ライフサイエンスコーパス: receptor molecule

1 ough it did not require cell surface HS as a receptor molecule.

2 2B and NR2D subunits may be part of a single receptor molecule.

3 nd and distal 3rd intracellular loops of the receptor molecule.

4 resence of these two domains within a single receptor molecule.

5 d to be regulated by sialylation of the CD22 receptor molecule.

6 sensory neurons that express a given odorant receptor molecule.

7 min B9-binding pocket of an ancestral folate receptor molecule.

8 -biasing lesions at various locations in the receptor molecule.

9 ular conformational coupling within a single receptor molecule.

10 output consequences in other regions of the receptor molecule.

11 an be achieved even at the level of a single receptor molecule.

12 anscription activation are integrated at the receptor molecule.

13 ted sensory neurons express a single sensory receptor molecule.

14 mination between surface-exposed and soluble receptor molecules.

15 proteins to tyrosine-phosphorylated sites on receptor molecules.

16 the initiation of signaling by many types of receptor molecules.

17 ignaling control when teamed with functional receptor molecules.

18 ing allosteric coupling of multiple CheA and receptor molecules.

19 idence for the close proximity of individual receptor molecules.

20 ber-fibritin proteins targeted to artificial receptor molecules.

21 ducing the homodimerization of two identical receptor molecules.

22 igand binding regions in mutant and chimeric receptor molecules.

23 o-oligomeric ligands binding to and bridging receptor molecules.

24 context of functional chimeric hCCR-5/mCCR-5 receptor molecules.

25 ha induced rapid endocytosis of cell surface receptor molecules.

26 effect by expanding the population of active receptor molecules.

27 uses interact with two putative cell surface receptor molecules.

28 ntaining the basolateral localization of the receptor molecules.

29 89 logK(ass) values are listed for 100 anion receptor molecules.

30 bind epitopes within one or across two CXCR2 receptor molecules.

31 in Stentor along with general properties of receptor molecules.

32 and kainate receptors at the level of single receptor molecules.

33 posite ends through which it brings together receptor molecules.

34 itectures which function as H-bonding, anion receptor molecules.

35 r-like rotation and self-rotation of the two receptor molecules.

36 tion of serotonin with at least 15 different receptor molecules.

37 , we identify key features of the underlying receptor molecules.

38 naling requires structural studies on intact receptor molecules.

39 creased or polarized expression of toll-like receptor molecules.

40 volve a binding interaction between CheR and receptor molecules.

41 for CT in PDMS microchips with cell surface receptor molecules.

42 in the expression of G-proteins and odorant receptor molecules.

43 s functionalized with DNA aptamers to act as receptor molecules.

44 ng of the extracellular domain of the second receptor molecule after forming the 1ratio1 complex.

45 nteractions, we tested a soluble dodecameric receptor molecule and found that it neutralized primary

46 d using capture HbA1c antibody as a specific receptor molecule and the QD-labeled secondary antibody

47 lasses of odorants via different families of receptor molecules and G-proteins corresponding to the m

48 egrade extracellular matrix and cell surface receptor molecules and have an essential function in mal

49 d neighboring cells by expressing ligand and receptor molecules and play a key role in cellular devel

50 eceptor changes, causing a dispersion of the receptor molecules and subsequent shrinking of the struc

51 ghly diverse CDR3 loops found in all antigen receptor molecules and suggest that such regions form th

52 receptor subunits, the composition of native receptor molecules and their localization in the brain h

53 interest are the first structures of T cell receptor molecules and, particularly, TCR-ligand complex

54 ormable membrane containing freely diffusing receptors molecules and long repeller molecules that inh

55 tein-1 (LMP1) mimics a constitutively active receptor molecule, and has been shown to activate NF-kap

56 establish hydrophobic interactions with the receptor molecule, and mutations at these hydrophobic re

57 e biorecognition of ligands, antibodies, and receptor molecules; and unified point-of-care integratio

58 T cell progenitors lacking antigen receptor molecules are also blocked in differentiation a

59 in contact with flat substrates coated with receptor molecules are calculated using a Johnson, Kenda

60 ect C. elegans and that the C. elegans Cry5B receptor molecules are glycolipids.

61 by multiple weak homotypic contacts between receptor molecules are responsible for regulating normal

62 on receptors indirectly only when enzyme and receptor molecules are sterically close, possibly formin

63 ity is encoded within the DEF segment of the receptor molecule, as evidenced by the suppression of a

64 f the total PDGF beta receptor, that not all receptor molecules associated with the E5 protein were t

65 n of a complex and possibly ordered array of receptor molecules at cell contact sites.

66 d by the thymic stroma and the requisite BMP receptor molecules (BMPR-1A, BMPR-1B, BMPR-II), and sign

67 tinal rods signal the activation of a single receptor molecule by a photon.

68 Occupation of the receptor molecule by the ligand (TSH) resulted in a dose

69 -beta receptor, rendering the PDGF type-beta receptor molecule capable of autophosphorylation in resp

70 ce expression of one or all of the candidate receptor molecules (CD81, low-density lipoprotein recept

71 ntibody recognizing the full-length estrogen receptor molecule (clone 6F11), we performed immunohisto

72 ly lower expression of p30/p46 NK-activating receptor molecules compared with those of control subjec

73 es dimerization and activation of a chimeric receptor molecule composed of the extracellular domain o

74 ynapses, numerous structural, signaling, and receptor molecules concentrate at the postsynaptic densi

75 Thus, it is possible that a single leptin receptor molecule could have two functional ligand bindi

76 While the ligands sorted to lysosomes, no receptor molecules could be detected there, and no recep

77 n prolactin (hPRL) binds two human prolactin receptor molecules, creating active heterotrimeric compl

78 scale to the absolute logKass values of two receptor molecules, determined independently by direct m

79 V2R- and OR-type receptor molecules do not colocalize in one cell, and on

80 Murine cells lack HIV-1 receptor molecules, do not support efficient viral gene

81 r rotation; phospho-CheB covalently modifies receptor molecules during sensory adaptation.

82 as subsequently discovered that for the same receptor molecule (e.g., the beta-adrenergic receptor),

83 appears to promote a long-lasting change in receptor molecules, either a covalent modification or co

84 alysis revealed that 30% of the photoexcited receptor molecules followed Cycle 1 through the K, M, O,

85 ombined results indicate that the endogenous receptor molecule for AF/R1 fimbriae of RDEC-1 is each i

86 The proteoglycan biglycan is a receptor molecule for flow-resistant adhesion of the bac

87 stent relationship between the affinity of a receptor molecule for its cognate ligand(s) and the spec

88 dy strengthens the argument that CX3CR1 is a receptor molecule for RSV.

89 study, we identify the tetraspanin CD82 as a receptor molecule for the Galalpha1,3-Gal-independent me

90 ell-restricted expression of CD21, the major receptor molecule for the virus.

91 ntry processes, possibly acting as a primary receptor molecule for this virus.

92 N and L-SIGN may represent common attachment receptor molecules for arthropod-borne viruses, (ii) arb

93 The receptor molecules for human and animal hepatitis B viru

94 s relatively immobile with only 28 +/- 1% of receptor molecules free to diffuse with D = (3.64 +/- 0.

95 Our experiments suggest that the Wnt receptor molecule Frizzled7 probably transduces the Wnt6

96 in receptor (IR) that redirects internalized receptor molecules from endosomes to the plasma membrane

97 for binding but also to depletion of the co-receptor molecules from the cell surface.

98 lation involves the trafficking of activated receptor molecules from the plasma membrane, through cla

99 Additionally, it was found for symmetrical receptor molecules from the same compound family that th

100 ansfer of many types of receptor and counter-receptor molecules from the surface of one conjugated ce

101 ges in relative orientations between the two receptor molecules from the transient complex to the 1ra

102 Hitherto, no receptor molecule has been identified that could account

103 matrices and its interaction with a natural receptor molecule has tremendous importance in cell sign

104 ons, on dynamic covalent libraries (DCLs) of receptor molecules, here ligands for metal cations.

105 Several organelles, receptor molecules, homeostatic processes, and signal tr

106 otif displays a strong binding affinity with receptor molecules (i.e., single-stranded DNA and antibo

107 nt adhesive phage protein has been used as a receptor molecule in biosensing scheme.

108 30 min of insulin treatment, virtually every receptor molecule in this compartment completes at least

109 The conformations of the receptor molecules in all three complexes are very simil

110 is involved in binding to specific host cell receptor molecules in cattle and sheep.

111 n of P. aeruginosa, that it binds to protein receptor molecules in HCEP, that one of the LPS binding

112 in the second intracellular loop of the FMLP receptor molecules in LP patients may play a role in the

113 ion, creates much of the diversity of immune receptor molecules in the adaptive immune system.

114 Individual receptor molecules in the apo form repeatedly sample bot

115 diates an intriguing parallel association of receptor molecules in the crystal lattice.

116 The role of co-receptor molecules in the generation of inducible regula

117 eptor (beta2AR), we observed that individual receptor molecules in the native-like environment of pho

118 band with a ratio of 1:0.9 +/- 0.05 (ligand:receptor molecule) in ligand binding using a Ni column w

119 has the ability to recognize and cleave each receptor molecule independently.

120 ts using chimeric and domain deletion mutant receptor molecules indicate that the amino-terminal D1 d

121 ction of these cytokines with their specific receptor molecules initiates a broad and varied array of

122 The differences among the properties of the receptor molecule interacting with the ligands correlate

123 ) chaperones 11-cis-retinal to convert opsin receptor molecules into photosensitive retinoid pigments

124 y neurons in the spinal cord, and the ligand-receptor molecules involved in cell-to-cell recognition.

125 ient translation of transmembrane domains of receptor molecules involved in cytokine-mediated process

126 Structural studies of cellular receptor molecules involved in immune recognition requir

127 A water-soluble synthetic receptor molecule is capable of selective, controlled en

128 Anion binding by receptor molecules is a central field of modern chemistr

129 d range of antigens, the number of different receptor molecules is extremely large, resulting in a hu

130 e, equal subsites versus binding to separate receptor molecules is given.

131 of the transporter molecules relative to the receptor molecules is not well delineated.

132 and a threshold number of CD4 and chemokine receptor molecules is required to support virus infectio

133 ribution of neurotransmitter transporter and receptor molecules, is a relevant component of structure

134 family of protein tyrosine phosphatase-like receptor molecules (known as IA-2 and PTP-NP/PTP-IAR/IA-

135 A new 1,1'-thiobis(2-naphthoxy)-based receptor molecule (L) containing a benzimidazole moiety

136 d dynamic behavior of DMFM upon binding with receptor molecule molecular docking and dynamic simulati

137 Signalling through the cell-surface receptor molecule Notch may regulate oligodendrocyte dif

138 These studies identify CD8 as a PNA receptor molecule on immature thymocytes and show that P

139 We show that the area per receptor molecule on the cantilever surface influences l

140 velop antivirals directed against either the receptor molecule on the cell or the receptor-binding pr

141 sm determinant), which specifies tropism for receptor molecules on host Bordetella species.

142 ability in a gene that specifies tropism for receptor molecules on host Bordetella species.

143 fully tracked single epidermal growth factor receptor molecules on live cells for up to one hour, rev

144 dral when they initially bind to one or more receptor molecules on the cell surface, such an interact

145 tionalization to form a linker to immobilize receptor molecules on the sensor surface.

146 We immobilized specific receptor molecules on the surface of superparamagnetic b

147 All viruses need to bind to specific receptor molecules on the surface of target cells to ini

148 In cells expressing high numbers of receptor molecules on their surfaces, the SF162-derived

149 rasitic helminths express signal-transducing receptor molecules on their surfaces.

150 Deploying FABP and MPO specific scFvs as receptor molecules onto our high-sensitivity graphene-co

151 e Hedgehog (Hh) signal is transmitted by two receptor molecules, Patched (Ptc) and Smoothened (Smo).

152 Thus, while alpha2M* ligates only one GRP78 receptor molecule per alpha2M*, it may potentially serve

153 erage of approximately 6.2 x 10(5) synthetic receptor molecules per cell surface.

154 ss both a classic multiple membrane-spanning receptor molecule (Pit1) and a second coreceptor or entr

155 Viruses can bind to alternative receptor molecules present on epithelial surfaces and th

156 bition, lantibiotics must recognize specific receptor molecules present on the sensitive bacterial ce

157 on of the HIV envelope with the CD4 and CCR5 receptor molecules present on the surface of target cell

158 Consistent with the idea that soluble receptor molecules provide a trigger for HSV entry, HVEM

159 uirement indicate that the Platynereis light receptor molecule r-Opsin1 serves as a receptor that sen

160 taneously and competitively to two different receptor molecules, R1 and R2.

161 Only about 30% of receptor molecules recycled back to the cell surface in

162 d gene of Drosophila encodes a transmembrane receptor molecule required for cell polarity decisions i

163 role is to accommodate the millions of light receptor molecules required for efficient photon collect

164 The data suggest that two regions of the EGF receptor molecule, residues 1022-1063 and to a lesser ex

165 sent study, we demonstrate that CXCR1 is the receptor molecule responsible for p17 chemokine-like act

166 n vivo blockade of TNF-alpha using a soluble receptor molecule results in accelerated reendothelializ

167 In such a system, each receptor molecule retains a single on-state and off-stat

168 t be essential to orient the toxin to midgut receptor molecule(s).

169 (PDK4), single-immunoglobulin interleukin-1 receptor molecule (SIGIRR), mitochondrially encoded ATP

170 atory stimuli using a complex arrangement of receptor molecules, signaling cascades, and ion channels

171 with some values for previously unpublished receptor molecules, spanning a workflow of 8 years.

172 nformation in which it is bound to three CD4 receptor molecules (state 3)(8-10).

173 ytes to adhere to host endothelial cells via receptor molecules such as ICAM-1 and CD36 is considered

174 utilized to quantitatively detect individual receptor molecules (T-ZZ), map the distribution of recep

175 endoplasmic reticulum (ER) exit sites by the receptor molecule TANGO1/cTAGE5.

176 neurons (ORNs) that express a common odorant receptor molecule target specific glomeruli in the olfac

177 CD122 showed that FLS expressed 4 times more receptor molecules than DF.

178 e CCR5 gene encodes a cell-surface chemokine-receptor molecule that serves as a coreceptor for macrop

179 CCR5 encodes a cell surface chemokine receptor molecule that serves as the principal corecepto

180 e CCR5 gene encodes a cell surface chemokine receptor molecule that serves as the principal corecepto

181 ajor histocompatibility complex (MHC) encode receptor molecules that are responsible for recognition

182 and development of the olfactory system, the receptor molecules that bind odors have not been identif

183 e effectors (TALEs) as the first DNA-binding receptor molecules that provide direct, individual selec

184 pre-Golgi producing highly mobile cytosolic receptor molecules that rapidly accumulate in the nucleu

185 The discovery of these viral substrate receptor molecules that recruit Cul5 through distinct me

186 here we understand some of the signaling and receptor molecules that stimulate and guide cell movemen

187 ship between measures of brain dopamine D(2) receptors (molecules that transmit dopamine signals) and

188 luding increased expression of growth factor receptors, molecules that are involved in tumor invasion

189 Glyco-immune checkpoint receptors, molecules that inhibit immune cell activity f

190 While the L1 acts as a receptor molecule, the L2 acts as a control molecule.

191 , while in cells expressing small numbers of receptor molecules, the mutant viruses replicate with ma

192 a cooperative behavior between near-neighbor receptor molecules; the properties of this cooperative p

193 Nonclassical receptor molecules theoretically could act as a type of

194 in which stimulus information travels within receptor molecules through shifts in the dynamic propert

195 Viruses use specific receptor molecules to bind selectively to target cells.

196 We used chimeric hCCR-5-mCCR-5 receptor molecules to examine the functional importance

197 suggested that one Spz cross-links two Toll receptor molecules to form an activated complex.

198 E has been demonstrated by using soluble TNF-receptor molecules to inhibit EAE.

199 l studies of purified recombinant ligand and receptor molecules to investigate the differences in sig

200 parates the intracellular domains of the two receptor molecules to make room for the associated Janus

201 structures over a scale ranging from single receptor molecules to synapses and neurons.

202 sfolded LRP can be re-folded into functional receptor molecules upon Ca2+ restoration.

203 These results indicate that the complex of receptor molecules used by HTLV-3 to bind to primary T l

204 The presence of an oligomeric complex of CCK receptor molecules was confirmed in co-immunoprecipitati

205 witching mechanism to tune the affinity of a receptor molecule, we first generated a set of receptor

206 arch for genes which encode human interferon receptor molecules, we applied the technique of exon tra

207 Using soluble chimeric receptor molecules, we have demonstrated that meningococ

208 he related CD1a, CD1b, CD1c, and neonatal Fc receptor molecules were absent from the surfaces of beta

209 Only 51.5 +/- 7.8% of receptor molecules were found on the plasma membrane in

210 osslinking indicated that most of the cell's receptor molecules were organized in higher-order groups

211 LDL receptor molecules were visualized as elongated, stick-l

212 actory transduction, finding that an odorant-receptor molecule when (one-time) complexed with its mos

213 While GRKs phosphorylate and inactivate receptor molecules which are engaged in G-protein activa

214 In addition, we constructed chimeric receptor molecules which contain the ligand-binding extr

215 ntial postendocytic processing of ligand and receptor molecules, which impacts long-term cell signali

216 s/ml, suggesting that if there is a specific receptor molecule with which the toxin interacts, it is