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1 th beta- and alpha-emitter radionuclides for radioimmunotherapy.
2 ion therapy followed by ibritumomab tiuxetan radioimmunotherapy.
3 cells: targeted nanospheres and pretargeted radioimmunotherapy.
4 or dose than is possible with nonpretargeted radioimmunotherapy.
5 cute leukemias administered externally or as radioimmunotherapy.
6 with antibody drug conjugates, and dosing in radioimmunotherapy.
7 tory to rituximab and either chemotherapy or radioimmunotherapy.
8 Bone marrow is usually dose-limiting for radioimmunotherapy.
9 onitor the therapeutic effect of pretargeted radioimmunotherapy.
10 harmaceuticals; 37.9% did not treat NHL with radioimmunotherapy.
11 r institution accepted Medicare patients for radioimmunotherapy.
12 ne for a more informed design of combination radioimmunotherapy.
13 tial to be more effective than standard-dose radioimmunotherapy.
14 n tumors typically drops significantly after radioimmunotherapy.
15 ng the response of non-Hodgkin's lymphoma to radioimmunotherapy.
16 ease toxicity of subsequent (131)I-rituximab radioimmunotherapy.
17 before radioimmunotherapy and at 12 wk after radioimmunotherapy.
18 brane antigen, has potential as an agent for radioimmunotherapy.
19 , such as with immunoSPECT and immunoPET, or radioimmunotherapy.
20 L) after treatment with ibritumomab tiuxetan radioimmunotherapy.
21 -Fc H310A/H435Q as a promising candidate for radioimmunotherapy.
22 NHL and 1.9 years (range, 0.4 to 6.3) after radioimmunotherapy.
23 ith multistep immune targeting approaches to radioimmunotherapy.
24 phoma has led to a resurgence of interest in radioimmunotherapy.
25 arted induction treatment; 57 (80%) received radioimmunotherapy.
26 ionuclides, as currently practiced in cancer radioimmunotherapy.
27 rter residence time that limits their use in radioimmunotherapy.
28 ecules can be used as effective vehicles for radioimmunotherapy.
29 xamined in patients with lymphoma treated by radioimmunotherapy.
30 3, and J591) and their potential utility for radioimmunotherapy.
31 targeting may be involved in the success of radioimmunotherapy.
32 e myeloid leukaemia 5 months after receiving radioimmunotherapy.
33 otherapeutically enhanced hK2 targeted alpha-radioimmunotherapy.
34 Analyses included only patients who received radioimmunotherapy.
35 ostic and radiotherapeutic agents for PET or radioimmunotherapy.
36 ive of improved PFS after (131)I-tositumomab radioimmunotherapy.
37 he clinically emerging method of pretargeted radioimmunotherapy.
38 linical biodistribution studies and clinical radioimmunotherapies.
39 was performed on 13 patients at 24 wk after radioimmunotherapy, 12 of whom did not receive interval
40 diagnosed with tMDS/tAML prior to receiving radioimmunotherapy; 2 (8%) had no pathologic or clinical
41 108 lesions evaluated at 12 and 24 wk after radioimmunotherapy, 49 resolved at 12 wk and remained re
43 6 received autologous HCT 3 d after (211)At-radioimmunotherapy, after lymph node and bone marrow bio
44 oal of this work was to determine an optimal radioimmunotherapy agent for further development against
45 p53-negative tumor-bearing mice treated with radioimmunotherapy alone or combined with cisplatin show
46 HCT116 tumor-bearing mice, receiving either radioimmunotherapy alone or in combination with cisplati
47 ately 30% of its maximum tolerated dose, and radioimmunotherapy alone, at its maximum tolerated dose,
52 ty-six patients received full-radiation-dose radioimmunotherapy and 12 received attenuated doses beca
53 0) and underwent 18F-FDG PET/CT scans before radioimmunotherapy and at 12 wk after radioimmunotherapy
55 -PD-L1 antibody for radionuclide imaging and radioimmunotherapy and highlight a new opportunity to op
56 In this study, we used EGFR as a target for radioimmunotherapy and hypothesized that EGFR-directed r
59 ysplastic syndrome 28 months after receiving radioimmunotherapy and one patient developed acute myelo
62 vivo purging with rituximab, the utility of radioimmunotherapy and, finally, the evolving strategy o
63 esponse in two (both treated with additional radioimmunotherapy) and a mixed response in the remainin
64 ed systems, lessons learned from pretargeted radioimmunotherapy, and important considerations for har
67 hese larger formats may be more suitable for radioimmunotherapy applications, evidenced by the precli
69 ive allogeneic transplantation and high-dose radioimmunotherapy are topics of ongoing investigation.
72 toxicity is highly unlikely in standard dose radioimmunotherapy but should be considered a potential
74 es could potentially play a valuable role in radioimmunotherapy by more stably encapsulating radionuc
75 ates the opinions and patterns of the use of radioimmunotherapy by nuclear physicians, affiliated res
76 the potential for improving the efficacy of radioimmunotherapy by targeting other NHL cell surface a
77 ctivity retained in the body after high-dose radioimmunotherapy can damage PBSCs if they are transfus
78 otherapy and hypothesized that EGFR-directed radioimmunotherapy can deliver a continuous lethal radia
80 re eradicated in mice treated with anti-EGFR radioimmunotherapy combined with chemotherapy and PARP i
83 success of antibody-based immunotherapy and radioimmunotherapy directed at single targets (eg, GD2 a
85 y (mAb; CA12.10C12) protein dose for (211)At-radioimmunotherapy, extending the analysis to include in
87 lenge, rendering (225)Ac@GNTs candidates for radioimmunotherapy for delivery of (225)Ac(3+) ions at h
88 nt the efficacy and decrease the toxicity of radioimmunotherapy for disseminated murine leukemia.
89 le and 13 female; median age, 64 y) received radioimmunotherapy for NHL (20 received (90)Y-ibritumoma
93 of targeted monoclonal antibody therapy and radioimmunotherapy for orbital and adnexal non-Hodgkin's
94 antibody 8H9 has been successfully used for radioimmunotherapy for patients with B7-H3(+) tumors.
96 n lymphoma patients after (131)I-tositumomab radioimmunotherapy for potential use in treatment planni
97 viously treated patients, and 4.6 years from radioimmunotherapy for previously untreated patients.
100 mbination therapies using systemic anti-EGFR radioimmunotherapy for the treatment of recurrent and me
101 eview will present the latest information on radioimmunotherapy for treatment of hematologic malignan
102 c information useful for titrating doses for radioimmunotherapy, for patient risk stratification and
103 m baseline in 244 target lesions 12 wk after radioimmunotherapy (from 6.51+/-4.05 to 3.94+/-4.41; P<0
105 em-cell transplant or myeloablative doses of radioimmunotherapy given in conjunction with stem-cell s
106 owed delayed tumor growth in the pretargeted radioimmunotherapy group, corresponding with their prolo
107 d consolidation as a possible indication for radioimmunotherapy had significantly fewer concerns abou
108 ividuals who perceived a negative future for radioimmunotherapy had significantly more concerns about
115 therapies, both unconjugated antibodies and radioimmunotherapy, have had a significant impact on the
116 ioimmunotherapy predicted a higher growth of radioimmunotherapy if they could administer it in their
118 an intravenous fractionated regimen of alpha-radioimmunotherapy in a subcutaneous tumor model in mice
119 In this first preclinical study of anti-EGFR radioimmunotherapy in breast cancer, we found that anti-
120 n vivo purging with rituximab and the use of radioimmunotherapy in conditioning regimens may further
121 ficacy with the combination of cetuximab and radioimmunotherapy in CRC, which could potentially trans
122 ovide a foundation for maximising the use of radioimmunotherapy in disease control, designing future
123 role of kinetic and transport parameters of radioimmunotherapy in maximizing the therapeutic ratio,
125 atuzumab tetraxetan ((90)Y-DOTA-epratuzumab) radioimmunotherapy in refractory or relapsed CD22-positi
129 nical trials and reinvigorate enthusiasm for radioimmunotherapy in the treatment of malignancies, par
131 on make tomoregulin an attractive target for radioimmunotherapy, in which tomoregulin-specific antibo
132 scientific concerns, barriers to the use of radioimmunotherapy included difficulty in referral, perc
133 White blood cell count analysis after alpha-radioimmunotherapy indicated bone marrow recovery for th
137 w (RM) is often the primary organ at risk in radioimmunotherapy; irradiation of marrow may induce sho
143 py in breast cancer, we found that anti-EGFR radioimmunotherapy is safe and that TNBC orthotopic tumo
145 table response rates have been observed when radioimmunotherapy is used as front-line treatment in pa
147 directed RLT (in combination with additional radioimmunotherapy) is feasible as a conditioning regime
150 Cytogenetic testing before treatment with radioimmunotherapy may identify existing chromosomal abn
153 t of these bsRICs for dual-receptor-targeted radioimmunotherapy of BC coexpressing HER2 and EGFR, inc
156 mply that the optimal strategy for A33-based radioimmunotherapy of colon cancer will consist of a mul
159 the absorbed dose (AD) to the artery wall in radioimmunotherapy of NHL is of potential concern for de
167 tibody that pretargeted (90)Y-hapten-peptide radioimmunotherapy or a directly radiolabeled, humanized
168 lymphoma and can be used in combination with radioimmunotherapy or standard chemotherapy for a more d
170 thought it took too much time to administer radioimmunotherapy (P < 0.01) and had concerns about the
174 Finally, the 3D methods were applied to a radioimmunotherapy patient, and the mean tumor absorbed
175 efficacy and safety of anti-CEA pretargeted radioimmunotherapy (pRAIT) in rapidly progressing metast
177 with a positive outlook about the future of radioimmunotherapy predicted a higher growth of radioimm
178 report a theranostic approach to pretargeted radioimmunotherapy (PRIT) based on a pair of radioisotop
179 We now show the superiority of pretargeted radioimmunotherapy (PRIT) compared with conventional rad
183 recently reported a novel 3-step pretargeted radioimmunotherapy (PRIT) strategy based on a glycoprote
190 ies alone or in combination with pretargeted radioimmunotherapy (PT-RAIT) or radioimmunotherapy, and
192 safety, and clinical activity of radretumab radioimmunotherapy (R-RIT) were evaluated in 18 relapsed
193 improved therapeutic index with pretargeted radioimmunotherapy (RAIT) using a DNL-constructed tri-Fa
194 w that anti-GPA33 DOTA-PRIT will be a potent radioimmunotherapy regimen for GPA33-positive colorectal
199 s the most current allogeneic HCT data using radioimmunotherapy (RIT) and focuses on recent trials in
204 was 6 years from diagnosis and 2 years from radioimmunotherapy (RIT) for previously treated patients
206 e treatment of non-Hodgkin's lymphoma (NHL), radioimmunotherapy (RIT) has finally come of age as a ne
207 ry radiosensitive, but the potential role of radioimmunotherapy (RIT) in the management of plasmacyto
208 (375 mg/m(2)) and proceeded to fractionated radioimmunotherapy (RIT) only if a repeat BM biopsy demo
211 d a conditioning regimen employing anti-CD45 radioimmunotherapy (RIT) replacing total body irradiatio
213 anti-DR) antibodies (Abs) and of pretargeted radioimmunotherapy (RIT) using Ab-streptavidin (SA) conj
216 ium-90 (Y-90) ibritumomab tiuxetan (Zevalin) radioimmunotherapy (RIT) was safe and effective for rela
217 S-17 tumor-bearing SCID mice and followed by radioimmunotherapy (RIT) with 177Lutetium-2G11 and safet
220 targeting and tumor control by CD20-directed radioimmunotherapy (RIT), but had no impact on targeting
221 ed with either external beam radiotherapy or radioimmunotherapy (RIT), which joins the selectivity of
225 An antibody-targeted radiation therapy (radioimmunotherapy, RIT) employs a bifunctional ligand t
226 als are currently underway to further define radioimmunotherapy's role in the treatment of lymphomas.
229 d with monotherapy, combining cetuximab with radioimmunotherapy significantly and synergistically red
230 Results: (225)Ac-labeled DOTAylated-huCC49 radioimmunotherapy significantly reduced tumor growth in
234 inal half-life and serum clearance suited to radioimmunotherapy (T1/2beta, 100.24 +/- 20.92 h, and cl
236 d comparative assessments using conventional radioimmunotherapy targeting CD20, CD22, and HLA-DR on h
238 meters and may be particularly effective for radioimmunotherapy targeting minimal residual disease (M
241 derable success in improving the efficacy of radioimmunotherapy, the pretargeting strategy remains un
242 dies targeting lymphoma-associated antigens, radioimmunotherapy, therapeutic vaccination and allogene
244 e tumor absorbed radiation doses in STI571 + radioimmunotherapy-treated mice compared with PBS + radi
251 unotherapy (PRIT) compared with conventional radioimmunotherapy using a recombinant tetravalent singl
255 assess activity and toxicity of fractionated radioimmunotherapy using anti-CD22 (90)Y-epratuzumab tet
256 eutic efficacy of beta- versus alpha-emitter radioimmunotherapy using radiolabeled DOTA-daratumumab i
258 ated the preclinical efficacy of combination radioimmunotherapy, using a humanized (131)I-labeled ant
259 bolic activity was assessed before and after radioimmunotherapy visually and quantitatively by lean m
262 n percentage decline in platelet count after radioimmunotherapy was greater in the (90)Y-ibritumomab
264 ed survey with 13 broad questions related to radioimmunotherapy was sent electronically to 13,221 Soc
265 various sizes after intraperitoneal (211)At-radioimmunotherapy, we used an in-house-developed Monte
266 emarkable improvements in tumor responses to radioimmunotherapy were discovered after the inclusion o
270 this study was to determine the efficacy of radioimmunotherapy when using (90)Y-labeled cetuximab an
271 trials have shown the promise of pretargeted radioimmunotherapy, which leverages the specificity of a
273 umor-to-red marrow dose ratio was higher for radioimmunotherapy with (177)Lu-cG250 than for radioimmu
277 cts on tumor growth after fractionated alpha-radioimmunotherapy with (211)At-MX35-F(ab')2 was strong
278 cts on tumor growth after fractionated alpha-radioimmunotherapy with (211)At-MX35-F(ab')2 was strong
281 e examine the role of p53 in the response to radioimmunotherapy with (64)Cu-DOTA-cetuximab in KRAS-mu
282 dioimmunotherapy with (177)Lu-cG250 than for radioimmunotherapy with (90)Y-cG250, indicating that (17
289 This clinical trial evaluated standard-dose radioimmunotherapy with a chemotherapy-based transplanta
291 ternal gamma-beam radiation, we investigated radioimmunotherapy with an anti-CD45 mAb labeled with th
292 a dose of 2 mCi/kg Bi, further trials using radioimmunotherapy with Bi for nonmyeloablative HCT seem
293 study demonstrates that dose deescalation of radioimmunotherapy with Bi labeled to anti-CD45 or anti-
295 the authors demonstrated that pretransplant radioimmunotherapy with the alpha-emitter bismuth-213 (B
296 R could be treated by dual-receptor-targeted radioimmunotherapy with these bsRICs labeled with the be
297 he limitations of conventional, or one-step, radioimmunotherapy, with initial preclinical and clinica
298 Almost 30% (29.6%) of the responders thought radioimmunotherapy would probably grow and 38.0% thought
299 Seventy-nine (36.6%) responders thought radioimmunotherapy would probably grow in importance, an