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1 (MHC class I-like located near the leukocyte receptor complex).
2 interaction of a Tat substrate with the Tat receptor complex.
3 tegral signaling components of the B cell Ag receptor complex.
4 e activated FLAGELLIN-SENSING2 (FLS2) immune receptor complex.
5 al signaling events downstream of the T-cell receptor complex.
6 ion of Tat precursor proteins with the TatBC receptor complex.
7 recruits IL-4Ralpha to form a heterodimeric receptor complex.
8 on molecular-dynamics simulations of a micro-receptor complex.
9 obivalent ligands interact with the putative receptor complex.
10 ction of a viral surface protein with a host receptor complex.
11 the process by reducing the stability of the receptor complex.
12 ts of 7DHC on the formation of an active Wnt receptor complex.
13 subsequent activation of the OsBRI1-OsSERK1 receptor complex.
14 , which can orient and stabilize the peptide-receptor complex.
15 components of the same multimolecular T-cell receptor complex.
16 of the TSHR, its ligand TSH, and the hormone-receptor complex.
17 te the internalization of the Tf-TfR1 ligand-receptor complex.
18 helial cells express constituents of the IL2 receptor complex.
19 f the tyrosine phosphatase SHP-1 to the CD16 receptor complex.
20 Tyk2 deficiency can be rescued via the IL-22 receptor complex.
21 ion of a heterotypic, oligomeric, active Eph receptor complex.
22 ges to appropriately activate or inhibit the receptor complex.
23 /MD-2 and antagonize activation of the human receptor complex.
24 for recognition by the Crm1-Ran(GTP) nuclear receptor complex.
25 uggesting that Miro is also part of a Parkin receptor complex.
26 ferentiation occurs through the NgR1/Lingo-1 receptor complex.
27 effects through activation of the TLR4/MD-2 receptor complex.
28 so detected using flow cytometry, as was its receptor complex.
29 4+ neurons expressing the GFRalpha1-RET GDNF receptor complex.
30 ons, and an integral component of the Sema3F receptor complex.
31 treatments, all of which target the hormone-receptor complex.
32 tner CD19 are core subunits of the B cell co-receptor complex.
33 despite accounting for half of the antibody-receptor complex.
34 phorylation upon Axin recruitment to the Wnt receptor complex.
35 ate oligomerization of TatB within the TatBC receptor complex.
36 2) and LLG3, as co-receptors in the BUPS-ANX receptor complex.
37 and structure of NAM binding pockets in the receptor complex.
38 that mediates IL-37 binding to the TGF-beta receptor complex.
39 rtion of a Tat signal peptide into the TatBC receptor complex.
40 f membrane proteins GPR124 and RECK with Wnt receptor complexes.
41 eded efforts aimed at crystallizing cytokine-receptor complexes.
42 with constant formation and dissociation of receptor complexes.
43 s the alphaIIbbeta3 and alphavbeta3 integrin receptor complexes.
44 ical for the signaling functions of multiple receptor complexes.
45 able and conformationally homogeneous ligand-receptor complexes.
46 BAK1 activation in surface-localized immune receptor complexes.
47 occurs upon cocaine binding to sigma1-D1-H3 receptor complexes.
48 merging treatments that target TH2-promoting receptor complexes.
49 eath receptors through formation heteromeric receptor complexes.
50 rimer) not previously observed for other HAd-receptor complexes.
51 olution structures of the ligand/co-receptor/receptor complexes.
52 reserved responses to ligands of a series of receptor complexes.
53 ), defined in terms of stability of an anion-receptor complex (1 + X(-)) against its disintegration,
55 mode and that the respective covalent ligand-receptor complexes activate G proteins comparable to the
57 ighlights the key components of the estrogen receptor complex alongside a novel interaction with GRHL
59 zation of the MSD in its native, full-length receptor complex and a recombinant, unglycosylated MSD i
60 tionally crucial for the formation of ligand-receptor complex and as they replaced evolutionarily hig
61 ritical link between the pattern-recognition receptor complex and calcium-dependent immunity programs
62 that MYCs acting downstream of the jasmonate receptor complex and calmodulin-binding transcription ac
63 ibitor that interferes with the KCTD/GABA(B) receptor complex and efficiently isolates endogenous KCT
65 precise mechanisms by which HCV exploits the receptor complex and host machinery to enter the cell re
66 on, PACRG was recruited to the activated TNF receptor complex and interacted with LUBAC components.
67 on of ATF-2 by separately inhibiting the TNF receptor complex and JNK pathway through a negative feed
68 e-directed mutagenesis analysis of the CD16A receptor complex and now report that the association of
69 component and substrate organization in the receptor complex and on the structure of the pore comple
71 iated stronger signaling through the IL-2/15 receptor complex and provided cell function advantages.
72 s, express a functional interleukin-1 (IL-1) receptor complex and respond with NF-kappaB activation a
73 caffolding function of Jak2 within the IFNGR receptor complex and reveal that Jak1 can mediate a semi
77 receptor encoded within the human leukocyte receptor complex and syntenic region of mouse chromosome
78 what enables the recruitment of Dvl-2 to the receptor complex and the initiation of the Wnt pathway.
79 oss-of-function mutation of the TGF-beta/BMP receptor complex and the second to increased signaling s
80 the cell regulate formation of the arrestin-receptor complex and thereby G protein-independent signa
82 of the TatB and TatC units within the TatBC receptor complex and with TatA entering the interior Tat
83 artition between two discrete populations of receptor complexes and approximately 1.5 MDa supercomple
84 sosomal degradation, and recycling of ligand-receptor complexes and cell adhesion molecules from the
85 gand-gated ion channel and G protein-coupled receptor complexes and discuss strategies for their phar
86 These GTPases promote internalization of Wnt receptor complexes and play a critical role in intestina
87 We describe structures of select adhesion receptor complexes and their assembly into larger interc
88 he glycan effect extended to RAMP-CTR amylin receptor complexes and was also conserved in the related
89 le required for the stability of the TGFbeta receptor complex, and a new mechanism by which the extra
91 L-12 signals via the IL-12Rbeta1.IL-12Rbeta2 receptor complex, and IL-23 uses also IL-12Rbeta1 but en
92 ED KINASE1 (BIK1) of the pattern-recognition receptor complex, and this triggers an increase in the c
93 identified a functional IL-10R2 homodimeric receptor complex, and uncovered broad receptor cross-tal
96 (MD-2), the coreceptor within the TLR4/MD-2 receptor complex, as the high-affinity sCD83 binding par
97 of endocrine fibroblast growth factor (FGF) receptor complexes, as they are required for the high-af
102 coactivator activities to engage the nuclear receptor complex at different steps of transcription.
103 ensional tracking of epidermal growth factor receptor complexes at a depth of approximately 100 mum i
106 ng the putative heteromeric 5-HT(2A)/mGlu(2) receptor complex, based on the 5-HT(2A) antagonist MDL-1
108 -acting antidepressants that act at the NMDA receptor complex, but without dissociative and psychotom
109 redoxin 6 (PRDX6) is recruited to the opioid receptor complex by c-Jun N-terminal kinase (JNK) phosph
110 2 of CXCR4 and depletion of the heteromeric receptor complexes by CXCR4 knockdown inhibit alpha1-AR-
111 TRAIL responses involves clustering of death receptor complexes by E-cadherin and the actin cytoskele
112 te the structures of 10 distinct native AMPA receptor complexes by single-particle cryo-electron micr
113 most receptor complexes, they exemplify how receptor complexes can be drugged, and lay the groundwor
114 se that this concept may explain why agonist.receptor complexes can be inactive and that adopting mul
115 r mutagenesis, we show that inactive agonist.receptor complexes can result from agonist binding to th
116 k by which local upregulation of MIF and its receptor complex CD74/CD44 mediate glomerular injury and
119 isms, initiated by distinct ligand-activated receptor complexes, complement Smad signaling and thus c
120 this process, a pollen tube surface-located receptor complex composed of ANXUR1/2 (ANX1/2) and Buddh
121 acellular protein mediators and the synaptic receptor complex composed of cellular prion protein (PrP
122 IL-31-induced signaling is mediated by a receptor complex composed of oncostatin M receptor beta
123 (IFN-lambdas) signal through a heterodimeric receptor complex composed of the IFN-lambdaR1 subunit, s
124 amino acid isoleucine and perceived by a co-receptor complex composed of the Jasmonate ZIM-domain (J
126 ctionality, and architecture of internalized receptor complexes composed of a single GPCR, beta-arres
127 aleimide sensitive factor attachment protein receptor) complex, composed of synaptobrevin, syntaxin,
128 An evolutionarily ancient plant hormone receptor complex comprising the alpha/beta-fold hydrolas
129 Rab7, and its effector, PLEKHM1; and a SNAP receptor complex consisting of Syntaxin 13, Snap29, and
130 S development and kidney morphogenesis via a receptor complex consisting of the glycerophosphatidylin
131 luble alpha receptor subunit p40, binds to a receptor complex consisting of the IL-23 receptor (IL-23
133 ed through interactions with a multi-subunit receptor complex containing IL2Ralpha, IL2Rbeta, and IL2
134 ated to the shoot where they bind to a shoot receptor complex containing the leucine-rich repeat rece
135 explored whether the stability of the IL-10 receptor complex contributes to the immunomodulatory pot
136 he gradual accumulation of long-lived active receptor complexes contributes to the increased intrinsi
137 cific structural rearrangements in the virus-receptor complex could help to trigger the irreversible
138 ergent signaling output from multifunctional receptor complexes critically depends on distinct signal
139 docytic machinery, composed of the scavenger receptor complex Cubilin/Amnionless and Dab2, that is re
140 g link by showing that a pattern recognition receptor complex directly associates with and activates
142 blockade of mu opioid receptor or Toll-like receptors complex failed to alter, while blockade of per
143 was unexpectedly found to not depend on such receptor complexes for its activity, which was induced w
144 We built structural models of TARP-AMPA receptor complexes for TARPs gamma2 and gamma8, combinin
145 of PAMP-triggered immunity by limiting BAK1-receptor complex formation in the absence of ligands.
146 ffered in their ligand specificities, ligand-receptor complex formation in tissues, and receptor shed
148 strom crystal structure of the Vif substrate receptor complex from simian immunodeficiency virus isol
151 ate genes that encode for a ligand (NDP) and receptor complex (FZD4, LRP5 and TSPAN12) in the Norrin
152 are found within four genes that encode the receptor complex (FZD4, LRP5, and TSPAN12) and ligand (N
154 R gamma-chain, and the von Willebrand factor receptor complex GPIb-IX-V, which are essential for thro
155 e-based activation motif-containing collagen receptor complex GPVI-FcR gamma-chain, and the von Wille
157 GF19 signaling through the FGFR4/beta-klotho receptor complex has been shown to be a key driver of gr
159 receptor genes encoded within the leukocyte receptor complex have both been expanded and diversified
163 diately after the recruitment of RIP1 to the receptor complex, impairing IkappaB kinase (IKK) recruit
166 ling data indicate a role for the quaternary receptor complex in regulating the balance between TGF-b
168 er function by catalysing the formation of a receptor complex in the plasma membrane consisting of va
169 he formation of the PLP-alphav integrin-AMPA receptor complex in vivo and whether complex formation i
170 w reports new strategies and tools to obtain receptor complexes in a near-native state, revealing ins
171 resolve the differential composition of AMPA receptor complexes in brain regions and through developm
172 Artemin through specific activation of their receptor complexes in distinct subsets of lumbar motor n
173 ling pathways, the formation of higher order receptor complexes in lipid rafts is an equally importan
176 of NMDA receptors as MK-801 binding and NMDA receptor complexes in postsynaptic density (PSD) were in
177 recruitment and the stability of arrestin-3 receptor complexes in real time using fluorescence reson
179 vior of CD3zeta, a subunit of the CD3 T cell receptor complex, in resting and activated primary human
180 5a regulates the subcellular localization of receptor complexes, including Ror2 homodimers, Ror2/Fzd7
181 he epithelial cells via the IL-22RA1-IL-10R2 receptor complex inducing changes in the expression of g
182 on by CAP-PEs includes assembly of TLR2/TLR1 receptor complex, induction of downstream signaling via
183 tion of Lck kinase, PLC-gamma1 or the T cell receptor complex inhibits light-evoked Ca(2+) transients
186 ation and induces internalization of the NDP receptor complex into the endo-lysosomal compartment.
188 e introgression signatures include olfactory receptor complexes into both species, hypertension resis
189 as a BMP2/BMP4 co-receptor, recruits the BMP receptor complexes into raft microdomains, and positivel
190 uch as lipid rafts, protein-lipid complexes, receptor complexes, invadopodia, and other cellular stru
191 ase, that is a component of an intracellular receptor complex involved in the detection of the smoke
192 hat mediates inflammation by engagement of a receptor complex involving the components CD74, CD44, CX
193 C G protein-coupled receptor T1R1/T1R3 taste receptor complex is an early amino acid sensor in MIN6 p
197 ore a measure of the average time the ligand-receptor complex is present and is quantified using the
198 rotein 5-6 (LRP5-6)/tetraspanin 12 (TSPAN12) receptor complex is required for developmental vasculari
199 .myeloid differentiation factor 2 (MD-2) LPS receptor complex is strongly activated by hexa-acylated
200 Cell-cell communication mediated by ligand-receptor complexes is critical to coordinating diverse b
202 CD19, a signaling component of the B cell receptor complex, is one of multiple regulators driving
203 signaling inhibits PP2C activity through ABA-receptor complex, it remains unknown if other mechanisms
205 n we established that signaling through this receptor complex leads to activation of the transcriptio
206 rmone-dependent formation of the COI1-JAZ co-receptor complex leads to ubiquitination and proteasome-
207 obile signal, which triggers SAR through its receptor complex LecRK-VI.2/BAK1 in Arabidopsis thaliana
211 Abnormal regulation of the FGFR1-Klotho receptor complex may cause a resistance to the phosphatu
212 ion of a serine protease-pattern recognition receptor complex, MBL-associated serine protease (MASP)-
213 Although the role of the megalin-cubilin receptor complex (MCRC) in this process is unequivocal,
214 ng, structural and mechanistic insights into receptor complexes mediated by IL-23, and by IL-12 famil
215 inding, the environment of 3-I-Tyr(B26) in a receptor complex must differ from that in the free hormo
217 dentify the target of NS1 as the mRNA export receptor complex, nuclear RNA export factor 1-nuclear tr
218 hizobium LCOs are perceived by a heteromeric receptor complex of distinct Lys motif (LysM)-type trans
219 as proNGF induces apoptosis via binding to a receptor complex of the common neurotrophin receptor (p7
221 l presentation and activation of heteromeric receptor complexes of transmembrane, dual-specificity ki
223 horins signal through neuropilin-2/plexin-A1 receptor complexes on post-crossing commissural axons to
224 nes exert their function by binding specific receptor complexes on the surface of immune cells and ac
225 inhibitors can interact with either the Nogo receptor complex or paired immunoglobulin-like receptor
226 N-induced T cell activation, and that direct receptor complex-particle interactions are permitted bot
227 interaction of Tat signal peptides with the receptor complex plays a critical role in the transport
228 ranged Igh allele assembles into a PreB cell receptor complex (PreBCR) to generate signals to initiat
229 wo different receptor subunits in a cytokine-receptor complex, precisely as the receptors are dispose
230 esting that endocytosis of non-canonical Wnt/receptor complexes preferentially takes place at the api
231 ody coupling leads to a fully active ternary receptor complex present in amounts correlating directly
233 ting key protein-protein interactions within receptor complexes provides an opportunity to develop mo
235 ponses, the mechanism by which the TLR4-MD-2 receptor complex recognizes these changes is not well un
236 her, we have demonstrated that the TLR4-MD-2 receptor complex recognizes variation in lipid A molecul
240 Hh to the Patched-Interference Hh (Ptc-Ihog) receptor complex relieves Ptc inhibition on Smoothened (
242 rovide a template for modulating the GABA(B) receptor complex, revealing a fundamentally novel approa
244 In platelets, the glycoprotein (GP) Ib-IX receptor complex senses blood shear flow and transmits t
245 drophobic pocket of MD-2, inducing an active receptor complex similar to that induced by lipid A.
246 Our study provides insights into how IL-10 receptor complex stability fine-tunes IL-10 biology and
247 CR-triggering models invoke an alteration in receptor complex structure as the initiating event, but
249 with in vitro stabilities of ternary ligand.receptor complexes, suggesting a threshold mean lifetime
250 link between BCL9/B9L, PYGO2 and nuclear co-receptor complexes suggests that these beta-catenin co-f
252 atB and TatC form an oligomeric, multivalent receptor complex that binds Tat substrates, while multip
253 structural organization effect of the anion receptor complex that changes the nature of the combined
255 a multigene family encoded by the leukocyte receptor complex that encodes a variety of receptors tha
256 ltiprotein intracellular pattern recognition receptor complex that facilitates the cleavage and secre
257 aemia inhibitory factor (LIF) signal through receptor complexes that are critically dependent on gp13
258 th other G-protein-coupled receptors to form receptor complexes that can amplify or decrease the sign
259 an be attributed to binding of galectin-8 to receptor complexes that positively (uPAR and MRC2) and n
260 d by combinatorial interactions with dynamic receptor complexes that vary more than initially thought
262 RBPJ, as well as the interleukin-15 (IL-15) receptor complex, the latter enhancing IL-15 autocrine s
264 COI1 is an essential component of the JA co-receptor complex, the null coi1-1 mutant is male sterile
265 y protein-protein interaction of the GABA(B) receptor complex-the interaction with KCTD proteins.
266 hese include differences between the antigen receptor complexes themselves and the spatial separation
267 re still in preclinical development for most receptor complexes, they exemplify how receptor complexe
268 cell wall is integrated at the level of the receptor complex through interaction with RECEPTOR-LIKE
269 es the binding affinity of IL-37 to the ALK1 receptor complex, thus allowing IL-37 to signal through
270 ants needed to bind to a functional cytokine receptor complex to constitutively activate STAT5, JAK3(
272 gs are proposed to form a heteromeric netrin-receptor complex to mediate a chemorepellent response.
273 tributions of proximal regulators of the Wnt receptor complex to these processes remain undefined.
274 iased agonist that selectively engages these receptor complexes to activate Galphaq and thus phosphol
275 Furthermore, p52ShcA sequestered TGF-beta receptor complexes to caveolin-associated membrane compa
276 ormational change that ultimately allows the receptor-complex to be recognized by the COPI system.
277 e also interacts with the immunosurveillance receptor complex, Toll-like receptor 4 (TLR4), on microg
280 Moreover, perception of flg22 by its cognate receptor complex triggers actin remodeling through the a
282 role in transmitting signals to the Integrin receptor complex, we conducted genetic studies in Drosop
284 le most studies focus on its role in the TNF-receptor complex, we here identify a novel component in
285 Based on the recent structure of a "micro-receptor" complex, we predict that 3-I-Tyr(B26) engages
286 cytosolic effector proteins recruited to the receptor complex were unambiguously quantified by fluore
287 capable of binding and activating the T cell receptor complex), were either immobilized or able to di
288 at Nephrin transmits signals to the Integrin receptor complex, which mediates podocyte adhesion to th
289 This is particularly relevant to the GABA(B) receptor complex, which plays a prominent role in many b
290 ptor regulatory proteins (TARPs), yielding a receptor complex with altered gating kinetics, pharmacol
291 lose paralogue Brother of Ihog (Boi) forms a receptor complex with Patched to mediate intracellular H
292 terminal WRKY DNA binding domain and forms a receptor complex with RPS4, another NB-LRR protein.
295 e overlap with that seen for the neonatal Fc receptor complexed with enterovirus E6 but is larger and
296 esent crystal structures of a mammalian P2X7 receptor complexed with five structurally-unrelated anta
297 ers of TatB and TatC form circular substrate-receptor complexes with a central binding cavity for twi
298 tion assay, CXCR7 was found to engage in MIF receptor complexes with CXCR4 and CD74, both after ectop
299 and on the frictional coupling of the ligand-receptor complexes with the actin cytoskeleton, the memb
300 ologic functional impact of this cross-class receptor complex without interfering with the function o