ライフサイエンスコーパス: protract

1 se the timeline for LF in this setting seems protracted.

2 not quantitative, lack sensitivity, and are protracted.

3 everal weeks, and the course of infection is protracted.

4 accine candidates are commonly laborious and protracted.

5 ced swim test (FST) is revealed only after a protracted (2 weeks), but not acute (24 h), abstinence p

6 hours), short-term (3 consecutive days), and protracted (7 days after the last of three consecutive d

7 It then persists into protracted abstinence and contributes to the development

8 Hyperkatifeia can extend into protracted abstinence and interact with learning process

9 The effects of protracted abstinence following long-term ethanol self-a

10 rug-paired stimuli following 2 or 5 weeks of protracted abstinence from chronic drug exposure as comp

11 ibutes to increased motor impulsivity during protracted abstinence from long-term alcohol exposure.

12 hdrawal symptoms during acute withdrawal and protracted abstinence in rats previously exposed to chro

13 this model a hyperdopaminergic state during protracted abstinence is associated with vulnerability f

14 withdrawal signs, whereas anxiety linked to protracted abstinence is attenuated by pioglitazone inje

15 inistration during both acute withdrawal and protracted abstinence test sessions, whereas KOR antagon

16 l, whereas excessive anxiety associated with protracted abstinence was prevented by pioglitazone micr

17 anticipatory signals recover or adjust after protracted abstinence will be important in understanding

18 al transcriptional regulatory network during protracted abstinence, a period when relapse rates are h

19 s in alcohol dependent patients in early and protracted abstinence, and in comparison with control su

20 During early withdrawal and protracted abstinence, the expression of PPARgamma incre

21 a phenocopy of alcohol-dependent rats during protracted abstinence.

22 f-administration during acute withdrawal and protracted abstinence.

23 rawal assessment during acute withdrawal and protracted abstinence.

24 d and stress systems are dysregulated during protracted abstinence.

25 e preference when drug is experienced during protracted abstinence.

26 itioned for morphine place preference during protracted abstinence.

27 of orexin neurons for morphine reward during protracted abstinence.

28 The epibatidine analogs produced protracted activation of high sensitivity (HS) alpha4- a

29 y and liver injury due to early, robust, and protracted activation of NF-kappaB in the absence of bet

30 model further suggested that the relatively protracted activation of the RAF-MEK1/2-ERK1/2 module, i

31 erapeutic strategies for mycosis require the protracted administration of antifungals, which can resu

32 Such protracted aggregation has profound implications for our

33 on favors mature B cell cancers by eliciting protracted AID expression in GC B cells.

34 eceptor in excessive alcohol drinking during protracted alcohol abstinence.

35 re (AIE) on negative affect during acute and protracted alcohol withdrawal and following stress in ad

36 the underlying neurobiological substrate for protracted amygdala growth into adulthood is unclear, we

37 on of lineages that originated owing to more protracted and complex interactions between biological a

38 evelopment of the eye, potentially replacing protracted and costly multidisciplinary assessments and

39 formation with standard methods is typically protracted and inefficient, resulting in heterogeneous c

40 fires were also present but more delayed and protracted and likely played a less acute role in biotic

41 sition to agriculture in southwest Asia as a protracted and multiregional process.

42 The identification of the isolate was protracted and ultimately dependent upon sequence analys

43 e expectancy and the dying trajectory can be protracted and unpredictable.

44 (BLA), neuropeptide Y (NPY) buffers against protracted anxiety and fear.

45 otent signature in early embryos, there is a protracted appearance of a primed signature in advanced

46 But political instability and protracted armed conflict, with significant disruption o

47 The protracted arrest in meiotic prophase makes oocytes part

48 small leucine-rich proteoglycan, initiates a protracted autophagic program downstream of VEGF recepto

49 ht chain 3 alpha genes, thereby leading to a protracted autophagic program.

50 s to bacterial coinfection, in children with protracted bacterial bronchitis (PBB) and mild bronchiec

51 Acute SARS-CoV-2 infection leaves protracted beneficial (ie, activation of T cells) and po

52 ng in a flood of new molecular insights into protracted biological questions.

53 subconductance states, with B-973B producing protracted bursts, even in the presence of mecamylamine.

54 of Cambrian Series 2 (~521 Ma), suggesting a protracted but cryptic earlier history that possibly ext

55 This process of protracted but episodic erosion of legacy sediment and a

56 tles was not temporally synchronized but was protracted by several decades, compared with stand devel

57 eliminates the basis for earlier theories of protracted childhood and prolonged post-menopause longev

58 s for severe seasonal influenza and the more protracted clinical course compared with that of H5N1 su

59 The protracted clinical course of the MPNs has limited the u

60 The majority of patients show a protracted clinical course with persistent disease.

61 Due to their protracted clinical course, the evolution to advanced he

62 aparesis, dementia, blindness) and different protracted clinical forms of GM1- and GM2-gangliosidoses

63 versity in inactive genes is indicative of a protracted clonal evolution and consequently, increased

64 d people with missing doses, and despite the protracted collection of interview information necessary

65 (2.5 min), transient (peaks at 15 min), and protracted compared with receptor tyrosine phosphorylati

66 Protracted conflicts in the Middle East have led to succ

67 Finally, alongside protracted conflicts, widening of health and socioeconom

68 it is crucial to highlight the immediate and protracted consequences of cannabis exposure on pre- and

69 Memories of frightening events require a protracted consolidation process.

70 nd the established adverse effect profile of protracted corticosteroid use, this analysis substantiat

71 ith detectable food-specific IgE, can have a protracted course and eventually transition to acute rea

72 immunodeficiency virus (HIV) may have a more protracted course.

73 th obinutuzumab for follicular lymphoma with protracted COVID-19 and viremia.

74 a very promising approach in the context of protracted COVID-19 symptoms in patients unable to mount

75 n assumptions that do not fit the context of protracted crises.

76 Ordovician extinctions, our study suggests a protracted crisis interval linked to intense volcanism d

77 long-acting methods, are available, even in protracted crisis settings.

78 Plutons are formed by protracted crystallization of magma bodies several kilom

79 oimmune diseases, but the standard method is protracted, cumbersome and prone to error.

80 I interferon response initially, but also a protracted cytokine response after seroconversion, marke

81 With protracted damage, fibrosis can progress toward excessiv

82 vere cognitive and physical impairments, and protracted deaths in the hospital setting.

83 solutions that may easily become enmeshed in protracted debate and controversy as they encounter the

84 We measured pupil size while subjects formed protracted decisions about the presence or absence ("yes

85 These data indicate a protracted decline in occupation within the economic and

86 stically, 5hmC enrichment is followed by its protracted decline thereafter at a rate consistent with

87 a multi-hour circulation half-life, offering protracted delineation of vasculature.

88 ry as an exemplar case (given this network's protracted development across these ages).

89 s in the paralaminar nuclei (PL), suggesting protracted development and possibly neurogenesis.

90 Critically, protracted development contributes to the plasticity of

91 putational and neural mechanisms, which show protracted development in childhood and are affected by

92 he face perception task was driven mainly by protracted development in identity perception, while gaz

93 ent of PSD-95 and GluA2 into late childhood, protracted development of GluN2A until approximately 40

94 ation might be improved by accommodating the protracted development of human neural cells.

95 n of error-processing abilities supports the protracted development of inhibitory control over adoles

96 The protracted development of structural and functional brai

97 The protracted development of the cortex and its connections

98 We used RNA-seq and exploited the protracted development of the parasitic nematode Ascaris

99 uisition of these functions is linked to the protracted development of the prefrontal cortex (PFC) an

100 gyrus (DG) is a unique cortical region whose protracted development spans the embryonic and early pos

101 This protracted development was specific to first-person pers

102 tic inhibition mediated by PVINs undergoes a protracted development, it does not exhibit a fear behav

103 The human cerebellum has a protracted developmental timeline compared with the neoc

104 old, in order to study play contagion over a protracted developmental window.

105 The microbiologic causes of protracted diarrhea include detectable parasitic (eg, Gi

106 s, but how we respond to them can range from protracted disability to resilience and growth.

107 ducation were associated with higher risk of protracted disability.

108 opy of Mecp2 (Mecp2(ZFN/+)) displayed a more protracted disease course.

109 s in effective population size due to both a protracted domestication bottleneck and serial founder e

110 nd its wild relatives, suggesting a gradual, protracted domestication process.

111 Interestingly, asymmetry develops in a protracted dorsoventral wave, whereas lamination does so

112 Before protracted drug exposure, most rats prefer natural rewar

113 with alterations in reward valuation during protracted drug withdrawal.

114 larger entity, but elimination may still be protracted due to incomplete dispersion of gold.

115 sistent with a basic emotion, especially its protracted duration and frequently cold phenomenology.

116 jor psychoactive component of cannabis, with protracted effects on adult neural systems relevant to p

117 CBD also showed significant protracted effects on these measures 7 days after the fi

118 Here we show that this protracted EN event, combined with the regional warming

119 Antibodies to DPPX are associated with a protracted encephalitis characterized by central nervous

120 These data demonstrate that protracted endogenous fibrinolysis induced by TBI is pri

121 Using protracted episodic expression of Omomyc, we now demonst

122 Protracted exposure of neurons to stress led to neurotox

123 We show that protracted exposure to kin or non-kin odorants changes t

124 mated relative risks of CLL and non-CLL from protracted exposures to low-dose ionizing radiation.

125 on are well known, but risks associated with protracted exposures, as well as associations between ra

126 ction-related memory processes suggests that protracted extinction training following brief cue-elici

127 tor activity that is either too brief or too protracted fails to sufficiently open T-type channels ne

128 All the patients with protracted fecal HEV shedding during treatment suffered

129 nodules is time-consuming and often leads to protracted follow-up with ongoing radiological surveilla

130 e changes in gene expression associated with protracted forced abstinence.

131 In NSCs, OxPhos dysfunction leads to a protracted G(1)/S-phase and results in delayed temporal

132 tion of septum formation and a significantly protracted G1 arrest.

133 eath after selinexor treatment occurs from a protracted G1-phase and early S-phase.

134 Public health officials investigated a protracted GAS outbreak in a skilled nursing facility in

135 Protracted glucocorticoids exposure during pregnancy can

136 Furthermore, [dA(2)]GLP-1/GcG elicited a protracted glucose-lowering and insulinotropic effect in

137 ce cue receptor, controls the extent of this protracted growth by determining where and when dopamine

138 ation in the amygdala follows the pattern of protracted growth in TD and early overgrowth in ASD and

139 arth masses within <1 My, followed by a more protracted growth to approximately 50 Earth masses until

140 ly applied to inform real-time operations in protracted health emergencies.

141 itry and determined how they interact with a protracted history of cocaine self-administration.

142 For the most protracted hot and dry events, the strongest and most wi

143 valuation II at admission (<20) and prone to protracted ICU stay may benefit most from rehabilitation

144 ight for the prolonged viral replication and protracted illness observed in H5N1-infected patients.IM

145 ralized T cell paralysis as a major cause of protracted immune suppression from sepsis.

146 ng features of hyperinflammation, as well as protracted immune suppression.

147 ase but little is known regarding a possible protracted impact of COVID-19 on the adaptive and innate

148 mented by cocaine administration and is more protracted in rats that were permitted to receive the dr

149 ommitment of CML cells to apoptosis requires protracted incomplete restoration of BCR-ABL signaling m

150 ber formation, and produced an amplified and protracted increase in endothelial permeability in respo

151 ministration group was distinguished by more protracted increases in adrenocortical activity compared

152 s (CTLs) play an important role in resolving protracted infection with hepatitis B and C virus in hum

153 The protracted infertility observed in PZP-treated horses ma

154 Specifically, protracted inflammation after acute injury has been asso

155 Protracted inflammation may result in aberrant adenosine

156 eficiency virus (HIV) infection is driven by protracted inflammation; the primary loss of CD4(+) T ce

157 Despite this protracted interval of core formation, the iron meteorit

158 nce times for FK228 at HDAC1, explaining the protracted intracellular behaviour of this prodrug.

159 ell imaging revealed that death occurs after protracted loss of OM material through vesiculation and

160 Transcriptomic analysis showed that during protracted low-grade H(2)O(2) stress, Escherichia coli r

161 uced alveolar fraction which corresponded to protracted lung inflammation.

162 ropriate behavioral responses, develops in a protracted manner and is compromised in several prevalen

163 g a pyrin domain 3 (NLRP3) inflammasome in a protracted manner, leading to an up-regulation of IL-1be

164 g a globally diachronous biotic turnover and protracted mass extinction event.

165 cingulum bundle may play a critical role in protracted maturation of executive functioning.

166 ortex (DLPFC) and appear to arise during the protracted maturation of this circuitry across childhood

167 of amygdala-mPFC circuitry may underlie the protracted maturation of threat regulatory processes.

168 gest that the mesofrontal circuit exhibits a protracted maturation through adolescence.

169 than anything previously observed following protracted MD in cat, and they highlight a possibility f

170 in patients upon proinflammatory challenge; protracted modulation of the inflammatory environment is

171 This protracted, multistage process for the production and st

172 s of satellite cells and exhibit delayed and protracted muscle regeneration, and satellite cell-deriv

173 t Asia by highlighting the multiregional and protracted nature of plant domestication.

174 The protracted nature of seafloor methane emissions probably

175 al expansion has recently been attributed to protracted neurogenesis by outer radial glial cells in t

176 valuated whether HMGB1 antagonism blocks the protracted neuroinflammatory and sickness response to pe

177 tinued expression of DCX in brain areas with protracted neuron recruitment has promoted this endogeno

178 ogenitor decommissioning are co-regulated in protracted neuronal lineages.

179 eatment regimen (especially in patients with protracted neutropenia), and how long to continue antimi

180 etry of the distal part of the ovipositor by protracting one valve set with respect to the other.

181 phoebe song unexpectedly develops through a protracted ontogeny.

182 with initial DFU cultures yielding MRSA and protracted open ulcers had a high 24-month cumulative pr

183 Protracted opiate withdrawal is accompanied by altered r

184 monstrated a role for large SPSSs in chronic protracted or recurrent HE and substantiated the effecti

185 or antagonist preserves choroid and prevents protracted outer neuroretinal anomalies in OIR, suggesti

186 combination of these factors may explain the protracted oxygenation of Earth's surface over the last

187 The protracted path toward Gavi support for TCV highlights t

188 of a coarse-grained model system reproduced protracted pausing and stalling, which suggests that the

189 Using protracted PC_DCN activation (120 s) to mimic background

190 clude that naked mole rats show an extremely protracted period of brain maturation that may permit pl

191 Studies using mouse models of ALS indicate a protracted period of disease development with progressiv

192 arly cancer cell dissemination followed by a protracted period of dormancy potentially explains this

193 between these warblers likely results from a protracted period of hybridization, contradicting the br

194 The Late Devonian was a protracted period of low speciation resulting in biodive

195 dell seal, a long-lived marine mammal with a protracted period of maternal care during which mothers

196 approximately 3,500 years ago, suggesting a protracted period of population size reduction likely co

197 ganglion cell connectivity undergoing a more protracted period of refinement.

198 epoch of nonspecific responses followed by a protracted period of taste-specific firing.

199 on the DNA behind the replication fork for a protracted period of time, allowing them to form a docki

200 imate cortical progenitors proliferate for a protracted period of time, during which they generate ea

201 holinergic neurons in the ENS develop over a protracted period of time.

202 s modulate the activity of POMC neurons over protracted periods of time.

203 es in 2050-2069 peak stream temperatures and protracted periods of warming from May to September (MJJ

204 erapies must target both the initial and the protracted phase of the syndrome to relieve early immuno

205 of the amygdala (BLA), which correlates with protracted plasma corticosterone release.

206 in this time frame, suggesting that the more protracted post-ictal state cannot be explained by persi

207 in determining human health risk in space or protracted post-treatment normal tissue toxicity.

208 layed cognitive development in children, and protracted postinfectious syndromes.

209 The protracted postnatal development of sparse, selective fi

210 ructures, and this trend likely reflects the protracted postnatal development of the cortex.

211 man traits, including exceptionally slow and protracted preadult growth.

212 Although protracted prefrontal gray matter development is associa

213 idation Event (GOE) is currently viewed as a protracted process during which atmospheric oxygen incre

214 Despite (and perhaps because of) a protracted process of deliberation and argument about wh

215 ication - that in general domestication is a protracted process, that unconscious (natural) selection

216 During postnatal development, there was a protracted, progressive sparsification of responses, acc

217 epidemiological investigation suggested that protracted radiation exposure increases radiation-induce

218 ses in water and temperature stress that are protracted, rapid, or both, drive a gradient of tree str

219 g embolic chemoembolization as predictors of protracted recovery because of postembolization syndrome

220 The protracted recovery of CFA motor performance demonstrate

221 extinction mechanism and explanation for the protracted recovery period, yet the vertical distributio

222 However, protracted recruitment of stress systems can precipitate

223 has become a focus in recent years, but the protracted recurrence of disease and unknown adverse ocu

224 ing regular marijuana use but decreased with protracted regular use.

225 ptor demonstrated a unique role for GID1a in protracted response to GA that was saturated only at hig

226 rsive tastes, high spontaneous firing rates, protracted responses, and broader tuning.

227 We find that neurons with protracted resting temporal receptive fields exhibit str

228 hexol) nanoparticles exhibited substantially protracted retention within the tumor bed and a 36-fold

229 took part in a memory retrieval task with a protracted retrieval trial consisting of an initial memo

230 ucture involve either spatially resolved but protracted scanning probe experiments without real time

231 d slowly declines over 20 min to support the protracted secretory response.

232 sistent with recovery of immunocompetence in protracted sepsis.

233 ng nodes that facilitate AXL-RTK cross-talk, protracted signaling, converging on ERK, and PI3K axes.

234 diversity, but little is known about how the protracted spatial dynamics of this transition impacted

235 In conclusion, the protracted spread of pandemic influenza in fall 2009 in

236 reaction, if not treated early, shifts to a protracted state of immunosuppression that alters both i

237 f the stabilized step function opsin (SSFO), protracted stimulation of the SC was achieved with only

238 After protracted stimulation, the beta2-adrenergic receptor an

239 Protracted stress primed enhancers for rapid increases i

240 Together, our results demonstrate that protracted subversion of immune dynamics contributes to

241 among the majority of human pregnancies, to protracted surface area alterations, that preferentially

242 subsequent unscheduled physician encounter, protracted symptoms, crossover, and 3% or more weight lo

243 o an increase in E and I synapse density and protracted synapse maturation, traits characterizing hum

244 T19, recognized leukemic blasts, established protracted synapses, and eradicated CD19-negative leukem

245 Mice of TCL1A-initiated protracted T-PLL development resembled such features.

246 llosteric activation by B-973B appeared more protracted than that produced by GAT107, and B-973B resp

247 motoneurons that drive intrinsic muscles to protract the vibrissae receive a short latency inhibitor

248 This preferential binding protracted the depolymerization kinetics of Lys48-linked

249 nhibits all identified functions of SRGAP2A, protracting the maturation and increasing the density of

250 However, when rats run at high speed, they protract their whiskers in front of the snout without la

251 miliarity, however, they moved more rapidly, protracted their whiskers further, and showed decreased

252 tionally blind animals moved more slowly but protracted their whiskers further.

253 replicating mycobacteria responsible for the protracted therapy required to cure tuberculosis.

254 m hypothesis to obtaining the results can be protracted, thus limiting the number of compounds that c

255 and between organoids that can change over a protracted time course of differentiation.

256 ectly with soluble compounds and, for a more protracted time, through alteration, processing, and rel

257 lying affective learning capitalizes on this protracted timeline to develop a rich affective repertoi

258 d in meningoencephalitis and death on a more protracted timeline, 1 to 2 weeks after initial OROV or

259 response upon reexposure to antigen even at protracted times postinfection.

260 However, the protracted timing of human neuron specification and func

261 atmosphere, emphasizing the strong role the protracted transmission of catchment responses to distan

262 in mouse pluripotent stem cells compared to protracted trends in human pluripotent stem cells.

263 polymeric prodrug resulted in increased and protracted tumor drug exposure compared with CPT-11, lea

264 nefit from decades of research but are often protracted, unamenable to diversification, and reliant o

265 ent with Sigma1 ligands, which suggests that protracted UPR results in autophagy as a secondary respo

266 Nonetheless, (11)C-GR103545 displays protracted uptake kinetics and is not an optimal radiotr

267 The recurrent and protracted use of antiviral drugs with eventual emergenc

268 einforcing effects of abused drugs, but with protracted use the dorsolateral striatum is thought to a

269 excessive drug intake that emerges following protracted use.

270 ors had a history of either ocular trauma or protracted uveitis.

271 derwent fewer tracheostomies and episodes of protracted ventilation.

272 less snow resulted in longer lags and a more protracted vernal window.

273 In the face of chronic cancers and protracted viral infections, human immune cells are know

274 ntional therapies to stimulate recovery from protracted visual deprivation.

275 Protracted war and armed conflicts have displaced popula

276 e evolution of Arctic polar climate from the protracted warmth of the middle Pliocene into the earlie

277 whisker positions in the turn direction and protracted whisker movements on the other side.

278 changed in concert with running so that more protracted whisking was correlated with faster running.

279 viscously relaxed or that Ceres experienced protracted widespread resurfacing.

280 found collapse prior to axon termination is protracted, with the growth cone transitioning from a dy

281 HT sensitivity, which partially recovered in protracted withdrawal (2 weeks).

282 Alcohol dependence and protracted withdrawal did not alter either 5-HT1A-mediat

283 s into how both chronic alcohol exposure and protracted withdrawal dysregulate 5-HT signaling in the

284 dU cells, and methamphetamine seeking during protracted withdrawal enhanced Fos expression in the den

285 tion mediate resistance to extinction during protracted withdrawal from a history of extensive cocain

286 Protracted withdrawal from cocaine experience increases

287 in cell number and activity persisted during protracted withdrawal from cocaine for at least 150 days

288 Exposure to predator odor during protracted withdrawal from intermittent alcohol drinking

289 Protracted withdrawal from self-administration enhanced

290 split effects (increase and decrease) after protracted withdrawal indicative of neuroadaptations of

291 use, and typically sudden onset, severe, and protracted withdrawal symptoms when medication was stopp

292 perglutamatergic state within the NAC during protracted withdrawal, characterized by elevated metabot

293 After protracted withdrawal, cocaine-experienced animals exhib

294 l of DA neurons by tVTA is maintained during protracted withdrawal, the capacity for disinhibitory co

295 inhibition of VTA DA neurons observed during protracted withdrawal.

296 behavioral responses to predator odor during protracted withdrawal.

297 ession in the nucleus accumbens core after a protracted withdrawal.

298 seeking akin to cocaine-experienced rats in protracted withdrawal.

299 f the CeA 5-HT system to chronic alcohol and protracted withdrawal.SIGNIFICANCE STATEMENT Elevated GA

300 The reestablishment of widespread and protracted WPV1 transmission in the DRC and Angola follo