ライフサイエンスコーパス: proton

1 d by the smallest neurotransmitter possible: protons.

2 generate superoxide for completing the vital proton abstraction step without the need for any externa

3 hamber background pressure affects energetic proton acceleration from an ultra-intense laser incident

4 ications of high-repetition rate laser-based proton accelerators.

5 water molecule, suggesting that the primary proton acceptor for PCET from Y356 and from Y731 is inte

6 ethanolamine (TEOA) was expected to act as a proton acceptor to ensure the sacrificial behavior of 1,

7 y from ubiquinone reduction by NADH to drive protons across the energy-transducing inner membrane.

8 (+)-ATPases (V-ATPase) hydrolyze ATP to pump protons across the plasma or intracellular membrane, sec

9 and biradicals to reference bases with known proton affinities as a function of time in Fourier-trans

10 ragmentation was found to correlate with the proton affinities of the atmospheric molecules studied.

11 eltaE(S-T) = -45 kcal/mol), a high gas-phase proton affinity (PA = 258 kcal/mol), and a preference fo

12 with an inert gas with a substantially lower proton affinity.

13 LUTs can be coordinated with large shifts in proton and chloride concentrations during the synaptic v

14 nized plasma structures supported by trapped proton and electron populations in analogous to the clas

15 relied on classic metal hydrides, where the proton and electrons originate from the metal (via heter

16 uted to the interaction between the hydrated proton and its counterion.

17 is remarkably asymmetric, revealing probable proton and sodium translocation pathways.

18 e the conversion of CO(2) to bicarbonate and protons and are involved in various physiological proces

19 The ready transport of protons and cations through these membranes, and the hig

20 -going developments in laser acceleration of protons and light ions, as well as the production of str

21 igned as the site of interconversion between protons and molecular hydrogen.

22 Initially, these outflows contain only protons and neutrons; these later combine to form alpha

23 to light, generating different mobile acidic protons and thus high on/off photoswitchable proton cond

24 well as mass-transport rates of counterions, protons, and reactants toward catalytically active sites

25 ale (MMS) mission is designed to explore the proton- and electron-gyroscale kinetics of plasma turbul

26 ufficiently high nucleon densities, however, proton- and neutron-scattering processes may alter the e

27 pes of a prokaryotic and a eukaryotic sodium/proton antiporter homologue.

28 The majority of the dose is delivered from protons (approximately 65%-75%) and helium ions (approxi

29 ydrogen gas-evolving hydrogenase (MBH) where protons are the terminal electron acceptor.

30 ciple for constructing molecular wires where protons are translocated over varied distances by a Grot

31 lays a key role in allowing the migration of protons as deuteration is not detected in its absence.

32 rtant kinetic parameters such as the rate of proton-associated chemical steps as well as mass-transpo

33 that cause a relaxation enhancement of water protons at a frequency (1.38+/-0.3 MHz) that is readily

34 ium-binding proteins), pH regulation (V-type proton ATPase), and inorganic carbon regulation (carboni

35 The proton beam can be focussed via target design to achieve

36 Proton beam therapy offers radiophysical properties that

37 Proton beams driven by chirped pulse amplified lasers ha

38 Numerous studies have suggested that this proton binding also prompts a conformational switch, lea

39 th strong inward rectification, BM2 conducts protons both inward and outward.

40 3 to 4 for proton-bound dimers and 3 for the proton-bound 1-octanol trimer.

41 ction improve only by a factor of 3 to 4 for proton-bound dimers and 3 for the proton-bound 1-octanol

42 s and hundred ppt(v) limits of detection for proton-bound dimers measured for a series of ketones.

43 a high-pH resting closed state and a low-pH proton-bound non-conducting state.

44 r ability to spare healthy brain compared to proton broad beams (BBs).

45 The surface propensity of the proton can be attributed to the interaction between the

46 accommodate a variety of guest molecules as proton carriers and to systemically regulate the proton

47 strategy in the rapidly developing field of proton ceramic fuel cells (PCFCs).

48 The voltage-gated Hv1 proton channel is a ubiquitous membrane protein that has

49 Voltage-gated proton channels (H(V)1) are essential for various physio

50 Biological proton channels are sub-1-nm protein pores with ultrahig

51 Herein we report synthetic proton channels fabrication based on sulfonated metal-or

52 Only a few proton channels have been identified so far.

53 ty of sulfonic acid groups mimicking natural proton channels.

54 layers at a rate similar to those of natural proton channels.

55 asure the RRVs of tetrasaccharides, anomeric proton chemical shifts were utilized to predict the corr

56 CO(2) partial pressure (0.1-0.5 bar) and the proton concentration (1-0.25 mM).

57 on carriers and to systemically regulate the proton concentration and mobility within the available s

58 desensitizing current that required a higher proton concentration for activation.

59 boundary of the phase transition due to the proton concentration gradient across the film-depth.

60 at which energy is expended via NNT-mediated proton conductance.

61 the remote-controllable chemical sensors or proton-conducting field-effect transistors.

62 c activity is attributed to the considerable proton conduction, as confirmed by hydrogen permeation e

63 Herein, we report a semiconductive, proton-conductive, microporous hydrogen-bonded organic f

64 t among all COF materials, and maintain high proton conductivity across a wide relative humidity (40-

65 protons and thus high on/off photoswitchable proton conductivity in the hybrid membranes and device.

66 COFs (H(3) PO(4) @COFs) realize an ultrahigh proton conductivity of 1.13x10(-1) S cm(-1) , the highes

67 This device exhibits a high proton conductivity, fast response time, and extremely l

68 Tuning a semiconductor to function as a fast proton conductor is an emerging strategy in the rapidly

69 n of 10 or 30 Gy integral dose using 100 MeV protons configured either as BBs or arrays of 0.3-mm pla

70 se results explain how internal and external protons control intracellular and selectivity filter gat

71 mentally demonstrate a threshold in laser-to-proton conversion efficiency at background pressures [Fo

72 en proton flow beside the well-known inverse proton countertransport occurring in active Ca(2+) trans

73 demonstrated by exploiting the base-assisted proton-coupled electron transfer (PCET) pathway.

74 lease from nitrite at copper(II) following a proton-coupled electron transfer (PCET) pathway.

75 Recently the proton-coupled electron transfer (PCET) rate constants f

76 zation energies associated with electron and proton-coupled electron transfer in the electric double

77 However, the multiple steps associated with proton-coupled electron transfer result in sluggish OER

78 to facilitate the formation of N-H bonds via proton-coupled electron transfer to generate a mu-amide

79 sacrificial electron donors that facilitate proton-coupled electron transfer.

80 The enzymatic O(2) reduction involves proton-coupled electron transfers.

81 ic activation of alcohol O-H bonds through a proton-coupled electron-transfer mechanism.

82 case, we postulate an initial intramolecular proton-coupled electron-transfer step yielding the E1PT

83 and suppresses CAIX-mediated facilitation of proton-coupled lactate transport.

84 Proton-coupled monocarboxylate transporters MCT1-4 catal

85 The mechanisms of proton delivery are incompletely understood, in part due

86 nt as assessed by magnetic resonance imaging-proton density fat fraction (MRI-PDFF) from baseline may

87 tio at 40 Hz, and magnetic resonance imaging proton density fat fraction (MRI-PDFF) in the detection

88 ncreatic and hepatic steatosis quantified by proton density fat fraction (PDFF) on magnetic resonance

89 ient simultaneous T(1) /T(2) relaxometry and proton density mapping in multiple sclerosis.

90 P synthase can readily utilize the localized proton density to drive ATP synthesis.

91 he transmembrane-electrostatically localized proton density to the crista tip where the ATP synthase

92 networks that incorporate the estimation of proton density.

93 directly after autopsy, at 3 T, using T1 and proton-density/T2-weighted, as well as FLAIR, double inv

94 molecular models deepen our understanding of proton-dependent redox chemistry of transition metal oxi

95 Furthermore, 2D proton-detected (1)H-(17)O heteronuclear correlation NMR

96 gnificant sensitivity gains are achieved via proton detection under the conditions of our experiments

97 Correlated with OER activity, proton diffusion is found to be the fastest in the (100)

98 uning the crystal orientation and correlated proton diffusion.

99 rrelated perovskite nickelates by modulating proton distribution under high speed electric pulses.

100 which is positioned to serve as the initial proton donor.

101 can reduce N(2) in the presence of PhOH as a proton donor.

102 will facilitate investigations of different proton dose rates and drugs to ameliorate the cognitive

103 Here, we present a proton-driven nanotransformer-based vaccine, comprising

104 This proton-driven transformable nanovaccine offers a robust

105 stics, the sensor can be used for monitoring proton dynamics in the nucleus.

106 A non-aqueous proton electrolyte is devised by dissolving H(3) PO(4) i

107 d 1,2-mu-peroxo diferric P intermediate, the proton-electron uptake by P is the favored mechanism for

108 (-) spin assignment is needed to explain the proton-emission pattern observed from the T = 3/2 isobar

109 iO(2) to produce scandium radionuclides with proton energies of up to 24 MeV.

110 or transmembrane-electrostatically localized proton energy storage; and 2) The geometric effect of a

111 ations through the electric-field controlled proton evolution with ionic liquid gating.

112 The electron and proton exchange among PEDOT, PSS, and the molecular de-d

113 In a mainstream proton exchange membrane (PEM) fuel cell, platinum-group

114 N-C also exhibits encouraging performance in proton exchange membrane fuel cell, demonstrating great

115 Proton exchange membrane fuel cells have been regarded a

116 This work provides proton exchange membrane fuel cells with enhanced power

117 overed by a 100 to 800 nm thick layer of the proton exchange membrane Nafion.

118 @COFs as the solid electrolyte membrane for proton exchange resulting in a maximum power density of

119 catalysts that are efficient near the acidic proton-exchange layer with those efficient near the alka

120 rgent need to address the high-cost issue of proton-exchange membrane fuel cell (PEMFC) technologies,

121 c electrolytes, which was further studied in proton-exchange membrane fuel cells with encouraging per

122 e oxygen reduction reaction (ORR) cathode in proton-exchange-membrane fuel cells remains a grand chal

123 ormances is one of the major requirements in proton-exchange-membrane water electrolyzers.

124 ulated with voltage-dependent neutral sodium-proton exchanger (NHE).

125 Protons exert their facilitation effect through Ca(2+) -

126 find to be on the order of 0.1 electron per proton; experimentally, we also access this quantity via

127 Proton exposure had the largest effect on activity and p

128 ation, there were no effects on NOR, however proton exposure impaired egocentric (Cincinnati water ma

129 odel of cognitive deficits from conventional proton exposure is needed.

130 n a variety of cellular processes, including proton extrusion, pH regulation, production of reactive

131 of magnitude per pH unit, corresponding to a proton-first mechanism via tyrosinate (PTET).

132 revealing a novel passive cytoplasm-to-lumen proton flow beside the well-known inverse proton counter

133 Proton flow through the F(o) motor generates rotation of

134 of amino acids which is used to regulate the proton flow.

135 erse relaxation values for the water and fat proton fractions and a higher relative %age of the proto

136 The proton from acid dissociation reacts with the halochromi

137 ed on the corelease of neurotransmitters and protons from synaptic vesicles, and is supported by dire

138 nsduces redox energy into an electrochemical proton gradient in aerobic respiratory chains, powering

139 alkane requiring one hydride (H(-)) and one proton (H(+)) equivalent and no added oxidants.

140 ls are sub-1-nm protein pores with ultrahigh proton (H(+)) selectivity over other ions.

141 ng in acidified microenvironments by sensing protons (H(+)).

142 byproduct of PLC-mediated PIP(2) hydrolysis, protons have been shown to play an important role in the

143 ments of tissue oxygen tension (pO(2)) using Proton Imaging of Siloxanes to map Tissue Oxygenation Le

144 reacts by an electrophilic substitution of a proton in an alkane resulting in a B-C bond formation.

145 Additionally, the NH proton in the trifluoroacetamide derivative engages in e

146 This phenomenon results from the active C5-protons in poly(1,2,4-triazolium)s that catalyze the for

147 exchange rate constant (k(ex)) of the imino protons in the unbound, cocaine-bound, and quinine-bound

148 We also examine how proton-induced conformational changes pose unique challe

149 nanoflake clusters, also a known Zn-ion and proton intercalatable material.

150 trostatic potential to establish how and why protons intercalate in V(2) O(5) in aqueous media.

151 Brain cells continuously produce and release protons into the extracellular space, with the rate of a

152 is present in zebrafish sperm and carries a proton inward current that acidifies the cytosol.

153 -scale tensile specimens containing only the proton irradiated volume but approaching the smallest re

154 oped to record stress-strain curves for thin proton-irradiated surface layers of SA-508-4N ferritic s

155 from Cr leaching into the salt is reduced by proton irradiation alone.

156 Proton irradiation is often used as a proxy for neutron

157 , while the translocation of ions, including protons, is efficiently hindered.

158 d with PLS models built on a 60 MHz (for the proton Larmor frequency) spectrometer to predict the spe

159 ice show significantly higher CypD-dependent proton leak and NGSIS compared with lean mice.

160 ed the cyclophilin D-dependent mitochondrial proton leak and uncoupling as a potentially novel subcel

161 Our results uncover the excessive proton leak as a novel mechanism of age-related cardiac

162 icient thermogenic respiration due to futile proton leak in Fmr1 KO mitochondria caused by coenzyme Q

163 me elevates the inner mitochondrial membrane proton leak, leading to increased metabolism and changes

164 closed the channel, blocked the pathological proton leak, restored rates of protein synthesis during

165 Proton leak-mediated NGSIS is conserved in human islets

166 sulin secretion, by increasing mitochondrial proton leak.

167 rt due to an absence of information on exact proton locations and hydrogen bonding structures in a bo

168 which, in turn, provide facile pathways for proton locomotion.

169 e oxidation of MHL(n) is irreversible due to proton loss from the oxidized complex to the solvent.

170 HIO(2)-IONO(2) complex does not exhibit any proton loss to the interfacial water molecules.

171 d healthy older controls (PAH control) using proton magnetic resonance imaging.

172 )F]FMZ-PET) and GABA concentrations by using proton magnetic resonance spectroscopy ((1)H-MRS) in 28

173 IHTG was determined by proton magnetic resonance spectroscopy ((1)H-MRS).

174 hocreatine, or choline compounds measured by proton magnetic resonance spectroscopy suggest that neur

175 LFAT (by proton magnetic resonance spectroscopy) and clinical cha

176 Hepatic fat was measured by proton magnetic resonance spectroscopy, insulin sensitiv

177 Proton minibeams (MBs) comprised of parallel planar beam

178 -grown UWO 241 exhibited increased thylakoid proton motive flux and an increased capacity for nonphot

179 plasm by ATP-powered transport, however, the proton motive force (PMF) is not required to keep P(i) i

180 1, which in complex with ExbB-ExbD links the proton motive force generated across the inner membrane

181 atty acid oxidation (FAO) contributes to the proton motive force that drives ATP synthesis in many ma

182 e H(+) electrochemical potential difference (proton motive force) across the illuminated thylakoid me

183 onse to an inward flow of H(+) driven by the proton motive force, and conformational changes in FliG2

184 Furthermore, the proton-motive force (PMF) across the inner-membrane acts

185 Components of proton-motive force which could impair protein insertion

186 This information sheds light on possible proton movements during heme-catalyzed oxygen activation

187 Background Upper extremity MRI and proton MR spectroscopy are increasingly considered to be

188 hen used in conjunction with multiparametric proton MRI.Published under a CC BY 4.0 license.

189 e to the study of selectivity in other multi-proton/multi-electron electrocatalytic reactions.

190 ases are determined by using slice-selective proton NMR experiments.

191 tained strongly aromatic properties, and the proton NMR spectra showed the N-methyl resonances near -

192 measuring the human faecal metabolome using proton nuclear magnetic resonance ((1)H NMR) spectroscop

193 2D proton nuclear magnetic resonance and SAXS data provided

194 We have compiled a vast resource of proton nuclear magnetic resonance metabolomics and pheno

195 A proton nuclear magnetic resonance metabolomics platform

196 lomics was performed using a high-throughput proton nuclear magnetic resonance metabolomics platform,

197 Offline spectroscopic analysis performed by proton-nuclear magnetic resonance spectroscopy showed th

198 substituents are not tolerated, and the N-H proton of the aniline ring is responsible for the proton

199 r, we investigated the role of intracellular protons on G(i/o) -mediated TRPC4 activation.

200 ides, largely neglecting the contribution of protons, on the basis of computed density estimates.

201 m the stearoyl substrate as compared to the "proton-only activated" pathway.

202 ting anionic intermediates may be trapped by proton or various carbonyl-based electrophiles.

203 ding structures in a bona fide metalloenzyme proton pathway.

204 fractions and a higher relative %age of the proton peak area predominantly from fat at 56 days, matu

205 onse that caps mechanoacid generation at one proton per strained polymer chain.

206 ly site of mediating increased mitochondrial proton permeability in old cardiomyocytes.

207 Key to proton permeation is a methionine residue that interrupt

208 (RP) workflows from the Illumina to the Ion Proton platform and used them to analyze signatures of p

209 This evolution of the proton populations during kneading was interpreted as ch

210 Administration of the proton pump inhibitor omeprazole can reduce both esophag

211 The proton pump inhibitor omeprazole is administered to dogs

212 Lower baseline eGFR, proton pump inhibitor use, and combination immune checkp

213 Proton pump inhibitors (PPIs) are frequently used after

214 Proton pump inhibitors (PPIs) are used for the long-term

215 Proton pump inhibitors (PPIs) or histamine-2 receptor bl

216 of patients with GERD who receive label-dose proton pump inhibitors (PPIs) still have symptoms.

217 Proton pump inhibitors (PPIs), which are commonly used a

218 les of several commercial controlled-release proton pump inhibitors in simulated stomach and intestin

219 Further data integration links proton pump inhibitors to circulating metabolites, liver

220 tegy of stress ulcer prophylaxis with use of proton pump inhibitors vs histamine-2 receptor blockers

221 By contrast, patient age, the use of proton pump inhibitors, and the use of primary prophylax

222 Therapies include proton pump inhibitors, elimination diets, and topical c

223 In AIG, the gastric proton pump, H(+)/K(+) ATPase, is the major autoantigen

224 Strikingly, the proton-pump inhibitor omeprazole similarly altered the m

225 /MM) free energy calculations to explore how proton pumping reactions are triggered within its 200 an

226 A mechanism for the proton pumping, involving a specific and crucial role fo

227 lycolysis is essential for V-ATPase-mediated proton pumping.

228 ane subunits are found to be responsible for proton pumping.

229 a trimer arrangement reminiscent of BR-like proton pumps and shows features at the extracellular sid

230 we investigated the function of two types of proton pumps in Arabidopsis embryo development and patte

231 Proton pumps were divided into two subtypes (DTEW and DT

232 Proton radiotherapy (PRT) may lessen the neuropsychologi

233 To reduce adverse effects of proton radiotherapy, a model of cognitive deficits from

234 rugs to ameliorate the cognitive sequelae of proton radiotherapy.

235 New insights into the mechanism of N(2) and proton reduction are first considered.

236 ction and suppresses hydrogen evolution from proton reduction, leading to Faradaic efficiencies close

237 n crystallization kinetics and water and fat proton relaxation were studied in water-in-milk fat emul

238 We identify a proton-relay pathway for ubiquinone reduction and water

239 A solid proton reservoir layer, PdH(x), also serves as the gate

240 imes larger Gd neutron captures per GyE than protons, respectively.

241 The insertion of protons results in a large structural expansion and incr

242 (CO)(24)](4-) in the presence and absence of protons reveals ET kinetics and diffusion behavior simil

243 esis of heavy elements in the Ga-Cd range in proton-rich neutrino-driven outflows of core-collapse su

244 The aim of this study is to identify proton sensors in the rat pituitary gland.

245 Located adjacent to proton shuttle residue Ser(130), it is suggested to play

246 change process was found to be mediated by a proton-shuttling agent such as water, a second IBX, or a

247 me previous assignments, and assigning a new proton signal as an alcohol.

248 isphosphate (PIP(2) ) to produce the initial proton signal that triggers a self-propagating PLCdelta1

249 ith acetyl chloride clarified assignments of proton signals, confirming some previous assignments, an

250 s the differentiation of several spiroglycol proton signals.

251 ased inhibitors by comparing hydrated excess proton stabilization during proton transport in M2 with

252 This example of metal/ligand proton tautomerism is unusual in that the position of th

253 d between them and also with the traditional proton therapy to evaluate their impacts before the expe

254 magnetic coupling between glycogen and water protons through the nuclear Overhauser enhancement (NOE)

255 al processes are governed by the transfer of protons to the surface, which can be coupled with electr

256 l simulations show how the structures funnel protons to the tight focus.

257 t to be reached on the route taken by pumped protons to traverse CcO's hydrophobic core and on whethe

258 The calculations revealed a local electron-proton transfer (LEPT) state, in which both the electron

259 ctrochemistry, which suggests a stepwise one proton transfer (PT) and two electron transfer (ET) proc

260 al of DDD-AAA H-bond dimers, consistent with proton transfer across the central H-bond upon reduction

261 Phenols and quinols participate in both proton transfer and electron transfer processes in natur

262 initiate polymerization and facilitate rapid proton transfer between active and dormant chains.

263 Ser(130), it is suggested to play a role in proton transfer during catalysis of the antibiotics.

264 methylammonium lead bromide, which induces a proton transfer from methylammonium to benzylamine and e

265 ansfer from the phenol to the anthracene and proton transfer from the phenol to the pyridine, forming

266 (LEPT) state, in which both the electron and proton transfer from the phenol to the pyridine.

267 been experimentally determined by monitoring proton transfer from the protonated mono- and biradicals

268 transfer from tyrosine to Ru(bpy)(3)(3+) and proton transfer from tyrosine to a hydrogen phosphate di

269 olves the unprecedentedly fast multiposition proton transfer in the intermediate adducts of acetylene

270 nprecedented detail, including the degree of proton transfer in the transition state.

271 PR(2)) group on an unsaturated substrate and proton transfer involving the metal hydride yields the p

272 anion followed by barrierless intramolecular proton transfer leads to the final product.

273 Importantly, the electron and proton transfer pathways in [FeFe]-hydrogenases are well

274 ures, these findings enable us to follow the proton transfer process of the entire acylation reaction

275 ng-field ionization and to track the primary proton transfer reaction giving rise to the formation of

276 ied, together with multiple VOCs measured by proton transfer reaction time-of-flight mass spectrometr

277 Furthermore, the order of the associated two proton transfer reactions is predicted to be different i

278 , to inhibit the progression of ion/molecule proton transfer reactions, the product ions must be remo

279 s on the long-range coupling of electron and proton transfer steps.

280 ermolecular chemical step involving a second proton transfer to give the E2PT product.

281 und I (i.e. FeO(3) (+)) or, alternatively, a proton transfer-independent nucleophilic ferric peroxo a

282 s trans-to-cis chromophore isomerization and proton transfer.

283 rom total lipid extracts utilizing gas-phase proton-transfer ion/ion reactions.

284 e, 2,3-hexanedione, octanal and linalool) by proton-transfer-reaction mass spectrometry (PTR-MS).

285 headspace experiments on pig manure, we used proton-transfer-reaction mass spectrometry and cavity ri

286 zed by near-infrared-spectrometry (NIRS), by proton-transfer-reaction time-of-flight mass-spectrometr

287 synthase was coreconstituted with an active proton-translocating cytochrome oxidase, ATP synthesis r

288 hanism where the coupling between sodium and proton translocation is facilitated by a series of elect

289 e likely to represent the first steps in the proton translocation mechanism.

290 hanistically crucial elements and constitute proton-translocation pathways through the membrane.

291 imic membrane proteins and exhibit selective proton transport across lipid bilayers at a rate similar

292 ting Ca(2+), SERCA facilitates bidirectional proton transport across the sarcoplasmic reticulum to ma

293 We find that proton transport from the central binding site to the lu

294 hydrated excess proton stabilization during proton transport in M2 with the interactions revealed in

295 value close to that previously reported for proton transport(11,12).

296 geting, packaging, nucleocapsid binding, and proton transport.

297 here electrochemically generated formate and proton were recombined to form molecular formic acid.

298 y produce significant amounts of lactate and protons, which are exported via monocarboxylate transpor

299 Unlike influenza A M2 (AM2), which conducts protons with strong inward rectification, BM2 conducts p

300 he channel to transport and stabilize excess protons, with critical implications for future drug desi