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1 etected in the basal forebrain or the dorsal raphe nucleus.
2 ca, supramammillary nuclei (SUM), and median raphe nucleus.
3 reticular formation, including the inferior raphe nucleus.
4 thin the dorsal portion of the caudal dorsal raphe nucleus.
5 l raphe nucleus (DRN) and part of the median raphe nucleus.
6 in serotonin-producing neurons of the dorsal raphe nucleus.
7 dunculopontine tegmental nucleus, and dorsal raphe nucleus.
8 haviors after microinjection into the median raphe nucleus.
9 elated to the serotonin system in the dorsal raphe nucleus.
10 ncrease in OT receptor density in the dorsal raphe nucleus.
11 l reticular nucleus, hypoglossal nucleus and raphe nucleus.
12 et of serotonergic neurons within the dorsal raphe nucleus.
13 itries, including striatum, hippocampus, and raphe nucleus.
14 5-HT transmission at the level of the dorsal raphe nucleus.
15 al area, interfascicular nucleus, and dorsal raphe nucleus.
16 hat is activated by 8-OH-DPAT, in the dorsal raphe nucleus.
17 nergic (5-HTergic) neurons within the dorsal raphe nucleus.
18 ther areas such as the cerebellum and dorsal raphe nucleus.
19 activity of serotonergic cells of the dorsal raphe nucleus.
20 urons in the rat median raphe but not dorsal raphe nucleus.
21 al nucleus of the amygdala and in the dorsal raphe nucleus.
22 e and the alpha4 nAChR subunit in the dorsal raphe nucleus.
23 located in the ventral portion of the dorsal raphe nucleus.
24 omedial subregion of the intermediate dorsal raphe nucleus.
25 dinal fasciculi and extended into the median raphe nucleus.
26 eptors can induce 5-HT release in the dorsal raphe nucleus.
27 any serotonergic group other than the dorsal raphe nucleus.
28 tine binding was also observed in the median raphe nucleus.
29 ions, but was markedly reduced in the dorsal raphe nucleus.
30 assical 5-HT neurones recorded in the dorsal raphe nucleus.
31 of the serotonergic perikarya in the dorsal raphe nucleus.
32 als in the NAcSh originating from the dorsal raphe nucleus.
33 ng in amygdala, caudate, putamen, and median raphe nucleus.
34 R translocation were performed in the dorsal raphe nucleus.
35 l nucleus of the hypothalamus and the dorsal raphe nucleus.
37 after 0.3 mg/kg of citalopram in the dorsal raphe nucleus (5%), as well as after 0.3 mg/kg of vortio
39 droxytryptamine (5-HT) neurons in the dorsal Raphe nucleus (5-HT(DRN)) regulate different types of fe
40 nculopontine tegmental nucleus (86%); dorsal raphe nucleus (53%); dorsal medial periaqueductal gray (
41 ontine tegmental nucleus (55.7%), and dorsal raphe nucleus (54.0%) but not in the nucleus locus coeru
42 he firing rate of 5-HT neurons in the dorsal raphe nucleus, a major source of serotonergic input to t
43 identified synaptic contacts, and the dorsal raphe nucleus, a somatodendritic region with rare synapt
44 he stria terminalis, amygdala, habenula, and raphe nucleus), all of which express mu opioid receptors
45 uch as the ventral tegmental area and dorsal raphe nucleus among others, that are implicated in the r
46 essed downstream neurons in the serotonergic raphe nucleus and caused behavioral passivity, whereas i
47 uit from the lateral hypothalamus and dorsal raphe nucleus and defined a discrete subset of transcrip
51 xytryptamine (5,7-DHT) lesions of the dorsal raphe nucleus and median raphe nucleus prevents LiCl-ind
52 e on the levels of 5-HT1B mRNA in the dorsal raphe nucleus and several postsynaptic brain areas using
54 ojecting to the amygdala, such as the dorsal raphe nucleus and ventral tegmental area, providing evid
55 ), separated for 5-HT autoinhibition (dorsal raphe nucleus) and local inhibition (heteroreceptors in
56 gic tuberomammillary nucleus, serotoninergic raphe nucleus, and dopaminergic ventral tegmental area.
57 the nucleus accumbens (NAC) shell and dorsal raphe nucleus, and found that disruption of NF-kappaB-ex
60 mentation in serotonin neurons of the dorsal raphe nucleus, and long-term Ovx monkeys had fewer serot
61 alamus, lateral parabrachial nucleus, dorsal raphe nucleus, and nucleus accumbens shell), all of whic
62 e amygdala, brainstem in the vicinity of the raphe nucleus, and reticular formation, hypothalamus, an
63 d much later in basolateral amygdala, dorsal raphe nucleus, and the substantia nigra pars compacta.
64 d afferents from the locus coeruleus, dorsal raphe, nucleus annularis, central superior nucleus, pont
65 tion of responsive neurons within the dorsal raphe nucleus are consistent with the hypothesis that en
68 ased by electrical stimulation of the dorsal raphe nucleus attenuated odor-evoked responses without d
69 ulo-parieto-occipital regions and the dorsal raphe nucleus, but intensified Salience Network connecti
70 effect on c-Fos expression within the median raphe nucleus, consistent with the hypothesis that Ucn 2
71 atment enhances 5-HTP accumulation in dorsal raphe nucleus, cortex and caudate nucleus, but not in me
73 tonergic (5-HT(+)) neuron-enriched embryonic raphe nucleus-derived neural stem cells/progenitors (RN-
75 anted serotonergic neuron enriched embryonic raphe nucleus-derived neural stem cells/progenitors into
76 nography, we observed time-delineated dorsal raphe nucleus dopaminergic (DRN(DA)) activity upon expos
80 HT) containing neurons located in the dorsal raphe nucleus (DR) comprise the main source of forebrain
82 Among the brainstem raphe nuclei, the dorsal raphe nucleus (DR) contains the greatest number of Pet1-
89 onal neuroanatomy of the serotonergic dorsal raphe nucleus (DR) to propose such a mechanistic account
90 rotonin transporters within the human dorsal raphe nucleus (DR) were determined by quantitative autor
91 tive disorders through effects on the dorsal raphe nucleus (DR), a source of forebrain-projecting ser
92 e level of three glutamate afferents: dorsal raphe nucleus (DR), pedunculopontine nucleus (PPN), and
93 in the ventral tegmental area (VTA), dorsal raphe nucleus (DR), periaqueductal grey area (PAG) and l
94 tingly, the RMTg also projects to the dorsal raphe nucleus (DR), which also receives direct LHb proje
95 serotonergic innervation is from the dorsal raphe nucleus (DR), which contains both serotonin and GA
96 quent responses of an anxiety-related dorsal raphe nucleus (DR)-basolateral amygdala system to pharma
100 including the median (MnR) and caudal dorsal raphe nucleus (DRC), may contribute to the behavioral ef
102 proach to isolate the contribution of dorsal raphe nucleus (DRN) 5-HT neurons and 5-HT innervation of
104 that stimulation of the serotonergic dorsal raphe nucleus (DRN) afferents to the nucleus accumbens (
106 eptor 1 (AdipoR1) is expressed in the dorsal raphe nucleus (DRN) and colocalized with tryptophan hydr
107 Injections of rhodamine-B into the dorsal raphe nucleus (DRN) and Fluoro-Gold into the lateral gen
109 uring 5-HT neurons that will form the dorsal raphe nucleus (DRN) and part of the median raphe nucleus
110 f distribution (V(T)) for presynaptic dorsal raphe nucleus (DRN) and postsynaptic cortical regions.
113 also examined two control areas, the dorsal raphe nucleus (DRN) and the periaqueductal gray (PAG), i
114 serotonin (5-HT) in 5-HT cells of the dorsal raphe nucleus (DRN) and to determine which 5-HT receptor
115 lopontine tegmentum, up to 4 h in the dorsal raphe nucleus (DRN) and up to 6 h in the locus coeruleus
117 the periaqueductal gray (PAG) and the dorsal raphe nucleus (DRN) are involved in morphine-induced c-F
118 nd serotonergic (5-HT) neurons of the dorsal raphe nucleus (DRN) are mostly active during waking and
119 edial prefrontal cortex (mPFC) in the dorsal raphe nucleus (DRN) are of particular interest, in part,
120 (5-HT) from neurons within the caudal dorsal raphe nucleus (DRN) both at the time of IS and later beh
124 ow doses of CRF administered into the dorsal raphe nucleus (DRN) decrease DRN unit activity and serot
125 one (CRH) receptors within the caudal dorsal raphe nucleus (DRN) during inescapable tailshock (IS) ha
126 B), but not GABA(A), receptors in the dorsal raphe nucleus (DRN) escalated aggressive behaviors.
127 direct pathway from the retina to the dorsal raphe nucleus (DRN) has been demonstrated in both albino
128 ial projection from the retina to the dorsal raphe nucleus (DRN) has been demonstrated in the Chilean
129 y, local injection of morphine in the dorsal raphe nucleus (DRN) has been shown to increase serotonin
132 ion in 5-HT1A receptor domains in the dorsal raphe nucleus (DRN) in brain slices and in vivo, which i
133 IOD) measures obtained throughout the dorsal raphe nucleus (DRN) in Mongolian gerbils at selected tim
136 edial prefrontal cortex (mPFC) to the dorsal raphe nucleus (DRN) induced fast anxiolytic effects.
143 edial prefrontal cortex (PFC) and the dorsal raphe nucleus (DRN) may be dysfunctional in major depres
144 hesized that GABAergic neurons in the dorsal raphe nucleus (DRN) may participate in socioaffective re
145 , we discovered that the serotonergic dorsal raphe nucleus (DRN) mediates short-term locomotor learni
146 lysis was used to analyze the role of dorsal raphe nucleus (DRN) neurons in regulating the sleep-waki
147 on activation of serotonergic (5-HT) dorsal raphe nucleus (DRN) neurons that project to the basolate
149 Thus, we used microdialysis in the dorsal raphe nucleus (DRN) of freely behaving rats to study the
151 Recent evidence suggests that the dorsal raphe nucleus (DRN) of the brainstem is a collection of
153 ed that electrical stimulation of the dorsal raphe nucleus (DRN) or median raphe nucleus (MRN) in ham
154 ptors regulate serotonin release from dorsal raphe nucleus (DRN) projections throughout rat forebrain
156 ) in the locus coeruleus (LC) and the dorsal raphe nucleus (DRN) regions of postmortem human brains.
157 ow short- and long-term activation of dorsal raphe nucleus (DRN) serotonergic neurons induces robust
158 -command Mauthner cells also activate dorsal raphe nucleus (DRN) serotonergic neurons, which project
159 s that median raphe nucleus (MRN) and dorsal raphe nucleus (DRN) serotonergic projections differentia
160 (alpha1-ARs) control the activity of dorsal raphe nucleus (DRn) serotonin (5-HT) neurons and play cr
162 ions and is extensively innervated by dorsal raphe nucleus (DRN) serotonin (5-hydroxytryptamine [5-HT
163 ll patch-clamp recordings in an acute dorsal raphe nucleus (DRN) slice preparation, we report that or
164 The serotonin (5-HT) pathway from the dorsal raphe nucleus (DRN) to the medial prefrontal cortex (mPF
165 yric acid (GABA) projections from the dorsal raphe nucleus (DRN) to the NAcSh (DRN -> NAcSh) is the n
166 yric acid (GABA) projections from the dorsal raphe nucleus (DRN) to the NAcSh (DRN NAcSh) is the neur
167 ically identified 5-HT cells from the dorsal raphe nucleus (DRN) were examined with whole-cell record
169 mbined optogenetic stimulation of the dorsal raphe nucleus (DRN) with wide-field calcium imaging, ext
170 TrkB are both highly expressed in the dorsal raphe nucleus (DRN), a brain region that has been sugges
171 erformed single-unit recording in the dorsal raphe nucleus (DRN), a major source of serotonin, and th
172 PFC cells projecting to the brainstem dorsal raphe nucleus (DRN), a serotonergic nucleus implicated i
173 the periaqueductal gray (PAG) and the dorsal raphe nucleus (DRN), adjoining mesencephalic cell groups
175 7, t = 2.57, df = 7, P = 0.04) in the dorsal raphe nucleus (DRN), and not different between suicides
176 of the KOR antagonist norBNI into the dorsal raphe nucleus (DRN), blocked aversive responses to the K
177 tivity of serotonergic neurons in the dorsal raphe nucleus (DRN), but the mechanisms involved have no
179 ns in the dorsolateral portion of the dorsal raphe nucleus (DRN), hereafter DRN(Vgat) neurons, are ac
180 functional role for DA neurons in the dorsal raphe nucleus (DRN), in which we observe synaptic change
181 nfralimbic prefrontal cortex (PFC) or dorsal raphe nucleus (DRN), prevented disruption of DRL perform
182 locus of serotonergic neurons is the dorsal raphe nucleus (DRN), providing brain-wide serotonergic i
183 IS activates serotonin neurons in the dorsal raphe nucleus (DRN), rendering them hyperexcitable.
184 eable binding potential (BPND) in the dorsal raphe nucleus (DRN), the core area of 5-HT synthesis, an
186 of the three target areas as follows: dorsal raphe nucleus (DRN), ventral tegmental area (VTA), or ro
187 la receive 5-HT innervations from the dorsal raphe nucleus (DRN), we determined if PDA lesions might
188 any regions of the CNS, including the dorsal raphe nucleus (DRN), where serotonin (5-HT) neurons are
189 e ventral tegmental area (VTA) to the dorsal raphe nucleus (DRN), with differential mu-opioid recepto
190 or brain serotonin (5-HT) system, the dorsal raphe nucleus (DRN)-5-HT system as a point of convergenc
203 including 5-HT2c-Rs, are found in the dorsal raphe nucleus (DRN); however, the function of 5-HT2c-Rs
206 Finally, blocking OT receptors in the dorsal raphe nucleus during estrogen withdrawal prevented the h
207 hat serotonergic changes occur in the dorsal raphe nucleus during inescapable shock and that such cha
208 al tuberal nucleus, substantia nigra, dorsal raphe nucleus, Edinger-Westphal nucleus, and the locus c
210 (SVc) and interpolaris (SVi), and the dorsal raphe nucleus exhibited a greater number of c-Fos labele
211 Here, we show that neurons in the dorsal raphe nucleus, expressing vesicular transporters for GAB
212 lls or selectively in the area of the dorsal raphe nucleus failed to form an aversion to formalin-ind
213 periaqueductal gray, area postrema, pontine raphe nucleus, gracile nucleus, spinal trigeminal nucleu
215 tress increases 5-HTP accumulation in median raphe nucleus, hippocampus, cortex, and nucleus accumben
216 f previous studies of the role of the dorsal raphe nucleus in sleep, because many of those experiment
217 al gray substance of the midbrain and dorsal raphe nucleus in the midbrain; and parabrachial nucleus
219 noradrenergic locus coeruleus and the dorsal raphe nucleus, in parallel with decreased DNA methylatio
220 balance of responses within the serotonergic raphe nucleus, including a coordination of corticotropin
221 vation of serotonergic neurons in the dorsal raphe nucleus increases active coping with inescapable s
223 clei, laterodorsal tegmental nucleus, dorsal raphe nucleus, interpeduncular nucleus, medial mammillar
224 d reduction in 5-HT7 receptors in the dorsal raphe nucleus is an important neurochemical mechanism le
226 raffic in pathways emanating from the dorsal raphe nucleus is controlled by 5-HT(1) autoreceptors.
229 inent ipsilateral labeling within the dorsal raphe nucleus, just ventral to the cerebral aqueduct.
230 i of pontomesencephalic central gray (dorsal raphe nucleus, laterodorsal tegmental nucleus, and Barri
231 s in the following brain-stem nuclei: dorsal raphe nucleus, locus coeruleus, lateral and medial parab
232 al nucleus, Edinger-Westphal nucleus, dorsal raphe nucleus, locus coeruleus, or hypoglossal nucleus.
233 hypothalamic area, trochlear nucleus, dorsal raphe nucleus, medial lemniscus, pontine nuclei, vagus n
234 evoked serotonin transmission in the dorsal raphe nucleus mediated by metabotropic 5-HT1A autorecept
235 tonergic neurons in the mesencephalic median raphe nucleus (MnR) also give rise to a major SCN affere
238 strate that serotonergic cells in the median raphe nucleus (MR) project to the SCN and that serotoner
239 the GABA-A agonist muscimol into the median raphe nucleus (MR) result in large increases in the inta
242 tion of the forebrain arises from the median raphe nucleus (MRN) and dorsal raphe nucleus (DRN).
243 he dorsal raphe nucleus (DRN) and the median raphe nucleus (MRN) are known to densely innervate the O
244 of the dorsal raphe nucleus (DRN) or median raphe nucleus (MRN) in hamsters evoked 5-HT release in t
245 llowing electrical stimulation of the median raphe nucleus (MRN) in unanesthetized prenatally malnour
248 eral geniculate nuclei [LGN], and the median raphe nucleus [MRN] and dorsal raphe nucleus [DRN]).
249 lamus (VMH) (bilaterally, n = 6), the dorsal raphe nucleus (n = 3), and the lateral ventricle (n = 3)
250 Deakin and Graeff argued that the median raphe nucleus normally acts to inhibit consolidation of
251 roject to the ventral tegmental area, dorsal raphe nucleus, nucleus accumbens, and spinal cord, and o
255 tral and dorsal tegmental nuclei, the median raphe nucleus of the pons, the ventral part of the medul
256 ced GR translocation were observed in dorsal raphe nucleus of vulnerable mice after chronic social de
258 on) failed to inhibit activity in the dorsal raphe nucleus or use the ventromedial prefrontal cortex,
261 erent aspects of 5-HT function in the dorsal raphe nucleus presenting new therapeutic opportunities.
262 sions of the dorsal raphe nucleus and median raphe nucleus prevents LiCl-induced conditioned disgust
263 ude that burst-firing neurones in the dorsal raphe nucleus project to the forebrain, and each spike g
264 ct to all four PAG columns, while the dorsal raphe nucleus projects only to the ventrolateral and lat
265 ptic somatodendritic autoreceptors on dorsal raphe nucleus relative to each of the other three groups
267 whether functional connectivity (FC) of the raphe nucleus (RN), the major source of most serotonergi
268 mrEn1-Pet1(7) in the mouse brainstem median raphe nucleus segregates serotonin from VGLUT3 (also kno
269 A subgroup of approximately 25% of dorsal raphe nucleus serotonergic neurons in cat was strongly a
271 -releasing factor (CRF) regulates the dorsal raphe nucleus-serotonin (DRN-5-HT) system during stress
272 nergic neurons in the locus ceruleus, dorsal raphe nucleus, substantia nigra, and ventral tegmental a
273 development of ruminations, while the dorsal raphe nucleus system is engaged by distal cues predictiv
275 de within serotonergic neurons of the dorsal raphe nucleus that mediates depressive and drug-seeking
276 tivation of serotonergic cells in the dorsal raphe nucleus that would normally be produced by uncontr
277 one in anterior insula and one in the dorsal raphe nucleus, that track global reward state as well as
278 orks for the medial reticular formation, the raphe nucleus, the glossopharyngeal nuclei, and the Purk
279 eA is reciprocally connected with the dorsal raphe nucleus, the main source of serotonin (5-HT) in th
280 A receives dense innervation from the dorsal raphe nucleus, the major source of 5-HT, and expresses 5
281 cular nucleus of the hypothalamus and dorsal raphe nucleus to increase anxiety-like behavior during t
282 otonergic neurons projecting from the dorsal raphe nucleus to pontine cholinergic/cholinoceptive cell
283 inobutyric acidergic pathway from the dorsal raphe nucleus to the NAcSh to influence behavioral respo
286 rter mRNA hybridization signal in the dorsal raphe nucleus was only slightly reduced after 5,7-dihydr
290 in the ventral portion of the caudal dorsal raphe nucleus were markedly potentiated in slices prepar
291 lar levels of serotonin (5-HT) in the dorsal raphe nucleus were measured by in vivo microdialysis.
294 alR2-binding sites by 50%, in the rat dorsal raphe nucleus, where galanin coexists with serotonin.
295 shock elevated galanin mRNA levels in dorsal raphe nucleus, whereas sleep deprivation increased galan
296 of these receptors specifically from dorsal raphe nucleus, which provides serotonergic (5-hydroxytry
297 on, their close relationship with the dorsal raphe nucleus will require reassessment of previous stud
298 ty of serotonergic neurons in the rat dorsal raphe nucleus with extracellular single unit recording i
299 rder is associated with an overactive dorsal raphe nucleus with overactive projections to the amygdal
300 grey and striatum, and an underactive median raphe nucleus with underactive projections to the hippoc