ライフサイエンスコーパス: prove to be

1 ith germline BRCA1 or BRACA2 mutations might prove to be a harbinger of advancement in targeted thera

2 g to increase serotonergic signalling, might prove to be a more coherent approach to the development

3 Furthermore, this approach may prove to be a more general mechanism for inhibiting prot

4 The SEVERE index may prove to be a useful instrument in identifying patients

5 tudinal studies, the choriocapillaris FD may prove to be a useful parameter for evaluating the functi

6 This dataset should prove to be a valuable resource leading to the identific

7 bition of in vitro platelet phagocytosis may prove to be a valuable tool for determining which erythr

8 Yet it has proved to be a challenging task.

9 ence after negative MRDTI was low, and MRDTI proved to be a feasible and reproducible diagnostic test

10 Among them, OP-5244 (35) proved to be a highly potent and orally bioavailable CD7

11 Cholesterol proved to be a key molecule for the function of synapses

12 ment learning from imperfect data, which has proved to be a major obstacle to its application to phys

13 D138(+) plasma cell densities simultaneously proved to be a meaningful new measure of inflammation.

14 e well-known metabolite norfluoxetine (NFLX) proved to be a minor TP in photolysis (<=2% of degraded

15 Vitiligo has thus proved to be a particularly tractable model for investig

16 croplastic particles were for the first time proved to be a persistent source releasing bisphenol A i

17 Coffee flowers proved to be a potential raw material for making tea-lik

18 Mass spectrometry (MS) has been proved to be a powerful technique in comprehensive chara

19 Furthermore, it proved to be a promising material for potential applicat

20 EVM proved to be a promising tool for targeted EMB because o

21 g those, chitosan nanoparticles (ChNPs) have proved to be a quite popular choice.

22 Endogenous retroviruses have proved to be a reliable genetic marker for studying the

23 mical staining especially in corpus biopsies proved to be a risk factor for failure of first-line tri

24 This proved to be a robust method to CIR confirmation in a bi

25 HARDI-ZOOMit protocol proved to be a sensitive and practical tool for clinical

26 repare nanocrystals of Pb(3)S(2)Cl(2), which proved to be a structural analogue of the recently repor

27 3D printing proved to be a suitable and fast method for replicating

28 likely that this exothermic trapping process proved to be a tipping point for an already turbulent mi

29 Citizen science has proved to be a unique and effective tool in helping scie

30 oping, especially on the lead site, has been proved to be a useful strategy to obtain the desired fil

31 The proposed method proved to be a useful tool for quality control in the ri

32 The electroretinogram (ERG) has proved to be a valuable tool to investigate psychiatric

33 Gelatin fining proved to be a very effective treatment for astringency

34 Architected materials or metamaterials have proved to be a very effective way of making materials wi

35 Starvation resistance proved to be a weak predictor of functional ageing.

36 been used for this purpose, yet it has been proven to be a convenient and robust method to site-sele

37 Although none of these models has proven to be a fully faithful reproduction of the human

38 ogical assays to detect antibodies have been proven to be a great complement to the standard method o

39 s or NGP within polymer material science has proven to be a highly attractive strategy.

40 an easily quantifiable visual trait that has proven to be a highly tractable system for genetic analy

41 Optical imaging of the OB has proven to be a key tool in elucidating the spatial odor

42 enic RAS using small-molecule approaches has proven to be a major challenge.

43 Regulatory T cells (Treg) have proven to be a powerful immunologic force in nearly ever

44 Mass spectrometry has been proven to be a powerful technique for protein sequencing

45 Inertial microfluidics has been proven to be a powerful tool for high-throughput, size-b

46 nd small molecules, direct laser cooling has proven to be a powerful tool for quantum science in the

47 LP-1R) imaging with radiolabeled exendin has proven to be a powerful tool to quantify beta-cell mass

48 andard to determine conscious state, EEG has proven to be a promising complementary tool to monitor t

49 Single-serve machines have proven to be a rapid and convenient mechanism for prepar

50 oscope (Medtronic, Minneapolis, MN) has been proven to be a reliable alternative for in-hospital airw

51 Given that PDE10A has been proven to be a safe drug target, PDE10A inhibition may r

52 In this sense, saliva has proven to be a strategic biofluid, owing not only to its

53 70s, the rechargeable alkali-ion battery has proven to be a truly transformative technology, providin

54 domestic ferret (Mustela putorius furo) has proven to be a useful species for modeling human genetic

55 Moreover, it has proven to be a useful tool to construct organic luminoph

56 -Trifluorodiazoethane (CF(3)CHN(2)) has been proven to be a valuable reagent for the rapid synthesis

57 vely switch on such pathways upon demand has proven to be a valuable tool in biological systems.

58 sualization of the transcriptome in situ has proven to be a valuable tool in exploring single-cell RN

59 Aza-glycine has proven to be a valuable tool in the design of triple-hel

60 Dipolar EPR spectroscopy has proven to be a valuable tool to determine coarse-grained

61 The propargyl electrophile has proven to be a versatile reactant when coupled with pall

62 but the elucidation of its genetic basis has proven to be a very challenging endeavor.

63 PAX8 has proven to be a very useful diagnostic marker in a select

64 ration rate compared to CP patients, and has proven to be a viable therapy for the treatment of indiv

65 leased in the CASP13 experiment, AWSEM-Suite proves to be a reasonably accurate algorithm for free mo

66 s, however our data clearly shown that AURKB proves to be a singular finding and potential prognostic

67 the available small molecule toolbox and is proving to be a viable drug discovery strategy, as evide

68 nd that, when studied in human cancer cells, proved to be able to stabilize both G-quadruplexes and R

69 Community-based football proved to be acceptable, even when club membership was n

70 complexes with NHC trans to the active site proved to be active electrocatalysts capable of selectiv

71 Some of the obtained compounds were proven to be active as inhibitors of PDE1 isoforms, with

72 The diafiltration/ultrafiltration process proved to be adequate and easy to handle to scale up the

73 m layered two-dimensional crystallites could prove to be advantageous.

74 illions of years of evolution and frequently prove to be among the most sophisticated.

75 excitability in a focal, modular manner may prove to be an effective therapeutic for treatment-resis

76 In contrast, (+)2,3,5,6TMP-TQS proved to be an alpha7 PAM.

77 cation in clinical diagnostics and agri-food proved to be an attractive strategy, complementary to tr

78 ide type mast cell stabilizer, MCS-01, which proved to be an effective mast cell degranulation inhibi

79 DHPO has proved to be an effective trap for such highly reactive

80 in presence of a pancreatic lipase inhibitor proved to be an efficient way to widen the scope of the

81 The FDA proved to be an efficient, reasonable, and communicative

82 Human beta-cardiac myosin has proved to be an excellent target for small-molecule ther

83 ion of such systems, computer simulation has proved to be an invaluable tool, and many researchers in

84 the present work, for the first time, bR is proved to be an n-type semiconductor with an indirect el

85 Our workflow has been proven to be an effective alternative for current nanopr

86 The strawberry pulp has proven to be an effective alternative to increase the co

87 ponses, and blockade of this interaction has proven to be an effective immunotherapy for several diff

88 horus-impregnated carbon nanofibers has been proven to be an effective method to minimize the side re

89 psulation of shrimp oil in nanoliposomes was proven to be an effective method to prevent oxidation of

90 nd bulk defects of perovskite films has been proven to be an effective way to minimize nonradiative r

91 This approach has proven to be an efficient and cost-effective way to iden

92 Genomic selection (GS) has proven to be an efficient tool for predicting crop-rank

93 It has been proven to be an etiological factor in various infections

94 -phase, double resonance IR spectroscopy has proven to be an excellent approach to obtain structural

95 Kinetic resolution using biocatalysis has proven to be an excellent complementary technique to tra

96 Fungi have proven to be an excellent, but underexplored source for

97 roved optical and electrical properties, was proven to be an ideal candidate material used as transpa

98 eams merged with theoretical approaches have proven to be an ideal tool to elucidate intrinsic struct

99 Even though genetic predisposition has proven to be an important element in Parkinson's disease

100 MPORTANCE High-temperature environments have proven to be an important source for the discovery of ne

101 The least-cost path problem has proven to be an instrumental analytical tool in this sen

102 LC-MS/MS proves to be an alternative for detection of Hcrt1 for d

103 D(4)-1alpha proves to be an extraordinarily active and efficient cat

104 SPIM-FRAP proves to be an order of magnitude faster than fluoresce

105 The rs352140-TT in the TLR9 gene proved to be associated with lower risk to severe period

106 AC proved to be better in reducing C(free) PAHs than biocha

107 ice with severed and anastomosed C7 nerve is proven to be both safe and effective.

108 Overall, the phyllosphere is proving to be both an important microbial habitat and a

109 AI has proved to be capable of completing a spectrum of mundane

110 r global health initiatives, this investment proved to be catalytic, and indeed highlights how foreig

111 Small RNA-Seq (sRNA-Seq) data analysis proved to be challenging due to non-unique genomic origi

112 roxytryptamine (5-HT; Serotonin) release has proved to be challenging.

113 However, near-infrared photodetection has proven to be challenging and, to date, the true potentia

114 he synthesis of sodium diazeniumdiolates has proven to be challenging due to hazardous reaction condi

115 e using top-down lithographic approaches has proven to be challenging due to poor structural control

116 itors devoid of type III kinase activity has proven to be challenging.

117 However, aneurysm detection proves to be challenging and time-consuming.

118 regulation of HIF-1alpha have not currently proven to be clinically useful.

119 tivation and gluco-metabolic homeostasis has proven to be complex and potentially inconsistent across

120 the structure specificity of lipid analysis proves to be critical for studying the biological functi

121 tness landscapes produce rich behaviors, and prove to be crucial for ecological and evolutionarily st

122 Statins have been proven to be cytotoxic to human cholangiocarcinoma cells

123 c autoimmune diseases; however, TNFalpha has proven to be difficult to drug with small molecules.

124 rs that undergo such flexible adaptation has proven to be difficult to establish using simplified mod

125 uman brain tissue samples, a source that has proven to be difficult to work with image-based spatial

126 ets have been widely utilized, their use has proven to be difficult, and methods to clean and filter

127 alide perovskite semiconductors has thus far proven to be difficult.

128 s high-performance adsorbents, were not only proved to be economically promising, due to recycling of

129 tes the metastatic potential of PDAC and may prove to be effective for treating advanced disease.

130 In conclusion, the Ca37 monoclonal antibody proved to be effective against C. albicans, both in vitr

131 Although immunotherapy has proved to be effective in a variety of cancer subtypes,

132 ed recombinant monoclonal anti-IgE antibody, proved to be effective in patients with chronic spontane

133 act obtained through eco-friendly techniques proved to be effective to reduce the formation of hydrox

134 Fine mapping proved to be effective to refine the previous GRS.

135 R) T-cell therapy of B-cell malignancies has proved to be effective.

136 ergic agonists salbutamol and ephedrine have proven to be effective as therapies for human disorders

137 In recent years, deep neural networks have proven to be effective at capturing the complex patterns

138 Fluorescent staining with Nile red dye has proven to be effective at distinguishing microplastics f

139 une checkpoint inhibitors (ICIs), which have proven to be effective cancer therapies in many malignan

140 Though small molecule-based additives have proven to be effective defect passivating agents, their

141 External ligands have proven to be effective for C(sp(3) )-H fluorination dire

142 ORTANCE Adeno-associated viruses (AAVs) have proven to be effective gene transfer vectors.

143 e in treating mania, few antipsychotics have proven to be effective in bipolar depression.

144 diabetic retinopathy and its modulation has proven to be effective in curbing pathologic angiogenesi

145 ing Tmprss6 messenger RNA by Tmprss6-ASO was proven to be effective in improving IE and splenomegaly

146 iologic studies, these risk factors have not proven to be effective in predicting an individual's ris

147 Thus far, no therapy has proven to be effective in the adjuvant setting.

148 erimental design in the optimization process proves to be effective with minimum experiments and cost

149 ctured forms of stoichiometric In(2)O(3) are proving to be efficacious catalysts for the gas-phase hy

150 This food coating proved to be efficient for the prolongation of shelf lif

151 arge product in Li-O(2) batteries), LiOH has proved to be electrochemically active as an alternative

152 he inactivation mechanism of 1, however, has proved to be elusive.

153 information on the identity of analytes and proved to be essential in the event of unresolved peaks

154 xically, these response biomarkers have been proven to be essential even in the presence of data demo

155 F signature sequence (e.g., TTVGYG) has been proven to be essential for this allosteric coupling.

156 preserving the encoded information(3-7) has proved to be experimentally challenging, and the only re

157 Notably, the cages formed by Ico8 proved to be extremely stable toward thermal and chemica

158 The conversion of conformers was proven to be facilitated by the presence of hydrogen-bon

159 orporeal chloride removal by electrodialysis proved to be feasible, safe, and effective.

160 st efficient diether and amino ether ligands prove to be foreseeable by modeling the reaction with th

161 In addition, the released proteins were proven to be functional in vitro.

162 , inducible site-specific endonucleases have proven to be fundamental tools.

163 The reaction proved to be general in scope and proceeds through a tri

164 This strategy proved to be general in various alkene silylation reacti

165 rature under an air atmosphere, the protocol proved to be general, and a variety of aryl O-glycosides

166 The reaction has proven to be general, as R(3) PF(2) , R(2) PF(3) , and R

167 If this result proves to be general, it would provide a powerful new to

168 four real datasets, MIPUP's reconstructions proved to be generally more faithful than those of LICHe

169 which atom transfer reactions are rare, also proved to be good substrates for this phosphine-/copper-

170 psies from patients, that were serologically proven to be HCV positive, were included in the current

171 d-derived NK (PB-NK) cells, hnCD16-iNK cells proved to be highly resistant to activation-induced clea

172 Overall, the image analysis software proved to be highly sensitive and can be utilized by lab

173 Both aiHp and resistance to clarithromycin proved to be highly significant (p<=0.001) and independe

174 The biosensor proved to be highly specific and sensitive, achieving a

175 iving cells with high spatial resolution has proven to be highly challenging.

176 Although the PubMLST scheme has proven to be highly discriminatory and informative, the

177 his novel method is also fully automated and proven to be highly robust for routine bioanalysis in dr

178 eduction of 3-substituted cyclobutanones was proven to be highly selective for the formation of cis a

179 Digital PCR (dPCR) technology has been proven to be highly sensitive and accurate in detecting

180 with a synergistic effect is attractive but proves to be highly challenging.

181 ctures, and it is those Review articles that proved to be his most cited publications.

182 This reaction has been proven to be IgE-independent acute systemic anaphylaxis,

183 ic and fluorescence imaging modalities could prove to be important tools for monitoring the pancreas

184 C substrates, the corresponding D-box region proved to be important for their degradation despite poo

185 The simulated spectra proved to be in good agreement with the experiment.

186 Furthermore, the diastereomer separation proved to be independent of alkali salts or other metal

187 d the energy expenditure per peptide bond is proven to be independent of the stability of the interme

188 nsitivity, qPCR analysis of the eDNA samples proved to be ineffective.

189 n, and neighboring nodes in a graph has been proved to be informative in PPI prediction.

190 ing, assessing global molecular dynamics can prove to be inherently impractical.

191 ng, the use of electronic cigarettes has not proven to be innocuous.

192 for hosting multi-strain models, which have proven to be insightful in a variety of studies centered

193 Native mass spectrometry (MS) is proving to be invaluable for this purpose, enabling anal

194 et family proteins, VeA, VelB and VelC, were proved to be involved in the regulation of patulin biosy

195 nts, and consistent secondary prevention can prove to be key elements to improving post-discharge mor

196 An electron-deficient sulfone ligand proved to be key for the successful implementation of th

197 uced joint instability, TIMP3 overexpression proved to be less protective in cartilage destruction th

198 Purified HypX proved to be metal-free, which makes it a unique catalys

199 n is catalyzed by copper, and the conditions proved to be mild and were amenable to a variety of func

200 Indeed, ageing has proved to be modifiable; by intervening in biological sy

201 synthesize 2D MWW-type materials, which may prove to be more broadly applicable to other layered zeo

202 ls, while naive and less mature memory cells prove to be more resistant.

203 However, this last tool proved to be more accurate in the groups' formation.

204 carrots with the highest concentrations also proved to be more bioaccessible (p < 0.05).

205 selection of an organic phenoxazine PC that proved to be more effective in catalyzing C-N cross-coup

206 Direct extraction of faecal slurry was proved to be more reproducible than freeze-drying.

207 ectrophoresis (CE)-based hybridization assay proved to be more robust than reversed transcription pol

208 Overall, silicone rubber passive samplers proved to be more sensitive than sentinel organisms for

209 differentiates the metastatic phenotype has proven to be more elusive.

210 , the lower limb accelerometry-based metrics proved to be most informative.

211 ual and couple-based interventions have been proven to be most feasible, and the development and use

212 Among others, CaiT-D288A and -D288R proved to be mostly monomeric in detergent solution and

213 OTA has a chronic toxic effect and proved to be mutagenic, nephrotoxic, teratogenic, immuno

214 t for superiority was planned if rivaroxaban proved to be noninferior to enoxaparin.

215 to act as substrates for HIV-RT, while they proved to be nonsubstrates for DNA-polymerases alpha, be

216 However, salivaricins may also prove to be of great value in the development of new and

217 Knowledge of these parameters has been proven to be of great clinical significance for the diag

218 gineered mouse models (GEMMs) of cancer have proven to be of great value for basic and translational

219 ortant for innate immune defenses, which may prove to be one of the key mechanisms by which tobacco s

220 The bromodomain of ATAD2 has proved to be one of the least-tractable proteins within

221 Rare coding variants have been proven to be one of the significant factors contributing

222 HCN was proven to be oxidized by lattice oxygen of the catalyst

223 cluding the definition of an entropy metric, proved to be particularly relevant for Alzheimer's disea

224 radius space that contains few planets) have proved to be particularly valuable in this regard.

225 The dinaphthylcyclooctynes proved to be poorly reactive with azides, and the format

226 rapy, and, recently, immunotherapy, PDAC has proved to be poorly responsive to these treatments, with

227 de antigen delivered a vaccine modality that proved to be potent in activation of dendritic cells, in

228 ataset variability), PLS-DA and SIMCA models proved to be powerful tool with predict power higher tha

229 models derived from either UHPLC-MS or GC-MS proved to be powerful tools for discrimination of C. sil

230 Plasma levels of natriuretic peptides have proven to be powerful diagnostic and prognostic biomarke

231 noninvasive and low-tech procedures, and it proved to be predictive of postoperative DED symptoms on

232 d defective GaS(0.87) and stoichiometric GaS prove to be promising platforms for study of novel pheno

233 Therefore, the proposed model proved to be promising and reliable for verifying authen

234 In these experiments, the retention models proved to be quite accurate for both the (1)D and (2)D s

235 ver, the yields obtained from isolation have proven to be really low (<0.01%), greatly hindering the

236 the degradation of unsaturated TGs over time proved to be relatively reproducible in multiple individ

237 The approach proved to be reliable and revealed long-term maintenance

238 anagement tools, electrochemical sensors are proving to be reliable solutions; specifically, impedime

239 different brands and 128 different labels), proving to be reliable.

240 This procedure has proved to be remarkably effective in premature newborns,

241 Unlike neonatal pups, late gestation fetuses proved to be resistant to rhesus rotavirus (RRV) mediate

242 antitation of SARS-CoV-2-specific antibodies proved to be robust and can be conducted in many laborat

243 s therefore technically matured and has been proved to be safe.

244 repurposing of antibiotics that have already proven to be safe and effective for clinical use.

245 ptive transfer of virus-specific T cells has proven to be safe and effective for the treatment of man

246 This virus has proven to be safe and effective in adult gliomas.

247 lower limbs, endovascular embolisations have proven to be safe and effective; orthopaedic surgeons sh

248 n K antagonist oral anticoagulants have been proven to be safer and equally effective compared with w

249 limination of a sulfur mustard simulant, has proved to be significantly more efficient than TBP and E

250 the studied landraces and Andean accessions proved to be similar enough to be considered as genotype

251 The approach has proved to be simple, fast, robust, and convenient for im

252 of the SPA approach to assess solubility has proven to be simple, fast, and both solvent- and sample-

253 on-accepting ligands in these species, which proved to be small.

254 o major APOL1-second gene interactions, will prove to be stronger modifiers of the risk for nephropat

255 synaptic, subthreshold and spiking responses proves to be substantially more selective than for TRFs.

256 vely rapid genotyping by sequencing approach proved to be successful in delineating arapaima stocks.

257 The naturally abundant isotope (89)Y is proving to be suitable for nuclear magnetic resonance in

258 The autogenous soft tissue graft (CTG/FGG) proved to be superior in all comparisons for both outcom

259 treatment with CB-839 and riluzole treatment proved to be superior to single-agent treatment, restric

260 liquid chromatography, the MMLC protocol has proven to be superior in both retentive capabilities and

261 erving geometric algorithms, which have been proven to be superior to the conventional algorithms bas

262 using atomic force microscopy (AFM) has been proven to be technically challenging.

263 correction models, ORM-SSB correction model proved to be the best to eliminate the matrix effects an

264 In our hands, CXCR1 and CXCR2 agonists proved to be the major mediators of cancer-promoted NETo

265 soaking rice with extra water before cooking proved to be the method that generates the greatest redu

266 Gallic acid proved to be the most bioaccessible PC (6359 mug/g).

267 pression and interaction of TRPA1 with TRPV1 proved to be the most critical for differential sensitiz

268 ysical separation between nanoelectrodes are proved to be the most crucial factors in the enhancement

269 P453L proved to be the most deleterious substitution in struct

270 A C18 SPE cartridge paired with SPE GCB/PSA proved to be the most effective clean-up method and enab

271 Of all the factors, the collection season proved to be the most influential, followed by origin wi

272 A combination of the three techniques proved to be the most promising approach to establish cl

273 Bariatric surgery has proven to be the most effective treatment for controllin

274 The photogenerated holes were proven to be the most important active sites for directl

275 ence of transient provoking risk factors has proven to be the most important determinant of VTE recur

276 Targeting the IP in autoimmune diseases proved to be therapeutically effective in preclinical mo

277 was achieved using nitrogen plasma and this proved to be time-dependent.

278 ity-supported neurotechnology platforms will prove to be transformational in accelerating ideas from

279 These proved to be two stable rotamers, in which the carbonyl

280 MicroPET/single-photon emission CT have proven to be two of the most translational modalities fo

281 f the approach linked with the current stage proves to be unfeasible, and the "treatment stage altern

282 nce then, these organometallic entities have proven to be uniquely effective in catalyzing an assortm

283 The corresponding C2"-based analogues proved to be unstable.

284 Accordingly, A2764 may prove to be useful for the identification of TRESK curre

285 On the other hand, in vitro studies have proven to be useful for answering long-standing question

286 The latter have proven to be useful reagents in the reductive protonatio

287 Fluorescent amino acid analogs have proven to be useful tools for studying the dynamics of p

288 toactivation and photodissociation have long proven to be useful tools in tandem mass spectrometry, b

289 CRISPR-based diagnostic approaches are proving to be useful as field-deployable solutions.

290 human immunodeficiency virus (HIV) infection proved to be valuable tools to help uncover specific bio

291 example, similar single-cell approaches have proven to be valuable for elucidating the behavior and v

292 oxicity bioassays using artificial diet have proven to be valuable for monitoring resistance in many

293 The generated UV-radicals proved to be versatile and highly efficient polarizing a

294 Sequence-specific proteases have proven to be versatile building blocks for tools that re

295 A machine learning approach can prove to be very useful tool for hazard management and d

296 fering (137)Cs in the deposition product and proved to be very efficient (yields >70% for aqueous sam

297 mmercial oil, but its olfactory contribution proved to be very limited.

298 th Rare Earth Elements (REE) concentrations, proved to be very powerful predictors, for the tradition

299 animal cells, particularly in teleosts, has proven to be very efficient with regards to mutation rat

300 hons in a multicomponent reaction was herein proved to be viable and successful.