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1 ce of emotion as a test case to explore this question.
2 of E(4)(4H) provides a means to address this question.
3 ferentiation is a fundamental yet unanswered question.
4 tes to tissue morphogenesis is still an open question.
5 However, this view has also been called into question.
6 ader relevance to cuprate physics is an open question.
7 s transcription or DNA repair remain an open question.
8 mental mouse models that try to address this question.
9 incipled theoretical analysis to answer this question.
10 ed at the gene expression level are critical questions.
11 ing approaches have led to new paradigms and questions.
12 rogress, however, has brought up several new questions.
13 to more often include spatial components and questions.
14 gist will consider when planning to ask bold questions.
15 igators with an emphasis on significant open questions.
16  on the interpretation of various biological questions.
17 nic chemistry and pose countless outstanding questions.
18 function and articulate important unanswered questions.
19  seven-point Likert scale or with open-ended questions.
20 nd lower vertebrates and ask two fundamental questions.
21  145 adults confirmed the reliability of the questions.
22 ith the current COVID-19 pandemic need to be questioned.
23 y, the processes within these subsystems are questioned.
24 peciation and mitochondrial disease has been questioned.
25 ortion of participants responding "never" to question 1 of the Intraocular Lens Satisfaction question
26                            We focused on two questions: 1) What is the native size and what are the d
27                           Here, we asked two questions: (1) Is it possible to use nucleic acid quanti
28                               We address two questions: (1) what sleep-related/fatigue-management int
29 literature citations associated with 10 PICO questions, 20 relevant studies were identified.
30                       This result calls into question a foundational assumption of extant models of v
31                 These observations raise the question about whether enhancement of the circadian cloc
32 he desired health gains, raising fundamental questions about current approaches.
33                         These findings raise questions about documentation accuracy and utility and m
34       These structures are allowing detailed questions about functional mechanisms of the structures,
35 d residency <= 10 years ago and responded to questions about gender, fellowship training, state of pr
36 f a limited number of European species raise questions about how macro- and microevolutionary process
37 ubsequent observations of Fomalhaut b raised questions about its status: Unlike other exoplanets, it
38 ed via a web-based platform and responded to questions about loss of smell and taste and other COVID-
39 ive tests and multiple choice responses to 6 questions about mental health between groups using the t
40 e survey instrument in a different district, questions about socio-demographic status were delivered
41 ening for COVID-19 typically includes survey questions about symptoms and travel history, as well as
42 he field to struggle with several conceptual questions about the developmental origin of the cell and
43 s versus what isn't remembered, leaving open questions about the effect of dopamine replacement on th
44 ces in A. cahirinus sleep architecture raise questions about the evolutionary drivers of sleep behavi
45                The Flint water crisis raised questions about the factors resulting in unacceptable so
46         The age estimate also raises further questions about the mode of evolution of H. sapiens in A
47  statistical methods to comparatively framed questions about the molecular dynamics (MD) of proteins
48 e Wind Scale) hurricane landfalls, prompting questions about the natural range in variability of hurr
49 are are normal, unwarranted variations raise questions about the quality, appropriateness, and cost-e
50 is Matters Arising article raise fundamental questions about the recently proposed role for STK19 in
51                         Meanwhile, there are questions about the reliability of STP dosimetry, with l
52 l cations can substitute for Mg(2+), raising questions about the role different metals may play in th
53 which may be helpful for answering important questions about the role of metabolism in T cells.
54 topological organization is unknown, raising questions about the subcellular localization of the fina
55 pets, such as cats, ferrets and dogs, raises questions about the susceptibility of animals under natu
56 o susceptibility regularly appear, prompting questions about which pressures compete with antibiotics
57 ngly agreed with IDD when posed as a general question and in relation to the case scenario.
58 analysis expounds on what is known about the question and what was identified as priorities for ongoi
59 ts in this area to highlight future research questions and direct future clinical trials.
60                      We identify outstanding questions and methodological challenges that need to be
61 tained by in situ TEM to address fundamental questions and practical issues regarding phase transform
62 nal approaches for exploring cell biological questions and provide a framework for decision making by
63        I conclude by presenting key research questions and topics in this domain that should be at th
64  has expanded far beyond this initial set of questions and will also greatly inform our understanding
65 itable bowel syndrome (IBS) and constipation questions, and the SF-8 quality of life questionnaire.
66 method appropriate to answering real-time IR questions, and working with local researchers or researc
67         Our results suggest that pedagogical questions are a relatively simple educational manipulati
68 merging treatments, and outstanding research questions are addressed.
69                           Several unresolved questions are discussed in the context of astrobiology,
70          Unanswered scientific/technological questions are identified, emerging research opportunitie
71 timulator vericiguat in HFrEF, the main open questions are the efficacy of the sacubitril/valsartan-v
72                       Two important clinical questions are whether there is a subtype of schizophreni
73                              Thus, a natural question arises: how are asynchronous population dynamic
74 ity score stratification using this clinical question as a case study to guide the reader through (1)
75                              This raises the question as to the translatome remodelers that titrate p
76                    Dispensary employees were questioned as to whether marijuana was recommended and w
77 lle was discovered 120 years ago, such basic questions as whether vesicular transport through the Gol
78 l, extremely G protein-biased agonists is in question, as is the underlying assumption that beta-arre
79              Here we highlight many of these questions, as well as provide a proposed model for syste
80 ve been used for various pathogens and study questions, as well as the most common difficulties assoc
81                     This raises an important question: as past research shows that offspring would be
82 ard a paradigm that formulates RNA-targeting questions at the level of RNA structural subclasses.
83                   Here, we address this open question by combining topographically patterned substrat
84                    We have investigated this question by combining whole-brain volumetric calcium ima
85 e studies that are beginning to address this question by investigating fundamental properties of lncR
86                        Here, we address this question by investigating some biophysical properties of
87                            We addressed this question by measuring the free energy change for a numbe
88                             We examined this question by separately manipulating both the value-drive
89                         Here we address that question by trapping an early state of pore formation fo
90                           We addressed these questions by carrying out high channel count recordings
91                             We address these questions by reviewing published literature on aquatic i
92          In this paper, we discuss how these questions can be approached and examine the merits and d
93                                  Our results question certain existing studies using GW9662 and make
94                                  Outstanding questions concern the precise nature of the intermediate
95  in ZIKV cases since the 2015-2016 epidemic, questions concerning the prevalence and longevity of pro
96 reas during intense glacial stages and raise questions concerning understudied migration pathways, su
97  health threat, highlighting the outstanding questions critical to our understanding of this potentia
98  assessed by telephone from responses to the question, "Did you happen to miss any dose of your medic
99 odstream infections, we sought to answer the question "Does transitioning patients with gram-negative
100                              This raises the question: Does interdisciplinary research collaboration
101  Unlike previous studies that addressed this question either by focusing on impaired sensory processi
102                              To address this question empirically, we bridged art theory and cognitiv
103  test about basic semiology and answered two questions evaluating their degree of confidence in inter
104                        The results call into question fears about the vanishing potential for inciden
105                                      New key questions focused on the yield of alternative HBV screen
106                 We now directly address this question for NMDA receptor-dependent long-term depressio
107                              To address this question for transcription factors of the nuclear factor
108 We conclude with a discussion of outstanding questions for future research.
109 onmental heterogeneity and poses challenging questions for understanding the speciation process for o
110 tor models and highlight 3 types of research questions for which bifactor models are well suited to a
111 review is to determine whether the following questions have been sufficiently answered in the open li
112 mic surveys reveal great sequence diversity, questioning how SD functions.
113  of vast allelic polymorphism raises several questions-How do different signaling variants interact w
114                   Previous reports raise the question if motor function is modulated by substrate DNA
115 he RNA world scenarios, it is an interesting question, if charge transfer can be coupled with RNA fun
116                            We addressed this question in a seasonally breeding songbird and found tha
117                                      An open question in aggressive cancers such as melanoma is how m
118 n a fluctuating environment is a fundamental question in biology.
119                      An important unanswered question in chromatin biology is the extent to which lon
120                                 An important question in early neural development is the origin of st
121  is an important, but not yet fully resolved question in ecology.
122         The origin of nucleotides is a major question in origins-of-life research.
123 mic response, highlighting a new fundamental question in plant biology: are plants capable of integra
124                          Here, we study this question in the context of collaborative problem-solving
125 am-negative or diderm) is a fundamental open question in the evolution of Bacteria.
126 red in single cells, to answer an unresolved question in the field-whether receptor endocytosis is re
127 activation of latent virus is a longstanding question in the field.
128 als and female preferences remains a central question in the study of animal communication.
129 iverse protein-protein interactions is a key question in understanding the HSV-1 life cycle and patho
130                Here, we have addressed these questions in a series of genome-wide experiments coupled
131                                      Focused questions in adult outpatients with moderate to severe U
132  is key to answering diverse and fundamental questions in biology.
133 um simulation to find answers to outstanding questions in condensed-matter physics.
134        We review progress and highlight open questions in neuroaesthetics.
135 rgently needed to address important clinical questions in patients with kidney disease.
136 ic structure is essential for answering many questions in population genetics.
137 eeking a MS-based tool to address structural questions in protein science.
138 recent progress in AI toward answering these questions in the domain of visuospatial reasoning, looki
139 n of C-C bonds is one of the key fundamental questions in the field of CO(2) electroreduction.
140 ansplantation (AST) launched the Outstanding Questions in Transplantation Research forum to stimulate
141                           Important clinical questions include: Why is there a variable occurrence of
142 T by highlighting studies of a wide range of questions, including the mechanism of activation and tra
143                                         This question is best addressed in a genetic mapping populati
144                           The answer to this question is critical especially for some pathological st
145                           A major unresolved question is how bacteria living in complex communities r
146                                    A central question is how direct photochemical electron delivery f
147                                          The question is how to achieve this.
148                                          The question is particularly relevant for people with immune
149                                   A pressing question is to understand how large-scale cross-linking
150                                   An ongoing question is whether DWF is a consequence of chronic allo
151                             A key unanswered question is whether infection with SARS-CoV-2 results in
152                              One outstanding question is whether the myosin heavy chain (MHC) isoform
153 e shown similar mortality, but the essential question is whether the sensitivity and specificity of p
154                           One key unanswered question is whether we can select for a plant microbiome
155 Although this hypothesis has been repeatedly questioned, it has never been tested on a large sample s
156          As different methods suit different questions, it may not be possible to produce a "one-size
157 h) century and led some researchers to later question its value as a model organism.
158 lecular biology are still nascent, with many questions largely unexplored, thus hindering our ability
159                                   Answers to questions like 'Is a variant perturbing a site involved
160 and after the workshop, students did a seven-question multiple-choice test about basic semiology and
161 ibit vastly greater complexity, which raises questions not addressed by this bacterial paradigm.
162 g; these findings resulted in the open-ended question of "What does this mean for imagers?" (C) RSNA,
163                We addressed this fundamental question of causality using longitudinal anatomical magn
164                              This raises the question of defining the specific host and bacterial fac
165 imit of 39 nanometres(4-7), which raises the question of how larger cytoplasmic molecules are cleared
166 performance of behavioral tasks, raising the question of how recorded activity relates to theoretical
167 nt for tumor development, thus prompting the question of how single mutant cells give rise to neoplas
168 s heterogeneous methylomes, thus raising the question of how the DNA methylome remains stable despite
169 ptide fragments from ssDNA ends, raising the question of how the ~90 kDa TOP1 protein is processed up
170 ht assembly on the trains [3], provoking the question of how these motors coordinate their action to
171 et of Esx, PE, and PPE proteins, raising the question of how these substrates are recognized in a sys
172                    This naturally raises the question of how to maximize health and longevity in an a
173                                          The question of how we selectively create temporal stability
174  in this direction by addressing the crucial question of identifying the processes which act as the m
175  can make patterns related to the scientific question of interest difficult to observe.
176                 In this work, we revisit the question of learning in volatile environments, in which
177                            Particularly, the question of the impact of extreme total ionizing dose on
178                 This manuscript explores the question of the seasonality of severe acute respiratory
179 during interglacial periods, this raises the question of the significance of bird migration during pa
180 es of subtype transdifferentiation raise the question of to what extent the tumor characteristics are
181 iomarkers in the estimation of prognosis and question of treatment.
182                      These results raise the question of whether biodiversity-disease relationships a
183                              This raises the question of whether cooperation can emerge and persist d
184                     These findings raise the question of whether social communication and irritabilit
185  rapid eye movement sleep (REM), raising the question of why and how specialized sleep evolved.
186 his emotion into account, we can address the question of why humans seek to learn, teach, and innovat
187            Our findings answer a decades-old question on the function of terminal web myosin and hold
188 i imaging approaches can address fundamental questions on chromatin dynamics in a range of model orga
189                       A subsection completed questions on consumption of fruits and vegetables, fast
190 recent insights and identify the outstanding questions on how dynamic control of the long-term stabil
191  These observations open new and interesting questions on the function and regulation of the E/I bala
192 is lack of positive results in turn prompted questions on whether inflammation is a cause or conseque
193 tion, intervention, comparison, and outcomes questions) on the management acute or acute on chronic l
194 s limited knowledge specific to the virus in question, other than its genome sequence.
195 in single live cells to address cell biology questions otherwise intractable and engineer cell functi
196            The implications of our findings, questioning previous assumptions but also reinforcing th
197 not geolocators can answer proposed research questions, provide guidance in choosing an appropriate a
198            We discuss the unique biophysical questions raised by the presence of large extracellular
199 ting from alcohol use are evident, some open questions regarding alcohol use and its consequences in
200 hitin production has been detected and raise questions regarding chitin's potential function in chond
201 JUHI, were aged 68 to 73 y, and responded to questions regarding past dental visits.
202 opulation dynamics, they leave open numerous questions regarding the biological characterization of t
203                     These observations raise questions regarding the biological role of tooth-innerva
204 ovides an overview of UKD and answers common questions regarding the ethical considerations, clinical
205                 To help address several open questions regarding the history of these movements, we g
206                         However, outstanding questions regarding the NMR application remain.
207                       Individually, only the questions regarding the self-perception of teeth/gum hea
208     These striking results raise fundamental questions regarding tumor innervation, how it is initiat
209 O(2), allowing us to address a long-standing question related to Ni-catalyzed carboxylation reactions
210                                    A central question related to virtually all social decisions is ho
211 t past resource use, and hence address major questions relating to patterns of subsistence, diet and
212         Finally, we outline further research questions relating to this complex and evolving treatmen
213       Despite numerous animal model studies, questions remain about local immune characteristics in h
214                                However, many questions remain about the role of the protein hydration
215                                     However, questions remain about whether autophagy has a protectiv
216                                    Important questions remain regarding the molecular mechanisms that
217                                        Major questions remain regarding which cellular reducing syste
218 root nodules has a high demand for iron, and questions remain regarding which transporters are involv
219 ttention over the past few decades, yet many questions remain unanswered regarding patterns in their
220 l mechanisms governing differentiation, many questions remain unanswered regarding the involvement of
221                                     However, questions remain whether small animal models accurately
222 etes is a complex area in which many further questions remain, especially regarding the well-conducte
223                                          Key questions remain, such as the Ag dependence of signal 4
224 izumab with or without corticosteroids, with questions remaining regarding the optimal management of
225                                 However, the question remains as to whether adjuvant-dependent modula
226                                          The question remains exactly how such surplus pooling occurr
227 tals have size-dependent properties, yet the question remains whether nanocrystal properties can be a
228                   In discussing all of these questions, special attention is paid to novel quantum ef
229       This is related to another fundamental question: Starting from many copies of noisy quantum clo
230         Though RRV vCD200 has been examined, questions still exist in regard to the ability of this m
231 alvage radiotherapy, and to address emerging questions such as the relative value of tissue biomarker
232                                 Yet, ongoing questions, technical challenges, and unresolved controve
233   Performance on case-based, multiple-choice question tests before and after each intervention was us
234         With current research providing more questions than answers, it is about time to investigate
235                            Here we address a question that can rarely be answered for endemic pathoge
236 uces or increases infectious disease risk, a question that directly affects policy decisions for biod
237                              One fundamental question that remains to be directly addressed is whethe
238 llow researchers to address major biological questions that are more than the sum of the parts.
239 ecology stand to grow as fields by exploring questions that arise at their intersection.
240 ficiency photocatalysts followed by six open questions that may need to be resolved by forming a glob
241                  The approach considers four questions that often present themselves to medicinal che
242 this disorder and outline a few of the major questions that remain to be answered.
243 synthesized, trafficked, and stored are also questions that require closer inspection.
244 lecular medicine to rapidly advance, answers questions that traditional interventional trials general
245 lexibility of leatherwood and also call into question the classical model of lignification, which pur
246                       Our findings call into question the conventional view that tumor-associated epi
247                               These findings question the descriptive validity of normative accounts,
248                                These results question the ecological relevance of OCLTT for Tigriopus
249                            These conclusions question the existence of refuge areas during intense gl
250                     Recent empirical results question the general validity of this explanation.
251 elp washed up on Antarctic beaches led us to question the permeability of these barriers to species d
252                        Our results call into question the predominant thinking that the capacity of f
253 s random assembly has led some ecologists to question the relevance of biodiversity experiments to re
254 lar trade-offs will be evident, calling into question the ubiquity of resistance management based on
255 ls devoid of such pathologies, bringing into question the underlying processes that may be at play du
256                          Recent studies have questioned the use of omentoplasty for the prevention of
257  results in detrimental pleiotropic defects, questioning the purpose of the miR159-GAMYB pathway.
258 onal area-a predictor of disability-is poor, questioning the unique role of axonal loss.
259                                         This questions the validity of curvature-based alignment (CBA
260 erimental and modeling studies have begun to question this long-held belief.
261          To provide novel insights into this question, this study combines electrophysiological asses
262                        Here, we examine this question through the lens of genome sequence data for fi
263 political circumstances, this is a difficult question to answer, but the novel coronavirus pandemic a
264                                          The question to ask is whether RS can be used to detect CBD
265 onnaire with 0-10 analogue scores and yes/no questions to determine reflux symptoms, side-effects and
266 of the role of imaging in answering specific questions to help predict the management needs of each i
267 ata was collected by a questionnaire with 37 questions to the Nordic oculoplastic surgeons and analyz
268 nd we propose a means of refocusing research questions towards the rich and complex components that c
269                            We addressed this question using a demographic dataset of female Asian ele
270        Here, we address some aspects of this question using a technical tour de force approach to sys
271                              We explore this question using the case of Chinese internationals in the
272             We have probed these fundamental questions using the fission yeast Schizosaccharomyces ja
273                     Evidence review informed questions using the modified Delphi model.
274                                          The question we have addressed concerns the differences and
275                              To address this question, we collected hours of functional magnetic reso
276                              To address this question, we conducted two functional MRI experiments in
277                              To address this question, we developed a polymeric-based constructed gra
278                              To address this question, we have expanded the toolbox of Forster Resona
279                              To address this question, we investigated neural and inflammatory marker
280                               To answer this question, we measured evapotranspiration and carbon diox
281                              To address this question, we modified a regulatable fluorescent secretor
282                              To address this question, we perform benchmark studies on simulated and
283                              To address this question, we recorded from LSO neurons in slices from pr
284                              To address this question, we studied a unique cohort of 1,196 children w
285                              To address this question, we study a minimal but generic model for a nem
286                              To address this question, we used a combination of viral shRNA and condi
287                              To answer these questions, we must be able to detect and quantitate cGAM
288                             To address these questions, we performed 16S sequencing on fecal DNA samp
289                             To address these questions, we report an experimental and theoretical inv
290                             To address these questions, we trained rhesus monkeys to perform a novel
291                          In this study these questions were addressed for the Clavata3/Endosperm Surr
292                              This raises the question: what are the translatome remodelers that repro
293 , AND METHODS: The paper seeks to answer two questions: What are the characteristics of the minimally
294                              This raises the question whether the penetrance is indeed 100% as genera
295 ents perform stepping movements, raising the question whether the STN is involved in the dynamic cont
296 nction of terrestrial beavers and raises the question whether the two events had a common cause.
297 quency content up to 300-400 Hz, raising the question whether vestibular pathways contribute to head
298                              To address this question while avoiding confounding effects of cardiomyo
299                             Answers to these questions will aid both the understanding of molecular-s
300                             We address these questions with two nationally diverse, online surveys fi

 
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