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1 side the nucleolus and diffuse nucleoplasmic punctates.
2 nuclear periphery in root hairs and that the punctate accumulation of VPY is positively regulated by
3 hemicentin (HIM-4), found between BMs, forms punctate accumulations under the AC and controls BM link
4 the characteristic rod shape and developed a punctate acid-fast staining pattern with carbolfuchsin.
9 s and cytoplasm and showed a filamentous and punctate aggresome-like pattern compared with diffuse cy
11 ting high sensitivity and precision for both punctate and diffuse enrichment regions even in the abse
12 the absence of adenine, and cycling between punctate and diffuse phenotypes could be controlled by a
14 essing furrows in wild-type embryos, becomes punctate and loses its cortical association in the absen
15 The premature brain aging phenotype with punctate and multifocal WMHs was observed in ~70% of you
16 l as pronounced dilation in response to both punctate and prolonged stimulation of the contralateral
20 ver 78 months, 31% (134/439) had evidence of punctate and/or linear traumatic microbleeds on MRI.
21 eristic photoreceptor reflectivity in AOSLO (punctate) and in SD OCT (prominent ellipsoid zone) was o
22 srupt PML nuclear bodies from their normally punctate appearance into heterogeneous filamentous struc
23 eflective spots in IR images corresponded to punctate areas of intense autofluorescence visible in fu
24 proteins redistributed to the membrane in a punctate arrangement when all of the accessory Sec compo
25 In contrast, wild-type HMGCLL1 exhibits a punctate as well as a perinuclear immunostaining pattern
26 ectopically coexpressing ppk transforms this punctate Balboa::GFP expression pattern to the uniform d
27 , CD36 or ICAM-1-binding parasites exhibited punctate binding to a subpopulation of HBMECs and bindin
30 ectosigmoid wall with multiple small rounded punctate calcifications within it, and no other visceral
31 this study, we show that Tim-4 quickly forms punctate caps on contact with apoptotic cells, in contra
34 tion into Gb(3)-positive Vero cells rendered punctate cell surface VT1/VT2 binding uniform and subver
35 e chemotactic receptor K(D) displayed strong punctate centers of uropodial contractile force and stro
36 e with large variations in size and multiple punctate centromere loci exhibiting amplified copy numbe
37 ir C terminus in vivo and is co-localized in punctate clusters of CaV1.2 channels via that interactio
40 E490del remained mostly cytoplasmic, forming punctate co-localisations with LC3, increased mineraliza
41 here the proteins are partially localized to punctate compartments, suggesting that Mtmr2-Mtmr13 may
42 zes Ser5 from plasma membrane to perinuclear punctated compartments and the important role of its Y(3
43 ng from circular (Histoplasma capsulatum) to punctate (Cryptococcus neoformans) to labeling at the bu
53 et membrane-centric manner, progressing from punctate dimples, to the formation of a pinched liposoma
54 membranes of cancer cells, where it adopts a punctate distribution and induces membranolysis and rele
55 YK3 in M. truncatula and found that it has a punctate distribution at the cell periphery consistent w
57 rmly distributed in the nucleocytoplasm to a punctate distribution co-localizing with ZmMC1 and ZmMC2
58 not ZmMC9, are predominantly localized in a punctate distribution in both N. benthamiana and maize (
62 e FLNa-binding domain of HCN1, abolishes the punctate distribution of HCN1 channels in neuronal cell
63 ture, two common organizational themes are a punctate distribution of myosin II and distinct patterns
64 a stimulated PKCiota activation and caused a punctate distribution of pPKCiota in the neurites and cy
65 ted protein 1 light chain 3 (LC3) levels and punctate distribution of the autophagic vesicle-associat
66 in both UL50-S216 and UL53-S19 resulted in a punctate distribution of the NEC in infected cells and a
67 HE also caused PKCbetaII translocation and a punctate distribution pattern in myocytes expressing thi
68 onal GFPPhiRz chimera was shown to exhibit a punctate distribution when coexpressed with Rz1, despite
70 e built a generative approach to modeling of punctate distributions that captures the essential chara
72 e LEs, PS-ASOs and LBPA were co-localized in punctate, dot-like structures, likely intraluminal vesic
73 hagosomes but not autolysosomes (assessed as punctate dual fluorescent mCherry-green fluorescent prot
74 compartment consists of regularly assembled punctate elements that cluster in progressively larger s
76 th corneal findings ranging from superficial punctate epitheliopathy to bilateral corneal melt with s
77 4p and their homologs Ysp1p and Sip3p target punctate ER-PM contact sites distinct from those occupie
85 rgo filled the cytoplasm with a diffuse, non-punctate fluorescence that was partially excluded from t
90 The sensitivity in detecting large focal, punctate focal and vessel segment leakage are 95%, 82% a
91 ents with large focal leak, 10 patients with punctate focal leak, and 5,846 vessel segments from 10 p
92 agnostic imaging allows for visualization of punctate focal mineralization in bone epiphyses during n
93 detect three types of leakage (large focal, punctate focal, and vessel segment leakage) and validate
94 cycle and found that EML4 was distributed as punctate foci along the microtubule lattice in interphas
97 tions, UgtP is sequestered away from FtsZ in punctate foci, and division proceeds unimpeded resulting
100 ft marker protein appeared to associate with punctate Gag fluorescence even in the absence of cell su
102 Cx43 in these connexin-deficient melanomas, punctate gap junction-like plaques were evident at sites
104 ith this antibody revealed high densities of punctate GlyRbeta immunoreactivity at inhibitory synapse
105 eyes with pinpoint leakage on FA (P < .001), punctate hypercyanescence on ICGA (P < .001), and pigmen
106 ous RD was associated with appearance of new punctate hypercyanescent spots on ICGA and leaking point
110 s, including semiautomated quantification of punctate hyperreflective vitreous opacities within 5 fov
111 infants (45 imaging sessions) with right-eye punctate hyperreflective vitreous opacities, the vitreou
116 ally effective dopamine signals encoded by a punctate increase or decrease in dopamine levels provide
117 PBB levels increased in 90% of patients with punctate infarcts (<1.5 mL) and in all patients admitted
118 ndrome (aHR, 3.37; 95% CI, 1.52 to 7.46) and punctate inner choroiditis (aHR, 8.67; 95% CI, 2.83 to 2
119 To examine a large cohort of subjects with punctate inner choroidopathy (PIC) looking at risk facto
120 ocal choroiditis with panuveitis (MFCPU) and punctate inner choroidopathy (PIC)--for differences in c
122 ection of MtENOD8-SP-GFP from the vacuole to punctate intermediates and subsequently to symbiosomes,
124 ection of MtENOD8-SP-GFP from the vacuole to punctate intermediates preceding intracellular rhizobial
125 etrical posterior sub capsular cataract with punctate iridescent opacities in the anterior and poster
127 ht, Schirmer test I, presence of superficial punctate keratopathy (SPK), LG volume, and molecular ana
129 generalized peeling skin, leukonychia, acral punctate keratoses, cheilitis, and knuckle pads, which w
130 8F transgenic mice, which spontaneously form punctate keratotic lesions, scaly plaques, and large tum
132 he majority of bacteria and polar to diffuse punctate labeling with anti-Nsp3 for a minority of bacte
135 ly interacted with p62, whereas ST increased punctate LC3 staining, which was well colocalized with p
140 s of SD can occur, resulting in irreversible punctate lesions in the macula, the region of highest vi
142 and Bruch's membrane on SD-OCT, and 2) hard, punctate lesions that are smaller and undetectable on SD
144 I: 1.2, 61.4 [P = .03], respectively), while punctate lesions were exclusively observed in patients w
149 hagosome clearance, assessed as the ratio of punctate light chain-3 abundance in saline to chloroquin
155 protein accumulation, and the characteristic punctate localization of O-fucosylated proteins suggest
158 mplexes from nuclear sites of replication to punctate loci at the cell periphery that partially coloc
160 orescence microscopy revealed an increase in punctate (lysosomal) LAMP-2A staining that co-localized
161 GEC1-A, and HA-GABARAP were distributed in a punctate manner and co-localized with KOPR-EGFP in the G
162 ification and localization of CBH, even when punctate, may allow opportunity to improve motor and beh
166 ange of temperatures and normal responses to punctate mechanical stimuli, both in the basal state and
168 ases with an unusual pattern of mislocalized punctate MHC II staining and intermediate levels of mRNA
169 tter (in 10 of 11 patients) and (b) multiple punctate microhemorrhages in juxtacortical and callosal
172 proteins, NHX5 and NHX6 are associated with punctate, motile cytosolic vesicles, sensitive to Brefel
178 n remodelling factors and Mediator Complex), punctate nuclear localisation in euchromatic regions and
180 the helicase-primase (H/P) complex exhibited punctate nuclear structures that resemble prereplicative
182 Histone modification profiles can be either punctate or diffuse which makes it difficult to distingu
183 genital skeletal dysplasia, characterized by punctate or dot-like calcium deposits in cartilage obser
185 AAGAB is abrogated by a mutation that causes punctate palmoplantar keratoderma type 1 (PPKP1), a huma
187 The MCC portion was identified as stable punctate patches that correspond to furrows in the plasm
188 s were also clearly distinguishable from the punctate, "patchy" localization patterns of MreB-RFP(SW)
189 MTs localize to the tip of flagella and in a punctate pattern along the length, very similar, but not
190 sides of cardiomyocytes evolves into a clear punctate pattern as Cdh2-EGFP molecules outside the punc
191 lized to the cell poles but formed a similar punctate pattern at the membrane when SecA2 was present.
192 was readily detectable and distributed in a punctate pattern characteristic for inclusion bodies.
193 Rpl1-GFP and Rps2-GFP was also observed in a punctate pattern in chloroplasts of tobacco and Arabidop
195 uble 208 TDP-43 CTF was present in a diffuse punctate pattern in neuronal cytoplasm and dendrites wit
197 stem cells, shows that Stwl is present in a punctate pattern in the nucleus that partially overlaps
198 classical latency-associated transcripts, a punctate pattern of LANA expression, and episomal mainte
199 Initially, PrP(Sc) deposits had a small punctate pattern on the edge of muscle cells that coloca
200 ctopic expression displayed a characteristic punctate pattern on the endoplasmic reticulum (ER).
202 requires caspase 6, which is activated in a punctate pattern that parallels the pattern of axonal fr
204 s of new and old cell division as well as in punctate patterns along the long axis of rod-shaped baci
205 ny interpretations in the literature of such punctate patterns as helices should therefore be reconsi
206 stratified based on 'linear' streak-like or 'punctate' petechial-appearing traumatic microbleeds.
207 on of CiaI-GFP in epithelial cells yielded a punctate phenotype not observed with the other C. jejuni
209 h mCherry-tagged FLOTILLIN4 (FLOT4), another punctate plasma membrane-associated protein required for
210 tation as a function of the frequency of the punctate pneumatic stimulus trains and stimulus site (gl
213 omotor nucleus, CR was specifically found in punctate profiles contacting superior rectus and inferio
214 a system that provides automated analysis of punctate protein patterns in microscope images, includin
215 luence the formation of stress granules, the punctate protein-RNA assemblies that form during stress.
217 vir or infection with a UL97 mutant led to a punctate rather than a continuous distribution of the NE
218 landscape of Drosophila may differ from the punctate recombination pattern observed in many mammals
219 oper trafficking of STING to perinuclear and punctated region, known to be important for its activati
220 lysis of the retina and optic nerve revealed punctate regions of reduced cellularity in the ganglion
221 strated a symmetric leukoencephalopathy with punctate regions of restricted diffusion, typical of ALS
222 Furthermore, we observed cGAS localized in punctate regions on the cytosolic side of the chlamydial
223 features such as multifocal, coarse, raised, punctate, round to oval epithelial lesions in the cornea
224 also alters SG formation, whereby only small punctate SG-like bodies that we term RNase L-dependent b
226 atum, Ca(2+)-dependent reduction of the CYAM punctate signal was induced by depolarization or action
227 atients had the characteristic disseminated, punctate, slightly elevated, white epithelial lesions.
228 Annexin A2 colocalized with several LANA-1 punctate spots in KSHV+ body cavity B-cell lymphoma (BCB
229 During latency, LANA localizes to discrete punctate spots in the nucleus, where it tethers viral ep
230 y a shift in intracellular distribution from punctate spots to diffused cytoplasmic staining at a pep
236 t not in normal controls, LC3 and p62 showed punctate staining characteristic of autophagosome buildu
238 demonstrated a distinct increase in antibody punctate staining in the endothelium and Descemet membra
239 th in-situ hybridization also coincides with punctate staining observed in brain, SEG, thoracic, and
243 ng in the endothelium and Descemet membrane; punctate staining was absent from both normal corneas an
244 he receptor's protein, we observed extensive punctate staining within the neuropil and on the membran
247 ortices of male and female mice to discrete, punctate stimuli delivered at a wide range of fixed and
249 , TRIM12c is expressed in the cytoplasm as a punctate structure and induced upon IFN and pathogen sti
250 n regulatory light chain, localizes to small punctate structures and does not colocalize with large,
253 sion levels recruits Dnm1 into mitochondrial punctate structures but fails to support normal fission.
256 hat ubiquilin 1 localizes TREX1 to cytosolic punctate structures dependent upon the TREX1 CTR and lys
258 saspora cells, CoSrc1 and CoSrc2 localize to punctate structures in filopodia that may represent prim
259 ypothesis that SV40 induces the formation of punctate structures in the ER membrane, called foci, tha
260 uria aurantia lectin (AAL) binds to numerous punctate structures in the nuclei of tachyzoites, bradyz
261 elta40p53 is mainly localized to cytoplasmic punctate structures of EC cells, resembling solid-phase
262 CDCP1 relocates from cell-cell junctions to punctate structures on filopodia after activation of EGF
263 1 family of tethering proteins, localizes to punctate structures on opposing surfaces of mitochondria
266 rapid and transient recruitment of NEMO into punctate structures that are anchored at the cell periph
267 oughout the entire cell membrane, aside from punctate structures that may correspond to regions of me
268 doplasmic reticulum (ER) and trafficked into punctate structures that were mutually exclusive with RV
271 molecule 1 (STIM1) triggers SOCE by forming punctate structures with the Ca2+ channel Orai1 and the
273 eceptor kinase-1 (GRK1) accumulated on large punctate structures within the inner segment in ARL3-Q71
275 characterized as being primarily located in punctate structures, but their images had all been annot
276 apical membrane, and redistributes to dense punctate structures, containing WNK1, within the cytopla
281 , but persistent events uniquely generated a punctate surface distribution over a 10 s interval.
283 in ATP2C1 KO cells demonstrate dispersed and punctate trafficking distinct from the perinuclear, tran
284 hIP-seq data but also effective in analyzing punctate transcription factor ChIP datasets, making it w
285 oot apical meristem identified a novel gene, PUNCTATE VASCULAR EXPRESSION1 (PVE1), that is down-regul
286 moglobin (P = 0.0002) and the development of punctate vascular lesions on the colonic surface, which
289 a redistribution of LC3 from the cytosol to punctate vesicles indicative of authentic autophagosomes
290 gy as defined by an increase in LC3-positive punctate vesicles, double-membrane vacuoles, and decreas
292 itions (300 mOsm), human CLN3 was found in a punctate vesicular pattern surrounding the nucleus with
293 metabolism, are altered in association with punctate white matter lesions and "diffuse excessive hig
295 In a high proportion of infants, MRI detects punctate white matter lesions that are not seen on ultra
297 I from that predicted by the model to detect punctate white matter lesions with very good accuracy (a
299 tamate excitotoxicity in the pathogenesis of punctate white matter lesions, but not necessarily in DE