ライフサイエンスコーパス: protic

1 The isomerization is promoted by protic acid and active palladium catalyst.

2 The bifunctional chiral protic acid catalyst enables these reactions to proceed

3 ed to tryptamines Xa and Xb under controlled protic acid conditions.

4 When those materials are treated with protic acid in anhydrous solvent, the cinnamyl unit migr

5 increase in acidity of an exceedingly strong protic acid is greater for biscoordinating TiCl4 and SnC

6 ate experimentally observed when an external protic acid is used is attributed to the strong decrease

7 oxyseptanoside 10 as the only product during protic acid mediated elimination reactions.

8 e production of H(2)O(2) upon treatment with protic acid, and independent preparation from reaction o

9 In the presence of protic acid, bridged structures such as 6 are formed rea

10 Under protic acid-mediated dehydrative aromatization condition

11 yama macrolactonization as well as Lewis and protic acid-promoted deprotections carefully designed to

12 Compared to earlier work on the protic acid-promoted intramolecular Schmidt reaction of

13 tion of aromatic amines that are promoted by protic acid.

14 followed by a catalytic amount of an achiral protic acid.

15 ith a peroxyacid in the presence of a strong protic acid.

16 itrogen atom in the presence of 2 equiv of a protic acid.

17 ides cleave to form quinones when exposed to protic acid.

18 The high protic acidity promised by large absolute values of the

19 up from glycals is accomplished by Lewis and protic acids as reagents or catalysts, where the use of

20 of composition {CdSe[n-octylamine]0.53} and protic acids HX (X = Cl, Br, NO3, acetate (OAc), and ben

21 (2), it was discovered that (i) HF and other protic acids inhibit each of the 12 fluorination steps (

22 ngement to methyl isopropyl ketone in strong protic acids involving a reactive protosolvated superele

23 le) connecting the catalytic power Lewis and protic acids.

24 efficient substitute for nonoxidizing strong protic acids/superacids.

25 Here we show that the introduction of the protic additive phenol to ethers can promote a solution-

26 y selectivity and conversion dependence on a protic additive.

27 Benzoic acid and other protic additives (H2O, ArOH) catalyze the oxygenation re

28 While various protic additives could be used to promote the transforma

29 kinetics using NaBH4 accompanied by various protic additives, have been discussed.

30 ent in rate for the activation of H(2) using protic additives, which operate as "proton shuttles".

31 haracter of both nonsolvents, where only the protic alcohols can provide the protons needed to desorb

32 ethods for nitrene-mediated amination of the protic alpha-C-H bonds in carboxylic acid esters, howeve

33 unctionality has been hydrogenated to give a protic amine side group.

34 -tetramethylethylenediamine, Et2O, pyridine, protic amines, alcohols, and highly dipolar aprotic solv

35 While protic ancillary groups are important in the performance

36 pendent screw-sense preference: (P)-helix in protic and (M)-helix in aprotic solvents.

37 suitability of the hydrogen-bonding model in protic and aprotic conditions as well as under basic and

38 these traces by adding small amounts of both protic and aprotic cosolvents.

39 (PEG) chains of moderate sizes dissolved in protic and aprotic liquid electrolytes and find that the

40 MB as the substrate are investigated in both protic and aprotic organic media, showing different colo

41 e models that recognize pyrimidine dimers in protic and aprotic organic solvents as well as in water

42 ixtures (alkaline, acidic, heterogeneous) in protic and aprotic organic solvents.

43 otonated Schiff base of all-trans retinal in protic and aprotic solvents was studied by multipulse ul

44 rimental rates and differentiate between the protic and aprotic solvents.

45 measurements on [Ru(bpy)(2)dppz](2+) in both protic and aprotic solvents.

46 H-bonds in ILs (both protic and aprotic) are bifurcated and chelating, and un

47 e using the shift in the Tafel slope between protic and deuteric electrolytes, or the Tafel slope iso

48 een investigated using QM/MM calculations in protic and dipolar aprotic solvents.

49 Both the polar-protic and dipolar-aprotic solvents resulted in signific

50 In particular, substrates featuring protic and electrophilic functional groups can be used s

51 Similar chemistry can also be achieved for protic and hydridic E-H bonds (N-H/O-H, Si-H/B-H, respec

52 Furthermore, by exploiting the separate protic and hydridic nature of the reagents, it is possib

53 with Reichardt's dyes are very different for protic and nonprotic solvents, even if the relative perm

54 reactivity of this "hydride", however, shows protic and not hydridic behavior.

55 red liquid as well as its nature as a polar, protic, and amphoteric reagent.

56 cluded compounds containing anionic, neutral protic, and cationic peripheral substituents and various

57 and apolar regions on one hand and dipolar, protic, and positively charged on the other.

58 In contrast, appropriate protic anion, e.g., HSO(4)(-) in our case, and weakly hy

59 e growing oligonucleotide intermediates in a protic antisolvent (2-propanol), remained near quantitat

60 ups, and it showed high performance in polar protic/aprotic media, including aqueous buffer systems.

61 Using the doubly protic bis-pyrazole-pyridine ligand (N(NN(H))(2)), we ha

62 macopieal dissolution system with a standard protic buffer.

63 en elimination involving direct elimination, protic catalysts, or binuclear mechanisms and shows that

64 double dagger)(OH) approximately K(NPP) for "protic" catalysts (Co(NH(3))(6)(3+), Co(en)(3)(3+), guan

65 In conjunction with the catalyst, protic chain transfer agents (CTAs) initiate polymerizat

66 robimetallic systems to stabilize developing protic character of the transferring hydrogen in the rat

67 otochemically from SmI(3) in the presence of protic, chiral, and/or Lewis basic additives.

68 The protic-, chloro-, and anti iodo-imidazoliophane receptor

69 gh propargylic hydride migration followed by protic cleavage of the resultant vinylruthenium intermed

70 Impurities include residual protons and protic compounds that can react with oxygen species, suc

71 d, this reaction was strongly accelerated by protic conditions and even by trace amounts of water.

72 he ketone/sulfine ratio can be reversed when protic conditions and high thioketone concentrations are

73 to aryl aldehydes under polar, nonpolar, and protic conditions using both rate data and two isotope e

74 Under protic conditions, two different intermediates are forme

75 ox products were not observed despite of the protic conditions.

76 ilms or catalyst supports under reducing and protic conditions.

77 f an aprotic cosolvent and the addition of a protic cosolvent can slow the reaction due to their hydr

78 ample preparation methods, the addition of a protic cosolvent to the sample solutions was shown to br

79 are therefore required to successfully apply protic CTAs in reversible-deactivation ring-opening copo

80 er lower polymerization rates when used with protic CTAs.

81 l-3-methylimidazolium, X = BF(4), PF(6)) and protic (DEAS = diethanolamine hydrogen sulphate; DEAP =

82 and nonpolar organosilanes as well as polar-protic, dipolar-aprotic, and nonpolar solvents were inve

83 ng the ET driving force and manipulating the protic environment of Y191.

84 duces reactive carbonyl anions in a buffered protic environment that readily undergo conjugate additi

85 eceptors are shown to endocomplex, even in a protic environment, a large variety of primary ammonium

86 In a protic environment, calix[6]tube 4 binds DOPC much more

87 monium sulfate salts was also evidenced in a protic environment.

88 se sites that make the cluster reactive in a protic environment.

89 biased equilibrium favors this conformer in protic environments, while a lipophilic conformer with c

90 he 6DMN fluorescence is red-shifted in polar protic environments, with the maximum emission intensity

91 mplicated by hydrogen bonding (H-bonding) in protic environments.

92 iving/controlled anionic ROP of GL in strong protic fluoroalcohols (FAs), which are conventionally co

93 and presents the opposite scenario in which protic-free conditions are required to prevent cyclic po

94 ided that the acetylene derivative carries a protic functional group.

95 a chemoselective fashion in the presence of protic functional groups and lower halides.

96 Furthermore, many protic functional groups are incompatible with basic flu

97 ydrophobicity through the addition of polar, protic functional groups in the development of a reliabl

98 In molecular catalysts, protic functional groups in the secondary coordination s

99 r the functionalization of NHC surfaces with protic functional groups, such as alcohols and amines, p

100 g heterocycles, N-protected amino acids, and protic functionality can be coupled in 23-96% yield with

101 ntains excellent activity in the presence of protic functionality, exhibiting resilience against thes

102 particle solutions, and its ability to yield protic functionality, greatly expands the potential of N

103 The base-free conditions have exceptional protic group tolerance on both partners, permitting the

104 common dimethacrylates (DMAs) containing no protic groups into unsaturated polyesters.

105 ce of unprotected alcohols and various other protic groups.

106 with different nonpolar (toluene) and polar protic (HFIP) solvents.

107 tem capable of the cooperative activation of protic, hydridic and apolar HX bonds across a Group 13 m

108 difference in the 1H NMR chemical shift of a protic hydrogen in DMSO and CDCl3 solvents is directly r

109 tion-metal or main-group hydride (M-H) and a protic hydrogen moiety (H-X)-is arguably the most intrig

110 For 54 compounds, the observed shifts for 72 protic hydrogens could be correlated to the Abraham solu

111 the determination of A values for individual protic hydrogens in multifunctional solutes.

112 ated dienes and enynes, owning to its facile protic hydropalladation of electron-rich (or neutral) un

113 evidence showing that anion-anion dimers of protic hydroxyanions can form readily, and describe cond

114 Careful analysis of the role of adventitious protic impurities revealed the participation of competin

115 resh look on the Grotthuss-type mechanism in protic ionic glasses as well as provide new ideas for th

116 haviour of sucrose in aqueous solutions of a protic ionic liquid (3-hydroxypropylammonium acetate) ha

117 idodecyldimethylammonium bromide, DDAB) in a protic ionic liquid (ethylammonium nitrate, EAN).

118 Further, the effect of protic ionic liquid on the taste behaviour of sucrose ha

119 Here we study systems in which protic ionic liquid second components dissolve ideally i

120 he strength of the solvophobic effect in the protic ionic liquid.

121 Protic ionic liquids (PILs) are currently being shown to

122 We demonstrate protic ionic liquids (PILs) as effective p-dopant in bot

123 ochemical behavior of platinum electrodes in protic ionic liquids (PILs) by means of in situ Fourier-

124 ormed under electrochemical conditions using protic ionic liquids as solvent for lignin.

125 nd a great similarity of alkylammonium-based protic ionic liquids to liquid water.

126 Such "protic ionic liquids" exhibit a wide range of thermal st

127 hylimidazolium hexafluorophosphate), and two protic ionic liquids, (bis(2-hydroxyethyl)ammonium aceta

128 d-based ionic liquids, such as acetate-based protic ionic liquids, where the widely used Karl Fischer

129 lysis of BPA-PC and PET in the presence of a protic ionic salt TBD:MSA catalyst enables the selective

130 eme systems were made in the presence of the protic Lewis acid, 2,6-lutidinium triflate (LutH(+)), wi

131 uperior catalytic performance from a pool of protic/Lewis acid catalysts, signifying its indispensabl

132 electrons in the near-interfacial region of protic liquids.

133 ivity of alpha,n-didehydrotoluenes (DHTs) in protic media (organic/aqueous mixtures) was explored by

134 rolytic photoactivation of the Ar-Cl bond in protic media and the generation of phenyl cations.

135 apture small and potentially toxic anions in protic media has sparked a renewed interest in the synth

136 solvents and of hydrophobic interactions in protic media in agreement with the experimental spectros

137 In addition, running the reaction in protic media leads to the reduced product resulting from

138 The mechanism of the oxidation in protic media was either one- or two-electron, depending

139 ar and nonpolar aprotic solvents and also in protic media with the aim of controlling nitrogen neighb

140 as high as 10(8) s(-1), even in unfavorable protic media, are described.

141 In these protic media, MeOH or H(2)O solvent molecules displace t

142 rious ortho-methylamino arylboronic acids in protic media.

143 ible for the observed rate enhancements over protic media.

144 ity to reversibly bind 1,2- and 1,3-diols in protic media.

145 by oxoiron(IV) porphyrin cation radicals in protic media.

146 orth-type rearrangement occurring in neutral protic medium or under acid conditions.

147 conversion of 1-QM to an inactive indene in protic medium.

148 f an azide anion to tetrafluoroethylene in a protic medium.

149 nsive study investigated the effect of polar protic (methanol and water) and polar aprotic (acetonitr

150 stream" configuration must be selected when protic mobile phases are used in both dimensions.

151 n bonds in the complexation of fluoride with protic molecules.

152 short HH distance of 1.489(10) A between the protic N-H(delta+) and hydridic Fe-H(delta-) part.

153 t the N(7/9)-atom yields complexes bearing a protic N-heterocyclic carbene ligand derived from the pu

154 s increase in response was attributed to the protic nature of methanol and the elution of compounds i

155 However, the protic nucleophiles and high temperatures usually requir

156 We interpret this difference in terms of the protic or aprotic character of both nonsolvents, where o

157 rm Ag(I) halide precipitates irrespective of protic or aprotic solvents.

158 e cyclized to the pyrrolodiketopiperazine by protic or gold Lewis acid catalysis.

159 ty and efficacy of various hydride donor and protic or Lewis acid reagent combinations in the reducti

160 thermal reaction conditions; in some cases, protic or Lewis acids accelerate these reactions.

161 afforded epoxides, which, in the presence of protic or Lewis acids, rearranged to dienes or lupanes b

162 ism for optical anion sensing in competitive protic organic and aqueous-organic media.

163 columns in SFC are investigated using both a protic organic modifier (CH(3)OH) and its deuterated cou

164 an (-)-epicatechin conjugate was captured in protic polar nucleophilic methanol alone or methanol-HCl

165 MPO, interacting with the common aprotic and protic polar solvents, CH3CN and CH3CONH2, yielding a pr

166 inolinones exhibit fluorescence (QY ~35%) in protic polar solvents, possibly due to charge transfer,

167 dely available, stable alpha-keto esters and protic pronucleophiles is described (see scheme; X = OR,

168 d by macromolecular cyclization triggered by protic quenching.

169 In the case of protic reagents ((d-) E-H(d+) ), a frustrated Lewis pair

170 ble resistance to attack by nucleophilic and protic reagents.

171 e phases and fraction collection to minimize protic residues for immediate NMR analysis while bypassi

172 determine whether any of the other conserved protic residues is directly involved in the hydratase ca

173 Finally, properly positioned protic sites lead to a substantially increased substrate

174 , a host of polar and apolar groups, various protic sites, and numerous basic functionalities proved

175 ion reaction that, from a single compound in protic solution, results in an equilibrium mixture of fo

176 oxime complexes catalyze H(2) evolution from protic solutions at modest overpotentials.

177 ations considering the effect of a polar and protic solvent (methanol), of a polar and aprotic solven

178 nitromethane and by the poorly nucleophilic protic solvent acetic acid.

179 and products in aprotic solvent, whereas in protic solvent almost full conversions were reached.

180 ong-lived to be characterized by 2D NMR in a protic solvent at ambient temperature.

181 yrroles in the presence of primary amines in protic solvent at ambient temperatures suggests that cov

182 reened six different polar-aprotic and polar-protic solvent combinations to disrupt the H-bonds and h

183 drogen bonds, under conditions of increasing protic solvent concentration.

184 and 67:33, respectively), and the use of the protic solvent ethanol resulted in reversal of the regio

185 -picoline borane as the reducing agent and a protic solvent for the reaction media and has been succe

186 enols to DPPH radical in a non-polar and non-protic solvent have been measured and were found to be i

187 quires the interaction of the carbene with a protic solvent molecule being part of a hydrogen-bonded

188 e number but also the chemical nature of the protic solvent molecule determine which reaction path is

189 omplex between singlet diphenylcarbene and a protic solvent molecule, thus competing with intersystem

190 vestigate the effects of small admixtures of protic solvent molecules, such as water and alcohols, on

191 The resulting polar protic solvent promoted homologation afforded benzylic k

192 of microtubule-bound N-AB-PT was within the protic solvent region, demonstrating that microtubule-bo

193 two side reactions depending on the involved protic solvent species.

194 QMP 9 in a protic solvent undergoes two competitive processes, phot

195 utomer in UV-vis and NMR spectroscopy when a protic solvent was employed.

196 changed from dimethyl sulfoxide/methanol (a protic solvent) to dimethyl sulfoxide (a strongly polar

197 In protic solvent, a molecule of solvent inserts between th

198 upon photoexcitation of 4-6 to S1 in a polar protic solvent, proton dissociation from the phenol, cou

199 In a protic solvent, QMP 6-8 undergo solvent-assisted PT givi

200 kcal/mol and increased by 1.7 kcal/mol in a protic solvent, trifluoroethanol.

201 p-quinonoid like tautomeric forms in a polar protic solvent.

202 intermolecular hydrogen bonds provided by a protic solvent.

203 onstants for each of the individual steps in protic solvent.

204 fluorescence of appended fluorophores in the protic-solvent-inserted form of the boronic acid/boronat

205 In protic solvents (D(2)O and acetic acid-d(4)), hydration

206 Whereas alternative protic solvents (e.g., MeOH vs HFIP) provide products of

207 e solubility of this hemicarceplex in polar, protic solvents (e.g., MeOH).

208 Highly polar protic solvents (hexafluoroisopropanol) favor the format

209 nd have higher fluorescent quantum yields in protic solvents (methanol and water) than the Zn(II)-Pcs

210 ould be obtained only when short alkyl chain protic solvents (methanol or ethanol) and a nonhydrophob

211 e investigated the effect of different polar protic solvents (methanol, ethanol, and isopropanol) as

212 terization, it displayed little stability in protic solvents (t(1/2) = 0.19 h at pH 3, t(1/2) = 0.20

213 ng a "hydrophobic collapsed" conformation in protic solvents and an "extended" conformation in aproti

214 study and measure OH-pi interactions between protic solvents and aromatic surfaces.

215 tone enols point to their high reactivity in protic solvents and explain why no lactone enols have be

216 -hydroxysuccinimide esters are not stable in protic solvents and many biological ligands that would b

217 a of pi-conjugated heterocyclic compounds in protic solvents and other H-bonding environments also il

218 9 has a lifetime of approximately 3000 ns in protic solvents and returns to the starting material thr

219 formation of OH-pi interactions between the protic solvents and the exposed aromatic surfaces in the

220 ree energies of activation for the two polar protic solvents and the gas phase.

221 roup tolerance, and compatibility with polar protic solvents are additional assets of the nickel-cata

222 t transfer of the isocyanide alpha-carbon to protic solvents as a formyl group during imine formation

223 ds, APTES-capped PNCs show high stability in protic solvents as a result of the strong steric hindran

224 (ISC) to the triplet nitrene in aprotic and protic solvents as well as protonation to form the nitre

225 nalyses confirm that the rate retardation in protic solvents comes from loss of hydrogen bonding in p

226 ty of the hydrogen-bonded capsule 1.1 toward protic solvents depends strongly on the guests, with the

227 Protic solvents displayed systematically weaker solvopho

228 mple washing of the resulting materials with protic solvents disrupts the supramolecular association

229 Polar protic solvents exhibited the highest content of total p

230 Removal of polar, protic solvents from these reactions presents environmen

231 Molecular understanding of the role of protic solvents in a gamut of organic transformations ca

232 al ensembles when adding different ratios of protic solvents including an aqueous buffer.

233 benzene, or when the complex is dissolved in protic solvents like methanol (MeOH) or water (H(2)O).

234 The irradiation in protic solvents of 4-chloroalkylbenzenes and 4-chlorophe

235 Binary mixtures of protic solvents show specific interaction effects with r

236 h solvent-derived deuterons in perdeuterated protic solvents such as D(2)O and CD(3)OD.

237 ons (SRI) are prominent in MC ESI spectra in protic solvents such as HPLC grade methanol.

238 with the reduced cobalt(0) precatalysts, and protic solvents such as methanol and isopropanol were id

239 arried out in the presence of water or other protic solvents such as methanol.

240 Guest encapsulation in polar protic solvents such as water appears to be driven by in

241 occurs at a 0.2-A shorter C-N separation in protic solvents than in acetonitrile.

242 es in nucleophilic substitution reactions in protic solvents than in aprotic solvents.

243 uted analogues appear to be more affected by protic solvents than the other analogues.

244 physical property changes in the presence of protic solvents that warrant further consideration.

245 ylamino)pyridine, was studied in aprotic and protic solvents using femtosecond-to-microsecond transie

246 Protic solvents were found to be critical to the success

247 On excitation in polar protic solvents, 2-4 populate charge-transfer states lea

248 he reactions are tolerant of the presence of protic solvents, and approximately 85% of the indium met

249 XB acceptor, due to desolvation penalties in protic solvents, as shown for a tetraquinuclidine XB acc

250 Pc significantly increases its solubility in protic solvents, but a centrally chelated silicon ion an

251 en weak acids (such as ammonium chloride) or protic solvents, can induce racemization, too.

252 to statistical (gauche/trans = 2/1) in other protic solvents, e.g., alcohols.

253 d easy to handle co-oxidant, and fluorinated protic solvents, highly substituted 1-naphthalenones cou

254 In protic solvents, intermolecular interactions appear to d

255 rom tocopheryl radical, whereas in polar and protic solvents, like methanol, no regeneration is obser

256 sponding amines were observed by using polar protic solvents, such as MeOH and (i)PrOH.

257 nging assay carried out in non polar and non protic solvents, such as toluene, BHT regenerates alpha-

258 In protic solvents, the open dipolar intermediate may proce

259 In protic solvents, the shifts are larger because of hydrog

260 However, the RE of CH3Cl is faster in polar protic solvents, which argues in favor of a concerted C-

261 Polar-protic solvents, which have high dielectric constants, r

262 increased linearly with solvent polarity in protic solvents, which is expected due to the nature of

263 ytic cleavage (tau = 108 ps) was observed in protic solvents, while intersystem crossing was observed

264 and 6 show strong fluorescence quenching in protic solvents.

265 ation on both length scales via rinsing with protic solvents.

266 trene are separated by a small energy gap in protic solvents.

267 ereas an "inverse" gap effect is observed in protic solvents.

268 limits of detection are achieved with polar protic solvents.

269 case in which cyclization was spontaneous in protic solvents.

270 trans) using NMR spectroscopy in aprotic and protic solvents.

271 arameters N and s(N) for fluoride in various protic solvents.

272 e allylindium intermediates to hydrolysis in protic solvents.

273 ition of monosaccharides in apolar and polar protic solvents.

274 overall and proceeded more rapidly in polar, protic solvents.

275 ogen-bonded capsule 1.1 and its complexes in protic solvents.

276 s by complete dissociation of the capsule in protic solvents.

277 of a stoichiometric amount of base in polar protic solvents.

278 e unbound analogues form hydrogen bonds with protic solvents.

279 lf-assemble into precursor micelles in polar protic solvents.

280 l for breaking down the barriers existing in protic solvents.

281 nce turn-on occurs when the gel is formed in protic solvents.

282 hindered by the rapid hydrolysis of I(+) in protic solvents.

283 nd are nearly nonemissive in the presence of protic solvents.

284 offset the stronger solvophobic effects for protic solvents.

285 igh thermal and photochemical stabilities in protic solvents.

286 ed by 30 min sonication, especially in polar protic solvents.

287 salts with catalytic amounts of chloride in protic solvents.

288 LutHCl dissociates to give HCl as the active protic source for C-F bond activation.

289 class of ruthenium alkylidenes provided that protic species are available in solution and that the di

290 y a rapid protonation of 3 by water or other protic species.

291 The H(+) in protic state and the Cl(-) together resemble HCl as the

292 A nascent hydrogen bridge between the protic substituent and the polarized [Ru-Cl] unit impose

293 bond to engage in hydrogen bonding with the protic substituent, which helps upload, activate, and lo

294 d scope, which includes unactivated alkanes, protic substrates, basic amines, heterocycles, and keton

295 gen-bonded complexes of 2-aminopyridine with protic substrates] vary depending on the antiaromaticity

296 n the surface charge of silica, an archetype protic surface with a pK value similar to that of acidic

297 Exposing these QDs to protic surface-active compounds RXH, such as fatty acids

298 large rate accelerations in progressing from protic to dipolar aprotic media.

299 The protic version, typically employing trifluoromethanesulf

300 eties, substituents, and leaving groups) and protic vs aprotic solvation.