ライフサイエンスコーパス: putatively

1 lymerase found in the apicoplast (apPOL) was putatively acquired through horizontal gene transfer fro

2 We also explored lincRNAs that putatively act upstream of neuroblastoma driver genes, e

3 ein elements, including the acquisition of a putatively active enzyme, give the mitoribosome a distin

4 se of the human genome, GRCh38, contains 146 putatively active L1 elements or full length intact L1 e

5 th sequences of LINE-1 transposons including putatively active L1s.

6 ranging from somatic evolution in cancer to putatively adaptive germline evolution across species.

7 y recent time scale allowed us to search for putatively adaptive loci based on genetic variation.

8 vironment association analyses identified 16 putatively adaptive loci related mainly to biotic and ab

9 However, whether these putatively adaptive shifts in allele frequencies transla

10 tation appeared to be related, in part, to a putatively advantageous allele for the peroxisome prolif

11 s of dissociation in terms of phenotypes and putatively affected neural circuitry.

12 tion with AD+P and include SNPs affecting or putatively affecting risk for schizophrenia and AD.

13 Importantly, also putatively alloreactive single KIR(+) NK cells were elim

14 One such effector may be GPR89, putatively an ion channel or G protein-coupled receptor

15 he implications of this hypothesis for other putatively ancient molybdopterin-based enzymes.

16 in in non-repetitive proteins, including the putatively ancient ribosomal protein S20 (RPS20), which

17 S(E) approach, 1251 different compounds were putatively annotated across 16 samples with 210 classifi

18 We also putatively annotated and mapped the subcellular localiza

19 ists often deal with a significant amount of putatively annotated metabolites.

20 issue sections, the distributions of over 80 putatively annotated molecular species are determined wi

21 Discriminatory compounds were defined and putatively annotated.

22 eparation among genotypes were identified or putatively annotated.

23 y, we quantified prevalence and abundance of putatively anti-Bd bacteria to determine if Bd-inhibitor

24 We detected 11 putatively anti-Bd bacterial OTUs that were present on 9

25 th mutations in genes encoding proteins that putatively are involved in hedgehog (Hh) signaling.

26 HGT from various bacteria, of which only 25% putatively arose through EGT from the chromatophore geno

27 Mendelian randomisation framework identified putatively associated genes at 70 risk signals underlyin

28 This allergen, with putatively associated lipid(s), triggered the production

29 genes evolving under positive selection and putatively associated with a marine phenotype.

30 Donor-specific antibodies (DSA) are putatively associated with a worse prognosis for recipie

31 Taxa putatively associated with chemoautotrophic sulfur oxida

32 FREM3, SDC1, DDC, and LOC727982 genes to be putatively associated with differential susceptibility t

33 nriched in parasites, and expresses proteins putatively associated with parasitism and pathogenesis,

34 o acyl carrier protein (ACP) reductase (BKR) putatively associated with polyketide fatty acid starter

35 cinogenesis and metabolic processes that are putatively associated with risk and prognosis of breast

36 c circuitries in five groups of older adults putatively at-risk for developing dementia- remitted dep

37 by codon optimization and truncation of the putatively autoregulatory N terminus of TMEM165.

38 ction to the statistical quantities they are putatively based on.

39 as an assortment of novel regions that have putatively been under selection in chickens.

40 ility to discriminate between pathogenic and putatively benign missense variants.

41 inatory ability using disease-associated and putatively benign variants from published studies (in bo

42 from Human Gene Mutation Database and 10 002 putatively 'benign' non-synonymous SNVs from UCSC.

43 Furthermore, assessment of putatively biased ligands has been confounded by several

44 ogies, we identified 45 small molecules that putatively bind C3b near ligand-guided functional hot sp

45 eal significant variation in the position of putatively bound Mg(2+).

46 signals is linked to urges to move the body, putatively by engendering noisier sensory input into mot

47 en the "immunity" of disgust to habituation, putatively by reducing gastric dysrhythmias during incen

48 ubstitution in the MEF8 protein replaced the putatively catalytic glutamate of the HXE motif in the D

49 al variants, with nine of these being highly putatively causal and mapping to CYP2A6, MAP3K10, ADCK4,

50 MR analysis revealed 8 putatively causal associations for 6 CpGs with 4 cardiov

51 ascular disease (CVD) traits, we identify 92 putatively causal CpGs for CVD traits by Mendelian rando

52 arent-offspring trios have reported multiple putatively causal genes.

53 signals in regulatory regions) to determine putatively causal genes.

54 ments targeting genes encoding proteins with putatively causal platelet effects in megakaryocyte clon

55 sthma association signals was performed, and putatively causal polymorphisms were characterized in vi

56 Mendelian randomization identified 4 putatively causal proteins for MPV and 4 for PLT.

57 arlier findings that cognitive deficit has a putatively causal role in schizophrenia.

58 Together the 14 putatively causal SNPs explained ~38% of NMR variation,

59 We also identified a putatively causal variant on chromosome 4 mapping to TMP

60 ions can have a critical role in identifying putatively causal variants for a disease or trait among

61 R to fine-map these loci and narrow down the putatively causal variants to 99% credible sets.

62 Fine-mapping of chromosome 19 revealed 13 putatively causal variants, with nine of these being hig

63 e and we estimate that 58% of these SNPs are putatively causal.

64 th intragenic low-frequency variants reveals putatively causative genes in restless legs syndrome.

65 To identify putatively causative genes, we searched for highly signi

66 ntify historical sequence substitutions that putatively caused Aurora kinases to evolve allosteric re

67 devastating citrus disease worldwide that is putatively caused by Candidatus Liberibacter asiaticus a

68 ectual disability and conclude that variants putatively causing haploinsufficiency lead to macrocepha

69 aft genome sequence of R. albus 8, seventeen putatively cellulolytic genes were identified.

70 o assess the pathogenicity and penetrance of putatively clinically important rare variants.

71 lassify as high quality 1,244 of 4,585 (27%) putatively clinically relevant rare (MAF < 1%) variants

72 tifs allowed the identification of two genes putatively coding for branching sucrases in the genome o

73 al copepod Tigriopus californicus to disrupt putatively coevolved mitonuclear genotypes in reciprocal

74 om generation to generation via plant seeds, putatively compose highly adapted species and may have p

75 lagellates share a large array of genes that putatively confer mixotrophy and the ability to use N vi

76 cognitive function, and energy consumption, putatively consistent with diurnal activity, well-develo

77 Two putatively conspecific Symbiodinium strains (both ITS2-t

78 oft tissue comprising blood vessels that are putatively contained within the canal structures does no

79 e onset of germination and resides in dimers putatively containing two isoforms, AXAH1 and AXAH2.

80 rogenic transmission of amyloid beta through putatively contaminated neurosurgical equipment.

81 subset of these isolates identified 94 genes putatively contributing to AMR, including seven class A

82 own adipose tissue (BAT) in skeletal muscle, putatively contributing to protection from the diet-indu

83 We have also identified RNA binding proteins putatively correlated with circRNA biogenesis.

84 In all, 1723 locus pairs are identified as putatively corresponding to a selective sweep or epistat

85 death ligand 1 expression, accompanied by a putatively counter regulatory STAT1(S727) phosphorylatio

86 Three putatively covalent mGlu(2) PAMs were designed and synth

87 ially, we found that the medial part of PMC, putatively covering the supplementary motor area, plays

88 nd we find that, of four conserved cysteines putatively critical for function, only three are absolut

89 s because a control experiment regarding the putatively critical role of guanine bases in the most wi

90 autism spectrum disorder who carry rare and putatively damaging changes in RERE.

91 Effect Analyzer) identified 23 nsSNPs to be putatively damaging/deleterious in at least one of the t

92 fant mortality and increased homozygosity of putatively deleterious alleles in inbred individuals.

93 Putatively deleterious variants explain roughly one-half

94 ermline development to keep the frequency of putatively deleterious variants from rising.

95 ll, these results suggest that incorporating putatively deleterious variants into genomic models slig

96 The contribution of putatively deleterious variants to phenotypic diversity

97 Annual crops accumulate putatively deleterious variants, in part due to strong d

98 that ~33% of nonsynonymous substitutions are putatively deleterious.

99 Vesicles are putatively delivered to the division plane by transport

100 Where we perceive a touch putatively depends on topographic maps that code the tou

101 In TAO, CD34(+) fibrocytes, putatively derived from bone marrow, can be identified i

102 independently the two component subgenomes (putatively deriving from C. canephora and C. eugenioides

103 acquisition method and to quantitate the 29 putatively detected drugs.

104 ed a subset of five individuals who had been putatively diagnosed with "DA2A with severe neurological

105 Only seven genes were putatively differentially expressed, and another two gen

106 pathway analyses were done on lists of genes putatively disrupted by L1s in PDS and controls.

107 0A9's highly conserved cation efflux domain, putatively disrupting its transmembrane helix structure.

108 2017), we estimate bounds on the density of putatively DNA loop-extruding cohesin complexes and CTCF

109 ) of cognitive effort is encoded in the same putatively domain-general brain valuation network implic

110 Nonetheless, putatively dosage balance-sensitive gene groups (Gene On

111 nd more coordinated dosage responses than do putatively dosage-insensitive gene groups, suggesting th

112 ression responses to recent WGD, relative to putatively dosage-insensitive networks.

113 abolic pathways and gene ontologies that are putatively dosage-sensitive based on duplication history

114 irect anatomical connections, but high FC is putatively driven by a top-down cortical control.

115 nship between obesity and metabolic pathways putatively driving hepatic steatosis compared with chang

116 how they differ in size and gene inventory, putatively due to population size variation.

117 ally annotated as "fruA" and renamed "bepA," putatively encoding a carbohydrate phosphotransferase sy

118 n levels of known and novel candidate genes (putatively encoding beta-ketoacyl-(acyl-carrier-protein)

119 sed unannotated and read-through transcripts putatively encoding fusion genes.

120 ic genes) and plant defense (including genes putatively encoding NB-ARC and leucine-rich repeat seque

121 Genes putatively encoding oxylipin metabolic proteins, subtili

122 lly regulated (ASM or mQTL) and 14% as being putatively epigenetically regulated.

123 litate fusion triggering and pore evolution, putatively establishing a favorable membrane configurati

124 d in motoneurons, and the Thy1, expressed in putatively excitatory neurons.

125 ow that all known LNBA strains form a single putatively extinct clade in the Y. pestis phylogeny.

126 y regular-spiking cells) and one inhibitory (putatively fast-spiking cells).

127 and optogenetic manipulations, we show that putatively feedback neurons in layer 5 (hereafter "L5 fe

128 the pride level, with decisions representing putatively fitness-enhancing strategies.

129 which apparently makes them more stable than putatively formed antiparallel L18W-PGLa and MG2a homodi

130 H](-) equivalent to C(64)H(104)O(33) and the putatively found active metabolite at m/z 1283.58 [M + f

131 286 full-length/putatively full-length pneumococcal prophages were ident

132 RNAs that are tightly bound to chromatin and putatively function to locally cis-activate gene transcr

133 rope these alleles are enriched in genic and putatively functional alleles to an extent only compatib

134 We review methods for assaying putatively functional genetic variants and regions, emph

135 s analyzed, we prioritized approximately 100 putatively functional ones located in neuronal OCRs, inc

136 ective of this study was to investigate five putatively functional variants of the norepinephrine tra

137 H2 zinc finger protein with EAR motifs which putatively functions as a transcriptional repressor.

138 ates transcriptional regulation of sltB and, putatively, genes required for tolerance to cation stres

139 work users that likely employ the network in putatively good or bad ways.

140 effect was cooperatively mediated by various putatively HIF-1alpha-dependent mechanisms, comprising a

141 These cases were selected from putatively high-risk families that had three or more sib

142 in object memory, but rodent studies on the putatively homologous lateral entorhinal cortex suggest

143 The same complement of putatively homologous nuclei were identified in both spe

144 Compared with putatively hydrated patients, clinically dehydrated pati

145 LOBSTAHS putatively identified 1969 unique parent compounds in 21

146 earch against human metabolome libraries, we putatively identified an additional 2411 metabolites.

147 ificant LC metabolites, among which two were putatively identified as caffeoylquinic acid methyl este

148 taneous determination of twenty metabolites, putatively identified as carbohydrates, flavonoids, and

149 irs, 2304 pairs (75%) could be positively or putatively identified based on metabolome database searc

150 monoterpenyl glycosides, including nine new putatively identified compounds, were analyzed by UHPLC-

151 Several individual compounds putatively identified in wood samples showed statistical

152 Putatively identified markers were evaluated applying RO

153 Finally, we putatively identified other, previously unreported group

154 Twenty-five compounds were putatively identified, and the main compounds were pheno

155 hanged upon processing, of which 18 could be putatively identified.

156 istically between groups were determined and putatively identified.

157 re 18,640 adipose-derived features; 520 were putatively identified.

158 The regulation is putatively impaired by cardiomyopathy-causing mutations

159 -103/miR-107 within the isoforms HTR4b/i and putatively impairs HTR4 expression.

160 LN-LN synaptic connections putatively implement a bistable gain control mechanism t

161 neuropathological data identified 199 genes putatively implicated in neurodevelopment, synaptic sign

162 network analysis retrieved miRNA-146a as one putatively important regulator of pneumococci-induced ho

163 oducing lipids with structural elements that putatively improve membrane integrity compared to lipids

164 evolutionary preserved function of the DMN, putatively improving translational relevance of preclini

165 om populations of the Eastern Italian Alps - putatively in genetic continuity with the Tyrolean Icema

166 vanced POAG in the EN04 locus was identified putatively in persons of AD.

167 ausal variant disrupt a silencer element and putatively increase ESR1 and RMND1 expression.

168 lassic proposals where cognitive systems are putatively independent, H&M's two-system hypothesis shou

169 ore sensitive to differences in myelination (putatively indexed by the [quantitative] longitudinal re

170 es (CREBBP, WDR24, ARL8A, PHLDA3, LAD1) that putatively influence quantitative variation in red-brown

171 gionally restricted runaway duplications and putatively introgressed variants from archaic hominins.

172 as observed in DNA polymorphism of two genes putatively involved in adaptation to serpentine environm

173 ant feeding, we identify families of enzymes putatively involved in beetle-plant interactions that un

174 other species, a number of protein sequences putatively involved in chemosensory reception were ident

175 est this hypothesis, the expression of genes putatively involved in determination of drupe tissues id

176 cted to improve OT deposition in nasal areas putatively involved in direct nose-to-brain transport) t

177 folded structure, two of the three tyrosines putatively involved in electron transfer, Y345 and Y347,

178 PWE motifs in its C-terminal domain that are putatively involved in G-protein regulation.

179 e exchange factors for Rac and Cdc42 that is putatively involved in GPR124-dependent angiogenic respo

180 ient-rich artificial diet, to identify genes putatively involved in host plant utilization.

181 the stria terminalis (dlBST) as a structure putatively involved in L-3,4-dihydroxyphenylalanine (L-D

182 A systematic search of brain nuclei putatively involved in L-3,4-dihydroxyphenylalanine (L-D

183 cognize external stimuli, including proteins putatively involved in leucine-rich repeat recognition a

184 We identified candidate genes putatively involved in long-day pre-adaptation, and show

185 ngly, three 56 kDa selenium-binding proteins putatively involved in peroxide reduction from gammaprot

186 oding genes and conserved non-coding regions putatively involved in replication and/or expression.

187 sis also identified members of gene families putatively involved in secondary modifications in late b

188 The right Anterior Temporal Lobe (rATL), putatively involved in semantic integration, is distinct

189 aims to provide methods to characterize UGTs putatively involved in SVglys biosynthesis.

190 lycoprotein is a lymphocyte surface receptor putatively involved in T cell development and activation

191 ing to the identification of candidate genes putatively involved in the biosynthesis, pathway regulat

192 Serotonin and dopamine are putatively involved in the etiology and treatment of anx

193 on analyses focused on a set of target genes putatively involved in the plant response to drought, an

194 social feedback was evoked in brain regions putatively involved in theory of mind (temporoparietal j

195 ially expressed, we identified around 250 as putatively involved in virulence and survival-related me

196 t (cells), and in contrast to a modern type, putatively just a very thin crystalline cone.

197 Putatively, KAR activates the receptor KARRIKIN INSENSIT

198 Moreover, flies putatively lacking all sweet taste show little preferenc

199 ir) terminals overlapped with projections of putatively light-sensitive interneurons from the ipsi- a

200 output of mass spectrometry metabolomics to putatively link features on their relation to other feat

201 r-life all-cause mortality risk or mortality putatively linked to chronic inflammation.

202 exhibit hexadirectional modulation, which is putatively linked to grid cell activity.

203 ferences found in surveys of other behaviors putatively linked to ipRGC function (chronotype, seasona

204 unique properties of free-OH groups on ice, putatively linked to the high catalytic activities of ic

205 nt locus in African taurine cattle, which is putatively linked to trypanotolerance and present in cro

206 atively pelagic-dwelling morph and a robust, putatively littoral-dwelling generalist morph, over an a

207 , we identified 26 female-specific RAD loci, putatively located on the W chromosome, as well as 148 s

208 Though both tasks and surveys putatively measure self-regulation, they show little emp

209 tissue to evaluate whether targeted proteins putatively mediate the effects of genetic variants on se

210 We examined two geochemically divergent but putatively methanogenic regions of Yellowstone National

211 k can account for the full range of observed putatively model-based behaviors while still utilizing a

212 demonstrations linking striatal dopamine to putatively model-free learning did not rule out model-ba

213 uracy) were recorded for 8,957 out of 12,080 putatively monoisotopic features of the LC-MS data set.

214 gest the need to include nuclear motion in a putatively more complete model.

215 cable and not diminished by the use of other putatively more invasive procedures that are frequently

216 owever, there is broad potential to mitigate putatively negative impacts to seasonal migrants during

217 concussed athletes with lower levels of the putatively neuroprotective KYNA/QUIN ratio reported sign

218 World Monkeys (NWMs), and apes, focusing on putatively neutral autosomal sites and controlling for p

219 recent SwissVar disease variants and 123,935 putatively neutral exome sequencing variants and 0.027-0

220 we analyzed data sets of disease-causing and putatively neutral human variants mapped to protein 3D s

221 targeted gene capture to sequence over 2,000 putatively neutral regions for both species.

222 Diversity at putatively neutral sites is negatively correlated with t

223 th, and morphological characteristics of the putatively new Botrytis species were also assessed to pr

224 tion of behavior, local neural activity, and putatively non-neural processes.

225 These were co-expressed with putatively non-resistant form in all developmental stage

226 nd precision, occasional antisense loci, and putatively noncanonical loci.

227 we tested the pre-registered hypothesis that putatively noradrenergic (NA)-dependent functions would

228 and Bayesian networks implied that the taxa putatively not capable of extracellular electron transfe

229 t an aggressive fungal keratitis caused by a putatively novel species of Lophotrichus in a patient wi

230 work to identify kaempferol and esculetin as putatively novel therapies for IF/TA and provided experi

231 cleotide polymorphisms on chromosome 20 (and putatively on the THBD gene for thrombomodulin) that inc

232 entration below K(d), CorA adopts a dynamic (putatively open) state of multiple conformations that im

233 veral risk-genes including NRXN2 and CNTNAP2 putatively overlay maternally inherited loss-of-function

234 A putatively parallel population of IL-17A(+)Vgamma9(+)Vde

235 t Acropora millepora colonies (genotypes) to putatively pathogenic bacteria (Vibrio spp.).

236 acial features seen in individuals harboring putatively pathogenic BICRA variants.

237 The putatively pathogenic brain somatic mutations identified

238 In an unselected population, the putatively pathogenic genetic variants were not associat

239 About half of patients with sarcoma have putatively pathogenic monogenic and polygenic variation

240 for identifying and functionally validating putatively pathogenic variants from next generation sequ

241 s for identification and validation of novel putatively pathogenic variation in these regions.

242 arr (Salvelinus alpinus) phenotypes, a slim, putatively pelagic-dwelling morph and a robust, putative

243 e that, rather than identifying and removing putatively phylogenetically uninformative sites, instead

244 pp. field isolates and amplified a subset of putatively phytopathogenic P. syringae in a manner causa

245 al secreted proteomes, indicating that fungi putatively play a minimal but specialized role in subsea

246 tivation suggests that all three ER subtypes putatively play a role in up-regulation of VTG.

247 These putatively positively selected SV hotspots are enriched

248 olar decoy groups into the pocket to capture putatively present water molecules could not collect any

249 P = .05) gray matter volumes relative to the putatively preserved group (ES = 0.91-1.10).

250 severely deteriorated group relative to the putatively preserved group (F2,82 = 13.8, P < .001, effe

251 Cluster analyses revealed 25 putatively preserved patients (26%), 33 moderately deter

252 machanna has several characters that exhibit putatively primitive conditions not encountered in the f

253 The reaction putatively proceeds through a Cp*Ir(III)-pai-allyl inter

254 y presents the identification of rice traits putatively producing the largest yield benefits in five

255 tral amygdala somatostatin-positive neurons, putatively projecting to the PAG, which-similarly to the

256 Prevalence of putatively protective antibodies among vaccine-eligible

257 We found that gene-disruptive and putatively protein-damaging URVs (but not synonymous URV

258 reduction in the levels of circulating cells putatively provided with vasculoregenerative properties

259 A phenomenon called "sustained quenching" putatively provides photoprotection and enables their su

260 corporated into SELEX selection protocols to putatively reduce the propagation of byproducts and avoi

261 ctivation and dysfunctional reward learning, putatively reflecting decreased dopaminergic signaling.

262 al layer-4 cell populations: one excitatory (putatively regular-spiking cells) and one inhibitory (pu

263 In particular, 121 DEmiRs putatively regulated a total of 237 DEGs involved in glu

264 Genes putatively regulated by CGI-associated enhancers are enr

265 ssed in memory compared with naive cells and putatively regulated by DNA methylation.

266 One of the phosphosites putatively regulated by HAI1 was S313/S314 of AT-Hook-Li

267 bud tissue, we identify the genetic pathways putatively regulated by TB1.

268 n multiple cancer signaling pathways through putatively regulating their target genes, including clin

269 ase-associated variants, although located in putatively regulatory regions, do not have detectable ef

270 bout probabilistically aberrant events, thus putatively rendering these events less surprising.

271 5-HT1BRs putatively represent a molecular target for development

272 infected with MTB dendritic cells (DCs) from putatively resistant individuals diagnosed with latent T

273 PKMzeta recently emerged as a molecule putatively responsible for maintaining encoded memories

274 even phytopathogen-enriched protein families putatively secreted by type II secretory system: PheA (C

275 The remaining putatively secreted proteins shared highest sequence sim

276 ight into the functional significance of the putatively selected amino acid polymorphisms.

277 Genomic regions putatively selected during modern temperate maize breedi

278 and six crucial environmental variables, 16 putatively selected loci showed significant correlation

279 ch to nearly 10,000 fMRI studies to identify putatively separable regions of MFC and determine which

280 the O5' leaving group suggests that G32 may putatively serve as the general acid.

281 function, likely through Rho1 signaling and putatively serving as a link between the secretion machi

282 ing p-value-based tests, some of which being putatively shared in response to pea (pathotype I and II

283 ied novel repeat RNAs, miRNA-sized RNAs, and putatively structured intron RNAs of potential biologica

284 a rigorous approach to the inference of SVs putatively subject to selection in tumors.

285 underscored by their pleiotropic capacities, putatively targeting multiple pathways within a single n

286 uggests a role as transcriptional repressor, putatively targeting pathways involved in cell prolifera

287 dopsis (Arabidopsis thaliana) miR858a, which putatively targets R2R3-MYB transcription factors involv

288 pted by a reminder-extinction procedure that putatively targets reconsolidation.

289 Interestingly, TB1 also putatively targets several other domestication loci, inc

290 Decisions reflecting elastic demand, putatively the most effortful decisions, elicited greate

291 construction, this mapping must be learned, putatively through changes in the effective connectivity

292 data show that the QTL regions contain genes putatively under selection.

293 deficits and altered long-range connectivity putatively underlie Multisensory Integration (MSI) defic

294 for the neurophysiological adaptability that putatively underlies self-controlled behavior.

295 g of NTTB isolates revealed varied mutations putatively underlying their lack of toxin production, as

296 s can identify quantitative trait loci (QTL) putatively underlying traits of interest, and nested ass

297 Moreover, the perceptual construction of putatively 'unitary' auditory events requires more than

298 stigating PKMzeta, however, have used either putatively unselective inhibitors or conventional knock-

299 "Leader" males with harems putatively use loud calls to deter challenges from non-r

300 or that influences cellular hypoxia sensing, putatively via an action on the hypoxia-inducible factor