ライフサイエンスコーパス: reactivity

1 tudies, which fully address multi-spin-state reactivity.

2 ct of the selenium atom on EBS photochemical reactivity.

3 is suitable as screening assay to detect CHX reactivity.

4 ns, in part due to concerns about off-target reactivity.

5 tions of the aryl rings can lead to improved reactivity.

6 they are closely related, due to their high reactivity.

7 ding sites and revealed strongly reduced IgE reactivity.

8 and also regulated astrocyte and microglial reactivity.

9 the effect of coordination on structure and reactivity.

10 stand, even to predict, the chemical organic reactivity.

11 oid dimers of nonplanar subunits with biased reactivity.

12 ing subsurface divalent silicate carbonation reactivity.

13 is a fruitful arena for the discovery of new reactivity.

14 escent naive T cell subset and enhanced self-reactivity.

15 inct from TIL subsets enriched for antitumor reactivity.

16 ssels, a phenomenon known as cerebrovascular reactivity.

17 -were designed to leverage both affinity and reactivity.

18 dynamic and kinetic challenges for promoting reactivity.

19 but less so for compounds with intermediate reactivity.

20 cally different groups affords diverse thiol reactivity.

21 ford primarily beta-hydride elimination side reactivity.

22 ta composition and higher local inflammatory reactivity.

23 ith the receptor, and confirmed murine cross-reactivity.

24 h their unusual structures and high chemical reactivity(1).

25 Based on reactivity, 10 proteins were analyzed in a secondary scr

26 nti-TNF conversely decreasing right amygdala reactivity (across emotional valence) (p = 0.033).

27 hracene 1 was found to display unprecedented reactivity, acting as a convenient and highly effective

28 ur results suggest that differences in cross-reactivity after influenza vaccination should be expecte

29 n = 43) and non-AMR (n = 21) were tested for reactivity against a panel of 44 non-HLA autoantigens.

30 rough the discovery of antibodies and T-cell reactivity against citrullinated peptides.

31 T cell reactivity against SARS-CoV-2 was observed in unexposed

32 pression during follow-up showed no in vitro reactivity against stimulatory donor blood cells on day

33 s for human onchocerciasis are based on IgG4 reactivity against the OV-16 antigen, with sensitivities

34 latory donor blood cells on day 360, whereas reactivity against third-party cells was still preserved

35 We compared the level of antibody reactivity among healthy blood donors from 2 widely sepa

36 IgE reactivity analysis in 28 patients allergic to chicken m

37 ave rationalized the observed differences in reactivities and designed mutant enzymes that reverse pe

38 The IgE-reactivity and allergenic activity of the hybrid cycloph

39 rivaroxaban effect that impacts on platelet reactivity and arterial thrombosis.

40 ng sensitivity, specificity, potential cross-reactivity and cross-protectivity, the diagnostic value

41 The relationship between T cell reactivity and early PD in two independent cohorts showe

42 ,3-diyls are fascinating due to their unique reactivity and electronic properties.

43 t may be generally applicable in controlling reactivity and enantioselectivity in intermolecular radi

44 ctures are generated based on predicted site reactivity and filtered on the basis of physical and thr

45 Ps in their post-use phases in which surface reactivity and hazard potential can be greatly altered b

46 cific structural, conformational, stability, reactivity and interaction features of fluorinated sugar

47 rties of bnAb variable regions, such as poly-reactivity and long antigen-binding loops, which are usu

48 It is also synonymous with a high chemical reactivity and low reduction potential.

49 cle provides a comprehensive overview of the reactivity and methodological diversification of metal-c

50 the sequence of events, controlling SAM dual reactivity and preventing unwanted radical-based chemist

51 Through direct comparison, we illustrate the reactivity and selectivity advantages of this approach r

52 al synthesis due to insurmountable issues of reactivity and selectivity associated with all previousl

53 of stereoelectronic interactions to control reactivity and selectivity has a long history in chemist

54 These properties well explain the reactivity and selectivity of SNZVI during the reductive

55 e key mechanistic aspects that influence the reactivity and selectivity of the reaction, comparing th

56 y a fundamental role in determining chemical reactivity and selectivity.

57 and conformation while modulating substrate reactivity and selectivity.

58 gand system is crucial for the observed high reactivity and site selectivity.

59 Despite recent advances, reactivity and site-selectivity remain significant obsta

60 Combining reactivity and spectroscopic results on these four types

61 Superior reactivity and stereoselectivity are realized for the fi

62 that might influence stress and inflammatory reactivity and subsequently risk for AUD.

63 ntial to forge a connection between chemical reactivity and supramolecular material structure.

64 ceived extensive attention due to their high reactivity and toxicity in vitro and in vivo.

65 f diazomethane, these suffer from diminished reactivity and/or correspondingly harsher conditions.

66 We tested the expression, reactivities, and stabilities of 123 single engineered m

67 ain processes: neuronal transmission, immuno-reactivity, and development.

68 We evaluated the magnitude, cross-reactivity, and functionality of NS1-specific IgG antibo

69 ding their structure, mechanism, alternative reactivity, and maturation.

70 a functionalized active site, size-selective reactivity, and multistep activation, all from a single

71 ysiological indices of fear learning, stress reactivity, and stress-induced affective responses.

72 retinoid trafficking, to prevent nonspecific reactivity, and to conserve the 11-cis configuration.

73 ing, "oral challenge or provocation," "cross-reactivity," and "antimicrobial stewardship".

74 d hydrazones is presented whose behavior and reactivity are governed by various types of weak C-H hyd

75 The molecular rules driving TCR cross-reactivity are poorly understood and, consequently, it i

76 The resulting protein function and reactivity are used to install radical precursors for ho

77 to increase its blood flow (cerebrovascular reactivity) are relatively new areas of investigation.

78 was associated with a decrease in mast-cell reactivity as attested by the reduction of mMCP-1/7 in p

79 rest for allergenic proteins with high cross-reactivity as observed in the lipid transfer protein (LT

80 ulness meditation predicts reduced emotional reactivity, as measured by the late positive potential (

81 inhibition also attenuated autonomic stress reactivity, assessed via electrodermal activity, and pro

82 Astrocyte reactivity associated with brain metastases impaired cer

83 e bulky P-substituent gives marked different reactivities at the 2- and 7-positions, allowing the syn

84 vity of benzylic C(sp(3))-H bonds to achieve reactivity at the homobenzylic position can be accomplis

85 Overall, this study introduces a new reactivity-based probe of the ferrous iron-dependent int

86 nd to imines, focusing on the differences in reactivity between allylmagnesium halides and other Grig

87 Our findings support possible cross-reactivity between dengue virus and SARS-CoV-2, which ca

88 ith previous reports of a low allergic cross-reactivity between PCN and later-generation cephalospori

89 Further FLP reactivity between the uranium(IV)-amide, dihydrogen, an

90 the GPhos-supported catalyst exhibits better reactivity both under ambient conditions and at elevated

91 found to have little influence on breath OH reactivity but enhanced dermal OH reactivity significant

92 ood correlation at the outer limits of thiol reactivity but less so for compounds with intermediate r

93 bain and CdCl(2)) demonstrates that cellular reactivity can be boosted by light driven perturbations

94 onal design of photoswitchable systems whose reactivity can be controlled via host-guest interactions

95 ta were acquired during a mild visual stress reactivity challenge.

96 y, a "real-world" application shows that the reactivity changes of subresidue isomers at Phe399 can i

97 This species displays enhanced reactivity compared to its mononuclear counterpart due t

98 m, strong CO(2) adsorption and hydrogenation reactivity could be restored.

99 y differences in their specificity and cross-reactivity dependent on pre-existing immunity.

100 comprehending the impact of individual local reactivity descriptors on the global PES.

101 How do local reactivity descriptors, such as the Fukui function and t

102 ional theory are in excellent agreement with reactivity determined experimentally.

103 ads in recipients who became infected, cross-reactivity did appear to influence early viral evolution

104 table as biological probes due to widespread reactivity, dienone compounds are cytotoxic to apoptosis

105 uch as RNA-binding-protein binding sites and reactivity differences at single-nucleotide variants.

106 ) calculations were performed to explain the reactivity differences between indazole and indole elect

107 Compared to pre-HDTBR, cerebrovascular reactivity during and after HDTBR did not change.

108 Such reactivity, enabled by metal catalysts, additives, or vi

109 powerful tool for predicting mechanochemical reactivity, enabling its widespread adoption to support

110 function as it participates in microvascular reactivity, endothelium interaction with blood constitue

111 We show that T cell reactivity following natural infection and Zostavax vacc

112 at position 16 is necessary to constrain TCR reactivity for InsB(9-23) by both limiting the developme

113 neous and heterogeneous catalysts for tuning reactivity for such a demanding process as C-H functiona

114 This nickel-mediated methodology extends reactivity from previously described air-sensitive diorg

115 No interference/cross-reactivity from Salmonella enteritidis, Enterobacter agg

116 T-cell cross-reactivity generally correlated with allergen sequence h

117 ly in the gas phase, and because of its high reactivity has eluded isolation in the condensed phase.

118 However, such reactivity has proven difficult to reproduce in solution

119 have been unable to directly test the stress-reactivity hypothesis in situ.

120 courage the development of new excited-state reactivities in the field of metallaphotocatalysis that

121 sequent peptide generation, and T-cell cross-reactivity in a BALB/c murine model.

122 as been performed to interrogate itaconate's reactivity in cell lysates, but methods for analyzing ta

123 (ENMs) require a better understanding of ENM reactivity in complex, biologically active systems for c

124 Our data demonstrate that the lack of cross-reactivity in glycan hole antibodies is due to amino aci

125 ate the CO(2)/H(+) effect on cerebrovascular reactivity in mice.

126 clo-oxygenase-1 blockade, including platelet reactivity in response to arachidonic acid (mean differe

127 at allows us to recapitulate photoredox-like reactivity in the absence of light across a wide range o

128 investigation of the 10-membered enediynes' reactivity in the Bergman cyclization are also reported.

129 ecedented example of reductive cycloaddition reactivity in the chemistry of 2-phosphaethynolate.

130 fection, but little is known about CD8 cross-reactivity in the context of HIV-1 vaccination.

131 pair Lewis bases display superior catalytic reactivity in the reaction of isocyanates with alcohols

132 ions, thus demonstrating CO(2)/H(+) vascular reactivity in the RTN is unique.

133 on enzyme catalysis to include a dioxygenase reactivity in which an unactivated alkene is converted t

134 irus (DENV), the role of immunological cross-reactivity in ZIKV and DENV infections has become a grea

135 ion of chemical groups with highly selective reactivity into small molecules or protein modifications

136 avage of the RNA model substrate HPNP, whose reactivity is 30-fold larger with respect to the unstruc

137 The reactivity is broad in scope, enabling the copolymerizat

138 ical processes, and elucidating how chemical reactivity is efficiently controlled within well-defined

139 and chick, the transition from quiescence to reactivity is essential for retinal regeneration, wherea

140 The ability to understand and predict reactivity is essential for the development of new react

141 0-dihydro-9-boraphenanthrene and its diverse reactivity is investigated.

142 We determined the MAb cross-reactivities, localized the epitopes, and measured funct

143 This cross-reactivity may worsen symptoms of a subsequent infection

144 Reactivity measurements at atmospheric pressure with 30

145 C radical dication, thus demonstrating a new reactivity mode for this electrophotocatalyst.

146 that important covalent, i.e., spin pairing, reactivity modes can be missed when only a single spin-p

147 s of this review is to classify the existing reactivity modes of CF(3)CHN(2) and to systematically an

148 A summary is made of the three main reactivity modes, namely, homoenolate chemistry, beta-ke

149 rocesses to alternative recognition-mediated reactivity modes.

150 [19-30 years of age]) investigating emotion reactivity (N studies = 48), and implicit (N studies = 4

151 e intrinsic physical properties and chemical reactivities not previously seen in such systems.

152 The reactivity observed with nonspecially activated unsatura

153 model was used to rationalize the different reactivities of O- and S-substituted heteroallenes.

154 , we demonstrated that the C-H bond cleaving reactivity of 1 can be further enhanced by introducing a

155 an hole epitope in an attempt to broaden the reactivity of a B41-specific nAb, but we recovered only

156 e so-called alpha effect, i.e. the increased reactivity of a nucleophile when the atom adjacent to th

157 hamber occupied by four people, the total OH reactivity of air was quantified, together with multiple

158 ubstantial change in structure and gas phase reactivity of Al(3)O(4)(+) upon Fe-substitution, which i

159 turtles from Florida, we rejected the cross-reactivity of antibodies to other herpesviruses, differe

160 The study revealed differences in the reactivity of antibody reagents to cIPV and sIPV product

161 imal model of reactive astrocytes, where the reactivity of astrocytes can be manipulated as mild (GiD

162 useful information on the high nucleophilic reactivity of benzofuroxan derivatives, which has been r

163 Herein we show that leveraging the reactivity of benzylic C(sp(3))-H bonds to achieve react

164 tion to persist the iterative cycle, but the reactivity of both steps is highly affected by the exist

165 in how the proteinaceous environment control reactivity of Cu with O(2).

166 The properties and stereochemical reactivity of cyclobutadiene, benzene, cyclooctatetraene

167 ibutable to intrinsic differences in surface reactivity of different Au sites in the DFT model.

168 Results, obtained from the reactivity of free sulfhydryl groups and fluorescence an

169 understanding of fundamental organometallic reactivity of gold(III) has revealed unexpected mechanis

170 The three-center halogen bond modulates the reactivity of halonium ions and is hence a useful tool f

171 Overall, the reactivity of HoxEFU observed here suggests that it func

172 ography analyses are applied to evaluate the reactivity of KO(2) in ambient air.

173 plications for an accurate assessment of the reactivity of manganese oxides used as engineered geomed

174 The reactivity of mechanophores (mechanosensitive molecules)

175 ed because of issues associated with the low reactivity of metal fluorides.

176 These results give a new insight into the reactivity of molecules under tension.

177 amidation reactions provide insight into the reactivity of N-acyl-glutarimides in metal-catalyzed and

178 The unique and versatile reactivity of nickel enables the oligomerization of ethy

179 reactive groups is difficult because of high reactivity of organometallic reagents.

180 The reactivity of our system was further probed by photolyzi

181 /Au thin film surfaces affect the nature and reactivity of Pd/Au surface electrochemistry including t

182 oduce a comprehensive methodology to map the reactivity of photochemical systems on surfaces.

183 These findings provide insight into the reactivity of sterically congested aromatic systems and

184 tion is investigated, and differences in the reactivity of tertiary amine substrates are discussed.

185 lectrode are intrinsically linked to surface reactivity of the active material.

186 To determine the structure and reactivity of the species formed by oxidation of these C

187 t of B cell progenitors in bone marrow; poly-reactivity of the VRC26UCA and poor pairing of the VRC26

188 The stepwise reactivity of the zwitterion provides new mechanistic in

189 The reactivity of these end-capped polymers is illustrated h

190 approaches are available for modulating the reactivity of this species.

191 The relative reactivity of various substrates supports the proposed m

192 inity maturation process and potential cross-reactivity of VH3-23/VK1-5 neutralizing Abs, informing p

193 ysical arrangement, rather than the chemical reactivity, of the complexes.

194 rging opportunities for exciting "crossover" reactivity offered by these derivatives of the p-block e

195 Here, we show the importance of astrocytic reactivity on the pathogenesis of AD using GiD, a newly

196 or selections often have significant gaps in reactivity or require synthesis of precursor libraries c

197 ant as atmospheric oxygen in limiting pyrite reactivity over Earth's history.

198 eta-keto sulfones by exploiting differential reactivity pattern of substrates under open-atmosphere a

199 munosorbent assays (ELISAs) revealed several reactivity patterns, including individual adhesin specif

200 alence tautomerism are in line with observed reactivity patterns.

201 chemistry and differs from the conventional reactivity principles employed in the synthesis of polym

202 Using a general reactivity probe, we generated a data set of proteomic c

203 i.d.) reduced alcohol craving during the cue-reactivity procedure.

204 e aromatic unit is dictated by the intrinsic reactivity profile of the method (electrophilic halogena

205 st glycosylations and highlight the distinct reactivity properties of alpha- and beta-glycosyl trifla

206 1 B cell sub-populations with distinct cross-reactivity properties were activated by each immunogen,

207 uneven spin distribution is reflected in the reactivity-reaction with oxygen occurs selectively at a

208 This marked difference in reactivity reflects the ability of Zn to promote a rate-

209 A comprehensive understanding of structure-reactivity relationships is critical to the design and o

210 p between the surface absorption spectra and reactivity remains unexplored.

211 er, the source and clinical relevance of the reactivity remains unknown.

212 IDs), this novel method of activation offers reactivity remarkably greater than that of other reporte

213 ue to its remarkable versatility in terms of reactivity representing a foremost tool in synthesis.

214 Therefore, a variation of precursor reactivity requires the synthesis of different precursor

215 breath OH reactivity but enhanced dermal OH reactivity significantly.

216 termine the role of STAT3-mediated astrocyte reactivity, specifically, in brain metastasis.

217 Reactivity studies in the Suzuki-Miyaura cross-coupling

218 Reactivity studies of 3 corroborate its carbene-like nat

219 Structural and reactivity studies provided a deeper understanding of th

220 Reactivity studies, in combination with quantum chemical

221 l as an algorithmic approach, based on cross-reactivity studies, in patients with a suspicion of BL h

222 ersubclass specificity, and class-wide cross-reactivity, suggesting that some conserved epitopes, inc

223 Cr(0) exhibited a much higher reactivity than Cr(III) in the formation of Cr(VI) by ch

224 These results reveal reactivity that is available to cyclic allenes beyond th

225 use of directing groups, achieving valuable reactivity that traditionally would require multiple che

226 -cell infiltration, proliferation and immune reactivity, thereby contributing to tumour immune evasio

227 The MAbs' reactivities to a panel of class 5 adhesins in enzyme-li

228 to a wild-type 3c3.A strain and very limited reactivity to 3c2.A strains, including the currently cir

229 vailable at all 3 ages were analyzed for IgE reactivity to 8 Phleum pratense (Phl p) allergens (MeDAL

230 strain elicits antibodies that have reduced reactivity to a wild-type 3c3.A strain and very limited

231 Yet cross-reactivity to additional microbes is important to consid

232 allergic rhinitis (LAR) are defined by nasal reactivity to aeroallergens with and without positive sk

233 This study shows that nasal reactivity to aeroallergens with and without positive SP

234 stablish and survive, while dampening immune reactivity to allergens, autoantigens and microbiome det

235 dulation may remove key checks on microglial reactivity to amyloid and tau.

236 DSA-positive AMR patients exhibited greater reactivity to autoantigens compared to DSA-negative (P <

237 ctivity to Rv0134 and an AUC of 0.98 for IgA reactivity to both Rv0629c and Rv2188c.

238 s to specific glycan moieties and found that reactivity to classical CCD epitopes (core beta-1,2-xylo

239 hange in arterialized PCO2 , cerebrovascular reactivity to CO(2) or the hypercapnic ventilatory respo

240 te and compare the predicted mechanochemical reactivity to experimental results.

241 ironment and Sm infection, but not with skin reactivity to extracts or sensitization to their major a

242 BNC210 reduced amygdala reactivity to fearful faces relative to placebo and simi

243 es in H/D exchange rates and analyses of mAb reactivity to homologous LTPs revealed three structural

244 Co-reactivity to more than one nut is frequent, and co-sens

245 ative to placebo, nicotine induced more NAcc reactivity to reward anticipation.

246 a novel D1 agonist (relative to placebo) on reactivity to reward-predicting cues (Pavlovian-to-instr

247 the curve (AUC) of 1.0 was observed for IgA reactivity to Rv0134 and an AUC of 0.98 for IgA reactivi

248 ith good developability properties and cross-reactivity to SARS-CoV-2 mutants provide a strong ration

249 Hyper-reactivity to sensory input is a common and debilitating

250 ry and infection, anticipatory neural-immune reactivity to social threat was likely highly conserved.

251 cts vary with the estrous cycle, and whether reactivity to specific stressors may manifest as drug se

252 hile Shingrix vaccination redirects dominant reactivity to target gE.

253 trajectories and promote a widely different reactivity to the environment.

254 plates in their native form and assayed for reactivity to two types of antibodies, full-length 7S Ig

255 rm as well as long-term repression of T-cell reactivity to unrelated pathogens.

256 Markers of stress reactivity together with spinal/brain opioid receptor ex

257 The Si=C bonds show a distinguished reactivity toward CO(2), depending on the reaction condi

258 photocaged cell-permeable probe showed good reactivity toward purified DUBs, including USP2, UCHL1,

259 n molecular complexes and metal NPs in their reactivity toward sigma-bond activation and functionaliz

260 y elucidate the factors that influence their reactivity toward the electron-poor trichloroacetyl isoc

261 gical perspective: A high level of IgE cross-reactivity towards allergens from the birch homologous g

262 ated with chemical reactions and thus govern reactivity trends and regioselective preferences?

263 ) theory is advanced to explain the observed reactivity trends.

264 This reactivity umpolung enables the formal alpha-allylation

265 scinating small molecules with complementary reactivities under radical, ionic, and metal-catalyzed c

266 tients sera indicated a 50% reduction in IgE-reactivity upon EDTA presence.

267 butor to the observed changes in interfacial reactivity upon illumination.

268 nstrated as a promising method to expand DEL reactivity using standard organic synthesis protocols.

269 were measured, in addition to microvascular reactivity, using laser Doppler imaging with iontophores

270 Results show that reactivity varies widely among PFASs, but reaction rates

271 the allyloxocarbenium system decrease glycal reactivity via negative hyperconjugation as protecting g

272 The protein's IgE reactivity was analyzed in ELISA experiments, and cross-

273 Anti-CNS antibody reactivity was evident in the sera of the MS cohort, and

274 Evoked vascular reactivity was impaired in mice with CAA, which correspo

275 ted that intrinsic cysteine, and not lysine, reactivity was important for activity against HCMV.

276 No significant difference in total OH reactivity was observed for different age groups (teenag

277 its effects on muscle and parvalbumin's IgE-reactivity were analyzed.

278 eceiving placebo, whereas levels of platelet reactivity were similar with adenosine diphosphate and t

279 involved in the prediction of physiological reactivity, whereas some regions previously associated w

280 iron or cobalt complexes to promote radical reactivity which have been devised over the last decades

281 nation underlying the distinct CD8(+) T cell reactivities, which reinforces the concept that peptide

282 eered to further improve their C-H amination reactivity, which demonstrates their evolvability for ab

283 However, there is no evidence of cross-reactivity, which explains this observed co-sensitizatio

284 tural similarity with cyanobacterial Fds and reactivity with a host sulfite reductase suggest that ph

285 ination were isolated and examined for their reactivity with a tertiary carbon radical.

286 was analyzed in ELISA experiments, and cross-reactivity with allergens of other poultry species was a

287 in the native envelope of HSV-1 had reduced reactivity with antibodies in comparison to gB from the

288 rize pathways of T cell activation and cross-reactivity with clozapine metabolites and olanzapine.

289 sive (phenanthroline)Ni(I) species and their reactivity with CO(2), allowing us to address a long-sta

290 nd anti-TNF significantly modulated amygdala reactivity with IFN-alpha acutely enhancing right amygda

291 Absence of cross-reactivity with mammalian species tested in the study co

292 molysis and exhibited hydroalkoxylation-like reactivity with methanol.

293 concentrations to overcome phosphate's poor reactivity with organics in water.

294 tibodies and their binding avidity and cross-reactivity with other alphaviruses increased over time.

295 ies/reaction) and high specificity (no cross-reactivity with other mcr variants).

296 s (83%), but this was primarily due to cross-reactivity with preventive vaccine-induced anti-feline p

297 synthesized and examined for their inherent reactivity with tertiary carbon radicals.

298 fer from poor cell permeability and/or cross-reactivity with the cysteine protease cathepsin B.

299 f serologies is confounded by antibody cross-reactivity with viruses belonging to the same serogroup

300 kinetic barrier, a unique case of two-state reactivity without a change in the net spin multiplicity