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1 able for determining physiological levels of psoriasin.
4 To date, the exact physiological function of psoriasin abundant in many human cell types remains uncl
6 noma in situ) mammary epithelial cells, that psoriasin and several other genes implicated in psoriasi
8 , human beta-defensin-3, cathelicidin LL-37, psoriasin) and cytokines (TSLP, IL-25, IL-32, IL-33) wer
12 plification of 121-bp sequence colinear with psoriasin cDNA, as did genomic DNA from hybrid cell line
15 onfluent conditions dramatically up-regulate psoriasin expression in MCF10A mammary epithelial cells.
18 , we show that down-regulation of endogenous psoriasin expression via stable short hairpin RNAs in a
19 nsight into regulatory pathways that control psoriasin expression, we developed polyclonal and monocl
20 labelling and demonstrated quantification of psoriasin from 250 pg ml(-1) to 10 ng ml(-1)-a concentra
24 al putative functions have been proposed for psoriasin in various disease types, but none of these ca
26 nalysis indicated that the alpha-helicity of psoriasin increases by more than 20% in the presence of
27 immune response with increased expression of psoriasin, interleukin-1beta, tumor necrosis factor alph
29 analysis of breast carcinomas confirmed that psoriasin is frequently overexpressed in estrogen recept
37 angiogenesis and worse clinical outcome, and psoriasin mRNA levels are coordinately regulated with VE
38 ally synthesized the N-terminally acetylated psoriasin of 100 amino acid residues using solid phase p
39 ng molecular inflammation, including S100A7 (psoriasin) positivity, as well as features of epidermal
40 ta6 subunit cytoplasmic tail and report that psoriasin (Psor) (S100A7) bound preferentially to the re
41 ort by Schroder and colleagues suggests that psoriasin, purified from human stratum corneum extracts,
46 of a label-free immunosensor for the protein psoriasin (S100A7), which is associated with a number of
47 ynthetic access to large quantities of human psoriasin should facilitate studies of its biological fu
48 f highly pure and correctly folded synthetic psoriasin was obtained from a single synthesis on a 0.25