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2 of PGC-1alpha transcriptional upregulation, recapitulating a genetic response implicated in exercise
3 Hgf mutant mouse with a small 10 bp deletion recapitulating a human DFNB39 noncoding variant, we demo
6 lt heart, and how they might be more closely recapitulated after injury are critical for our understa
7 s by deleting mitochondrial pyruvate carrier recapitulates age-dependent T cell phenotypes observed i
8 TOR(ECKO) microenvironment was sufficient to recapitulate aging-associated phenotypes, confirming the
9 binant HMGB1 to WT, but not Ripk3(-/-) mice, recapitulates ALI-induced proteolytic collapse of arteri
10 tterned Rho1 activity alone is sufficient to recapitulate all aspects of this morphogenetic event, in
11 cohesion in combination with DAXX deficiency recapitulates all telomeric DSB repair phenotypes associ
12 e the first genetic evidence that mutant S1R recapitulates ALS pathology in vivo while increasing S1R
14 Mesoderm-specific Fgf4/Fgf8 double-mutants recapitulated anterior mesoderm defects and Hh-dependent
15 s in degenerative cerebellar phenotypes that recapitulate aspects of SCA11 including motor coordinati
16 e establishment of a human model system that recapitulates aspects of IPF-associated bronchiolization
17 aive-to-primed transition in hPSC, a process recapitulating aspects of early in vivo embryogenesis.
18 ges in forebrain glutamate and GABA systems, recapitulating aspects of the consequences of early adve
19 uce a cerebrospinal fluid-like secretion and recapitulate barrier functions, thereby inspiring new ad
20 n expanding our biochemical vocabulary is to recapitulate biogenic catalysis using non-natural sequen
21 esponding CRISPR/Cas9 engineered mouse model recapitulated both the clinical and biological phenotype
23 n diseases according to how well they can be recapitulated by animal models and quantify similarities
25 havior outside and inside the midline can be recapitulated by corresponding changes in tension induce
26 was independent of opioid signaling and not recapitulated by NAcSh or dopamine neuron photostimulati
27 these beneficial effects in Pd1-/- mice were recapitulated by repeated i.v. applications of nivolumab
30 ype of UNC93B1-defective phagocytes could be recapitulated by the simultaneous absence of TLR7, 9, an
33 is a complex disease, and individual models recapitulate certain aspects of disease; therefore, the
37 Scnn1b transgenic (Scnn1b-Tg(+)) mice, which recapitulate cystic fibrosis-like mucoinflammatory airwa
38 us-antibody coevolution in macaques can thus recapitulate developmental features of human bNAbs, ther
41 lly, targeted disruption of PTCHD1-AS exon 3 recapitulated diminished miniature excitatory postsynapt
42 s with AP.We observed that 2 endotypes in AP recapitulate disease endotypes previously reported in AR
44 tion of retrosplenial cortex layer 5 neurons recapitulated dissociation-like behavioural effects.
45 bility of 3 chronic stress models in mice to recapitulate distinct aspects of the broad molecular pat
46 newly developed human cell-free systems that recapitulate distinct inter-mitotic and G1 phases and a
47 l models used in the study of ASD frequently recapitulate dysregulation of sleep and biological (diur
48 argets that respond to changes in RBP level, recapitulating effects observed in tethered function ass
50 However, the extent to which regeneration recapitulates embryonic developmental pathways has remai
51 tuations of food availability and whether it recapitulates embryonic mechanisms remain poorly underst
52 er, selective ERK5 kinase inhibitors fail to recapitulate ERK5 genetic ablation phenotypes, suggestin
53 stem cells (ASCs) grow as 3D organoids that recapitulate essential features of the pertinent epithel
54 ped particles and apically as naked virions, recapitulating essential steps of the natural infectious
55 uld show that our coordinate system robustly recapitulates established sensory-limbic and anterior-po
58 l parameter changes, the same model can also recapitulate experimental data for a different PRE/TRE t
60 in vitro expression of mutant dog SOD1 would recapitulate features of human ALS (ie, SOD1 protein agg
61 Moreover, heterozygous Zmym2-deficient mice recapitulated features of CAKUT with high penetrance.
63 el incorporates a self-assembly approach for recapitulating features of bladder cancer invasion in 3D
65 oluble, nonfibrillizing Abeta (1-30) peptide recapitulates full-length Abeta stereoselective cellular
67 te whether the loci of individual deviations recapitulated group-average brain maps of schizophrenia
68 ling using reasonable biophysical parameters recapitulated growth-dependent SBF/MBF clustering and pr
69 the infarcted, border and remote zones), and recapitulate hallmarks of myocardial infarction (in part
71 stent with physiological human microglia and recapitulate heterogeneity of adult human microglia.
72 harmacological and genetic studies, we could recapitulate high shear stress effects on isolated human
73 t bacteria are likely to diverge in patterns recapitulating host phylogeny when hosts undergo allopat
74 culture model, primary astrocytes may better recapitulate human disease, are easier to maintain than
76 ools for HFpEF, including animal models that recapitulate human HFpEF, and human studies that both ad
81 -Cas9 generated Gaa(c.1826dupA) murine model recapitulates hypertrophic cardiomyopathy and skeletal m
85 ical features of AD in GiDs are consistently recapitulated in a three-dimensional culture AD model, v
87 ne modification level, that can be partially recapitulated in an orthogonal cell line system by the i
89 The robust performance of these PGSs were recapitulated in four independent microarray datasets fr
92 This spontaneous autoimmune phenotype was recapitulated in mice lacking beta1,6N-acetylglucosaminy
93 ation phenotype; this phenotype is partially recapitulated in murine Dnmt3a (-/-) bone marrow cells.
96 histopathologic results from the patient are recapitulated in the hearts from R405W-desmin knock-in m
99 ins unclear to what degree transport will be recapitulated in the substantially larger and more compl
101 ffects of MORs on synaptic transmission were recapitulated in two sets of independently engineered is
102 pression observed in KSHV-infected cells was recapitulated in uninfected endothelial cells by the exo
103 of wound-response growth restriction can be recapitulated in unwounded plants when the LOX3 pathway
105 , we used the nuclear Auxin Response Circuit recapitulated in yeast (Saccharomyces cerevisiae) system
106 he non-human primate model, and do not fully recapitulate increased EE seen in rodent and in vitro st
107 onal framework was successfully developed to recapitulate individual patient evolutionary dynamics, w
108 granulin in microglia alone is sufficient to recapitulate inflammation, lysosomal dysfunction, and hy
109 three real datasets, we demonstrate that cLV recapitulates interactions between relative abundances i
110 ay traces generated from these distributions recapitulate intermolecular background coupling paramete
111 We first show that "C-Pro-only" constructs recapitulate key aspects of the behavior of full-length
113 ary normalization weights, some of which can recapitulate key experimental observations of the dynami
114 st previously studied SHIVs, however, do not recapitulate key properties of transmitted/founder (TF)
116 specific T cell engager-induced toxicity and recapitulates key features similar to those in human cyt
117 uman physiologies and pathologies by closely recapitulating key characteristics and functions of in v
118 en) and multiplex (DCyFIRplex) DCyFIR modes, recapitulated known GPCR agonism with 100% accuracy, and
119 disease- and drug-specific communities also recapitulated known pathways for those given diseases an
122 rine model of perforin-deficient CAR T cells recapitulated late-onset inflammatory toxicities occurri
124 ikewise, feeding protocols were optimized to recapitulate longevity outcomes typical of standard plat
126 specific approach for TBI in Drosophila that recapitulates mammalian injury phenotypes and underscore
128 zation, and the formation of inclusions that recapitulate many of the biochemical, structural, and or
130 ional cell culture techniques, which fail to recapitulate mechanobiologic stimuli known to affect ves
132 erum from trauma-exposed males into controls recapitulates metabolic phenotypes in the offspring.
134 ng transcription factors, SOX2 and SOX9, and recapitulate more primitive transcriptional programs spa
136 ether with surface effects, is sufficient to recapitulate much of the large-scale morphology and dyna
137 u/Lbu mouse model on the F2 mixed background recapitulates multiple human LPI phenotypes and may be u
141 g biologically inspired design principles to recapitulate native crypt-villi topography and luminal f
146 C exhibited four tumor subpopulations, three recapitulating normal epidermal states, and a tumor-spec
147 ine the extent to which global processes are recapitulated on local scales and how accurately experim
149 7 messenger RNA (mRNA) fivefold but does not recapitulate optic nerve loss; however, SE(del)/knockout
155 tem with no motor features, but mouse models recapitulating PAF without motor dysfunction are lacking
156 s aimed at elucidating cancer biology do not recapitulate pathobiology including tumor heterogeneity,
158 actions through a strategy that allows us to recapitulate photoredox-like reactivity in the absence o
159 the microscopic scale alone is sufficient to recapitulate previously observed behavior of pigment org
160 ' capture scRNAseq analysis of PBMC not only recapitulated previously published reports by detecting
162 tooth eruption in molars, which essentially recapitulate primary failure of eruption in humans, a ra
163 ecific SigMap for lung adenocarcinoma, which recapitulated published KRAS biology, identified novel s
164 ndividual approaches and outperforms them in recapitulating published drafts in a fast and repeatable
165 netic alterations of BCL2, NOTCH2, and MYD88 recapitulated recent studies showing good, intermediate,
167 olescent stress led to circuit deficits that recapitulates schizophrenia, whereas adult stress induce
169 e (M) and 7,12-dimethylbenz[a]anthracene (D) recapitulate several key features of human luminal B HR(
170 ast SG reconstitution system that faithfully recapitulates SG assembly in response to trigger RNAs.
171 bited concurrent skin and joint changes that recapitulate some features found in human psoriatic skin
172 e a human neuronal cell model of HD that may recapitulate some of the earliest stages of HD pathogene
173 ockout mouse model and found that this model recapitulates some of the neurological phenotypes of BBS
182 72 from myeloid cells alone is sufficient to recapitulate the age-dependent lymphoid hypertrophy and
184 laboratory models of cancer are designed to recapitulate the biochemical and biophysical characteris
185 We engineered patterned substrates that recapitulate the biophysical properties of the early emb
186 mouse models of allergic airway disease that recapitulate the cardinal clinical features of human all
187 s shown some benefit, but it is difficult to recapitulate the complex set of factors required to form
188 to our knowledge the first of its kind, can recapitulate the compressive forces on the cerebellar co
189 ing loss-of-function mutations in PKHD1 also recapitulate the cystic phenotype associated with autoso
190 substitutions of Ser-561 and Ser-641/Thr-642 recapitulate the depolarizing shift in activation and re
191 abilization using hypoxia mimetics, does not recapitulate the effect of hypoxia on FN matrix reorgani
192 ion treatment with gut hormone analogs might recapitulate the efficacy and mitigate the significant r
194 dy physiology, and at the same time, fail to recapitulate the extensive features of the tumor stroma.
195 ed that bursting alone cannot quantitatively recapitulate the formation of the stripe and that contro
197 ancer research, but the extent to which they recapitulate the heterogeneity observed among malignant
199 eral significant barriers such as failure to recapitulate the human TME in animal models and issues w
201 the cachexia field lacks animal models that recapitulate the long-term kinetics of clinical disease,
203 ed in vitro-as well as those of the mouse(4)-recapitulate the oscillations of the segmentation clock.
205 that rectal cancer organoids (RCOs) closely recapitulate the pathophysiology and genetic changes of
206 pregnane X receptor, which was sufficient to recapitulate the phenotype observed in mutant mice.
207 nhibition of HSP90 reversed these effects to recapitulate the phenotype of a JA-insensitive mutant la
208 and the limitations of current cell lines to recapitulate the phenotype, functional and molecular cha
209 Rho-Cre(+) mice, but the phenotype does not recapitulate the phenotypic severity observed in young c
210 ome, using a Cep290-deficient mouse model to recapitulate the phenotypic variability observed in pati
211 mozygous (Tubb4a(D249N/D249N)) mutation that recapitulate the progressive motor dysfunction with trem
212 hed in humans, murine models failed to fully recapitulate the reproductive and olfactory phenotypes o
213 u-NSG mice) and infected with HIV-1(ADA) can recapitulate the salient features of this progressive hu
215 dition, we designed a microfluidic system to recapitulate the shear rate conditions before and after
216 int mutations, even when combined, failed to recapitulate the single or double null mutant phenotypes
217 animals across six sub-cellular locations to recapitulate the spatial organization of tropane alkaloi
218 ntal models seek to mimic these processes to recapitulate the steps of tissue fate acquisition and mo
220 phenotypically distinct from each other and recapitulate the tau immunophenotypes encountered in age
221 Abeta42 peptide, but these 2D models do not recapitulate the three-dimensional (3D) architecture of
222 sess the capacity of each stress paradigm to recapitulate the transcriptional organization of gene ne
226 ased connectivity analysis with the striatum recapitulated the cingulate-striatum relationship observ
228 nd 339-378 that, when introduced in 88hIgG1, recapitulated the direct cell killing and avidity of 88m
229 pression of FNDC3A in cells that had lost it recapitulated the effects of FAM46C, inducing aggregates
230 ncing of HDAC3 expression with siRNA largely recapitulated the effects of HDAC3/6i on mRNA levels of
231 n analyses revealed that VAT transplantation recapitulated the effects of obesity on microglial activ
233 Transcriptional perturbation experiments recapitulated the exclusion of B. mori centromeres from
234 pluripotent stem cell-derived cardiomyocytes recapitulated the hypertrophic phenotype and uncovered a
237 y infiltrated by recipient leukocytes, which recapitulated the liver myeloid and lymphoid composition
239 d the molecular phenotype, measured by CAGE, recapitulated the observed cellular phenotypes while pro
241 In vitro differentiation of CD34(+) cells recapitulated the patient's clinical arrest in granulopo
242 rtensinogenic microbiota to gnotobiotic mice recapitulated the prebiotic-deprived hypertensive phenot
243 atent trace was reignited into activity that recapitulated the previous stimulus representation.
246 and cristae organizing system (MICOS), fully recapitulates the AI profile observed when AIF is inhibi
247 a pseudocolorization scheme that accurately recapitulates the appearance of cells under conventional
248 de of the central nervous system parenchyma, recapitulates the beneficial effects of total P2X7R depl
251 Discrete phylogeographic analysis largely recapitulates the documented spread of the HIV types, wh
252 Expression of activated AKT in tumor cells recapitulates the effects of fibroblasts resulting in su
254 te stress-induced photoreceptor degeneration recapitulates the epigenetic hallmarks of human AMD.
255 o a competitive surface exchange model which recapitulates the experimental observation that fibrinog
257 lt-born neurons using a Cup/Rap model, which recapitulates the hippocampal demyelination that occurs
258 cavity leads to a highly aggressive MM that recapitulates the histological features and gene express
260 e present a microphysiological platform that recapitulates the key structure and function of the huma
261 ized transplantation model of PD that better recapitulates the main disease features, obtained by coi
262 al fracture orthopaedic injury model in mice recapitulates the major manifestations of complex trauma
264 itic health in a rodent model of HAND, which recapitulates the neuroinflammatory state of virally con
265 lemented a physical model of the system that recapitulates the observed spindle-cortex interactions.
267 ocompetent syngeneic mouse model that better recapitulates the phenotype and clinical features of hum
268 a Nup1 mutant lacking 36 C-terminal residues recapitulates the phenotypes of the Nup1-LexA fusion ind
271 rms for modeling development and diseases by recapitulating the architecture of the embryonic brain.
272 liquid crystal elastomer (LCE) particles by recapitulating the biophysical patterning mechanism that
274 ent of an in-vitro mimic of the BBB requires recapitulating the correct phenotype of the in-vivo BBB,
275 Altogether, eMSCs provide a unique platform recapitulating the full spectrum of cDC subsets enabling
281 Genetically engineered mouse models of HGSC recapitulating the likely cell of origin (fallopian tube
282 he initiation of feeding and drinking (fully recapitulating the symptoms of gastric distension) in pa
283 se ICNs in an independent cohort of HCs, and recapitulated their functional relevance with a post hoc
286 ing in a single oxidative stress network, we recapitulated these observations and made predictions ab
294 lls (ESCs) and trophoblast stem cells (TSCs) recapitulates this process, forming embryo-like structur
297 rgan Chip) microfluidic culture devices that recapitulate tissue-tissue interfaces, fluid flows, mech
298 ions perturbed in Alzheimer's disease can be recapitulated using iPSC-derived cells in vitro, and co-
300 initial but not established infection can be recapitulated without latency and depends only on the ab