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1 ally significant catalytic process (Beckmann rearrangement).
2 se of the difficulty of inducing the initial rearrangement.
3 intermediate generated during [3,3]-acyloxy rearrangement.
4 ate group participation during [3,3]-acyloxy rearrangement.
5 ydropiperidines in a highly stereocontrolled rearrangement.
6 ha genes, and its deletion impaired the Tcra rearrangement.
7 trectinib, regardless of tumour type or gene rearrangement.
8 ufficient to predict the onset of rapid cell rearrangement.
9 its occupation by competing Ca(2+) slows the rearrangement.
10 te myelination depends on actin cytoskeleton rearrangement.
11 uently developed based on a key Wittig-Still rearrangement.
12 evel copy-number gains and frequent inverted rearrangements.
13 host interactions such as water-induced bond rearrangements.
14 to deformations, and fast internal molecular rearrangements.
15 ukemias, notably those with KMT2A (MLL) gene rearrangements.
16 transient or persistent mutations and genome rearrangements.
17 extraordinary carbon backbone and side-chain rearrangements.
18 ice using acquired mutations and chromosomal rearrangements.
19 R3 promoter and elicits occlusive nucleosome rearrangements.
20 lterations that co-occurred with ERG genomic rearrangements.
21 EJ and ATM kinase inhibition influence these rearrangements.
22 (including prophages) combined with genomic rearrangements.
23 ocarcinoma with and without FGFR2 fusions or rearrangements.
24 e stable length or collapse to initiate cell rearrangements.
25 hion and shows typical TRGV9- and TRDV2-like rearrangements.
26 ns within a polypeptide chain and/or subunit rearrangements.
27 des in surface TCRs and carry Trbv31-DJbeta2 rearrangements.
28 , a breakage-fusion-bridge and other complex rearrangements.
29 72 adults with AML and recurrent 11q23/KMT2A rearrangements, 141 of whom had outcome data available.
30 through a three-step cascade involving Cope rearrangement, 6-exo-trig cyclization, and a final elect
31 I 26.5-45.4]) patients with FGFR2 fusions or rearrangements achieved an objective response (three com
32 or the characterization of the transcriptome rearrangements affecting disease progression independent
33 tion and subsequently catalyze covalent bond rearrangement, affording selective assembly of the oligo
35 HsZnT8 subunit undergoes a large structural rearrangement, allowing for alternating access to the pr
36 chromatin interaction datasets, we identify rearrangements altering the regulatory landscape of gene
37 While the reconstructed sequence of genome rearrangements among the protein-coding and ribosomal RN
38 of the central problems presented in genome rearrangement analysis since finding the most likely tru
39 ccurs through a BvnE-controlled semi-pinacol rearrangement and a subsequent spontaneous intramolecula
40 imary mechanism that accelerates genomic DNA rearrangement and amplification into ecDNA and enables r
42 ents; however, these can promote local lipid rearrangement and can cause fluctuations in the oligomer
43 ustering by Gal-9 may influence cytoskeleton rearrangement and coclustering of CD3, which likely impa
44 dynamically favored through an electrophilic rearrangement and concomitant 1,9-aryl migration without
45 anscription, these complexes undergo dynamic rearrangement and disassembly as Pol II moves away from
47 on Pten-NOLC1 originated from a chr10 genome rearrangement and identified through a transcriptome seq
48 oximal V(H)s, where additional CBEs activate rearrangement and impede scanning any further upstream(5
49 , the cascade continues with a Dowd-Beckwith rearrangement and leads to the formation of the 13(14 ->
50 natural specificities and a repertoire, VDJ rearrangements and CDRH3 characteristics similar to thos
52 by G(s)-coupled GPCRs, inducing cytoskeletal rearrangements and formation of filopodia-like structure
57 esponse that involves dynamic receptor dimer rearrangements and that is kinetically embedded between
58 trifurcating organic reaction, a carbocation rearrangement, and solvent-dependent Pummerer-like react
59 on transfer (SET) to this system initiates a rearrangement, and the catalytic cycle is completed by r
60 including lipid-protein interactions, domain rearrangement, and water-mediated diffusion mechanisms.
61 orchestrated nuclear cleavages, cytoskeletal rearrangements, and directed membrane growth lead to the
65 t for molecular electronics but because such rearrangements are low energy, measuring their rapid dyn
70 ation, accompanied by substantial structural rearrangements at the cytoplasmic intersubunit interface
72 osed as minimization of the number of genome rearrangements between extant and ancestral genomes.
73 r, have provided a picture of how structural rearrangements between transmembrane helices control lig
74 nes and malononitrile, not only initiate the rearrangement but also are responsible for the nature of
75 on ancestor and share the same initial V(D)J rearrangement, but their B cell receptor (BCR) sequence
76 gle nucleotide variants to large chromosomal rearrangements, but the extent of structural variation i
77 enzyme and promotes CSR and aberrant genomic rearrangements by suppressing the insertional DNA repair
78 enium hydride-mediated isomerization/Claisen rearrangement cascade and a ring-closing metathesis that
79 mes of 1,097 patients without an 11q23/KMT2A rearrangement categorized according to the 2017 European
80 ic and non-allelic mutations and chromosomal rearrangements characteristic of nuclease-dependent proc
81 tes whose electrophile-induced 1,2-metallate rearrangement chemistry enables a broad range of C-C bon
84 are an unanticipated major source of somatic rearrangements, contributing to oncogenic remodeling thr
86 hylogeny, direct inference of phylogeny from rearrangement data in MLGO resulted in a highly discorda
87 T cells using Vdelta1(+) and Vdelta3(+) TRD rearrangements did not significantly expand after birth.
89 ial genomes are marked by high rates of gene rearrangement, duplications of the control region and tR
91 d whether the cofactor undergoes significant rearrangement during turnover; resolution of these issue
94 sight about both strain rate and constituent rearrangement dynamics in the sample at earlier times.
97 ects cells away from the niche, while random rearrangements enable cells away from the niche to be fa
98 that form an aromatic pathway whose dynamic rearrangements enable H(+) movement outside the Cl(-) po
99 lineage, although frequent recombination and rearrangement events between them have led to a complex
100 n of U2 to the spliceosome, and identify RNP rearrangements facilitated by PRP5 that are required for
101 Additionally, we unravel a unique ligand rearrangement for these classes of anionic mesoionic car
102 the entire cleavage module undergo extensive rearrangements for activation, triggered through the rec
105 with a higher quality target elevates Vbeta rearrangement frequency before feedback inhibition, dram
106 d interpreting clinically relevant rare gene rearrangements from next-generation sequencing data.
107 etic system that generates gross chromosomal rearrangements (GCRs) mediated by foldback inversions co
109 ytotoxic lesions that can lead to chromosome rearrangements, genomic instability and cell death.
111 tudy shows that patients with an 11q23/KMT2A rearrangement have distinct mutational patterns and outc
112 th 1,3-diketones, easily undergo the Curtius rearrangement in boiling tBuOH to give Boc-protected alp
113 ila germband predict the onset of rapid cell rearrangement in both wild-type and snail twist mutant e
114 ays for melanoidin formation via the Amadori rearrangement in contrast to the reaction from Glc/Ala.
117 ubstituent X on the extent of the structural rearrangement in the process XS -> XS(-) cannot be expla
119 These analyses identified conformational rearrangements in beta2R-Y199(5.38)A that propagated fro
122 from T-cell receptor and immunoglobulin gene rearrangements in context of lymphoproliferative disorde
123 powerful tool for investigating large-scale rearrangements in genome structure upon cell differentia
124 that XLF-dependent C-NHEJ promotes deletion rearrangements in human cells and that cell type-specifi
125 lisation could not anticipate the effects of rearrangements in plant-frugivore communities following
126 Although AUX1 is necessary for full actin rearrangements in response to auxin, cytoplasmic auxin (
127 lix 6 and ultimately inducing conformational rearrangements in the GB2 transmembrane domain via a lev
128 ein correlation profiling to map IFN-induced rearrangements in the human protein-protein interaction
132 a6 linker that likely mediate conformational rearrangements in the protein and cognate rRNA upon inte
133 orm non-B-form DNA induced gross chromosomal rearrangements in yeast and displayed high indel frequen
135 ussed, such as "motif extensions" and "motif rearrangements", including with concomitant extension of
136 Clastogen exposure can result in chromosomal rearrangements, including large deletions and inversions
137 ree RNA highlight the significant structural rearrangements induced by capsid proteins and invite the
138 ubtelomeric tandem repeats; and a variety of rearrangements initiated through breaks in interstitial
139 anoparticles which, in turn, allow for their rearrangement into crystalline domains via solid-state t
140 ative analysis revealed extensive structural rearrangements, introgressions from wild relatives and d
141 old catalyzes an unprecedented benzilic acid rearrangement involving migration of a carboxylate group
144 L) with mixed lineage leukemia 1 (MLL1) gene rearrangement is characterized by increased expression o
146 The mechanism of the organocatalytic Cope rearrangement is elucidated through a combined computati
147 r evolves predominantly via the Stevens type rearrangement leading to an [n + 1] ring expansion of th
148 GAPDH and CD4 genes, that caused a deletion rearrangement leading to CD4 expression from the GAPDH p
151 or fast desensitization and that substantial rearrangements likely correspond to stable desensitized
152 oncurrently, p53 loss instigated chromosomal rearrangements linked to LINE sequences and also provoke
153 through different processes, including gene rearrangements, local nucleotide changes, and the transp
154 s and if left unrepaired can lead to genomic rearrangement, loss of genetic information, and eventual
155 to the fusion of discrete TADs, and complex rearrangements markedly change chromatin folding maps in
156 rrelating energetics data with the molecular rearrangements measured during confinement, we find that
157 hese data suggest that sigma1 conformational rearrangements mediate the efficiency of reovirus host c
158 s accomplished efficiently by employing ring-rearrangement metathesis and ring-closing metathesis as
159 ides, [3 + 2]-cycloaddition, 1,3-sigmatropic rearrangement, Michael addition, and Pictet-Spengler rea
160 This technique not only integrates a naive rearrangement model with a phylogenetic model for BCR se
161 These outcomes indicate that conformational rearrangements must occur in the N terminus of FepA duri
163 ailing a gold(I)-catalyzed propargyl Claisen rearrangement/Nazarov cyclization, a [4+2] cycloaddition
166 They demonstrate that Vbeta-to-DbetaJbeta rearrangement occurs stochastically on two competing Tcr
167 ron oxidation, ring-contractive 1,2-metalate rearrangement occurs to give a cyclobutyl boronic ester.
169 his mode of binding induces allosterically a rearrangement of a noncanonical toggle switch and the op
170 ne A that likely originates from a 1,2-alkyl rearrangement of a protonated 3,3'-spiroindolenine was i
172 yclic carbenes (NHCs) catalyzing aza-Claisen rearrangement of alpha,beta-unsaturated enals with cycli
173 sotope effects (KIEs) for the di-pai-methane rearrangement of benzobarrelene fit with statistical exp
174 findings support a hypothesis of an overall rearrangement of brain connections during human evolutio
177 leading to the discovery of an Amadori-type rearrangement of dopegal in the reaction with several am
178 and TM6b more broadly, help trigger the bulk rearrangement of DraNramp to the inward-open state upon
179 on proceeds via a reductive iodonium Claisen rearrangement of in situ-generated beta-pyridinium silyl
180 approach involves the Fe(II)/Au(I)-catalyzed rearrangement of key 4-propargylisoxazole building block
182 osynthetic routes can now be designed by the rearrangement of nature's unlimited number of enzymes an
183 e the phenomenon does not rely on a physical rearrangement of nuclear positions, material constraints
184 whether the mechanism of the degenerate Cope rearrangement of semibullvalene can be affected by the p
185 fluxes can be inferred from a characteristic rearrangement of stable isotope tracers (e.g., 13C or 15
186 on of ultrasound and chilling contributed to rearrangement of starch molecules, causing a decrease in
187 in, we describe a gold-catalyzed sigmatropic rearrangement of sulfonium and selenium ylides (39 examp
188 , a system of inducible in vivo deletion and rearrangement of synthetic yeast chromosomes, diversifyi
189 slation initiation, AUG recognition triggers rearrangement of the 48S preinitiation complex (PIC) fro
192 location pathway via the XIP, resulting in a rearrangement of the Ca(2+)-binding transport site in th
193 e boronate complexes undergo the desired 1,2-rearrangement of the carbon-based group with complete re
195 agment subsequently mediates a stepwise Cope rearrangement of the doubly dearomatized intermediate to
197 is molecularly characterized by chromosomal rearrangement of the NUT gene to another gene, most comm
198 that monoubiquitination triggers a complete rearrangement of the open, trough-like ID structure thro
199 is monometallic and proceeds via dearomative rearrangement of the phenethylcopper nucleophile to a Cp
203 tants show that ceftazidime acylation causes rearrangement of three loops; the Omega, 240, and 270 lo
207 odel of the genome, we study the large-scale rearrangements of chromatin that happen at different sta
208 Changes in growth cone morphology require rearrangements of cytoskeletal networks, and changes in
209 Changes in growth cone morphology require rearrangements of cytoskeletal networks, but the roles o
210 Reported here are novel formic-acid-mediated rearrangements of dearomatized acylphloroglucinols to ac
211 ructures of tetrameric PfISN1 reveal complex rearrangements of domain organization tightly associated
213 ody mutation trajectories mediate long-range rearrangements of framework (FW) and complementarity det
214 ll lymphoma, high-grade B-cell lymphoma with rearrangements of MYC and either BCL2, BCL6, or both (do
215 of density functional theory calculations on rearrangements of potential biosynthetic precursors to t
216 -box helicase proteins perform ATP-dependent rearrangements of structured RNAs throughout RNA biology
221 y dynamic structural and functional seasonal rearrangements of the photosynthetic apparatus occur.
222 al analyses, we have explored the structural rearrangements of the respiratory chain in human cell li
224 arily public clones, characterized by simple rearrangements of Vgamma9 and Vdelta2 chains with low ju
226 main disruptions can result from chromosomal rearrangements or perturbation of architectural factors.
228 hree cohorts: patients with FGFR2 fusions or rearrangements, patients with other FGF/FGFR alterations
231 go robust D-to-J(H) but little V(H)-to-DJ(H) rearrangements, presumably owing to lack of locus contra
232 enation using a novel tandem acylation/[3,3]-rearrangement process and the reductive 1,2-oxazine ring
237 we report on the limitations of sigmatropic rearrangement reactions of aryl allyl anilines, which de
238 different mechanisms are operative in these rearrangement reactions, with the pathway depending on t
241 It is highly probable that circle-derived rearrangements represent an ongoing mutagenic process.
242 le conformations revealed the intramolecular rearrangements required for alternating access of the me
244 systems could facilitate the conformational rearrangements required to create hierarchical structure
250 s group because of their tendency to undergo rearrangement, sometimes forming bridged ions, as well a
251 effect experiments demonstrate that the Cope rearrangement step, rather than iminium formation, is ra
252 ly of targets based on an abiotic annulation/rearrangement strategy resulting in a 10-step total synt
255 t, a new variation of the anionic Fries-type rearrangement, takes place when nitriles, imines, or alk
256 nd when bound to IP6 revealed an active-site rearrangement that allows for ATP binding and catalysis.
259 t control mechanism for NK cell cytoskeletal rearrangement that is differentially regulated by glucoc
260 a of individual oligomers suggest structural rearrangement that is necessary for oligomers with an an
261 ytic mechanism, including a major structural rearrangement that primes the Cys-122-Cys-66 disulfide f
262 chanical communication is sufficient for the rearrangements that implement epithelial morphogenesis.
263 et of recurrent gliomas carries MGMT genomic rearrangements that lead to MGMT overexpression, indepen
264 characterized by massive, clustered genomic rearrangements that occurs in cancer and other diseases.
265 actions, and allowing us to infer structural rearrangements that permit certain sequence variants to
266 onal changes, including high-energy backbone rearrangements, that cooperatively organized the catalyt
267 n genomic architectures are caused by genome rearrangements, this problem is often posed as minimizat
268 ation and chromothripsis, complex chromosome rearrangements thought to be a major driving force in ca
269 ng catalytic, enantioselective carbocationic rearrangements through the intermediacy of alkyl iodanes
270 structures reveals concerted conformational rearrangements through which the HA mediates membrane fu
272 trile imine 38 is predicted to undergo a new rearrangement to cyanopyridine N-imide 40 with an activa
273 d subsequently undergoes complete structural rearrangement to drive fusion of viral and cellular memb
274 ddition product with Rh(2) (OAc)(4) caused a rearrangement to occur to give a 2-(1H-indol-3-yl)-2-eno
275 equence include a DMAP-mediated O- to C-acyl rearrangement to unite the side chains with the tetramic
276 ent carbocycles and enables abiotic skeletal rearrangements to additional underlying architectures.
277 equent in patients with specific 11q23/KMT2A rearrangements to assess their associations with outcome
278 from cycloaddition reactions and sigmatropic rearrangements to C-H functionalizations, thus allowing
279 complex, Set1 undergoes multiple structural rearrangements to cement interactions with the nucleosom
281 al viral capsids must undergo conformational rearrangements to coordinate essential processes during
282 is therefore not competitive with the known rearrangements to phenyldiazirines, ring expansion to di
283 dergo reversible solid-state inter-molecular rearrangements to produce dinuclear [Cu-Br.(alkene)](2)
284 Caller identifies both heavy and light chain rearrangements to provide additional information on thei
285 and the PDEgamma subunits, driving extensive rearrangements to relieve all inhibitory constraints on
286 , azo coupling resulted in a ring-degenerate rearrangement toward a 2-aryl-4-azotriazapentalene, whic
288 t lowers the free-energy barrier of the Cope rearrangement via an associative transition state that i
292 methylation reactions: a cyclopropylcarbinyl rearrangement was used to trap the substrate radical and
294 responsible for a lumirubin-like structural rearrangement, was thoroughly investigated by liquid chr
298 re B-cell neoplasm initially driven by CCND1 rearrangement with 2 molecular subtypes, conventional MC
299 gh-throughput sequencing techniques, complex rearrangements with multiple breakpoints are often diffi