ライフサイエンスコーパス: pyridyl

1 aphenylporphyrin dianion), and S = 1/2 4-(4'-pyridyl)-1,2,3,5-dithiadiazolyl (py-DTDA) radical, 2.

2 [Co4(bptz)4(dbm)4].4MeCN (2) (bptz = 3,6-bis(pyridyl)-1,2,4,5-tetrazine; dbm = 1,3-diphenyl-1,3-propa

3 templated metallacycles with bptz [3,6-bis(2-pyridyl)-1,2,4,5-tetrazine] in high yields.

4 for the accessory ACh site, such as 3-[3-(3-pyridyl)-1,2,4-oxadiazol-5-yl]benzonitrile (NS9283), can

5 cid and subsequently reacted to 2,4,6-tri(2'-pyridyl)-1,3,5-triazine (TPTZ) then measured at 593 nm.

6 90 degrees Pt(II) acceptor with 2,4,6-tris(4-pyridyl)-1,3,5-triazine (TPyT) or 5,10,15,20-Tetra(4-pyr

7 ially the one using C3-symmetric 2,4,6-tri(4-pyridyl)-1,3,5-triazine as pore-partition agent in MIL-8

8 nd measured urine 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanol (a biomarker of cigarette smoke expo

9 ) (0.05 ng/L) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) (0.2 ng/L) along with the redu

10 utanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) as the targets, we first devel

11 ent nicotine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a metabolite of the powerful

12 tanone (NNK), and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), NNAL-N-beta-glucuronide, and

13 novel biomarker [4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL)], an established biomarker (co

14 ogenic metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol [NNAL]) and VOCs (including metabolit

15 nicotine uptake; 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and its glucuronides (total NNAL), a

16 lness, smokers by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol had similar severity of lung injury a

17 to patients with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol levels consistent with active smoking

18 Patients with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol levels in the active smoking range we

19 Urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol levels were consistent with active sm

20 with undetectable 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol levels.

21 red by history or 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol was not associated with acute respira

22 measured by urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol was significantly associated with acu

23 ine, and the TSNA 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol were identified and quantified in aut

24 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, a validated tobacco-specific marker,

25 with undetectable 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.

26 the formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) (0.05 ng/L) and 4-(methylnitro

27 on TSNAs, including (methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3

28 ific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N'-nitrosonornicotine (NNN

29 ific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N-nitrosonicotine (NNN) ar

30 ecific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces Ca(2+) signalling, a m

31 ornicotine (NNN), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), and 4-(methylnitrosamino)-1-(

32 dducts of the NOC 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), O(6)-methyl-dG (O(6)-Me-dG) a

33 obacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), the inflammatory agent lipopo

34 l lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

35 cific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

36 obacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK); and r-1-,t-2,3,c-4-tetrahydro

37 ing agent, 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone (NNKOAc).

38 trosonornicotine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, and volatiles.

39 alogs in blocking 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced short-term O(6)-methylguanin

40 arcinogens [e.g., 4-[methylnitrosamino]-1-(3-pyridyl)-1-butanone].

41 1-Alkyl-1H-imidazol-2-yl, ortho pyridyl, 1-alkyl-1H-benzo[d]imidazole-2-yl, 4-bromo-1-me

42 escence spectra of a series of 5-substituted pyridyl-1,2,3-triazolato Pt(II) homoleptic complexes sho

43 ficantly inhibited the formation of alpha-(4-pyridyl-1-oxide)-N-t-butylnitrone (4-POBN)-1-hydroxyethy

44 Ph(CH2)3 6; Ph(CH2)4 7; Ph 8; 2-pyridyl 9; 3-pyridyl 10] with various dienes using copper-oxidation b

45 -), with examples including R = Me (1a) or 3-pyridyl (1b).

46 luorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole]) of p38 MAPK.

47 meridional [Rh(IV)(pyalk)3](+) {pyalk =2-(2-pyridyl)-2-propanoate}, the first coordination complex i

48 wever, the cpCN obtained by rearrangement of pyridyl-2-((13)C-carbene) 34 carries (13)C label on all

49 three-component reaction leading to 1-alpha-(pyridyl-2-[1,2,4]triazolyl)-2-alkyl-ethanones has been d

50 of iron complexes supported by the TPA (tris(pyridyl-2-methyl)amine) ligand family with H2O2/AcOH or

51 r, emission of a framework composed of bis(5-pyridyl-2-methyl-3-thienyl)cyclopentene (BPMTC) and tetr

52 t obtained from Cp*IrL(OH) precursors (L = 2-pyridyl-2-propanoate) has been difficult to characterize

53 at units (CPDT = cyclopentadithiophene, PT = pyridyl[2,1,3]thiadiazole, IDT = indacenodithiophene) an

54 -1,3,5-triazine (TPyT) or 5,10,15,20-Tetra(4-pyridyl)-21H,23H-porphine (TPyP).

55 (trpy)](mu-bpp)}(4+) (3(4+)) (bpp(-) = bis(2-pyridyl)-3,5-pyrazolate; trpy = 2,2';6':2''-terpyridine)

56 ure-based drug design approaches, leading to pyridyl 4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolones.

57 be the straightforward synthesis of a stable pyridyl(4-methoxyphenyl)iodonium salt and its [(18)F] ra

58 e simultaneous quantifications of O(6)-[4-(3-pyridyl)-4-oxobut-1-yl]-2'-deoxyguanosine (O(6)-POBdG) a

59 (O(6)-POBdG) as well as O(2)- and O(4)-[4-(3-pyridyl)-4-oxobut-1-yl]-thymidine (O(2)-POBdT and O(4)-P

60 dihydroxy-tet rahydrofuran-2-yl]-N-[2-[[1-(2-pyridyl)-4-piperidyl]carbamoylamino]ethyl]purine-2 -carb

61 da compound 101 (Cmpd101; 3-[[[4-methyl-5-(4-pyridyl)-4H-1,2,4-triazole-3-yl] methyl] amino]-N-[2-(tr

62 Ph(CH2)2 5; Ph(CH2)3 6; Ph(CH2)4 7; Ph 8; 2-pyridyl 9; 3-pyridyl 10] with various dienes using coppe

63 d functionalized 2-pyridinyl acetates (alpha-pyridyl acetates) or teraryl motifs by a simple Lewis ba

64 The pyridyl-acyl E-hydrazone acts as a hydrogen bonding temp

65 In molecular shuttles containing pyridyl-acyl hydrazone and succinic amide ester binding

66 We report on rotaxanes featuring a pyridyl-acyl hydrazone moiety on the axle as a photo/the

67 Incorporation of 3- and 4-pyridyl-alanine (3-Pal and 4-Pal) enhanced aqueous solub

68 for the cycloaddition reaction between N-(3-pyridyl)aldimines and acetylenes where 1,5-naphthyridine

69 The mechanism of reaction of N-(3-pyridyl)aldimines with olefins can be explained by an as

70 tructs (L being a tridentate or tetradentate pyridyl/alkylamino ligand), and spectroscopic and kineti

71 The preparation of a new class of beta-pyridyl alpha-amino acid is described using a highly reg

72 ctene polymerization as catalyzed by hafnium-pyridyl amido precursors enables quantification of the a

73 -isoquinolyl)naphthalene N-oxide (2) and its pyridyl analogue 3 combine fast substrate binding with d

74 s were of the type X-Y-X, where X represents pyridyl anchors with para (p), meta (m) or ortho (o) con

75 In contrast, 2-pyridyl and 5-thiazolyl boronic acids undergo rapid prot

76 The resulting 3-pyridyl and m-hydroxyphenyl ethers have high alpha4beta2

77 ls, and how it compares with other classical pyridyl and polypyridyl based ligands, and then present

78 ds, which arise from competing influences of pyridyl and pyrazolyl ligand substituents on Fe-L sigma

79 (pyridines and quinolones) provides azaaryl (pyridyl and quinolyl) aurones and flavones under warming

80 re also attained by meta hydroxylating the 3-pyridyl and the phenyl ethers of (S)-N-methylprolinol an

81 benzo[e]indoles carrying aryl, 2-thienyl, 2-pyridyl, and alkynyl groups, in excellent yields using c

82 ort, free radical precursor, disulfide bond, pyridyl, and hydrazine moieties.

83 in this paper we describe a small library of pyridyl- and imidazolylmethylchromones as potential inhi

84 We have generated two persistent pyridyl-appended radical cations: 10-(pyrid-2-yl)-10H-ph

85 s of tungsten hydride complexes with pendant pyridyl arms ([(PyCH(2)Cp)WH(CO)(3)], PyCH(2)Cp = pyridy

86 bene, dipyridylamine, pyridyl-benzimidazole, pyridyl-azolate, and other aromatic ligands provides a c

87 The design of pyridyl-based fluorescent sensors for selective sensing

88 of these classes of compounds we termed the pyridyl benzamides.

89 When the exotridentate tris-pyridyl benzene ligand and ZnCl(2) with appropriate temp

90 2 and 1,4-bis-(4-(3,5-dicyano-2,6-dipyridyl)pyridyl)benzene (3); the latter formed in situ from the

91 ,10-phenanthroline, carbene, dipyridylamine, pyridyl-benzimidazole, pyridyl-azolate, and other aromat

92 4-(2-Pyridyl)benzo[e]indoles, upon treatment with BF(3).Et(2)

93 situations where pore chemistry is similar (pyridyl benzoate-type linkers) or identical (in the case

94 An iron(II) pyridyl-benzohydrazonate-based complex decorated with lo

95 yl group, we synthesized 3-isopropyl-7-[4-(2-pyridyl)benzyl]amino-1(2) H-pyrazolo[4,3- d]pyrimidines

96 llics are capricious coupling partners and 2-pyridyl boron reagents in particular are notorious for t

97 very slow protodeboronation, as do 3- and 4-pyridyl boronic acids (t0.5 > 1 week, pH 12, 70 degrees

98 forms a dimethylamidoiron(II) complex and a pyridyl-bridged tetrairon(II) square.

99 se adducts, including bulky O(6)-[4-oxo-4-(3-pyridyl)but-1-yl]deoxyguanosine (O(6)-POB-dG) lesions.

100 ion strategy to convert the simple 1,4-bis(3-pyridyl)butadiynes 3a,b into the fjord-edge nitrogen-dop

101 We synthesised a pyridyl-capped Anderson-Evans polyoxometalate and used i

102 on by ruthenium 2,2':6',2"-terpyridine (tpy) pyridyl-carbene catalysts reveals the importance of ster

103 Finally, pairing the strongly donating pyridyl-carbene ligand with the redox-active tpy ligand

104 d efficient NH insertion reaction of rhodium pyridyl carbenes derived from pyridotriazoles was develo

105 uorescence quenching effect was observed for pyridyl carrying push-pull porphyrin 4c in the presence

106 rongly coordinated with the nitrogens of the pyridyl coated electrodes, with a binding energy that is

107 oligophenyleneethynylene (OPE)-based Pd(II) pyridyl complex has been synthesized, and its self-assem

108 ), that the CHEF effect can be achieved with pyridyl-containing fluorophores that coordinate directly

109 vity is phenyl-linked rather than having the pyridyl core as in the peripheral cavities.

110 sponding diols 7 and 10 to the corresponding pyridyl cryptands 3 and 4 by reaction with pyridine-2,6-

111 yl)imide (PyTFSI)-templated syntheses of 2,6-pyridyl cryptands of cis(4,4')-dibenzo-30-crown-10 (3a),

112 (2-methoxyphenyl)-1-piperazinyl)ethyl))-N-(2-pyridyl)-cyclohexanecarbo xamide ([11C]WAY-100635), a se

113 lene (TCNE) at 20-90 degrees C to yield 3-(2-pyridyl)cyclopropanetetracarbonitrile 11 and 3-(tricyano

114 u treatment of the resultant quaternary N-(2-pyridyl)-DABCO salts with nucleophiles, resulting in rin

115 PEt3)2(OSO2CF3)2, with two organic donors, a pyridyl-decorated tetraphenylethylene and one of two ben

116 A series of air-stable, tunable, P-chiral pyridyl-dihydrobenzooxaphosphole ligands were designed a

117 stigate this difference for four different 2-pyridyl diketopyrrolopyrrole (DPP) polymer-fullerene sol

118 -benzo[d]imidazol-2-ylidene; py2-BMe2 = di(2-pyridyl)dimethylborate).

119 -deficient 2-pyrone substrate containing a 2-pyridyl directing group, which undergoes regioselective

120 yl) methacrylamide corona block with pendent pyridyl disulfide groups for reversible conjugation of t

121 e chain-end functionalities included alkyne, pyridyl disulfide, dopamine, beta-thiolactone, and bioti

122 with an iron complex of EDTA-2-aminoethyl 2-pyridyl disulfide.

123 roup that is appended to the 6-position of a pyridyl donor of a tripodal tetradentate ligand.

124 n situ formed carboxylic acid fluorides or 2-pyridyl esters under reducing conditions (Mn metal).

125 (bpa)] and [Cu2(glu)2(bpp)] (bpa = 1,2-bis(4-pyridyl)ethane; bpp = 1,3-bis(4-pyridyl)propane), underg

126 inked by one of three rigid ligands: 4-(2-(4-pyridyl)ethenyl)benzoate (1), 4-(pyridin-4-yl)benzoate (

127 chemical [2+2] cycloaddition of 1,4-bis[2-(4-pyridyl)ethenyl]-benzene within a porous coordination po

128 -inactive spacers consisting of 1,4-bis[2-(4-pyridyl)ethenyl]benzene (BPEB) and PdCl2 of variable thi

129 both the 3-hydroxyphenyl and the 5-hydroxy-3-pyridyl ether of N-methylprolinol are alpha4beta2 full a

130 A 3-pyridyl ether scaffold bearing a cyclopropane-containing

131 l substitution on the PP scaffold included 2-pyridyl ethers directed into the hydrophobic pocket and

132 o aryl ethers (anisoles, diaryl ethers, aryl pyridyl ethers, aryl silyl ethers), to phenolate salts,

133 ging phenolate ligand donor and two bis(2-{2-pyridyl}ethyl)amine arms), was generated from chemical o

134 below 3% for aqueous solutions of 1,2-bis(4-pyridyl)ethylene (BPE), the lowest reported to date.

135 njugate addition reactions of trans-1,2-di(2-pyridyl)ethylene have been studied.

136 ymene)4(bpe)2(donq)2][DOS]4 (bpe = 1,2-bis(4-pyridyl)ethylene, donq = 5,8-dioxydo-1,4-naphtoquinonato

137 ype MOF structure that contains 4,7-bis(2-(4-pyridyl)-ethynyl) isoindoline N-oxide and 1,4-bis(2-(4-p

138 thynyl) isoindoline N-oxide and 1,4-bis(2-(4-pyridyl)-ethynyl)-benzene pillars that connect 2D sheets

139 The unexpectedly challenging synthesis of 4-pyridyl-extended dithieno[3,2-b:2',3'-d]phospholes via S

140 their very high brightness, even in water, 4-pyridyl-extended dithienophospholes are highly promising

141 The 4-pyridyl-extended dithienophospholes display quantitative

142 The basic pyridyl functional group provides a site for the formati

143 ns are used in a second step to assemble the pyridyl-functionalized alkene into a geometry in the sol

144 via a 1D coordination polymer to generate a pyridyl-functionalized cyclobutane stereoselectively and

145 Removal of the pyridyl group affords the aldehyde-functionalized cyclob

146 roup of the dibemethin was replaced with a 2-pyridyl group and in which the 4-amino-7-chloroquinoline

147 on (not ortho or meta) of the A-ring and a m-pyridyl group as B-ring, significantly improve activity.

148 As the directing 2-pyridyl group can easily be removed at any suitable stag

149 erty analysis shows that replacing the rotor pyridyl group of our typical hydrazone switch with a phe

150 de evidence that linking hpp groups with the pyridyl group stabilizes the protonation center, thereby

151 ordination of platinum or methylation on the pyridyl group, leading to intersystem crossing to a trip

152 ryl sulfone as a replacement for the 3-cyano pyridyl group.

153 d across the molecule from the phenol to the pyridyl group.

154 ed with quaternarization of the peripheral 4-pyridyl groups (PhiF increases from 0.22 to 0.96) while

155 the relative affinity of ligands containing pyridyl groups for divalent and trivalent metal ions in

156 r optical activity and the important role of pyridyl groups in the self-assembly of these chiral macr

157 mainly attributed to the protonation of the pyridyl groups of 4c.

158 encouraging improvements in solubility when pyridyl groups were incorporated.

159 tom insertion into the CH bond of one of the pyridyl groups, forming the corresponding phenoxo-phosph

160 lexes, is a result of charge transfer to the pyridyl groups, in contrast to the free luminophore, whi

161 lexes and metalloligands with four divergent pyridyl groups.

162 ding those with halides, ethers, amines, and pyridyl groups.

163 threads that are terminated at one end with pyridyl groups.

164 s with one tetrapodal anchor and a phenyl or pyridyl head group.

165 minantly a pipi* state localized at the 1-(2-pyridyl)-imidazo[1,5-alpha]pyridine (= impy) ligand core

166 aracters and dynamics of [ReCl(CO)3(3-R-1-(2-pyridyl)-imidazo[1,5-alpha]pyridine)] complexes (abbrevi

167 adiene) and a phenanthroline ligand or a new pyridyl-imidazoline ligand that further increases the re

168 aving N-heterocyclic substituents, including pyridyl, imidazolyl, pyrimdyl, and other groups.

169 ge to produce an electrophilic C-3 site in N-pyridyl indole.

170 here there is a clear hierarchy for zinc(II)-pyridyl interaction followed by hydrogen-bonding between

171 se of Turbo Grignard generated the metallo-2-pyridyl intermediate more reliably than alkyllithium rea

172 rough three different interactions: a strong pyridyl-iron one, and two weaker carboxamido-iron ones t

173 oped into a series of potent and selective 3-pyridyl isoindolin-1-ones CYP11B2 inhibitors.

174 dional isomers of [Ir(pyalk)3] (pyalk = 2-(2-pyridyl)isopropanoate), as model complexes for a powerfu

175 strates at room temperature gave 3-hydroxy-4-pyridyl-isoquinoline derivatives in good yields.

176 Di-2-pyridyl ketone (dpk)-supported amidoarylpallada(II)cycle

177 toolbox for the controlled assembly of di(2-pyridyl) ketone (dpk) with M(OAc)(2) (M = Co, Ni) precur

178 The use of di(2-pyridyl)ketone in subcomponent self-assembly is introduc

179 a hypervalent F-iodane mediated umpolung of pyridyl ketones triggered by Lewis base/Lewis acid nonco

180 Migration of the pyridyl ligand (or its pyridylidene tautomer) to the alp

181 st assembly step, BCPs functionalized with a pyridyl ligand on the chain end form star-shaped polymer

182 the electron-donating ability of the distal pyridyl ligand set at the Co sites demonstrating strong

183 hesized by the self-assembly of a tetratopic pyridyl ligand with a 180 degrees diplatinum(II) motif a

184 The combination of pyridyl ligands and square-planar Pd(ii) or Pt(ii) catio

185 Here the binding of pyridyl ligands to zinc porphyrins with thioester-linked

186 s(heteroleptic) Ir(III) compounds containing pyridyl ligands with weakly coordinating nido-carboranyl

187 porphyrins bearing either 4-aminophenyl or 4-pyridyl meso substituents were performed using methanesu

188 abling the first access to key precursors of pyridyl-mesoionic carbene ligands.

189 (phen = 1,10-phenanthroline; pyr(3) = tris-2-pyridyl-methane).

190 (5) and (dpms)Pd(II)Me(OH2) (8) (dpms = di(2-pyridyl)methanesulfonate) in water in the pH range of 6-

191 ) and (dpms)Pt(II)Me(OH)(-) (2) [dpms = di(2-pyridyl)methanesulfonate] in water in the pH range of 4-

192 u-OH)2}(OTf)2 (L = Me2TMPA = bis((6-methyl-2-pyridyl)methyl)(2-pyridylmethyl)amine) in which water ox

193 H4)CH3)DPFN]NTf2 (DPFN = 2,7-bis(fluoro-di(2-pyridyl)methyl)-1,8-naphthyridine; NTf2(-) = N(SO2CF3)2(

194 )2C6H3, and C6F5; DPFN = 2,7-bis(fluoro-di(2-pyridyl)methyl)-1,8-naphthyridine; X = BAr4(-) and NTf2(

195 sence of the capping ligand tris((6-methyl-2-pyridyl)methyl)amine (Me3TPyA) affords the dinuclear com

196 rescein and rhodamine dyes through a Tris[(2-pyridyl)methyl]amine bridge.

197 We describe a new photocage, {bis[(2-pyridyl)methyl]amino}(9-oxo-2-xanthenyl)acetic acid (XDP

198 rboxylation, the analogous photocage {bis[(2-pyridyl)methyl]amino}(m-nitrophenyl)acetic acid (DPAdeCa

199 O)](2+) (N4Py: N,N-bis(2-pyridylmethyl)bis(2-pyridyl)methylamine), is the least basic oxidant.

200 tate ligand N,N-bis(2-pyridylmethyl)-N-bis(2-pyridyl)methylamine, has been proposed to attack C-H bon

201 ren(py)(3))](2+) (where tren(py)(3) = tris(2-pyridyl-methylimino-ethyl)amine) and a series of benzoqu

202 pump inhibitors having the core structure, 2-pyridyl-methylsulfinyl-benzimidazole.

203 ian cones and horizontal cells showed that 2-pyridyl-methylsulfinyl-benzimidazoles blocked the negati

204 onal prismatic primary MBBs decorated by six pyridyl moieties (tp-PMBB-1).

205 unctionalized double-bridged tweezer bearing pyridyl moieties and the tetra-carboxylated linker.

206 de evidence that axial-coordination from the pyridyl moieties in poly-4-vinylpyridine to the cobalt p

207 ethyl derivatives in position 9, substituted pyridyl moieties in position 4 and small alkyl groups in

208 as oxidation or amine quaternization, of the pyridyl moiety carried by the alkyl fragment was suitabl

209 CDK-bound form of CR8 has a solvent-exposed pyridyl moiety that induces the formation of a complex b

210 functionalizing every primary CH2OH with a 4-pyridyl moiety.

211 hat BDPA-2Me, with Me groups adjacent to the pyridyl N, has the longest B-N distance and shows overal

212 tly organized PT orientations, such that the pyridyl N-atoms point toward the CPDT fragment.

213 binding salicylaldehyde unit and an adjacent pyridyl N-oxide fluorophore undergoes rapid condensation

214 into spin adducts of the spin trap alpha-(4-pyridyl N-oxide)-N-tert-butylnitrone (POBN).

215 The N-(2-pyridyl)-N'-ethylpiperazines are important structural mo

216 -[4-(2-methoxyphenyl)piperazinyl]ethyl}-N-(2-pyridyl)-N-(trans-4-(18)F-fluoro methylcyclohexane)carbo

217 [Ru(tpy)(Mebim-py)(OH(2))](2+) (Mebim-py = 2-pyridyl-N-methylbenzimidazole), catalyze water oxidation

218 inhibitors were designed leading to the 2-(3-pyridyl)naphthalenes 10 and 11 with strong inhibition of

219 qdpq; bpy = 2,2'-bipyridine; qdpq = 2,3-di(2-pyridyl)naphtho[2,3-f]quinoxaline-7,12-quinone) possesse

220 C-(2-Pyridyl)nitrile imine 38 is predicted to undergo a new r

221 The four pyridyl nitrogen atoms define a perfectly planar rectang

222 Subsequent nucleophilic attack by pyridyl nitrogen results in its cyclization.

223 ue to the positive charge centralized on the pyridyl nitrogen, N-H(+).

224 ovide a toolset for the predictive design of pyridyl nitroxides.

225 h oxalamide host molecules containing either pyridyl or nitrile side groups, in which halogen bonds a

226 This approach provides rapid access to pyridyl (or pyridone)-substituted 1,3,5-triazines with h

227 itives (e.g., Cu, Zn salts) can attenuate (2-pyridyl) or accelerate (5-thiazolyl and 5-pyrazolyl) fra

228 A series of novel pyridyl- or isoquinolinyl-substituted indolines and indo

229 beta-stereocenters was developed using a new pyridyl-oxazoline ligand.

230 the two 5'-methylated analogs of the potent pyridyl oxymethylene-bridged nicotine analog A84543 were

231 The resulting 2,6-bis(imino)pyridyl-Pd(II) motif contains a tridentate ligand, leavi

232 hips demonstrated the importance of the di-2-pyridyl pharmacophore in their activity.

233 , forming a stable Rh(II) radical Cp*Rh(2-(2-pyridyl)phenyl)* (14a) that can activate H2 at room temp

234 e high energy of the Rh(I) anion [Cp*Rh(2-(2-pyridyl)phenyl)](-).

235 d for the Rh(III) hydride complex Cp*Rh(2-(2-pyridyl)phenyl)H (1a).

236 spontaneous hydrolysis of the anion of di-2-pyridyl phosphate (DPP) is thousands of times faster (ca

237 ace-bound phosphonate derivatives with L = 4-pyridyl phosphonic acid or diethyl 3-(pyridin-4-yloxy)de

238 coupling reaction has been developed between pyridyl phosphonium salts and cyanopyridines using B(2)

239 hlorpyrifos (O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate) (CP) in tomato by HPLC-DAD.

240 Mn(III) Tetrakis (1-methyl-4-pyridyl) porphyrin (MnTMPyP), an antioxidant, reduced su

241 ionic porphyrin (5,10,15,20-tetra(N-methyl-4-pyridyl) porphyrin (TMPyP4)), which can bind some G-quad

242 With water-soluble iron tetrakis(N-methyl-4-pyridyl)porphyrin as an example, procedures are describe

243 eous catalysis with iron tetrakis(N-methyl-4-pyridyl)porphyrin has been overlooked in previous studie

244 -) scavenger, iron-(III)-tetrakis(N-methyl-4'pyridyl)porphyrin-pentachloride, or uric acid, whereas e

245 hniques on monomeric cobalt(II) tetra(meso-4-pyridyl)porphyrinate (CoTPyP) and its cofacial analogue

246 A CF3-thiazole substituent at the 4-pyridyl position improved inhibitory potency due to a fa

247 nd acid isosteres were incorporated at the 5-pyridyl position of this fragment, bridging to a key asp

248 d the neutral N-donor spacer ligand 1,3-di(4-pyridyl)propane (dpp) lead in a single reaction vial to

249 = 1,2-bis(4-pyridyl)ethane; bpp = 1,3-bis(4-pyridyl)propane), undergo spontaneous phase changes upon

250 te in an ethanol-water system with 2,3-bis(2-pyridyl)pyrazine yielded basic bismuth nitrate Reuleaux

251 ) (bpy = 2,2'-bipyridine and dpp = 2,3-bis(2-pyridyl)pyrazine) catalyze the photochemical reduction o

252 l2 ](5+) (bpy=2,2'-bipyridine, dpp=2,3-bis(2-pyridyl)pyrazine).

253 halides on aniline derivatives as well as on pyridyl-, pyrimidyl-, and pyrazolyl-substituted arenes.

254 isiae to copper is overcome by 2-(6-benzyl-2-pyridyl)quinazoline (BPQ), providing a chemical-biology

255 coupling process between a boryl phosphonium pyridyl radical and a boryl-stabilized cyanopyridine rad

256 through a Minisci-type coupling involving a pyridyl radical.

257 oline can be synthesized through reaction of pyridyl radicals with 1,3-butadiene or sequentially with

258 chors that form only S-Au or N-Au bonds, the pyridyl ring also forms a highly-conductive cofacial lin

259 with Me groups in different positions of the pyridyl ring have been prepared via directed electrophil

260 Substitution of the pyridyl ring in the 3-, 4-, and 5-positions was used to

261 cisely installed on the synthesized aryl and pyridyl ring is a highly versatile moiety, which is effo

262 ting electrophiles at the C5 position of the pyridyl ring of 2 (OL-135) and related compounds were pr

263 all modifications in the substitution of the pyridyl ring of BN-fused dipyridylanthracenes change the

264 ds through the stronger interaction with the pyridyl ring, which enables reversible unfolding and ref

265 nding between uranium cations and the eta(5)-pyridyl ring.

266 respect to the position of the N atom on the pyridyl ring.

267 ning functional groups such as thiophenes or pyridyl rings that can challenge transition-metal cataly

268 pair, spiro[2.3]hex-1-ene (Sph) and 3,6-di(2-pyridyl)-s-tetrazine (DpTz), for the strain-promoted inv

269 dine-6,6'-dicarboxylate) with phosphonate or pyridyl sites for water oxidation, gives surfaces with a

270 The regioselectivity is guided by the pyridyl substituent attached to the nitrogen center of t

271 The strict regioselectivity is guided by the pyridyl substituent attached to the nitrogen of the pyri

272 aced electrophiles at the C5 position of the pyridyl substituent of 2 (OL-135) were prepared and exam

273 cytochrome P450 enzymes, probably due to a 4-pyridyl substituent.

274 f ditopic perylenediimide 16, containing two pyridyl substituents at its imido positions, enabled sel

275 Pyridyl substituted arylsulfonyltetrahydroquinolines wer

276 s work in our laboratory, NAP, a 6beta- N-4'-pyridyl substituted naltrexamine derivative, was identif

277 lly, iron(II) is cis-coordinated to two N-(2-pyridyl)-substituted N-heterocyclic carbene (PyNHC) liga

278 Pyridyl-substituted 1,3,5-triazines were synthesized in

279 The new pyridyl-substituted 3H-naphtho[2,1-b]pyrans display good

280 An array of six pyridyl-substituted fused bicyclic piperidines was prepa

281 kappa(2)-N-eta(2)-BC Pt complexes of a boron-pyridyl-substituted monobenzofused-1,4-azaborine.

282 n be increased with the incorporation of a 2-pyridyl substitution on the boratriazaroles, and the str

283 of terminal and internal alkynes bearing a 2-pyridyl sulfonyl group (SO2Py) at the propargylic positi

284 nding on the presence or absence of the N-(2-pyridyl)sulfonyl group.

285 lation reaction taking advantage of the N-(2-pyridyl)sulfonyl group.

286 e H-transfer from the tetrazole ring in 5-(2-pyridyl)tetrazole to the pyridine ring with a subsequent

287 ntaining ligand L, composed of two bidentate pyridyl-thiazole moieties linked by a 1,3-diaminophenyle

288 terestingly, the substituted groups (phenyl, pyridyl, thienyl) in the 1,4-positions did affect their

289 esters, N-hydroxyphthalimide esters and S-2-pyridyl thioesters, to form aryl alkyl and dialkyl keton

290 e molecules with different anchoring groups (pyridyl, thiol, amine, nitrile and dihydrobenzothiophene

291 mine bond formation is employed to install a pyridyl to the alkene trans-cinnamaldehyde while Ag(I) i

292 was prepared by C-(11)C-methylation of the 3-pyridyl trifluoroborate precursor with (11)C-methyl iodi

293 II) metalloporphyrin backbone bearing both a pyridyl unit and a terpyridyl unit acting as coordinatin

294 parallel arene moieties of the wheel and the pyridyl unit of axle are operative in addition to metal

295 ended tetrathiafulvalene ligand bearing four pyridyl units and cis-M(dppf)(OTf)2 (M = Pd or Pt; dppf

296 romic 3H-naphtho[2,1-b]pyrans decorated with pyridyl units are described.

297 ) tetrahedron 1 bearing twelve uncoordinated pyridyl units around its metal-ion vertices.

298 430 (1-(2,6-dibromo-4-isopropyl-phenyl)-3-(3-pyridyl)urea, molecular weight = 413), with antagonist p

299 omplex is stabilized by electron-withdrawing pyridyl ("X") substituents, but also by electron-donatin

300 r to stitch easily and appropriately crafted pyridyl ynones through a transition-metal-free, tandem M