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4 norepinephrine (NET) are targets of multiple psychoactive agents, and their dysfunction has been impl
5 lease and are important targets for multiple psychoactive agents, including amphetamines, cocaine, an
6 targets for a number of clinically relevant psychoactive agents, including antidepressants, cocaine,
7 partly because it is the target of multiple psychoactive agents, including the antidepressant paroxe
9 d other cannabinoids are responsible for the psychoactive and medicinal properties of Cannabis sativa
14 ed changes in Gi and Gq activity predict the psychoactive behavioral effects of a variety of pharmoco
18 ht mass spectrometer (APIM(tof)MS) to detect psychoactive cathinones and tryptamines from aqueous pha
19 et of Delta(9)-tetrahydrocannabinol (THC), a psychoactive chemical from Cannabis sativa with a wide r
20 s widely believed that cannabis, or its main psychoactive component Delta(9)-tetrahydrocannabinol (TH
21 Delta(9)-tetrahydrocannabinol (THC), a major psychoactive component found in marijuana or anandamide,
22 tetrahydrocannabinol (Delta9-THC), the major psychoactive component in marijuana, can lead to enhance
24 at in mice, subchronic administration of the psychoactive component of cannabis, delta9-tetrahydrocan
25 re to Delta(9)-tetrahydrocannabinol (THC), a psychoactive component of cannabis, on the morphological
26 trahydrocannabinol (Delta(9)-THC), the major psychoactive component of cannabis, produced dose-depend
27 elta(9)-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, results in behaviora
28 e to delta-9-tetrahydrocannabinol, the major psychoactive component of cannabis, with protracted effe
31 elta(9)-tetrahydrocannabinol (THC), the main psychoactive component of marijuana (Cannabis sativa), i
33 Delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana, and other direct ca
34 m, most popularly known as the target of the psychoactive component of marijuana, Delta(9)-tetrahydro
35 s capable of oxidatively degrading the major psychoactive component of marijuana, Delta9-tetrahydroca
36 etrahydrocannabinol (Delta(9)-THC), the main psychoactive component of marijuana, is known to dysregu
37 Delta9-tetrahydrocannabinol (THC), the major psychoactive component of marijuana, is toxic for hippoc
38 elta-9-tetrahydrocannabinol (THC), the major psychoactive component of marijuana, suppresses host imm
41 thylenedioxymethamphetamine (MDMA), the main psychoactive component of the recreational drug ecstasy,
44 changes primarily involve an increase of the psychoactive compound (9)-tetrahydrocannabinol (THC) and
47 -9-tetrahydrocannabinol (THC) is the primary psychoactive compound in Cannabis, which is studied exte
51 trahydrocannabinol (THC), the most prominent psychoactive compound of marijuana, plays a crucial regu
52 in detecting the primary and the most sought psychoactive compound tetrahydrocannabinol (THC) in mari
53 ling studies suggest why the closely-related psychoactive compound tetrahydrocannabinol may not have
54 cs oxantel pamoate and pyrantel pamoate; the psychoactive compounds hydroxyzine pamoate (Vistaril) an
56 ts possible role in the in vivo synthesis of psychoactive compounds or neurotoxins and has been chara
57 edict putative therapeutic properties of 428 psychoactive compounds that belong to the phenylethylami
58 of fast-acting antidepressants and possibly psychoactive compounds with effectiveness against other
60 ahydocannabinol (THC+ status), the principal psychoactive constituent in cannabis, was associated wit
64 elta(9)-tetrahydrocannabinol (THC), the main psychoactive constituent of cannabis, affects body weigh
67 -Delta9-tetrahydrocannabinol (THC; the major psychoactive constituent of marijuana), due to enhanced
69 eptor 1 (CB1) is the principal target of the psychoactive constituent of marijuana, the partial agoni
70 ta(9)-tetrahydrocannabinol (Delta(9)-THC), a psychoactive constituent that activates cannabinoid CB(1
71 elta(9)-tetrahydrocannabinol, the main plant psychoactive constituent, activate both cannabinoid rece
72 pairs memory through interaction between its psychoactive constituent, Delta-9-tetrahydrocannabinol (
74 g 1, 1992, and June 30, 1995, and had used a psychoactive drug (tricyclic antidepressant, benzodiazep
76 ctive serotonin-reuptake inhibitor, or other psychoactive drug [mainly major tranquillisers]) between
80 untary consumption of edibles containing the psychoactive drug Delta(9)-tetrahydrocannabinol (THC).
81 te (Ritalin) is the most commonly prescribed psychoactive drug in children for the treatment of atten
82 ormone response to stimuli associated with a psychoactive drug in rats and suggest that the effect is
85 lowered by amphetamine, indicating that the psychoactive drug induced a conditioned reduction in tas
86 report on the antimicrobial activity of the psychoactive drug metergoline, which is specific against
87 domide ([+]-alpha-phthalimidoglutarimide), a psychoactive drug that readily crosses the blood-brain b
92 or dependence was the highest for prescribed psychoactive drugs (hazards ratio, 13.0; 95% confidence
93 d in laboratory animals for almost all other psychoactive drugs abused by humans, as well as for nico
94 ities elicited by a panel of neuroactive and psychoactive drugs administered to a cohort of nearly 70
98 duced neuroadaptations and demonstrates that psychoactive drugs and stress trigger divergent changes
100 ters that are the molecular targets for such psychoactive drugs as cocaine, amphetamines, and therape
101 rce of durable fibers, nutritious seeds, and psychoactive drugs but few economic plants are so poorly
103 neral therapeutic classes into which various psychoactive drugs fall, based on high-content statistic
104 cher (F344) inbred rat strains to stress and psychoactive drugs have been related to differences in t
105 se and abuse of most other licit and illicit psychoactive drugs have been shown to be substantially h
107 can contribute to the regulation of mood by psychoactive drugs in mental illnesses such as bipolar d
110 tem and is a site of action for a variety of psychoactive drugs including antidepressants, amphetamin
111 convincingly provided in vivo evidence that psychoactive drugs increase dopamine (DA) levels in huma
113 on of the cellular and behavioral effects of psychoactive drugs of abuse, we developed Cre/loxP condi
114 Little is known about the acute effects of psychoactive drugs on impulsivity and decision making in
115 ges in mental states such as those caused by psychoactive drugs relies on clinical assessments that a
116 be involved in the regulation of behavior by psychoactive drugs such as antipsychotics and mood stabi
117 is rats show greater behavioral responses to psychoactive drugs than Fischer rats and they fail to sh
118 nicotine, cocaine, or amphetamine, which are psychoactive drugs that induce well-documented neuroadap
119 emission rates of some of the metabolites of psychoactive drugs through WWTP discharges were higher t
120 inquiry through the acute administration of psychoactive drugs to patients with serious mental illne
121 of death were tuberculosis, opioid use, HIV, psychoactive drugs use, viral hepatitis, and obesity, ea
124 metabolic variations, medical comorbidities, psychoactive drugs, alcohol use, mental state) tend to v
125 he determination of common legal and illegal psychoactive drugs, and major metabolites, in breast mil
126 iffer in the initial, reinforcing effects of psychoactive drugs, but not in responses seen after the
127 titute the principal sites of action of many psychoactive drugs, including amphetamines and cocaine,
129 ilieu and is potently inhibited by number of psychoactive drugs, including cocaine, amphetamines, and
130 evious findings with other licit and illicit psychoactive drugs, individual differences in caffeine u
131 KC is a target for the therapeutic action of psychoactive drugs, our findings indicate that the patho
132 fluences of emotionality, thought speed, and psychoactive drugs--and atypical differences in individu
142 r in behavioral and biochemical responses to psychoactive drugs: Lewis rats show greater behavioral r
147 ly consumed behavioral drug caffeine, as the psychoactive effects of caffeine are mediated largely by
149 (decreased) animals, which suggests that the psychoactive effects of cocaine are influenced by the st
150 -steroid hormone estradiol (E2) enhances the psychoactive effects of cocaine, as evidenced by clinica
152 1) cannabinoid receptor mediates many of the psychoactive effects of Delta(9)THC, the principal activ
153 approach, called DISSECTIV, to mitigate the psychoactive effects of fenethylline and show that its r
155 tly neurogenesis by overcoming the undesired psychoactive effects of neuronal CB(1) cannabinoid recep
156 g site for cocaine and other stimulants, the psychoactive effects of which are associated primarily w
157 tween these two metabolites cause Captagon's psychoactive effects to act faster and far more potently
158 ol (CBD), a constituent of cannabis with few psychoactive effects, has been reported in some studies
159 nol, have been studied extensively for their psychoactive effects, it has become apparent that certai
160 DA receptors (NMDARs) may trigger ketamine's psychoactive effects, ketamine or its major metabolite n
161 ral) cannabinoid receptors should be free of psychoactive effects, perhaps allowing for more effectiv
168 e include the conversion of cocaine to a non-psychoactive form, the degradation of nicotine, activati
172 elta(9)-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, are a pressing conc
173 a(9)-tetrahydrocannabinol (THC), the primary psychoactive ingredient in cannabis, are believed to be
174 tetrahydrocannabinol (Delta9-THC), the major psychoactive ingredient in cannabis, causes fetal growth
176 nnabinol (Delta9-THC; 1.19 mg/2 ml), the key psychoactive ingredient in cannabis, in a set of 16 heal
177 elta(9)-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, play major roles in
178 9)-tetrahydrocannabinol (THC), the principal psychoactive ingredient in marijuana, acts as a partial
180 with delta-9-tetrahydrocannabinol (THC), the psychoactive ingredient in marijuana, have been unsucces
181 of Delta9-tetrahydrocannabinol, the primary psychoactive ingredient in marijuana, whereas S1P recept
184 Tetrahydrocannabinol (Delta9-THC), the major psychoactive ingredient in preparations of Cannabis sati
186 used by humans, as well as for nicotine, the psychoactive ingredient in tobacco, these studies would
187 ivated by Delta(9)-tetrahydrocannabinol, the psychoactive ingredient of cannabis, and mediate physiol
188 ound that Delta(9)-tetrahydrocannabinol, the psychoactive ingredient of cannabis, disrupts autophagy
189 tetrahydrocannabinol (delta-9-THC), the main psychoactive ingredient of cannabis, on anxiety and on a
190 elta-9-tetrahydrocannabinol (THC), a primary psychoactive ingredient of marijuana, affects locomotor
195 ein-coupled receptor (GPCR) triggered by the psychoactive ingredients in marijuana, as well as endoge
198 racteristics such as severity, duration, and psychoactive medication do further impact on biological
199 es (r = 0.91, P<.001), quantity of different psychoactive medication dosages 8 hours prior to assessm
201 rformance, cognitive dysfunction, as well as psychoactive medication use are significantly associated
202 tical illness, new psychiatric diagnoses and psychoactive medication use is increased in the months a
203 nder, dementia stage, function, comorbidity, psychoactive medication use) and nesting effects of resi
204 d documented psychiatric history or received psychoactive medication within 30 days before entering t
206 psychiatric illnesses and prescriptions for psychoactive medications in the 5 years before critical
207 enduring effects have been observed for the psychoactive medications, which appear to be largely pal
209 at creates antibodies against heroin and its psychoactive metabolites by presenting multihaptenic str
214 re we report that serotonin differs from the psychoactive N-methyltryptamines by its ability to engag
216 CBD, which alone produced no significant psychoactive or cardiovascular effects, did not signific
218 This study draws upon a nationwide survey of psychoactive pharmaceuticals (i.e., antischizophrenics,
219 spinach accumulation and metabolism of four psychoactive pharmaceuticals found in reclaimed wastewat
220 vity contingent upon the administration of a psychoactive pharmacological agent has been demonstrated
221 provides an opportunity to study the use of psychoactive plants in the past and to better understand
222 of puparial casings; (4) distinguish between psychoactive plants products; and (5) differentiate betw
224 e and show that its rapid-onset and distinct psychoactive properties are facilitated by functional sy
225 d in traditional spiritual practices for its psychoactive properties by the Mazatecs of Oaxaca, Mexic
236 n by the trade name Captagon, is a synthetic psychoactive stimulant that has recently been linked to
238 ot applicable to detect an alarming array of psychoactive stimulants, tranquilizers, and synthetic op
240 rain by chronic exposure to several types of psychoactive stimuli, including drugs of abuse, stress,
241 psychiatric diagnostic categories assessed, psychoactive substance abuse conferred the highest risk
242 dioxy-N-methylcathinone (methylone) is a new psychoactive substance and the beta-keto analog of 3,4-m
243 f genetic and environmental risk factors for psychoactive substance dependence was similar in males a
246 tic factors are important in the etiology of psychoactive substance use (PSU), we know little of how
249 on deficit hyperactivity disorder (ADHD) and psychoactive substance use disorder (alcohol or drug abu
250 rame were highest in people diagnosed with a psychoactive substance use disorder at first discharge (
251 s were more likely to receive a diagnosis of psychoactive substance use disorder but no other psychia
252 he criteria for an anxiety disorder, 60% for psychoactive substance use disorder, 53% for another par
253 he risks in first-degree relatives for ADHD, psychoactive substance use disorder, alcohol dependence,
254 t patients with concurrent schizophrenia and psychoactive substance use disorders may be adequately t
255 aches to prevention and treatment of illicit psychoactive substance use, abuse, and dependence, we ne
256 Cannabis is the most frequently used illicit psychoactive substance worldwide; around one in ten user
260 ion of A(1)AR by caffeine, a widely consumed psychoactive substance, could antagonize the endogenous
265 SCs) continue to be the largest group of new psychoactive substances (NPS) monitored by the European
267 ise the third largest number of reported new psychoactive substances (NPS), according to the United N
268 c cathinones are among the most consumed new psychoactive substances (NPS), but their increasing numb
270 exchange has been used to characterize novel psychoactive substances (NPSs) which are small synthetic
271 ide, cannabis is one of the most widely used psychoactive substances and cannabis use has been implic
273 enetic risk factors for dependence on common psychoactive substances cannot be explained by a single
276 neral physiological and cognitive effects of psychoactive substances or psychopathological conditions
279 ubstances known as "designer drugs," or "new psychoactive substances" (NPS), is increasing at an alar
280 on level use of licit and illicit drugs, new psychoactive substances, human exposure to a wide range
281 amine (DAT) are prominent targets of various psychoactive substances, including competitive inhibitor
284 s are often sufficient for identifying novel psychoactive substances, they may not readily differenti
285 f demographic variables and the use of other psychoactive substances, we found that psychedelic subst
286 bute to dependence on both licit and illicit psychoactive substances, we know little of how these ris
287 mind-altering compounds, also known as "new psychoactive substances," is increasing globally at an a
294 rugs (pragmatically clustered and termed new psychoactive substances; [NPS]) has challenged tradition
295 bogaine and (-)-voacangine are plant derived psychoactives that show promise as treatments for opioid
296 species that converted L-Phe into the potent psychoactive trace amine phenethylamine, which crosses t
299 These findings show that, like several other psychoactive treatments, repeated rTMS sessions can exer
300 cribe how toluene, the most commonly studied psychoactive volatile solvent, alters synaptic transmiss