ライフサイエンスコーパス: radiolabel

1 addition, these drugs are relatively easy to radiolabel.

2 yed for in vitro binding affinities and then radiolabeled.

3 aceuticals and practical synthesis for (18)F-radiolabeling.

4 ting new chelators and prosthetic groups for radiolabeling.

5 ewed-like extraction was studied using (14)C-radiolabeled ((14)C-AA) and (13)C-labeled ((13)C(3)-AA)

6 Studies with doubly radiolabeled 16 provide a proof-of-concept for the use o

7 nce of molecular imaging (MI), championed by radiolabeled (18)F-FDG PET, has expanded the information

8 Both constructs rapidly radiolabeled (225) Ac in just minutes at RT, and macropa

9 The uptake of radiolabeled 28H1 in inflamed joints (percentage injecte

10 Liposomes were efficiently radiolabelled (57%) within 1 h, with release of ~12% of

11 Results: The radiolabeled (64)Cu-PSMA ligands showed high serum stabi

12 This yielded radiolabeled [(64)Cu]-NPs of uniform shape and size with

13 Conclusion: We have successfully radiolabeled 6R- and 6S-3'-aza-2'-(18)F-fluoro-5-MTHF wi

14 We radiolabeled a dendritic galactose carbohydrate with (18

15 Concomitant administration of an oral C radiolabeled acetaminophen microtracer (3 ng/kg) with IV

16 Here we present two methods for radiolabeling adeno-associated virus (AAV), one of the m

17 d into a protocol for the synthesis of (18)F-radiolabeled aliphatic CF3-containing compounds, enablin

18 lically labeling large numbers of cells with radiolabeled amino acids or amino acid analogs.

19 demonstrated good agreement with established radiolabelled amino acid incorporation assays: TGFbeta1

20 r of T-cell activation that can be imaged by radiolabeling an anti-ICOS antibody and performing PET s

21 A radiolabeled analog, [(125) I]-PD-sauvagine, with high s

22 of the macropa chelator enabled quantitative radiolabeling and may facilitate the clinical translatio

23 Methods: Simultaneous (89)Zr-radiolabeling and protein conjugation was performed in o

24 Subsequent radiolabelling and in vivo PET imaging experiments in a

25 Here, we use electrophysiological, radiolabeled, and fluorescence-based transport assays in

26 )Zr-DFO-AMG102 was successfully synthesized, radiolabeled, and validated in vitro and in vivo to sele

27 and fluorescence, calcium imaging, phosphate radiolabeling, and a beta-arrestin-dependent luciferase

28 rapid amplification of cDNA ends (RACE), 5' radiolabeling, and exonuclease digestion, which revealed

29 ards, different isotope labeling strategies, radiolabeling, and predicted ionization efficiencies are

30 the significantly higher tumor uptake of the radiolabeled antagonist than of the agonist as measured

31 Two "first-generation," directly radiolabeled anti-CD20 antibodies, (131)iodine-tositumom

32 he aim of this study was to assess whether a radiolabeled anti-FAP antibody could be used to monitor

33 ume in mice can be measured by PET-CT with a radiolabeled anti-PD-L1 antibody.

34 ied only in experimental animals, except for radiolabeled antibiotics, which have been examined in hu

35 Methods that provide rapid access to radiolabeled antibodies are vital in the development of

36 le alternative approach for producing (89)Zr-radiolabeled antibodies directly in protein formulation

37 Using radiolabeled antibodies or fragments derived from them,

38 dies demonstrate the ability to image (89)Zr-radiolabeled antibodies up to 30 d after injection while

39 Immunoreactive preparations of the radiolabeled antibodies were injected into NCr nu/nu mic

40 Radioimmunotherapy, an approach using radiolabeled antibodies, has had minimal success in the

41 The use of radiolabeled antibodies, immunoglobulin fragments, and o

42 Radiolabeled antibodies, such as (131)I-omburtamab direc

43 Radiolabeled antibody accumulation in patient-derived xe

44 n the biodistribution and biokinetics of the radiolabeled antibody and to investigate differences bas

45 Conclusion: (111)In-DOTA-5D3 is a new radiolabeled antibody for imaging and a surrogate for th

46 Positron electron tomography imaging using radiolabeled antibody recognizing TREM1 revealed elevate

47 Here, we evaluated (64)Cu-rituximab, a radiolabeled antibody specifically targeting the human B

48 ng PDX and commercial OS tumors in mice with radiolabeled antibody to IGF2R and to investigate IGF2R

49 njugation, providing a promising alternative radiolabeling approach that maintains the native in vivo

50 Our direct radiolabeling approach, allows for immediate screening o

51 Here, we develop a radiolabeling assay and use stopped-flow kinetics to est

52 monstrate such a method using PET imaging of radiolabeled bevacizumab.

53 Radiolabeled bisphosphonates such as (99m)Tc-3,3-diphosp

54 igen (PSCA) cys-diabody A2, and subsequently radiolabeled by click chemistry with (18)F-TCO.

55 Here we develop a radiolabeled camelid single-domain antibody (anti-PD-L1

56 Finally, droplets encapsulating radiolabeled cancer cells allowed, for the first time, t

57 Radiolabeled cancer-seeking agents, however, undergo deg

58 Selected radiolabeled candidates were evaluated in vitro and in v

59 , CdWO4) is placed in close proximity to the radiolabeled cells, where it converts the radioactive de

60 cular imaging and targeted radiotherapy with radiolabeled cholecystokinin-2 receptor (CCK2R) targetin

61 mor explants for studies of incorporation of radiolabeled choline into phospholipids and its contribu

62 nt imaging properties but greatly simplified radiolabeling compared with other (68)Ga-PSMA conjugates

63 Using crystallographic approaches and radiolabeled competitive binding-capacity assays, we rep

64 In theranostics, radiolabeled compounds are used to determine a treatment

65 and the in vivo characterization of the main radiolabeled compounds confirmed that, except for (64)Cu

66 rmined to prove whether the stability of the radiolabeled compounds is sufficient to ensure no signif

67 d of microfluidics to synthesize short-lived radiolabeled compounds.

68 le measurement of the emitted radiation from radiolabeled compounds.

69 half-times and higher liver uptake than the radiolabeled counterparts.

70 Molecular imaging with recently developed radiolabeled CXCR4 ligands could facilitate the selectio

71 We aimed to develop a radiolabeled cyclin-dependent kinase 4/6 (CDK4/6) inhibi

72 tently and equally suppressed the release of radiolabelled d-[(14) C]aspartate and [(3) H]taurine.

73 characterization of a M2R subtype-preferring radiolabeled dibenzodiazepinone-type antagonist ([(3)H]U

74 ersus alpha-emitter radioimmunotherapy using radiolabeled DOTA-daratumumab in a preclinical model of

75 Radiolabeled drug quantified bulk delivery and fluoresce

76 PET imaging with radiolabeled drugs provides information on tumor uptake

77 the study of small-molecule transport (e.g., radiolabeled drugs, metabolic precursors and nuclear med

78 imental approach using phosphorus-32 ((32)P)-radiolabeled dsRNA that allows studying key fate process

79 5 degrees C for 2h) of (52)Mn gave excellent radiolabeling efficiencies of 97-100% and 98-100% respec

80 and prohibits the therapeutic application of radiolabeled exendin for beta-cell-derived tumors.

81 ike peptide 1 receptor (GLP-1R) imaging with radiolabeled exendin has proven to be a powerful tool to

82 to GLP-1R agonist treatment or quantitative radiolabeled exendin imaging for BCM analysis.

83 ofusine) to reduce the renal accumulation of radiolabeled exendin in humans, and we performed dosimet

84 ate qualitative and quantitative analyses of radiolabeled exendin uptake in the tail region of the pa

85 (55)Fe-radiolabeling experiments with human cells depleted of C

86 Using co-immunoprecipitation and (55)Fe-radiolabeling experiments, we therefore studied the role

87 experimentally confirmed by two independent radiolabeling experiments.

88 for quantitative metabolite profiling, i.e., radiolabeling followed by high-performance liquid chroma

89 ration, and pathways were monitored by (14)C-radiolabelling followed by high-voltage electrophoresis.

90 Here, we used a (111)In-radiolabeled form of LF with the PA/LF system for noninv

91 However, although a radiolabelled form of a related antagonist, [(3)H]G9543,

92 n: Taken together, our results indicate that radiolabeled forms of mutated anthrax lethal toxin hold

93 x by 80-90%, as monitored by the transfer of radiolabel from [(35)S]methionine to GSH.

94 The use of radiolabeled gastrin analogs targeting the cholecystokin

95 functional studies included incorporation of radiolabeled Glc, linkage analysis, and imaging of cellu

96 gnosis, localization, and treatment with the radiolabeled GLP-1R agonist exendin.

97 rinsulinemic-euglycemic clamps combined with radiolabeled glucose to assess liver and muscle insulin

98 After the FUS treatment, radiolabeled gold nanoclusters, (64)Cu-AuNCs, were intra

99 vivo and in vitro labeling experiments using radiolabeled GPI precursors showed that GPI underglycosy

100 overexpressed in human prostate cancer, and radiolabeled GRPr affinity ligands have shown promise fo

101 nnocuous, appending nanoparticles with these radiolabeling handles can have dramatic effects on impor

102 Here, we have used a (89)Zr-radiolabeled human CD8-specific minibody ((89)Zr-Df-IAB2

103 Tumor uptake of the radiolabeled, humanized anti-GD2 antibody [(64)Cu]Cu-Bn-

104 Therefore, we developed 2 radiolabeled IL2 variants, namely aluminum (18)F-fluorid

105 lography and validate leads with 3 different radiolabels in pre-clinical models of cancer.

106 ter conjugation to a DFO chelator and (89)Zr radiolabeling, in assays including cell uptake, internal

107 The position of the radiolabel influences targeting as well, although to a l

108 Imaging of PARP using a radiolabeled inhibitor has been proposed for patient sel

109 This is further supported by transfer of radiolabels into product from both alpha and gamma phosp

110 he utility of the process in enabling (18) F-radiolabeling is also presented.

111 Despite these rapid developments, (89)Zr radiolabeling is still performed manually.

112 the first time (to our knowledge), the (18)F-radiolabeled isotopolog of the Food and Drug Administrat

113 by conjugating A9 with the DTPA chelator and radiolabeling it with (111)In.

114 n emission tomography (PET) TrkB/C-targeting radiolabeled kinase inhibitor lead.

115 erexpression of LAT in many types of cancer, radiolabeled LAT substrates are promising candidates for

116 nowledge, this is the first demonstration of radiolabeled lipophilic cations being used for the PET i

117 We report optimized protocols for radiolabeling liposomes with (52)Mn, through both remote

118 ed the kinetics of intraperitoneally infused radiolabeled mAbs in humans and showed the benefit of in

119 hich also allows the GMP production of other radiolabeled mAbs.

120 ine) of solids T1/2 (time taken for half the radiolabelled meal to empty from the stomach), measured

121 high specific activities (50-99 Ci/mmol) in radiolabeling, meeting the threshold required for radiol

122 Radiolabeled meta-iodobenzylguanidine (mIBG) is an impor

123 In separate groups of mice, radiolabeled metabolites of (11)C-metoclopramide were de

124 r, there is a dearth of efficient and simple radiolabeling methods for aromatic C-H bonds, which limi

125 generated a range of innovative chelate-free radiolabeling methods that exploit intrinsic chemical fe

126 HCC cells from Apc(ko-liv) mice incorporated radiolabeled methyl groups of choline into phospholipids

127 Thus, radiolabeled MG11 derivatives have great potential for u

128 the safety and utility of (89)Zr-IAB22M2C, a radiolabeled minibody against CD8+ T cells, for targeted

129 omising target for the treatment of MTC with radiolabeled minigastrin analogs.

130 This approach can be established using radiolabeled MMP inhibitors (MMPIs) as tracers for the d

131 Radiolabeled molecular imaging tracers directed toward c

132 We systematically screened 961 random radiolabeled molecules in silico as substrates for essen

133 ine concerned with the use of radioisotopes, radiolabelled molecules, nanoparticles, or microparticle

134 To bridge this gap, we site-specifically radiolabeled mono- (scFv) and bivalent (mAb) affinity li

135 Intraperitoneally administered radiolabeled monoclonal antibodies (mAbs) have been test

136 ay be useful in immuno-PET radiochemistry as radiolabeled monoclonal antibodies are increasingly inte

137 Therapy of cancer with radiolabeled monoclonal antibodies has produced impressi

138 Fluorescent and radiolabeled MSCs (1x10(6)) were injected 24 hours post-

139 Comparative work with an equipotent radiolabeled MT1-MMP targeting antibody demonstrated sta

140 Biodistribution studies of radiolabeled multi-triazolo-peptidomimetics in mice bear

141 Radio-nanomedicine, or the use of radiolabeled nanoparticles in nuclear medicine, has attr

142 Classic methods for radiolabeling nanoparticles involve functionalization of

143 ry of 9 mechanistically distinct methods for radiolabeling nanoparticles is presented.

144 We aimed to determine whether radiolabeled NPs could be used as a noninvasive, highly

145 Radiolabeled NT3 crossed from the bloodstream into the b

146 A gel shift assay with a radiolabeled OARE module and nuclear extracts prepared f

147 e receptor radionuclide therapy (PRRT) using radiolabeled octreotate is an effective treatment for so

148 Methods: Radiolabeling of (18)F-AlF-RESCA-IL2 and (68)Ga-Ga-NODAG

149 e, 1-step, room-temperature syringe-and-vial radiolabeling of (68)Ga radiopharmaceuticals.

150 ion-reconstruction approach to the carbon-14 radiolabeling of alkyl carboxylic acids is presented.

151 Our method does not require radiolabeling of any components and therefore can be use

152 This paper describes the radiolabeling of biotin with the positron emission tomog

153 ctivity (22 +/- 4 Mbq/nmol) suitable for the radiolabeling of DOTA-conjugated vectors.

154 evaluates the use of (89)Zr-chloride in the radiolabeling of monoclonal antibodies conjugated with d

155 Radiolabeling of MSB0010853 with (89)Zr was performed wi

156 development of these modalities through the radiolabeling of somatostatin analogs with various radio

157 The TF-targeted tracer was developed through radiolabeling of the anti-human TF monoclonal antibody (

158 Radiolabeling of the prostate-specific membrane antigen

159 These findings present a novel radiolabeled oligonucleotide for targeting telomerase-po

160 study indicates the therapeutic activity of radiolabeled oligonucleotides that specifically target h

161 report the synthesis and characterization of radiolabeled oligonucleotides that target the RNA subuni

162 (PSMA)-targeting characteristics of PSMA-11, radiolabeled on the basis of chelation of (18)F-AlF, wit

163 hotoradiochemical approach to produce (89)Zr-radiolabeled onartuzumab (a monovalent, antihuman c-MET

164 Uptake of (111)In-radiolabeled PA-L1, (111)In-PA-WT(K563C), or (111)In-LF(

165 acid oxidation in primary hepatocytes using radiolabeled palmitate and in mice using indirect calori

166 the pharmacokinetics and biodistribution of radiolabeled pembrolizumab in vivo, while providing deta

167 e of the study was to analyze the ability of radiolabeled pentixafor to detect CXCR4 expression on in

168 Conclusion: Therapy with radiolabeled pentixather appears to be well tolerated an

169 suboptimal targeting of currently available radiolabeled peptide analogs has prompted us to seek new

170 Using pulse-chase radiolabeling, peptide-N-glycosidase F treatment, lectin

171 hts the advances of MC1R- and VLA-4-targeted radiolabeled peptides and peptide-conjugated C' dots for

172 croenvironment that was detectable using the radiolabeled pH (low) insertion peptide (pHLIP).

173 A radiolabeled pH-targeted peptide can be used as a PET im

174 Methods: Using a radiolabeled poly(ADP-ribose) polymerase (PARP) inhibito

175 Here, using biochemical and radiolabeled precursor experiments, we found that partia

176 e not inhibiting DNA biosynthesis using (3)H-radiolabeled precursors in macromolecular synthesis inhi

177 New radiolabeled probes for positron-emission tomography (PE

178 tion binding experiments in competition with radiolabelled probes, followed by analysis with the wide

179 r potentially nucleophilic residues, and the radiolabeled products were synthesized and purified in l

180 PET using radiolabeled prostate-specific membrane antigen (PSMA) i

181 Radiolabeled prostate-specific membrane antigen (PSMA) P

182 Quantitative evaluation of radiolabeled prostate-specific membrane antigen (PSMA) P

183 Since the introduction of radiolabeled prostate-specific membrane antigen (PSMA) P

184 tion of radioligands(2), yet there exist few radiolabelling protocols for the synthesis of either, in

185 e patients with BCP after RARP who underwent radiolabeled PSMA PET/CT imaging were retrospectively ev

186 , diagnostic accuracy is largely lacking for radiolabeled PSMA PET/CT in patients with biochemical pe

187 Binding of radiolabeled pyruvate was found for full-length YehU in

188 ugh brain PET scans of monkeys injected with radiolabeled recombinant human LCN2 (rh-LCN2) and autora

189 ers, but irrespective of the particle class, radiolabeling remains a key step.

190 Methods:(11)C-radiolabeled sarcosine was tested as a new PET imaging p

191 ed in patients with diarrhea by retention of radiolabeled selenium-75 homocholic acid taurine.

192 trated by its use in an industrial carbon-14 radiolabeling setting.

193 er for imaging PSMA expression that could be radiolabeled simply by addition of (68)Ga generator elua

194 ctive decays occurring stochastically within radiolabeled single-cells into an integrated, long-lasti

195 rting of single cells based on the uptake of radiolabeled small molecules.

196 A radiolabeled small-molecule GPR44 antagonist, [(11)C]AZ1

197 atum corneum exposed to aqueous solutions of radiolabeled sodium chloride, tetraethyl ammonium bromid

198 Radiolabeled somatostatin (sst) receptor agonists are in

199 preliminary clinical evidence indicates that radiolabeled somatostatin (sst) receptor antagonists per

200 Moreover, the recent approval of the radiolabeled somatostatin analog (177)Lu-DOTATATE has ha

201 eatment of neuroendocrine tumors (NETs) with radiolabeled somatostatin analogs represent a milestone

202 (68)Ga-DOTATOC and (68)Ga-DOTATATE are radiolabeled somatostatin analogs used for the diagnosis

203 peptide receptor radionuclide therapy using radiolabeled somatostatin analogs.

204 e receptor radionuclide therapy (PRRT) using radiolabeled somatostatin receptor (SSTR) analogs is a c

205 Radiolabeled somatostatin receptor (SSTR) antagonists ha

206 up the opportunity to treat the patient with radiolabelled somatostatin analogs, which successfully c

207 r QNB or NMS slow down dissociation of their radiolabeled species from all five subtypes of muscarini

208 We also found evidence suggesting that the radiolabeled SPIONs produced up to a six-fold increase i

209 )-dAph(Cbm)-Lys-Thr-Cys)-dTyr-NH2)), a novel radiolabeled sst receptor antagonist with a high affinit

210 Furthermore, binding of the radiolabeled SSTR agonist and antagonist was analyzed in

211 f peptide receptor radionuclide therapy with radiolabeled sstr agonists, such as [(90)Y-DOTA(0),Tyr(3

212 iscuss the development and current status of radiolabeled sstr antagonists.

213 Methods: Radiolabeling, stability, cell uptake, and internalizati

214 Radiolabeling studies showed that macropa, at submicromo

215 Here, we describe a general method for using radiolabeled substrate flux assays to determine coupling

216 or 62% 15 R, respectively, determined using radiolabeled substrate or LC-MS analysis).

217 sociations of SLC2A14 with IBD.The uptake of radiolabeled substrates into Xenopus laevis oocytes expr

218 Using radiolabeled synTacs loaded with the appropriate peptide

219 lecular imaging of PARP using fluorescent or radiolabeled tags has followed on the success of therape

220 synthetic biology approaches, biochemistry, radiolabeling techniques, and NMR and MS analyses, we ex

221 We showed by dynamic protein radiolabeling that LLO synthesis was growth phase-depend

222 Here, we developed a protocol to directly radiolabel the virus for rapid and sensitive detection b

223 We have radiolabeled the PD-L1-binding Affibody molecule NOTA-ZP

224 B0010853 biodistribution and tumor uptake by radiolabeling the Nanobody construct with (89)Zr.

225 ions, we synthesized a series of candidates, radiolabeled them with fluorine-18 radioisotope, and det

226 Radiolabeling to produce (18)F-SO3F(-) was simple and af

227 highly selective CB2R inverse agonist, as a radiolabeled tool compound.

228 Moreover, we demonstrate how radiolabeled tracers and extracellular flux analyses int

229 Here, we used magnetic resonance imaging, radiolabeled tracers, and multiphoton imaging in rodents

230 To address these issues, we have developed a radiolabeled trametinib and evaluated the in vitro and i

231 Fluorine-18 radiolabeling typically includes several conserved steps

232 LDL induced the efflux of radiolabeled UC from cultured macrophages, and, in the s

233 ous presence of HDL, a rapid transfer of the radiolabeled UC from HDL to LDL occurred.

234 Radiolabel uptake in prominent lesions was measured as S

235 pling partners, make it amenable for in vivo radiolabelling using pretargeting methodologies, which a

236 A URAT1 binding assay using radiolabeled verinurad revealed that distinct URAT1 inhi

237 rgeted imaging of alpha V beta 3 activity (a radiolabeled version, (64)Cu-NOTA-PEG4-cRGD2, for PET im

238 Azide functionalized NPs were radiolabeled via a "click" reaction with copper-64 ((64)

239 (18)F-JNJ-64413739 was radiolabeled via a one-step nucleophilic aromatic substi

240 cally conjugated with either DML or sCy5 and radiolabeled via click chemistry with (18)F-TCO.

241 Methods: (11)C-LSN3172176 was radiolabeled via the Suzuki-Miyaura cross-coupling metho

242 e prosthetic group), and rapid and efficient radiolabeling via click chemistry with (18)F-labeled tra

243 Results: Radiolabeling was accomplished successfully with an inco

244 Radiolabeling was complete (>95%) within 5 min at room t

245 ) as a suitable radioligand lead, which upon radiolabeling was found to exhibit a high level of MAGL

246 ectrospray ionization-mass spectrometry, and radiolabeling was monitored by instant thin-layer chroma

247 hrough development of a [(3)H]levocetirizine radiolabel, we find that the residence time of 1 exceeds

248 sion tomography/computed tomography (CT) and radiolabeled white blood cells single photon emission CT

249 These candidates were then radiolabeled with (11)C and studied in vivo in rhesus mo

250 n barrier penetration, and the ability to be radiolabeled with (11)C.

251 Results: DOTA-MGS5 radiolabeled with (111)In and (177)Lu showed a highly in

252 ly-Trp-(N-Me)Nle-Asp-1-Nal-NH(2) (DOTA-MGS5) radiolabeled with (111)In, (68)Ga, and (177)Lu was evalu

253 munoconjugates were conjugated with DOTA and radiolabeled with (111)In.

254 combined, and the resulting derivatives were radiolabeled with (177)Lu and evaluated by SPECT/CT imag

255 tumor-targeting alkylphosphocholine (NM600) radiolabeled with (177)Lu for targeted radionuclide ther

256 OF-NB1, which outperformed MF-NB1, was radiolabeled with (18)F to afford (18)F-OF-NB1 in more t

257 ds: 6R-(18)F-1, 6S-(18)F-1, and (18)F-2 were radiolabeled with (18)F using aromatic nucleophilic subs

258 onjugated to bifunctional maleimide-NO2A and radiolabeled with (64)Cu (half-life, 12.7 h).

259 The scFv-Fc-CD44 was radiolabeled with (64)Cu and (89)Zr.

260 An NKp30 antibody was radiolabeled with (64)Cu or (89)Zr and evaluated in subc

261 When radiolabeled with (64)Cu or (89)Zr, it demonstrated spec

262 luate novel AD diagnostic agents that can be radiolabeled with (64)Cu, a radionuclide with a half-lif

263 DOTA-alendronate was synthesized, radiolabeled with (64)Cu, and administered to normal or

264 NeoBOMB1 was radiolabeled with (67/68)Ga, (111)In, and (177)Lu accord

265 PSMA affinity and albumin affinity and were radiolabeled with (68)Ga and (177)Lu.

266 rea-based PSMA inhibitor was synthesized and radiolabeled with (68)Ga by adding generator eluate dire

267 Methods: NM600 was radiolabeled with (86)Y for PET imaging and (177)Lu for

268 ecific Affibody molecule (Z(EGFR:03115)) was radiolabeled with (89)Zr and (18)F.

269 implex viral protein glycoprotein D (gD) was radiolabeled with (89)Zr via 1 of 4 chelator-linker comb

270 onjugated with deferoxamine and subsequently radiolabeled with (89)Zr.

271 tuzumab was conjugated with deferoxamine and radiolabeled with (89)Zr.

272 tuzumab was conjugated with deferoxamine and radiolabeled with (89)Zr.

273 MSB0010853 was radiolabeled with (89)Zr.

274 Results:(64)Cu-DOTA-alendronate was radiolabeled with a 98% yield.

275 All 3 tracer candidates were radiolabeled with a PET nuclide and tested in vivo in ta

276 , RO6931643, and RO6924963 were successfully radiolabeled with a PET nuclide at high specific activit

277 bladder with fluorescent-tagged tilmanocept, radiolabeled with both (68)Ga and (99m)Tc.

278 ine-related M4 PAMs that can be conveniently radiolabeled with carbon-11 as PET tracers for the in vi

279 Lead compound MT107 (7f) was radiolabeled with carbon-11.

280 In this work, two galectin-3 inhibitors were radiolabeled with fluorine-18 and used as surrogate PET

281 Radiolabeled with iodine-125, Rho-FF-Van shows strong ra

282 Lysine-ureido-glutamate inhibitors of PSMA radiolabeled with positron-emitting radionuclides can be

283 ole of the immune cells, BiTE molecules were radiolabeled with the PET isotope (89)Zr and studied in

284 ddition to its inherent cytotoxicity, can be radiolabeled with tracers for imaging and with beta- and

285 sessment of cortical uptake, bevacizumab was radiolabeled with zirconium-89 and infused intraarterial

286 lator p-SCN-Bn-DFO was conjugated to AMG102, radiolabeling with (89)Zr was performed in high radioche

287 r chelation with desferrioxamine B (DFO) and radiolabeling with (89)Zr, has become attractive.

288 DFO-p-benzyl-isothiocyanate (DFO-Bz-NCS) for radiolabeling with (89)Zr.

289 ted to the HER2 mAb trastuzumab, followed by radiolabeling with (89)Zr.

290 Their radiolabeling with (99m)Tc was shown to be efficient and

291 After radiolabeling with (99m)Tc, we performed in vivo SPECT i

292 Radiolabeling with long-lived positron emission tomograp

293 minepentaacetic dianhydride (DTPA), allowing radiolabeling with the Auger electron-emitting radionucl

294 pembrolizumab in vivo, accomplished through radiolabeling with the positron emitter (89)Zr.

295 onuclide pairs have now become available for radiolabeling with the potential for use as theranostic

296 his peptide, it was conjugated with NOTA and radiolabelled with copper-64.

297 (HEGF), coupled to a chelator for subsequent radiolabelling with (111)Indium ([(111)In]In(3+)), in a

298 e compounds were labeled with (64)Cu, with a radiolabeling yield of more than 99%.

299 ty of NH(2)OH.HCl used appears to affect the radiolabeling yield of phenethyl-closo-decaborate(2-) (B

300 action at room temperature to obtain optimal radiolabeling yields, and product purification using a P