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1 utamate terminals, reducing release from the readily releasable pool.
2 the well-known exponential refilling of the readily releasable pool.
3 ng vesicles, presumably corresponding to the readily releasable pool.
4 n of recycling vesicles partitioned into the readily releasable pool.
5 from an increased number of vesicles in the readily releasable pool.
6 the proportion of recycling vesicles in the readily releasable pool.
7 replenishment and increased the size of the readily releasable pool.
8 tant- and fast-releasing subdivisions of the readily releasable pool.
9 ion, a putative regulator of the presynaptic Readily Releasable Pool.
10 A53T inhibited vesicle replenishment to the readily releasable pool.
11 ndown kinetics upon intense activity and the readily releasable pool.
12 also inhibited vesicle replenishment to the readily releasable pool.
13 is, and inhibits vesicle mobilization to the readily releasable pool.
14 may convert docked synaptic vesicles into a readily releasable pool.
15 e probability of release and the size of the readily releasable pool.
16 depleting the reserve pool and enhancing the readily releasable pool.
17 ing but is required for the full size of the readily releasable pool.
18 n overshoot pool approximately 1.8 times the readily releasable pool.
19 vesicle release preferentially involves the readily releasable pool.
20 ing residual evoked release and rescuing the readily-releasable pool.
21 rs alter the equilibrium between reserve and readily releasable pools.
22 ization from the reserve pool to the docked (readily releasable) pool.
23 g, this substitution reduced the size of the readily releasable pool, a novel function for Cpx at mam
24 maturely, and redirecting them to refill the readily releasable pool after relaxation of the calcium
26 of simultaneously released vesicles) in the readily releasable pool and their replenishment time con
27 hange was associated with a reduction in the readily releasable pool and vesicle recycling which impa
28 pid endocytosis, vesicle mobilization to the readily releasable pool, and recovery of synaptic depres
29 t not CA1 synaptosomes by (1) increasing the readily releasable pool as tested by hypertonic sucrose;
31 that phorbol esters increase the size of the readily releasable pool at glutamatergic hippocampal syn
32 , and that Epac2 is required to maintain the readily releasable pool at MF synapses in the hippocampu
33 apse showed slower replenishment rate of the readily releasable pool at relatively high but physiolog
34 neurons in culture, the size of the autaptic readily releasable pool before and after stimulation of
35 t synaptic release and increased size of the readily releasable pool but decreased sensitivity for th
36 nhanced in size to a greater extent than the readily releasable pool but is eliminated upon expressio
37 not caused by an increase in the size of the readily releasable pool but is instead associated with a
38 short-duration train, which interrogates the readily releasable pool, but depleted release elicited b
39 onversion of docked synaptic vesicles into a readily releasable pool by activating SNAREs for efficie
40 ogether, in this system replenishment of the readily releasable pool by the reserve vesicles was stri
41 ute places vesicles selectively into a small readily releasable pool comprising about 20% of vesicles
42 release probability, and (2) the size of the readily releasable pool exclusively at excitatory synaps
43 sites with low release probability, a large readily releasable pool, fast presynaptic calcium cleara
44 es exocytosis of synaptic vesicles after the readily releasable pool has either been physiologically
48 tter-containing synaptic vesicles (SVs), the readily releasable pool, is available for fast Ca(2+)-in
49 e pulse could be entirely accounted for by a readily releasable pool of approximately 200 vesicles.
51 alpha-methyl-p-tyrosine, which depletes the readily releasable pool of dopamine, cocaine was still c
52 that membrane-attached vesicles comprise the readily releasable pool of fusion-competent vesicles and
56 tion arising from an increase in size of the readily releasable pool of insulin SGs and enhanced SG p
57 , one holds that the first phase is due to a readily releasable pool of insulin-containing granules.
58 NEM induced a dose-dependent increase in the readily releasable pool of neurotransmitters but by itse
60 Since exocytosed vesicles are drawn from a readily releasable pool of packaged transmitter, enhance
61 tool with which to probe the function of the readily releasable pool of presynaptic vesicles at CNS s
63 his small GTPase in reducing the size of the readily releasable pool of SVs and in channeling retriev
66 , we directly measured the refilling of this readily releasable pool of synaptic vesicles after Ca(2+
67 al-GTPase signaling in the modulation of the readily releasable pool of synaptic vesicles and suggest
68 ethod can currently detect exocytosis of the readily releasable pool of synaptic vesicles at a hippoc
69 ering of Ca(2+) channels and the size of the readily releasable pool of synaptic vesicles at active z
70 iming and docking and their loss reduces the readily releasable pool of synaptic vesicles by up to 75
71 to be due to enhancement of the size of the readily releasable pool of synaptic vesicles docked at t
72 ontrolling the homeostatic modulation of the readily releasable pool of synaptic vesicles following i
73 e study revealed that pregabalin reduces the readily releasable pool of synaptic vesicles in an N-met
74 f donor and acceptor vesicles, mimicking the readily releasable pool of synaptic vesicles prior to an
75 es in the size and replenishment rate of the readily releasable pool of synaptic vesicles without cha
76 ium-dependent enhancement of the size of the readily releasable pool of synaptic vesicles, and a resu
77 the total extent of evoked release, size of readily releasable pool of synaptic vesicles, and releas
78 ssed isoforms, SV2A and SV2B, have a reduced readily releasable pool of synaptic vesicles, indicating
79 superfused synaptosomes, we have studied the readily releasable pool of synaptic vesicles, measured a
81 zed mutant of synaptotagmin 1 suppressed the readily releasable pool of synaptic vesicles, whereas wi
94 p) before hearing onset, and by an increased readily releasable pool of vesicles (RRP) thereafter.
95 nses are believed to mobilize sequentially a readily releasable pool of vesicles (RRP) underneath the
98 inal) prevented decreases in the size of the readily releasable pool of vesicles and in the percentag
99 though effects of phorbol esters both on the readily releasable pool of vesicles and on presynaptic c
100 Munc18-1 which results in a decrease in the readily releasable pool of vesicles at a synapse, sugges
101 However, with adaptation, depletion of the readily releasable pool of vesicles diminishes quantal c
102 pment, critical for the proper maturation of readily releasable pool of vesicles during early develop
103 asynchronous release completely empties the readily releasable pool of vesicles during sustained ele
104 ta produce PTP by increasing the size of the readily releasable pool of vesicles evoked by high-frequ
105 tained trains of activity suggested that the readily releasable pool of vesicles is reduced in Epac2(
107 various durations show that the size of the readily releasable pool of vesicles nearly doubles with
108 of RIM1alpha causes a large reduction in the readily releasable pool of vesicles, alters short-term p
109 not due to an alteration of the size of the readily releasable pool of vesicles, but are attributabl
110 nts, enhanced synaptic depression, a smaller readily releasable pool of vesicles, delayed endocytosis
111 anges in mini frequency, mini amplitude, the readily releasable pool of vesicles, or the apparent Ca(
112 , region I mutations reduced the size of the readily releasable pool of vesicles, whereas the region
117 restricts release and limits the size of the readily-releasable pool of synaptic vesicles at the acti
118 ted the size, but not the properties, of the readily-releasable pool of vesicles at inhibitory synaps
119 the reserve pool first and subsequently the readily releasable pool over a period of several minutes
120 osis facilitated vesicle mobilization to the readily releasable pool, probably by clearing fused vesi
121 and of evoked-release amplitudes (indicating readily-releasable pool refilling) occurred within appro
122 e pool size and the rate of refilling of the readily releasable pool remain unaltered by latrunculin
123 esicle mobilization and replenishment of the readily releasable pool require GTP and Ca2+ but do not
124 cium dependence of the effective size of the readily releasable pool (RRP) also contributes to the ca
125 This change applies to the release of both a readily releasable pool (RRP) and a slower secondary poo
126 es, the physiologically measured size of the readily releasable pool (RRP) and the release probabilit
127 rphological and functional properties of the readily releasable pool (RRP) and the reserve pool of sy
130 hment of docked synaptic vesicles within the readily releasable pool (RRP) from synaptic vesicle clus
132 trations of the Ca(2+)-buffer EGTA created a readily releasable pool (RRP) of 87 synaptic vesicles (S
133 IH resulted in a significant increase in the readily releasable pool (RRP) of secretory granules, and
134 retardation of the rate of refilling of the readily releasable pool (RRP) of secretory granules.
135 This Ca(2+)-evoked release occurs from a readily releasable pool (RRP) of SVs docked to the plasm
137 During intense presynaptic activity, the readily releasable pool (RRP) of synaptic vesicles empti
138 paired-pulse stimuli designed to deplete the readily releasable pool (RRP) of synaptic vesicles in ha
139 sociated with an increase in the size of the readily releasable pool (RRP) of synaptic vesicles, cons
140 that exceed the rate of replenishment of the readily releasable pool (RRP) of synaptic vesicles, depr
141 tonic solutions that measure the size of the readily releasable pool (RRP) of synaptic vesicles.
143 nd -2 suggested that complexin maintains the readily releasable pool (RRP) of vesicles and clamps spo
146 enerated uIPSCs in granule cells to evaluate readily releasable pool (RRP) size and resupply rate of
147 s (with potency D166Y > V48F) led to reduced readily releasable pool (RRP) size, due to increased spo
148 r, we show that another presynaptic feature, readily releasable pool (RRP) size, is tonotopically dis
150 ositional fate of vesicles endocytosed after readily releasable pool (RRP) stimulation in rat hippoca
151 Although it takes several seconds for the readily releasable pool (RRP) to refill during periods o
152 pid endocytosis recycles vesicles within the readily releasable pool (RRP) via a kiss-and-run mechani
153 e from nascent synapses without a functional readily releasable pool (RRP) was unresponsive to PMA ap
154 Tomo1 facilitates release efficacy from the Readily Releasable Pool (RRP), and regulates SV distribu
155 s from 30-month-old mice showed no change in readily releasable pool (RRP), but a slower vesicle repl
165 ipine, mainly control the fast fusion of the readily releasable pool (RRP); that is, they encode the
166 increase in release probability (Pr ) and/or readily-releasable pool (RRP) in many synapses, but the
167 increase in release probability (Pr ) and/or readily-releasable pool (RRP) in many synapses, but the
168 increase in release probability (Pr ) and/or readily-releasable pool (RRP) of synaptic vesicles (SVs)
169 lcium influx, and diminishes the size of the readily-releasable pool (RRP) of synaptic vesicles, cons
170 ctively, but does not change the size of the readily-releasable pool (RRP) of vesicles as measured by
171 stimulation revealed that as P declines, the readily releasable pool size (N) increases so that the n
173 ds to tighter release coupling, an increased readily releasable pool size and more release sites ther
174 dose-response fitting of Stx1 levels against readily releasable pool size and vesicular release proba
175 ndocytosis overshoot, but did not affect the readily releasable pool size, Ca(2+) influx, or exocytos
176 erely impaired, as demonstrated by a smaller readily releasable pool size, slower refilling rate of p
177 ersely, CR-expressing synapses had a smaller readily releasable pool size, which was countered by hig
180 lized at synaptic ribbons participate in the readily releasable pool that is tapped rapidly during de
181 We tested this by selectively labeling the "readily releasable" pool, those vesicles released first
182 core complexes, to study the relation of the readily releasable pool to core complex assembly in syna
183 , we find Tomo1 actions to extend beyond the Readily Releasable Pool to mediate the Total Recycling P
184 sence of Doc2b, release was shifted from the readily releasable pool to the subsequent sustained comp
185 ve to [Ca2+]i than the previously described "readily releasable pool." Upon activation of PKC, this "
186 les released is regulated by the size of the readily-releasable pool, upstream of vesicle release pro
187 anipulation of the number of vesicles in the readily releasable pool using phorbol ester treatment su
190 nicotine-induced increase in the size of the readily releasable pool was blocked by alphaBgTx and by