ライフサイエンスコーパス: protein tyrosine phosphatase

1 es a strong T-cell regulator called lymphoid protein tyrosine phosphatase.

2 /mammalian target of rapamycine pathway, and protein tyrosine phosphatase.

3 HP2 is an ubiquitously expressed cytoplasmic protein tyrosine phosphatase.

4 oxidation that underlies redox inhibition of protein tyrosine phosphatases.

5 ype for a novel class of eukaryotic aspartyl protein tyrosine phosphatases.

6 y high conservation of the active site among protein tyrosine phosphatases.

7 phosphatase Src homology 2 domain-containing protein tyrosine phosphatase 1 (Shp1) show increased leu

8 Sorafenib and SC-1 activated Src-homology protein tyrosine phosphatase-1 (SHP-1) and STAT3 inhibit

9 ion between Src homology 2 domain-containing protein tyrosine phosphatase-1 (SHP-1) and VEGF-R2, whic

10 late radial migration in mouse brain via the protein tyrosine phosphatase 1B (PTP1B) and alpha- and b

11 aling and reduced levels of the phosphatases protein tyrosine phosphatase 1B (PTP1B) and phosphatase

12 We identified protein tyrosine phosphatase 1B (PTP1B) as a major targe

13 Protein tyrosine phosphatase 1B (PTP1B) is a ubiquitousl

14 Protein tyrosine phosphatase 1B (PTP1B) is a validated t

15 at increased NO production via inhibition of protein tyrosine phosphatase 1B (PTP1B) is associated wi

16 Protein tyrosine phosphatase 1B (PTP1B) is implicated in

17 e we show how these pillars are connected in Protein Tyrosine Phosphatase 1B (PTP1B), a drug target f

18 tion machinery modulates an interaction with protein tyrosine phosphatase 1B (PTP1B), an ER-associate

19 mally disruptive optical approach to control protein tyrosine phosphatase 1B (PTP1B)-an important reg

20 of Ca2+/calpain and resulting activation of protein tyrosine phosphatase 1B (PTP1B).

21 we examine the catalytic loop in the enzyme protein tyrosine phosphatase 1B (PTP1B).

22 Application of this strategy to protein tyrosine phosphatase 1B and a peptidyl-prolyl ci

23 ory power of these phenolic extracts against Protein Tyrosine Phosphatase 1B enzyme (PTP-1B), overexp

24 equired functionally active A1AT protein and protein tyrosine phosphatase 1B expression.

25 we experimentally validate a cryptic site in protein tyrosine phosphatase 1B using a covalent ligand

26 o enzyme inhibition (glycogen phosphorylase, protein tyrosine phosphatase 1B) or by inhibiting renal

27 T receptor activation through recruitment of protein tyrosine phosphatase 1B.

28 Here, we report that protein tyrosine phosphatases 1B (PTP1B) directly dephos

29 s zinc transport into hepatocytes to inhibit protein-tyrosine phosphatase 1B (PTP1B) activity, which

30 epatocytes with or without expression of the protein-tyrosine phosphatase 1B (PTP1B) and in wild-type

31 Neuronal protein-tyrosine phosphatase 1B (PTP1B) deficiency in mi

32 ficiency led to abnormally increased hepatic protein-tyrosine phosphatase 1B (PTP1B) expression and e

33 h as silencer of cell signaling 1 (SOCS1) or protein-tyrosine phosphatase 1B (PTP1B) in this process.

34 Protein-tyrosine phosphatase 1B (PTP1B) is a physiologic

35 Protein-tyrosine phosphatase 1B (PTP1B) is the canonical

36 Protein-tyrosine phosphatase 1B (PTP1B) regulates food i

37 Inflammation activates the protein-tyrosine phosphatase 1B (PTP1B), and this could

38 tor-kappaB (NF-kappaB)-mediated induction of protein-tyrosine phosphatase 1B (PTP1B).

39 osphotyrosine (pY) under the assistance of a protein tyrosine phosphatase-1B (PTP-1B).

40 Protein tyrosine phosphatase-1B (PTP1B) negatively regul

41 o studies have indicated that SH2-containing protein tyrosine phosphatase 2 (SHP-2) is a signaling fa

42 progenitor cells deficient in SH2-containing protein tyrosine phosphatase 2 (Shp2) further enhanced m

43 Shp2 (the Src homology-2 domain containing protein tyrosine phosphatase 2), a ubiquitously expresse

44 ze oxidized Src homology 2 domain-containing protein-tyrosine phosphatase 2 (SHP2).

45 eduction of Src homology 2 domain-containing protein-tyrosine phosphatase 2, known to maintain vascul

46 The Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) is an oncogenic ph

47 SH2 containing protein tyrosine phosphatase-2 (SHP2) is an oncogenic ph

48 ors trigger Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) translocation to t

49 two of them, thyrotroph embryonic factor and protein tyrosine phosphatase 4a1, resulted in altered GL

50 ecule inhibitor of the oncogenic phosphatase protein tyrosine phosphatase 4A3 binds to at least one s

51 Protein-tyrosine phosphatase 4A3 (PTP4A3) is highly expr

52 s an E3 ligase for STEP61 (striatal-enriched protein tyrosine phosphatase), a protein tyrosine phosph

53 These three genes encode a non-receptor type protein tyrosine phosphatase, a serine/threonine protein

54 ling in cells, suggesting inhibition of SHP2 protein tyrosine phosphatase activity by this peptide.

55 sine-phosphorylated ligands and inhibits its protein-tyrosine phosphatase activity.

56 mains incompletely understood, receptor type protein tyrosine phosphatase alpha (PTP-alpha encoded by

57 Protein tyrosine phosphatase alpha (PTPalpha) promotes i

58 Receptor-type protein tyrosine phosphatase alpha (RPTPalpha) is an imp

59 Further, we identify a receptor type-protein tyrosine phosphatase alpha-Src family kinase-Rap

60 ions of the focal adhesion kinase (FAK) with protein-tyrosine phosphatase-alpha (PTP-alpha) in IL-1 s

61 STEP is a protein tyrosine phosphatase (also known as PTPN5), with

62 in its activation through the stimulation of protein tyrosine phosphatases, an effect shared by other

63 Bro1 proteins HD-PTP (His domain-containing protein tyrosine phosphatase) and BROX (Bro1 domain and

64 decreased oxidative stress and oxidation of protein tyrosine phosphatases, and ameliorated activatio

65 Protein-tyrosine phosphatases are important reactive oxy

66 e TCR expression and increased expression of protein tyrosine phosphatases as compared with naive T c

67 Mtb protein tyrosine phosphatase B (mPTPB) is a virulence fa

68 Protein-tyrosine phosphatase B (PtpB), a secretory phosp

69 The second PDZ domain of the protein tyrosine phosphatase BL (PDZ2) interacts and bin

70 We investigated whether inhibition of protein tyrosine phosphatases by ROS contributed to H-RA

71 Classical protein-tyrosine phosphatases can exhibit substrate spec

72 The receptor-like protein tyrosine phosphatase CD45 positively regulates c

73 T cells require the protein tyrosine phosphatase CD45 to detect and respond

74 receptor was identified as the cell surface protein tyrosine phosphatase CD45.

75 or type 7 (PTPN7), also called hematopoietic protein tyrosine phosphatase, controls extracellular sig

76 The non-receptor isoform of protein-tyrosine phosphatase (cyt-PTPe) supports adhesio

77 marily with a transsynaptic binding partner, protein tyrosine phosphatase delta (PTPdelta); however,

78 We also demonstrated that T-cell protein-tyrosine phosphatase dephosphorylates pTyr(243)

79 n between the N-SH2 domain and the catalytic protein tyrosine phosphatase domain of SHP-1.

80 zyme, the interactions between its N-SH2 and protein-tyrosine phosphatase domains are weakened such t

81 SHP2 is a nonreceptor protein tyrosine phosphatase encoded by the PTPN11 gene

82 SHP2 protein-tyrosine phosphatase (encoded by Ptpn11) positiv

83 Female mice lacking protein tyrosine phosphatase epsilon (PTP epsilon) are m

84 st that novel biological pathway such as the protein tyrosine phosphatase family is involved in regul

85 ed as PIR1) is a member of the atypical DUSP protein tyrosine phosphatase family.

86 ro substrate preference of 16 members of the protein-tyrosine phosphatase family.

87 rast, elevated expression of Lar, a receptor protein tyrosine phosphatase found to be necessary for a

88 e PSTPIP2 inhibitory function is mediated by protein tyrosine phosphatases from the proline-, glutami

89 zed that the structural features of receptor protein tyrosine phosphatase-gamma (RPTPgamma) that are

90 everal tumor suppressor genes, including the protein tyrosine phosphatase gene PTPROt, which became s

91 ors of Rac and Rho proteins and the receptor protein-tyrosine phosphatase genes PTPRM and PTPRE.

92 tes EGFR dephosphorylation via activation of protein-tyrosine phosphatase H1 (PTPH1).

93 Recently, protein tyrosine phosphatases have emerged as critical r

94 Protein tyrosine phosphatases have received little atten

95 e phosphatases (PTPs) includes hematopoietic protein-tyrosine phosphatase (HePTP), striatal-enriched

96 Here, we show that deletion of Ptpn21, a protein tyrosine phosphatase highly expressed in HSCs, i

97 phatase nonreceptor type 11 Ptpn11 (Shp2), a protein tyrosine phosphatase implicated in multiple cell

98 al-enriched protein tyrosine phosphatase), a protein tyrosine phosphatase implicated in several neuro

99 This is the first time a protein tyrosine phosphatase, implicated in platelet sig

100 e temporal regulation of a specific class of protein tyrosine phosphatases in controlling the rate, a

101 However, the role of protein tyrosine phosphatases in leukocyte recruitment i

102 nce of the ERK phosphatase striatum-enriched protein-tyrosine phosphatase in hemideletion males.

103 details of reactive oxygen species-catalyzed protein-tyrosine phosphatase inactivation have remained

104 scular permeability via vascular endothelial-protein tyrosine phosphatase inhibition limits mycobacte

105 rotein VAPB interacts with the mitochondrial protein tyrosine phosphatase-interacting protein-51 (PTP

106 ine phosphatase 1B (PTP1B), an ER-associated protein tyrosine phosphatase involved in the negative re

107 STEP (STriatal-Enriched protein tyrosine Phosphatase) is a neuron-specific phosp

108 yrosine phosphatase, STEP (STriatal-Enriched protein tyrosine Phosphatase) is an important regulator

109 ase 2), a ubiquitously expressed cytoplasmic protein tyrosine phosphatase, is implicated in regulatin

110 Receptor protein tyrosine phosphatase-kappa (PTPRK) specifically

111 PTPRB is a transmembrane protein tyrosine phosphatase known to regulate blood ves

112 ular endothelial cadherin, the transmembrane protein tyrosine phosphatase LAR, and the RAC1 guanidine

113 s with the Ig domains of LAR family receptor protein tyrosine phosphatases (LAR-RPTPs; LAR, PTPdelta,

114 hosphatase that was identified, the receptor protein tyrosine phosphatase leukocyte-antigen-related (

115 res of two catalytically inactive mutants of protein-tyrosine phosphatase-like myo-inositol phosphata

116 The low molecular weight protein tyrosine phosphatase (LMW-PTP) is a regulator of

117 sustained in vivo binding and retention of a protein tyrosine phosphatase mu (PTPmu)-targeted, molecu

118 Switching of the substrate specificity of protein tyrosine phosphatase N12 by cyclin-dependent kin

119 tors of Lck, C-terminal Src kinase (Csk) and protein tyrosine phosphatase N22 (PTPN22).

120 Protein Tyrosine Phosphatase N23 (PTPN23) resides in chr

121 We demonstrated that protein tyrosine phosphatase non-receptor 22 (PTPN22), v

122 Here, we report that protein tyrosine phosphatase non-receptor 3 (PTPN3) prof

123 Protein tyrosine phosphatase non-receptor type 2 (PTPN2)

124 x (MHC), interleukin 23 receptor (IL23R) and protein tyrosine phosphatase non-receptor type 22 (PTPN2

125 A variant in protein tyrosine phosphatase non-receptor type 22 (PTPN2

126 The human protein tyrosine phosphatase non-receptor type 4 (PTPN4)

127 Protein tyrosine phosphatase non-receptor type 5 (PTPN5,

128 ng variant (Ala455Thr) was identified in the protein tyrosine phosphatase non-receptor type 6 (PTPN6)

129 ncluded in prior panel testing: a pathogenic protein tyrosine phosphatase, non-receptor type 11 (PTPN

130 was mediated by direct targeting of PTPN14 (protein tyrosine phosphatase, non-receptor type 14) whic

131 have established that the gene encoding the protein tyrosine phosphatase nonreceptor 22 (PTPN22) mak

132 s, are associated with an allelic variant of protein tyrosine phosphatase nonreceptor 22 (PTPN22), wh

133 The protein tyrosine phosphatase nonreceptor 22 gene (PTPN22

134 ephosphorylated, which could be prevented by protein tyrosine phosphatase nonreceptor type 1 inhibiti

135 Gain-of-function (GOF) mutations of protein tyrosine phosphatase nonreceptor type 11 Ptpn11

136 The protein tyrosine phosphatase nonreceptor type 12 (PTPN12

137 completely abolish FLNA's interactions with protein tyrosine phosphatase nonreceptor type 12, which

138 mon genetic variant in the gene encoding the protein tyrosine phosphatase nonreceptor type 22 (PTPN22

139 An allelic variant of protein tyrosine phosphatase nonreceptor type 22 (PTPN22

140 Inheritance of a coding variant of the protein tyrosine phosphatase nonreceptor type 22 (PTPN22

141 The hematopoietic-specific protein tyrosine phosphatase nonreceptor type 22 (PTPN22

142 protein encoded by the autoimmune-associated protein tyrosine phosphatase nonreceptor type 22 gene, P

143 Protein tyrosine phosphatase nonreceptor type 7 (PTPN7),

144 PTP1B (protein-tyrosine phosphatase nonreceptor type 1, also ca

145 stitution of tryptophan with arginine in the protein tyrosine phosphatase, nonreceptor type 22 gene (

146 on the outside of the mitochondria released protein tyrosine phosphatase, nonreceptor type 6 (SHP1,

147 , resulting from increased expression of the protein tyrosine phosphatase, nonreceptor type, 22 (PTPN

148 y unclear, due to our inability to visualize protein-tyrosine phosphatase oxidation in cells.

149 te increasing evidence for the importance of protein-tyrosine phosphatase oxidation in signal transdu

150 en dephosphorylated by PTP1B, an ER-resident protein tyrosine phosphatase, prior to axonal transport.

151 ree PRL (phosphatases of regenerating liver) protein tyrosine phosphatases (PRL-1, -2 and -3) have be

152 Recently, the receptor-like protein tyrosine phosphatases, protein tyrosine phosphat

153 We demonstrate that the activity of the protein tyrosine phosphatase PTP-PEST, which controls pa

154 Protein tyrosine phosphatase (PTP) 4A3 is frequently ove

155 This paper presents an approach to measure protein tyrosine phosphatase (PTP) activity in individua

156 scribe a novel method for the measurement of protein tyrosine phosphatase (PTP) activity in single hu

157 Here we report that classical protein tyrosine phosphatase (PTP) domains from multiple

158 SHP2 is a nonreceptor protein tyrosine phosphatase (PTP) encoded by the PTPN11

159 CD45 is a receptor-like member of the protein tyrosine phosphatase (PTP) family.

160 Vascular endothelial (VE) protein tyrosine phosphatase (PTP) is an endothelial-spe

161 of IL-4 signaling, we identified reversible protein tyrosine phosphatase (PTP) oxidation as the prim

162 ction mutations in PTPN11, which encodes the protein tyrosine phosphatase (PTP) SHP2, are implicated

163 The non-receptor protein tyrosine phosphatase (PTP) SHP2, encoded by PTPN

164 an adhesion and signaling unit comprised of protein tyrosine phosphatase (PTP)-PEST and the extracel

165 Protein tyrosine phosphatase (PTP)sigma (PTPRS) was show

166 Protein tyrosine phosphatases (PTP) are exciting and nov

167 y hidden allosteric sites is demonstrated in protein tyrosine phosphatases (PTP) by creation of singl

168 d-independent activation of PTKs and induces protein-tyrosine phosphatase (PTP) inactivation.

169 The nonreceptor protein-tyrosine phosphatase (PTP) SHP2 is encoded by th

170 ing, but it does not affect interaction with protein-tyrosine phosphatase (PTP)-PEST.

171 We identified the protein tyrosine phosphatase PTP1B as a therapeutic cand

172 defines a tumor suppressor function for the protein tyrosine phosphatase PTP1B in myeloid lineage ce

173 Protein tyrosine phosphatase PTP1B is a critical regulat

174 sue, Krishnan and colleagues reveal that the protein tyrosine phosphatase PTP1B is upregulated in pat

175 Recently, the protein tyrosine phosphatase PTP1B was identified as a n

176 The protein-tyrosine phosphatase PTP1B is a negative regulat

177 C1-Ten acts as a protein tyrosine phosphatase (PTPase) at the nephrin-PI3

178 serine/threonine phosphatase, and an active protein tyrosine phosphatase, PTPMEG.

179 diet (HFD), but that coordinate loss of the protein tyrosine phosphatase Ptpn1 (encoding PTP1B) enab

180 The novel protein tyrosine phosphatase PTPN14 was identified by ma

181 In addition, deletion of the protein tyrosine phosphatase PTPN2 in tumour cells incre

182 ry interactions are released upon binding of protein tyrosine phosphatase PTPN21.

183 alysis of the dynamics of association of the protein tyrosine phosphatase PTPN22 and lipid phosphatas

184 The protein tyrosine phosphatase PTPN22(C1858T) allelic poly

185 spho-STAT3 were through up-regulation of the protein-tyrosine phosphatase PTPN6.

186 orylated tyrosine 207 (pTyr207)-CrkL and the protein tyrosine phosphatase PTPRC/CD45; these assays we

187 The protein tyrosine phosphatase PTPRJ/DEP-1 has been implic

188 Protein tyrosine phosphatases (PTPs) are enzymes that re

189 Receptor protein tyrosine phosphatases (PTPs) counterbalance RTK

190 FR) coupled to dephosphorylating activity of protein tyrosine phosphatases (PTPs) ensures robust yet

191 as long been recognized, the significance of protein tyrosine phosphatases (PTPs) in cellular signali

192 aptic transmission was also prevented by the protein tyrosine phosphatases (PTPs) inhibitor sodium or

193 inhibition by orthovanadate or depletion of protein tyrosine phosphatases (PTPs) resulted in the rec

194 It is well known that protein tyrosine phosphatases (PTPs) that become oxidize

195 ignaling involves reversible inactivation of protein tyrosine phosphatases (PTPs) through the oxidati

196 aling pathways are very tightly regulated by protein tyrosine phosphatases (PTPs) to prevent excessiv

197 e to various stimuli is tightly regulated by protein tyrosine phosphatases (PTPs).

198 ities of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs).

199 s," contribute to proper signal transduction.Protein-tyrosine phosphatases (PTPs) are thought to be m

200 Protein-tyrosine phosphatases (PTPs) counteract protein

201 screen to investigate the role of classical protein-tyrosine phosphatases (PTPs) in three-dimensiona

202 The kinase interaction motif (KIM) family of protein-tyrosine phosphatases (PTPs) includes hematopoie

203 been expended to develop inhibitors against protein-tyrosine phosphatases (PTPs), nearly all of it u

204 ting liver (PRLs), the most oncogenic of all protein-tyrosine phosphatases (PTPs), play a critical ro

205 c terminals by signaling through presynaptic protein tyrosine phosphatase receptor delta.

206 Here, we show that hepatic expression of Protein Tyrosine Phosphatase Receptor Gamma (PTPR-gamma)

207 We report here that homodimerization of protein tyrosine phosphatase receptor J (PTPRJ, also kno

208 -/-) inner hair cells were fused by P17, and protein tyrosine phosphatase receptor Q, normally linked

209 thetic reinnervation by binding the neuronal protein tyrosine phosphatase receptor sigma (PTPsigma).

210 that attained chromosome-wise significance, protein tyrosine phosphatase receptor T (PTPRT; P=4.8 x

211 We found a CNV region in protein tyrosine phosphatase receptor type D (PTPRD) wit

212 the top-scoring tumor suppressor candidates, protein tyrosine phosphatase receptor type F (PTPRF).

213 study, we address this issue by focusing on protein tyrosine phosphatase receptor type gamma (PTPRG)

214 e the expression of the tyrosine phosphatase protein tyrosine phosphatase receptor type J (PTPRJ), a

215 PTPRD, which encodes the protein tyrosine phosphatase receptor-delta, is one of t

216 expression in muscle, such as myostatin and protein tyrosine phosphatase receptor-gamma.

217 Here we identify the tumor suppressor Protein tyrosine phosphatase receptor-type kappa (PTPRK)

218 on of the RAS pathway in mice that expressed protein tyrosine phosphatase receptor-zeta (PTPRZ), wher

219 Protein-tyrosine phosphatase receptor type G (RPTPgamma/

220 hed protein-tyrosine phosphatase (STEP), and protein-tyrosine phosphatase receptor type R (PTPRR).

221 Protein tyrosine phosphatases regulate a myriad of essen

222 Mutations of PTPRD, a receptor-type protein tyrosine phosphatase regulating cell growth, wer

223 leukocyte antigen-related (Lar), a receptor protein tyrosine phosphatase (RPTP) and the only known D

224 rs in the brain is regulated by the Receptor Protein Tyrosine Phosphatase RPTP69d.

225 The receptor-linked protein tyrosine phosphatases (RPTPs) are key regulators

226 Receptor protein tyrosine phosphatases (RPTPs) play critical regu

227 The receptor-linked protein tyrosine phosphatases (RPTPs) receive cues from

228 phogenetic apoptosis, requiring the receptor protein tyrosine phosphatases (RPTPs): LAR and RPTPsigma

229 caused by gain-of-function mutations in the protein tyrosine phosphatase SH2 domain-containing PTP (

230 Here, we identified a novel role of the protein tyrosine phosphatase SHP-1 in the regulation of

231 y activates Src homology domain 2 containing protein tyrosine phosphatase (SHP) 1 and suppresses prod

232 rylation of Src homology domain 2-containing protein tyrosine phosphatase (SHP) 2 and Src homology do

233 cluding the Src homology 2 domain-containing protein-tyrosine phosphatases Shp1 and Shp2, knockout an

234 Germline activating mutations of the protein tyrosine phosphatase SHP2 (encoded by PTPN11), a

235 The protein tyrosine phosphatase Shp2 (PTPN11) is crucial fo

236 The protein tyrosine phosphatase SHP2 binds to phosphorylate

237 Here, we have analyzed the function of the protein tyrosine phosphatase Shp2 in mice by deleting it

238 Protein tyrosine phosphatase SHP2 is an oncoprotein asso

239 Protein tyrosine phosphatase SHP2 promotes RAF-to-MAPK s

240 We investigated the contribution of protein tyrosine phosphatase Shp2 to lipopolysaccharide

241 pan-RAS were available, an inhibitor of the protein tyrosine phosphatase SHP2, a critical mediator o

242 The protein tyrosine phosphatase SHP2, encoded by PTPN11, is

243 ons in Ptpn11, which encodes the nonreceptor protein tyrosine phosphatase Shp2, show hippocampal-depe

244 n of Flt3ITD, we show that inhibition of the protein tyrosine phosphatase SHP2, which is essential fo

245 The protein-tyrosine phosphatase SHP2 is an allosteric enzym

246 oplasmic BMP10 interacted with both receptor protein tyrosine phosphatase sigma (PTPRS) and STAT3, wh

247 hat within the human immune system, receptor protein tyrosine phosphatase sigma (PTPRS) is expressed

248 Receptor protein tyrosine phosphatase sigma (PTPsigma) and its su

249 receptor-like protein tyrosine phosphatases, protein tyrosine phosphatase sigma (PTPsigma) and leukoc

250 Protein tyrosine phosphatase sigma (PTPsigma), along wit

251 molecule trans-interacting with presynaptic protein tyrosine phosphatase sigma (PTPsigma).

252 Protein tyrosine phosphatase sigma (PTPsigma, PTPRS), a

253 We further found that protein tyrosine phosphatase sigma (PTPsigma, PTPRS), re

254 Receptor protein tyrosine phosphatase sigma (RPTPsigma) regulates

255 vatives bound to the axon guidance proteins, protein tyrosine phosphatase sigma (RPTPsigma), and Nogo

256 antigen related (LAR) phosphatase subfamily, protein tyrosine phosphatase sigma and LAR, are function

257 function as a positive modulator of the TrkC-protein tyrosine phosphatase sigma complex.

258 Receptor type protein tyrosine phosphatase-sigma (PTPsigma) is primari

259 ypoxia-inducible factor/vascular endothelial protein tyrosine phosphatase signaling and reactive oxyg

260 d the tyrosine phosphatase striatal-enriched protein tyrosine phosphatase (STEP) are known to target

261 Excessive activity of striatal-enriched protein tyrosine phosphatase (STEP) in the brain has bee

262 Striatal-enriched protein tyrosine phosphatase (STEP) is a brain-specific

263 Herein we show that the striatal-enriched protein tyrosine phosphatase (STEP) is recruited by Galp

264 found that the activity of striatal-enriched protein tyrosine phosphatase (STEP) was upregulated by c

265 osine phosphatase (HePTP), striatal-enriched protein-tyrosine phosphatase (STEP), and protein-tyrosin

266 Expression of receptor-like protein tyrosine phosphatase T (PTPRT) mutant proteins i

267 Here, we have identified T cell protein tyrosine phosphatase (TC-PTP), also known as PTP

268 involved in growth factor signaling, T-cell protein tyrosine phosphatase (TC-PTP), and the E3 ubiqui

269 Here, we report the critical role of T-cell protein tyrosine phosphatase (TC-PTP), encoded by Ptpn2,

270 T-cell protein tyrosine phosphatase (TC-PTP), encoded by Ptpn2,

271 Conversely, the T cell protein tyrosine phosphatase (TCPTP) dephosphorylated Tb

272 The T-cell protein tyrosine phosphatase (TCPTP) pathway consists of

273 ntiviral signaling protein (MAVS) and T cell protein tyrosine phosphatase (TCPTP) suggests an avenue

274 ues within ITIMs results in recruitment of a protein tyrosine phosphatase that blocks activation sign

275 domain-containing phosphatase 1 (Shp1) is a protein tyrosine phosphatase that has been identified as

276 Shp2 is a nonreceptor protein tyrosine phosphatase that has been shown to infl

277 encoded by the PTPN11 gene, is a ubiquitous protein tyrosine phosphatase that is a critical regulato

278 selection is followed by the recruitment of protein tyrosine phosphatases that inactivate the RTKs a

279 P1B) is a ubiquitously expressed nonreceptor protein-tyrosine phosphatase that regulates various cell

280 he activity of the receptor and non-receptor protein-tyrosine phosphatases that down-regulate Met pho

281 The induction of protein-tyrosine phosphatases, thioredoxin, SOCS, and Eg

282 cells and inhibit inflammation by recruiting protein tyrosine phosphatases to ITIMs.

283 Protein-tyrosine phosphatase TULA-2 has been shown to re

284 e HPVs bind to the host cellular nonreceptor protein tyrosine phosphatase type 14 (PTPN14) and direct

285 and Tyr(1143), and show that both c-Src and protein tyrosine phosphatase type 1D (PTP-1D) coimmunopr

286 the drosophila ortholog of the non-receptor protein tyrosine phosphatase type II (SHP2) to the Pi3k2

287 Expression of vascular endothelial protein tyrosine phosphatase VE-PTP (also known as PTPRB

288 x with VEC and its phosphatases, EC-specific protein tyrosine phosphatase (VE-PTP) and Src homology p

289 ity and determined that vascular endothelial protein tyrosine phosphatase (VE-PTP) is a HIF2alpha tar

290 ompetitive inhibitor of vascular endothelial-protein tyrosine phosphatase (VE-PTP) that promotes Tie2

291 on including claudin-5, vascular endothelial-protein tyrosine phosphatase (VE-PTP), and von Willebran

292 e, we demonstrated that vascular endothelial-protein tyrosine phosphatase (VE-PTP), which negatively

293 in, known to be involved in stabilization of protein-tyrosine phosphatases, were found to be induced

294 s were shown to co-express striatal-enriched protein tyrosine phosphatase, which may have an importan

295 that dephosphorylate STAT3, such as receptor protein tyrosine phosphatases, which are encoded by the

296 ngaged receptor/ligand complex from receptor protein tyrosine phosphatases with large ectodomains, su

297 SHP2 is a nonreceptor protein tyrosine phosphatase within the mitogen-activate

298 cultures, we demonstrate a role of receptor protein tyrosine phosphatase zeta (RPTPzeta) in PNN stru

299 IL-34, c-FMS, and a second IL-34 receptor, protein-tyrosine phosphatase zeta (PTP-zeta) were upregu

300 Our previous work demonstrated that receptor protein-tyrosine phosphatase zeta (RPTPzeta)/phosphacan