ライフサイエンスコーパス: prove

1 t cancer (MCF-7) and melanoma (SK-MEL-5) was proven.

2 Namely, in aqueous media, we prove a near-surface desolvation of lithium ions from th

3 o exclusively target capillary pericytes may prove a precise and potentially powerful tool to treat m

4 dendritic remodeling of NAc D1-MSNs and may prove a useful target for new depression therapeutics.

5 H(2) S may prove a useful therapeutic agent to protect the human fe

6 ectrophotometric method, the UPLC/FLR method proved a sensitive and specific method of quantification

7 quencing performed on the same heart samples proved a subset of haQTLs to have significant associatio

8 cfDNA, measured by a rapid simple assay, proved a valuable early marker of severity in ABP with c

9 Accelerometry has proven a powerful tool to estimate energy expenditure, b

10 Of all 92 QFT-G-positive patients, culture-proven active TB was observed in 1 case.

11 generators described here are true textiles, proving active thermoelectrics can be woven into various

12 Eleven cases of pathologically proven acute gangrenous cholecystitis and 12 consecutive

13 titis and 12 consecutive cases of surgically proven acute non-gangrenous cholecystitis that underwent

14 aHR, 1.68 [1.08-2.62]; P = 0.022) and biopsy-proven acute rejection (aHR, 1.71 [1.13-2.60]; P = 0.012

15 Biopsy-proven acute rejection (BPAR) rates and types were compa

16 ults for mTORi versus MPA in terms of biopsy-proven acute rejection (hazard ratio [confidence interva

17 ary endpoints were treatment failure (biopsy-proven acute rejection, graft loss, or death), delayed g

18 of GDF15 to an increased incidence of biopsy-proven acute rejection.

19 3 [4.7%] vs 17 [21.9%], P = .007) and biopsy-proven acute rejections (15 [23.4%] vs 31 [48.4%], P = .

20 n addition, material from a range of autopsy-proven ageing-associated and primary tauopathies in whic

21 static embolisation for the treatment of BPH proved an effective and safe technique in patients who w

22 ility, and increased NA/DMA biosynthesis has proved an effective Fe biofortification strategy in seve

23 The incidence of probable/proven and possible CAPA in this subset of patients was

24 There is no proven antiviral or immunomodulatory therapy for coronav

25 he concept of "memory of chirality" has been proven as a powerful tool in asymmetric synthesis, while

26 IDP' in view of clinical similarity, but not proven as yet.

27 Culture-proven aspiration pneumonia and early-onset ventilator-a

28 NaCl might therefore prove beneficial for the treatment of chronic inflammato

29 ients that did not receive them and they may prove beneficial in the most severe cases by reducing th

30 However, these studies are unable to prove biologic plausibility and causality as randomized

31 ose with persisting BKPyV-DNAemia and biopsy-proven BKPyVAN, who would benefit from individualized th

32 of therapeutic intervention and diagnosis of proven BKPyVAN.

33 ths and the material efficacy and safety was proven both in vitro and in vivo.

34 col used to remove Fmoc from Gly residue was proved by the synthesis of Leu-enkephalin.

35 ma cell line with high metastatic potential, proven by a xenotransplant in zebrafish larvae, we have

36 tinct types of SCMs are identified, and then proven by computational construction.

37 The feasibility of the methods was proven by investigating restricted diffusion of water in

38 packings comprising dry small particles, as proven by X-ray nanotomography.

39 management of the patient with suspected or proven cardiovascular complications of coronavirus disea

40 (AD) has long been an area of interest, but proving causality has been elusive.

41 To prove causation, it will be necessary to decipher which

42 However, understanding their biology has proved challenging due to their large size, long lifecyc

43 on and tissue morphogenesis; however, it has proved challenging to directly measure strain at high sp

44 that play a role in associative memories has proved challenging.

45 he effects of these degradation products has proven challenging because of the complexity, transience

46 or limiting viral spread and disease, it has proven challenging to develop targeted and selective the

47 However, RTs have proven challenging to discover and engineer, in particul

48 tion of a broad range of targets, but it has proven challenging to fabricate suitable three-electrode

49 of stem cell-related signaling pathways has proven challenging.

50 Islamic transition, testing this theory has proven challenging.

51 afenib remained the only systemic agent with proven clinical efficacy for patients with advanced HCC.

52 There are no antiviral drugs with proven clinical efficacy for the treatment of COVID-19,

53 Single-agent immune modulators have thus far proven clinically ineffective, and multi-modal therapies

54 showed complete degradation within 46 days, proving composting to be a feasible waste stream option

55 ure data for biological macromolecules often prove critical to dissecting and understanding the preci

56 As a result, the reaction proved critical in achieving total syntheses of two oxyg

57 ells in reducing cell volume, an effect that proved crucial in facilitating migration across the tigh

58 oses on biopsy, adding support for pathology-proven data to guide treatment in relevant cases.

59 of asymptomatic carotid artery stenosis has proved difficult over the last decade.

60 e key to its function, and this behavior has proved difficult to characterize at a structural level d

61 However, it has proved difficult to constrain the extent of the primary

62 However, it has proved difficult to obtain cryo-EM reconstructions with

63 The basis of this disease heterogeneity has proved difficult to resolve due to poor tumor cellularit

64 -like architectures in living cells, but has proven difficult due to the lack of control over defined

65 However, such reactivity has proven difficult to reproduce in solution with man-made

66 cision is correct-known as metacognition-has proven difficult to study in isolation as it usually coo

67 a direct pharmacologic manner and thus have proven difficult to target in the clinic.

68 ic role of TRIM32 in LGMD2H pathogenesis has proven difficult, as neurogenic phenotypes, independent

69 but acquiring similar evidence in humans has proven difficult.

70 nt molecular advances into clinical practice proves difficult.

71 ase caused by hepatitis C virus infection is proving difficult, despite the availability of curative

72 The approach we describe should prove directly translatable to other GPCRs, providing a

73 rect bladder instillation of antibiotics has proved disappointing in treating UTI, likely due to the

74 No therapeutics have yet been proven effective for the treatment of mild-illness cause

75 e of treatment response in sRCCs, although a proven effective systemic agent remains elusive.

76 No proven effective therapies for this virus currently exis

77 While the majority of these measures are proving effective, they have a high social and economic

78 The compounds discussed in this review have proven efficacious in human cell lines, patient-derived

79 Despite proven efficacy of pharmacotherapies targeting primarily

80 of green-type Rca found in higher plants has proved elusive, in part because until recently higher-pl

81 re funneled into polyketide biosynthesis has proven elusive.

82 This effect proves essential to the formation, shape, and speed of l

83 onal (1)H-(15)N correlation experiments have proven exceedingly difficult to implement on mAbs, and a

84 bservation is the first unique evidence that proves experimentally the existence of diatropic current

85 tery using the radiocarbon dating method has proven extremely challenging owing to the limited surviv

86 ting phases in complex quantum materials has proven extremely challenging.

87 es would be responsible for a given disorder proved false.

88 re confined to their localized areas, rarely prove fatal for device performance, and are largely not

89 for future engineering applications and (5) proven feasibility and biocompatibility in an animal mod

90 etween Berry phase and Hannay angle has been proven for a large set of quadratic Hamiltonians, such c

91 gistic use of the techniques discussed could prove fruitful in generating a detailed map of cAMP sign

92 dance monitoring on therapy in patients with proven gastroesophageal reflux disease [GERD]), to docum

93 third handheld spectrometer, representing a proven good performance for fruit quality analysis, was

94 ust organic semiconductor photocatalyst with proven H(2) evolution ability.

95 This was an analysis from the PROVE-HF study (Prospective Study of Biomarkers, Symptom

96 rotein G, so called REX and ARS ligands with proved high affinity and selectivity to the human interl

97 Oral miltefosine in monotherapy has proven high efficacy in CL caused by L. braziliensis wit

98 e 3D created volumes, a method with previous proven high precision and accuracy.

99 /2 dimer-deficient mice, a subset of tissues proved highly sensitive to loss of cooperativity.

100 We included patients with neuroimaging-proven ICH, available DNA and 6-month follow-up in an ob

101 Terminal uranium nitrides have so far proven impossible to isolate by photolysis of azides.

102 ition of monomer 4 and P for Al(3+) was also proved in presence of Na(2)EDTA by both UV-Vis and fluor

103 ce of EPPGE over mercury electrodes has been proved in terms of sensitivity and imperative analytical

104 The assay was proven in plasma from CRC patients and healthy donors, a

105 vity of ivermectin has not been consistently proven in vivo.

106 Previous studies have proved inconsistent across several behavioral endpoints

107 However, FTIs proved ineffective against KRAS-driven tumors.

108 Five of 6 cases (83%) had culture-proven infectious endophthalmitis (2 Candida glabrata, 2

109 ormation of an alpha-methylene-gamma-lactone proved instrumental, which had not found application in

110 SMA11) PET/MRI for initial staging of biopsy-proven intermediate- or high-risk PC, and 57 patients (m

111 er the last 8,000 to 12,000 years, they have proved invaluable for creating precise and accurate time

112 Animal models have proved invaluable in revealing a wealth of diverse cellu

113 To prove it, we first performed a bioinformatics analysis o

114 using patient-specific parameters; then, we prove its applicability on population data, without the

115 Over the past 10 years, this distinction has proven its diagnostic value as well as its important pro

116 cancer targeted sequencing, and has already proven its use in a research laboratory environment.

117 e frequently found at buccal sites (51%) and proved less prevalent at mesio-lingual sites (16.7%).

118 pharmacological approaches to treatment have proven less effective than previously thought, whereas s

119 Acetaminophen (APAP) is a proven lethal oral toxicant in reptiles but the physiolo

120 Forty-four patients (with pathologically proven lymphoma disease) underwent staging (18)F-FDG PET

121 ior left thigh lesion confirmed to be biopsy-proven melanoma.

122 monstrate that the learned lick behavior may prove more pertinent in investigating brain driven pain

123 The latter approach proved more robust in our hands and yielded a thickness

124 mmunities in intensive-agricultural habitats proved more susceptible to changes in climate, with hott

125 icrobiome profiles of 171 Asians with biopsy-proven NAFLD and 31 non-NAFLD controls are analyzed usin

126 1557 multiethnic adult patients with biopsy-proven NAFLD enrolled into 4 different studies conducted

127 ncing was performed in a cohort of 83 biopsy-proven NAFLD patients and 13 patients with non-invasivel

128 Escherichia coli LPS in patients with biopsy-proven NAFLD, 25 simple steatosis (nonalcoholic fatty li

129 Our aims were to determine whether biopsy-proven NASH impacts clinical outcomes in CHB patients an

130 y of 180 severely obese patients with biopsy-proven NASH, defined by the NASH clinical research netwo

131 urther supplementation and modification will prove necessary.

132 ng the spine spike, and ultrastructural data prove NMDAR presence within the GABAergic presynapse.

133 ifferent superhyphenations were successfully proven: NP-HPLC-UV/vis/FLD-bioassay-RP-HPLC-UV/vis-ESI(-

134 We thus propose that paraspeckles may prove of use as mechanosensors in cancer mechanobiology.

135 9 that led to institutional or legal actions proving or supporting guilt.

136 5, bearing a para-benzyladenine substituent, proved particularly potent against USA300 and additional

137 mean age, 63 years; range, 18-95 years) with proven PE.

138 steroids and symptomatic management, without proven positive effects on long-term outcomes.

139 a similar analysis of yeast colonies has not proved possible.

140 In this review, we discuss tools that have proven powerful in the investigation of nucleosome and c

141 detection of human MutY (MUTYH) variants may prove predictive of early-onset colorectal cancer known

142 here is no change in the classifications of "proven," "probable," and "possible" IFD, although the de

143 l between 21 February and 16 April 2020 with proven/probable COVID-19, 45 (96%) of whom fully recover

144 exibility of the linking function, which has proved prohibitive for understanding the complex dynamic

145 odifications and combinations of methods may prove promising and need to be explored.

146 eneva, and Valencia) assessing the challenge-proven rate of coexistent peanut, tree nut, and/or sesam

147 ents (46% men) with single, sporadic, biopsy-proven RCC (median size +/- standard deviation, 2.8 cm +

148 time between ctHPVDNA positivity and biopsy-proven recurrence was 3.9 months (range, 0.37-12.9 month

149 ractice, and to consider extending access to proven rehabilitative therapies during the first year po

150 c allograft recipients at the time of biopsy-proven rejection.

151 This method has also proved reliable for detecting calcium as well as several

152 wild or captive) rely on social learning has proved remarkably challenging.

153 riming activity, with the ADDD+DADD fraction proving remarkably effective.

154 Allergen immunotherapy is a proven, safe treatment for respiratory allergies.

155 Hydroxyurea has proven safety, feasibility, and efficacy in children wit

156 Overall, the developed protocols prove SB as highly sensitive, selective and recyclable '

157 reater number of crops include the dearth of proven selectable marker gene-selection combinations and

158 s (NEC) (Bell stage II or more), and culture-proven sepsis.

159 ods development to improve implementation of proven services to reduce disparities in preventable con

160 scribes autopsy findings in 10 patients with proven severe acute respiratory syndrome coronavirus 2 (

161 tion, bioengineering, and gene transfer have proved successful in rescuing salivary gland function in

162 re desirable alternatives, but none have yet proven successful despite their ability to opsonize eryt

163 ases and quarantining those in contact, have proven successful in bringing the epidemic under control

164 mophores using mutation strategies that have proven successful in native cupredoxins.

165 development of celiac disease have not been proven successful in randomized trials, but the quantity

166 The obtained results proved sufficient repeatability (RSD = 2.4%), reproducib

167 nsals, and the bacterial RNA polymerase is a proven target for antibiotics.

168 th all simulation models, our study does not prove that a ban of iTFA will prevent IHD, rather, it pr

169 We prove that a local conformational change spreads omnidir

170 To prove that a MAB can be more sensitive and have a better

171 We prove that all properly two-colored, undirected, regular

172 We mathematically prove that any embedding (that uses dot products to meas

173 Contrastingly, we prove that incorrectly identifying imported cases as loc

174 We prove that light driven perturbations of cell membrane p

175 a Co-doped iron arsenide superconductor and prove that the application of the algorithm allows for t

176 We prove that the common believe that great tsunamis do not

177 We prove that the local unitaries of an HRE quantum memory

178 n-feedback-controlled power application, and prove that the output power can be effectively adjusted

179 We prove that the trend correlation based screening approac

180 ture, while predictive models were tested to prove that VOCs can be accurately predicted using genomi

181 f natural allelic variation of the ENO locus proved that a cis-regulatory mutation in the promoter of

182 DV-1) has been increasing, ever since it was proved that BoDV-1 can cause human infections.

183 ntiglycolipid antibody-mediated neuropathies proved that some of these antibodies are directly involv

184 It was proved that the 5 mum-thick membranes are stable at late

185 th controlled and online NMR experiments, we proved that the reaction path is following the organocat

186 Detailed analyses of a few selected muteins proved that the screening method is efficient and accura

187 Meanwhile, it is also proven that a timely and broad application of testing le

188 It has been proven that at increased temperature, sterols can underg

189 Although recent studies have proven that CE between two solids is primarily due to el

190 Here we have proven that newly synthesized chiral naphthalene diimide

191 r, glycidyl ester and trace metals) analyses proven that refined PPMO is safe to be consumed.

192 The present MEDT study proves that analysis of the electrophilicity and nucleop

193 The first total synthesis now proves that the structure of this compound had originall

194 d by electrochemical impedance spectroscopy, proving that the new system can be applied to evaluate t

195 terpenes, esters and alcohols content, thus proving that the yeast-inoculating form may typify the o

196 ted by exactly four surface Fermi arcs, thus proving that they carry the maximal Chern number magnitu

197 The results prove the ability of the ML-based model to correctly cla

198 In order to prove the applicability of the method to different chemi

199 These results prove the potential of our method to develop a noninvasi

200 We prove the stability properties for non-complete entangle

201 glucosamine tetrasaccharide was assembled to prove the utility of MPF.

202 SAED ultimately proved the complete transformation of face-centered cubi

203 Those pioneering studies proved the feasibility of retrosynthetically guided acce

204 genomic, transcriptomic, and proteomic data proved the presence of a reduced form of the translocon

205 This signature proves the existence of multiple pulses (including a sol

206 tion of paramagnetic chlorine atoms for IAEs proves the magnetic nature of quasi-atomic IAEs through

207 ntation into a normal microenvironment, thus proving the active role of the BM stroma.

208 [B(2)C(4)H(4)](2-) diboratabenzenes, thereby proving the higher persistence of the aromaticity of the

209 equencing technologies, these platforms have proven their ability to resolve some of the most challen

210 hich can be obtained from fruit wastes, have proven their potential as plant immune-system elicitors.

211 Lithium-ion batteries have proven themselves to be indispensable among modern day s

212 rocess is a means to enable oral delivery of proven therapeutic antibodies as well as novel antibodie

213 n of orthoretroviruses such as HIV-1 and are proven therapeutic targets.

214 Studies aiming to prove this concept by immunizing experimental animals wi

215 y fate of a horizontally transferred gene to prove this theory.

216 The SEVERE index may prove to be a useful instrument in identifying patients

217 This dataset should prove to be a valuable resource leading to the identific

218 bition of in vitro platelet phagocytosis may prove to be a valuable tool for determining which erythr

219 st efficient diether and amino ether ligands prove to be foreseeable by modeling the reaction with th

220 nts, and consistent secondary prevention can prove to be key elements to improving post-discharge mor

221 However, salivaricins may also prove to be of great value in the development of new and

222 d defective GaS(0.87) and stoichiometric GaS prove to be promising platforms for study of novel pheno

223 ity-supported neurotechnology platforms will prove to be transformational in accelerating ideas from

224 Among them, OP-5244 (35) proved to be a highly potent and orally bioavailable CD7

225 EVM proved to be a promising tool for targeted EMB because o

226 g those, chitosan nanoparticles (ChNPs) have proved to be a quite popular choice.

227 mical staining especially in corpus biopsies proved to be a risk factor for failure of first-line tri

228 HARDI-ZOOMit protocol proved to be a sensitive and practical tool for clinical

229 3D printing proved to be a suitable and fast method for replicating

230 nd that, when studied in human cancer cells, proved to be able to stabilize both G-quadruplexes and R

231 In contrast, (+)2,3,5,6TMP-TQS proved to be an alpha7 PAM.

232 ide type mast cell stabilizer, MCS-01, which proved to be an effective mast cell degranulation inhibi

233 the present work, for the first time, bR is proved to be an n-type semiconductor with an indirect el

234 roxytryptamine (5-HT; Serotonin) release has proved to be challenging.

235 s high-performance adsorbents, were not only proved to be economically promising, due to recycling of

236 Although immunotherapy has proved to be effective in a variety of cancer subtypes,

237 The reaction proved to be general in scope and proceeds through a tri

238 uced joint instability, TIMP3 overexpression proved to be less protective in cartilage destruction th

239 carrots with the highest concentrations also proved to be more bioaccessible (p < 0.05).

240 noninvasive and low-tech procedures, and it proved to be predictive of postoperative DED symptoms on

241 Therefore, the proposed model proved to be promising and reliable for verifying authen

242 antitation of SARS-CoV-2-specific antibodies proved to be robust and can be conducted in many laborat

243 limination of a sulfur mustard simulant, has proved to be significantly more efficient than TBP and E

244 correction models, ORM-SSB correction model proved to be the best to eliminate the matrix effects an

245 soaking rice with extra water before cooking proved to be the method that generates the greatest redu

246 Gallic acid proved to be the most bioaccessible PC (6359 mug/g).

247 e pretreatment (raw, salting or dehydration) proved to have a low influence.

248 oly(tetrafluoroethylene) molecular chain are proved to have a much stronger EW ability than the satur

249 years, octacyanidometallate-based materials proved to offer varied and remarkable functionalities, b

250 However, the NPA method proved to take more time than the routine method for NGI

251 Overall, 25 (72%) of 35 regions of interest proved to visualize a tumor signal according to standard

252 LP-1R) imaging with radiolabeled exendin has proven to be a powerful tool to quantify beta-cell mass

253 The propargyl electrophile has proven to be a versatile reactant when coupled with pall

254 but the elucidation of its genetic basis has proven to be a very challenging endeavor.

255 Some of the obtained compounds were proven to be active as inhibitors of PDE1 isoforms, with

256 Our workflow has been proven to be an effective alternative for current nanopr

257 ponses, and blockade of this interaction has proven to be an effective immunotherapy for several diff

258 This approach has proven to be an efficient and cost-effective way to iden

259 However, near-infrared photodetection has proven to be challenging and, to date, the true potentia

260 e using top-down lithographic approaches has proven to be challenging due to poor structural control

261 rs that undergo such flexible adaptation has proven to be difficult to establish using simplified mod

262 uman brain tissue samples, a source that has proven to be difficult to work with image-based spatial

263 Fluorescent staining with Nile red dye has proven to be effective at distinguishing microplastics f

264 une checkpoint inhibitors (ICIs), which have proven to be effective cancer therapies in many malignan

265 e in treating mania, few antipsychotics have proven to be effective in bipolar depression.

266 diabetic retinopathy and its modulation has proven to be effective in curbing pathologic angiogenesi

267 Although the PubMLST scheme has proven to be highly discriminatory and informative, the

268 eduction of 3-substituted cyclobutanones was proven to be highly selective for the formation of cis a

269 d the energy expenditure per peptide bond is proven to be independent of the stability of the interme

270 differentiates the metastatic phenotype has proven to be more elusive.

271 gineered mouse models (GEMMs) of cancer have proven to be of great value for basic and translational

272 erving geometric algorithms, which have been proven to be superior to the conventional algorithms bas

273 ence of transient provoking risk factors has proven to be the most important determinant of VTE recur

274 animal cells, particularly in teleosts, has proven to be very efficient with regards to mutation rat

275 m 1 to 50 nM, the AuNPs modified Au chip was proven to clearly be a better analytical tool.

276 cally relevant therapeutic modality that has proven to compensate for the reduced therapeutic efficac

277 Antiarrhythmic drugs have not proven to significantly improve overall survival after o

278 leased in the CASP13 experiment, AWSEM-Suite proves to be a reasonably accurate algorithm for free mo

279 f the approach linked with the current stage proves to be unfeasible, and the "treatment stage altern

280 Overall, the phyllosphere is proving to be both an important microbial habitat and a

281 anagement tools, electrochemical sensors are proving to be reliable solutions; specifically, impedime

282 CRISPR-based diagnostic approaches are proving to be useful as field-deployable solutions.

283 helial cells for vascular normalization, are proving to effectively deliver therapeutics to tumours.

284 Cyclic coordination clusters (CCCs) are proving to provide an extra dimension in terms of exotic

285 rome coronavirus 2, has spread globally, and proven treatments are limited.

286 , which is elevated early in disease and may prove useful as a first round screen to identify individ

287 Rayleigh-wave OCE may prove useful for clinical diagnosis, refractive surgerie

288 for identifying symptom-specific targets may prove useful for other disorders and facilitate personal

289 ee-standing monolayer amorphous carbon could prove useful for permeation and diffusion barriers in ap

290 y small molecules with properties that might prove useful for the treatment of some neuromuscular dis

291 This work could prove useful in making superhard materials and engineeri

292 rting sex differences in risk taking and may prove useful in understanding sex differences in the pre

293 ignment of amino acid sequences, which could prove useful in various contexts - in particular the ana

294 oughput screening data, scaffold graphs have proven useful for the navigation and analysis of chemica

295 ses (AAVs) are dependoparvoviruses that have proven useful for therapeutic gene transfer; however, ou

296 It has also proven useful in monitoring the response to treatment an

297 Regulating and encouraging the use of proven vehicle safety technologies in LMICs would have l

298 d-related defense genes, which have recently proven vital in plant resistance to necrotrophic fungal

299 Tumor recurrence was defined as biopsy-proven vital tumor at the initial tumor site.

300 The nomogram proved well calibrated and had good discriminative abili