ライフサイエンスコーパス: protect against

1 strains pediatric norovirus vaccines should protect against.

2 us, NFAT5 is activated by the stress that it protects against.

3 ssue-resident memory T cells, H5N1 (2:6) was protected against a heterologous challenge from H3N2 vir

4 ing non-human primates with PfGARP partially protects against a challenge with P. falciparum.

5 pineal gland hormone that has been shown to protect against Abeta toxicity in cellular and animal st

6 we demonstrated that tau suppression did not protect against Abeta-induced damage of long-term synapt

7 de some clues to understanding how melatonin protects against Abeta, and that choice of chain perdeut

8 at reduced PME-1 expression in these animals protects against Abeta-induced impairments without impac

9 ation with both vaccines prevented fever and protected against abortion.

10 Cells are protected against acetaldehyde-induced damage by DNA cro

11 tes beta cell growth and islet survival, and protects against activation of apoptosis and autophagy p

12 s to improve antitumor responses, even while protecting against active influenza virus lung infection

13 those with underlying chronic conditions, to protect against acute cardiovascular events associated w

14 ntial opposing effects; adenosine can either protect against acute lung injury via adenosine receptor

15 also tested whether TRV130 maintenance would protect against acute oxycodone-induced decreases in nuc

16 ur findings support a causal role for VGF in protecting against AD pathogenesis and progression.

17 we showed that loss of SIK1 kinase activity protected against adverse cardiac remodeling and heart f

18 d whether a MAIT cell priming strategy could protect against aerosol Mycobacterium tuberculosis infec

19 hat a prolonged infection with T. gondii may protect against age-associated decline in cognition.

20 gical-that have been found to slow aging and protect against age-related disease in various organisms

21 te into cells; disrupting their function can protect against age-related metabolic diseases and can e

22 ll heat shock proteins in adulthood, thereby protecting against age-related proteostasis collapse.

23 hibition of RAGE but not TLR4 signalling may protect against airway neutrophilia and AHR in COPD.

24 ptive treatment with colchicine or metformin protected against AKI, with lower serum creatinine, impr

25 genetically deficient in cGAS and IRF3 were protected against ALD.

26 Extracellular purines, adenosine and ATP, protected against ALI induced by purified LPS.

27 nsal bacterial content in drinking water may protect against allergic diseases.

28 nor refute the hypothesis that rosuvastatin protects against aminoglycoside nephrotoxicity.

29 st that AeAmt1 function in spermatozoa is to protect against ammonia toxicity based on our observatio

30 itable symbiont, Hamiltonella defensa, which protects against an important natural enemy, the parasit

31 umans and mice, whereas PGE(2) stabilization protects against anaphylactic reactions.

32 E(2) attenuate MC activation via EP2/EP4 and protect against anaphylaxis.

33 response beyond antibody treatment and fully protected against anaphylaxis.

34 Of 16 weeks of EPIT significantly protects against anaphylaxis by promoting a faster recov

35 l inhibition of the MNK-eIF4E signaling axis protected against and reversed spontaneous pain and PNI-

36 lso found that neither PDYN nor KOR knockout protected against anxiety caused by alcohol drinking.

37 roteins, including HMGI-C, which is known to protect against apoptosis.

38 d to human disease, but it has been shown to protect against Argentine hemorrhagic fever-like disease

39 the fly's auditory neurons accelerated - or protected against - ARHL.

40 Greenspace exposure may protect against arterial stiffness by promoting physical

41 esis of glutathione, an antioxidant that may protect against As-induced oxidative stress.

42 CR and Cyquant assay, we showed that miR-124 protects against As-induced cytotoxicity in neural cells

43 ent in preimmunized mice, although they were protected against associated disease.

44 hildren breastfed for at least 3 months seem protected against asthma at 8 years old.

45 non-B6-derived region of chromosome 11 that protected against B6.Y (POS) sex reversal.

46 This region, which we call Mod13, protects against B6.Y (POS) sex reversal in a proportion

47 bulin isotype, has the longest half-life and protects against bacterial and viral infections.

48 Estrogens protect against bone loss by decreasing osteoclast numbe

49 phosphorylation, attenuates cerebral edema, protects against brain damage, and improves outcomes in

50 esolving chronic intestinal inflammation and protecting against CAC in response to the commensal flor

51 ed daily by most individuals, are thought to protect against cancer and other diseases(1); however, t

52 e identification of chromosome 21 genes that protect against cancer when overexpressed.

53 Acute senescence induction protects against cancer and limits fibrosis, but lingeri

54 stability, suppress replication stress, and protect against carcinogenesis.

55 Helminths may protect against cardiometabolic risk through effects on

56 lone does not cause cardiac dysfunction, but protects against cardiomyopathy in chronically obese mic

57 ays enhanced longevity/exercise capacity and protects against cardiovascular/metabolic disease.

58 sion, this is evidence of a vaccine that can protect against CCHFV-induced disease in a non-human pri

59 the BA-binding resin sevelamer hydrochloride protected against CDCA-induced loss of barrier function.

60 erate reactive oxygen species (ROS) and thus protect against cellular damage.

61 ion, suggesting that S-OPA1, and not L-OPA1, protects against cellular stress.

62 s suggest that light ethanol consumption may protect against cerebral I/R injury by suppressing post-

63 ockade of IL-18 receptor in the brain helped protect against cerebrovascular dysfunction despite prol

64 ate or BeninDeltaMGF virus, animals were not protected against challenge with the virulent Benin 97/1

65 hydrosalpinx formation, vaccinated mice were protected against challenges with serovars D (UW-3/Cx),

66 the most favorable genetic background may be protected against CKD.

67 ted viral replication in the lungs, but both protected against clinical disease.

68 dence also suggests that flavanol-rich diets protect against cognitive aging, but mechanisms remain e

69 IBD whereas immunosuppressive M2 macrophages protect against colitis.

70 heir candidate vaccines to immunize women to protect against congenital CMV disease and to prevent th

71 vaccine suggest that it has the potential to protect against COVID-19 through multiple beneficial mec

72 es are now being tested for their ability to protect against COVID-19, the authors also comment on th

73 sposable nonmedical face mask widely used to protect against COVID-19.

74 t CS-induced neutrophilia but were partially protected against CS-induced mediator release and AHR.

75 In contrast, TLR4(-/-) mice were not protected against CS-induced neutrophilia and had more s

76 TLR4(-/-) RAGE(-/-) mice were not protected against CS-induced neutrophilia but were parti

77 hylaxis in these mice and also significantly protected against death during severe anaphylaxis.

78 -based cuticle on aerial plant surfaces that protects against dehydration is considered a fundamental

79 cavenging of mitochondrial H(2)O(2) does not protect against denervation atrophy, suggesting ETC gene

80 h high preexisting anti-DENV antibody titers protected against DENV1, DENV3, and ZIKV disease, interm

81 attenuated CORT-mediated weight changes and protected against depressive- and anxiety-like behavior.

82 This overhang must be protected against detrimental activities of nucleases an

83 This genetic activation of CD11b also protected against development of atherosclerosis in the

84 inflammation, improve vascular function, and protect against diabetes-associated atherosclerosis in t

85 ve beta-cell mass and beta-cell function and protect against diabetes.

86 Dietary fiber protects against diabetic nephropathy through modulation

87 lerance and increases energy expenditure and protects against diet-induced obesity and insulin resist

88 EEEV-33 and EEEV-143 protect against disease following stringent lethal aeros

89 ors to strengthen the mucus barrier and thus protect against disease.

90 lenge, whereas the reversed infection scheme protected against disease in response to a secondary vir

91 s based on bioactive ingredients in order to protect against diseases and to develop healthy diets.

92 (2S,6S)-HNK and (2R,6R)-HNK protected against distinct stress-induced behaviors in b

93 rized information in working-memory could be protected against distracting influences by processes of

94 d cardiac superoxide levels and that MTP-131 protects against DKD and preserves physiological superox

95 e in the adult fly brain and that polyploidy protects against DNA damage-induced cell death.

96 BRCA2 function at an ICL protects against DNA2-WRN nuclease-helicase complex and

97 In conclusion, TTP protects against dopaminergic oxidative injury by promot

98 6 or transfection with FOXO1-specific siRNAs protected against DOX-induced apoptosis and mitochondria

99 , where diversifying an investment portfolio protects against economic uncertainty.

100 This work identifies a novel role for FSTL-1 protecting against emphysema development independent of

101 Our results suggest that m(6)A modification protects against endogenous dsRNA formation and a delete

102 studies revealed that miR-214(-/-) mice were protected against endothelial dysfunction, oxidative str

103 ays a dual regulatory role in macrophages by protecting against ER stress and promoting anti-inflamma

104 tide combinations, peptide binding onto MHCI protected against ERAP1-mediated trimming.

105 Similarly, tau suppression did not protect against exogenous oligomeric tau-induced impairm

106 of butyrate as a pivotal HM compound able to protect against FA.

107 rehensive Fatigue Risk Management Systems to protect against fatigue in nurses, midwives, and other s

108 disruption of specific small nucleolar RNAs protects against fatty acid-induced cell death and remod

109 nd human cancer cells, ether-lipid synthesis protects against ferroptosis.

110 We propose that DDX11 is a DNA helicase protecting against G4 induced double-stranded breaks and

111 th provide effective humoral immunity and to protect against genomic instability and neoplastic trans

112 Short term IL-22 production protects against genotoxic stress, whereas uncontrolled

113 fore, we hypothesized that TREK-1 activation protects against HALI.

114 OVP appears to protect against HCFO-CDI during in-patient stay in targe

115 ion of heat-shock-induced gene expression to protect against heat stress.

116 rt-chain fatty acids butyrate and propionate protect against hepatic IR injury and intestinal apoptos

117 ous administration of butyrate or propionate protected against hepatic IR injury in intestinal TLR9 d

118 vaccine that would be safe, and effectively protect against heterologous infection.

119 8, bound GP38 with subnanomolar affinity and protected against heterologous CCHFV challenge in a STAT

120 n could promote brown/beige adipogenesis and protect against HFD-induced adiposity in offspring.

121 /J mouse model showed that the human vaccine protected against high-dose challenges of the nonencapsu

122 ntrast, hypothalamic overexpression of SH2B1 protects against high fat diet-induced obesity and metab

123 roadly neutralizing antibodies (bnAbs)-could protect against highly mutable pathogens.

124 oadly neutralizing antibody (bNAb) VRC01 can protect against HIV acquisition.

125 antibodies (bnAbs) can suppress viremia and protect against HIV infection.

126 Lactobacillus species may protect against HIV partly by reducing FGT inflammation.

127 Consequently, TEC-derived LXRalphabeta protects against homeostatic premature involution and or

128 Species protecting against hospital-related C. difficile acquisi

129 Sting(S365A/S365A) mice protect against HSV-1 infection, despite lacking the STI

130 Additionally, PG protected against HSV-1 infection and disease progressio

131 y in the face of cellular stress is vital to protect against human diseases such as cancer.

132 Circulating APOL1 lyses trypanosomes, protecting against human sleeping sickness.

133 vy chain) promoter (alpha MHC JunD(tg)) were protected against hyperglycemia-induced cardiac dysfunct

134 new insight into the mechanisms involved in protecting against hypertensive heart failure.

135 acologic activation of the PPARgamma pathway protects against hypoxia-associated IUGR, we used an exp

136 me extracellular superoxide dismutase (SOD3) protects against hypoxia-induced PH.

137 Additionally, the mechanisms by which EVs protect against I-R injury are discussed.

138 and recruitment of BM sprocs, which markedly protects against I/R injury, even in severely steatotic

139 reduction of Notch3 in Col4a1(+/G498V) mice protected against ICH.

140 us, the glycan cap of GP1 may allosterically protect against inactivation of EBOV by premature trigge

141 We determined that these metabolites protect against increased gut permeability associated wi

142 ddition, non-CKD AhR(-/-) knockout mice were protected against indoxyl sulfate-induced blood-brain ba

143 Furthermore, mdxS3E mice were protected against inducible arrhythmias, related lethali

144 tegy for durable elicitation of HIV bnAbs to protect against infection and as a contributor to a func

145 n African gene variants of APOL1, G1 and G2, protect against infection by species of trypanosomes tha

146 ty of specific commensal microorganisms that protect against infection is unclear.

147 Nanotube transfer of GNLY allows dNK to protect against infection while leaving the maternal-fet

148 nce broadly reactive HA stalk antibodies can protect against infection, and universal vaccine platfor

149 : how host-microbiota metabolic partnerships protect against infection; competition for glucose betwe

150 umsporozoite antibody titers in participants protected against infection.

151 n OmpD from Salmonella Typhimurium (STmOmpD) protects against infection.

152 ate, whereas the antioxidant glutathione may protect against inflammation-induced oxidative stress.

153 mAb to G-CSFR would reduce inflammation and protect against injury in a mouse model of warm renal IR

154 study, we investigated whether dietary MCFAs protect against insulin resistance induced by a hypercal

155 significantly ameliorates glucose tolerance, protects against insulin-resistance onset and remarkably

156 his discovery, we evaluated whether they can protect against invading dsDNA in Escherichia coli and f

157 ngs show that miniature Cas12f nucleases can protect against invading dsDNA like much larger class 2

158 nt protein-based vaccine that is licensed to protect against invasive group B meningococcal disease.

159 ive stress, hearts from Alkbh7(-/-) mice are protected against IR injury, in a manner blocked by GLO-

160 s study was performed to investigate if UDCA protects against ischaemia-induced and reperfusion-induc

161 pporting this, P2X4-deficient (KO) mice were protected against ischemic AKI with significantly attenu

162 th a selective P2X4 antagonist (5-BDBD) were protected against ischemic AKI.

163 966 alleviated the inflammatory response and protected against ischemic stroke by regulating the AIM2

164 Microglia-selective deletion of Tak1 also protects against ischemic stroke in prolonged obesity.

165 nd examine factors that may contribute to or protect against its development.

166 when, where and how commensal Bacteroidetes protect against K. pneumoniae colonization and contagion

167 he presence of more distinct representations protected against later false memory.

168 However, vaccination with CspZ does not protect against LD infection.

169 nity to saliva or distinct salivary proteins protects against leishmaniasis in various animal models.

170 opes induce EBOV-neutralizing antibodies and protect against lethal EBOV challenge.

171 activity, neutralize the virus in vitro, and protect against lethal IBV infection in mice in prophyla

172 cacy of the multivalent vaccine candidate to protect against lethal virus challenge.

173 lasma from a recovered patient with COVID-19 protected against lethal disease.

174 or PVL components alone were only partially protected against lethal pneumonia, whereas those vaccin

175 at the presence of the indigenous microbiota protects against LIP-induced osteonecrosis.

176 Glutathione peroxidase 4 (GPX4) protects against lipid peroxidation (LPO) and cell death

177 In mice, the administration of DMF protects against lipopolysaccharide shock and alleviates

178 ng and memory center in the Drosophila brain protects against locomotion and short-term memory functi

179 moral and cell-mediated immune responses and protects against lung infection, inflammation, and patho

180 te to growing evidence that suggests BCG may protect against M. tuberculosis infection as well as dis

181 , it is unknown if innate immune memory also protects against M. tuberculosis In this study, by using

182 We tested the hypotheses that NBResilience protects against MACE, and that it does so through decre

183 and none of those randomized to placebo were protected against malaria infection.

184 c insight into how they extend healthspan or protect against MARDs.

185 or the development of potential therapies to protect against Marek's disease while also providing a r

186 nuclei, and chromatin, but how the genome is protected against mechanical stress is unclear.

187 thionine restriction, a dietary regimen that protects against metabolic diseases and aging, represses

188 pansions is unclear given its normal role in protecting against microsatellite instability and while

189 a key repressor of protein translation, can protect against misfolded protein stress and toxicities

190 position 147 residue were more effective at protecting against morbidity and mortality following inf

191 Highly expressed KIR3DL1 variants protect against more debilitating symptoms of PD, strong

192 Indeed, pharmacological inhibition of HDAC6 protects against MT disorganization and reduces the size

193 may elicit a narrow immune response and not protect against multiple H2 influenza viruses.

194 y of current live vector-based approaches to protect against multiple pathogenic species of Ebola is

195 and as recombinant vaccine viral vectors for protecting against multiple avian diseases.

196 3 receipt increased antibody levels that may protect against mumps virus infection for longer than pr

197 cutoff, significantly more participants were protected against mumps virus infection up to 1 year aft

198 tanding of all immune components involved in protecting against Mycobacterium tuberculosis infection

199 signaling in myeloid cells was sufficient to protect against nephritis.

200 neurons enhances survival under hypoxia and protects against neurodegeneration in a tauopathy model.

201 that modulates actin dynamics and branching, protects against neuroinflammation in experimental autoi

202 , our results support a model by which Tip60 protects against neurological impairments in different N

203 Mice deficient in PI16 are protected against neuropathic pain.

204 he protein's cis interaction, which helps to protect against neurotoxicity carried out by its N termi

205 alent (gC2, gD2, and gE2) subunit vaccine to protect against nHSV.

206 antibodies into the neonatal circulation and protects against nHSV neurological sequela and mortality

207 ated with ISRIB prior to noise-exposure were protected against noise-induced synapse loss.

208 maintaining normal hearing thresholds while protecting against noise-induced synaptopathy, via selec

209 lin-induced hepatic cyclin D1 expression and protected against obese/diabetic hepatocarcinogenesis.

210 s via activating non-canonical thermogenesis protect against obesity.

211 n linked with weight gain, whereas fiber may protect against obesity.

212 or Lsd1 inhibition, reduced lipogenesis and protected against obesity-associated NAFLD and insulin r

213 augmented in vivo and in vitro GSIS and are protected against obesity-induced glucose intolerance.

214 ture through thermogenic adipose tissue, and protected against obesity.

215 y (CFA/I) fimbria, is highly immunogenic and protects against oral challenge with CFA/I-positive (CFA

216 hese data suggest that the lees' capacity to protect against oxidation decreases over time, which cou

217 -3 PUFAs concentrates entrapped in SDNLs was protected against oxidation in comparison to the free om

218 n endogenous neuroestrogen that can strongly protect against oxidative neuronal damage.

219 tion of mitochondrial oxidative capacity may protect against oxidative stress associated with birth w

220 ld increase adenosine receptor signaling and protect against P. aeruginosa-induced acute lung injury.

221 sing safe adjuvant platform that can help to protect against pandemics and future infectious threats.

222 iotas contain beneficial microorganisms that protect against pathogen colonization; treatment with an

223 fusion, pave the way for immunogen design to protect against pathogenic hantaviruses.

224 are vital for adaptive immune responses that protect against pathogens and cancers.

225 at prime myeloid cells, such as macrophages, protect against pathogens(1,2).

226 s up-regulated in response to cell stress to protect against pathological cell death in multiple dise

227 ips the epiglottis over the laryngeal inlet, protecting against penetration and aspiration of food in

228 ound state of a fermionic condensate is well protected against perturbations in the presence of an is

229 Thus, cellular plasticity in seeds protects against perturbations to its storage capabiliti

230 erent states in an oscillator encode a qubit protected against phase-flip errors(1,2).

231 NK) cells promote placentation, but how they protect against placental infection while maintaining fe

232 ical role of Arg1 in microglia activation to protect against poly (I:C) imparted neuropathology and a

233 ization induces immune memory responses that protect against primary VZV infection, chicken pox.

234 and we would hypothesize that it may act to protect against prolonged placental hypoxia seen in pree

235 Likewise, Keap1(f/f) pups were protected against prolonged (96 h) hyperoxia-induced hyp

236 oteostasis may hold therapeutic potential to protect against protein aggregation-associated cellular

237 Liver-selective MMP-9 inhibition to protect against proteolytic cleavage of hepatic VEGF usi

238 Inhibition of USP7 protected against proteotoxicity in mammalian neurons, a

239 so activates matrix Gla protein (MGP), which protects against pulmonary and vascular elastic fiber da

240 icrobiota that developed after radiation and protected against radiation-induced damage and death in

241 c sequencing could document whether vaccines protect against reactivation or reinfection of CMV or bo

242 ridioides (Clostridium) difficile toxins may protect against recurrence of C. difficile infection (rC

243 nfection induced antigen-specific memory and protected against reinfection.

244 s bacterial infection, promotes healing, and protects against reinfection.

245 CD8(+) T cells (T(RM) cells) are crucial in protecting against reinvading pathogens, but the impact

246 Treatment with anti-G-CSFR protected against renal IRI in a dose-dependent manner,

247 lly, we found that endothelial Phd2 ablation protected against renal ischemia-reperfusion injury by s

248 ts their de-differentiation in the adult and protects against renal fibrosis.

249 proteome maintenance machinery, and proteins protecting against ROS are more resistant in D. radiodur

250 elicited alpha-hemolysin-specific antibodies protect against S. aureus-induced dermonecrosis, a key f

251 Whereas the host response to AA protected against S. pneumoniae lung disease, the IL-6 d

252 ide that modulates M cells and SFB levels to protect against Salmonella infection.

253 ding and neutralizing antibody responses and protected against SARS-CoV-2-induced weight loss, pneumo

254 oV-2 as well as CD8(+) T cell responses, and protects against SARS-CoV-2 infection in the lungs and n

255 deficits, revert autistic-like behaviors and protect against seizures.

256 he synovial fluids of arthritis patients and protect against sepsis.

257 ells, as well as a compensatory mechanism to protect against several pro-death stimuli in fibroblasts

258 racing to develop and test novel vaccines to protect against severe acute respiratory syndrome corona

259 at RhCMV-vectored SIV vaccines significantly protect against SIV pathogenesis.

260 activity of neuronal and lymphoid CB(2)that protects against spontaneous and evoked neuropathic pain

261 Dorsal root ganglia nociceptors protect against STm colonization, invasion, and dissemin

262 c mice overexpressing VDR in beta-cells were protected against streptozotocin-induced diabetes and pr

263 Enhancing stress resilience could protect against stress-induced psychiatric disorders in

264 Moreover, the A-allele homozygotes were protected against stress-induced decreases in AEA and ne

265 use model, AA homozygous mice were similarly protected against stress-induced decreases in AEA, both

266 ty, assessed via electrodermal activity, and protected against stress-induced negative affect, measur

267 acid (AsA), is the most abundant antioxidant protecting against stress damage in plants.

268 IFN-beta pretreatment was more effective in protecting against subsequent WNV infection in wt cells

269 create a screening layer around NO sensors, protecting against such chemical interference in vitro.

270 ore efficient than a uniform distribution in protecting against systemic bacterial dissemination.

271 d to restrict Th1 cell-mediated immunity and protect against T1D.

272 tenofovir treatment, indicating that PrimPol protects against tenofovir-induced mitochondrial toxicit

273 Cells possess multiple mechanisms that protect against the accumulation of toxic aggregation-pr

274 y genetically engineered pathogens, and thus protect against the potential misuse of synthetic biolog

275 suppresses toxic tau accumulation, which may protect against the progression of AD and related tauopa

276 will reduce inflammatory cell activation and protect against the progression of atherosclerosis.

277 s that allergic immune reactions can help to protect against the toxicity of venoms.

278 products stored in room temperature must be protected against the influence of humidity.

279 le rats suggest that female rats are perhaps protected against the more pronounced changes in CSF and

280 viable therapeutic approach for selectively protecting against the pathologic actions of Abeta in AD

281 llone augments the mitochondrial network and protects against the complex I inhibitor MPP+.

282 Breastfeeding modulates infant growth and protects against the development of obesity.

283 Indeed, JNK1/2 deficiency in hepatocytes protects against the development of steatosis, suggestin

284 g early infancy, the nonfood environment may protect against this drive and prevent obesity developme

285 how that a major cellular role of PrimPol is protecting against toxicity caused by ART and individual

286 APOL1 protects against trypanosome infections by forming ion c

287 d preventive therapy (IPT) is widely used to protect against tuberculosis (TB) in people living with

288 together, our results indicate that Cyp2c44 protects against tumor growth and metastasis by preventi

289 ion that led to spontaneous autoimmunity but protected against tumour growth in multiple cancer model

290 also maintains the 11-cis configuration and protects against unwanted retinaldehyde activity.

291 f aspirin (acetylsalicylic acid [ASA]) could protect against UVB-induced DNA damage and skin carcinog

292 These results indicate that ASA can protect against UVB-induced inflammation in skin and red

293 ation-induced heterotypic immunity which can protect against Variola and Monkeypox disease.

294 le in maintaining intestinal homeostasis and protecting against various intestinal diseases such as c

295 Avirulent 5ASKH-primed BALB/c mice were protected against virulent L. major challenge infection.

296 gion, our data demonstrate that SP-D may not protect against virus containing these HA subtypes.

297 ally found in trials of vaccines designed to protect against viruses that cause only acute infections

298 Our study demonstrated that TFEB protects against VSMC apoptosis and AAA.

299 nd human anti-NS1 monoclonal antibodies that protect against ZIKV in both non-pregnant and pregnant m

300 uggest that APP is a restriction factor that protects against ZIKV by serving as a decoy receptor, an