ライフサイエンスコーパス: proximal promoter

1 onarily conserved G:C-rich regions in the Th proximal promoter.

2 and this occurred only from an unannotated, proximal promoter.

3 r, proximal enhancer and downstream from the proximal promoter.

4 tial contact between a distal enhancer and a proximal promoter.

5 hypoxia-response element (HRE) in the PD-L1 proximal promoter.

6 reased histone methylation (H3K27me3) in the proximal promoter.

7 teractions between the PU.1 enhancer and its proximal promoter.

8 g to the hypoxia-response element in the AXL proximal promoter.

9 er hypoxia by directly binding the TGF-beta1 proximal promoter.

10 an enrichment of acetylated-histone on their proximal promoter.

11 conserved neural crest enhancer of the Pax3 proximal promoter.

12 ds to a yet unidentified CRE site within the proximal promoter.

13 f direct binding of RBP-jkappa to the Nkx6.1 proximal promoter.

14 nhancer by looping its position close to the proximal promoter.

15 ription directly by binding two ROREs in its proximal promoter.

16 t of Wnt/beta-catenin signaling on the Runx2 proximal promoter.

17 ing to the GC-rich elements in the p21(Cip1) proximal promoter.

18 conserved ATTA sites located within the GnRH proximal promoter.

19 longation via the release of Pol II from the proximal promoter.

20 c-JUN and ATF2 to two AP-1 sites within the proximal promoter.

21 an NDR, whereas NANOG has a clear NDR at its proximal promoter.

22 a binding sites are conserved in the RCAN1-4 proximal promoter.

23 o T-cell factor/LEF-binding sites within the proximal promoter.

24 D response elements (VDREs) located near the proximal promoter.

25 ensus binding site/DA-motif in the rodent Th proximal promoter.

26 that TBX2 requires EGR1 to target the NDRG1 proximal promoter.

27 s binding to a 10-bp region of the TbetaRIII proximal promoter.

28 cription factors NF-Y and USF1 with the CP27 proximal promoter.

29 and three GC boxes, located within the Tesc proximal promoter.

30 interaction between a distal enhancer and a proximal promoter.

31 SNPs determined by sequence analysis of the proximal promoter.

32 AD, via distinct binding elements within the proximal promoter.

33 a putative Gli binding site in the col15a1b proximal promoter.

34 lpha-binding consensus sequence in the ErbB3 proximal promoter.

35 by two HNF1 sites and two C/EBP sites in the proximal promoter.

36 tive hypoxia-response element in the miR-210 proximal promoter.

37 s mediated by two adjacent Ets motifs in the proximal promoter.

38 thylating the specific CpG sites on IL-1beta proximal promoter.

39 ation of distal CGIs, despite methylation at proximal promoters.

40 ed by p53 via p53 response elements in their proximal promoters.

41 he CYP3A4 (-243/-220) and CYP3A7 (-242/-219) proximal promoters.

42 scription via tandem binding events at their proximal promoters.

43 dent manner and facilitated demethylation of proximal promoters.

44 dent on persistent STAT5 activation at these proximal promoters.

45 on the chromatin at 463 genomic positions in proximal promoters.

46 ain ectopically expressing DRAK2 via the lck proximal promoter (1017-DRAK2 Tg mice).

47 f its endogenous target, locating within the proximal promoter -242 site of the atrial natriuretic fa

48 cts, characterizing 2 common variants in the proximal promoter, A-296C and A-261T, using transfection

49 ene did not alter the hyperosmotic status of proximal promoter activities and transcription of key To

50 The risk allele (T) at rs922483 reduced proximal promoter activity and modulated alternative pro

51 ntation-dependent positive regulator of IL13 proximal promoter activity in transiently transfected, a

52 quence fused to lacZ were generated and RPGR proximal promoter activity was analyzed by X-gal stainin

53 A decrease in CCN2 expression and proximal promoter activity was observed in NP cells afte

54 cally with TNF-alpha and LPS to induce CXCL1-proximal promoter activity.

55 olymerase II 2 (ELL2) were recruited to this proximal promoter after P-TEFb release and were required

56 -16.5 ECR physically interacts with the CCL2 proximal promoter after TNF-alpha stimulation.

57 anscription regulatory domains: an inducible proximal promoter, an upstream silencer (PAUSE-1), and a

58 We targeted the PTEN proximal promoter and 5' untranslated region with dCas9

59 involves two principal regulatory regions, a proximal promoter and a distal enhancer located in the m

60 iR-200b approximately 200a approximately 429 proximal promoter and activates miR-200 expression in ep

61 s known about chromosomal loopings involving proximal promoter and distal enhancer elements regulatin

62 ases the degree of SIN3A binding to both the proximal promoter and enhancer of the Cyp1a1 gene and de

63 Rpgr-cko mice, in which the proximal promoter and first exon were deleted ubiquitous

64 ered two conserved CArG boxes located in the proximal promoter and first intron of the human KCNMB1 g

65 eases in AAR-induced EGR1 binding within the proximal promoter and highly inducible binding to a site

66 y linked with a 16-base pair deletion in the proximal promoter and inability of the upstream DNA sequ

67 tion initiating site, interacts with the MYC proximal promoter and induces orientation-independent MY

68 y, USF1 interacts with the E-box of the CP27 proximal promoter and NF-Y interacts with the CCAAT-box.

69 evolutionarily conserved X-box in the ALMS1 proximal promoter and present evidence that these protei

70 Mechanistically, Twist1 binds to Foxa1 proximal promoter and recruits the NuRD transcriptional

71 ect binding to an 11-bp fragment of the VEGF proximal promoter and that it functions as a negative re

72 t transcript of Runx3 that is derived from a proximal promoter and that produces functional protein i

73 raction of nuclear receptors with the Cyp7a1 proximal promoter and the expression of regulatory signa

74 This study reveals that Mesp1 binds to the proximal promoter and transactivates Etv2 gene expressio

75 silencer elements to directly interact with proximal promoter and transcription start sites, potenti

76 sequence (kappaB-site) was identified in the proximal promoter and was demonstrated to be required fo

77 resulted in fivefold activation of the CCN2 proximal promoter and, of importance, that small interfe

78 response elements (RAREs) within target gene proximal promoters and enhancers.

79 H3K9Ac), the enrichment of H3K9Ac in miR-29a proximal promoter, and miR-29a transcription in high glu

80 ially contained NF-Y-binding motifs in their proximal promoters, and notably enriched genes related t

81 oincident hypermethylation of the PPARgamma2 proximal promoter; and elevated circulating adiponectin.

82 Type 1 deletions remove exon 1 and the proximal promoter, appear to be RAG-mediated, and are as

83 to demonstrate that H3 histones at the Rgs10 proximal promoter are deacetylated in BV-2 microglia fol

84 -1) response elements in the murine SerpinB2 proximal promoter are essential for optimal LPS-inducibi

85 In this study, we show that KIR proximal promoters are densely methylated in less mature

86 d contain CLOCK:BMAL1 binding sites on their proximal promoters are likely to be clock-controlled TFs

87 e proteins were found to be recruited to the proximal promoter area of Cdx2.

88 hylation status of specific CpG sites of the proximal promoter, as well as by the actions of differen

89 use studies have shown that enhancers in the proximal promoter between -172/-1 bp of the ovine FSHB g

90 uding factors with strong preferences toward proximal promoter binding, factors that target intergeni

91 While the proximal promoter binds to specific transcription factor

92 The use of DNase I accessibility to define proximal promoter borders revealed that about half of pr

93 usly characterized GC-rich region in the p21 proximal promoter but also by occupancy at a novel, phyl

94 ajority of TRbeta1 binding sites were not in proximal promoters but in the gene body of known genes.

95 jority of MNase hypersensitive sites marking proximal promoters, but also 3' ends of maize genes.

96 anscription factor Yin Yang 1 (YY1) in their proximal promoters, but the physiological relevance is u

97 interaction site was identified in the Ctgf proximal promoter by ChIP-on-chip assay.

98 nd that SIRT1 is recruited to the E-cadherin proximal promoter by ZEB1 to deacetylate histone H3 and

99 wherein actions of ERalpha and Sin3A at the proximal promoter can overcome activating signals at dis

100 in the distal 3' flanking region of the CP27 proximal promoter CCAAT box.

101 ave shown that NF-Y interacted with the CP27 proximal promoter CCAAT-box.

102 further define a 0.3-kb sequence including a proximal promoter (cluster A1) and an enhancer (cluster

103 mark, specifically H3K9me3, around the NDRG1 proximal promoter coincident with the recruitment of the

104 Cotransfection of HepG2 cells with a CYP3A4 proximal promoter construct and expression vectors for t

105 we have identified a ternary complex at the proximal promoter containing TFAP2C, the oncoprotein Myc

106 ics analysis showed that the human SKIL gene proximal promoter contains a TGF-beta response element (

107 chanisms relieve the elongation block at the proximal promoter: demethylation and recruitment of andr

108 issue and EMSA experiments with the human Th proximal promoter did not detect ER81 binding to the Th

109 Genome-wide proximal promoter DNA methylation analysis suggested dif

110 Proximal promoter DNA methylation has been shown to be i

111 cer elements into close association with the proximal promoter elements bound by CONSTANS (CO).

112 can function in essentially the same way as proximal promoter elements.

113 s with the recruitment of HDAC2 to the hTERT proximal promoter, enhancing localized histone H3-K9 ace

114 e region between -128 and -88 as the minimal proximal promoter essential for basal transcription of A

115 d by the reduction of PAF1c occupancy at the proximal promoter estrogen-responsive elements.

116 a sizable fraction of genes with methylated proximal promoters exhibit elevated expression.

117 wborn thymi, both pLckCre and endogenous Lck proximal promoter expression were substantially enhanced

118 DNA methylation at proximal promoters facilitates lineage restriction by si

119 ipitation we find dismissal of CtBP from the proximal promoter following DNA-damage, and that PARP1 a

120 Here, we report that DNA methylation of the proximal promoter for the type III deiodinase (dio3) gen

121 A large number of distal enhancers and proximal promoters form enhancer-promoter interactions t

122 e GATA site in intron 8 (int-8-GATA) and the proximal promoter, forming a long-range loop to enhance

123 nalysis in zebrafish, we report here an etv2 proximal promoter fragment that prevents transgene misex

124 A 230-bp proximal promoter fragment, necessary for transcription

125 higher eukaryotes, these factors shield the proximal promoter from the action of more distant transc

126 Here, we show that the proximal promoter from the Rhox5 homeobox gene recruits

127 ed transcription factor binding sites in the proximal promoters (from 100 bp to 5 kb upstream) of hum

128 functions of DNA methylation beyond those of proximal promoter gene regions.

129 In mitosis, proximal promoters generally maintain their accessibilit

130 ontain a SMAD-binding element (SBE) in their proximal promoters; however, mutation of the putative SB

131 In silico analysis of the Ccn2 proximal promoter identified multiple consensus TCF x LE

132 ll cultures using methylated tissue-specific proximal promoters identified half-CRE (CGTCA) and half-

133 locates to the nucleus and binds to the CCN2 proximal promoter in an APF-dependent manner, providing

134 nscription factor (REST) occupied the Gabra6 proximal promoter in CGN progenitors and early postmitot

135 d NF-kappaB bind and/or are recruited on the proximal promoter in chromatin immunoprecipitation (ChIP

136 nd decreased HIF-2alpha binding to the MMP13 proximal promoter in chromatin immunoprecipitation assay

137 NX3 protein represses transcription from the proximal promoter in T cells.

138 sm of transcription of genes with methylated proximal promoters in a tissue-specific fashion.

139 erved W/S-X-Y core module of the MHC class I proximal promoters, including the RFX factor components

140 ession through two Glis-binding sites in its proximal promoter, indicating that Glis3 also regulates

141 ssed the transactivation activity of the E1b proximal promoter, indicating their importance as contri

142 on identifying and characterising the ALMS1 proximal promoter, initially by using 5' RACE to map tra

143 ription from the dnaA promoter and an origin-proximal promoter involved in replication initiation is

144 kappaB activation, the NF-kappaB site in the proximal promoter is not required.

145 er, the ER81 binding site/DA-motif in the Th proximal promoter is poorly conserved in other mammals.

146 (TSSs), and a 105-bp fragment containing the proximal promoter is responsive to vIRF4/RTA.

147 ary conservation of TFBEs within orthologous proximal promoters is closely linked to function, define

148 scriptional enhancer sequences interact with proximal promoters is poorly understood within the conte

149 eam CGI and a lack thereof at the methylated proximal promoter itself.

150 f a G-rich sequence located within the c-KIT proximal promoter (kit2) in the presence of monovalent c

151 onsensus binding motif within the MIP-3alpha proximal promoter leading to increased protein secretion

152 the expression variance is not explained by proximal promoter methylation, with the exception of gen

153 ed keratinocytes does not involve changes in proximal promoter methylation.

154 ining a cAMP response element (CRE) in their proximal promoter, more than half of which are conserved

155 ic variation at the NPY locus, especially in proximal promoter nabla-880Delta, disrupts glucocorticoi

156 demonstrated that EWS-WT1 directly bound the proximal promoter of ASCL1, activating its transcription

157 d CES1 expression by directly binding to the proximal promoter of CES1.

158 ied a highly conserved 13-bp sequence in the proximal promoter of COX4I2 that functions as an oxygen

159 EMSA identified a ZBP-89-binding site in the proximal promoter of CTNNB1 Reciprocally, siRNA-mediated

160 inant GPATCH3 protein activated in vitro the proximal promoter of CXCR4, a gene involved in embryo ne

161 ng with a luciferase reporter containing the proximal promoter of ER.

162 d that hypoxia response element sites in the proximal promoter of ET-1 and ET-BR were required for th

163 FLI1 associates with the GGAA repeats in the proximal promoter of FATE1, which exhibits accessible ch

164 potential ERRalpha response elements in the proximal promoter of human OPN showed that ERRalpha and

165 ulation, we identified a 70-bp region in the proximal promoter of IDOL, distinct from that containing

166 le from The Jackson Laboratory, in which the proximal promoter of Lck drives Cre expression, is a com

167 ed a functional cAMP response element in the proximal promoter of Lrrtm2, indicating that at least Lr

168 a repressive chromatin state surrounding the proximal promoter of Rac1.

169 tation revealed that Kdm5b is present at the proximal promoter of Reln, and H3K4me3 methylation was i

170 interactions between the distal enhancer and proximal promoter of rhodopsin and long/medium-wavelengt

171 is-elements for FoxOs and Clock/Bmal1 in the proximal promoter of the Atg14 gene.

172 monstrated enhanced binding of the AR to the proximal promoter of the CEBPB gene in the presence of d

173 l ROR response element was identified in the proximal promoter of the FGF21 gene and shown to exhibit

174 The proximal promoter of the human and mouse caveolin-1 (CAV

175 tide polymorphism, we have characterized the proximal promoter of the mouse p18 gene.

176 In addition, we observed that the proximal promoter of the Numb gene had functional Tcf bi

177 that endogenous Prox1 directly binds to the proximal promoter of the Olig2 gene locus, as well as to

178 at ERG could bind to functional sites in the proximal promoter of the RhoJ gene.

179 We also show that estrogen acts on the proximal promoter of the S6K1 gene in a mechanism involv

180 iated with an increase in methylation of the proximal promoter of the serotonin transporter gene, whi

181 f the general transcription machinery to the proximal promoter of their target genes.

182 ng expression of IkappaBalpha by binding the proximal promoter of this gene.

183 n insulator-binding factor CTCF binds to the proximal promoter of VEGF.

184 intergenic regions and gene bodies flanking proximal promoters of a large cohort of transcriptionall

185 emethylation of enhancer elements within the proximal promoters of AREG and EREG.

186 ofiling the dynamic interaction of p300 with proximal promoters of human T cells identified a class o

187 ated CREB constitutively associated with the proximal promoters of many of the induced target genes i

188 NLRC5 associates with and transactivates the proximal promoters of MHC class I genes, although the mo

189 androgen receptor (AR) binding sites in the proximal promoters of Mmp9, Snai3, and Spp1.

190 he methylation of different CpG sites in the proximal promoters of the human MMP13 and IL1B genes mod

191 on (STAT) binding elements (SBEs) within the proximal promoters of the MMP-1 and MMP-3 genes, which i

192 The proximal promoters of these genes were then analyzed for

193 actor 1 (Lef-1) differentially regulates the proximal promoters of these two genes.

194 rate a reduction of p65 occupancy within the proximal promoters of those genes.

195 gulation by putative functional variants via proximal promoter or distal enhancer-promoter interactio

196 ACs) differentially bind to various RAREs in proximal promoters or enhancer regions of RA-regulated g

197 d potentially deliver RNA polymerase II to a proximal promoter, or alternatively might function direc

198 While the proximal promoter (P(R7)) is active in the bundle sheath

199 ssive elongation of RNA Polymerase II from a proximal promoter paused state is a rate-limiting event

200 cers in gene-rich neighborhoods, rather than proximal promoters, preventing straightforward assignmen

201 st critical oncogenes, forms a DNA G4 in its proximal promoter region (MycG4) that functions as a tra

202 nsulin in non-tumor pituitary cells, but the proximal promoter region (nucleotides -496/+1) responds

203 CAF was increasingly recruited to the MMP-13 proximal promoter region after PTH treatment, and this w

204 I, p300, Oct4, Sox2, and Tet1 from the Nanog proximal promoter region and with no increase in repress

205 active chromatin marks (acetylation) at its proximal promoter region as well as increased cyclic ade

206 Vascular endothelial growth factor (VEGF) proximal promoter region contains a poly G/C-rich elemen

207 In this study, we show that the proximal promoter region from -150 to +72 of the mouse A

208 Our study defined the human RPGR proximal promoter region in which a 3-kb fragment contai

209 in/TCF4 complex, including by binding to the proximal promoter region of ABCG2, a CSC marker.

210 /E-cadherin complex, which then binds to the proximal promoter region of CASP3.

211 oth endogenous Sp1 and Sp3 were bound to the proximal promoter region of E1b.

212 ecipitation revealed that MYST3 binds to the proximal promoter region of ERalpha gene, and inactivati

213 to tandem cAMP-response element sites in the proximal promoter region of Foxo1 gene.

214 C5 localized to the nucleus and occupied the proximal promoter region of H-2 genes.

215 amma is mediated by STAT1 recruitment to the proximal promoter region of Ncx1.

216 tional repressor complex mSin3A-HDAC1 at the proximal promoter region of OGA and correspondingly decr

217 essor Fep1, which strongly associates with a proximal promoter region of shu1(+) in vivo in response

218 The 5' flanking proximal promoter region of the AKR1C1 gene consists of

219 lar analysis reveals that PRMT5 binds to the proximal promoter region of the AR gene and contributes

220 an ATP-dependent chromatin remodeler, on the proximal promoter region of the AR gene.

221 hippocampal cell line stably expressing the proximal promoter region of the arginase 1 gene fused to

222 hat IkappaBzeta is directly recruited to the proximal promoter region of the Ccl2 gene and is require

223 ound to E-box cis-regulatory elements in the proximal promoter region of the E-cadherin gene.

224 th this suggestion, Brd4 associates with the proximal promoter region of the Gli1 locus, and does so

225 Herein, we have cloned and characterized the proximal promoter region of the human AKR1C1 gene.

226 The polypurine/polypyrimidine tract in the proximal promoter region of the human RET gene (-51 to -

227 This study aims to characterize the proximal promoter region of the human RPGR gene.

228 g a construct consisting of a portion of the proximal promoter region of the mouse COX-2 gene upstrea

229 The G-quadruplex formed in the proximal promoter region of the MYC oncogene (MycG4) has

230 y forkhead transcription factor FoxO3 to the proximal promoter region of the Pcsk9 gene and deacetyla

231 s indicate that FoxO1 can associate with the proximal promoter region of the srebp1 gene and disrupt

232 0 (RIP140) for heterochromatinization on the proximal promoter region of this gene locus.

233 CHD4 directly binds the proximal promoter region of Ucp1, which is displaced upo

234 -quadruplexes have been shown to form in the proximal promoter region of VEGF and are amenable to sma

235 estrogen-response element located within the proximal promoter region that is also targeted by ERalph

236 on between remote enhancer sequences and the proximal promoter region through "looping" of intervenin

237 ypoxia response elements in the human eIF4E1 proximal promoter region to activate eIF4E1 expression.

238 d that constitutively bound ELK1 at the EGR1 proximal promoter region was phosphorylated after AAR ac

239 on elements (MAREs) from the sequence in the proximal promoter region where Nrf2 may bind.

240 d CtBP-responsive repression elements to the proximal promoter region, and found ZBRK1 overexpression

241 ding of pICln (but not vice versa) to the AR proximal promoter region, suggesting that PRMT5 recruits

242 via chromatin remodeling specifically in the proximal promoter region.

243 ed transcription factor binding sites in the proximal promoter region.

244 revealed several cis-acting elements in the proximal promoter region.

245 en-response element (ERE) located within the proximal promoter region.

246 bromodomain containing 4 (BRD4) in the NRP1 proximal promoter region.

247 he research effort in this area has examined proximal promoter regions and epigenetic alterations at

248 nhancer-binding protein delta (C/EBP) to the proximal promoter regions and STAT3 to the distal promot

249 elements mediate chromatin accessibility in proximal promoter regions and the repeat content of prom

250 distinguishes binding between distal versus proximal promoter regions as well as the 3' ends of gene

251 nd PGR binding sites were highly enriched in proximal promoter regions in close proximity to H3K27ac-

252 evealing, and sequencing the IER3 coding and proximal promoter regions of 74 MDS patients disclosed n

253 Site-specific CpG methylation within the proximal promoter regions of approximately 14,500 genes

254 binding domain of ER and is recruited to the proximal promoter regions of ER target genes upon gene i

255 differential patterns of DNA methylation in proximal promoter regions of most (eg, CD31, von Willebr

256 sly found that SUMO-1 marks chromatin at the proximal promoter regions of some of the most active hou

257 ndard exome capture, we included genome-wide proximal promoter regions that contain sequences that re

258 romoters are common and are more likely than proximal promoter regions to show differentiation-specif

259 Analysis of DNA methylation at proximal promoter regions uncovered >250 genes harbourin

260 t or susceptible, share the identical coding/proximal promoter regions, but vary in the upstream regu

261 n-specific enhancer, I12b, and the Dlx1/Dlx2 proximal promoter regions, through repressor E2F sites b

262 binding peaks show a striking enrichment in proximal promoter regions, with 52% located within 1 kb

263 r alpha (ERalpha) and FOXA1 binding in their proximal promoter regions.

264 associated with increased H3K4me2 levels at proximal promoter regions.

265 is maintained by DNA methylation within the proximal promoter regions.

266 When MHC-II genes are expressed, their proximal promoter regulatory regions reorganize to the f

267 Analysis of the COL1A2 proximal promoter revealed a noncanonical CArG box (CCAA

268 A proximal promoter sequence (-8 to +33 bp) of Frmpd1 bind

269 wo additional mutations within the conserved proximal promoter sequence (c.-274T>G and c.-307T>C).

270 ed a potential SP6 binding motif in the AMBN proximal promoter sequence and showed that wild-type (WT

271 variants in a conserved region of the OVOL2 proximal promoter sequence in the index families (c.-339

272 We confirm recruitment to proximal promoter sequences in MHC class II genes and mo

273 Proximal promoter sequences of expressed genes are hypom

274 over the typical baseline approach of using proximal promoter sequences.

275 Even though the Hoxa1 RARE and proximal promoter show high levels of H3K9,K14 acetylati

276 Analysis of CYR61 proximal promoter showed that a sequence conforming to t

277 n was significantly associated with the IL-6 proximal promoter single nucleotide polymorphism (SNP) r

278 The proximal promoter site also contributes to pqsR transcri

279 cate that NF-Y is not merely a commonly used proximal promoter TF, but rather performs a more diverse

280 Despite being characterized as a proximal promoter TF, only 25% of NF-Y sites map to prom

281 We characterized a Notch1 proximal promoter that contains p53 canonical response e

282 stic regulation of KIRs by the bidirectional proximal promoter, the specificity of inhibitory KIRs on

283 duced VDR/RXR binding to the VDRE-containing proximal promoter, the VDR/RXR heterodimer also localize

284 nd determines the chromatin structure of the proximal promoter to allow gene expression.

285 ments and trans factors interacting with the proximal promoter together with a long noncoding RNA (ln

286 on, it undergoes a switch from a distal to a proximal promoter usage, accompanied by a switch from po

287 leotide polymorphism analyses indicated that proximal promoter variant nabla-880Delta (2-bp TG/-, Ins

288 ring the chromatin structure around the HAS2 proximal promoter via O-GlcNAcylation and acetylation.

289 To get some insight into this process, AGAP2 proximal promoter was cloned and characterised using rep

290 Decreased PXR binding to the CYP3A4 proximal promoter was found in FGF21-treated Huh7 cells.

291 rope-specific regulation associated with the proximal promoter was observed as expected, but the mode

292 by activator protein 1 (AP-1) binding on the proximal promoter was sensitive to inhibition of de novo

293 stitutions at positions -331 and -164 in the proximal promoter were each sufficient to account for th

294 CpG dinucleotides in the proximal promoter were highly methylated in the crypt an

295 xpression from both distal promoter (Pd) and proximal promoter, whereas MS-275 and ATO induced gene e

296 ession of STARS in vitro activates the STARS proximal promoter, which contains a conserved SRF site.

297 an enhanced binding of HDAC3 to the sGCbeta1 proximal promoter, which could be reversed by panobinost

298 Many AR binding events occur at proximal promoters, which can act as enhancers to augmen

299 atin immunoprecipitations of the osteocalcin proximal promoter with antibodies against Runx2 demonstr

300 models specifically in the CR1 region of its proximal promoter, with the insertion of a nucleosome an