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1 ulates the excitation energy from the entire protein subunit.
2 ion modulating the allosteric network in the protein subunit.
3 bled from two mutant forms of the same basic protein subunit.
4 subunit, suggesting an interaction with this protein subunit.
5 receptor-binding GP1, and transmembrane GP2 protein subunits.
6 , the other half is actively exchanging core protein subunits.
7 subunits connected to the two different MoFe-protein subunits.
8 ed by the highly interlocked organization of protein subunits.
9 d of the long backbone helix of major capsid protein subunits.
10 the activity of endogenous heterotrimeric G protein subunits.
11 ifferences in (15)N incorporation into their protein subunits.
12 -based assay that monitors dissociation of G protein subunits.
13 ned by a conformational change in one of the protein subunits.
14 e diacylglycerol addition to GerD and GRs' C protein subunits.
15 wer of drift and the structural integrity of protein subunits.
16 ic8 strains have greatly reduced levels of G-protein subunits.
17 ts effects in the structural features of the protein subunits.
18 ional roles through their interaction with G-protein subunits.
19 as the ribosome, composed of many different protein subunits.
20 ae, OT is composed of nine integral membrane protein subunits.
21 aic virus (TMV) from its constituent RNA and protein subunits.
22 between distinct structural features on the protein subunits.
23 energy of association between the assembling protein subunits.
24 e complexes that contain no other detectable protein subunits.
25 his inner membrane complex is composed of 11 protein subunits.
26 onal interaction between biologically active protein subunits.
27 the composition of complexes formed by PBAF protein subunits.
28 liday junction (HJ) bound specifically by 11 protein subunits.
29 vage site (N(-4)) and the RNase P protein (P protein) subunit.
30 and mitochondria of a tiny minority of their protein subunits?
31 re, we demonstrate that the SARS-CoV-2 spike protein (subunit 1 and 2), but not the N protein, direct
32 Owing to its size and complexity (~1,000 protein subunits, ~110 MDa in humans), the NPC has remai
33 N translation and identified small ribosomal protein subunit 25 (RPS25), presenting a potential thera
34 itant loss of the mitochondrial acyl carrier protein subunit ACPM1 from the enzyme complex and paraly
35 ploying PSII microcrystals that retained all protein subunits after complete manganese removal and by
36 act to temporally modulate the activity of G protein subunits after G protein-coupled receptor activa
37 A (PRKACA) or the guanine nucleotide-binding protein subunit alpha (GNAS) gene, the CYP11B1 promoter
38 rin and Galpha13 (guanine nucleotide-binding protein subunit alpha 13), resulting in the constitutive
39 d Des1 mice, on a guanine nucleotide-binding protein subunit alpha transducin 1 knockout ( Gnat1(-/-)
40 evious work showed that the heterotrimeric G protein subunit alpha(q) contains a polybasic region in
41 Heterozygous missense mutations in coatomer protein subunit alpha, COPA, cause a syndrome overlappin
42 ways after allergen challenge and, through G-protein subunit alpha, ERK, and Pin1 signaling, likely p
44 ray and RNAi that guanine nucleotide-binding protein subunit alpha13 (Galpha13) is a negative regulat
46 pathways that are dysregulated in PDAC was G protein subunit alphai2, which has not been previously a
47 ith five copies of Gbetagamma in which the G-protein subunits also interact directly with one another
48 illustrating differential partitioning of G-protein subunits among stimuli with similar ultimate imp
49 s dependent on activation of the G(alpha)s G-protein subunit and cAMP-cAMP-dependent protein kinase a
50 that sequence-specific contacts between the protein subunit and the leader sequences of pre-tRNAs ma
53 ract with YbbN, including multiple ribosomal protein subunits and a strong interaction with GroEL.
55 ions with deletion mutations of both capping protein subunits and cofilin mutations with severing def
56 reased expression of mitochondrial complex I protein subunits and concomitant changes in glucose meta
57 ed but differing interactions between capsid protein subunits and each type of nucleotide in each of
58 involving a complex interplay between these protein subunits and IP6 that in turn controls nucleosom
59 ccurs with a substoichiometric ratio of coat protein subunits and is followed by a gradual increase i
60 isoforms are stimulated by heterotrimeric G protein subunits and members of the Rho GTPase family of
61 in the overall structure of the helices, the protein subunits and the location of the various cofacto
63 nique, unequal association of GIRK1/2 with G protein subunits, and the cooperative nature of GIRK gat
64 ssembly state or through the gain or loss of protein subunits, and these processes can be driven by b
65 x, yet do this by interacting with different protein subunits, and using steric or non-steric modes o
67 the 'pointed-end complex' that includes the protein subunits Arp11, p62 and the p27/p25 heterodimer.
68 form a 20-nm-diameter particle comprising 60 protein subunits, arranged with 532 symmetry when crysta
69 y of nucleus-encoded and chloroplast-encoded protein subunits as well as the insertion of hundreds of
70 atic interactions stabilize four betagamma G-protein subunits at the interfaces between four K(+) cha
72 tic islets, we investigated the effects of G protein subunit beta 5 (Gnb5) knockout on insulin secret
76 is considerable variation in PilA, the major protein subunit, both in amino acid sequence and in glyc
77 spectrometry (HRMS) were used to analyze the protein subunits (ca. 25-100 kDa) obtained after differe
78 leoprotein complex minimally consisting of a protein subunit called telomerase reverse transcriptase
80 i (T4P) are bacterial appendages composed of protein subunits, called pilins, noncovalently assembled
82 nsduction mutants; the heterodimeric capping protein subunit CAPZB and its partner TWF2 never concent
84 TtCmr complex, is composed of six different protein subunits (Cmr1-6) and one crRNA with a stoichiom
85 ricus, this complex is composed of seven CAS protein subunits (Cmr1-7) and carries a diverse "payload
87 e resulting amyloid fibrils, and the initial protein subunits composition, advancing our understandin
89 cleotides are bound asymmetrically by the Fe-protein subunits connected to the two different MoFe-pro
90 ound 61-nucleotide crRNA spans the entire 11-protein subunit-containing complex, where it interacts w
91 imate recombination of fragments that encode protein subunits could have quickly led to diversificati
92 s)) are composed of large complexes of multi-protein subunits creating ion channels in the cell plasm
93 2 solvent-accessible cysteines, resulting in protein subunits cross-linking, while maintaining its GS
96 vel chlamydia vaccine based on a recombinant protein subunit (CTH522) in a prime-boost immunisation s
97 clinical evaluation include live attenuated, protein subunit, DNA, and viral-vectored approaches.
102 haromyces cerevisiae Est3p and the catalytic protein subunit (Est2p) by demonstrating that recombinan
103 te the abundance of electron transport chain protein subunits expressed from both nuclear and mitocho
104 to precisely direct tRNA 3' end to the other protein subunit for aminoacylation in a conformation-dep
105 dulate the electrostatic interactions of the protein subunits for various association strengths.
106 us, triggering TLR2 with an antigen-specific protein subunit formulation is a possible strategy for t
107 2 double-stranded DNA genome is bound to one protein subunit from a connector complex that also forms
108 mic swelling, translocation of dissociated G-protein subunits from the disc membranes into the cytopl
109 ), bound NKB but impaired dissociation of Gq-protein subunits from the receptor compared with WT NK3R
110 nhibitors and a strong interactor with the G-protein subunit G alpha(o), localizes to retinal ON bipo
111 V2R, which signals through heterotrimeric G-protein subunit G(s) alpha, adenylyl cyclase 6, and acti
112 ntracellular domain and the heterotrimeric G-protein subunit Galpha(S), and demonstrate that Galpha(S
113 rotein, and by showing that heterotrimeric G-protein subunits Galpha (GPA1) and Gbeta (AGB1) interact
114 to NF-kappaB activation through recruiting G protein subunits Galphai and Galpha12 to activate PKCbet
115 covery of a signalling platform comprising G protein subunit, Galphai and GIV, its guanine exchange f
116 vomeronasal sensory neurons expressing the G protein subunit Galphai2 regulate male-male and infant-d
117 by using a conditional knockout mouse for G protein subunit Galphai2, which is essential for V1R sig
118 Putative functions of the heterotrimeric G-protein subunit Galphai2-dependent signaling include ion
121 C-73E RhoGEF-2 isoform is activated by the G-protein subunit Galphaq and is required for normal rates
122 on molecule-1 (PECAM-1) and heterotrimeric G protein subunits Galphaq and 11 (Galphaq/11) are junctio
123 on system to inactivate the heterotrimeric G protein subunit Gbeta and find that this acute perturbat
124 ular application of antibodies against the G protein subunit Gbeta and was mimicked by the myristoyla
125 signal transduction by the heterotrimeric G protein subunit Gbeta1 is essential for proper pLLP migr
126 ising pTyr-PAK1, Etk/Bmx, the heterotrimer G-protein subunits Gbeta1, Ggamma2, and/or Ggamma5, PAK-as
127 bfamily RGS proteins are stabilized by the G-protein subunit Gbeta5, such that the knockout of the Gn
128 on of phospholipase C-beta3 (PLC-beta3) by G protein subunits Gbetagamma and Galpha(q), the relevant
129 ation, we found that signaling mediated by G protein subunits Gbetagamma is required to regulate cell
130 s of AC5 N terminus (5NT) bind to purified G protein subunits (GDP-Galpha(s) and Gbetagamma) with app
131 s, we further establish the heterotrimeric G protein subunit Gnb5 as a PSD-95 complex partner at dend
132 ene, encoding the pan-neuronally expressed G-protein subunit GOA-1, with a degradation-tagged transge
133 n their interaction with and regulation of G protein subunits: group I, guanine nucleotide exchange f
135 diffraction data to 2.0-A revealed that each protein subunit harbors a hot dog-fold and that the TE6
136 previously solved C-protein structures, each protein subunit has two extra helices at the C-terminus,
138 he VAX003 and VAX004 trials of a recombinant protein subunit HIV-1 vaccine and in the Step study, we
139 triction-modification enzymes comprise three protein subunits; HsdS and HsdM that form a methyltransf
140 ndensin protein MukB and nucleoid-compacting protein subunit HU-alpha are essential for the well-mixe
141 tream of the regulatory IkappaB kinase-gamma protein subunit in the NF-kappaB signaling pathway, and
142 nted tool for assessing the involvement of G protein subunits in chemoattractant receptor function.
143 While investigating the roles of different G-protein subunits in modulating the oil content in Cameli
145 spholipase Cbeta (PLCbeta) is activated by G protein subunits in response to environmental stimuli to
146 ase in the level of mRNA encoding proteasome protein subunits in response to MG132 treatment and an i
147 urther show preferential usage of distinct G-protein subunits in the presence of an additional signal
149 prising 20 copies of the esterase trimer, 60 protein subunits in total, with overall icosahedral geom
151 aS incorporation at D(2S) coexpressed with G-protein subunits indicated significant bias for promotio
153 pected interactions such as heterotrimeric G protein subunit interactions and aquaporin oligomerizati
155 nding site serves to promote and stabilize G protein subunit interactions in the presence of competin
156 guanine nucleotide binding and hydrolysis, G protein subunit interactions, and/or serve as alternativ
160 uble-strand break intermediate in which each protein subunit is covalently linked to the target DNA s
165 nges involving cooperativity between the two protein subunits, it has been hypothesized that conforma
166 le FvGbb2 does not interact with canonical G protein subunits, it may associate with diverse proteins
168 e 20 equivalent capsomers (trimers of capsid protein subunits) leading to a stable, nearly complete p
169 e are cross-molecular interactions among the protein subunits linearly along the nucleocapsid to stab
170 Chemical shift analysis indicates that the protein subunits making up the fibril adopt a compact co
171 gh movement of a flexible loop in one of the protein subunits may represent a general mechanism for t
172 act of genomic RNA on the association of the protein subunits may therefore provide further insights
174 lex denoted as "Mnx" that includes accessory protein subunits MnxE and MnxF, with an estimated stoich
176 mma-secretase complex, as suppression of the protein subunit nicastrin with small interfering RNA (si
178 tion of the alpha4 nAChR and regulation of G protein subunit o, G protein regulated-inducer of neurit
180 bunit of Pol epsilon, known to bind the Psf1 protein subunit of CMG, allows stable synthesis with CMG
181 ns isp-1 gene encodes the Rieske iron-sulfur protein subunit of cytochrome c oxidoreductase (complex
182 the fimA and rgpA genes, encoding the major protein subunit of fimbriae and an arginine-specific pro
183 use binding site predictions on tubulin, the protein subunit of microtubules, with molecular docking
184 endent replication, but addition of the Dpb2 protein subunit of Pol epsilon, known to bind the Psf1 p
185 tion (D40H) in the POLR3E gene, coding for a protein subunit of Pol III, in a child with recurrent an
187 inciple, we show that fish deficient for the protein subunit of telomerase exhibit the fastest onset
188 reverse transcriptase (hTERT; the catalytic protein subunit of telomerase) is subjected to numerous
189 binds the oligomycin sensitivity-conferring protein subunit of the enzyme at the same site as the AT
190 Protein 6A (ACTL6A, BAF53a) is an important protein subunit of the SWI/SNF epigenetic chromatin regu
195 letion of (13)C and/or (15)N for one or more protein subunits of a complex can greatly simplify the m
196 press three yeast (Saccharomyces cerevisiae) protein subunits of DNA REPLICATION FACTOR A (RFA) were
197 e hypothesis is that expression of genes for protein subunits of energy-transducing enzymes must resp
198 tations in connexins (Cxs), the constitutive protein subunits of gap junction (GJ) intercellular chan
200 or mitochondrial function because it encodes protein subunits of the electron transport chain and a f
201 of all 13 mitochondrial DNA (mtDNA)-encoded protein subunits of the human oxidative phosphorylation
202 nant b and oligomycin sensitivity-conferring protein subunits of the mitochondrial F1FO ATP synthase.
205 oplast-localized proteins, such as ribosomal proteins, subunits of the RNA polymerase, and thylakoid
207 y, often focusing on the analysis of ~25 kDa protein subunits, offers the potential for complete sequ
210 unted for by the incorporation of additional protein subunits or RNA rather than PRC2 dimerization.
211 ination with higher protein content, certain protein subunits or their polypeptides can also be targe
212 h AMPARs (via transmembrane AMPAR regulatory protein subunits) or NMDARs [via glutamate ionotropic re
213 ically active RNA subunit (PRNA) and a small protein subunit (P protein), catalyzes the 5'-end matura
215 otoinactivation outran the clearance of PSII protein subunits, particularly in cells grown at sub- or
216 tility, and biofilm formation, and the major protein subunit, PilA, is a promising vaccine candidate.
217 of attachment proteins and a trio of fusion protein subunits play the cell entry concert of parainfl
218 of the single RNA with four previously known protein subunits (POP5, RPP21, RPP29, and RPP30), we sho
219 etase is made of four integral transmembrane protein subunits: presenilin (PS), nicastrin, APH1, and
221 roscopy analyses of the Salmonella inner rod protein subunit PrgJ we present evidence that the assemb
222 tory (Galphai2) and stimulatory (GalphasL) G-protein subunits produced minor atrophic and hypertrophi
223 ically impact relative amino acid or storage protein subunit profiles; and (3) glutamine supply contr
224 of activators that includes heterotrimeric G protein subunits, protein tyrosine kinases, small G prot
225 ~500-kDa complex that contains 12 different protein subunits, providing many possible surfaces for i
226 es and functions by utilizing a few types of protein subunit quasi-equivalently at distinct geometric
227 The Mu wedges are comprised of only three protein subunits rather than the seven found in the equi
228 o using their respective constituent RNA and protein subunits, recognize and cleave such substrate-EG
229 mechanistic target of rapamycin complex 1/2 protein subunit regulatory associated protein of the MTO
231 local environment of the iron-sulfur (Fe/S) protein subunit residing in the Q(o) site on the other (
234 ary fibrosis disrupt the binding between the protein subunit reverse transcriptase of the telomerase
235 expression of the large and small ribosomal protein subunits (RPL and RPS, respectively) in hyperamm
237 cross glioma cell lines, revealing ribosomal protein subunit RPS11, 16, and 18 as putative biomarkers
239 has been to design interactions between the protein subunits so that they specifically assemble into
240 wo protein domains is important to allow the protein subunits sufficient freedom to assemble into the
241 ce appendages primarily composed of a single protein subunit termed pilin, which is encoded by pilA i
242 AP regions of the human telomerase catalytic protein subunit TERT into the mouse TERT backbone is suf
243 ome editing approaches to target BRCC36, the protein subunit that confers the BRCA1-A complex its DUB
245 in the RNA-binding domain of Srp54, the SRP protein subunit that directly interacts with helix 8.
246 ne, only in the presence of BSSbeta, a small protein subunit that forms a tight complex with BSSalpha
247 named gerWB) is shown to encode a receptor B-protein subunit that interacts with the GerUA and GerUC
250 During assembly of the bacterial flagellum, protein subunits that form the exterior structures are e
251 the tertiary structures of both gp7 and gp10 protein subunits that form the T = 7 icosahedral lattice
252 mer epitope (EDE), that bridges two envelope protein subunits that make up the 90 repeating dimers on
253 olymer network was fully cross-linked across protein subunits that make up the cage and extended the
254 is displayed along a helical arrangement of protein subunits that protect the crRNA from degradation
257 subunit, the telomerase RNA and a catalytic protein subunit, the telomerase reverse transcriptase (T
258 e, but the molecular function of their major protein subunits, the BAR domain-containing proteins Pil
259 an GIRK2 channel in complex with betagamma G-protein subunits, the central signalling complex that li
260 vity of SERCA is regulated by small membrane protein subunits, the most well-known being phospholamba
262 ion apparatus in its base that pumps certain protein subunits through the growing structure to their
263 o occur by the sequential addition of capsid protein subunits to a nucleus, with the final step compl
264 recruiting and organizing multiple copies of protein subunits to form a closed shell for genome packa
265 a surprisingly unrestricted ability of the G-protein subunits to form heterotrimeric complexes, inclu
266 ands of the DNA template and three dedicated protein subunits to trigger the highly controlled releas
267 ons of the entire structure consisting of 31 protein subunits together with solvent molecules contain
268 e P22, hydrophobic interactions peg the coat protein subunits together within a capsomer, where the E
270 governing the differential proteolysis of RC protein subunits under divergent cellular conditions.
271 nificant change in the orientation between G protein subunits upon activation that allows the G prote
273 The MF59-adjuvanted glycoprotein B (gB) protein subunit vaccine (gB/MF59) is the most efficaciou
274 ine these traits to create a three-component Protein Subunit vaccine on Microneedle Arrays (PSMNs) fo
276 sought to generate and evaluate recombinant protein subunit vaccines against C. burnetii To accompli
278 live vaccines, tetravalent DENV envelope (E) protein subunit vaccines are likely to stimulate balance
280 bcutaneous immunization of C57BL/6 mice with protein subunit vaccines containing one or two of these
282 ated vaccines present safety challenges, and protein subunit vaccines induce primarily antibody respo
285 n previously investigated as an adjuvant for protein subunit vaccines; here we optimize the CAFs for
286 lated proteins such as 50S and 30S ribosomal protein subunit variants and elongation factors were pos
287 ing mice deficient in individual Galphai/o G-protein subunits, we demonstrate that Galphai1 and Galph
290 a sets, whereas the models of the individual protein subunits were validated adopting the best practi
291 activation of an EGFP-tagged L10a ribosomal protein subunit, which allows translating ribosome affin
292 veal the C-terminal region of the small coat protein subunit, which is essential for virus assembly a
293 ignificant changes to the profile of storage protein subunits, which may have contributed to the impr
294 of a large number of symmetrically organized protein subunits whose local movements can be essential
295 in diameter, and is composed of thousands of protein subunits with a combined mass of approximately 2
296 ded by mass spectrometry, we build all known protein subunits with associated N-linked glycans and id
297 cetylcholine (M3-ACh) receptor as well as Gq-protein subunits with high spatiotemporal resolution in
298 n mitochondria is an L-shaped assembly of 44 protein subunits with one arm buried in the inner membra
299 composed of helically arranged single pilin-protein subunits, with a unique biomechanical ability to