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1 rabies virus (PRV) is the causative agent of pseudorabies, a disease of great economic and welfare im
5 two isogenic strains of a neurotropic virus (pseudorabies, Bartha) tagged with either green or red fl
10 of the advantages and limitations of herpes, pseudorabies, rabies, adeno-associated, lentivirus, and
11 d using green fluorescent protein expressing pseudorabies virus (GFP-PRV) to (1) characterize age-dep
13 itreal injection of the attenuated strain of pseudorabies virus (PRV Bartha) results in transneuronal
14 ntraocular injection of the Bartha strain of pseudorabies virus (PRV Bartha) results in transsynaptic
15 rus (HSV), varicella-zoster virus (VZV), and pseudorabies virus (PRV) all utilize a complex of two gl
16 well as for the animal herpesviruses porcine pseudorabies virus (PRV) and bovine herpesvirus 1 (BHV-1
17 entified by immunohistochemical detection of pseudorabies virus (PRV) and corticotropin-releasing fac
18 ative to the model alphaherpesvirus pathogen pseudorabies virus (PRV) and demonstrate that this criti
19 are the most widely used method to visualize pseudorabies virus (PRV) and herpes simplex virus (HSV)
20 he gD glycoprotein of the alphaherpesviruses pseudorabies virus (PRV) and herpes simplex virus 2 (HSV
22 9p and the glycoprotein heterodimer gE/gI of pseudorabies virus (PRV) and herpes simplex virus type 1
24 3 in herpes simplex virus type 1 (HSV-1) and pseudorabies virus (PRV) and ORF66 in varicella-zoster v
25 ane proteins encoded by the alphaherpesvirus pseudorabies virus (PRV) are internalized after reaching
29 the viral transcriptional activator, VP16 on pseudorabies virus (PRV) escape from genome silencing.
32 d PSPMNs by using recombinant strains of the pseudorabies virus (PRV) for trans-synaptic tract tracin
33 d PSPMNs by using recombinant strains of the pseudorabies virus (PRV) for transsynaptic tract-tracing
34 pothesis, we used recombinant strains of the pseudorabies virus (PRV) for transsynaptic tract-tracing
35 rograde transport of an attenuated strain of pseudorabies virus (PRV) from the nucleus accumbens was
37 determine the role of internalization of the pseudorabies virus (PRV) gE and gI proteins, we construc
42 ynaptic tracing with peripheral injection of pseudorabies virus (PRV) has been extensively characteri
44 using transneuronal retrograde transport of pseudorabies virus (PRV) in normal animals and in animal
45 ction of the transneuronal retrograde tracer pseudorabies virus (PRV) in rats, we previously localize
47 esviruses herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV) in the infected cell cytoplasm
48 cellular virions and axonal assemblies after pseudorabies virus (PRV) infection of cultured neurons.
50 the host gene expression profile after acute pseudorabies virus (PRV) infection of the CNS using Affy
51 models of viral egress from neurons by using pseudorabies virus (PRV) infection of the rat retina: do
52 nal spread of herpes simplex virus (HSV) and pseudorabies virus (PRV) infection, a culture system con
53 nduced after herpes simplex virus type 1 and pseudorabies virus (PRV) infections of rat embryonic fib
55 ed by retrograde trans-synaptic migration of pseudorabies virus (PRV) injected into the adrenal gland
56 Using the retrograde, transsynaptic tracer pseudorabies virus (PRV) injected into the BAT of mice,
57 astric nerves transected, were infected with pseudorabies virus (PRV) injected into the external uret
58 ia the transsynaptic retrograde transport of pseudorabies virus (PRV) injected into the kidneys of ra
59 ted neurons in the preoptic region following pseudorabies virus (PRV) injections into either the supe
61 sneuronal tracing studies using injection of pseudorabies virus (PRV) into either the diaphragm or re
62 studied after injecting the Bartha strain of pseudorabies virus (PRV) into the sciatic nerve to provi
63 epithelial cells, alphaherpesviruses such as pseudorabies virus (PRV) invade axons of peripheral nerv
69 mal degradation of KIF1A in axons.IMPORTANCE Pseudorabies virus (PRV) is an alphaherpesvirus related
74 by inoculating the ventral stomach wall with pseudorabies virus (PRV) on postnatal day 1 (P1), P4, or
75 simplex virus (HSV) entry activity, but not pseudorabies virus (PRV) or bovine herpesvirus 1 (BHV-1)
76 d the retrograde transneuronal tracer Bartha-pseudorabies virus (PRV) or the retrograde marker choler
77 ane protein present in the lipid envelope of pseudorabies virus (PRV) particles in a unique tail-anch
79 In this report, we describe construction of pseudorabies virus (PRV) recombinants that efficiently e
80 escape from latency by the alphaherpesvirus pseudorabies virus (PRV) relies on a structural viral te
81 ial cells infected with the alphaherpesvirus pseudorabies virus (PRV) results in activation of the ha
84 rted methods we solved the structures of (i) Pseudorabies virus (PRV) RNA G-quadruplex and ligand com
85 stem, we have discovered a novel role of the pseudorabies virus (PRV) serine/threonine kinase US3 in
87 After intraocular injection of the virulent pseudorabies virus (PRV) strain Becker into late-stage c
89 , but partial deletions generated in HSV and pseudorabies virus (PrV) suggest an additional function
90 egulates interferon (IFN) induction and that pseudorabies virus (PRV) targets PRDX1 to evade IFN indu
92 ly(A) fraction of the lytic transcriptome of pseudorabies virus (PRV) throughout a 12-hour interval o
94 ns were identified by immunogold labeling of pseudorabies virus (PRV) transported retrogradely and tr
95 UL13 protein kinase of the alphaherpesvirus pseudorabies virus (PRV) triggers phosphorylation of FTO
102 In this report, we demonstrate that the pseudorabies virus (PRV) Us9 protein is present in infec
103 s simplex virus (HSV) and, as reported here, pseudorabies virus (PRV) utilize the ESCRT apparatus to
104 nal sorting and transport of fully assembled pseudorabies virus (PRV) virions is dependent on the vir
106 ingly, entry of the porcine alphaherpesvirus pseudorabies virus (PRV) was inhibited by sphingomyelin-
108 tracing experiments were performed in which pseudorabies virus (PRV) was injected into the stellate
109 riments, the retrograde transneuronal tracer pseudorabies virus (PRV) was microinjected into the CEAm
111 ade tract tracing, using isogenic strains of pseudorabies virus (PRV) with distinct fluorescent repor
112 dies, we compared gH of the alphaherpesvirus pseudorabies virus (PrV) with gH of the gammaherpesvirus
116 brane glycoproteins gE and gI are encoded by pseudorabies virus (PRV), a neurotropic, broad-host-rang
117 lenic function was accomplished by injecting pseudorabies virus (PRV), a retrograde transynaptic trac
118 that the amino-terminal one-third of gC from pseudorabies virus (PRV), a swine herpesvirus, includes
120 g vesicular stomatitis (VSV), Sindbis virus, pseudorabies virus (PRV), adeno-associated virus (AAV),
123 Previous studies showed that proteins from pseudorabies virus (PRV), an alphaherpesvirus, localize
124 work reports that the UL13 protein kinase of pseudorabies virus (PRV), an alphaherpesvirus, mediates
125 erpes simplex viruses (HSV) 1 and 2, porcine pseudorabies virus (PRV), and bovine herpesvirus 1 (BHV-
126 (BHV-1), equine herpesvirus type 1 (EHV-1), pseudorabies virus (PRV), and varicella-zoster virus (VZ
127 pesviruses, such as herpes simplex virus and pseudorabies virus (PRV), are neuroinvasive dsDNA viruse
129 including herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), are pathogens of the nervous s
130 U(S)11c119.3 cells are fully susceptible to pseudorabies virus (PRV), as shown by single-step growth
132 sviruses, herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), have suggested that UL37 plays
133 pes viruses: herpes simplex virus (HSV1) and pseudorabies virus (PrV), human immunodeficiency virus t
134 peroxidase conjugated to colloidal gold, or pseudorabies virus (PRV), into the nuclear core of the r
135 st commonly varicella-zoster virus (VZV) and pseudorabies virus (PRV), may cause cranial nerve disord
137 ls also showed enhanced fusion activity with pseudorabies virus (PRV), paramyxovirus, and rhabdovirus
140 lex virus 1 (HSV-1), HSV-2, and veterinarian pseudorabies virus (PRV), that infect the peripheral ner
142 ished retrograde transneuronal viral tracer, pseudorabies virus (PRV), was injected into the ventral
144 Using a viral transneuronal tract tracer, pseudorabies virus (PRV), we also tested whether the com
147 cle-specific injection of an mRFP-expressing pseudorabies virus (PRV), which acts as a transsynaptic
148 including herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), within neurons is poorly under
150 s study were to identify the mechanism(s) of pseudorabies virus (PrV)-induced down-regulation of porc
151 nervous system, alphaherpesviruses-including pseudorabies virus (PRV)-use retrograde axonal transport
166 emale Sprague-Dawley rats were infected with pseudorabies virus (PRV, Bartha's K-strain) by injection
167 nstructing a replication-competent strain of pseudorabies virus (PRV-263) that changes the profile of
168 were transsynaptically labeled by injecting pseudorabies virus (PRV-614) into the kidney, indicating
169 train of the retrograde transneuronal tracer pseudorabies virus (PRV-Ba) was injected into rat choroi
170 e transneuronal tracer, the Bartha strain of pseudorabies virus (PRV-Ba), were injected into the uppe
171 tract tracing using an attenuated strain of pseudorabies virus (PRV-Bartha) was combined with immuno
172 S-specific transneuronal viral tract tracer, pseudorabies virus (PRV152) and demonstrated the sensory
174 ed fluorophore expression from a recombinant pseudorabies virus (PRV263) carrying a Brainbow cassette
175 vulgaris leucoagglutinin (anterograde), and pseudorabies virus (transneuronal retrograde) tract-trac
176 g after inoculation of the stomach wall with pseudorabies virus 152, a viral label that reports enhan
177 hway with those of other alphaherpesviruses (pseudorabies virus [PRV] and herpes simplex virus 1 [HSV
178 e poliovirus, herpesvirus, rabies virus, and pseudorabies virus all utilize neuronal retrograde trans
179 following infection with the closely related pseudorabies virus and observed similar perimeters of gl
180 ynaptically labeled from the distal colon by pseudorabies virus and several of these were also retrog
182 s simplex virus, varicella zoster virus, and pseudorabies virus are neurotropic pathogens of the Alph
185 Here, using herpes simplex virus type I and pseudorabies virus as model alphaherpesviruses, we show
186 ame animals by injection of a recombinant of pseudorabies virus Bartha (PRV) into the contralateral v
187 he transsynaptic retrograde transport of the pseudorabies virus Bartha (PRV-Bartha) strain has become
188 labeling of the phrenic motoneuron pool with pseudorabies virus demonstrated a substantial number of
191 rions, epithelial cells infected by HSV-1 or pseudorabies virus following ADS express fewer than two
193 icial chromosome (BAC) containing the 142-kb pseudorabies virus genome was constructed such that the
194 sons with homologous HSV-2 gH/gL and partial pseudorabies virus gH structures support the domain boun
197 naptic labeling from the adrenal gland using pseudorabies virus identified presympathetic GABAergic n
198 ficking, we analyzed the axonal transport of pseudorabies virus in the presence and absence of pUS9.
200 sitive neurones in the LH were labelled with pseudorabies virus injected into the liver of parasympat
201 erebral cortex were identified in rats after pseudorabies virus injections were made in functionally
204 nsneuronally infected following injection of pseudorabies virus into rectus abdominis or transversus
205 injected the retrograde transynaptic tracer pseudorabies virus into single tensor tympani (TT) muscl
208 injected a retrograde-specific strain of the pseudorabies virus into the rat OB and piriform cortex.
212 resembles in many respects the phenotype of pseudorabies virus lacking glycoproteins gM, gE, and gI.
214 demonstrate that the pUL31 component of the pseudorabies virus nuclear egress complex is a condition
215 remotor interneurons with the trans-synaptic pseudorabies virus PRV-152 revealed the presence of burs
216 re retrogradely labelled (prior injection of pseudorabies virus PRV-152) and whole-cell, patch clamp
217 Specifically, we injected the conditional pseudorabies virus recombinant (BA2001) that can replica
221 ransneuronal retrograde pathway tracing with pseudorabies virus revealed connectivity between MnPO VG
223 liver and epididymal white fat in mice using pseudorabies virus strains expressing different reporter
225 omplemented prior herpes simplex virus 1 and pseudorabies virus studies investigating two other inhib
226 riments with ICP4 homologs revealed that the pseudorabies virus TAD is a potent activator of the gD p
231 n subunit b retrograde tracing from rRPa and pseudorabies virus transynaptic retrograde tracing from
234 ntral nervous system neurons infected with a pseudorabies virus were examined in vitro by using whole
235 pathway, a retrograde transsynaptic tracer (pseudorabies virus) was injected into the orbicularis oc
236 rebral injections of an attenuated strain of pseudorabies virus, a neurotropic alpha herpesvirus that
237 s in the spinal cord, was characterized with pseudorabies virus, a retrograde transynaptic tracer.
240 tructure of the N-terminal half of UL37 from pseudorabies virus, an alphaherpesvirus closely related
241 a subunit, Fluoro-Gold, the Bartha strain of pseudorabies virus, and biotinylated dextran amine.
244 ctures of gH/gL from herpes simplex virus 2, pseudorabies virus, and Epstein-Barr virus revealed dist
246 ilar mutant of the related alphaherpesvirus, pseudorabies virus, and suggests that the glycoprotein r
247 lycoproteins of herpes simplex virus type 1, pseudorabies virus, and varicella-zoster virus, BHV-1 gI
250 virus 1 (EHV-1), varicella-zoster virus, and pseudorabies virus, but very little is known about the p
251 pesviruses, such as herpes simplex virus and pseudorabies virus, cause a broad range of diseases in h
252 ine herpesvirus 1, equine herpesvirus 4, and pseudorabies virus, establish a quiescent/latent infecti
253 tween HSV1 and the related alphaherpesvirus, pseudorabies virus, in which the homologues of all three
254 ions of the SCN using the swine herpesvirus (pseudorabies virus, PRV) as a tool for transynaptic anal
256 r the retrograde transneuronal viral tracer, pseudorabies virus, was injected into the stellate sympa
257 an infectious clone of the alphaherpesvirus pseudorabies virus, we have made a collection of truncat
258 paring HSV-1 to a related alpha herpesvirus, pseudorabies virus, we show that this preferential exocy
259 /Cas9 and Cre/Lox system against re-emerging Pseudorabies virus, which caused the recent devastating
260 ry associated with the hippocampus using the pseudorabies virus-Bartha strain (PRV-Bartha) tracer in
262 and bladder body injections, the majority of pseudorabies virus-labelled cells were found in the late
273 tructed a panel of Cre recombinase-activated pseudorabies viruses (PRVs) that enabled retrograde trac
274 ell imaging, we made a series of recombinant pseudorabies viruses that encoded green fluorescent prot
276 the cervical spinal cord in which c-Fos and pseudorabies were co-localized, and these neurons expres