ライフサイエンスコーパス: raphe

1 (in the amygdala) and 5-HT1A binding (in the raphe).

2 bed subjectively: clustering at the temporal raphe.

3 n raphe, whereas 237 (11.2%) had BAV without raphe.

4 ific cell death of 5HT neurons in the dorsal raphe.

5 respiratory centres, including the medullary raphe.

6 nd midbrain vestibular nuclei, and medullary raphe.

7 wake-promoting function for the serotonergic raphe.

8 between MDD subjects and controls was in the raphe (132%, p=0.000).

9 d 110 [9.5%] at 5 years) vs patients without raphe (2 [1.8%] at 1 year, 3 [3.0%] at 2 years, and 5 [4

10 447 [24.4%] at 5 years) vs patients without raphe (30 [14.0%] at 1 year, 32 [15.0%] at 2 years, and

11 ficantly higher among patients with BAV with raphe (364 [19.9%] at 1 year, 393 [21.4%] at 2 years, an

12 airment in the electrical activity of dorsal raphe 5-HT neurons, attenuated hippocampal extracellular

13 ere we investigated the relationship between raphe 5-HT(1A) binding and brain-wide network dynamics o

14 related connectivity was not associated with raphe 5-HT(1A) binding.

15 stration, we found that inhibition of dorsal raphe 5-HT1A autoreceptors attenuates cocaine self-admin

16 ficantly higher among patients with BAV with raphe (77 [5.1%] at 1 year, 87 [6.2%] at 2 years, and 11

17 selective death of 5HT neurons in the dorsal raphe, a defined neuroanatomical pathway, and a behavior

18 We examined more rapid effects of raphe activation on two classes of principal neurons in

19 le mitral cells at rest were also excited by raphe activation, their odor responses were bidirectiona

20 th three discrete subregions in the superior raphe, an intermediate 5-HT-ir cell cluster, and an exte

21 To explore retino-raphe anatomical organization, retinal afferents labeled

22 Multivariable analysis identified calcified raphe and excess leaflet calcification (defined as more

23 Calcified raphe and excess leaflet calcification were associated w

24 ered with respect to the correlation between raphe and hippocampal 5-HT(1A) binding which was more pr

25 ciation between the presence and location of raphe and the risk of significant (moderate and severe)

26 ensity reduction (ADRVD) across the temporal raphe and various ocular parameters were analysed.

27 vosa associated genes in the adult and fetal raphe and ventral tegmental areas.

28 posterior hypothalamus, median raphe, dorsal raphe, and dorsal tegmentum.

29 bed nucleus of the stria terminalis, dorsal raphe, and lateral hypothalamus, which regulate primitiv

30 the number of raphe, calcification grade in raphe, and leaflet calcium volume were assessed with CT

31 to the RMTg, the median raphe, caudal dorsal raphe, and pontine central gray are major recipients of

32 nding to the supramammillary nucleus, median raphe, and the NI.

33 de evidence from zebrafish and mice that the raphe are critical for the initiation and maintenance of

34 de that dysfunction of even a portion of the raphe, as observed in many SIDS cases, can impair abilit

35 A5, rostral ventral medulla, A1, and midline raphe, as well as sympathetic preganglionic neurons in t

36 aled that specific optogenetic activation of raphe axons affected bulbar neurons through dual release

37 BAV morphology including the number of raphe, calcification grade in raphe, and leaflet calcium

38 ure of the raphe system, which consists of a raphe canal raised on a keel (wing), supported by rib li

39 how that in addition to the RMTg, the median raphe, caudal dorsal raphe, and pontine central gray are

40 imulation of serotonin neurons in the dorsal raphe causes mice to move more slowly without causing an

41 Tph2(+) versus Pet1(+),Tph2(low or negative) raphe cells.

42 long with some Pet1(+),Tph2(low or negative) raphe cells; in the other, approximately three-fourths o

43 Transient silencing of this rubro-raphe circuit in vivo via activation of the inhibitory D

44 Thus, dorsal raphe circuits switch between distinct operational modes

45 xpression and the consequent deficiencies in raphe-derived neuromodulators such as TRH.

46 Raphe-derived serotonin (5-HT) and thyrotropin-releasing

47 e lateral and posterior hypothalamus, median raphe, dorsal raphe, and dorsal tegmentum.

48 tween the two systems, we showed that dorsal raphe (DR) 5HT neurons selectively targeted the PBel.

49 ueductal gray (vlPAG) and neighboring dorsal raphe (DR) are integral to threat prediction, and are re

50 The locus coeruleus (LC) and dorsal raphe (DR) are monoamine nuclei implicated in stress-rel

51 Dorsal raphe (DR) harbors cell bodies of serotonin-producing ne

52 strates a role for the serotonin-rich dorsal raphe (DR) in anxiety following ethanol withdrawal.

53 The dorsal raphe (DR) is a heterogeneous nucleus containing dopamin

54 Serotonergic neurons in the dorsal raphe (DR) nucleus are associated with several psychiatr

55 of neuronal populations including the dorsal raphe (DR) nucleus.

56 ine neurons in the ventral PAG (vPAG)/dorsal raphe (DR) region are a potentially critical site for th

57 The dorsal raphe (DR) serotonergic neurons have long been implicate

58 whether a serotonergic input from the dorsal raphe (DR) to ventral tegmental area (VTA) influences vu

59 Conversely, dorsal raphe (DR)-projecting LHb neurons do not show CS-induced

60 in the interfascicular nucleus of the dorsal raphe (DRif), resulting in decreased 5HTergic innervatio

61 h previously described burst activity of the raphe during arousing stimuli.

62 lts suggest that serotonergic afferents from raphe dynamically modulate olfactory processing through

63 We hypothesize that raphe dysfunction contributes to a failure to autoresusc

64 ostnatal life induced by a partial defect in raphe function.

65 To explore retino-raphe functional organization, light-evoked c-fos expres

66 Stimulation of dorsal raphe gamma-aminobutyric acid (GABA) neurons promoted mo

67 to hypercapnia in BN rats is due to altered raphe gene expression and the consequent deficiencies in

68 Further, loss of dorsal raphe GluD1(R)-channels produces an anxiogenic phenotype

69 Bicuspid aortic valves with raphe had a significantly higher prevalence of valve dys

70 Although patients with BAV and raphe had higher mortality rates than patients without,

71 nd serotonin (5-HT) neurons in the medullary raphe have both been proposed to be central respiratory

72 The dorsal raphe ICC value was sensitive to a measurement outlier.

73 increased activity in median but not dorsal raphe, implicating serotonergic signaling through Htr3a

74 activation of 5-HT neurons within the dorsal raphe in females and activation of hypothalamic AVP neur

75 Similarly, in mice, ablation of the raphe increases wakefulness and impairs the homeostatic

76 lei included: cuneiform/subcuneiform, dorsal raphe, locus coeruleus, median raphe, parabrachial compl

77 cuit between the red nucleus and the nucleus raphe magnus.

78 e adult the entire DR and part of the median raphe (MnR) have Fgf8 lineage.

79 InCO(2) increased IL-1beta in the medullary raphe (MR), ventral respiratory column, and cuneate nucl

80 Presynaptic dorsal raphe neuron (DRN) 5-HT1A receptors are known to have a

81 blocked by pharmacological inhibition or by raphe neuron ablation, commissural pathfinding is disrup

82 f persistent pacemaker-type firing of dorsal raphe neurons and regulate dorsal raphe-related behavior

83 the light chain from tetanus toxin (tox) in raphe neurons expressing serotonergic bacterial artifici

84 We found that the raphe neurons extend projections toward midline-crossing

85 alterations in the serotonergic phenotype of raphe neurons have dramatic effects on affective behavio

86 eted different fractions of serotonergic and raphe neurons in mice for tetanus toxin light chain expr

87 that knock-down of htr2a or ablation of the raphe neurons increases ephrinB2a protein levels in comm

88 Action potential firing of serotonin dorsal raphe neurons is driven via alpha1-adrenergic receptors

89 at regulation of serotonin expression in the raphe neurons is modulated in response to the developmen

90 TS, A5 or Locus Coeruleus, no serotoninergic raphe neurons nor any cholinergic neurons in the PPT and

91 monstrate that serotonergic projections from raphe neurons regulate pathfinding of crossing axons.

92 of the acetylation-mimic mutant of Hsp90 in raphe neurons reproduced the behavioral effect of ACY-73

93 We recorded the activity of dorsal raphe neurons while mice experienced a task in which rew

94 ese ideas in the context of rat serotonergic raphe neurons, which fire spontaneously at low frequency

95 n expanded peripheral division of the dorsal raphe nuclear complex appears likely to play a role in t

96 n enlarged peripheral division of the dorsal raphe nuclear complex of the minke whale, all indicate t

97 Serotonin neurons in the dorsal and median raphe nuclei (DR and MR) are clustered into heterogeneou

98 neurons preferentially project to the dorsal Raphe nuclei (DRN).

99 C regions (F1,88 = 5.19; P = .03) and in the raphe nuclei (F1,87 = 7.38; P = .008; R2 = 0.12).

100 FC regions (F1,88 = 0.03; P = .87) or in the raphe nuclei (F1,88 = 0.29; P = .59).

101 ncluding basal ganglia, locus coeruleus, and raphe nuclei (phase II), followed by primary motor corte

102 higher serotonin1A binding potential in the raphe nuclei (RN) is associated with greater lethality o

103 g neurons control sleep via the serotonergic raphe nuclei (RN), a hindbrain structure that is critica

104 The serotonergic raphe nuclei (RNi) connections involve regions of the SM

105 MI) to quantify 5-HT(1A) binding in midbrain raphe nuclei and functional magnetic resonance imaging (

106 anscripts expressed in neurons of the dorsal raphe nuclei and lateral hypothalamus that project to th

107 We conclude that the raphe nuclei are affected in a subgroup of early drug-na

108 The serotonergic raphe nuclei are involved in regulating brain states ove

109 in transporter availability in the brainstem raphe nuclei compared to controls (P < 0.01) and subject

110 Serotonergic neurons in the brainstem raphe nuclei densely innervate the olfactory bulb (OB),

111 the level of involvement of the serotonergic raphe nuclei in early Parkinson's disease is still debat

112 etermine: (i) the integrity of the brainstem raphe nuclei in early Parkinson's disease; and (ii) whet

113 mosensory behaviours driven by the brainstem raphe nuclei into these parallel systems.

114 Brief stimulation of the raphe nuclei led to excitation of tufted cells at rest a

115 Serotonin (5-HT) neurons located in the raphe nuclei modulate a wide range of behaviors by means

116 sms through which 5-HT neurons in the dorsal raphe nuclei modulate amygdala circuits.

117 Serotonin(1A )BPF in the raphe nuclei of suicide attempters was positively correl

118 rogeneity in populations of the serotonergic raphe nuclei of the brainstem reticular formation, with

119 The serotonergic raphe nuclei of the midbrain are principal centers from

120 The raphe nuclei provide serotonergic innervation widely in

121 The dorsal raphe nuclei receive light input from the circadian visu

122 n the striatum, its binding in the brainstem raphe nuclei reflects serotonin transporter availability

123 TP influx rate was observed in the amygdala, raphe nuclei region, caudate nucleus, putamen, hippocamp

124 elevated [11C]DASB binding potential in the raphe nuclei region, caudate nucleus, putamen, thalamus,

125 dbrain but higher uptake in the thalamus and raphe nuclei than control patients.

126 l molecular and neurochemical changes in the raphe nuclei that dysregulate 5-HT neuronal activity and

127 ulate 5-HT neuronal activity in the midbrain raphe nuclei through alpha-amino-3-hydroxy-5-methyl-4-is

128 Serotonin (5-HT) neurons project from the raphe nuclei throughout the brain where they act to main

129 The two raphe nuclei thus give dual innervation within the OB, w

130 find that serotonergic projections from the raphe nuclei to the olfactory bulb dramatically enhance

131 ffinity dihydroergotamine receptors, and the raphe nuclei, a postulated brainstem site of action duri

132 ngulate cortex, nucleus accumbens, thalamus, raphe nuclei, and bed nucleus of the stria terminals.

133 is bilaterally connected with serotoninergic raphe nuclei, and expresses high density of serotonin re

134 rea, the rhabdoid nucleus, the mesencephalic raphe nuclei, and the dorsal tegmental nucleus.

135 the ventral (p<0.0001) and dorsal (p=0.0002) raphe nuclei, caudate (p=0.00015), putamen (p=0.036), th

136 Therefore, the raphe nuclei, in addition to their role in neuromodulati

137 Consistent SERT pathology in raphe nuclei, striatum, thalamus, and hypothalamus and a

138 ially innervate the interpeduncular nucleus, raphe nuclei, substantia nigra pars compacta and ventral

139 Among the brainstem raphe nuclei, the dorsal raphe nucleus (DR) contains the

140 rgic genes that are known to be expressed in raphe nuclei.

141 ing the neural circuitry between the LHb and raphe nuclei.

142 subpopulation of SERT-containing synapses in raphe nuclei.

143 tic acid (5-HIAA), and norepinephrine in the raphe nuclei.

144 laminergic VTA/SNc homologs and serotonergic raphe nuclei.

145 corpus C1, the reticular formation, and the Raphe nuclei.

146 after 0.3 mg/kg of citalopram in the dorsal raphe nucleus (5%), as well as after 0.3 mg/kg of vortio

147 Here we show that 5-HT from the dorsal raphe nucleus (5-HT(DRN)) enhances fear and anxiety and

148 Among the brainstem raphe nuclei, the dorsal raphe nucleus (DR) contains the greatest number of Pet1-

149 e level of three glutamate afferents: dorsal raphe nucleus (DR), pedunculopontine nucleus (PPN), and

150 including the median (MnR) and caudal dorsal raphe nucleus (DRC), may contribute to the behavioral ef

151 proach to isolate the contribution of dorsal raphe nucleus (DRN) 5-HT neurons and 5-HT innervation of

152 We found that activating dorsal raphe nucleus (DRN) 5-HT neurons induced a strong suppre

153 that stimulation of the serotonergic dorsal raphe nucleus (DRN) afferents to the nucleus accumbens (

154 eptor 1 (AdipoR1) is expressed in the dorsal raphe nucleus (DRN) and colocalized with tryptophan hydr

155 ses through axonal collaterals to the dorsal raphe nucleus (DRN) and SC.

156 The dorsal raphe nucleus (DRN) and the median raphe nucleus (MRN) a

157 edial prefrontal cortex (mPFC) in the dorsal raphe nucleus (DRN) are of particular interest, in part,

158 edial prefrontal cortex (mPFC) to the dorsal raphe nucleus (DRN) induced fast anxiolytic effects.

159 The dorsal raphe nucleus (DRN) is an important brain area for body-

160 The dorsal raphe nucleus (DRN) is an important source of neuromodul

161 , we discovered that the serotonergic dorsal raphe nucleus (DRN) mediates short-term locomotor learni

162 on activation of serotonergic (5-HT) dorsal raphe nucleus (DRN) neurons that project to the basolate

163 5-HT neurons in the dorsal raphe nucleus (DRN) often fire locked to sensory stimuli

164 ow short- and long-term activation of dorsal raphe nucleus (DRN) serotonergic neurons induces robust

165 -command Mauthner cells also activate dorsal raphe nucleus (DRN) serotonergic neurons, which project

166 s that median raphe nucleus (MRN) and dorsal raphe nucleus (DRN) serotonergic projections differentia

167 ions and is extensively innervated by dorsal raphe nucleus (DRN) serotonin (5-hydroxytryptamine [5-HT

168 also assayed these gene levels in the dorsal raphe nucleus (DRN) with RNAScope.

169 mbined optogenetic stimulation of the dorsal raphe nucleus (DRN) with wide-field calcium imaging, ext

170 TrkB are both highly expressed in the dorsal raphe nucleus (DRN), a brain region that has been sugges

171 In the dorsal raphe nucleus (DRN), feedback activation by Galphai/o -c

172 ns in the dorsolateral portion of the dorsal raphe nucleus (DRN), hereafter DRN(Vgat) neurons, are ac

173 functional role for DA neurons in the dorsal raphe nucleus (DRN), in which we observe synaptic change

174 nfralimbic prefrontal cortex (PFC) or dorsal raphe nucleus (DRN), prevented disruption of DRL perform

175 The dorsal raphe nucleus (DRN), the major source of serotonergic in

176 of the three target areas as follows: dorsal raphe nucleus (DRN), ventral tegmental area (VTA), or ro

177 e ventral tegmental area (VTA) to the dorsal raphe nucleus (DRN), with differential mu-opioid recepto

178 omedial prefrontal cortex (vmPFC) and dorsal raphe nucleus (DRN).

179 otonin (5-HT) and GABA neurons of the dorsal raphe nucleus (DRN).

180 al amygdala (BA) 5-HT inputs from the dorsal raphe nucleus (DRN).

181 H2), in the ventral subnucleus of the dorsal raphe nucleus (DRv).

182 b), interpeduncular nucleus (IP), and median raphe nucleus (MnR).

183 We tested the hypothesis that median raphe nucleus (MRN) and dorsal raphe nucleus (DRN) serot

184 he dorsal raphe nucleus (DRN) and the median raphe nucleus (MRN) are known to densely innervate the O

185 whether functional connectivity (FC) of the raphe nucleus (RN), the major source of most serotonergi

186 urons to serotonergic neurons in the ventral raphe nucleus (vRN).

187 essed downstream neurons in the serotonergic raphe nucleus and caused behavioral passivity, whereas i

188 uit from the lateral hypothalamus and dorsal raphe nucleus and defined a discrete subset of transcrip

189 Here, we show that the raphe nucleus and its serotonergic projections regulate

190 sing the nucleus accumbens shell, the dorsal raphe nucleus and the medial prefrontal cortex.

191 unknown whether BDNF and TrkB in the dorsal raphe nucleus are involved in these processes.

192 ess, we show that 5-HT neurons in the dorsal raphe nucleus are less responsive to stimulation.

193 Here, we demonstrate that the dorsal raphe nucleus DA neurons are critical modulators of beha

194 nography, we observed time-delineated dorsal raphe nucleus dopaminergic (DRN(DA)) activity upon expos

195 Finally, blocking OT receptors in the dorsal raphe nucleus during estrogen withdrawal prevented the h

196 lls or selectively in the area of the dorsal raphe nucleus failed to form an aversion to formalin-ind

197 vation of serotonergic neurons in the dorsal raphe nucleus increases active coping with inescapable s

198 The dorsal raphe nucleus is the predominant source of central serot

199 evoked serotonin transmission in the dorsal raphe nucleus mediated by metabotropic 5-HT1A autorecept

200 Deakin and Graeff argued that the median raphe nucleus normally acts to inhibit consolidation of

201 -B, and tryptophan hydroxylase in the dorsal raphe nucleus of highly perseverative rats.

202 Serotonin neurons located in the raphe nucleus of the hindbrain have crucial roles in reg

203 ced GR translocation were observed in dorsal raphe nucleus of vulnerable mice after chronic social de

204 Here, we show in the mouse that raphe nucleus serotonin neurons activate ventral tegment

205 development of ruminations, while the dorsal raphe nucleus system is engaged by distal cues predictiv

206 cular nucleus of the hypothalamus and dorsal raphe nucleus to increase anxiety-like behavior during t

207 inobutyric acidergic pathway from the dorsal raphe nucleus to the NAcSh to influence behavioral respo

208 uccessful loss-avoidance although the median raphe nucleus was not found to be underactive.

209 rder is associated with an overactive dorsal raphe nucleus with overactive projections to the amygdal

210 grey and striatum, and an underactive median raphe nucleus with underactive projections to the hippoc

211 he stria terminalis, amygdala, habenula, and raphe nucleus), all of which express mu opioid receptors

212 the nucleus accumbens (NAC) shell and dorsal raphe nucleus, and found that disruption of NF-kappaB-ex

213 mentation in serotonin neurons of the dorsal raphe nucleus, and long-term Ovx monkeys had fewer serot

214 d much later in basolateral amygdala, dorsal raphe nucleus, and the substantia nigra pars compacta.

215 Here, we show that neurons in the dorsal raphe nucleus, expressing vesicular transporters for GAB

216 periaqueductal gray, area postrema, pontine raphe nucleus, gracile nucleus, spinal trigeminal nucleu

217 noradrenergic locus coeruleus and the dorsal raphe nucleus, in parallel with decreased DNA methylatio

218 In the dorsal raphe nucleus, it is known that serotonin release activa

219 hypothalamic area, trochlear nucleus, dorsal raphe nucleus, medial lemniscus, pontine nuclei, vagus n

220 one in anterior insula and one in the dorsal raphe nucleus, that track global reward state as well as

221 eA is reciprocally connected with the dorsal raphe nucleus, the main source of serotonin (5-HT) in th

222 A receives dense innervation from the dorsal raphe nucleus, the major source of 5-HT, and expresses 5

223 tonergic (5-HT(+)) neuron-enriched embryonic raphe nucleus-derived neural stem cells/progenitors (RN-

224 Consequently, grafted raphe nucleus-derived neural stem cells/progenitors acte

225 anted serotonergic neuron enriched embryonic raphe nucleus-derived neural stem cells/progenitors into

226 -releasing factor (CRF) regulates the dorsal raphe nucleus-serotonin (DRN-5-HT) system during stress

227 als in the NAcSh originating from the dorsal raphe nucleus.

228 ng in amygdala, caudate, putamen, and median raphe nucleus.

229 R translocation were performed in the dorsal raphe nucleus.

230 ncrease in OT receptor density in the dorsal raphe nucleus.

231 itries, including striatum, hippocampus, and raphe nucleus.

232 The dorsal raphe nucleus/ periaqueductal grey region of the midbrai

233 n additional subdivision of the serotonergic raphe obscurus nucleus, and the expansion of the superio

234 d the vertical asymmetry across the temporal raphe of the deep retinal layer vessel density, using sw

235 brown fat via a descending projection to the raphe pallidus (RPa).

236 muscarinic cholinergic inhibition of rostral raphe pallidus (rRPa) neurons influences thermogenesis o

237 cholinergic input to neurons in the rostral raphe pallidus (rRPa), the site of sympathetic premotor

238 eus [PaMP]) and autonomic (rostral medullary raphe pallidus [RPa]) responses were targeted with disti

239 the neuroaxis with highest densities in the raphe pallidus nucleus, nucleus of the solitary tract, p

240 c brain regions, namely the locus coeruleus, raphe pallidus, and paraventricular nucleus of the hypot

241 rons to a key site for fever production, the raphe pallidus.

242 iform, dorsal raphe, locus coeruleus, median raphe, parabrachial complex, pontine oralis, pedunculopo

243 dissection of inputs originating from dorsal raphe, pedunculopontine, and subthalamic nuclei were tes

244 a suppression of an inhibitory NPVF-ventral raphe peptidergic projection.

245 Both calcified raphe plus excess leaflet calcification were found in 26

246 T-ir cell cluster, and an extensive inferior raphe population.

247 d down 5-HT1A receptors in either the dorsal raphe (presynaptic autoreceptors) or the hippocampus (a

248 a selective FKBP51 inhibitor into the dorsal raphe prior to repeated forced swim stress decreased res

249 In turn, the raphe receives a vast array of synaptic inputs, and a re

250 , genetic ablation of 5-HT production by the raphe reduces sleep, sleep depth, and the homeostatic re

251 harmacological inhibition or ablation of the raphe reduces sleep, while optogenetic stimulation incre

252 We found that the median raphe region (MnR) is important for regulating hippocamp

253 of dorsal raphe neurons and regulate dorsal raphe-related behavior.

254 es often have abnormalities of the brainstem raphe serotonergic (5-HT) system.

255 Both dorsal raphe serotonergic activity during aversive reinforcemen

256 Finally, optogenetically stimulating raphe serotonergic afferents in the OB had heterogeneous

257 opmental failure of laterally located dorsal raphe serotonergic neurons and changes in serotonergic i

258 ing of the pathophysiological role of dorsal raphe serotonergic neurons in different species and the

259 ers targeted different portions of medullary raphe serotonergic, tryptophan hydroxylase 2 (Tph2)(+) n

260 coeruleus norepinephrine (LC-NE) and dorsal raphe serotonin (DR 5-HT) systems.

261 vironments, and that movement-related dorsal raphe serotonin neural dynamics inverted in high-threat

262 In mice, we found that stimulation of dorsal raphe serotonin neurons suppressed movement in low- and

263 ings in mice to study a population of dorsal raphe serotonin neurons, whose activity we could link to

264 There was no association between raphe serotonin transporter availability and fatigue, de

265 n's disease subgroup had significantly lower raphe serotonin transporter availability but less severe

266 arkinson's disease patients and that reduced raphe serotonin transporter availability is associated w

267 Raphe serotonin transporter availability over the entire

268 In tremulous patients, raphe serotonin transporter availability was also associ

269 early Parkinson's disease; and (ii) whether raphe serotonin transporter levels correlate with severi

270 Dorsal raphe serotonin's unique contribution provides a neural

271 Higher brainstem raphe serotonin(1A) BPF would be consistent with lower l

272 Higher brainstem raphe serotonin(1A)BPF observed in higher-lethality suic

273 basal forebrain (acetylcholine; ACh), dorsal raphe (serotonin; 5HT), and singly labeled Fos(+) cells

274 T1A receptors in hippocampus, but not dorsal raphe, significantly decreased the antidepressant-like e

275 ession of optical reporters to visualize how raphe stimulation alters sensory responses in two classe

276 In PG and SA cells, brief (1-4 s) raphe stimulation elicited a large increase in the magni

277 rast, in MT cells imaged from the dorsal OB, raphe stimulation elicited a strong increase in resting

278 te vocal-acoustic communication, to redefine raphe subgroups based on both stringent neuroanatomical

279 stribution in various teleosts, serotonergic raphe subgroups in fish are not well defined and therefo

280 We uncover a dorsal raphe subpopulation with persistent activity that robust

281 ation that reveals the true structure of the raphe system, which consists of a raphe canal raised on

282 ppropriately described as part of the median raphe system.

283 erotonergic projection neurons in the dorsal raphe that project to the anterior hypothalamus and may

284 with prior studies of IP projections to the raphe, these results form an emerging map of the habenul

285 e ICC values ranged from -0.13 in the dorsal raphe to 0.88 in the caudate nucleus.

286 rodents, whereas monkeys and humans showed a raphe to cerebellum ratio of approximately 3.

287 may in turn arise from disrupted linkage in raphe to hippocampus serotonergic circuitry.

288 Medullary raphe transcriptome comparisons revealed lower expressio

289 In particular, raphe Trh mRNA and peptide levels were significantly red

290 ssociation between BAV morphologic findings (raphe vs nonraphe) and the degree of valve dysfunction,

291 Quantitation of raphe was affected by the resolution of the PET scanners

292 The presence of raphe was also associated with increased rates of aortic

293 international BAV registry, the presence of raphe was associated with a higher prevalence of signifi

294 tes than patients without, the presence of a raphe was not independently associated with increased al

295 , on multivariable analysis, the presence of raphe was not significantly associated with all-cause mo

296 Mefway in cortical regions, hippocampus, and raphe was observed across all species.

297 .0%] male), 1881 (88.8%) had BAV with fusion raphe, whereas 237 (11.2%) had BAV without raphe.

298 d in the regulation of anxiety is the dorsal raphe, which contains different subtypes of serotonergic

299 itzschia, with bridges (fibulae) beneath the raphe, which is marginal.

300 the rhombomeric segments 2-3 of the rostral raphe, which participate in high-order brain functions.