ライフサイエンスコーパス: rack

1 87.5% versus 50%, control versus psi(epsilon)RACK).

2 ns such as receptors for activated C kinase (RACKs).

3 e mice, but can also be operated outside the rack.

4 r hidden when active epsilonPKC binds to its RACK.

5 he binding of each isozyme to its respective RACK.

6 ills the criteria previously established for RACKs.

7 verbal message were displayed above bicycle racks.

8 s for activated C kinase collectively called RACKs.

9 items to automobile rooftops and to bicycle racks.

10 ed the recovery of larger wine volumes after racking.

11 , mitogen-activated protein kinase kinase 5, RACK 1, apolipoprotein C-III, and the gene encoding the

12 ins such as receptor for activated C kinase (RACK) 1 are involved in the targeting of signaling prote

13 ein receptor for activated protein kinase C (RACK)-1 has been linked to a variety of signaling system

14 aRbetaL and a previously identified protein, RACK-1 (receptor for activated C kinase).

15 ion (Ki = 11.5 +/- 5 microM) with respect to RACK-1 (receptor for activated C kinase-1), an adaptor p

16 ng leukocyte protein of 76 kDa), p62dok, and RACK-1 (receptor for activated protein kinase C-1).

17 The interaction between RACK-1 and IFN-alphaRbetaL, but not the human IFN recept

18 type I IFN signaling because mutation of the RACK-1 binding site in the IFN-alpha receptor 2/beta sub

19 RACK-1 binding to IFN-alphaRbetaL did not require the fi

20 ain of IFN-alphaRbetaL, the minimum site for RACK-1 binding was mapped to aa 300-346.

21 slocation by inhibiting formation of the PKC.RACK-1 complex.

22 We found that RACK-1 directly binds to DNC-2, the C. elegans p50/dynam

23 Our findings suggest a mechanism by which RACK-1 directs the dynactin-dependent redistribution of

24 In the IFN system, RACK-1 functions as an adaptor recruiting the transcript

25 RACK-1 is also required for proper chromosome separation

26 RACK-1 itself did not become tyrosine phosphorylated upo

27 RACK-1 localizes to the centrosomes, kinetochores, the m

28 Finally, we provide evidence that RACK-1 may also serve as a scaffold protein in other cyt

29 Last, RACK-1 may facilitate the sequestration of recycling end

30 In this study, we demonstrate that RACK-1 serves as a scaffold protein for a multiprotein c

31 However, RACK-1 should play a broader role in type I IFN signalin

32 In overlay assays with native RACK-1 that had been immobilized on nitrocellulose, UV-t

33 RACK-1 was shown to be constitutively associated with IF

34 is elegans Receptor of Activated C Kinase 1 (RACK-1) is required for cytokinesis, germline membrane o

35 , UV-treated control PKC alpha bound well to RACK-1, whereas UV/DECA-inactivated PKC alpha had reduce

36 phaRbetaL did not require the first 91 aa of RACK-1, which includes two WD domains, WD1 and WD2.

37 s increases the interaction between NR2B and RACK-1, which is also dependent on tPA, further suggesti

38 ment of synthetic peptides modeled after the RACK-1-binding site in the C2 region of PKC beta induced

39 rescence and intracellular redistribution of RACK-1.

40 o isozyme-specific anchoring proteins termed RACKs, accompany protein kinase C (PKC) activation.

41 ddition to anchoring activated PKC isozymes, RACKs anchor other signaling enzymes.

42 silonPKC first translocates and binds to its RACK and subsequently the epsilonPKC/epsilonRACK complex

43 or that can be adapted to almost any kind of rack and tubes (3D files, the parts required, the electr

44 integration with Allentown NexGen ventilated racks and allows unobstructed view of up to three mice,

45 % versus 14+/-1%, control versus psi(epsilon)RACK) and resulted in fewer cases of ventricular fibrill

46 proteins (receptors for activated C kinases (RACKs)) and demonstrates a direct connection between the

47 ckground, time of year, cage location on the rack, and rack orientation in the room were significant

48 dation of the Zapotec state, the first skull rack, and the building of a fortress in conquered territ

49 The motions are akin to rack-and-pinion gears at the molecular level.

50 as torque- or velocity-amplifiers, and micro-rack-and-pinion systems that serve as microfluidic valve

51 addition, pretreatment of platelets with eta-RACK antagonistic peptides, a specific inhibitor of nPKC

52 Therefore, RACKs are not only adaptors for PKC, but also serve as a

53 onducted unobtrusive observations at bicycle racks at public elementary schools statewide.

54 Furthermore, administration of psi(epsilon)RACK before ischemia followed by deltaV1-1 during reperf

55 As expected for a PKCepsilon RACK binding peptide, confocal microscopy showed that ep

56 ypothesized that in inactive epsilonPKC, the RACK-binding site is engaged in an intramolecular intera

57 y shown that at least part of the PKCepsilon RACK-binding site on PKCepsilon lies within the unique V

58 eraction between the psiepsilonRACK site and RACK-binding site within epsilonPKC is critical and rate

59 In contrast, pretreatment with psi(epsilon)RACK but not deltaV1-1, followed by a 10-minute washout

60 s an oncologist is inherently difficult, and racked by emotional and psychological traumas.

61 d pi-stacked arrays of dimers undergo a wine-rack compression, but the dimer remains intact up to 8 G

62 epsilon-protein kinase C (PKC), psi(epsilon)RACK, conferred cardioprotection against ischemia-reperf

63 continuous systemic delivery of psi(epsilon)RACK confers sustained cardioprotection against ischemia

64 adverse effects after sustained psi(epsilon)RACK delivery.

65 We have achieved this through a 'wine rack' design where rigid pai-stacked columns of perylene

66 ns, at different levels ranging from rack-to-rack down to chip-to-chip and intra-chip interconnection

67 be a result of inhibition of its binding to RACKs due to Nef binding, could contribute to the variou

68 inistration of deltaV1-1 but not psi(epsilon)RACK during reperfusion improved cardiac function and de

69 ing of the activated isozyme to its specific RACK, epsilonRACK.

70 ng, yeasts are removed after fermentation by racking, filtration, or centrifugation, which add costs

71 ture in both redox states and extending the "rack" hypothesis to the Se-substituted protein.

72 The role of RACKs in PKC-mediated signaling was determined using iso

73 A set of tubes was constructed from the racks in this set to prevent contamination and potential

74 e at least some of the proteins that bind to RACKs, including PKC itself, regulate cell growth, modul

75 ction, continuous treatment with psi(epsilon)RACK induced a sustained preconditioned state during the

76 The epsilonPKC activator psi(epsilon)RACK induced cardioprotection both in vivo and ex vivo,

77 Whereas psi(epsilon)RACK-induced cardioprotection lasted 1 hour after a sing

78 tal (which results in a so-called entatic or rack-induced state) modifies the folding of the metallat

79 These findings reveal that the entatic/rack-induced state, governing the features of the metal

80 that the protein scaffold creates an entatic/rack-induced state, which gives rise to a rigid environm

81 translocation of PKCepsilon and PKCbetaI by RACK interference peptides attenuated EGF-mediated preve

82 RACK2, the epsilonPKC-specific RACK, is a coated-vesicle protein and thus is involved i

83 This corresponds to a "wine-rack"-like mechanism for NLC that we find also results i

84 The rack-like movement is based on expansions and compressio

85 Thus, psi(epsilon)RACK may be useful for patients with ischemic heart dise

86 l growth, modulating their interactions with RACKs may help elucidate signaling pathways leading to c

87 mate; this structural frustration implies a "rack" mechanism for the 290 mV (vs NHE) reduction potent

88 ility level is comparable to the widely used rack-mount Microchip 5071A cesium frequency standard.

89 f these lasers have only been validated with rack-mounted support equipment, assembled with fibre las

90 Due to the use of magnetic racks, multiple samples can be run simultaneously.

91 bound polypeptides by causing expansion (or racking) of some regions and compaction of others, most

92 time of year, cage location on the rack, and rack orientation in the room were significant risk facto

93 Cage ventilation and rack orientation often cannot be changed in modern vivar

94 gp120-triggered transient activation of the Rack-PAK-LIMK pathway, and that knockdown of LIMK throug

95 In addition, the psi(epsilon)RACK peptide should be a useful pharmacological agent fo

96 in human platelets pretreated with PKC-theta RACK peptide, which may contribute to the lower levels o

97 V1-1) and epsilon-PKC activator (psi(epsilon)RACK) peptides for ischemia/reperfusion damage in isolat

98 s, such as receptors for activated C kinase (RACKs), play an important role in regulating the localiz

99 Our findings indicate that INAD functions as RACK (receptor for activated PKC), allowing eye-PKC to p

100 platelets, PKC-theta-selective antagonistic (RACK; receptor for activated C kinase) peptide significa

101 ediated by their binding to isozyme-specific RACKs (receptors for activated C-kinase).

102 -selective proteins were called collectively RACKs (receptors for activated C-kinase).

103 PKC-interacting proteins collectively called RACKs (Receptors for Activated C-Kinases).

104 llowing: (i) The protein backbones (the "SOD rack") remain essentially unchanged.

105 Pad, an iPod Touch, and an Amazon Kindle), a rack server, and a network switch.

106 instructions for a standalone non-ventilated rack solution that holds three systems for more compact

107 enables users to remotely inspect the rooms, racks, tanks, and lines within a given facility.

108 r interaction with a sequence resembling its RACK, termed psiepsilonRACK.

109 onnections, at different levels ranging from rack-to-rack down to chip-to-chip and intra-chip interco

110 ge motion in a flexible framework with "wine-rack" topology.

111 psi(epsilon)RACK treatment reduced infarct size (34+/-2% versus 14+/

112 solated mouse hearts and whether psi(epsilon)RACK treatment reduces infarct size or lethal arrhythmia

113 schemia-reperfusion in vivo, and psi(epsilon)RACK was administered by intracoronary injection during

114 After psi(epsilon)RACK was systemically administered in mice either acutel

115 ithout access to Allentown NexGen ventilated racks, we provide designs and assembly instructions for

116 on V1 region to clone a PKCepsilon-selective RACK, which was identified as the COPI coatomer protein,

117 Microarchitectures of R, such as dimer racks, would effectively immobilize R but have little im

118 1 and a point mutant that does not bind Src (RACK Y246F) with green fluorescent protein and expressed