechall

143 not induce gastroparesis per se, nor did it protect from PAN-PDE4 inhibitor-induced gastroparesis, i

144 Boldine has been reported to protect from pathological bone loss during rheumatoid ar

145 this study could potentially be developed to protect from SARS-CoV-2 and some other SARS-like viruses

146 tudies have assumed that decoy-bound TFs are protected from degradation, and in this case decoys func

147 Functionally, TICAM2 deficient mice were protected from developing severe systemic inflammation a

148 de a vacuole in the host cytosol where it is protected from host cytoplasmic innate immune responses.

149 We found that the newly formed memory was protected from interference when it shared a common stru

150 ne, premenopausal women seem to be generally protected from obesity-induced metabolic and cardiovascu

151 ble to two Trypanosoma brucei subspecies but protected from other trypanosomes by circulating high-de

152 ds for a wide range of substrates, reactions protected from overreduction can be performed at high cu

153 (-/-) mice deficient in DC cross-priming are protected from persistent immune-mediated myocardial dam

154 hallenges with SIVmac239, vaccinees were not protected from SIV acquisition but manifested partial co

155 d anatomical viral reservoirs that are often protected from treatment by efflux transporters, such as

156 nate immune pathways capable of promoting or protecting from asthma.

157 responses toward Th1 and Th17 immunity, and protects from allergen challenge after only 2-4 monthly

158 roliferation, enhances DNA end-labeling, and protects from DNA damage, ultimately blocking the proneo

159 ovel role for Nod2 and demonstrate that Nod2 protects from HFD-dependent liver malignancy and this pr

160 during the COVID-19 outbreak is effective in protecting frontline staff from the infection.

161 in T2D, with thoughts on novel strategies to protect functional beta-cell mass.

162 d obesity, as insulin action is preserved to protect fundamental energetic processes in the muscle.

163 Both peptides protected greater than 80% mice from infection-caused de

164 lfonyl moiety, which serves as a base-labile protecting group and confers crystallinity to these cycl

165 reactivity via negative hyperconjugation as protecting group electron withdrawal increases.

166 ation of the tetrafluoropyridyl (TFP) phenol-protecting group.

167 y virtue of changing the nature of the amine protecting group.

168 A low-temperature, protecting-group-free oxidation of 2-substituted aniline

169 ports clinical development of the vaccine to protect groups at risk for contracting the infection.

170 -known as megamolecules-without the need for protecting groups and with precisely defined nanoscale a

171 r protonating agent were examined as well as protecting groups on the xyloside moiety and the influen

172 electron-rich alkenes (glycals) with varied protecting groups to systematically elucidate the factor

173 ty of the conventional amino acid side-chain-protecting groups, t-Bu, Boc, Trt, and Pbf, and the form

174 abortion, supporting the death penalty, and protecting gun rights and you will know.

175 utralizing antibodies (S2E12 and S2M11) that protect hamsters against SARS-CoV-2 challenge.

176 n this retrospective study, 21 categories of protected health information (PHI) in 2503 radiology rep

177 GCs for removal (i.e., a senolytic approach) protected healthy RGCs and preserved visual function in

178 The pulmonary immune response protects healthy individuals against Pneumocystis pneumo

179 s, we tested whether donor-derived MDSCs can protect heart transplant allografts in an antigen-specif

180 oil phase can be used as a promising way of protecting highly unsaturated oils such as FO against ox

181 ession of IFN-stimulated genes (ISGs), which protect hosts from infection.

182 disease.IMPORTANCE We report that naturally protected HSV-1-seropositive asymptomatic individuals de

183 nezolid has immunomodulatory properties that protect human neutrophils from injury and provides insig

184 hibiting necroptosis or interferon signaling protects human organoids derived from individuals harbor

185 sing PhFCl/AgNO(3), a primary alcohol can be protected in good yield in the presence of a primary amm

186 These tubes are molded and protected in part by apical extracellular matrices (aECM

187 amten-bound myosin heads are not permanently protected in the SRX state but can be recruited into act

188 y for functional complementary mutations may protect individuals from FA.

189 Barrier systems also protect interior coastal communities from storm surges a

190 ct, we demonstrate a novel approach aimed at protecting islets before Tx in nonhuman primates (NHPs)

191 ng layer is softly deposited over the SAM to protect it during the deposition of the metal electrode

192 eldmannii, suggesting that this symbiont may protect itself and its host from damaging light radiatio

193 ty of S. aureus to secrete cytolytic toxins, protect itself from several aspects of the human innate

194 cating that these genes encode proteins that protect K. pneumoniae against neutrophil-related effecto

195 Protecting land to save biodiversity is a cornerstone of

196 sh water assessments may not be managing and protecting large volumes of deep fresh groundwater.

197 g plating, making it intrinsically unable to protect Li.

198 d during oxygen and amino acid depletion and protects LRS from degradation.

199 Its primary role is to protect lung tissue by inhibiting neutrophil elastase.

200 While efforts to restore and protect mangroves appear to be effective over decadal ti

201 upon DNA damage, whereas S429A substitution protects MDM2 from auto-degradation.

202 The ability of PolyRad to protect melatonin structure was also carried out using 0

203 Studies have suggested that estrogens may protect mice from AKI.

204 ion, also have anti-inflammatory properties, protect mice from sepsis, and prevent IL-1beta secretion

205 s (0.125 mg/kg and 0.25 mg/kg) significantly protected mice against CDI with 100% and 80% survival, r

206 P7C3-A20 also protected mice from BBB degradation after acute TBI.

207 g antibodies against TNF-alpha and IFN-gamma protected mice from mortality during SARS-CoV-2 infectio

208 nsitization, reduced total IgE serum levels, protected mice from passive and active IgE sensitization

209 Ucp1) expression in white adipose tissue and protects mice from developing obesity and insulin resist

210 teer in an RTS,S/AS01 clinical trial, and it protects mice from infection by malaria sporozoites.

211 r in myeloid cells using the Cre-loxP system protects mice from lethal sepsis (caecal ligation and pu

212 could cut biodiversity losses by two-thirds, protecting most endangered species while maintaining hig

213 ple myeloma cell survival and progression by protecting multiple myeloma cells from oxidative stress-

214 Since sestrin also protected muscles against aging-induced atrophy, our fin

215 t maternal immunization with DeltagD-2 would protect neonates.

216 is intact, only 9.7% of Earth's terrestrial protected network can be considered structurally connect

217 The lead agent protects neurons from death in vivo.

218 ly acquired maternal GBS-specific antibodies protect newborns from early-onset disease, yet their imp

219 a(21)Te(13), reveal the presence of symmetry-protected nodal crossings in the quasicrystalline and ap

220 rnal immunization with the trivalent vaccine protected offspring against nHSV-disseminated disease an

221 Significantly, this approach protected offspring from long-term behavioral morbidity.

222 nd memory, we tested a hypothesis that sleep protects old memories from being forgotten after new lea

223 at activation of pancreatic ER kinase (PERK) protects oligodendrocytes against inflammation in the ex

224 ndividual and community level to promote and protect oral health, as well as prevent and treat common

225 e proposed to act as molecular chaperones to protect other proteins from stress-induced damage.

226 cated laryngeal sensory motor reflex circuit protects our airways from aspirated foods or liquids.

227 the national response to COVID-19 can better protect Pardo and Black Brazilians, as well as the popul

228 regarding ERPOs are a potential tool to help protect patients or family members from harming themselv

229 osphate levels within the normal range, thus protecting patients with nephropathic cystinosis from el

230 the reductive deprotection of aryl sulfonyl-protected phenols.

231 n, and the sequestration of miR399 molecules protects PHO2 mRNA from complete degradation.

232 y cell walls provide a physical barrier that protects plants from pathogens, promotes tolerance to ab

233 tramannosyl-H-phosphonate provided the fully protected PLM anchor.

234 SERCA activation, presumably because 14-3-3 protected PLN pentamers from dephosphorylation.

235 nt A-tail from uridylation and decay thereby protecting pre-mRNA upon KPAF3 displacement by editing.

236 arly pregnancy are urgently needed to better protect pregnant women and their newborns.

237 Base treatment then affords a protected pseudodisaccharide, which functions as a glyco

238 ent is to assist other agencies charged with protecting public health, without minimizing the persona

239 practical way to encode and manipulate error-protected quantum information.

240 toxicity by SIR-based early CNI minimization protects renal function only short-term after LT in the

241 FAM111A, but not SPRTN, protects replication forks from stalling at poly(ADP-rib

242 flavonoids prior to light insult remarkably protected retina from deterioration and preserved its fu

243 We here show that cereal bran protects retinyl palmitate (RP) during simmering and sto

244 of Ser(3) may be an additional mechanism to protect RGS2 from FBXO44-mediated proteasomal degradatio

245 t tolerance to moderate high temperature and protected root meristematic cells from heat-induced cell

246 OAE, whose potency did not differ from SAE, protected ROS-exposed Caco2 cells against oxidative (78%

247 Heat-treated rice bran protected RP the best during forced storage, with a 35%

248 imilarly to P. aeruginosa, we show that heme protects S. aureus from CP-mediated inhibition of iron u

249 sumption of hard foods, such as mechanically-protected seeds, but dental microwear analyses are not.

250 We performed Protect-seq on the human colon cancer cell line HCT-116

251 indings suggest that the persistent cohesion protects short telomeres from inappropriate recombinatio

252 nd over 40% of the total area of terrestrial protected sites.

253 inimise accumulation of lipid metabolites to protect skeletal muscle insulin signalling following 7 d

254 TET2 knockdown in BRCA2-deficient cells protected stalled replication forks (RFs).

255 Autophagy can protect stressed cancer cell by degradation of damaged p

256 evolving telomere proteins bind, extend, and protect telomeric DNA, which itself evolves slowly in mo

257 the PPP5C-FKBP51 axis to inhibit I(SOC) and protect the endothelial barrier against calcium entry-in

258 shortening of telomeres, the structures that protect the ends of chromosomes, eventually triggering c

259 Suv39h2 in depositing sufficient H3K9me3 to protect the entire hematopoietic system from changes ass

260 otherapy that can prevent recrudescences and protect the future of ART-based combination therapies.

261 The additional three nucleotides may protect the inhibitor from excision by the viral 3'-5' e

262 A results in high-quality hybrid layers that protect the resin-dentin interface from harmful biologic

263 Inhibition of LncRNA MALAT1 has potential to protect the retina from oxidative damage and to prevent

264 bert 2006; Mandelbaum 2019) and functions to protect the self-concept against evidence of incompetenc

265 The irrational forms of attitude change that protect the self-concept in dissonance reduction are use

266 ids after 30 days-storage, respectively) and protected the oil against volatile compound formation (h

267 ows uptake of nutrients while simultaneously protecting the cell from harmful compounds.

268 liquid-air interface of the liquid droplet, protecting the cells inside the droplet from the bacteri

269 f mitochondrial respiration, thus ultimately protecting the fetus from the potentially dire consequen

270 o the innate immune system and contribute to protecting the host through killing of infected, foreign

271 ized epithelia, and plays a critical role in protecting the human body from infections.

272 hyperglycemic non-obese diabetic (NOD) mice, protecting the insulin-producing beta-cells from destruc

273 lated activities in international waters and protecting the marine environment from the harmful effec

274 ns to improve ohmic contact resistance while protecting the top surface of the diamond channel from d

275 Indeed, mecA protects the bacteria against increased cell-envelope pe

276 Our data suggest that BACS lung preservation protects the dual circulation inherent to the lungs, fac

277 s crucial for normal ER lipid metabolism and protects the ER from dysfunction.

278 n asymmetric intermediate, because Cas1-Cas2 protects the PAM sequence, which helps to define spacer

279 The digestive enzyme chymotrypsin protects the pancreas against pancreatitis by reducing h

280 is, a multilayered epithelium, surrounds and protects the vertebrate body.

281 Therefore, how organisms protect their future progeny from damage in a fluctuatin

282 difications as a counterdefense mechanism to protect their genomes against restriction.

283 es have evolved counterdefense mechanisms to protect their genomes from R-M cleavage by covalent modi

284 erse posttranslational defense mechanisms to protect their proteins, the main targets of HOCl, from H

285 for granting wider access to such data while protecting their owners.

286 ls to trigger immune evasion strategies that protect them against imminent immune attack.

287 xpression of antiviral effectors that safely protect them from various viruses.

288 that individuals in communities can enact to protect themselves and others: use of tissues to catch e

289 with maintained anti-ischemic efficacy while protecting these patients against the excess risk for bl

290 consider preventive treatment of malaria to protect this age group and advance the goal of malaria e

291 Overall, we show that protecting Tie2 shedding might offer a new therapeutic o

292 T complex is an intramembrane chaperone that protects TMDs during assembly to minimize misfolding of

293 Short-term fasting protects tumor-bearing mice against the toxic effects of

294 ed from probiotic Lactobacillus plantarum to protect tuna fish against spoilage and quality loss in t

295 n genome encodes an arsenal of proteins that protect us against deadly viruses.

296 unction in hypertension, but increased Sirt3 protects vascular function and decreases hypertension.

297 ntially recruited to the retinal vessels and protect vessels from diabetic damage.

298 Therefore, EBV BGLF2 might protect virus-infected cells from the type I interferon

299 tively package small RNAs (sRNA), which were protected within the vesicles against RNase treatment.

300 nsional topological phases and host symmetry protected zero-dimensional corner states.

301 The Zn(TFSI)(2) -TFEP@MOF electrolyte protected Zn anode enables a Zn||Ti cell to achieve a hi