ライフサイエンスコーパス: protein microarray

1 nt with this compound by using reverse-phase protein microarray.

2 PR and MS detection on a single high-content protein microarray.

3 cinia virus, as determined by vaccinia virus protein microarray.

4 y, immunohistochemistry, DNA microarray, and protein microarray.

5 orescence assay (IFA) were screened by human protein microarray.

6 ys, including a central nervous system (CNS) protein microarray.

7 biota antigens was assessed by using a novel protein microarray.

8 n human sera on a genome level B. melitensis protein microarray.

9 to 5 avian influenza virus antigens, using a protein microarray.

10 targets were identified by immunoscreening a protein microarray.

11 ase were used to verify the formation of the protein microarray.

12 used recombinant Pak2 to screen high density protein microarrays.

13 nflammatory biomarkers were quantified using protein microarrays.

14 the majority of yeast protein kinases using protein microarrays.

15 dentification of nonspecific interactions on protein microarrays.

16 a with 8027 recombinant human proteins using protein microarrays.

17 ontrol of printed cDNA, oligonucleotide, and protein microarrays.

18 a combination of mass spectrometry (MS) and protein microarrays.

19 a from cancer cell lines using reverse-phase protein microarrays.

20 ur the development of the next generation of protein microarrays.

21 te the functionality of so-called functional protein microarrays.

22 cations and, in particular, for constructing protein microarrays.

23 TCH3 terminating at Asp964 was used to probe protein microarrays.

24 t assays (ELISA), neutralization assays, and protein microarrays.

25 graphic locations.METHODSUsing multipathogen protein microarrays, 878 milk and 94 paired serum sample

26 d from joint immune complexes were tested on protein microarrays against a range of candidate autoant

27 urther screened 593 full-length human TFs on protein microarrays against different nucleosome sequenc

28 and out as most promising for utilization in protein microarrays, albeit both have been used only spo

29 Protein microarray analyses revealed a number of protein

30 immunoglobulin reactivity data obtained from protein microarray analyses; and (ii) known protective a

31 A reverse-phase protein microarray analysis and Western blotting reveale

32 resented method is particularly relevant for protein microarray analysis because it is label-free, si

33 Here, we present the single-channel Protein Microarray Analysis Pipeline, a tailored computa

34 stem cells in breast tumors, we conducted a protein microarray analysis that identified the histone

35 e profile of the functions regulated by this protein, microarray analysis was used to examine transcr

36 s study developed a human coronavirus (HCoV) protein microarray and included all seven human coronavi

37 Protein microarray and pulldown experiments revealed tha

38 ific antibody reactivities using a multi-AdV protein microarray and serum from a Bangladeshi birth co

39 We used a protein microarray and subsequent sequential enzyme-link

40 is of proteins in plants we have developed a protein microarray and used it to study the global analy

41 We have used protein microarrays and autoantibodies from cancer patie

42 al detection is well suited for high-content protein microarrays and comprehensive protein analysis-f

43 rved on the microarray was double-checked by protein microarrays and confirmed by aptamer-baited co-i

44 , thereby increasing the quality of spots in protein microarrays and especially improving screening t

45 gainst a panel of >8000 human antigens using protein microarrays and fluorescence detection.

46 roteomic and genomic levels with multiplexed protein microarrays and high-throughput DNA sequencing.

47 utilizes active mammalian cell extracts and protein microarrays and identified 1,500 potential subst

48 , flow cytometry based single-cell analysis, protein microarrays and interaction studies.

49 verexpressing STPB-C which were studied with protein microarrays and other techniques, direct examina

50 We used protein microarrays and quantitative fluorescence polari

51 A combination of protein microarrays and two-dimensional liquid-phase sep

52 the camels for IgG immunofluorescence assay, protein microarray, and virus neutralisation assay.

53 ion of protein expression by "reverse-phase" protein microarray; and (e) prospective validation of ca

54 parallel array of microfluidic channels for protein microarray applications.

55 The protein microarray approach revealed radiation-induced u

56 activity, respectively) was assessed using a protein microarray approach.

57 Protein microarrays are a powerful tool for ACAA detecti

58 iquid chromatography, mass spectrometry, and protein microarrays are among the proteomic tools availa

59 Multiplexed immunoassays on antibody-based protein microarrays are an attractive solution for analy

60 Protein microarrays are an emerging technology for study

61 Protein microarrays are emerging as an important means o

62 Protein microarrays are fabricated from double-stranded

63 Here we demonstrate that functional protein microarrays are particularly well-suited for hig

64 Protein microarrays are the format of choice for high-th

65 The protein microarrays are useful for determining the compl

66 Protein microarrays are valuable tools for high-throughp

67 put project for identification of KSRs using protein microarrays, as well as known KSRs curated from

68 using a continuous titer measurement from a protein microarray assay.

69 Compared with protein microarrays assayed with the conventional incuba

70 Protein microarray assays revealed a burst of autoimmuni

71 ion in in situ signal amplification, DNA and protein microarray assays, single nucleotide polymorphis

72 NA interaction data for humans identified by protein microarray assays.

73 Protein microarray assessed the differential expression

74 bodies are strongly protection-associated by protein microarray assessment.

75 , we efficiently fabricated both peptide and protein microarrays at relatively high density.

76 We probed the Arabidopsis protein microarray AtPMA-5000 with the N-terminal cytopl

77 We describe here 3-D protein microarrays based on nanopore alumina membranes

78 We developed a high-density self-assembling protein microarray, based on the nucleic acid programmab

79 integrating phosphoproteomic data with human protein microarray-based AKT1 kinase assays, we discover

80 Here, we describe a protein microarray-based approach to investigate determi

81 Here, we used a protein microarray-based approach to systematically surv

82 mputational prediction was validated using a protein microarray-based approach.

83 We benchmarked the protein microarray-based assay against a set of known qu

84 , we have used a combined bioinformatics and protein microarray-based strategy to systematically char

85 repertoire of MS blood and CSF, followed by protein microarray-based testing of recombinantly expres

86 vant expression vector and used to produce a protein microarray by transcribing, translating, and cap

87 We generated protein microarrays by printing complementary DNAs onto

88 ave demonstrated proof of the concept that a protein microarray can type whole blood and detect antib

89 esign approaches, the overall performance of protein microarrays can be compromised by diffusion-limi

90 We show that protein microarrays can serve as a rapid, sensitive, and

91 Protein microarray chips are probed with sera from indiv

92 Reverse-phase protein microarrays combined with Western blotting revea

93 A B. melitensis protein microarray comprised of nearly all proteins enco

94 Here we use protein microarrays comprising virtually every Src homol

95 orophore-conjugated antibody and tested on a protein microarray configuration with good sensitivity a

96 ELISA assays and protein microarrays constructed with double-His6 GFP dem

97 vide insight into this area, we fabricated a protein microarray containing 1,205 Burkholderia pseudom

98 Here we used a protein microarray containing 2,724 Salmonella enterica

99 Using the DUB Chip, a protein microarray containing 35 DUBs, we demonstrate a

100 To this end, we developed a protein microarray containing approximately 23% of the P

101 ce was estimated using a validated multiplex protein microarray containing NS1 proteins for 11 flaviv

102 6 serum samples (16 iCCAs and 10 CTRs) using protein microarrays containing 1622 functional proteins.

103 Here, we used protein microarrays containing hundreds of variants of t

104 nses were analyzed longitudinally using a Pf protein microarray covering 91% of the proteome, providi

105 We probed protein microarrays covering 824 unique P. falciparum pr

106 An important application of protein microarray data analysis is identifying a serodi

107 rential analysis workflow for single-channel protein microarray data in form of an R script and web a

108 array, the majority of the valuable original protein microarray data is still not publically accessib

109 d on an external pathogen proteome for which protein microarray data were obtained after the initial

110 s very well when tested against experimental protein microarray data.

111 fically designed for archiving and analyzing protein microarray data.

112 in a comprehensive analysis report for their protein microarray data.

113 To address this issue, we constructed Protein Microarray Database (PMD), which is specifically

114 tective antigens when trained using only the protein microarray datasets.

115 9 patients and 36 healthy patients, the HCoV protein microarray demonstrated 97% sensitivity and 97%

116 Protein microarray demonstrated that inhibition of media

117 f human serum from 166 individuals via human protein microarrays demonstrates that IgG autoantibodies

118 The multiplex protein microarray developed at Vibrant was designed to

119 Protein microarray development is absolutely dependent u

120 ion and dehydration problems associated with protein microarray development.

121 Using a custom protein microarray displaying 515 Pv antigens, we found

122 Besides to protein microarrays, DNA microarrays were also developed

123 h as kinase assays using modified kinases or protein microarrays, enables rapid kinase substrate iden

124 tational tool for analysis of single-channel protein microarrays enabling biomarker identification, i

125 Protein microarray experiments revealed that more than 1

126 Protein microarrays exposed to cellular extracts could o

127 ods to assess the quality and performance of protein microarrays fabricated from undefined protein co

128 The approach uses high-density protein microarrays fabricated using nucleic acid progra

129 The most challenging step in protein microarray fabrication is high-throughput produc

130 This convenient on-chip protein microarray fabrication method can be implemented

131 Our results showed that serum factor protein microarrays facilitate detection of autoantibody

132 rs, we aim to build a multiplexed Flavivirus protein microarray (Flaviarray) that includes all of the

133 retrospectively processed using a commercial protein microarray fluorescent test.

134 oactivators in solution FRET experiments and protein microarray fluorometric and FRET assays.

135 unbiased manner, we constructed a multiplex protein microarray for detection of serum factor-binding

136 mpact PEL cell survival, we screened a human protein microarray for ERK-primed GSK-3 substrates.

137 A protein microarray for the early stage diagnosis of seps

138 assessed the sensitivity and specificity of protein microarrays for ACAA identification and discover

139 We employ plasmonic protein microarrays for the early detection of a cancer

140 uses for our approach: as an alternative to protein microarrays for the identification of drug targe

141 ly relevant concentrations of TNF-alpha in a protein microarray format that can be expanded to multip

142 tection of a panel of cancer biomarkers in a protein microarray format.

143 As an example, we interrogated a protein microarray formed by a commercial drop-on-demand

144 The current technology for protein microarrays has been derived primarily from DNA

145 The development of peptide and protein microarrays has created enormous opportunities i

146 In the short term, protein microarrays have a greater potential to impact d

147 DNA and protein microarrays have become an established leading-e

148 Protein microarrays have been successfully used for dete

149 Protein microarrays have demonstrated to be cost-effecti

150 Protein microarrays have emerged as an indispensable res

151 vents, measured by time-series reverse-phase protein microarrays, high-content imaging, and flow cyto

152 Protein microarray identified 366 non-HLA antibodies (>1

153 rofile of 280 cytokines using a quantitative protein microarray in 12 ACS patients and 16 healthy con

154 we evaluated responses to 856 Pf antigens by protein microarray in 186 Ugandan children, for whom det

155 Spectra have been obtained from protein microarrays in a high throughput process.

156 and approximately 5,000 human proteins using protein microarrays in an attempt to better understand t

157 dy production was assessed using autoantigen protein microarrays, including a central nervous system

158 nized 1547 proteins present on a large-scale protein microarray, indicating polyreactivity.

159 Protein microarray is a powerful technology for both bas

160 Overall, the HCoV protein microarray is multiplexed, sensitive, and specif

161 Protein microarray is one of the best platforms to profi

162 IA057, NCT03300050) using an influenza virus protein microarray (IVPM).

163 Furthermore, a survey of recent protein microarray literature reveals that an even wider

164 Using a protein microarray made up of 1920 elements (146 distinc

165 Protein microarrays may be useful in the search for mala

166 al genomic data while new data types include protein microarray, metabolic pathways, compounds, quant

167 ed imaging reflectometry (AIR), a label-free protein microarray method.

168 ed P. aeruginosa PAO1 proteins by a modified protein microarray methodology called the nucleic acid-p

169 exchange averaged nearly 70%, quantified by protein microarray of individual trabeculae.

170 We have produced protein microarrays of a near-complete vaccinia proteome

171 PA can analyze hundreds (even thousands on a protein microarray) of proteins in a single experiment,

172 fied 31 substrate hits for WWP2(Y369E) using protein microarrays, of which three were known autophagy

173 Protein microarrays offer a high-throughput method for d

174 Here we present protein microarrays on a novel nanostructured, plasmonic

175 dentification of the factors that impact the protein microarray patterns, these studies usually have

176 tforms (planar and bead array, reverse phase protein microarray, phosphoflow, AQUA and mass spectrome

177 pathic SFN (iSFN) by a novel high-throughput protein microarray platform that captures autoantibodies

178 We developed a new protein microarray platform that utilizes a filtration a

179 za viruses in the general population using a protein microarray platform.

180 Protein microarrays presenting spots of collagen and lip

181 atform that utilizes a filtration assay with protein microarrays printed on protein-permeable nitroce

182 Protein microarray profiling identified the adaptor TAB1

183 odium falciparum malaria were analyzed using protein microarrays (Protoplex Immune Response Assay, Th

184 eins for ovarian cancer and demonstrate that protein microarrays provide a powerful approach to ident

185 Protein microarrays provide a powerful tool for the stud

186 Protein microarrays provide an efficient way to identify

187 Protein microarrays represent an emerging technology tha

188 We used a protein microarray representing 491 P. falciparum protei

189 Protein microarray results were validated by using an in

190 assays using recombinant Erk3 confirmed the protein microarray results, and phospho-specific antiser

191 A bead-based assay was used to validate protein microarray results.

192 NK-cell cytotoxicity assays and protein microarrays reveal novel biomarkers of NK cell-m

193 Melanoma protein microarrays revealed a correlation between NKmK

194 atients using native protein and recombinant protein microarrays revealed unique disease-specific, hu

195 igh-throughput screening approach based on a protein microarray reveals that many human transcription

196 We tested this hypothesis with reverse-phase protein microarrays (RPA) for multiplexed cell signaling

197 Using reverse-phase protein microarrays (RPMAs), we evaluated the activation

198 Reverse-phase protein microarrays (RPPAs) are a useful platform for id

199 nd hippocampus was measured by reverse phase protein microarray (RPPM).

200 A human protein microarray screen identified direct SNORD50A and

201 In this work we used a protein microarray screen to identify the Rac-specific G

202 Starting from an unbiased protein microarray screen, we identified a set of lipopr

203 Protein microarray secretome analyses revealed angiogeni

204 The HCoV protein microarray showed high reproducibility and sensi

205 econdary structure prediction is as good for protein microarray spectra as for the reference attenuat

206 We combined here the use of protein microarrays spotted at a density of ca 2500 samp

207 ughput and multiplexing of T cell detection, protein microarrays spotted with defined p/MHC complexes

208 ectroscopy kinetic and equilibrium analyses, protein microarray studies, and I-TASSER structural mode

209 ne the most important tenets of a functional protein microarray such as covalent attachment, native p

210 re, we developed a multiplexed spike variant protein microarray (SVPM) and utilized it for quantifyin

211 A protein microarray system containing different dilutions

212 Through the use of a chimaeric protein microarray system together with sera from a pane

213 arkers for Lyme disease are measured using a protein microarray system, Lyme Immunochip, in a single

214 nature of systemic adverse events, we used a protein microarray technique to precisely quantitate 108

215 gnals from a newly developed high-throughput protein microarray technique.

216 ging as specific protein capture reagents in protein microarray technologies.

217 rks, we used reverse-phase signaling pathway protein microarray technology and identified three signa

218 Here we use protein microarray technology and proteome-wide glycosyl

219 Here, we used protein microarray technology and the activated enzyme p

220 study were to (i) establish high-throughput protein microarray technology as a method to investigate

221 Finally, recent developments in protein microarray technology provide a versatile tool t

222 cial flat panel OLED display technology with protein microarray technology to enable high-density flu

223 Our results demonstrate that protein microarray technology, combined with the target

224 Using protein microarray technology, we identified RAD18 as an

225 substrates targeted by protein kinases using protein microarray technology.

226 ia patients and 40 healthy individuals using protein microarray technology.

227 acellular interaction screen) assay by using protein microarray technology.

228 sues, 3) ELISA against microbial Ags, and 4) protein microarrays testing reactivity against multiple

229 ult is the on-chip, cell-free synthesis of a protein microarray that can be used immediately for SPRI

230 performed a PAR-binding screen using a human protein microarray that covers most of the human proteom

231 ory syndrome (SARS) infection, a coronavirus protein microarray that harbors proteins from SARS coron

232 rological response was characterized using a protein microarray that measured IgG and IgA antibodies

233 ternative substrate for printing multiplexed protein microarrays that have greater sensitivity throug

234 ere is no database specifically tailored for protein microarray, the majority of the valuable origina

235 t injury are poorly characterized, we used a protein microarray to compare antibody repertoires in pr

236 We also used a protein microarray to demonstrate a postgenomic applicat

237 We developed a custom protein microarray to detect autoantibodies to both CNS

238 e JCI, Price and colleagues used a multiplex protein microarray to identify autoantibodies in serum f

239 We used a human protein microarray to identify the actin-regulatory prot

240 We investigated the potential of this protein microarray to screen for interactions between le

241 in chip ubiquitination screen using a human protein microarray to uncover putative substrates for th

242 e-cancer tissue, we developed and used phage protein microarrays to analyze serum samples from 119 pa

243 Here, we use protein microarrays to assess binding to >9,400 human pr

244 lobulinemia (WM), we employed antibody-based protein microarrays to compare patterns of protein expre

245 sed the activated MPKs to probe high-density protein microarrays to determine their phosphorylation t

246 of these changes in enzyme activity, we used protein microarrays to identify cell proteins that were

247 The use of protein microarrays to profile the autoAb response in PV

248 Using high-density protein microarrays to screen post-HSCT plasma, we ident

249 We used protein microarrays to serologically identify nucleolar

250 ause of the increasing use of biosensors and protein microarrays, two technologies that use protein i

251 ch the entire database by experimental name, protein microarray type, and sample information.

252 a biosensing unit, such as AMS, MALDI-MS or protein microarray-type biochips.

253 Our results further demonstrate that protein microarrays uncover a diverse set of interaction

254 nd were suitable for the printing of ordered protein microarrays used in protein-protein interaction

255 l be useful for a wide variety of functional protein microarray users.

256 the authors have created a highly sensitive protein microarray using the principle of single-molecul

257 Optimal conditions for depositing protein microarrays using a continuous-flow microfluidic

258 The analysis of self-assembled protein microarrays, using matrix-assisted laser desorpt

259 A Cryptosporidium protein microarray was constructed by in vitro transcrip

260 Reactivity to 21 PfEMP1 fragments on a protein microarray was measured in serum samples from Ma

261 An Epstein-Barr virus (EBV) protein microarray was used to screen for proteins bindi

262 Using this novel protein microarray we have longitudinally analysed the s

263 Using a protein microarray, we determined serologic responses to

264 -based test, a glycan and an allergen (glyco)protein microarray, we mapped IgE fine specificity among

265 Using reverse-phase protein microarrays, we identified a breast tumor protei

266 2 (FLS2) receptor using Arabidopsis thaliana protein microarrays, we identified the reticulon-like pr

267 Using these 65 antigens on protein microarrays, we trained neural networks on two-c

268 tive bioinformatics and Mycobacterium leprae protein microarrays were applied to investigate whether

269 linical applications of the filtration-based protein microarrays were demonstrated by detecting carci

270 Three applications for protein microarrays were demonstrated: screening for pro

271 Highly multiplexed protein microarrays were designed and fabricated.

272 Protein microarrays were exposed to these complex extrac

273 Protein microarrays were highly sensitive and specific f

274 Protein microarrays were prepared and screened with seve

275 Protein microarrays were printed onto poly(ethylene glyc

276 Protein microarrays were used to characterize designed,

277 Whole genome arrays and reverse phase protein microarrays were used to determine gene expressi

278 Protein microarrays were used to measure levels of anti-

279 To identify these pathways, protein microarrays were used to profile the phosphoryla

280 The array is then used to print a protein microarray, where each element contains the anti

281 identify methylated residues, as well as to protein microarrays, where they can be used to screen fo

282 method for identifying new substrates using protein microarrays, which can markedly expand the list

283 n, the combination of chimaeric proteins and protein microarrays will greatly facilitate the screenin

284 ptors against a highly diverse extracellular protein microarray with 686 genes represented.

285 We established a multiplex protein microarray with structural and non-structural no

286 vities targeted by SA, we probed Arabidopsis protein microarrays with a functional analog of SA.

287 demonstrate a method to create high density protein microarrays with excellent spot uniformity using

288 on the PEG net-cloth enables the creation of protein microarrays with high signal to noise ratio.

289 Probing of gonococcal protein microarrays with immune sera from the 2 groups i

290 By probing high-density protein microarrays with patient plasma, we discovered 3

291 study of small molecule binding kinetics on protein microarrays with plasmonic-based electrochemical

292 ue coupling the high-throughput potential of protein microarrays with the biologically relevant reado

293 od of manufacturing high-density multiplexed protein microarrays with the capacity to detect low leve

294 By combining the throughput of protein microarrays with the fidelity of fluorescence po

295 Fully functional protein microarrays, with monolayer arrangements and com