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1 n open artery, the CONDOR signal was clearly pulsatile.
2 laints of severe abdominal pain and palpable pulsatile abdominal mass located in the left epigastric
3 e hypothalamus, Kiss1(ARH)), which drive the pulsatile activity of gonadotropin-releasing hormone (Gn
7 rial elastance (Ea) represents resistive and pulsatile afterload of the heart derived from the pressu
14 ptible to the deleterious effects of greater pulsatile and early arterial load on diastolic function
17 al afterload-as reflected in blood pressure, pulsatile and resistive load-is associated with adverse
18 ular Fyn activity to be spatially localized, pulsatile and sensitive to adhesion/integrin signaling.
21 exhibit the ability to differentiate between pulsatile and sustained signals in the regulation of dow
24 er function to assess integrated measures of pulsatile aortic load, including arterial compliance, re
26 his study sought to test whether measures of pulsatile arterial function are useful for diagnosing he
28 d models that included SBP, higher total and pulsatile arterial load were associated with increased m
30 al-time recording of hemodynamic parameters [pulsatile arterial pressure (PAP) and heart rate (HR)].
32 of an apical medial actomyosin network whose pulsatile behavior in wild-type embryos drives the apica
33 quantitative understanding of the essential pulsatile behavior of GUVs under hypotonic conditions by
36 occurs simultaneously with rapid changes in pulsatile blood flow, ventricular function, and downstre
38 her as an episodic process, characterized by pulsatile bursts, or as a constitutive process, characte
43 any tissue-scale shape changes are driven by pulsatile contractions of intercellular junctions, which
44 nonmuscle myosin II (NMII) reporter revealed pulsatile contractions of the actomyosin cortex, and inh
47 omotes sexual maturation, which requires the pulsatile, coordinated delivery of gonadotropin-releasin
48 ethods based on PRCs under the assumption of pulsatile coupling to predict the delays that synchroniz
54 cular toxicity may be related to the pH, the pulsatile delivery, or the chemotherapeutic drugs used.
58 es head-up tilt) compared with patients with pulsatile devices (24+/-7 and 35+/-8 bursts/min; P<0.01)
62 1 women (pulsatile devices=78) and 1535 men (pulsatile devices=402) from 89 institutions who were pro
66 polymer Layers (SEAL), and create injectable pulsatile drug-delivery microparticles, pH sensors, and
67 titutional scaling relationships between the pulsatile dynamics and GUV properties over multiple time
76 Taken together, these results suggest that pulsatile dynamics play a pervasive role in yeast and ma
79 turing cardiac cells with the application of pulsatile electrical fields designed to mimic those pres
80 tigation of the sensorimotor interactions in pulsatile electrolocation shows, for the first time, tha
82 hereby facilitates transmission of excessive pulsatile energy into the cerebral microcirculation, lea
83 tolic hypertension, excessive penetration of pulsatile energy into the microvasculature of target org
84 PWV on the transmission of harmful excessive pulsatile energy to the brain is not well-understood.
86 ion, likely due to increased transmission of pulsatile energy to the delicate cerebral microvasculatu
88 f patrolling monocytes in the high shear and pulsatile environment of large arteries in healthy, hype
89 a patterned distribution of basal cells with pulsatile ERK activity, and down-regulation was linked t
90 that respond to EGF with frequency-modulated pulsatile ERK activity, stimulation through a heterologo
96 ranscripts in individual worms, we show that pulsatile expression of the microRNA (miRNA) lin-4 maint
97 nstrate that this insulation is optimal when pulsatile expression of the miRNA and its target is sync
98 in-releasing hormone (GnRH) is secreted in a pulsatile fashion by hypothalamic neurons, and alteratio
100 h condition was performed under constant and pulsatile flow at 60 beats per minute, thus yielding eig
105 nd DT (n = 638) and 114 DT patients with the pulsatile flow HeartMate XVE (Thoratec Corporation).
109 gned to mimic the human heart by producing a pulsatile flow in parallel with the patient's heart, new
113 r in ECs exposed to physiologically relevant pulsatile flow than pathophysiologically relevant oscill
114 ntricular assist devices, the restoration of pulsatile flow through modulations in pump speed leads t
115 ught to determine whether the restoration of pulsatile flow through modulations in pump speed would r
116 tems 1, 2, and 3, flow rate for constant and pulsatile flow was measured, respectively, with biases o
119 ative number of leukocyte TEM as compared to pulsatile flow, whereas passing WSS at peak systole of t
122 icant sex difference in mortality for either pulsatile-flow (P=0.82) or continuous-flow (P=0.95) devi
126 r LVAD implantation compared with men in the pulsatile-flow era (46.9% versus 31.1%, P<0.0001) but no
127 for demographics and risk factors during the pulsatile-flow era (odds ratio, 2.13; 95% CI, 1.45-3.10;
129 quality of life when treated with implanted pulsatile-flow left ventricular assist devices as compar
132 urgency status 1A, 1B, and 2; patients with pulsatile-flow LVADs; and patients with continuous-flow
134 d by atherosclerotic plaque rupture, complex pulsatile flows through stenotic regions producing high
136 crete significant VEGF in response to 5 h of pulsatile fluid shear stress (PFSS; 5 dynes/cm(2) at 1 H
137 ly elastic in order to sustain the basal and pulsatile forces imposed on their walls throughout life.
138 with a Flexcell device, to recapitulate the pulsatile forces induced by congestion, and performed mi
139 of developmental endpoints alone, including pulsatile frequency-modulated signaling associated with
141 with germline loss of the MC4R, we assessed pulsatile GH release and insulin-like growth factor-1 (I
142 1, and Y2 receptor knock-out mice) to assess pulsatile GH secretion under both fed and fasting condit
144 simply based on the GH input signal pattern: pulsatile GH stimulation in males versus near-continuous
145 ular mechanisms by which various patterns of pulsatile GnRH regulate gonadotrope responsiveness remai
146 Our results indicate that the resurgence in pulsatile GnRH release at the termination of the juvenil
147 yed by a neurobiological switch that arrests pulsatile GnRH release during infancy and then triggered
148 ) in governing this postnatal development of pulsatile GnRH release in primates and therefore the tim
150 rons in the brain of the mouse and to reduce pulsatile GnRH secretion in female pubertal monkeys; the
153 was not detected under basal conditions, but pulsatile GnRH stimulated ICER to a greater extent at hi
154 G(q) signaling in response to continuous or pulsatile GnRH using fluorescence resonance energy trans
159 emerged as important in modulating the tonic pulsatile gonadotropin-releasing hormone (GnRH) release.
161 ion of EED from the Kiss1 promoter disrupted pulsatile gonadotropin-releasing hormone release, delaye
167 mination and synchronization responsible for pulsatile hormone release from neuroendocrine cells.
169 itary growth hormone (GH) secretory profiles-pulsatile in males and persistent in females-regulate th
175 intracellular free calcium oscillations and pulsatile insulin release in isolated islets, however a
177 that in T2DM) indicated that the pattern of pulsatile insulin secretion delivered via the portal vei
186 sory feature dependent inputs that mimic the pulsatile-like A1 responses to tones in the ABA- triplet
187 feedback modulation by introducing adaptive pulsatile linear delayed feedback stimulation (apLDF), w
188 t from aDBS and cDBS, we consider continuous pulsatile linear delayed feedback stimulation (cpLDF), s
189 lity than those with high 30-day SBP and low pulsatile load (26.1% versus 8.1%; hazard ratio, 3.62; 9
191 impedance (Z(c)), total arterial compliance (pulsatile load), and systemic vascular resistance index
194 ble effect of the LH harmonic response on RV pulsatile load: the LH harmonic response was responsible
196 s activation of these neurons would generate pulsatile luteinizing hormone (LH) secretion in vivo.
197 ot exhibit the stress-induced suppression in pulsatile luteinizing hormone secretion observed in cont
200 ) and subsequent reconditioning by 90 min of pulsatile machine perfusion (PP) (30/20 mm Hg) or nonpul
202 All kidneys underwent continuous hypothermic pulsatile machine perfusion until transplant: 69 with si
207 Clinical presentation consisted of palpable pulsatile mass, pain, reduced lower limb motion, or visi
208 We achieved this using brief low-amplitude pulsatile mechanical stimuli to selectively activate Pac
209 isolates of Escherichia coli, showing 5 W in pulsatile mode produced the highest signal-to-noise rati
213 ition of planar polarity leads to asymmetric pulsatile Myosin II accumulation in the basal, proximal
217 istinct Msn2 activation dynamics: Msn2 shows pulsatile nuclear activation with dose-dependent frequen
219 how that oncogene expression leads to either pulsatile or sustained ERK activity that correlate with
222 hat this homeostatic challenge confronts all pulsatile organs, we developed a high resolution imaging
223 ing further evidence for the hypothesis that pulsatile output from the ganglia can synchronize islet
224 r assemblage of GnRH1 neurons to produce the pulsatile output necessary for activation of the pituita
225 Three exceptional genes are transcribed in a pulsatile pattern in a variety of CDK-APC/C arrests.
226 tal delivery of insulin in a constant versus pulsatile pattern led to delayed and impaired activation
228 TEMENT Textbooks indicate until now that the pulsatile pattern of growth hormone (GH) secretion is pr
230 f this pathway - cortisol - is secreted in a pulsatile pattern, with changes in pulse amplitude creat
233 Conflicting literature on the benefit of pulsatile perfusion (PP) over cold storage (CS) warrants
234 donated human kidneys undergoing hypothermic pulsatile perfusion deemed unsuitable for transplantatio
235 tion and subjected to static cold storage or pulsatile perfusion with an RM3 pump at 22 degrees C for
237 nt outcome when organs are preserved through pulsatile perfusion; however, the underlying mechanisms
239 cells is oscillatory and are consistent with pulsatile PFK1 being the mediator of slow glycolytic osc
243 For small children, paracorporeal pneumatic pulsatile pumps (e.g., Berlin Heart EXCOR VAD, Berlin He
244 bing dental pain-a prevalent condition whose pulsatile quality is widely regarded a primary sensation
245 net right ventricular afterload by elevating pulsatile, relative to resistive, load and may contribut
247 ectly on hypothalamic centers regulating the pulsatile release of GnRH, or indirectly by circulating
248 ian puberty requires a sustained increase in pulsatile release of gonadotrophin releasing hormone (Gn
249 pon a neuroendocrine circuit that evokes the pulsatile release of gonadotropin hormones (luteinizing
250 regulating vertebrate reproduction requires pulsatile release of gonadotropin-releasing hormone (GnR
252 he mechanisms responsible for generating the pulsatile release of gonadotropins from the pituitary gl
254 ntally using female estrous mice that robust pulsatile release of luteinizing hormone, a proxy for Gn
255 identity of the neuronal network generating pulsatile reproductive hormone secretion remains unprove
257 diverse dynamical firing patterns, including pulsatile responses to behavioral events, LFP-aligned os
261 s inhibitory effect on the GnRH/LH surge and pulsatile secretion is mediated by its receptor in the k
262 pothalamus, followed by proper synthesis and pulsatile secretion of GnRH, functions absent in patient
263 puberty is first detected as an increase in pulsatile secretion of gonadotropin-releasing hormone (G
264 hormonal factors, which ultimately drive the pulsatile secretion of gonadotropin-releasing hormone.
265 rons in the Arc to synchronize and shape the pulsatile secretion of kisspeptin and drive the release
267 hormone (GnRH) pulse generator controls the pulsatile secretion of the gonadotropic hormones LH and
268 esis that progesterone inhibits LH surge and pulsatile secretion via its receptor in the ARC and/or A
269 e for kisspeptin in GnRH neuron firing, GnRH pulsatile secretion, negative feedback by gonadal steroi
271 e islet plays a major role in coordinating a pulsatile secretory response at elevated glucose and sup
274 time polymerase chain reaction revealed that pulsatile shear flow decreased the functional targeting
275 helial cells exposed to the atheroprotective pulsatile shear flow than under atheroprone oscillatory
276 osed to either oscillatory or unidirectional pulsatile shear for 2 days and 3 &7 days in regular and
277 associated oscillatory shear stress (OSS) or pulsatile shear stress (PSS) lead to differential respon
278 -4-carboxamide ribonucleotide, metformin, or pulsatile shear stress induces PARP-1 dissociation from
279 e effect of atheroprone and atheroprotective pulsatile shear stress on endothelial cytoskeleton remod
281 ights regarding the mapping between periodic pulsatile stimulation parameters such as amplitude and f
282 , variable across-ear channel selection, and pulsatile stimulation were simulated using uncorrelated
284 ilizing biodegradable scaffolds, incremental pulsatile stretching, and optimal culture conditions.
287 nals, including glucocorticoid hormones, are pulsatile, the effects of transient stimulation on burst
288 persistent, unilateral, treatment-resistant pulsatile tinnitus caused by a small dural arteriovenous
290 Symptoms can include headaches, visual loss, pulsatile tinnitus, and back and neck pain, but the clin
294 f Saccharomyces cerevisiae, we show that the pulsatile transcription factors Msn2 and Mig1 combinator
296 hough physiological steroid levels are often pulsatile (ultradian), the genomic effects of this pulsa
297 n aortic endothelial cells were subjected to pulsatile undisturbed flow or oscillatory DF containing
298 ell culture chamber with a pump, collapsible pulsatile valve and an adjustable resistance element (he
300 dose, mean injection time, injection method (pulsatile vs. continuous), or concomitant intravitreal m