ライフサイエンスコーパス: proteolytically

1 how that the function of LOX-1 is controlled proteolytically.

2 h mature dimeric growth factors are released proteolytically.

3 subset of the CP N-terminal regions becomes proteolytically accessible in the expanded form, althoug

4 in L (Cat L) is a cysteine protease that can proteolytically activate CCAAT displacement protein/cut

5 ains of Coa and vWbp associate with, and non-proteolytically activate prothrombin.

6 Prostasin is unable to proteolytically activate the matriptase zymogen directly

7 AP301 increased current in proteolytically activated (cleaved) but not near-silent

8 Mammalian SREBPs are proteolytically activated and liberated from the membran

9 d) with bovine Pg than with human Pg and non-proteolytically activated bovine but not human Pg.

10 ugh its receptor-binding domain (RBD) and is proteolytically activated by human proteases.

11 muscle cells generated pro-MMP-1, which was proteolytically activated by mast cell tryptase.

12 -activated receptor 1 (PAR1) is irreversibly proteolytically activated by thrombin.

13 uced degradation of the cell surface pool of proteolytically activated ENaC, which enhanced its recyc

14 teins at the single-molecule level: C3b, the proteolytically activated form of C3, and factor H (FH),

15 t here the 2.3 A resolution structure of the proteolytically activated form of Cry5B.

16 tA pro-protein was compared with that of the proteolytically activated protein and with E. coli TatA.

17 nstrating that the activity of many of these proteolytically activated protein fragments can be atten

18 -coupled receptor (GPCR) for thrombin and is proteolytically activated, similar to the prototypical P

19 A is produced as a proprotein, which must be proteolytically activated; generally, cell surface activ

20 PAR1 is proteolytically-activated by bloodstream serine protease

21 ctivated receptor (PAR)-4 is a member of the proteolytically-activated PAR family of G-protein-couple

22 We discovered that MBTPS1/SKI-1/S1P, which proteolytically activates a class of transmembrane trans

23 eptors (NLRs) whose stimulation recruits and proteolytically activates caspase-1 within the inflammas

24 In particular, MMP-8 proteolytically activates IL-8 and, thereby, regulates n

25 The inflammatory mediator thrombin proteolytically activates protease-activated receptor (P

26 Proteolytically active ADAMs are responsible for ectodom

27 Proteolytically active ADAMTS9, but not a catalytically

28 , like the human orthologue HtrA1, BbHtrA is proteolytically active against numerous extracellular pr

29 s promote assembly of inactive hexamers into proteolytically active cages with 12, 18, 24, or 30 subu

30 4 days p.i.) harboring NMI or NMII contained proteolytically active cathepsins and quickly degraded E

31 ot be accurately measured immunologically in proteolytically active CF secretions; mucins are hyperco

32 of Oma1 impair its ability to form a labile proteolytically active complex in response to stress sti

33 erine protease factor VIIa (FVIIa) to form a proteolytically active complex that can trigger coagulat

34 thout inducing apoptosis by functioning in a proteolytically active complex with FLICE-like inhibitor

35 C4b provides a platform for assembly of the proteolytically active convertases that mediate downstre

36 idermis: a one-chain zymogen and a two-chain proteolytically active form, generated by matriptase-dep

37 n and transformation of plasminogen into its proteolytically active form, plasmin, enhances the abili

38 Purified PcADAMp protein was proteolytically active in casein zymography, requiring d

39 ursors, we demonstrated that all of them are proteolytically active in vitro, but that when expressed

40 active intermediate, prethrombin; or (2) the proteolytically active intermediate, meizothrombin (fIIa

41 es cargo degradation by enabling fusion with proteolytically active lysosomes enriched in the soma.

42 Proteolytically active meprinalpha leads to an increase

43 1 is secreted as a mature, glycosylated, and proteolytically active metalloprotease, capable of cleav

44 ADAMDEC1 is a proteolytically active metzincin metalloprotease display

45 Ectopic expression of proteolytically active MMP3 in mouse mammary epithelia t

46 Proteolytically active MVs induced by tobacco smoke may

47 esults in disassembly, ensuring that DegP is proteolytically active only when sufficient quantities o

48 in plasma as a zymogen and when converted to proteolytically active plasmin dissolves preformed fibri

49 MBP in shiverer mice and mutagenesis of the proteolytically active site in MBP or of the MBP cleavag

50 i), LMP2 (beta1i), and LMP7 (beta5i) are the proteolytically active subunits of the immunoproteasome

51 trate binding converts inactive trimers into proteolytically active trimers, and simultaneously leads

52 ritance is important for rapid generation of proteolytically active vacuolar compartments in daughter

53 e of directing translation and production of proteolytically active viral proteinase 2A in human card

54 ay but that NETs produced by all stimuli are proteolytically active, kill bacteria and composed mainl

55 ell invasion when CTSB was overexpressed and proteolytically active.

56 The oligomers were unimolecular and proteolytically active.

57 may provide a generic approach for designing proteolytically-actuated peptides for tumor-penetrative

58 These proteins are presumed to be trimmed proteolytically and undergo posttranslational modificati

59 mitochondrion and found that it is processed proteolytically at a WGSS cleavage site into a heterodim

60 er with a cognate inhibitor for execution of proteolytically biologic function; however, TMPRSS2's co

61 -A produced in oligodendrocytes is processed proteolytically by BACE1, is released via exosomes, and

62 ngth Reelin and its N-terminal fragment N-R6 proteolytically cleave L1 to generate an L1 fragment wit

63 intracellular and extracellular enzymes that proteolytically cleave proBDNF furin and tissue plasmino

64 ies suggest a pathway wherein YjbH and ClpXP proteolytically cleave Spx, a repressor of cspA transcri

65 Matrix metalloproteinases (MMPs) can proteolytically cleave VEGF, which might inhibit progeni

66 The ectodomain is proteolytically cleaved (S1) in response to ligand-induc

67 VEGFC and VEGFD are proteolytically cleaved after cell secretion in vitro, a

68 In this study, we demonstrated that GAB1 was proteolytically cleaved after CVB3 infection at G175 and

69 roteins (ZP1, ZP2, and ZP3), of which ZP2 is proteolytically cleaved after gamete fusion to prevent p

70 of pIgR, termed secretory component (SC), is proteolytically cleaved and released either unbound (fre

71 Under low oxygen, Sre1 is proteolytically cleaved and the N-terminal transcription

72 PC1 must also be proteolytically cleaved at a GPS site for this to occur.

73 expressed, transported to cell surfaces, and proteolytically cleaved at levels comparable to that of

74 In some cases, the S protein is proteolytically cleaved at the S1-S2 boundary.

75 Since PKCdelta can be proteolytically cleaved by caspase-3 during apoptosis, t

76 The ectodomain of TLR9 must be proteolytically cleaved by endosomal proteases to produc

77 Many guidance receptors are proteolytically cleaved by membrane-associated metallopr

78 is synthesized as a large precursor that is proteolytically cleaved by OGT, which may regulate its b

79 f extracellular matrix remodeling, whereby a proteolytically cleaved CDCP1 regulates in vivo locomoti

80 or Escherichia coli DH5alpha showed that Cpa proteolytically cleaved complement components C3, C3a, a

81 Proteolytically cleaved CP subunits dissociate from the

82 ted skin grafts in mice via the release of a proteolytically cleaved fluorescence reporter that filte

83 their interaction with factor I and C3b, the proteolytically cleaved form of C3.

84 ncreased levels of the catalytically active, proteolytically cleaved form of CatD, corresponding with

85 ecans (SDCs), the latter occurring mainly in proteolytically cleaved form, as membrane-spanning C-ter

86 ow that TLR9(471-1032), corresponding to the proteolytically cleaved form, does not function on its o

87 Both proteins bound to three of the four proteolytically cleaved fragments of MSP1 (p42, p38, and

88 f the constituent components are released as proteolytically cleaved fragments.

89 e amyloid precursor protein (APP), PrP(C) is proteolytically cleaved from the cell surface by a disin

90 normal tissues and cell lines, the kinase is proteolytically cleaved from the channel domain in a cel

91 In humans, proteolytically cleaved HCII forms were detected during

92 inogen (HK) is an endogenous protein that is proteolytically cleaved in plasma and on endothelial cel

93 zymography, and Western blot, which in turn proteolytically cleaved in situ the Abeta peptides.

94 oposed that a significant fraction of APP is proteolytically cleaved in the neuronal soma into N- and

95 For APP to be proteolytically cleaved into Abeta, it must be internali

96 In vivo, SltB is proteolytically cleaved into its two principal domains.

97 In vivo, Slit is proteolytically cleaved into N- and C-terminal fragments

98 ANGPTL4 protein is then proteolytically cleaved into several forms by proprotein

99 atis) and C. pneumoniae, the PmpD protein is proteolytically cleaved on the cell surface.

100 ne adrenal medulla 8-22 peptide (BAM8-22), a proteolytically cleaved product of proenkephalin A, is a

101 ely, overexpression of plasmids encoding the proteolytically cleaved SIRPalpha fragments in cells res

102 tant indicates the presence of an 18-residue proteolytically cleaved species.

103 as brought iRGD to the tumor, the peptide is proteolytically cleaved to expose the cryptic CendR moti

104 o the cytoplasm, where it accumulates and is proteolytically cleaved to form C-terminal fragments.

105 lagen XV/XVIII, a matrix protein that can be proteolytically cleaved to release Endostatin, an antian

106 Specifically, RARRES1, which is proteolytically cleaved to release the extracellular dom

107 Following secretion, ACBP is proteolytically cleaved to the active neuropeptides by p

108 e completely blocked, p120 Nrf1 can still be proteolytically cleaved to the p110 form, which is trans

109 des the glycoprotein precursor (GPC) that is proteolytically cleaved to yield two viral structural gl

110 usly been achieved by generating soluble and proteolytically cleaved trimers of gp140 Env that are st

111 Without the SOS and IP changes, proteolytically cleaved trimers tend to disintegrate int

112 l regulatory element-binding protein Sre1 is proteolytically cleaved under low oxygen, and its N-term

113 Hepatic MMP-9 proteolytically cleaved VEGF after partial hepatectomy.

114 INF2 is proteolytically cleaved, a process mediated by cathepsin

115 r is synthetized as a preprohormone which is proteolytically cleaved, and acylated by a membrane-boun

116 f these pathways, complement component C4 is proteolytically cleaved, and the major product C4b is de

117 hybrid GPC complexes are properly assembled, proteolytically cleaved, and transported to the cell sur

118 ulating partner mediating cross-talk between proteolytically cleaved, membrane-retained CDCP1 and mem

119 ork, we show that in quiescent cells DBC1 is proteolytically cleaved, producing a protein (DN-DBC1) t

120 Full-length CDCP1 (flCDCP1) can be proteolytically cleaved, resulting in a cleaved membrane

121 subunit of neuronal L-type VGCCs, Cav1.2, is proteolytically cleaved, resulting in Cav1.2 fragment ch

122 s efficiently expressed on cell surfaces and proteolytically cleaved.

123 lular, ligand-binding portion of the pIgR is proteolytically cleaved.

124 T4.13, the C-terminal extension of SPI-1 was proteolytically cleaved.

125 Whereas FI-FH proteolytically cleaves C3b into iC3b, PAM-bound hPm cat

126 Plasma kallikrein (pKal) proteolytically cleaves high molecular weight kininogen

127 ADAM10 is a "molecular scissor" that proteolytically cleaves the extracellular region from >1

128 ke protease, nsp5, is an IFN antagonist that proteolytically cleaves the nuclear transcription factor

129 is implicated in leukocyte transmigration by proteolytically cleaving its endothelial substrates.

130 oprotein convertase subtilisin/kexin enzymes proteolytically convert immature proproteins into bioact

131 The zymogen prothrombin is proteolytically converted by factor Xa to the active pro

132 ic proteins to autolysosomes where they were proteolytically converted into products capable of killi

133 the endocytic compartment, where virions are proteolytically converted to infectious subvirion partic

134 acillus subtilis, induces plasma clotting by proteolytically converting ProT into active sigmaPre2, a

135 Our data show that proteolytically damaged areas in porcine metacarpophalan

136 damaged fibers are repaired longer, whereas proteolytically damaged fibers are repaired shorter, rel

137 oly(ethylene-glycol) (PEG) hydrogels, with a proteolytically degradable core and a non-degradable she

138 ascular cells encapsulated in cell-adhesive, proteolytically-degradable poly(ethylene) glycol-based h

139 MMP-9 was confirmed in vitro and in vivo to proteolytically degrade CD36.

140 ase activity, active serine proteases, which proteolytically degrade NET-associated proteins and prom

141 During stress, DinJ is proteolytically degraded and free YafQ halts translation

142 After entry into the endosome, sigma3 is proteolytically degraded and mu1 is cleaved and exposed

143 contain stoichiometric flavin, type 1 CRY is proteolytically degraded by a light-initiated reaction i

144 nt evidence that like lambda CII, 186 CII is proteolytically degraded in vivo, but unlike lambda CII,

145 hexylamine, lysine-containing peptides, or a proteolytically degraded protein, it bound to MDA-modifi

146 ence of its partner protein, SleB or YpeB is proteolytically degraded soon after expression during sp

147 dividual subunits of fatty acid synthase are proteolytically degraded when the respective partner is

148 posed that the protein component of a DPC is proteolytically degraded, giving rise to smaller DNA-pep

149 component of DNA-protein cross-links can be proteolytically degraded, resulting in smaller DNA-pepti

150 with natriuretic peptide receptors and to be proteolytically degraded.

151 Cathepsin B (CatB) proteolytically degrades Abeta into non-aggregating frag

152 ClpP proteolytically degrades folded proteins only when assoc

153 omplex consists of a core particle (CP) that proteolytically degrades polyubiquitylated proteins, and

154 ne proteinase, is activated during aging and proteolytically degrades tau, abolishes its microtubule

155 ), a specialized group of enzymes capable of proteolytically degrading extracellular matrix proteins,

156 part, on the basis of work conducted with a proteolytically derived form of phosphorylase that lacke

157 trafficking by secreting a peptide (PEPITEM) proteolytically derived from 14.3.3 zeta delta (14.3.3.z

158 nslationally modified signaling peptides are proteolytically derived from larger precursor proteins a

159 hydrogen-deuterium exchange patterns within proteolytically derived peptides allows spatial resoluti

160 employed for isolating phosphopeptides from proteolytically digested plasma membranes of Arabidopsis

161 he peptide harboring the FLNH(2) can then be proteolytically digested, purified by HPLC and then iden

162 quantitation of CFTR peptides produced from proteolytically digesting the plasma membrane subproteom

163 Thus, a proteolytically diverse portfolio exists for MT1-MMP wit

164 During a proteolytically-driven maturation process, the orthoretr

165 zothiazole (CBT) condensation for labeling a proteolytically exposed N-terminal cysteine.

166 s could restore immune effector functions to proteolytically generated F(ab')2 fragments.

167 Using proteolytically generated Fn fragments and purified reco

168 -related GTPases that mediate fusion, become proteolytically inactivated.

169 s down the complex that produces thrombin by proteolytically inactivating factor Va.

170 A proteolytically inactive form of APC with reduced antico

171 We report that iRhom2 (RHBDF2), a proteolytically inactive member of the rhomboid family,

172 r ADAMTS20 acting in trans, but not by their proteolytically inactive mutants.

173 , in vitro transcribed mRNA, which encodes a proteolytically inactive Papp-a mutant, recues the papp-

174 Proteolytically inactive prostasin, unlike the wild-type

175 s linked to mutations in RHBDF2 encoding the proteolytically inactive rhomboid protein, iRhom2.

176 overexpression of wild-type YME1L but not a proteolytically inactive YME1L variant.

177 otein quality control but are presumed to be proteolytically inactive.

178 typic ubiquitin chains on p27(Kip1) that are proteolytically incompetent.

179 In contrast, this domain remains proteolytically labile in cells producing only one of th

180 Using trypsin proteolysis, we identified the proteolytically labile sites in the C-terminal domain (a

181 MSP1 is extensively proteolytically modified, first just before egress and t

182 Calpain enzymes proteolytically modulate cellular function and have been

183 hydrolytically, whereas natural ECM degrades proteolytically, often through matrix metalloproteinases

184 ates: in its unmodified quiescent form, in a proteolytically "on" state induced by ethylenediaminetet

185 Diminished binding of soluble hTSP-1 to proteolytically pretreated staphylococci suggested a pro

186 hat they can do so after the glycoprotein is proteolytically primed and bound to its intracellular re

187 s reach an endosomal compartment where GP is proteolytically primed by cathepsins.

188 GP(1) and GP(2) that remain after GP(1,2) is proteolytically primed by endosomal cathepsins for fusio

189 y, and neutralize viral entry by targeting a proteolytically primed, fusion-competent GP intermediate

190 t with a model that the amon protein acts to proteolytically process a diverse suite of peptide hormo

191 e members of the ABC transporter family that proteolytically process and export peptides and proteins

192 ppropriate spatiotemporal pattern in vivo to proteolytically process Cad6B.

193 ive temperature, MHV-Brtsc31 was not able to proteolytically process either p150, the precursor polyp

194 l analysis that proprotein convertases (PCs) proteolytically process human Pxdn at Arg-1336, a locati

195 However, calpains can proteolytically process PKCs, and the potential in vivo

196 BclA contains a proteolytically processed 38-residue amino-terminal doma

197 In response to CpG DNA stimulation, the proteolytically processed 80-kDa fragment is tyrosine ph

198 ocess is known to decrease the expression of proteolytically processed active channels on the cell su

199 inal mitochondrial targeting peptide that is proteolytically processed after import into the mitochon

200 bilized from the ER to the Golgi where it is proteolytically processed and released to enter the nucl

201 Here, we show that hTLR7 is proteolytically processed and that the C-terminal fragme

202 Upon heat stress, AtBAG7 is sumoylated, proteolytically processed and translocated from the ER t

203 In contrast, proteolytically processed ARSG fragments of 34-, 18-, an

204 is study indicates that C. abortus Pmp18D is proteolytically processed at the cell surface similar to

205 nd SprE may modify the cell wall affinity of proteolytically processed AtlA resulting in either a pro

206 ns, adhesins, and proteases, are extensively proteolytically processed both pre- and postexocytosis.

207 We show that although the S1/S2 site is proteolytically processed by furin during protein biosyn

208 polyposis coli (APC), and GSK3beta were also proteolytically processed by P. gingivalis gingipains.

209 Upon migration to the Golgi, bZIP28 is proteolytically processed by proteases S1P and S2P.

210 Fpr1 is secreted and proteolytically processed by the fungus.

211 ane-anchored long forms of OPA1 (l-OPA1) are proteolytically processed by the OMA1 or YME1L proteases

212 nalyses, we report that the LOX precursor is proteolytically processed by the procollagen N-proteinas

213 h the nucleocapsids of some PEDV strains are proteolytically processed by the virally encoded main pr

214 ncode large replicase polyproteins which are proteolytically processed by viral proteases to generate

215 ssion of a lantibiotic-type bacteriocin, but proteolytically processed derivatives of the phenol-solu

216 ay requires a signaling complex in which the proteolytically processed distal C-terminal domain acts

217 binds to cell-surface receptors and is then proteolytically processed forming a LF-binding competent

218 y, our study identifies histone H3.3 and its proteolytically processed forms as key regulators of cel

219 mineralization of bone and dentin, exists as proteolytically processed fragments in the mineralized t

220 e functional region for CLV3, and that it is proteolytically processed from the CLV3 precursor protei

221 The octapeptide angiotensin II (AII) is proteolytically processed from the decapeptide AI by ang

222 l nsp1 in these processes, using nsp1beta, a proteolytically processed functional product of nsp1 as

223 and lymphangiogenic glycoprotein that can be proteolytically processed generating various forms diffe

224 ARSG is expressed and proteolytically processed in a tissue-specific manner.

225 The TLR9-GFP transgene is functional and is proteolytically processed in resting bone marrow-derived

226 asmic reticulum (ER), and is transported and proteolytically processed in the Golgi apparatus under c

227 he distal portion of the C terminus (DCT) is proteolytically processed in vivo and serves as a noncov

228 Progranulin is proteolytically processed into granulins, but the role o

229 (LC-MS/MS) analyses suggested that ChiA was proteolytically processed into two GH18 domain-containin

230 by INFLORESCENCE DEFICIENT IN ABSICSSION, a proteolytically processed peptide ligand, activating the

231 5 from apple and RPS2, both of which require proteolytically processed RIN4 for activation.

232 ic construct, it was discovered that MT1-MMP proteolytically processed the pro-fibrotic molecule, lat

233 Early during germination, YpeB is proteolytically processed to a stable fragment.

234 ute its function, the intact-Ac45 protein is proteolytically processed to cleaved-Ac45 thereby releas

235 through endosome to the lysosome where it is proteolytically processed to enzymatically active-CD.

236 Herein we report that human TLR3 is proteolytically processed to form two fragments in endos

237 nt CLEs are posttranslationally modified and proteolytically processed to function as bioactive ligan

238 RPTP-kappa is proteolytically processed to isoforms that have opposing

239 expressed as a transmembrane protein that is proteolytically processed to release a soluble form.

240 a is synthesized as a precursor molecule and proteolytically processed to the mature form by members

241 sp1/11(-/-) BMDC indicated that caspase-8 is proteolytically processed within detergent-insoluble ASC

242 ith pulmonary diseases, and full-length (not proteolytically processed) IL-33 is the predominant form

243 protein phosphatase PGAM5, which we show is proteolytically processed, accumulates in cytosol during

244 At red blood cell invasion MSP1 is proteolytically processed, and the 19-kDa C-terminal fra

245 The MGA0674-encoded lipoprotein is a proteolytically processed, immunogenic, TX-114 detergent

246 s critical for the latter, which consists of proteolytically processed, infectious virus progenies wi

247 The proteolytically processed, mature form of pVI, protein V

248 s the ER and moves to the Golgi, where it is proteolytically processed, releasing its transcriptional

249 s showed that PyrR and PyrD are taken up and proteolytically processed.

250 ts C-terminus, and we demonstrate that it is proteolytically processed.

251 Additionally, we observed that Dsg2 is proteolytically processed; resulting in a 95-kDa ectodom

252 d into the parasitophorous vacuole, where it proteolytically processes a subset of parasite proteins

253 e found that the 55-kDa Tpr inactive zymogen proteolytically processes itself into active forms of 48

254 dogenous angiogenesis inhibitors but require proteolytically processing by furin to compete with VEGF

255 ll as caspase-8, regulated LUBAC activity by proteolytically processing HOIP at Asp-348 and Asp-387 d

256 Autoactivation of cationic trypsinogen is proteolytically regulated by chymotrypsin C (CTRC), whic

257 In Escherichia coli, such antitoxins are proteolytically regulated by the ATP-dependent proteases

258 VWF platelet-tethering function is proteolytically regulated by the metalloprotease ADAMTS1

259 ADAMTS13 proteolytically regulates the platelet-tethering functio

260 l fragment, called the PF-AB domain, becomes proteolytically released as well, but much less is known

261 Proteolytically released extracellular matrix (ECM) frag

262 Mechanistically, these studies reveal that a proteolytically released fragment of this collagen, term

263 extracellular domain of the PDGFRbeta can be proteolytically released from cell membranes and, if so,

264 Collagen XVII is proteolytically released from the membrane, and the path

265 The extent to which phage is proteolytically released from the resin was found to be

266 Proteolytically released GAGs are involved in the genera

267 4 (ErbB4) is a kinase that can signal via a proteolytically released intracellular domain (ICD) in a

268 Importantly, proteolytically released sIL-23R has IL-23 binding activ

269 Gag is then processed proteolytically, releasing the capsid protein (CA) to as

270 egligible binding to full-length GP, bound a proteolytically remodeled GP with picomolar affinity, su

271 Ripe fruit extracts proteolytically removed the NTT of 27-kD AcCYS1 in vitro

272 l extensions of the ClpP/R subunits were not proteolytically removed upon assembly, suggesting a regu

273 ic resistance from a weakly proinflammatory, proteolytically resistant amniote ancestor.

274 ion of a SIRPalpha mutant plasmid encoding a proteolytically resistant form in HeLa cells inhibited a

275 in the large-scale synthesis of functional, proteolytically resistant peptide-polymer conjugates for

276 Being proteolytically resistant, D-peptides lack interactions

277 Cytidylyltransferase (CCTalpha) is a proteolytically sensitive lipogenic enzyme containing an

278 forms a beta-barrel when expressed alone or proteolytically separated from the NTD, indicating that

279 e heparan sulfate proteoglycan syndecan-1 is proteolytically shed from the surface of multiple myelom

280 ting enzyme (TACE, herein denoted as Adam17) proteolytically sheds several cell-surface inflammatory

281 uch peptides, which are conformationally and proteolytically stabilized with all-hydrocarbon staples,

282 Here we describe a novel FPR2 agonist, the proteolytically stable alpha-peptide/beta-peptoid hybrid

283 he study highlights the discovery of a novel proteolytically stable cyclic peptide that can be used f

284 dified to provide antibacterially active and proteolytically stable derivatives.

285 This type of proteolytically stable FPR2-specific peptidomimetics may

286 In our continued effort to design a proteolytically stable ligand with specific receptor bin

287 -dimensional structure of a native HCT and a proteolytically stable lysine mutant enabled the identif

288 Proteolytically stable peptide architectures are require

289 alpha- and beta(3)-residues have emerged as proteolytically stable structural mimics of alpha-helice

290 laying a central role in the assembly of the proteolytically stable trimeric complex and its correct

291 n1) isomerase resulted in potent, selective, proteolytically stable, and biologically active inhibito

292 sequence amylin peptides (12-14 aa) that are proteolytically stable, brain penetrant when administere

293 Yos9, consisting of residues 22-421, that is proteolytically stable, highly structured, and able to f

294 This effector proteolytically targeted Rab32, which controls traffic t

295 itreous IGFBP-3 revealed that the protein is proteolytically truncated at the C terminus.

296 ming motif and a cryptic CendR motif that is proteolytically unmasked in tumor tissue.

297 We report that SlrR is proteolytically unstable and present evidence that self-

298 region attached to a DNA binding domain, are proteolytically unstable in yeast, and it has been sugge

299 diseases, including hypertension in which a proteolytically unstable RGS2 mutant has been reported.

300 ssical activators work most efficiently when proteolytically unstable.