ライフサイエンスコーパス: radiolabeling

1 enetriaminepentaacetic acid to allow (111)In radiolabeling.

2 ng site-specific conjugation of chelates for radiolabeling.

3 TE, which was stored in 50-nmol aliquots for radiolabeling.

4 te/HCl (pH 4.5) solution suitable for direct radiolabeling.

5 acyclononane-1,4,7-triacetic acid for (64)Cu radiolabeling.

6 ]sulfonyl fluorides as synthons for indirect radiolabeling.

7 n inverse stoichiometries used for efficient radiolabeling.

8 3) that served as an immediate precursor to radiolabeling.

9 rometry, tryptic peptide analysis, and (32)P radiolabeling.

10 abeled leukocytes was evaluated at 3 h after radiolabeling.

11 phatidylinositide (Ptide) metabolism without radiolabeling.

12 ble to rapidly study ADME/PK in vivo without radiolabeling.

13 he substrate variability caused by continual radiolabeling.

14 aceuticals and practical synthesis for (18)F-radiolabeling.

15 stability of the scFv's were analyzed after radiolabeling.

16 ting new chelators and prosthetic groups for radiolabeling.

17 simplified design for single-step kit-based radiolabeling.

18 hydrazino-nicotinamide (S-HYNIC) followed by radiolabeling.

19 ared to be due to the use of a procedure for radiolabeling (111)In-ibritumomab tiuxetan that differed

20 ial agents for mapping human SERT by PET and radiolabeling 37 with iodine-123, which could afford the

21 n types I and V, determined by (14)C-proline radiolabeling; (4) by pepsin digestion and analysis of c

22 modified with desferoxamine for zirconium-89 radiolabeling ((89)Zr-DNP) and a near-infrared fluorochr

23 Here we present two methods for radiolabeling adeno-associated virus (AAV), one of the m

24 r of T-cell activation that can be imaged by radiolabeling an anti-ICOS antibody and performing PET s

25 In vivo pulse radiolabeling analyses in retinal ganglion cell neurons

26 Radiolabeling analysis of cultured COS-7 cells overexpre

27 Using in vitro radiolabeling and a rapid quenched-flow apparatus, we ex

28 ion by the modified probe was assessed using radiolabeling and a standard chronocoulometry method; bo

29 We conclude that performing the radiolabeling and CAFE assays in parallel is currently t

30 rands that were independently detected using radiolabeling and chronocoulometry.

31 Metabolic radiolabeling and epifluorescence microscopy of Jurkat l

32 on and purification of recombinant proteins, radiolabeling and evaluation in vivo.

33 Here, we report our methodology for radiolabeling and imaging monodisperse pharmacologic aer

34 We have previously reported on the radiolabeling and in vitro binding properties of monoclo

35 After conjugation with DOTA for (64)Cu radiolabeling and IRDye 800CW as a fluorophore, dual-lab

36 Radiolabeling and isotope dilution studies now confirm t

37 atalysis, we conducted a series of catalytic radiolabeling and kinetic experiments on the C-terminal

38 of the macropa chelator enabled quantitative radiolabeling and may facilitate the clinical translatio

39 chondroitin sulfate determined by (35)SO(4) radiolabeling and measuring the sensitivity to endo-beta

40 Radiolabeling and microPET brain imaging studies were pe

41 affinity for integrin alphavbeta6, for (18)F radiolabeling and PET imaging of BxPC3 pancreatic adenoc

42 ors through conjugation with DOTA for (64)Cu radiolabeling and PET.

43 nd purification requires about 2-3 h and the radiolabeling and postlabeling purification requires abo

44 Methods: Simultaneous (89)Zr-radiolabeling and protein conjugation was performed in o

45 develop a simple, remote, "1-pot" method of radiolabeling and purification for the scaled-up radioio

46 The precursor for radiolabeling and reference compounds was synthesized in

47 onsidered to have non-obvious strategies for radiolabeling and require a more customized approach.

48 Using both radiolabeling and sensitive bioanalytical methods, we de

49 ously developed solution-phase (18)F-"click" radiolabeling and solid-phase radiolabeling using 4-[(18

50 g of one polymer construct was determined by radiolabeling and subcellular fractionation.

51 ated to maleimide-desferrioxamine for (89)Zr radiolabeling and subsequent small-animal PET/CT acquisi

52 Previous radiolabeling and two-dimensional (2-D) gel studies of t

53 and fluorescence, calcium imaging, phosphate radiolabeling, and a beta-arrestin-dependent luciferase

54 rescence, western blot analysis, pulse-chase radiolabeling, and biochemical subcellular fractionation

55 This study reports the synthesis, [(123)I]radiolabeling, and biological profile of a new series of

56 rapid amplification of cDNA ends (RACE), 5' radiolabeling, and exonuclease digestion, which revealed

57 atorial chemistry, site-specific solid-phase radiolabeling, and in vivo imaging for the rapid screeni

58 On the basis of site-directed mutagenesis, radiolabeling, and kinetics experiments carried out with

59 o-immunoprecipitation, [(32)P]orthophosphate radiolabeling, and measurement of lipolysis.

60 ards, different isotope labeling strategies, radiolabeling, and predicted ionization efficiencies are

61 , monitored wax biosynthesis through [(14)C]-radiolabeling, and sequenced the transcriptome.

62 njugation, providing a promising alternative radiolabeling approach that maintains the native in vivo

63 Our direct radiolabeling approach, allows for immediate screening o

64 Here we compare the three different radiolabeling approaches and report the effects on PET i

65 ver, we employed shRNA library screening and radiolabeling approaches, as well as in vitro and in viv

66 Here, we develop a radiolabeling assay and use stopped-flow kinetics to est

67 Protein radiolabeling assays showed that, although individual th

68 -N'-ethylcarbodiimide with subsequent (64)Cu radiolabeling at 37 degrees C for 30 min.

69 labeling with thin layer chromatography and radiolabeling by glycosylation.

70 After radiolabeling, cell viability was unchanged.

71 nt imaging properties but greatly simplified radiolabeling compared with other (68)Ga-PSMA conjugates

72 Optimization of [(18)F]radiolabeling conditions and subsequent stability analys

73 cted cells was manipulated immediately after radiolabeling de novo-synthesized bacterial proteins.

74 After radiolabeling, each peptide was administered intravenous

75 5 degrees C for 2h) of (52)Mn gave excellent radiolabeling efficiencies of 97-100% and 98-100% respec

76 Radiolabeling efficiencies ranged from 33% to 88%, and i

77 exhibited exceptional cell transfection and radiolabeling efficiencies, providing an overall advanta

78 The described novel protocol improves the radiolabeling efficiency and efficacy of DOTATOC, provid

79 The radiolabeling efficiency was 80%-85%, radiochemical puri

80 Two control radiolabelings, either with unreduced hMN-14 or with IMP

81 of the techniques, the different methods of radiolabeling erythrocytes, the procedure, useful indica

82 Finally, a preliminary radiolabeling essay has proven the facile [(18)F]-fluori

83 Metabolic radiolabeling experiments demonstrated that high level e

84 Radiolabeling experiments further demonstrated MltG-depe

85 On the contrary, radiolabeling experiments revealed impaired synthesis of

86 pared from a wzxE-null mutant, and metabolic radiolabeling experiments revealed the accumulation of l

87 (55)Fe-radiolabeling experiments with human cells depleted of C

88 a combination of kinetic studies, selective radiolabeling experiments, and cell viability assays to

89 Using radiolabeling experiments, we show that this carbide ori

90 Using co-immunoprecipitation and (55)Fe-radiolabeling experiments, we therefore studied the role

91 ected cells and biochemically by pulse-chase radiolabeling experiments.

92 c relationship was confirmed through various radiolabeling experiments.

93 experimentally confirmed by two independent radiolabeling experiments.

94 for quantitative metabolite profiling, i.e., radiolabeling followed by high-performance liquid chroma

95 this laboratory and elsewhere, the method of radiolabeling had an important effect on the biodistribu

96 nnocuous, appending nanoparticles with these radiolabeling handles can have dramatic effects on impor

97 Heat-induced radiolabeling (HIR) yielded (89) Zr-Feraheme (FH) nanopa

98 Radiolabeling identified sn-2 monoacylglycerol as an ini

99 The position of radiolabeling in the 3-N-methyl group was confirmed by [

100 ter conjugation to a DFO chelator and (89)Zr radiolabeling, in assays including cell uptake, internal

101 Radiolabeling, including purification, was performed in

102 he utility of the process in enabling (18) F-radiolabeling is also presented.

103 Efficient radiolabeling is directly performed with aqueous [(18)F]

104 Despite these rapid developments, (89)Zr radiolabeling is still performed manually.

105 by conjugating A9 with the DTPA chelator and radiolabeling it with (111)In.

106 Using pulse-chase radiolabeling, it was determined that the portal protein

107 tapa-trastuzumab conjugates displayed faster radiolabeling kinetics with more reproducible yields und

108 We report optimized protocols for radiolabeling liposomes with (52)Mn, through both remote

109 ations, including insensitivity, reliance on radiolabeling, low throughput and an inability to resolv

110 high specific activities (50-99 Ci/mmol) in radiolabeling, meeting the threshold required for radiol

111 here an improved MAG3 conjugation and 99mTc radiolabeling method capable of generating high radioche

112 We have characterized an efficient, 1-step radiolabeling method that produces stable, therapeutical

113 high yield, high specific activity, one-step radiolabeling method, high selectivity and favorable kin

114 We present a novel solid-phase based (45)Ti radiolabeling methodology and the implementation of (45)

115 The (18)F-radiolabeling methodology shown here is a robust procedu

116 r, there is a dearth of efficient and simple radiolabeling methods for aromatic C-H bonds, which limi

117 generated a range of innovative chelate-free radiolabeling methods that exploit intrinsic chemical fe

118 greement with published values determined by radiolabeling methods.

119 tween Hint1 and LysRS, a series of catalytic radiolabeling, mutagenesis, and kinetic experiments was

120 Similar yields were obtained in a subset of radiolabelings (n = 7) with >3.7 GBq of (131)I.

121 Classic methods for radiolabeling nanoparticles involve functionalization of

122 ry of 9 mechanistically distinct methods for radiolabeling nanoparticles is presented.

123 A central challenge in radiolabeling nanoparticles is to identify alternative c

124 Methods: Radiolabeling of (18)F-AlF-RESCA-IL2 and (68)Ga-Ga-NODAG

125 e, 1-step, room-temperature syringe-and-vial radiolabeling of (68)Ga radiopharmaceuticals.

126 Radiolabeling of 5-HT7R selective compounds was performe

127 n, and SDS gel analysis revealed 2-fold more radiolabeling of 55-58-kDa 2B15-His by PKCalpha than by

128 Radiolabeling of 7 with no carrier added (18)F-radioisot

129 nation at RT was successfully applied to the radiolabeling of [(18)F]-2-fluoroethylamines in which th

130 , leading to a regiospecific reaction in the radiolabeling of [(18)F]-fluorodeprenyl.

131 Radiolabeling of a DOTA-folate conjugate (cm09) was perf

132 ion-reconstruction approach to the carbon-14 radiolabeling of alkyl carboxylic acids is presented.

133 Radiolabeling of antibodies and antibody fragments facil

134 20.3 min) possesses the unique potential for radiolabeling of any biological, naturally occurring, or

135 Our method does not require radiolabeling of any components and therefore can be use

136 ortant and versatile building blocks for the radiolabeling of biomolecules via Huisgen cycloaddition

137 This paper describes the radiolabeling of biotin with the positron emission tomog

138 allele (as1 allele) results in the exclusive radiolabeling of bona fide substrates of the mutant kina

139 The conjugation and radiolabeling of bovine serum albumin is used as an exam

140 (111)In radiolabeling of DOTA and (64)Cu radiolabeling of CB-TE2A conjugates yielded 370-1,850 an

141 eous sodium chloride (NaCl)-based method for radiolabeling of chelator-modified peptides for molecula

142 The radiolabeling of cm09 was achieved in a greater than 96%

143 Radiolabeling of cm09 was achieved with a radiochemical

144 otein kinases and [gamma-32P]ATP resulted in radiolabeling of CPT-I only by CKII.

145 (111)In radiolabeling of DOTA and (64)Cu radiolabeling of CB-TE2

146 ctivity (22 +/- 4 Mbq/nmol) suitable for the radiolabeling of DOTA-conjugated vectors.

147 n method of (44)Sc at a quality suitable for radiolabeling of DOTA-functionalized biomolecules.

148 ification of the ischemic state via targeted radiolabeling of hypoxia-induced angiogenic receptors is

149 Radiolabeling of IL2 with a positron-emitting isotope co

150 Radiolabeling of intact Sf9 cells expressing iPLA2beta w

151 Radiolabeling of monoclonal antibodies (mAbs) with an in

152 evaluates the use of (89)Zr-chloride in the radiolabeling of monoclonal antibodies conjugated with d

153 Radiolabeling of MSB0010853 with (89)Zr was performed wi

154 ibroblasts from a human patient, pulse-chase radiolabeling of newly synthesized proteins is used to d

155 Radiolabeling of NOTA-AE105 with (64)Cu and (68)Ga was s

156 de as verified by both mass spectroscopy and radiolabeling of OPBM.

157 eloped in this study will also be useful for radiolabeling of other thiolated biomolecules.

158 Selective in vivo radiolabeling of plasma NTBI with (59)Fe revealed simila

159 Direct radiolabeling of proteins can result in the loss of targ

160 s the first that enables site-specific (11)C-radiolabeling of proteins.

161 By in vivo radiolabeling of rat DRGs, coupled to mass spectrometry

162 Radiolabeling of recombinant human cPLA(2)gamma with [(3

163 Radiolabeling of RS7-DOTA conjugate with (177)Lu-acetate

164 development of these modalities through the radiolabeling of somatostatin analogs with various radio

165 In addition, [(3)H]inositol radiolabeling of sterol biosynthesis inhibitor-treated w

166 Photoaffinity labeling studies show radiolabeling of subunits c and e.

167 [(18)F]Radiolabeling of sulfonyl chlorides in the presence of c

168 The TF-targeted tracer was developed through radiolabeling of the anti-human TF monoclonal antibody (

169 Radiolabeling of the DOTA-rhenium-cyclized peptides with

170 difficult using conventional methods such as radiolabeling of the oligonucleotide or fluorescence con

171 Radiolabeling of the prostate-specific membrane antigen

172 hy (PET) that is being increasingly used for radiolabeling of tumor-targeting peptides.

173 Radiolabeling of VUF11211 gave [(3)H]VUF11211, which in

174 parameters has historically required direct radiolabeling or competition with a labeled tracer.

175 ncountered with previous strategies based on radiolabeling or fluorescence timer proteins, allowed us

176 Using pulse-chase radiolabeling, peptide-N-glycosidase F treatment, lectin

177 Radiolabelings performed with freshly prepared solutions

178 recurrent prostate cancer by the use of one radiolabeling precursor, which can be radiolabeled eithe

179 c strategy that affords modular synthesis of radiolabeling precursors via a copper-catalyzed 'click'

180 was employed in efficiently synthesizing the radiolabeling precursors.

181 The high specific activity one-step radiolabeling preparation and high selectivity of [(123)

182 Step 1A of this protocol describes a (64)Cu-radiolabeling procedure for 1,4,8,11-tetraazacyclododeca

183 Step 1B of this protocol describes the radiolabeling procedure for 4,11-bis(carboxymethyl)-1,4,

184 The radiolabeling procedure gave > or =95% radiometal incorp

185 the products, and the lack of cost-effective radiolabeling procedures.

186 h impactor stage for all 3 aerosols, and the radiolabeling process itself did not affect their partic

187 ed autophagic flux by two different methods (radiolabeling proteins and a dual-colored LC3 plasmid);

188 gradation rates were determined using (35) S radiolabeling pulse chase.

189 Radiolabeling pulse/chase analysis demonstrated that E2F

190 DC018) equipped with both a DOTA chelate for radiolabeling purposes and a fluorophore (IRdye800CW) to

191 cal metal ion chelators that can be used for radiolabeling reactions have residualizing properties in

192 ers, but irrespective of the particle class, radiolabeling remains a key step.

193 Radiolabeling required 35 +/- 5 (mean +/- SD) min starti

194 charged nucleic acids (siRNA) and to undergo radiolabeling, respectively, for potential theranostic a

195 Pulse-chase radiolabeling reveals that a ypk1Delta mutant exhibits i

196 trated by its use in an industrial carbon-14 radiolabeling setting.

197 ire process of conjugation, purification and radiolabeling should take approximately 12.5 h.

198 (35)S-radiolabeling showed that MotA and MotB are present in a

199 The new methodology does not require radiolabeling, so it remarkably widens the range of poss

200 Methods: Radiolabeling, stability, cell uptake, and internalizati

201 of this study was to assess different (18)F radiolabeling strategies of the HER2-specific Affibody m

202 for the coupling of maleimide linkers, and 3 radiolabeling strategies were assessed: silicon-fluoride

203 Three radiolabeling strategies were evaluated to synthesize th

204 radiolabel molecules, and select a preferred radiolabeling strategy to progress for automated manufac

205 [(3)H]Dihydrosphingosine radiolabeling studies demonstrated that erg26-1 cells ha

206 [(3)H]inositol and [(3)H]dihydrosphingosine radiolabeling studies demonstrated that mutant cells had

207 Neutral lipid radiolabeling studies indicated that the rate of biosynt

208 Radiolabeling studies reveal that N(omega)-methoxy-L-arg

209 Phospholipid radiolabeling studies showed defects in the rate of bios

210 Phospholipid radiolabeling studies showed that arv1Delta cells harbor

211 Neutral lipid radiolabeling studies showed that erg26-1 cells also har

212 Radiolabeling studies showed that macropa, at submicromo

213 Using [(3)H]inositol radiolabeling studies, we found that the biosynthetic ra

214 a1p, the yeast G alpha subunit, in metabolic radiolabeling studies.

215 ncluding the precursor preparation and (18)F radiolabeling, takes 7-10 d.

216 synthetic biology approaches, biochemistry, radiolabeling techniques, and NMR and MS analyses, we ex

217 Using pulse-chase radiolabeling techniques, we find that newly synthesized

218 the help of sophisticated bioconjugation or radiolabeling techniques.

219 nts without using expensive spectroscopic or radiolabeling techniques.

220 We showed by dynamic protein radiolabeling that LLO synthesis was growth phase-depend

221 B0010853 biodistribution and tumor uptake by radiolabeling the Nanobody construct with (89)Zr.

222 After radiolabeling, the phage was tested for binding at 1, 5,

223 ared with their stored test PAS platelets by radiolabeling their stored and control platelets with ei

224 Development of a method for radiolabeling these PC analogues, via hydrogenation of a

225 In addition, after radiolabeling, this monoclonal identified the site of en

226 Using either mass spectrometry or radiolabeling, this reagent may be used to reveal sites

227 Currently, radiolabeling through macrocyclic chelators is the most

228 ction, which significantly increases overall radiolabeling time and causes radioactivity loss.

229 ermine proteoglycan degradation, zymography, radiolabeling to determine chondrocyte biosynthesis, and

230 Radiolabeling to produce (18)F-SO3F(-) was simple and af

231 Fluorine-18 radiolabeling typically includes several conserved steps

232 (18)F-"click" radiolabeling and solid-phase radiolabeling using 4-[(18)F]fluorobenzoic and 2-[(18)F]

233 Both in vivo radiolabeling (using [(32)P]orthophosphate) followed by

234 e prosthetic group), and rapid and efficient radiolabeling via click chemistry with (18)F-labeled tra

235 nsity in whole blood and after isolation and radiolabeling was 25.98 +/- 7.59 and 51.82 +/- 17.44, re

236 ld-type (wt) RFC was labeled; for K411A RFC, radiolabeling was abolished.

237 Radiolabeling was accomplished by a nucleophilic substit

238 Results: Radiolabeling was accomplished successfully with an inco

239 Radiolabeling was accomplished with high radiochemical y

240 Radiolabeling was achieved by methylation of ethyl 6-bro

241 Radiolabeling was achieved via standard electrophilic io

242 Radiolabeling was complete (>95%) within 5 min at room t

243 ) as a suitable radioligand lead, which upon radiolabeling was found to exhibit a high level of MAGL

244 In U937 cell membranes, the 47 kDa radiolabeling was inhibited in a concentration-dependent

245 ectrospray ionization-mass spectrometry, and radiolabeling was monitored by instant thin-layer chroma

246 Radiolabeling was not detected in membranes from HEK293T

247 In contrast, radiolabeling was not inhibited by 8,9-dihydroxyeicosatr

248 Radiolabeling was performed by pumping (89)Zr-oxalate an

249 (18)F radiolabeling was performed by reacting the tosylate pre

250 Radiolabeling was quantitative (>97%) after 5 min of inc

251 To study PIP(2) levels of cells without radiolabeling, we have developed a new method to quantif

252 Using fluorescence labeling and radiolabeling, we show that cholesterol modification ena

253 Enantiopure tosylate precursors for radiolabeling were obtained using chiral preparative hig

254 s exhibited DNA fragmentation in response to radiolabeling whereas only the p53(+/+) cells exhibited

255 nt in the solution phase, and its subsequent radiolabeling with (111)In (T(1/2) = 2.8 d) and (86)Y (T

256 -007 was successfully conjugated to DTPA for radiolabeling with (111)In at room temperature.

257 etriaminepentaacetic acid for the purpose of radiolabeling with (111)In.

258 ic acid (DOTA) conjugate of RS7 was used for radiolabeling with (177)Lu-acetate or (88/90)Y-acetate.

259 Radiolabeling with (18)F was based on the complexation o

260 rolled conjugation and polymerization before radiolabeling with (64)Cu for PET imaging in an apolipop

261 Radiolabeling with (64)Cu resulted in >95% of the (64)Cu

262 e-1,4,7-triacetic acid at the N terminus for radiolabeling with (64)Cu with a polyethylene glycol spa

263 C-terminal amino acids of bombesin(7-14) for radiolabeling with (64)Cu.

264 lator p-SCN-Bn-DFO was conjugated to AMG102, radiolabeling with (89)Zr was performed in high radioche

265 r chelation with desferrioxamine B (DFO) and radiolabeling with (89)Zr, has become attractive.

266 DFO-p-benzyl-isothiocyanate (DFO-Bz-NCS) for radiolabeling with (89)Zr.

267 ted to the HER2 mAb trastuzumab, followed by radiolabeling with (89)Zr.

268 Their radiolabeling with (99m)Tc was shown to be efficient and

269 After radiolabeling with (99m)Tc, we performed in vivo SPECT i

270 onjugated to bifunctional chelator HYNIC for radiolabeling with (99m)Tc.

271 de-mercaptoacetyltriglycine (MAG3) to permit radiolabeling with (99m)Tc.

272 d contains a tyrosine residue, which enables radiolabeling with 125I.

273 ane (CB-TE2A) was conjugated to c(RGDyK) for radiolabeling with 64Cu (t(1/2), 12.7 h; beta+, 17.4%; E

274 Further optimization entailed radiolabeling with 99mTc and biodistribution in an AR42J

275 nctionalized biomolecules for the purpose of radiolabeling with 99mTc for gamma detection or single p

276 dnones was further highlighted by successful radiolabeling with [(18) F]Selectfluor.

277 t protein liquid chromatography (FPLC) after radiolabeling with [(3)H]-free cholesterol (FC).

278 e human Kv1.1 protein in Sf9 cells, covalent radiolabeling with [(3)H]palmitate, chemical stability s

279 on of selective Triton X-114 solubilization, radiolabeling with [(3)H]palmitic acid, and sucrose dens

280 n elegant new technique for combining iodine radiolabeling with an azamacrocyclic chelator to confer

281 Radiolabeling with fluorine-18 ((18)F) facilitated produ

282 Radiolabeling with high specific activity [(11)C]methyl

283 Radiolabeling with I-124 was completed using a modified

284 ist 17 (DPC11870-11) is a DTPA conjugate for radiolabeling with In-111.

285 Radiolabeling with long-lived positron emission tomograp

286 After radiolabeling with positron-emitting carbon-11, [(11)C]C

287 Radiolabeling with technetium-99m in aqueous media was e

288 This series includes hydrophilic ligands for radiolabeling with the [(99m)Tc(CO)3](+) core (L8-L10),

289 minepentaacetic dianhydride (DTPA), allowing radiolabeling with the Auger electron-emitting radionucl

290 ugated to desferrioxamine (DFO) was used for radiolabeling with the PET isotopes 68Ga and 89Zr.

291 pembrolizumab in vivo, accomplished through radiolabeling with the positron emitter (89)Zr.

292 ange reaction, a method that is adaptable to radiolabeling with the positron-emitting isotope fluorin

293 onuclide pairs have now become available for radiolabeling with the potential for use as theranostic

294 cursors and methods are readily adaptable to radiolabeling with various radiohalides suitable for SPE

295 In 18 radiolabelings with (131)I in the range of 2.04-4.81 GBq

296 -methoxyphenyl)iodonium salt and its [(18)F] radiolabeling within a one-step, fully automated and cGM

297 e compounds were labeled with (64)Cu, with a radiolabeling yield of more than 99%.

298 ty of NH(2)OH.HCl used appears to affect the radiolabeling yield of phenethyl-closo-decaborate(2-) (B

299 F(121) was achieved in 90 +/- 10 min and the radiolabeling yield was 87.4% +/- 3.2%.

300 action at room temperature to obtain optimal radiolabeling yields, and product purification using a P