ライフサイエンスコーパス: raise

1 We have raised 94 antibodies against key Arabidopsis root protei

2 Our mutation rate estimates for baboons raise a further puzzle, suggesting a divergence time bet

3 y that children receive drug treatments that raise a red flag when viewed through the lens of treatme

4 domide and bortezomib frontline exposure has raised a growing need for novel treatments for patients

5 caffold of single-domain antibodies, here we raised a panel of MMP10-selective antibodies through imm

6 In the 1990s, reports from northern Thailand raised a troubling observation; some scrub typhus patien

7 ecessary inclusion of lead, a toxic element, raises a critical concern for future commercial developm

8 wever, brain activity is inherently dynamic, raising a challenge for maintaining stable mental states

9 However, concerns have been raised about possible destructive effects on cells due t

10 Concerns have been raised about the potential harmful effect of any preoper

11 Reanalysis of the authors' data raises additional concerns about their conclusions.

12 utilizes a mixture of polyclonal antibodies raised against recombinant nucleoproteins of representat

13 large panel of monoclonal antibodies (MAbs) raised against the L1 proteins of lineage A antigens.

14 e most effectively labeled with an antiserum raised against tyrosine hydroxylase (TH), the rate-limit

15 Restoring lipoprotein function with ApoA-I raising agents or blocking relevant scavenger receptors

16 This raises an important question: as past research shows tha

17 sed to variable circular or targetoid, often raised, and centrally ulcerated lesions covering up to 7

18 imals eventually reject tumors and cannot be raised at 37 degrees C.

19 hrough a 14.0% increase in the likelihood of raising at least one offspring to independence.

20 Our findings are of importance to raise awareness of this complication among clinicians tr

21 med-of-low-importance process of padding and raises awareness of the need to refine it for better per

22 y current pro-diversity initiatives focus on raising awareness about the fact that implicit bias and

23 ummit attendees identified the importance of raising awareness among critical care clinicians and key

24 ndancy of the recipient's pre-FMT microbiota raises barriers to donor microbiota engraftment.

25 red to intensive care unit (ICU) patients to raise blood pressure.

26 ients (ICCs) of five major CVD risk factors (raised blood glucose, raised blood pressure, smoking, ov

27 ajor CVD risk factors (raised blood glucose, raised blood pressure, smoking, overweight, and obesity)

28 Moreover, the number of category sets was raised by an order of magnitude.

29 Suggitt et al. reply to the concerns raised by Le Roux et al. on their original manuscript.

30 An attractive hypothesis raised by our data is that increased DNA methylation may

31 inally, we highlight issues and perspectives raised by the discovery of the first pharmaceutical stro

32 We discuss the unique biophysical questions raised by the presence of large extracellular ligand-bin

33 However, the issues raised by the toxic lead element and marginal stability

34 cussions of some of the key points that were raised by the workshop.

35 Because raising cAMP enhances 26S proteasome activity and the de

36 Raising cGMP, like raising cAMP, stimulated the degradation of short-lived

37 5 cm H2O (i.e., 4 mm Hg) during passive leg raising can predict preload unresponsiveness diagnosed b

38 These results raise caution against the over-generalisation of global

39 roteins, we investigated whether agents that raise cGMP may also regulate protein degradation.

40 In cells and cell extracts, raising cGMP also enhanced within minutes ubiquitin conj

41 We also tested if raising cGMP, like cAMP, can promote the degradation of

42 Raising cGMP, like raising cAMP, stimulated the degradat

43 Our findings raise concern about differential reproductive success am

44 These data raise concern that nontarget organisms may be exposed to

45 lates missing one of the typing loci, adh-1, raises concern about its suitability for continued use.

46 This raises concern for human exposure, especially should the

47 o in cultivated carrot growing in the UK and raises concern for the carrot and potato growing industr

48 y for choosing the rank hyperparameters also raises concern on derived results.

49 g healthcare workers than general population raising concern that healthcare workers could act as sil

50 high levels of acute-phase reactants should raise concerns about amyloid recurrence in allograft.

51 Our results raise concerns about the formation of toxic ring-cleavag

52 Augenlicht and colleagues raise concerns about the impact of diet on stem cell reg

53 These results raise concerns about the use of live-attenuated HSV-2 va

54 potential negative effects of hybridization raise concerns on the genetic integrity of endangered sp

55 More generally, such findings raise concerns regarding society's mental (ill)health an

56 Study findings raise concerns regarding the operational failure of stan

57 orbidities in patients with ESKD on dialysis raise concerns that they may have an elevated risk of se

58 Some studies have raised concerns about a potential association between th

59 ts 2008 emergence in pigs in the Philippines raised concerns about food safety, pathogenicity, and zo

60 Experimental and observational studies have raised concerns that giving intravenous (IV) iron to pat

61 This difference raises concerns about most past studies of approximate n

62 e iron supplementation during pregnancy also raises concerns about the potential adverse effects of i

63 per- and polyfluoroalkyl substances (PFASs) raises concerns among regulators tasked with protecting

64 ing recruited to work in the UK, this review raises concerns based on the need to effectively support

65 sually contain nicotine, which is addictive, raising concerns about e-cigarette use and nicotine addi

66 spite lower volumes of insecticides applied, raising concerns about insect conservation and highlight

67 ths and years following GBCA administration, raising concerns about long term toxicity.

68 working women's poor sleep health over time, raising concerns about sleep health disparities emanatin

69 ercial transgenic traits have been reported, raising concerns over their continued efficacy in WCR ma

70 es confirm previously reported drivers(6,7), raise doubts about others and identify novel candidates,

71 The purpose of this Perspective is to raise doubts about whether the FFA levels found in real-

72 y hours before bleaching was first detected, raising doubts about their possible roles in this proces

73 authors decide how to respond to the issues raised during peer review.

74 Warming-raised emission of soil GHG increases with the intensity

75 th single-organ transplant recipients, which raise ethical questions regarding equity and utility.

76 autonomic signaling pathways responsible for raising exercise heart rate are impaired in HFpEF is unk

77 s of engineered nanomaterial (ENM) have been raised, experimentally assessing toxicity of various ENM

78 duced factor VIII activity with AIS/CES/LAS; raised factor VIII antigen with AIS/CES; and increased f

79 The cellular size raised from 0.4 x 1.0 to 0.9 x 1.6 mum on average, induc

80 folds, respectively, when the temperature is raised from 25 to 70 degrees C, while the volumes of the

81 Farmed oysters are handled, raised from seed, and often grown using suspended grow-o

82 The data in this Matters Arising article raise fundamental questions about the recently proposed

83 may instead represent the cost of effort and raise fundamental questions regarding the interpretation

84 These striking results raise fundamental questions regarding tumor innervation,

85 have shown few of the desired health gains, raising fundamental questions about current approaches.

86 e that prudently selected flagships can both raise funds for conservation and help target where these

87 The age estimate also raises further questions about the mode of evolution of

88 he most common grade 3-4 adverse events were raised gamma-glutamyltransferase (13 [16%] of 80 patient

89 HDL-C raising genetic variants in the gene locus of the target

90 hanges and rhythmic insulin responses with a raised glucose threshold, a hallmark of functional matur

91 This has raised hopes for applications in data encryption, data s

92 low and middle-income countries (LMICs) have raised hopes that artificial intelligence (AI) might hel

93 for clinical successes with gene correction, raising hopes amongst patients and clinicians worldwide.

94 rom natural gas to electric heat pumps would raise household heating bills and increase damages from

95 he high intensity and brightness of SR beams raise important issues regarding the potential damage in

96 These findings raise important questions not only about the optimal ven

97 iversity impacts disease susceptibility, and raises important concepts about mechanisms that can be i

98 generates substantial remittance flows, but raises important concerns for migrant well-being.

99 ed failure in a range of clinical conditions raises important questions about the degree of objectivi

100 This raises important questions concerning population-genetic

101 nest success in response to light exposure, raising important questions about how responses to senso

102 ntal model, analysing 24 wild-born specimens raised in captivity from 6 months to 2 years old.

103 hite-footed mice (P. leucopus) were born and raised in captivity, and chronically exposed as adults t

104 uestion of enteral nutrition is increasingly raised in NIV users ALS patients.

105 major depression, compared with individuals raised in their home environment, those reared in adopti

106 the primary visual cortex (V1) of awake mice raised in three different conditions (standard-reared, d

107 scribe a pathway wherein sleep fragmentation raises inflammatory-related white blood cell counts (neu

108 r in lieu of sugar-sweetened beverages, have raised interest in water safety, access, and consumption

109 h those two quantities decayed; this finding raises interesting questions about the evolutionary natu

110 current density ~10% of sensory neurons) and raised intracellular Ca(2+) levels in arterial smooth mu

111 IIH is a condition of raised intracranial pressure of unknown cause, usually o

112 the thylakoid's mesoscale vertical structure raises intriguing possibilities for regulation of photos

113 a patient with PCG may be at risk of sudden raised IOP resulting in acute hydrops, and early treatme

114 ent of pleiotropy exhibited by SLC39A8 A391T raises key questions regarding how a single coding varia

115 to the conspicuous signatures of archetypal raised-leg postures in the accelerometer data.

116 large proportion of endurance athletes have raised levels of cardiac biomarkers (troponins and B-typ

117 the potentiation profile on CFTR structures raises mechanistic hypotheses on drug action, suggesting

118 cids are found in the guts of conventionally raised mice compared with germ-free animals.

119 his study in a preterm-birth-enriched cohort raises more questions than it could answer and underscor

120 Aminocyclopropenium ions have raised much attention as organocatalysts and redox activ

121 patterns of intergenerational plasticity and raise new questions about the interface between intergen

122 ive inheritance of environmental effects and raise new questions about the proximate and ultimate cau

123 to understand the basis of mHTT toxicity and raises new therapeutic opportunities.

124 potentially serious confound in prior work, raising new theoretical and methodological challenges fo

125 nia losses in line with temperate losses and raising nitric oxide losses above them.

126 Long-standing radical species have raised noteworthy concerns in organic functional chemist

127 cose intolerance and insulin resistance when raised on a high-fat diet, compared to wild-type (WT) mi

128 Recent developments in nanotechnology raise opportunities for the application of nano targeted

129 encing are becoming financially feasible but raise or exacerbate complex issues such as variants of u

130 omoter region showed that the two adipokines raised PCSK9 promoter activity via the involvement of a

131 mechanisms: by complexing Fe(2+) and thereby raising pe, and by making hematite more negatively charg

132 Likewise, raising pH or apical perfusion did not improve clearance

133 re tolerant of ongoing OA, whereas a captive-raised population sourced from a region of weaker upwell

134 Although these data raise potential concerns for public health, convincing e

135 Effort to raise public awareness screening for lung cancer has bee

136 aining the next generation of scientists and raising public awareness for science.

137 These findings raise questions about documentation accuracy and utility

138 age of recruits (median age <60 years), and raise questions about generalisability to routine clinic

139 tion of a limited number of European species raise questions about how macro- and microevolutionary p

140 omic activation not observed during GPi DBS, raise questions about its role as the primary mechanism

141 fferences in A. cahirinus sleep architecture raise questions about the evolutionary drivers of sleep

142 Our findings raise questions about the nature of the waterbodies that

143 ealthcare are normal, unwarranted variations raise questions about the quality, appropriateness, and

144 fuge areas during intense glacial stages and raise questions concerning understudied migration pathwa

145 ecent insights into peripheral clock biology raise questions of clock emergence, its concordance with

146 nous chitin production has been detected and raise questions regarding chitin's potential function in

147 These observations raise questions regarding the biological role of tooth-i

148 ever, subsequent observations of Fomalhaut b raised questions about its status: Unlike other exoplane

149 The commentaries raised questions about normativity, human rationality, c

150 tencies between indices of SPG-strength have raised questions about the active role SPG-strength and

151 The Flint water crisis raised questions about the factors resulting in unaccept

152 This has raised questions regarding potential strain-specific dif

153 st, yet their typical short-range nature has raised questions regarding the role of disorder.

154 This observation raises questions about how tetraploid cells evolve and m

155 ons of pets, such as cats, ferrets and dogs, raises questions about the susceptibility of animals und

156 rly equipped to survive rapid changes, which raises questions about the vulnerability of contemporary

157 This raises questions about whether the same decision-making

158 mes exhibit vastly greater complexity, which raises questions not addressed by this bacterial paradig

159 ristic of trimethylamine methyltransferases, raising questions about the activities of these proteins

160 tive processing in the absence of awareness, raising questions about the conditions necessary for vis

161 her metal cations can substitute for Mg(2+), raising questions about the role different metals may pl

162 but its topological organization is unknown, raising questions about the subcellular localization of

163 have been primarily in First World nations, raising questions in some settings about the use of emer

164 RR 1.80, 95% CI 1.22-2.66) had significantly raised rates of ESLD, compared to those who were cured.

165 r trauma such as surgery, concerns have been raised regarding adverse effects from GC, thereby necess

166 In humans, ketamine has been demonstrated to raise resting BP, although it has not been studied with

167 olicies should be considered to address this raised risk as the pandemic response evolves.

168 Current technologies raise safety concerns for unintended gene propagation.

169 pregnancy (ICP), a disorder characterised by raised serum bile acids, are at increased risk of develo

170 This pattern of vast allelic polymorphism raises several questions-How do different signaling vari

171 ugh a majority of the recovered subjects had raised significant NAb titers, there is a substantial nu

172 Gilead et al. raise some fascinating issues about representational sub

173 These analyses indicate that HDL-C raising strategies could be considered for the preventio

174 Self-regulation interventions raised student engagement in the first few weeks but not

175 science interventions have shown promise in raising student persistence and completion rates in a ha

176 pproach to HCV vaccine development, but they raise substantial ethical and practical concerns.

177 y significant increased aggregate formation, raised superoxide levels (ROS), and altered mitochondria

178 ts human health and wellbeing and indirectly raises survival.

179 Elevated cholestatic enzymes on blood tests raise suspicion of these entities.

180 to 10% during the test (negative passive leg raising test).

181 However, concerns have been increasingly raised that relying on the potential of BECCS to achieve

182 A clinical score (RAISE) that used left ventricular remodeling (hypertroph

183 ch inhibits cellular adenosine uptake, could raise the extracellular adenosine concentration and damp

184 Specifically, we raise the following issues: (a) standardization can lead

185 Such a drug would raise the hope for a cure to many P2X7-dependent patholo

186 Our preliminary results raise the hypothesis that filler utterance would often o

187 These results raise the intriguing possibility of the rational enginee

188 nt reports of unexpected emissions of CFC-11 raise the need to better quantify releases from these ba

189 widespread expression in the nervous system, raise the possibility of a general role in temporal patt

190 logical relevance of OCLTT for Tigriopus and raise the possibility of microhabitat selection being us

191 o the participating molecular mechanisms and raise the possibility of SERPINB1 and IL-33 as potential

192 sregulated inflammation, such as sepsis, and raise the possibility that CB(1)R-signaling may constitu

193 These findings raise the possibility that hierarchical timescales repre

194 Our data raise the possibility that human CXCR5IFN-gammaCD8 T cel

195 -host interplay in CHIKV symptomatology, and raise the possibility that immune modulation is a therap

196 video that demonstrated nonsterile technique raise the possibility that infections following invasive

197 ated gene regulation via 5' UTR binding, and raise the possibility that noncoding mutations in the AT

198 These findings raise the possibility that the increased intracellular i

199 trinsic circadian timekeeping properties and raise the possibility that these contribute to daily reg

200 The findings raise the possibility that, if ubiquitination of H2A cou

201 The non-native protein functions also raise the prospect of future biocompatible devices where

202 These observations raise the question about whether enhancement of the circ

203 Previous reports raise the question if motor function is modulated by sub

204 s incidences of subtype transdifferentiation raise the question of to what extent the tumor character

205 These results raise the question of whether biodiversity-disease relat

206 These findings raise the question of whether social communication and i

207 r the identification of breast pCR after NST raise the question whether breast surgery is a redundant

208 Our data raise the striking possibility that only increments in s

209 nt Amazonian fires over the last decade have raised the alarm about the fate of the Earth's most biod

210 ersynthesized the LcrV antigen of Y. pestis, raised the amounts of LcrV enclosed in OMVs by the type

211 nflammatory drugs (NSAIDs) has progressively raised the attention toward the gastrointestinal, renal,

212 These findings have raised the conundrum of how to appropriately define and

213 Arcaute et al. raised the issue of whether specific cities with extreme

214 The identification of BSE in two goats raised the need to reliably identify BSE in small rumina

215 cy with a polymerisation domain substitution raised the organelle DNA polymerase error rate by 140-fo

216 This has raised the possibility of anticipating disease (re-)emer

217 he results of some small-cohort studies have raised the possibility of such a pleiotropic effect for

218 ny outer-membrane translocon homologs, which raised the question of the origin of E. gracilis's middl

219 with greater exposure to active iTBS, which raised the question of whether observed effects persiste

220 syndrome (SARS)-related coronaviruses (CoVs) raised the specter of potential future outbreaks of zoon

221 lternative branched amine coreactants, which raises the analytical strength of ECL well beyond that o

222 ) however, the doubled vacancy concentration raises the charge carrier density and suppresses bipolar

223 t recent of these studies, the CANTOS trial, raises the exciting possibility that, in the foreseeable

224 This poses a problem for the macrophage and raises the fundamental question of how the phagocytic ce

225 Our work raises the hypothesis that impaired mitochondrial calciu

226 This raises the possibility for novel, microbiome-related the

227 Asymptomatic long-term infection raises the possibility of IAV shedding from tonsils, whi

228 th GFR between 30 and 60 and better survival raises the possibility of indication bias.

229 c clock gene expression in other brain sites raises the possibility of local circadian control of neu

230 Our study raises the possibility of repurposing the antipsychotic

231 f mobilized colistin resistance (mcr) genes, raises the possibility of untreatable bacterial infectio

232 This observation raises the possibility that epigenetic modifiers that im

233 ntiated TC risk in women, although our study raises the possibility that high blood concentrations of

234 Our study raises the possibility that higher concentrations of dis

235 on gating state with distinct binding sites raises the possibility that inhibition by aryl sulfonami

236 oke-affected brain's neural circuitry, which raises the possibility that such repair might be achieva

237 This raises the question as to the translatome remodelers tha

238 eadth in solution at room temperature, which raises the question as to what the spectrum of a single

239 This raises the question of defining the specific host and ba

240 ve a size limit of 39 nanometres(4-7), which raises the question of how larger cytoplasmic molecules

241 This naturally raises the question of how to maximize health and longev

242 pronounced during interglacial periods, this raises the question of the significance of bird migratio

243 This raises the question of whether cooperation can emerge an

244 dden cardiac death in the general population raises the question of whether endurance exercise could

245 This raises the question of whether therapeutic strategies th

246 The global significance of such associations raises the question of whether unidentified associations

247 neurodegeneration in the cerebellum in SCA17 raises the question of why ubiquitously expressed polyQ

248 This raises the question whether the penetrance is indeed 100

249 th the extinction of terrestrial beavers and raises the question whether the two events had a common

250 cate trust differ between individuals, which raises the question whether these differences have a sta

251 This raises the question, which cells remove cell debris when

252 This raises the question: Does interdisciplinary research col

253 This raises the question: what are the translatome remodelers

254 of synthesized vector DNA libraries, thereby raising the discovery cost of novel vectors.

255 dominantly comprise diploid cardiomyocytes, raising the hypothesis that cardiomyocyte polyploidy pos

256 osis and increases IL-6/IL-1beta expression, raising the hypothesis that IL-6 pathway antagonism in C

257 d spatio-temporal distribution in the brain, raising the possibility for subtype-specific targeting b

258 e volume of melt entering the crust is high, raising the possibility of transitions to more silicic a

259 ures different from multipotent progenitors, raising the possibility that an intermediate progenitor

260 lpha-synuclein (alpha-syn), tau, and others, raising the possibility that autophagy upregulation may

261 mmonly affected in alcohol-dependent adults, raising the possibility that cerebellar structures affec

262 inner choroids below a threshold of 300 mum, raising the possibility that ChT could be predictive of

263 rapid cellular infiltration of brain tissue, raising the possibility that disease progression could p

264 -dependent domain of fibronectin expression, raising the possibility that durotaxis underlies cell mo

265 thout virological confirmation of infection, raising the possibility that immunity in children can pr

266 s highly prevalent and enriched in Africans, raising the possibility that it is under positive select

267 benone behaves as an NQO1-dependent prodrug, raising the possibility that lack of neuronal NQO1 activ

268 erentially regulated by mRNA decay pathways, raising the possibility that one distinction between the

269 1+ T-cell frequencies than healthy controls, raising the possibility that proinflammatory CD151+ T ce

270 correlates with the class switch efficiency, raising the possibility that the minimal requirement for

271 de the development of Alzheimer's pathology, raising the possibility that they may have a pathogenic

272 clathrin and other vesicle-related proteins, raising the possibility that TSPAN5 might play a role in

273 in part owing to reduced tau disaggregation, raising the possibility that VCP may represent a therape

274 er and Grzybowski for encouraging debate and raising the profile of this issue.

275 lter, a hallmark of all known K(+) channels, raising the question how selectivity is achieved.

276 PCP pathway and cell-cell adhesion complexes raising the question if ctenophore cells are polarized b

277 during the performance of behavioral tasks, raising the question of how recorded activity relates to

278 sion produces heterogeneous methylomes, thus raising the question of how the DNA methylome remains st

279 ess small peptide fragments from ssDNA ends, raising the question of how the ~90 kDa TOP1 protein is

280 a specific set of Esx, PE, and PPE proteins, raising the question of how these substrates are recogni

281 t directly related to the bulk Dirac points, raising the question of whether there exists a topologic

282 ep (SWS) and rapid eye movement sleep (REM), raising the question of why and how specialized sleep ev

283 inson's patients perform stepping movements, raising the question whether the STN is involved in the

284 nts with frequency content up to 300-400 Hz, raising the question whether vestibular pathways contrib

285 ate the ability to re-identify genomic data, raising the specter of discriminatory or oppressive use

286 Raising the stakes during relationship formation might i

287 nests' structural insulation properties, to raise their broods (larvae and/or pupae) in advantageous

288 individuals), while intermediate individuals raised their response times at higher temperatures for s

289 voltaic (OPV) efficiencies continue to rise, raising their prospects for solar energy conversion.

290 channel was improved by as much as 52-fold, raising this quantity to about 84% of the corresponding

291 erentiation, however practical strategies to raise tissue PGE2 during IPF have been limited.

292 , evidence that MNPs might promote infection raises uncertainty about whether MNPs give net health be

293 in immune function in their native habitats, raised under conditions mimicking the natural thermal re

294 In contrast, emixustat-treated larvae raised under extensive dark-adaptation displayed signifi

295 d mice with full-length Mcl1 (controls) were raised under normal or germ-free conditions.

296 The emergence of this new viral pathogen has raised unique diagnostic questions for which there have

297 tial strategy for improving fetal growth and raising uterine artery blood flow in pregnancy, which ma

298 umptions in their reanalysis, and the issues raised were in fact dealt with through the peer-review p

299 o test preload responsiveness by passive leg raising were prospectively included.

300 Se(4) liquid increases as the temperature is raised, which can be attributed to changes in the chemic

301 the genetic background of the fish they were raised with.