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1 expression system, whereas others have been recalcitrant.
2 pproximately 1.5-2 d), and carbamazepine was recalcitrant.
3 uorotelomer sulfonic acids (FTSs), were more recalcitrant.
4 ly in forests where litter inputs are highly recalcitrant.
5 lignin that is inherently heterogeneous and recalcitrant.
8 synonymous CGU codons, but the remaining 13 "recalcitrant" AGRs required diversification to identify
9 om temperature decarboxylative allylation of recalcitrant alpha-amino and phenylacetic allyl esters.
10 heir chemical nature CNTs are expected to be recalcitrant and biotransform only at very slow rates.
11 eutic strategies for patients carrying these recalcitrant and complex BCR-ABL1 mutant proteins while
12 nation and reviewed reports of resolution of recalcitrant and disseminated warts after vaccination.
13 e characterized by the presence of lignin, a recalcitrant and hydrophobic polymer that provides mecha
15 hways underscores why fucoidans are probably recalcitrant and more slowly degraded, since only highly
17 omer and perfluorinated compounds, including recalcitrant and toxic compounds such as perfluorooctano
18 logies to treat one of the most troublesome, recalcitrant and ubiquitous classes of environmental con
19 pounds (PFCs) which comprise one of the most recalcitrant and widely distributed classes of toxic pol
20 tem was determined from the degradation of a recalcitrant azo dye and hydroxyl radical (HO.) producti
25 t chitosan can be used to effectively combat recalcitrant bladder infections without causing lasting
29 ount of fast cycling C but a lower amount of recalcitrant C compounds) and normalized CO2-C release i
30 ng-term (>=5 years) warming reduced the soil recalcitrant C pool by 14%, short-term warming had no si
31 warming stimulates microbial utilization of recalcitrant C pools, possibly exacerbating long-term cl
32 atios of labile C to SOC and lower ratios of recalcitrant C to SOC in bamboo soils compared with ceda
34 microbial C and N, soil acid-hydrolysable C, recalcitrant C, and soluble organic C of badland soils.
35 re (36% increase), but a greater increase of recalcitrant C-degrading enzymes in the hyphosphere (118
36 to catalyze reactions with some of the most recalcitrant C-H bonds found in nature as quantified by
37 ed that evolutionary trade-offs would enable recalcitrant C-using taxa to respond more positively to
39 nited States in 2018 and is the epitome of a recalcitrant cancer driven by a pharmacologically intrac
41 incidence that is classified by the NCI as a recalcitrant cancer, i.e., a cancer with poor prognosis,
48 ing diets containing low protein quantities, recalcitrant carbohydrate sources, and plant defensive c
49 ell wall-degrading enzymes to a diversity of recalcitrant carbohydrates under a wide range of environ
52 ghts into the structure and functionality of recalcitrant carbon in soil and its implications for foo
55 ly may be a contributing factor to seemingly recalcitrant cases, inability to wean off immunomodulato
63 n of bacteria that contribute to chronic and recalcitrant clinical infections such as cystic fibrosis
65 ssary for utilization of cellulose, a major, recalcitrant component of the plant cell wall; however,
67 oduct, the diclofenac (DCF), recognized as a recalcitrant compound for conventional water treatments
68 few researchers have studied how labile and recalcitrant compounds interact to influence decompositi
70 hlor) results in the selective enrichment of recalcitrant congeners while other, less persistent comp
71 ore to the exposure (i) to more hydrophobic, recalcitrant congeners, and (ii) of adults than children
72 nation arise from historical episodes, where recalcitrant contaminants have resided in the environmen
73 highly correlated with the concentrations of recalcitrant contaminants such as sucralose, sulfamethox
74 ,1-TCA) and trichloroethene (TCE) are common recalcitrant contaminants that coexist in groundwater.
81 tastatic breast cancer (MBC) is an extremely recalcitrant disease capable of bypassing current target
82 ic ductal adenocarcinoma (PDAC) is a therapy recalcitrant disease characterized by the aberrations in
83 ognostic biomarkers in osteosarcoma, a rare, recalcitrant disease for which treatment standards have
89 properties for the aliphatic halogenation of recalcitrant, electron-deficient, and strained substrate
91 This strategy was validated using previously recalcitrant Fab-antigen complexes where introduction of
97 ils are limited to larval stages (Orsten) or recalcitrant fragmentary remains (SCFs) restricting thei
101 ontaminated soils at 420 degrees C converted recalcitrant heavy hydrocarbons into "char" (a carbonace
103 hallenge to the treatment of therapeutically recalcitrant HER2-positive breast cancers (HER2+ BCs).
104 s case series, 3 patients with biopsy-proven recalcitrant HHD were evaluated in the outpatient dermat
107 ents, the tyrosine-like component was fairly recalcitrant in irradiation and oxidation processes.
108 ticonvulsant pharmaceutical carbamazepine is recalcitrant in many environmental niches and thus poses
109 using disproportionate impact) or to target 'recalcitrants' (individuals avoiding standard control me
110 ing recognition of their role in chronic and recalcitrant infections, the mechanisms that induce pers
114 oid drops to less than 2 drops daily, and/or recalcitrant inflammation necessitating corticosteroid-s
116 descriptors may be used to identify the more recalcitrant isomers, thus allowing prioritization in th
117 cacy of rescue therapy with IL-1 blockade in recalcitrant KD, and we identify that regulation of calc
118 aster) but induced no adverse effects in the recalcitrant lepidopteran pest Helicoverpa armigera.
120 enzymes with high catalytic activity against recalcitrant lignocellulosic material are being explored
121 oody biomass is locked up in the complex and recalcitrant lignocellulosic plant cell wall, making it
122 physical fossils in the sedimentary record, recalcitrant lipid biomarkers are used to unravel microb
123 onged invasion by an exotic plant that input recalcitrant litter (Japanese knotweed, Polygonum cuspid
125 pecies, Polygonum cuspidatum, which produces recalcitrant litter, and Pueraria lobata, which produces
126 mediately affected the mass loss of the more recalcitrant litter, but affected the more labile litter
130 by which R. albus 8 employs to degrade these recalcitrant materials are, however, not clearly underst
132 undance and kbio values for some of the most recalcitrant micropollutants (i.e., diclofenac and targe
134 e new citrate niche, while also suggesting a recalcitrant mismatch between E. coli physiology and gro
138 s aeruginosa is a significant contributor to recalcitrant multidrug-resistant infections, especially
139 pacX mutations suppress PacC processing recalcitrant mutations, in part, through derepressed Pac
142 ion has also been described in patients with recalcitrant nasal polyps, suggesting a link to persiste
144 oil-to-methane conversion is limited by the recalcitrant nature of oil sands bitumen, not the microb
147 e industrial chemicals is exacerbated by the recalcitrant network of lignin, cellulose and hemicellul
149 b can be an effective treatment modality for recalcitrant noninfectious scleritis and, in some, can r
150 lular bacteria, evolved to dominate decay of recalcitrant, nutrient poor substrates such as leaf litt
151 ynamics of BC and to predict the response of recalcitrant OC export to changing environmental conditi
153 ed CRBN-recruiting dTAG molecules to degrade recalcitrant oncogenes, supports combination degrader st
155 y increased stocks of soil total, labile and recalcitrant organic C and N (SLOC, SLON, SROC, and SRON
156 s a carbon and energy source to determine if recalcitrant organic carbon enhances E1 degradation.
158 ay lead to AM fungi obtaining nutrients from recalcitrant organic or mineral sources in the soil, bes
161 ty against Trypanosoma brucei rhodesiense, a recalcitrant parasite that causes the deadly disease Afr
162 lution-precipitation reactions when the most recalcitrant part of the organic matrix is degraded.
163 nteractions will enable researchers studying recalcitrant pathogens, such as animal pathogens where h
171 r prediction, the noninvaded soils receiving recalcitrant Pinus litter had a similar abundance of pla
172 Enzyme activities that improve digestion of recalcitrant plant cell wall polysaccharides may offer s
175 driven by light, both for the degradation of recalcitrant pollutants and for challenging chemical rea
176 efforts have been devoted to degrading this recalcitrant polysaccharide, particularly in the context
177 MOs (LPMOs), enhance the depolymerization of recalcitrant polysaccharides by hydrolytic enzymes and a
179 cleave glycosidic bonds in the two foremost recalcitrant polysaccharides found in nature, namely cel
180 nases (LPMOs) catalyze oxidative cleavage of recalcitrant polysaccharides such as cellulose and chiti
181 particularly powerful in the degradation of recalcitrant polysaccharides such as chitin and cellulos
182 he oxidative cleavage of glycosidic bonds in recalcitrant polysaccharides, such as cellulose and chit
183 ents of enzymatic machineries that decompose recalcitrant polysaccharides, such as chitin and cellulo
184 organic carbon (OC) and black carbon (BC), a recalcitrant product of the incomplete combustion of fos
185 geted use of a biologic for the treatment of recalcitrant psoriatic plaques in patients with less wid
187 ong C-F bonds, these molecules are extremely recalcitrant, requiring advanced treatment methods for e
189 idacloprid, acetamiprid, and clothianidin as recalcitrant sewage constituents that persist through wa
190 ng that relatively fast cycling, rather than recalcitrant, SOC must form the primary target of effort
192 xible alteration of the formerly genetically recalcitrant species L. crispatus, with potential for pr
194 egral component of the plant cell wall, is a recalcitrant substrate against enzymatic challenges by m
196 evolutionary dynamics drove increased use of recalcitrant substrates by the focal species, whereas gr
197 tionary origin of the organisms, turnover of recalcitrant substrates in Antarctic soils, and predicti
198 olysis and to enhance enzymatic digestion of recalcitrant substrates including chitin and cellulose.
199 can contribute to the degradation of complex recalcitrant substrates such as the plant cell wall.
201 ts, suppression of pathogens, degradation of recalcitrant substrates, and robustness of these functio
202 ight contribute to the immunopathogenesis of recalcitrant synovitis in PIRRA, and a possible basis fo
204 sula sediments were bound to black carbon or recalcitrant tar-like organic carbon, thereby lowering p
205 heir potential to stimulate the formation of recalcitrant Tc(IV) biominerals under conditions relevan
206 he implications of the targeted formation of recalcitrant Tc(IV) phases using these proprietorial sub
207 NOT domain, and Arabidopsis vip2 mutants are recalcitrant to Agrobacterium-mediated root transformati
208 creatic ductal adenocarcinoma (PDAC) remains recalcitrant to all forms of cancer treatment and carrie
209 compounds or subject to crystallization were recalcitrant to analysis, so further research is require
214 ing HmsP rendered DeltasagS biofilm cells as recalcitrant to antimicrobial agents as wild-type biofil
216 ich are widespread in eukaryotic genomes but recalcitrant to automated identification because of thei
218 onents of petroleum and have been considered recalcitrant to biodegradation under methanogenic condit
219 For example, the Pioneer inbred PHH5G is recalcitrant to biolistic and Agrobacterium transformati
224 nd nuclear lamina, two compartments that are recalcitrant to classical biochemical purification.
226 a number of heterocyclic substrates that are recalcitrant to conventional peroxide radical initiation
229 chical organization and are postulated to be recalcitrant to conventional treatments, resulting in fa
232 spite its prevalence, the TM7 phylum remains recalcitrant to cultivation, making it one of the most e
233 ion that our indigenous bacteria are largely recalcitrant to culture, many of their functions and phe
239 among coat proteins, this structure has been recalcitrant to detailed biochemical analysis, so molecu
242 wide range of substrates that are otherwise recalcitrant to enzyme-catalyzed reduction, and their po
247 ametophyte of Arabidopsis thaliana, which is recalcitrant to haploid embryo development in culture, a
249 orms share high sequence identity and remain recalcitrant to high-resolution structural studies.
252 to develop a strategy that probes structures recalcitrant to metabolic incorporation and that complem
253 estigations demonstrated that HFO-1234yf was recalcitrant to microbial (co)metabolism and no transfor
258 xidation in air, the incorporated Tc(IV) was recalcitrant to oxidative dissolution with less than 40%
261 e strategy for the analysis of DUBs that are recalcitrant to phage display and other in vitro methods
263 iverse portion of the proteome and are often recalcitrant to purification, impeding studies essential
264 b-containing proteins and peptides that were recalcitrant to reaction with thiol or amine nucleophile
267 ronic biofilm-associated infections that are recalcitrant to resolution by the immune system or antib
268 This allowed the identification of genes recalcitrant to RNAseq analyses by having over- and/or u
274 e shallow and exposed active site has proven recalcitrant to targeting with reversible small-molecule
277 bacute to chronic course and they can become recalcitrant to therapy and lead to physical disabilitie
280 Chronic S. epidermidis infections are often recalcitrant to traditional therapies due to antibiotic
282 eserved ejection fraction (HFpEF) is common, recalcitrant to treatment, and associated with poor outc
287 white rot fungi (WRF) for bioremediation of recalcitrant trace organic contaminants (TrOCs) is becom
288 Pyritization initiated with nucleation on recalcitrant tube walls, proceeded centripetally, decele
290 ancer treatments, such as those for managing recalcitrant tumors like pancreatic ductal adenocarcinom
293 high rate of complete clinical remission in recalcitrant uveitis and is well tolerated by most patie
295 enhance the biophysical properties of other recalcitrant vaccine candidates from emerging pathogens.
298 bial growth, leads to the production of more recalcitrant wastewaters that are difficult to dispose o