ライフサイエンスコーパス: provocative

1 impairment compared with sea level was very provocative.

2 We explore a novel and provocative activity of integrins in docking proteases t

3 sma calcitonin levels after stimulation with provocative agents.

4 These results provide provocative, although not conclusive, evidence for the i

5 te and colleagues provide an interesting and provocative analysis of a potential novel risk factor fo

6 This model provides a provocative and appealing target for future inhibitor de

7 One of the most provocative and exciting issues in cognitive science is

8 meeting review describes several of the most provocative and exciting talks from the symposium, revea

9 To consider and summarize provocative and important publications from 2009 and 201

10 an disease, and thus, these results are both provocative and important.

11 stogenesis in the anabolic regime suggests a provocative and paradoxical theme for the anabolic effec

12 ess of erythroblast enucleation has remained provocative and poorly understood.In this issue of Blood

13 Early results are both provocative and promising.

14 ineering, and mathematics (STEM) settings is provocative and raises questions about the extent to whi

15 statistically significant, these results are provocative and support the hypothesis that (CAG)n array

16 f apparently normal but irradiated cells are provocative and their transferability to human in vivo b

17 This question is a provocative and troubling issue currently facing society

18 n of these mutations or vice versa remains a provocative and unanswered question.

19 ervational variability, but the findings are provocative and warrant further evaluation.

20 n it was first published: clear, thoughtful, provocative, and usefully prescriptive in its call to ac

21 levels of IGF-1R binding on neutrophils, and provocative antitumor activity warrant additional studie

22 to pancreatic cancer remain one of the most provocative areas in the field of pancreatology.

23 nical trials are lacking, what has made this provocative argument even more convincing is the longsta

24 As astutely noted by the authors of this provocative article, it is time for evolutionary psychol

25 tic minireview series, the JBC presents five provocative articles on Enzyme Evolution.

26 omic data available in the decade since this provocative assertion, and use 'protein clusters' to eva

27 The provocative associations observed by Basu et al. between

28 daily rhythms of the fruit fly is especially provocative because the human ortholog lies in a candida

29 Tumor-infiltrating lymphocytes (TILs) are a provocative biomarker in melanoma, influencing diagnosis

30 Ten provocative bleeding studies were performed prospectivel

31 Here we provide direct evidence for this provocative but largely untested idea and demonstrate wh

32 nnatism at the heart of Cognitive Gadgets is provocative but premature, and is vitiated by dichotomou

33 uced mortality in patients<65 yrs of age are provocative but require further study to determine their

34 In the history of science, provocative but, at times, controversial ideas have been

35 Some of our ideas might be provocative, but we hope that the examples we provide wi

36 ross species, the CAPN1 variant represents a provocative candidate for the cause of SCA in the PRT an

37 e chief benefits obtained from studying this provocative case.

38 n the primary challenge model or just before provocative challenge in the secondary challenge model.

39 We show that PIT elements display provocative characteristics in certain biochemical assay

40 These results invite the provocative claim that neural responses to nonpolitical

41 In response to provocative comments by 2 European clinicians and scient

42 asymmetries in the stem and loop lengths and provocative composition differences between the loops.

43 , and 2 doubling dose or greater increase in provocative concentration of adenosine 5'-monophosphate

44 centration- and time-dependent change in the provocative concentration of allergen causing a 15% decr

45 subsequent beta2-agonist administration, the provocative concentration of bronchoconstrictive agents

46 with mild asthma were selected (for whom the provocative concentration of histamine aerosol causing a

47 ion correlated with baseline log PC(20) (the provocative concentration of methacholine causing a 20%

48 n forced expiratory volume in 1 s (FEV1) and provocative concentration of methacholine causing a 20%

49 associated with airway hyperresponsiveness (provocative concentration of methacholine causing a 20%

50 d not detect an effect of abatacept on FEV1, provocative concentration of methacholine sufficient to

51 ificity was 96% with a threshold PC(20) (the provocative concentration of methacholine that results i

52 Evolutionary materials synthesis is a provocative concept that has the potential for the disco

53 To explore this provocative concept, we derived androgen-sensitive and -

54 Provocative concepts and novel therapeutic avenues were

55 of a basophil and/or provide support for the provocative conclusion that a new previously overlooked

56 ctivation with compassion during emotionally provocative conditions.

57 al data derived from murine tumor models and provocative correlative data obtained by studying human

58 Such provocative data and the availability of newer 1alpha,25

59 Three types of provocative data have demonstrated bacterial presence fr

60 re transient and self-limiting, preliminary, provocative data have suggested the possibility of a mor

61 ourth Oxford Overview in September 2000, and provocative data on ovarian ablation were important feat

62 These provocative data provide preliminary evidence of clinica

63 Two studies provide compelling and provocative data questioning the relevance of these inte

64 his issue of the JCI, Fuentes et al. present provocative data regarding the use of direct megakaryocy

65 archaeological investigations because these provocative data sets offer critical insights into long-

66 In this issue of Neuron, present provocative data showing that microstimulation of the pr

67 These provocative data suggest that a CREB-dependent neuromech

68 These provocative data suggest that the indirect effects of in

69 prognostic markers, several studies reported provocative data using other markers such as Ki-67, p53,

70 The provocative data warrant confirmation in a RCT.

71 Provocative data were also presented suggesting that ret

72 of underlying pathobiologic mechanisms, the provocative destabilizing influences, the diagnostic and

73 Although GWAS results are highly provocative, direct analyses of the contribution of spec

74 in is diagnosed by the invasive procedure of provocative discography (PD).

75 The provocative discussion initiated by this team in this pu

76 a high PPV (0.81; 95% CI: 0.74, 0.87) for a provocative diskogram.

77 The primary outcome was change in the provocative dose of aspirin that caused a 2-point increa

78 The primary outcome was a change in the provocative dose of aspirin that would elicit an increas

79 sponsiveness was expressed as the cumulative provocative dose of carbachol, in breath units, that inc

80 mary outcome was doubling difference (DD) in provocative dose of mannitol required to decrease FEV(1)

81 ce in mannitol sensitivity, expressed as the provocative dose of mannitol required to reach a 15% dro

82 0% of functional vital capacity [FEF50], and provocative dose of methacholine causing a 15% decrease

83 [PD15]) and at age 7 years (FEV1, FEF50, and provocative dose of methacholine causing a 20% decrease

84 ld increased responsiveness to methacholine (provocative dose of methacholine producing a 15% decreas

85 The prevalence and mean provocative dose of oral aspirin (MPDA) triggering respi

86 The provocative dose to cause a 20% reduction (PD20) in FEV1

87 ac imaging, Holter-monitoring, and selective provocative drug testing with epinephrine or procainamid

88 These provocative eco-evolutionary contexts demand a theory of

89 Provocative electrophysiologic testing showed no differe

90 We observed provocative enhanced responsiveness of cultured human fi

91 ry based on their toxicologic properties and provocative epidemiologic reports.

92 Perhaps the most provocative evidence for an ancient ocean is a set of su

93 e, the labs of Knott and Theodorescu present provocative evidence suggesting that LOY in tumor cells

94 These results provide novel and provocative evidence that modulation of the gut microbio

95 In conclusion, these results provide provocative evidence that sildenafil is both a powerful

96 the affected replication domains, providing provocative evidence that they constitute biologically s

97 presented by ([this issue of Cell]) provides provocative evidence to support the theory that the high

98 ecently diagnosed patients with RA, but some provocative evidence was given that biopsychosocial vari

99 cted with Sin Nombre virus, which now allows provocative examination of the virus-host relationship.

100 Our study also presents a provocative example of where the brain selectively binds

101 In this article, we review some of the most provocative experimental results to have emerged from co

102 FLRT3 has a provocative expression pattern during somite development

103 rsion, identifying this toxin as a principal provocative factor for autophagy activation.

104 lease, identifying this toxin as a principal provocative factor for BBB activation.

105 However, the provocative failure of dopaminergic medications in addic

106 system, as well as highlights the recent and provocative finding that components of the GPCR traffick

107 The present studies reveal a provocative finding that recombinant MDA-7/IL-24 protein

108 that takes on additional importance with the provocative finding that short-term HSCs and downstream

109 These provocative findings advocate potential therapeutic appl

110 These provocative findings certainly question and undermine th

111 These provocative findings highlight mda-9/syntenin and its in

112 Although these provocative findings merit prospective validation, they

113 These provocative findings suggest that this combinatorial str

114 Epidemiologic insights reveal provocative findings with respect to risk factors and ra

115 The original provocative formulation of the 'geometric module' hypoth

116 orresponding to the presentation of the most provocative gambling stimuli.

117 This is provocative given reports of the possible role of inflam

118 These preclinical studies provide provocative hints into the direction MSC therapeutics ma

119 ose observed in DNA polymerases, and suggest provocative hypotheses for the more complex multisubunit

120 We delineate how this provocative hypothesis can be tested experimentally, and

121 ased sensitivity to 33-11/KH-4-43, raising a provocative hypothesis for the role of low E3 abundance

122 A provocative hypothesis links the disruption of the colla

123 scovery (epidemiologic) data have led to the provocative hypothesis that exercise treatment may impro

124 In this work, we put forward the provocative hypothesis that the active, ligand-bound RTK

125 nlargement (hyperplasia), and 2) suggest the provocative hypothesis that the continuous stimulation o

126 zed correspondence traces the emergence of a provocative hypothesis.

127 ative way of framing Huang & Bargh's (H&B's) provocative hypothesis.

128 resently described and named have led to the provocative idea that prokaryotes may not form species a

129 fundamental anticipatory processes and have provocative implications for many aspects of behavior an

130 Although highly provocative in its biological implications, if true, tec

131 of high levels of BPntase in the kidney are provocative in light of the roles of bisphosphorylated n

132 Provocative information suggests that infection with Hel

133 This study generates provocative insights for ongoing pre-clinical and clinic

134 nsplant have been actively investigated, and provocative insights into mucosal immunity and the enter

135 implicit solvent treatment suggests several provocative insights into the dynamics of the two subtyp

136 New and provocative insights into the relationships between iron

137 Recent advances provide provocative insights into these cell-biological and mole

138 Taken together, these studies offer provocative insights pertaining to the structural basis

139 Electric testing of the Riata lead with provocative isometric muscle contraction was performed a

140 While provocative, it is too soon to conclude that antioxidant

141 ng a polarizing political debate filled with provocative language but not during a neutrally worded n

142 Provocative leads of the definitive trials include the p

143 In a different light: In a provocative look at nanoscience, Nobel Laureate Roald Ho

144 loading has been suggested as an alternative provocative maneuver, but the hemodynamic changes induce

145 rdiac function, and hemodynamic responses to provocative maneuvers among patients with group 1 PH bas

146 hemodynamic profiles in response to various provocative maneuvers are definable with noninvasive, co

147 The provocative maneuvers included incremental isoproterenol

148 Those who underwent non-PV trigger provocative maneuvers or had spontaneous non-PV trigger

149 Provocative maneuvers, including postural changes, subli

150 degrees to 25 degrees, both with and without provocative maneuvers.

151 inct hemodynamic profiles are definable with provocative maneuvers.

152 y, after AF cardioversion, or after standard provocative maneuvers.

153 We organize this review in a somewhat provocative manner, with each section focusing on an imp

154 gorated the size control field and suggested provocative mechanisms for the distinct functions of set

155 These cells offer a provocative method to regenerate the damaged myocardium.

156 cellulase/hemicellulase complex, presents a provocative model for analyzing how structural and mutat

157 This compelling and provocative model links IkappaBalpha to the activity of

158 In a provocative model, catalytic-domain pairing was hypothes

159 studies of other AS enzymes, have engendered provocative molecular models to explain how this enzyme

160 ompanying study by Schootman et al. presents provocative new data on the apparently significant role

161 Provocative new data suggest that FLI1 shows monoallelic

162 issue of Blood, Richter and colleagues share provocative new data taking steps toward accomplishing t

163 hmer et al. (Cell 2019;176:113-126) presents provocative new evidence that extracellular vesicles/exo

164 These provocative new findings provide evidence for how activa

165 ers and the activation of microglia, raising provocative new questions about the safety profile of re

166 ew look at enhancer function and stimulating provocative new questions.

167 Provocative new studies establish the chromatin organize

168 RECENT FINDINGS: Provocative new studies highlight the interplay between

169 A provocative new study rearranges the base of the dinosau

170 This lends support to the provocative notion of "virtuous violence" put forth by F

171 ur in vivo and in vitro findings support the provocative notion that: 1) pattern recognition by CD14

172 nt protein BubR1 has provided evidence for a provocative novel link between aneuploidization and the

173 Igh has a provocative number and organization of CTCF-binding elem

174 This provocative observation therefore defines a potential ne

175 This is a provocative observation with important implications for

176 Several recent provocative observations have revived interest in the ro

177 andall and colleagues in this issue provides provocative observations of metabolic gradients in xenog

178 the environmental and behavioural conditions provocative of and protective against motion sickness an

179 The findings are provocative of further study to determine if HSPCs, like

180 us 45 Gy twice-daily TRT aims to confirm the provocative outcomes reported with 60 Gy twice daily in

181 Ever since May's provocative paper challenging whether 'large complex sys

182 f a single transcription factor, providing a provocative paradigm that may be of broad impact for reg

183 Finally, we analyse the provocative patterns that emerge from our overview.

184 covers a large amount of ground and offers a provocative perspective.

185 as compared to standard clinical tests, the provocative perturbations illuminate balance impairments

186 ated measurements at rest and during several provocative physiological challenges.

187 These results allude to several provocative possibilities for a dynamic role of calmyrin

188 These results suggest the provocative possibility that genetically distinct viruse

189 This finding raises the provocative possibility that Sky1p, and by extension met

190 agna Symposium on Biology of Skin focused on provocative, potentially disruptive advances, including

191 A series of provocative preclinical studies have suggested a promine

192 Provocative preclinical studies in this area prompt clin

193 We addressed this provocative proposal directly by assessing the sensitivi

194 The provocative protocol was successful in inducing scintigr

195 Based on our results, we pose the provocative question as to whether the 40 kDa nanomolecu

196 a broader perspective, this study raises the provocative question of how to make use of the valuable

197 antigen HLA-A*0201 in atomic detail, raising provocative questions about beta chain function.

198 age further paleogenomic research to address provocative questions about the world's most produced ce

199 citly unpaired stimulus presentations raises provocative questions as to how noncoincidence is detect

200 Here, Lenski answers provocative questions from Jeremy Fox about his iconic "

201 ichment in bone metastasis, raised even more provocative questions on the role of ER in cancer-bone i

202 re recently derived eukaryotic groups, raise provocative questions regarding models of protist evolut

203 cer effect of aspirin represents one of the 'Provocative Questions' in cancer research.

204 Among the more provocative recent findings are UVM, an SOS-independent

205 In a provocative recent paper in Science Translational Medici

206 in cargo capture at the cell surface, and a provocative recent proposal is that discrete endocytic c

207 ic poles indicated strong clustering, with a provocative regularity at 128h-1 Mpc.

208 These brain responses possess a provocative relationship to those associated with negati

209 Finally, a provocative report demonstrates that a low-fat elemental

210 xpected interactions with other pathways and provocative reports on the role of VEGFA in regenerative

211 chemistry continues to be a fascinating and provocative research topic.

212 ding human-interspecies chimeras, they are a provocative resource for achieving regenerative medicine

213 cic operations have been performed with some provocative results and limited, defined advantages.

214 These provocative results indicate that AEG-1 may play a cruci

215 These provocative results suggest that TERT promoter mutations

216 Based on these provocative results, a granular understanding of these p

217 ir approach is fresh and creative and yields provocative results.

218 s have been used in preclinical studies with provocative results.

219 ng an anti-CD19 antibody were reported, with provocative results.

220 A collection of provocative reviews in this thematic series discusses th

221 ce risk, while patients without identifiable provocative risk factors have a recurrence risk of appro

222 free cholesterol in plaques and point to its provocative role in lesion destabilization.

223 promoting sterile ALI and suggest downstream provocative roles for cysteinyl leukotrienes and protect

224 ghlights some of the recently discovered and provocative roles for ubiquitination in the regulation o

225 r, HSP65 was administered prior to a single, provocative secondary challenge.

226 Our central hypothesis was that provocative sensorimotor perturbations, delivered in a h

227 Nevertheless, several provocative similarities between different groups of suc

228 displayed normal cardiac growth responses to provocative stimulation, including ligand stimulation of

229 iac structure and function in the absence of provocative stimulation.

230 form that often is a maladaptive response to provocative stimuli such as hypertension and aortic valv

231 tonomic responses to socially significant or provocative stimuli, and in the modulation of the neurot

232 gonizing apoptotic cell death in response to provocative stimuli.

233 oconstriction, and airway hyperreactivity to provocative stimuli.

234 t instead reflect increased attention to the provocative stimulus or attempts by the intruder to 'cop

235 vity of bioenergetic pathways, and suggest a provocative strategy to treat primary mitochondrial diso

236 Provocative stress testing (exercise stress testing and

237 inical presentation, myocardial perfusion on provocative stress testing, and management of children w

238 hemia as identified by recurrent symptoms or provocative stress testing.

239 ife, patient satisfaction, rates of positive provocative stress tests, voiding dysfunction, or advers

240 The provocative stretch amplitude required to cause active f

241 The provocative stretch amplitude required to cause active f

242 Ste24, with its provocative structure, enigmatic mechanism, and recently

243 Provocative studies in mice showed that FIX-Padua exhibi

244 heir associated splicing factors, but recent provocative studies point to a key function of chromatin

245 Several recent provocative studies suggest that fMRI in unresponsive pa

246 A provocative study by Ourednik et al. published in Scienc

247 In a provocative study published in the current issue, Zylber

248 a C3/C5-dependent pathway.Significance: This provocative study suggests that inhibiting complement ac

249 Some of the findings are provocative, such as the possibility of parallel and ant

250 My goal is to provide an entertaining, even provocative, synopsis of this important but under-studie

251 bed bonding outcomes makes these macrocycles provocative synthetic targets.

252 We identified provocative targets, including 20 transcripts whose expr

253 ation timing is determined and demonstrate a provocative temporal coincidence between the establishme

254 inistration does not appear to be a suitable provocative test for diagnosing OXT-D in HHD.

255 Therefore, identifying a provocative test to diagnose an OXT-D will be important.

256 Fourteen/42 (33%) had inducible ischemia on provocative testing (group 1, 32%; group 2, 38%; group 3

257 nary syndromes, guidelines recommend routine provocative testing after negative cardiac biomarkers.

258 low reserve and microcirculatory resistance, provocative testing for endothelial dysfunction and coro

259 testing with cardiac markers, ECGs and then provocative testing over a 14-hour period, are feasible,

260 Routine provocative testing to detect ischemia before emergency

261 Provocative testing using, brinzolamide, however, reveal

262 Provocative testing with mydriatic agents (tropicamide a

263 Here, a potential role for advanced or provocative testing, including evaluation of hemodynamic

264 manifested recurrent ischemia at rest or on provocative testing.

265 agents have been historically described for provocative testing.

266 myocardial hypoperfusion during noninvasive provocative testing.

267 Alternative provocative tests or biomarkers should be explored.

268 expanded repertoire of type 2 and 3 assays, provocative tests that will allow us to determine how se

269 Once considered provocative, the notion that the wisdom of the crowd is

270 Although provocative, the theory is overly elastic.

271 This provides novel provocative therapeutic implications based on the target

272 c herpes simplex virus (oHSV), have produced provocative therapeutic responses in patients with gliob

273 Importantly, these findings suggest provocative therapeutic targets for patients with lympha

274 ble and irreversible pulmonary hypertension, provocative therapies are used, and baseline and the pos

275 While provocative, these findings do not address the selective

276 Cassel's provocative thesis was anchored in a cogent synthesis of

277 It is provocative to speculate that extrahepatic HCV diversity

278 ction of the occipital cortex to other, less provocative visual stimuli.

279 n significantly adapt to a multidirectional, provocative, visual environment after 4-5 repeated sessi

280 ing in these neural progenitors resonates in provocative ways with an older body of literature on PDG

281 urothelial cells from elderly individuals is provocative with respect to a possible link between agin

282 The in-frame CDK6-MLL transcript is provocative with respect to a potential contribution of

283 This provocative work clearly runs counter to prevailing orth

284 Provocative work is being done to clarify the concept of