ライフサイエンスコーパス: raise question about

1 L exposure to CpG oligodeoxynucleotide (ODN) raised questions about a central role for TLR-9.

2 erious to cycling cells than ATR inhibition, raising questions about ATR and Chk1 functions in the ab

3 f As(II,III) for Fe in our synthetic samples raises questions about both the possible occurrence and

4 This raises questions about causality and possible carbonaceo

5 Raising questions about cell viability, especially for s

6 t oral anticoagulants (NOAC) trials, thereby raising questions about comparative safety and effective

7 effect across many different service systems raises questions about coordination of services and sect

8 , sanitation, and hygiene interventions have raised questions about current methods for assessing env

9 Our study raises questions about decision regret in patients who a

10 eplicate the results of the initial studies, raising questions about differences in the behaviors of

11 Increasing use of genetic testing raises questions about disclosing secondary findings, in

12 These findings raise questions about documentation accuracy and utility

13 moking appears limited to Hispanic children, raising questions about ethnic differences in tobacco-re

14 ed to investigate aspects of fungal biology, raising questions about evolution and specialization wit

15 volved multiple times in a range of animals, raising questions about factors that drive such extreme

16 Indeed, most lncRNAs are not conserved, raising questions about function.

17 age of recruits (median age <60 years), and raise questions about generalisability to routine clinic

18 Differences in incidence by sex and race raise questions about genetic and environmental influenc

19 The combinatorial interplay of these enzymes raises questions about genetic buffering of SCFs in huma

20 Taken together, these findings raise questions about how best National Institutes of He

21 se to stimuli and cellular signaling events, raise questions about how cardiolipin concentration affe

22 These data raise questions about how long allergen tolerance is mai

23 tion of a limited number of European species raise questions about how macro- and microevolutionary p

24 logical roles of hydroxymethylation serve to raise questions about how this epigenetic modification e

25 However, they raise questions about how to best address potential thre

26 n examining institutional discrimination; to raise questions about how to train underrepresented scie

27 te mesodermal derivatives to the bauplan has raised questions about how this apparent gain in potenti

28 This knowledge therefore raises questions about how asthma affects fertility path

29 s roles in both cancer and Golgi trafficking raises questions about how GOLPH3 and the Golgi contribu

30 This raises questions about how plants manage to translate st

31 The study raises questions about how policy-makers deal with the c

32 New research raises questions about how such domains are defined with

33 This observation raises questions about how tetraploid cells evolve and m

34 rils of chimerism, including cheating, which raises questions about how the victims survive in nature

35 lantation and pathological metastasis, which raises questions about how this process is controlled.

36 Kerberos may be much darker, raising questions about how a heterogeneous satellite sy

37 However, iRhom2(-/-) mice appear normal, raising questions about how ADAM17 is regulated in other

38 dividual motors are not robustly processive, raising questions about how dynein-associated cargoes ca

39 great genomic distances from their targets, raising questions about how enhancers communicate with s

40 biome and less prevalent in the healthy gut, raising questions about how fusobacteria localize to CRC

41 independently of host-specific interactions, raising questions about how mutualism shapes the realise

42 of the only known vertebrate sweet receptor, raising questions about how specialized nectar feeders s

43 ons required to do this are extremely brief, raising questions about how their auditory cortex encode

44 ntrol and spontaneous imaginative processes, raising questions about how these regions interact to su

45 These data raise questions about immune memory responses in an acut

46 to manipulate the viral genome of interest, raising questions about in vivo functions of RNAi suppre

47 ctivation between animals, and target sites, raise questions about its hypothesized role as the prima

48 results clarify the H. habilis hypodigm, but raise questions about its phylogenetic relationships.

49 omic activation not observed during GPi DBS, raise questions about its role as the primary mechanism

50 get recommendations in recent guidelines has raised questions about its role with respect to cardiova

51 ever, subsequent observations of Fomalhaut b raised questions about its status: Unlike other exoplane

52 use paraquat is di-cationic in plasma, which raises questions about its ability to cross the blood br

53 nt in humans that localizes to the membrane, raises questions about its function in neddylation.

54 of a unique TCR chain in marsupials, TCRmu, raises questions about its possible role in early develo

55 evance of miR-29b in aortic disease but also raises questions about its specific role.

56 DSM criteria for major depressive disorder, raising questions about its clinical significance.

57 y seen in arbovirus-infected mosquito cells, raising questions about its importance as an antiviral d

58 since been shown to be a common phenomenon, raising questions about its role in DNA damage induced b

59 ertainty, but are much larger than expected, raising questions about its sources.

60 vergence relative to the remaining variants, raising questions about its taxonomic status.

61 ty in families of people with schizophrenia, raising questions about its utility in genetic studies.

62 rogression and subsequent events is unclear, raising questions about its value for stratification of

63 in or function compared with sham treatment, raising questions about its value for these patients.

64 The apparent strength of the cohort trends raises questions about life-course inequalities in the s

65 ion, particularly in obese and older donors, raises questions about limitations of the renal adaptive

66 onstraints on water resources are appearing, raising questions about limits to water availability.

67 prisingly few pathways signal between cells, raising questions about mechanisms for tissue-specific r

68 separase lacks microtubule-binding activity, raising questions about mechanisms underlying this pheno

69 Hypoxia is a normal feature of GC, raising questions about molecular mechanisms governing t

70 lypeptide-like (APOBEC) cytidine deaminases, raising questions about molecular mechanisms that genera

71 This outbreak raises questions about mumps vaccine effectiveness and p

72 The commentaries raised questions about normativity, human rationality, c

73 therapy (NAC) for operable breast cancer has raised questions about optimal local therapy for the axi

74 Results raised questions about our current understanding of the

75 This raises questions about our fundamental understanding of

76 sation of animals and humans by ribotype 078 raises questions about possible zoonotic transmission, a

77 nce in different diseases and in health have raised questions about potential pathogenic mechanism me

78 Research on geologic carbon sequestration raises questions about potential impacts of subsurface m

79 ARs appear to be linked to innate responses, raising questions about regulatory mechanisms that might

80 ingle organism and from different organisms, raising questions about sequence-specific effects on RNA

81 This finding raises questions about signal processing within the reti

82 These findings raise questions about skills transfer from simulation tr

83 d HslV within these bacterial genomes, which raises questions about specialized protein degradation s

84 ldwide shortage of viral transport media and raised questions about specimen stability.

85 of molecules in Phase III for poor efficacy raise questions about target identification and validati

86 ogical response to influenza vaccination and raise questions about the added benefits of using a quad

87 Our results raise questions about the assumed social-information ben

88 hallenges for spacefaring civilizations, and raise questions about the assumption of a thermoregulato

89 nhanced prospects for natural gas production raise questions about the balance of impacts on air qual

90 They raise questions about the concept of restricted antigen

91 The results raise questions about the continued use of traditional l

92 EG signature between humans and macaques but raise questions about the current interpretation of beta

93 st degradation of organic carbon in soil and raise questions about the current prediction of terrestr

94 Their results raise questions about the developmental formation of thi

95 These findings raise questions about the effect of antifungal agents an

96 ntrolled trials, published in 2015 and 2016, raise questions about the effectiveness of pressure ther

97 These results raise questions about the effectiveness of punishment fo

98 fferences in A. cahirinus sleep architecture raise questions about the evolutionary drivers of sleep

99 The results of the present study raise questions about the focus of risk assessment schem

100 elayed rectifier (FDR) potassium current and raise questions about the function of this current.

101 These properties raise questions about the identity of the lysosomal bind

102 These findings raise questions about the implications of notifying pati

103 tat6 in airway epithelium induces murine AHR raise questions about the importance of direct IL-4R eff

104 cell wall pores in plant uptake of MNMs, and raise questions about the importance of plant species to

105 s linked to the consumption of fresh produce raise questions about the mechanisms by which human path

106 Our findings raise questions about the nature of the waterbodies that

107 These findings raise questions about the origins of differences among S

108 These findings raise questions about the potential role of Itk and Rlk

109 se rate of suicidal behaviours, our findings raise questions about the practicality of relying on sle

110 These results raise questions about the prevalence of HPV infection in

111 the biogenesis and regulation of miRNAs, and raise questions about the processes and molecular mechan

112 ealthcare are normal, unwarranted variations raise questions about the quality, appropriateness, and

113 with proximal dendrites of granule cells and raise questions about the recurrent excitation hypothesi

114 The results raise questions about the relative effectiveness of inte

115 ctural versatility of amyloid filaments, and raise questions about the relevance of in vitro assembly

116 virus (AIV) H9 infection in frugivorous bats raise questions about the role of bats in IAV epidemiolo

117 Our findings raise questions about the role of isolated 3' UTR sequen

118 Taken together, these data raise questions about the role of PKCepsilon in driving

119 Surprisingly, these results raise questions about the rules for renal filtration, gi

120 These observations raise questions about the sources of the B cells that re

121 e of the overall transplant waiting list and raise questions about the stewardship of scarce resource

122 , however, patterns of amino acid usage that raise questions about the strength (and possibly the uni

123 These findings raise questions about the types of learning environments

124 These findings raise questions about the use of critical care at the en

125 These findings raise questions about the usefulness of pretreatment PSR

126 These findings raise questions about the value of PET-CT scans in this

127 tencies between indices of SPG-strength have raised questions about the active role SPG-strength and

128 rus transmission, particularly in India, has raised questions about the degree of mucosal immunity in

129 lts of blinded versus open trial designs has raised questions about the effectiveness of water qualit

130 e spliceosome functions in 3' end processing raised questions about the evolutionary origin and conse

131 ps across the United States in 2016 and 2017 raised questions about the extent of mumps circulation a

132 inding, and crystallographic structures have raised questions about the extent to which generalizatio

133 The Flint water crisis raised questions about the factors resulting in unaccept

134 ber X (gammaH2AX), a DNA damage marker, have raised questions about the fidelity of BrdU to label S-p

135 tructural analyses of ARFs and Aux/IAAs have raised questions about the functional complexes driving

136 een the CSS progenitor strains in that study raised questions about the impact of genetic divergence:

137 A group of U.S. senators recently raised questions about the increasing use of for-profit

138 an M. genitalium-and these tiny genomes have raised questions about the limits of genome reduction an

139 This apparent contradiction has raised questions about the mathematical foundations of m

140 igh-level Ag-specific Ab responses, but also raised questions about the mechanisms responsible for su

141 i Migratory Bird Flyway in Wisconsin, U.S.A. raised questions about the natural history of these rare

142 ee as a vehicle for added fat and sugar have raised questions about the net impact of coffee on healt

143 h morphometric and metagenomic analyses have raised questions about the prevalence of nontailed, ssDN

144 to a third HRV species, Human rhinovirus C, raised questions about the prevalence of these picornavi

145 studies of water quality interventions have raised questions about the risk associated with fecally

146 e continuing loss of global biodiversity has raised questions about the risk that species extinctions

147 dexamethasone (RVD) in this population have raised questions about the role and timing of transplant

148 proteins within mRNA processing bodies have raised questions about the roles of the Ccr4-Not complex

149 region for bidirectional signaling with MCM raised questions about the roles of the switch I and II

150 e nuclear power complex in Fukushima, Japan, raised questions about the safe operation of nuclear pow

151 The unexpectedly broken ionic lock has raised questions about the true conformation(s) of the i

152 flammatory syndrome in children' (MIS-C) has raised questions about the unique effects of severe acut

153 In addition, recent clinical trials have raised questions about the use of WBRT.

154 epeat expansion in the A subgenome that also raises questions about the A-genome progenitor.

155 after sleep deprivation in bipolar disorder raises questions about the appropriateness of these meth

156 This raises questions about the appropriateness of using rati

157 tyle of the intestinal parasite Blastocystis raises questions about the biochemistry and function of

158 concentrations in many cell culture studies raises questions about the biological relevance of the o

159 short, mismatched ssDNAs into their genomes raises questions about the biological significance of th

160 This raises questions about the cardiovascular side effects a

161 n breastfeeding duration or exclusivity also raises questions about the causal nature of the observed

162 The identification of this new factor raises questions about the causal relationships between

163 This raises questions about the cellular capacity for adaptat

164 mall size of the treatment effects, however, raises questions about the clinical utility of this proc

165 loser examination of these studies, however, raises questions about the conclusion that poaching is d

166 vascular risk factors in both conditions and raises questions about the current separation of the two

167 This raises questions about the development of basic visual f

168 conserved proteins in multiple processes and raises questions about the endogenous substrate(s) and r

169 availability of so many approved treatments raises questions about the ethics and safety of placebo-

170 The work also raises questions about the evolutionary changes in this

171 t adopt at least five different folds, which raises questions about the evolutionary processes that m

172 thematics (STEM) settings is provocative and raises questions about the extent to which gender bias m

173 This differential impact raises questions about the feasibility of a carbon tax t

174 n plant immunity and the AM symbiosis, which raises questions about the functioning and the ancestral

175 pression was silenced rapidly by methylation raises questions about the future application of such te

176 This conclusion raises questions about the geographic origins (Old World

177 ng disrupted for a relatively common species raises questions about the impacts on less tolerant grou

178 all aromatic amino groups in metabolites and raises questions about the intermediacy of this species

179 ieved, and the modest efficacy that resulted raises questions about the level of effect that is achie

180 r the selection of both NKT and MAIT subsets raises questions about the mechanisms underlying acquisi

181 empirical evidence regarding empathy, which raises questions about the ordering and modulation of di

182 resulted from human overhunting, its demise raises questions about the Pleistocene overkill model, w

183 This raises questions about the possible off-target binding o

184 This study raises questions about the potential ability of thousand

185 Therefore, this result raises questions about the potential of epsilonretroviru

186 tion structure as putative species, our work raises questions about the practice of genome-based spec

187 lumn evolution in the earliest tetrapods and raises questions about the presumed vertebral architectu

188 This analysis raises questions about the relationship between methodol

189 nt interest in modeling biochemical networks raises questions about the relationship between often co

190 This difference raises questions about the relevance of TCR to neurologi

191 s been suggested as a mechanism, recent work raises questions about the role of biofilms in CF.

192 om endogenous lead; nevertheless, this study raises questions about the role of blood lead in CAD.

193 processing in the primate visual system and raises questions about the role of dorsal lateral genicu

194 This raises questions about the role of GR in maintaining the

195 t in shaping the evolution of phenotypes and raises questions about the role of morphological sensing

196 high prevalence of traditional risk factors raises questions about the role of NADPH oxidase in the

197 citation in the epileptic hippocampus, which raises questions about the role of sprouting and adult n

198 This observation raises questions about the role of systemic vs. local bl

199 This raises questions about the role of TNFR2 signaling in th

200 This study raises questions about the role, contribution and outcom

201 This raises questions about the safety of consumers, and it s

202 The cleavage of CoA raises questions about the side of the membrane where th

203 This finding raises questions about the sites for doped oxygen, the m

204 polarity and compartmentalization of neurons raises questions about the spatial and temporal regulati

205 wever, the discovery of histone demethylases raises questions about the stability of histone methylat

206 insects from discrete echo snapshots, which raises questions about the strategies they employ to tra

207 last, and glycosylation in the cytoplasm, it raises questions about the subcellular localization of g

208 ons of pets, such as cats, ferrets and dogs, raises questions about the susceptibility of animals und

209 E sequence were incorporated into the genome raises questions about the threat of ectopic recombinati

210 This raises questions about the typical anti-viral capability

211 ange between commercial and exhibition swine raises questions about the understudied interface betwee

212 This assumption raises questions about the validity and utility of curre

213 rly equipped to survive rapid changes, which raises questions about the vulnerability of contemporary

214 s and genes required to survive that stress, raising question about the role of stress-activated gene

215 ristic of trimethylamine methyltransferases, raising questions about the activities of these proteins

216 for tropical rainforest hunter-gatherers but raising questions about the antiquity of this behavior.

217 light chain LC7 recognition sequence on IC, raising questions about the apparently contradictory eff

218 nding on how the average ZT values are used, raising questions about the applicability of ZT in the c

219 rapies compared with chemotherapeutic drugs, raising questions about the assessment of changes in tum

220 on the rhythm by cADPR overexpression, thus raising questions about the conclusions of Dodd et al.

221 tive processing in the absence of awareness, raising questions about the conditions necessary for vis

222 y, they are evolutionarily distantly related raising questions about the conservation of the RNAi pat

223 in phenotype even within affected families, raising questions about the determinants of the progress

224 atric surgery for severe adolescent obesity, raising questions about the durability of early response

225 nt treatment failures in cases of skin rash, raising questions about the efficacy or suitability of t

226 only recombinant HCV to have spread widely, raising questions about the epidemiological background i

227 cross almost the entire Greenland ice sheet, raising questions about the frequency and spatial extent

228 allosum were generated after 7 weeks of age, raising questions about the function of the late-myelina

229 ates with lysosome subcellular localization, raising questions about the functional implications and

230 e revealed ordered internal water molecules, raising questions about the functional role of those wat

231 its a striking lack of curricular consensus, raising questions about the future of the cognitive scie

232 ates of stroke to approximately 1% per year, raising questions about the generalizability of these pr

233 acid is key in integrating these responses, raising questions about the impact of altering GA respon

234 nger effects on common carotid IMT in women, raising questions about the mechanism of the causal SNP

235 nctions in both developing and mature axons, raising questions about the mechanisms by which local tr

236 orer has been observed at several locations, raising questions about the nature, distribution and dyn

237 an small glomeruli from children and adults, raising questions about the origin of these podocytes.

238 use and confinement in livestock production, raising questions about the potential for occupational e

239 rae but has not been found in many bacteria, raising questions about the prevalence and function of c

240 pulations of naive T cells can be recognised raising questions about the processes that give rise to

241 cause of the emergence of a different clone, raising questions about the relevance of CMR in ET patie

242 rent depending on the modeling methods used, raising questions about the reliability of ensemble proj

243 ected variation among the ecological models, raising questions about the reliability of forecasts bas

244 ay reflect inhibition of FICZ metabolism and raising questions about the reported promiscuity of the

245 implements the formalism in a different way, raising questions about the reproducibility of such pred

246 her metal cations can substitute for Mg(2+), raising questions about the role different metals may pl

247 anisms, including some Vibrio genus members, raising questions about the role of microplastics as a n

248 e become available for treatment of myeloma, raising questions about the role of SCT for its manageme

249 ence of 2 viral lineages within West Africa, raising questions about the roles of reduced air traffic

250 genetic potential for heterotrophic growth, raising questions about the roles of SUP05 in the marine

251 shold in the acoustic brainstem response, so raising questions about the significance of PIEZO2 in th

252 tributes to localization of the MSL complex, raising questions about the source of the siRNAs involve

253 sfully passed a narrow gap frequently burst, raising questions about the sperm discharge mechanism in

254 show that climate change continues unabated, raising questions about the status of the "hiatus".

255 but its topological organization is unknown, raising questions about the subcellular localization of

256 to induce otic tissue in ectopic locations, raising questions about the sufficiency of Fgf and the d

257 ain small fractions of phenotypic variation, raising questions about the use of further studies.

258 th an ecotropic murine leukemia virus (MLV), raising questions about the validity of results obtained

259 ble effect on CKD or mortality months later, raising questions about the value of using small to mode

260 Montsechia is Barremian in age, raising questions about the very early divergence of the

261 ortcomings in data selection and methodology raise questions about their conclusions on trends and dr

262 quire different computational approaches and raise questions about their effectiveness on plant data.

263 ution, but competing phylogenetic hypotheses raise questions about their relationships, biogeography,

264 tic resonance spectroscopy data and analyses raise questions about their results.

265 Fe(7)O(9), and Fe(9)O(11) stoichiometry has raised questions about their existence within the Earth'

266 on drugs, recent federal investigations have raised questions about their potential to increase pharm

267 f neuron-specific endocytic protein isoforms raises questions about their importance for specialized

268 on of many HDAC isoforms in eukaryotic cells raises questions about their possible specificity or red

269 on structures of amelogenin protein in vitro raises questions about their role in enamel formation.

270 ms and have their own scoring systems, which raises questions about their similarity and the potentia

271 reveals NADPH-enriched populations of cells, raising questions about their distinct metabolic roles.

272 -specific Cre-recombinase transgenic models, raising questions about their general usefulness in rese

273 e, despite limited absorption and digestion, raising questions about their mechanism of action.

274 e too short for Dicer to excise their loops, raising questions about their mechanism of action.

275 emarkably broad-spectrum virocidal activity, raising questions about their modes of membrane associat

276 have been caused by GII.4 genotype strains, raising questions about their persistence in the populat

277 Our study raises questions about using snapshots of ES provision a

278 ordant in Parkinson disease clinical trials, raising questions about validity of these imaging measur

279 require thoughtful measurement decisions and raise questions about what a spatial effect represents.

280 for recombination hotspots in eukaryotes but raises questions about what forces have driven such rapi

281 pported by a theoretical model, our findings raise questions about whether the growth-mortality trade

282 ling by glutamate, but this distribution has raised questions about whether the protein actually cont

283 These findings raised questions about whether these vascular defects we

284 om, identified by gene ablation studies, has raised questions about whether they are directly mechani

285 a key feature of human motor learning, which raises questions about whether drugs increasing GABAergi

286 ever, the low bioavailability of resveratrol raises questions about whether the antidiabetic effects

287 This raises questions about whether the same decision-making

288 ociation with multiple filled prescriptions) raises questions about whether this association is causa

289 response to the mode of infant milk feeding, raising questions about whether formula feeding ought to

290 rted in up to 40% of the general population, raising questions about whether it is a distinct patholo

291 lation of several tyrosine kinase receptors, raising questions about whether oncogenic tyrosine kinas

292 pend on the spread of signals between cells, raising questions about whether PD are in different func

293 "Long-term study" of DC is raising questions about whether the procedure should be

294 otocols, but their phenotypes often overlap, raising questions about whether they are truly distinct.

295 n prostatic intraepithelial neoplasia (PIN), raising questions about whether TMPRSS2-ERG contributes

296 nd AURELIA, also showed improvements in PFS, raising questions about whether VEGF-inhibiting agents s

297 etic studies in this issue of Molecular Cell raise questions about which polymerases are copying the

298 ut some express up to five different toxins, raising questions about which toxins are necessary for t

299 D in infected captive cervid populations and raise questions about why some prion strains develop dru

300 ght have evolved sexual dimorphism, but also raise questions about why the putative ancestral-like MT