ライフサイエンスコーパス: protection from

1 hanism involving PTH and FGF23 together with protection from 1,25(OH)(2)D(3) toxicity that is respons

2 more, sinapine provided plasmid DNA (pBR322) protection, from 2,2'-azobis(2-amidinopropane) dihydroch

3 m 5' exonuclease and the (S) isomer provided protection from 3' exonuclease in the context of a termi

4 For example, protection from 5' decapping promotes accumulation of mR

5 The (R) isomer provided protection from 5' exonuclease and the (S) isomer provid

6 l response in immunized mice does not impair protection from a homologous challenge; however, it does

7 rio bacteriovorus HD100 provided significant protection from a lethal challenge of Yersinia pestis CO

8 m, it remains unclear how the germline gains protection from a new transposon invasion.

9 mB SCV failed to elicit trained immunity and protection from a secondary infectious challenge in the

10 Subsequent infants obtained limited protection from a single antenatal dose, but revaccinati

11 style, and confer both susceptibility to and protection from a variety of human diseases.

12 These polymers afford the producing bacteria protection from a wide range of physical, chemical, and

13 us is a key parameter of protection and that protection from acquisition by a single bNAb might requi

14 of SARS-CoV-2 but also play an early role in protection from acute disease.IMPORTANCE Syrian hamsters

15 critical role of barrier epithelial cells in protection from acute illness and chronic disease after

16 n SIRP-alpha cytoplasmic recruitment confers protection from acute kidney injury.

17 is a transcription factor (TF) that mediates protection from adverse effects of hypertonicity by incr

18 given within hours post MI, induces lasting protection from adverse remodeling concomitant with: 1)

19 and IL-33 to enhance Treg- and ILC2-mediated protection from AKI, bears strong therapeutic potential.

20 By contrast, we observe protection from all symptomatic dengue disease at high a

21 ock type 2 inflammation, which translates to protection from allergen-induced lung function impairmen

22 stimulation, and host genetics in conferring protection from amebiasis.

23 Patient-based protection from anaphylaxis was 76% (4/17) in cMCD vs. 1

24 e findings have implications for Ab-mediated protection from and control of HIV-1 infection.

25 cellular cytotoxicity (ADCC) responses with protection from and delayed progression of HIV-1 infecti

26 ts on APP beta/alpha-processing suggest that protection from and pathogenesis of dementia depend upon

27 been shown to play an integral role in both protection from and susceptibility to infections.

28 ion in endothelial cells, and contributes to protection from angiotensin II-induced hypertension.

29 fying new habitats that will require further protection from anthropogenic threats like fixed fishing

30 fectivity, decrease of cell reinfection, and protection from antibody-dependent cellular cytotoxicity

31 D88 signaling is required for proliferation, protection from apoptosis and expression of activation/m

32 cluding cell proliferation, gene expression, protection from apoptosis, and immune regulation.

33 on (HR, 0.57; P <= 0.01) was associated with protection from AR.

34 an array of responses that provide them with protection from attack by microorganisms and other preda

35 The persistent protection from autoimmune destruction was paralleled by

36 y help to develop therapeutic strategies for protection from autoimmune neuroinflammation.

37 entanoate-induced regulatory B cells mediate protection from autoimmune pathology.

38 Thus, protection from autoimmunity afforded by particular MHC/

39 This newly defined mechanism confers protection from autoimmunity during pregnancy and repres

40 r sodium activates Th17 cells, which provide protection from bacterial and fungal infections.

41 ions, and have been shown to be essential in protection from bacterial sepsis.

42 Lower protection from BCG with increasing M. tuberculosis expo

43 trate that protected areas provide important protection from biological invasions, but invasions may

44 the mucosal BRSV-NP vaccine, are afforded no protection from BRSV challenge and have significant abno

45 al that SLC7A2 has a significant role in the protection from CAC in the setting of chronic colitis, a

46 e oxalate, and its potential contribution to protection from calcium oxalate kidney stones.

47 Furthermore, we show that protection from cardiovascular disease in the absence of

48 tin (Acrp30) is an adipokine associated with protection from cardiovascular disease, insulin resistan

49 lso unexpectedly associated with an apparent protection from cardiovascular disease.

50 ulant activity in mice with a dose-dependent protection from carotid occlusion in a ferric chloride-i

51 Protection from casein challenge was assessed at 4 and 1

52 res ensure chromosome length homeostasis and protection from catastrophic end-to-end chromosome fusio

53 re T-cell activation and differentiation and protection from cell death.

54 howing that the control of LASIV viremia and protection from challenge can occur even after CD8beta25

55 In conclusion, improved protection from challenge infection emphasizes further e

56 The protection from challenge was associated with the suppre

57 Biofilms confer many advantages, including protection from chemicals (including antibiotics), entra

58 gainst excessive reactive oxygen species and protection from chemotherapy.

59 d moderately but significantly reduced cross-protection from CHIKV-vaccinated animals.

60 Concomitant with protection from chronic inflammation, H. pylori-infected

61 ylate (PEGDMA) hydrogel; this design ensures protection from circulating proteases and the foreign bo

62 phorylated, constitutively active) conferred protection from cisplatin that was similar to wildtype G

63 hese medulloblastoma cell lines and to their protection from cisplatin- and etoposide-induced apoptos

64 ing a novel ELISPOT assay is able to predict protection from CMV infection.

65 neutralization of IL-22 did not abolish the protection from colitis in Nkx2.3-deficient mice.

66 es, such as Arg2 or Nos2, demonstrating that protection from colitis requires l-arginine.

67 orrelated with a reduction in Th17 cells and protection from colitis.

68 articular stress, lettuce CBFs provide wider protection from combinations of abiotic stresses.

69 ces and hijack their regulatory function for protection from complement activation.

70 growth advantage in the IAV-infected LRT and protection from complement-mediated opsonophagocytosis d

71 to, although more modest than, the degree of protection from coronary artery disease predicted by the

72 can be scaled to screen people for antibody protection from COVID-19, a key parameter necessary to s

73 bilization of individual mRNAs presumably by protection from deadenylation (Mattijssen et al., 2017).

74 However, neutrophil depletion abrogated protection from death in Nlrp3(-/-) mice in response to

75 Our results showed protection from death in NLRP3-deficient (Nlrp3(-/-)) an

76 after-hyperpolarizations, and afforded full protection from degeneration in vivo in a neurotoxin Par

77 proteasome, it surprisingly conferred strong protection from degradation on the Gag-like protein CXX1

78 l DNA are associated with development of and protection from delirium in Caucasians and African Ameri

79 one to delirium should validate their use in protection from delirium.

80 ferred significant homotypic and heterotypic protection from DENV2-induced morbidity and mortality.

81 ivation of AMPK by allosteric mechanisms and protection from dephosphorylation, attributed here to sp

82 INTERPRETATION: Economic opportunities and protection from deportation for undocumented immigrants,

83 mber of admitted refugees, and rescission of protections from deportation.

84 ens with a defined niche for replication and protection from detection by host cytosolic pattern reco

85 1.07-2.13], respectively), and MICB*002 with protection from DHF in secondary DENV infections (OR, 0.

86 , although growth was slightly inhibited and protection from diet-induced obesity was less complete.

87 that this results in reduced weight gain and protection from diet-induced obesity.

88 betes (T1D) development while others provide protection from disease development.

89 -attenuated MAYV vaccine candidate in host's protection from disease induced by a virulent MAYV strai

90 terferon receptor-defective mice resulted in protection from disease induced by the virulent wt MAYV

91 nctional evidence of a mechanism of dominant protection from disease, in which HLA molecules associat

92 ic CD8+ T cells in the brain correlated with protection from disease.

93 al family Lachnospiraceae as a correlate for protection from disease.

94 ion loop plays a part in DNA replication and protection from DNA replication stress.

95 GluN2A-specific antagonists provide greater protection from DNRAb-mediated neuronal cell death than

96 Here, we report successful protection from DOX in two independent hPSC-CM lines, us

97 essing MYC-mediated apoptosis priming and in protection from drug-induced apoptosis.

98 de antibiotic-sensitive neighbors with leaky protection from drugs, as shown both in vitro and in viv

99 nd essential turmeric oils provides superior protection from DSS-induced colitis than curcumin alone,

100 This complexity of antibody-mediated protection from EBOV disease highlights the structural c

101 a strong dipolar coupling, and leading-order protection from electrical fluctuations.

102 ges with unique serine patterns that provide protection from endogenous murein hydrolases governing c

103 es likely due to opposite chirality and thus protection from endogenous proteins including proteases.

104 these insects with unique, enhanced food and protection from enemies and the elements.

105 Protection from enterotoxemic death correlated with the

106 nical settings where wounds urgently require protection from environmental and bacterial contaminatio

107 of their progeny lineages can offer broader protection from evolving pathogens than can a single, li

108 nowledge on the development of correlates of protection from existing vaccines could be harnessed to

109 and led to an almost complete Treg-dependent protection from experimental autoimmune encephalomyeliti

110 Protection from exposure to E-101 solution reactive oxyg

111 t, this regulatory mechanism is critical for protection from extensive injury and offers a novel targ

112 They provide protection from external piercing attacks and control ov

113 easing GVHD through two opposing mechanisms: protection from fatal immunity by amphiregulin expressio

114 liferation and the lipid peroxidase GPX4 for protection from ferroptosis of inner, matrix-deprived ce

115 lasmodium-induced inflammation and predicted protection from fever.

116 e amphiregulin injection sufficed to reverse protection from fibrosis after ischemia-reperfusion inju

117 sults revealed that Ne-TML exhibited maximum protection from fungal (75.40%) and aflatoxin B(1) conta

118 IL-17 mediates immune protection from fungi and bacteria, as well as it promot

119 y following infection result in differential protection from future infection.

120 bodies can provide lifelong surveillance and protection from future insults.

121 cted into the Cox model offering significant protection from GVHD development (listed in order of sel

122 hypovolemic shock, which was associated with protection from histamine-induced barrier dysfunction in

123 ulin-like receptor (KIR)-HLA combinations in protection from HIV infection and slower progression to

124 -HIV-1 co-receptor, coupled with findings of protection from HIV infection in individuals lacking CCR

125 FTC NPs resulted in significant (p = .0002) protection from HIV-1 (day 4: 80%, day 7 and 14: 60%, re

126 threshold that has been associated with high protection from HIV.

127 us suppressive immune responses in affording protection from HIV.IMPORTANCE CD40-CD40 ligand (CD40L)

128 selective stabilization of host proteins and protection from host defense.

129 ricoital use of tenofovir (TFV) gel provided protection from HSV-2 acquisition in the CAPRISA 004 stu

130 shed further light on the roles of VdCmr1 in protection from HT or UV irradiation, and the additional

131 ant ALVAC/gp120 alum vaccine provided modest protection from human immunodeficiency virus type 1 (HIV

132 mechanism by which BSJYD provides myocardial protection from hypertension.

133 ved in evasion of antitumor immune response, protection from hypoxia, angiogenesis, DNA repair, cell

134 and anti-inflammatory functions resulting in protection from IBD in mouse models.

135 Our results show that genes involved in protection from ice damage, including genes encoding ant

136 -induced immunity, or using extrapolation of protection from in-vitro immunoassay results.

137 eostasis throughout the body, participate in protection from infection and cancer, and likely promote

138 study to identify alternative correlates of protection from infection and disease in naturally expos

139 diverse antibodies, which may provide broad protection from infection and disease.

140 e followed by an rAd boost exhibit increased protection from infection by repeated intrarectal challe

141 bodies, additional serological correlates of protection from infection could aid the development of b

142 aps remain regarding serologic correlates of protection from infection or disease, and the degree to

143 B-1a cells provide immediate and essential protection from infection through production of natural

144 Plasma cells (PCs) are essential for protection from infection, and at the origin of incurabl

145 ens, neuron-immune interactions enhance host protection from infection, but for other pathogens, neur

146 idence that maternal antibodies provide some protection from infection, but gestational maternal anti

147 To provide improved protection from infection, novel influenza virus vaccine

148 inhibitors, decreased spreading and provided protection from infection.

149 ding and neutralization, resulting in better protection from infection.

150 aling, expanded VAT-Treg cells, resulting in protection from inflammation and improved metabolic indi

151 Protection from influenza virus infection is canonically

152 alk antibodies independently correlated with protection from influenza virus infection.

153 influenza viruses are often associated with protection from influenza virus infections.

154 For protection from inhaled pathogens many strategies have e

155 Further, protection from injury is achieved by pharmacologic bloc

156 pleted C57BL/6 mice demonstrated significant protection from injury, which was not seen in CD4(-/-) m

157 ignalling in intestinal epithelial cells and protection from intestinal injury.

158 ed CD8 T cells may play an important role in protection from intracellular pathogens that limit class

159 lating memory cells in the blood, and showed protection from intradermal challenge with melanoma cell

160 th cellular and humoral factors that provide protection from invading pathogens.

161 by cells at the injury site is critical for protection from IRI through bone marrow-derived adenosin

162 rp3 suppression is required for aPC-mediated protection from IRI.

163 tion, phosphorylation of Akt substrates, and protection from ischemia-induced injury.

164 ow that preoperative LPSx4 provides complete protection from ischemia-induced neuron loss and hindlim

165 Ca(2+) uptake in cardiomyocytes and partial protection from ischemia-reperfusion injury by reducing

166 rophil depletion in wild-type mice conferred protection from ischemic stroke to a similar degree as o

167 filtrates and urine albumin, consistent with protection from kidney damage.

168 CL-11(-/-) mice gained no additional protection from l-fucose administration, indicating that

169 report the first active vaccine that offers protection from lethal (+)-METH challenge in male Swiss

170 how that postexposure vaccination can confer protection from lethal outcome.

171 tenuated ZIKV strain resulted in significant protection from lethal subcutaneous ZIKV challenge, furt

172 tivity to light, and measured what degree of protection from light-induced damage they receive from s

173 Cell-mediated protection from liver-stage malaria relies on a sufficie

174 dothelial cells and that NRP1 contributes to protection from low-dose angiotensin II-induced increase

175 Moreover, a single dose conferred protection from lung disease in most of the vaccinated h

176 UC-3 F VLP-immunized dams showed significant protection from lung pathology and from induction of inf

177 heretofore of unknown function, affords self-protection from lysis by AmpDh3.

178 to 25.32 ng/mL) would ensure a 95% chance of protection from malaria parasite infection.

179 Host protection from malaria relies on immune-driven resistan

180 d B-cells, which may contribute to postnatal protection from malaria.

181 udies assume that the serologic correlate of protection from measles disease is 120 mIU/mL.

182 ) nAb titer of ~1:500 afforded more than 90% protection from medium-dose SHIV infection.

183 In addition, the extent of protection from methylation damage conferred by dsDNA re

184 f STIM2 results in lower cytokine levels and protection from mortality in a mouse model of systemic i

185 dentify global baseline immune correlates of protection from mortality to virus infection.

186 papaverine and zolpidem provided significant protection from multiple pathophysiological features, an

187 t the HA head and stalk were associated with protection from naturally acquired human influenza virus

188 Our data reveal that protection from neuroinvasion and disease is multifactor

189 eous thin films (down to 3 mum) that provide protection from O(2) while achieving highly efficient ca

190 mice that induces gammadeltaT cell-mediated protection from opportunistic infection.

191 these studies are truly the genes conferring protection from or risk of disease but also to define th

192 duced lung pathology and provided 60 to 100% protection from otherwise lethal infection.

193 lear adaptation to elevated sound levels and protection from overstimulation.

194 tion, nucleic acid synthesis, apoptosis, and protection from oxidative damage.

195 Besides having higher alpha-tocopherol protection from oxidative phenomena, EVOOs with the high

196 ers an advantage to the organism in terms of protection from oxidative stress and ensuring the acquis

197 One possibility is protection from oxidative stress by glucose-6-phosphate

198 reveals mechanisms for iron accumulation and protection from oxidative stress, necessary for mitochon

199 lar and cellular basis of CPS-induced immune protection from P. falciparum infection.

200 form, resulting in inhibition of PARP-1 and protection from PARP-1-dependent cell death.

201 tion during chronic infection and subsequent protection from pathogenic SIV challenge.

202 e impact on control of virus replication and protection from pathogenic SIVmac239 challenge.

203 ll recognition of specific antigens mediates protection from pathogens and controls neoplasias, but c

204 a microbial ecosystem on the skin, including protection from pathogens and tuning of the skin microen

205 sentinels that are essential for early host protection from pathogens at initial sites of infection.

206 le in detoxification from silver nitrate and protection from pathogens for the bacterium and potentia

207 ealth in various ways like prebiotic effect, protection from pathogens, anti-inflammatory activity an

208 ed to beneficial outcomes in infants through protection from pathogens, modulation of the immune syst

209 ent and maintenance of barrier function, and protection from pathogens.

210 pressed inhibitory receptors associated with protection from PD clinical features in the presence of

211 , which is the primary in vitro correlate of protection from placental malaria.

212 fection in pregnancy and are associated with protection from placental malaria.

213 icted secondary structures that could afford protection from plasma nucleases.

214 s may harbor a modest but important level of protection from postnatally acquired ZIKV for several mo

215 t this mechanism may have evolved to provide protection from potentially harmful types of environment

216 ps is an adaptive behaviour that can provide protection from predators, improve foraging and facilita

217 addition to epidemiological factors, limited protection from preexisting immunity against IDVs in cat

218 We demonstrate that these hydrogels provide protection from preservation techniques (including lyoph

219 nd southern Europe, but these require urgent protection from proposed dam developments.

220 les of which have been broadly attributed to protection from proteolysis, as the extracellular milieu

221 proved the bioactivity of IL-12 and provided protection from proteolytic cleavage in-vitro.

222 proteins that confers key advantages such as protection from proteolytic degradation, altered solubil

223 rix protein cyclophilin D (CypD) show robust protection from PVI dysfunction following perinatal NMDA

224 VIT in cMCD patients, as it correlates with protection from re-stings.

225 However, this was not due to MANF-mediated protection from reactive oxygen species generated during

226 In P. aeruginosa, a primary mechanism for protection from redox stress is the antioxidant glutathi

227 larly small ranges that currently receive no protection from regulatory programs designed to prevent

228 epatitis B virus (HBV) infection and acquire protection from reinfection as conferred by vaccination.

229 ed SARS-CoV-2 mutant D614G, suggesting cross-protection from reinfection by either strain.

230 well as their potential to provide long-term protection from reinfection with SARS-CoV-2, remains deb

231 (durability of antibodies and necessity for protection from reinfection), seropositive test results

232 als during previous infection correlate with protection from reinfection, suggesting that an effectiv

233 l be maintained or whether they will provide protection from reinfection.

234 Memory B cells (MBCs) are key for protection from reinfection.

235 upplemental sodium acetate exhibited similar protection from rejection, and subsequently demonstrated

236 Inhibition of MMP13 abrogated the protection from renal fibrosis afforded by macrophage Tw

237 ry cell formation and rapid responses to and protection from repeat infections.

238 e challenged with a Western diet, indicating protection from resection-induced liver failure.

239 gregates with rPrP and thereby gains partial protection from RNase digestion.

240 did not alter IgA responses associated with protection from rotavirus disease.

241 ng pathway that is required for EPS-mediated protection from S. aureus infection in vivo We conclude

242 to enhance immunogenicity to provide better protection from seasonal influenza virus infection and i

243 meras with IRF3-KO bone marrow showed little protection from sepsis, whereas chimeras with IRF3-KO st

244 ater plasma bactericidal activity and longer protection from seroconversion.

245 health implications of a plausible BCG cross-protection from severe COVID-19 are discussed.

246 or a potential biological basis of BCG cross-protection from severe COVID-19, and refine the epidemio

247 ablish causality between BCG vaccination and protection from severe COVID-19.

248 demonstrates that CD8+ T cells contribute to protection from severe dengue virus (DENV) disease and v

249 Th2 in transplant patients appears to confer protection from severe influenza infection, independent

250 bind a discrete PfEMP1 subset associate with protection from severe malaria and predict future risk.

251 dly neutralizing Ab-mediated (BnAb-mediated) protection from simian-human immunodeficiency virus (SHI

252 ing organelles that provide pigmentation and protection from solar UV radiation to the skin.

253 Whether the variant confers protection from specific risk factors for liver disease

254 ) family of chaperones are the front line of protection from stress-induced misfolding and aggregatio

255 genetic complexes to support growth, provide protection from stresses, mediate morphogenesis, and/or

256 Interestingly, in spite of the protection from structural articular cartilage damage, t

257 lowed by reperfusion, confers cardiovascular protection from subsequent ischaemic bouts.

258 tory cytokine production was associated with protection from subsequent Pf infection, but also with a

259 This cocktail, RIID F6-H2, provided protection from SUDV infection in rhesus macaques when a

260 ng PLZF(lo)RORgammat(lo) iNKT1 cells provide protection from symptomatic ocular herpes.

261 This is correlated with a protection from TAC-induced cellular Ca(2+) signaling al

262 ate a novel locus that confers male-specific protection from tau pathology and highlight the value of

263 ory mucosa has been shown to promote greater protection from TB in animal models.

264 mechanisms that provides multiple layers of protection from the carryover of mitotic chromosome segr

265 bscopal immunotherapeutic effect measured as protection from the challenge tumor and durable splenocy

266 cular risk, metabolism, and mental health in protection from the cognitive consequences of neuropatho

267 In plants, sinapate esters offer crucial protection from the deleterious effects of ultraviolet r

268 Host cells provide protection from the environment for intracellular pathog

269 es both physical integrity and immunological protection from the external environment using functiona

270 rom the disease and on the correlates of the protection from the future exposures.

271 tivation of this pathway in females triggers protection from the negative impact of males.

272 thesized that the CNS parenchyma may acquire protection from the reactive astrocytic Glia Limitans no

273 mechanical allodynia, they did not show any protection from the small-fiber neuropathy.

274 Not accounting for protection from the use of ITNs during pregnancy, expand

275 ecipients suggests a lack of strain-specific protection from the vaccine.

276 associated SNPs that truncate SLC30A8 confer protection from this disease, contradicting this explana

277 Protection from TNF-induced apoptosis depended on ST6Gal

278 Protection from TnI-directed autoimmune heart pathology

279 insect midgut and has roles in digestion and protection from toxins.

280 1) deletion exhibited substantially enhanced protection from tumor rechallenge and sensitivity to ant

281 ly or intravenously mediate antigen-specific protection from tumor rechallenge, both in the brain and

282 from 30% of the mice, and conferred curative protection from tumor rechallenges, consistent with immu

283 act social behavior, predator avoidance, and protection from ultraviolet irradiation.

284 arasitic exploitation, thermoregulation, and protection from ultraviolet light, microbes, and abrasio

285 RNase 7 humanized mice exhibited marked protection from UPEC.

286 nt are enriched in functions associated with protection from UV and high-light intensity and the gene

287 pomegranate consumption may lead to enhanced protection from UV photodamage.

288 ematically the literature on "herd"/indirect protection from vaccinating children aged 6 months to 17

289 are required to better quantify the indirect protection from vaccinating children for different setti

290 Protection from vaccination is believed to be mediated b

291 ntation and is an effective way to reinstate protection from various pathogens (eg, influenza virus a

292 es are largely known for their innate immune protection from viral infections.

293 for glucose stimulated insulin secretion for protection from viral lysis.

294 Thus, protection from viremia is considered essential for prev

295 apparatus and provide cell-type-independent protection from virus infection.

296 Protection from virus shedding and viremia during challe

297 insecticidal activity and significant plant protection from WCR damage.

298 adeltaKO mice exhibit decreased food intake, protection from weight gain on standard and high-fat die

299 Protection from yearly recurring, highly acute infection

300 n 6 (IFI6) as genes providing high levels of protection from ZIKV.