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1 s of the conserved AP2/ERF domain in the DNA recognition sequence.
2 owing transient HOXA9 binding to its cognate recognition sequence.
3 ed at two critical positions within the CTCF recognition sequence.
4 target cytosine and frameshifting of the DNA recognition sequence.
5 iption activator capable of binding a unique recognition sequence.
6 e second recognizes the 3' half (CGC) of the recognition sequence.
7 asmic Cu(+) homeostasis and its putative DNA recognition sequence.
8 th rates as a function of the quality of the recognition sequence.
9 osylase) excises unmethylated bases from its recognition sequence.
10 to occur independently of a specific peptide recognition sequence.
11 ransferred to different positions in the RNA recognition sequence.
12 l that also correspond to helix 1 of the LC7 recognition sequence.
13 ffinity as a monomer to a single copy of its recognition sequence.
14 ein dissociates from the DNA or it finds the recognition sequence.
15  FokI (GGATG 9/13) and cleaves closer to the recognition sequence.
16  site and a single monomer covers the entire recognition sequence.
17 A towards the stationary enzyme bound at the recognition sequence.
18  TATA box but not a transcription factor IIB recognition sequence.
19 heir interactions with opposite sides of the recognition sequence.
20 ax6 from binding the consensus paired domain recognition sequence.
21 itinated directly by APC/C(Cdh1) via a novel recognition sequence.
22  displacement of NKX3.1 from its cognate DNA recognition sequence.
23 ater molecules for the last 2 nt in the core recognition sequence.
24 ein and decreased binding to its cognate DNA recognition sequence.
25 econd monomer that remains detached from the recognition sequence.
26 veral complementary miRs harboring the PDE4D recognition sequence.
27 de substrate that mimics the PLpro replicase recognition sequence.
28 hen transferred to an adenine within the DNA recognition sequence.
29 ion of the protein to the binding of its DNA recognition sequence.
30 rs even when the DNA does not contain an ETS recognition sequence.
31 l share a common motif that matches the YBX1 recognition sequence.
32 plex with double-stranded DNA containing the recognition sequence.
33 f the reporter by reengineering the protease recognition sequence.
34 ry code specifying transcription factor (TF) recognition sequences.
35 se genes are active but also revealing their recognition sequences.
36 sm were sub-cloned to test for viability and recognition sequences.
37 ias 24% of integrations near endogenous Gal4 recognition sequences.
38 mbining gene segments and their flanking RAG recognition sequences.
39 d between leading and trailing 12-nucleobase recognition sequences.
40  of motifs, corresponding to Hox and Pbx-Hox recognition sequences.
41 display limited diversity in their preferred recognition sequences.
42 y selective natural and unnatural amino acid recognition sequences.
43 ect repeats, which presumably contain kinase recognition sequences.
44 gma(E) dependent based on consensus promoter recognition sequences.
45 heir aligned amino-acid residues and aligned recognition sequences.
46 re length of coding regions only at specific recognition sequences.
47 WM motif to also inhibit binding to Hox-only recognition sequences.
48 P49 and P35 also differ in their RSL caspase recognition sequences.
49 alpha gene promoter that served as the NFAT3 recognition sequences.
50 exhibit the largest variation from consensus recognition sequences.
51 exes of lambda Cro repressor with varied DNA recognition sequences.
52 ition sequences, CBF promoters also have Myb recognition sequences.
53  its inability to bind cognate paired domain recognition sequences.
54 A elements bearing marked similarity to STAT recognition sequences.
55 tic reactions, paradoxically involving short recognition sequences.
56  types through evolutionary innovation of TF recognition sequences.
57 o bind to probes containing the putative IHF recognition sequences.
58 ily with regards to the composition of their recognition sequences.
59  genes, and methylome analysis reveals their recognition sequences.
60 or two sortase A enzymes that have different recognition sequences.
61 hosphodiester linkage in the pentapyrimidine recognition sequence 5'-(C/T)+5 C+4 C+3 T+2 T+1 p / N(-1
62 hosphodiester linkage in the pentapyrimidine recognition sequence 5'-(C/T)+5C4+C3+T+2T+1p \N-1 using
63 combination with the bases flanking the core recognition sequence 5'-CGY M6A: G-3'.
64 loop translocation rightward of the specific recognition sequence 5'-CTnGAyG-3' as written (where n i
65  seen with the Escherichia coli DnaG primase recognition sequence 5'-d(CTG)-3'.
66 -7 nucleotides) downstream of the asymmetric recognition sequence 5'-GCCGC-3'.
67        NotI from Nocardia otitidis-caviarum (recognition sequence 5'-GCGGCCGC-3') has been cloned, th
68                                     The NarI recognition sequence (5'-G1G2CG3CN-3') is the most vulne
69 ificity at four of the six base pairs of the recognition sequence (5'-TCCRAC-3').
70 ificity changes at the first position of the recognition sequence (5'-TCCRAC-3').
71 gher affinity for DNA containing the primase recognition sequence (5'-TGGTC-3') than for DNA lacking
72           Complexes formed by five different recognition sequences (5'-GGCCNNNNNGGCC-3'), with differ
73 rent forms of modified cytosine within their recognition sequence, 5'-GCG(T/G)GGGCG-3'.
74 article discusses an unusually short protein recognition sequence, 5'CG, which is read by multiple DN
75 al potential substrates contained the IPTase recognition sequence A36A37A38 in the anticodon loop, on
76         The nuclear myosin II is tethered to recognition sequence AGCTCC (-39/-34) in the intercellul
77  suggest that RRM interactions with specific recognition sequences alone do not account for nucleatin
78 e should happen specifically at the enzyme's recognition sequence, an unknown proportion of cleavage
79 e human enzyme to recognize part of the core recognition sequence and activate the enzyme for catalys
80 mutational analysis of RCC1 defined the NRMT recognition sequence and enabled the identification of n
81 ion endonuclease that cuts an unusually long recognition sequence and exhibits allosteric self-modula
82 a-673 residue lies within the beta-secretase recognition sequence and is part of the amyloid-beta (Ab
83 e results define the SigB promoter consensus recognition sequence and members of the SigB regulon.
84              MmeI cuts DNA 20 bases from its recognition sequence and modifies just one DNA strand fo
85 ic Bcl2 family protein, which have the KXTQT recognition sequence and neuronal nitric oxide synthase
86                               Nos shifts the recognition sequence and promotes repression complex for
87 ) that methylates a specific base within the recognition sequence and protects DNA from cleavage by t
88  now show that this threshold depends on the recognition sequence and scales linearly with the dissoc
89 ified using a nicking endonuclease with 7-bp recognition sequence and Sequenase version 2.0 in the pr
90            Codon selection, releasing factor recognition sequence and specific introns and 3' untrans
91 ing binding specificity outside the core GGA recognition sequence and the mode of action of Ets post-
92  induce DNA double-strand breaks at specific recognition sequences and can promote efficient introduc
93 folds that include Ag(+)-ions or Hg(2+)-ions recognition sequences and the replication tracks that yi
94 tative cargo, Swallow, which share the KXTQT recognition sequence, and addresses the apparent paradox
95 ction endonucleases cleave DNA outside their recognition sequences, and are therefore particularly us
96 The method involves the conjugation of a DNA recognition sequence (aptamer) to the catalytic DNAzyme,
97 ng virulence factors, that have a C terminal recognition sequence are attached to Gly5 on the peptido
98  MmeI and delineates which base pairs of the recognition sequence are more amenable to alterations th
99                                 Although DNA-recognition sequences are among the most important chara
100 one within nuclear factor-kappaB (NF-kappaB) recognition sequences are identical, homodimers of c-Rel
101 d that functional mammalian microRNA (miRNA) recognition sequences are located preferentially in the
102 lained partially by the presence of fewer GR recognition sequences, arguing for the existence of addi
103 pin B8 demonstrated that both the P4-P1 RXXR recognition sequence as well as the P1'-P5' sequence are
104       The PAX5 fusion products bound to PAX5 recognition sequences as strongly as wild-type PAX5 and
105 B. burgdorferi, nor are any sigma28 promoter recognition sequences associated with the motility genes
106 al selectivities dominated by the respective recognition sequences associated with the scaffolds.
107 ytic site enabling this enzyme to cleave the recognition sequence at a different position.
108  though simple, requires that nicking enzyme recognition sequence be present in the target DNA.
109 ding FokI, interact with two copies of their recognition sequence before cutting DNA.
110 rent specificity groups, where the preferred recognition sequence between these groups can differ at
111 vels of the transcription factor recombinant recognition sequence binding protein at Jkappa site (RBP
112 ow that the transcription factor recombinant recognition sequence binding protein at the J(kappa) sit
113 aled that ET increased levels of recombinant recognition sequence binding protein at the Jkappa site
114 utant triggered up-regulation of recombinant recognition sequence-binding protein at the Jkappa site
115 ly increases the length and diversity of DNA-recognition sequence by reusing DBDs from the same famil
116 nd CLOCK suppressed binding of GR to its DNA recognition sequences by acetylating multiple lysine res
117 e human papillomavirus by immobilizing short recognition sequences by amidation or thiol-maleimide re
118 of plasmid DNA, designed to contain the MerR recognition sequence, by a simple temperature trigger.
119 ion of a coumarin fluorophore onto a peptide recognition sequence called LAP1.
120   Recent evidence identified a novel AhR DNA recognition sequence called the nonconsensus xenobiotic
121 r longer target strands, the position of the recognition sequence can be designed in a way that a sma
122  show that specific residues in the protease recognition sequence can differentially modulate the eff
123  high false positive rates; functional miRNA recognition sequences can be as short as six nucleotides
124          A nondegradable Iqg1p (lacking this recognition sequence) can suppress the myo1Delta phenoty
125                               Apart from Myc recognition sequences, CBF promoters also have Myb recog
126 was shown to specifically bind its consensus recognition sequence (CGGGTAA, -166 to -160) in the DGK1
127 ximal activity on DNA with two copies of its recognition sequence, cleaving both sites concertedly.
128 the flgE or napA promoter and includes a Fur recognition sequence common to the H. pylori pfr and sod
129 fected with an Ebola virus lacking the furin recognition sequence compared to those infected with wil
130 nscription factors, Pdx1 binds to a core DNA recognition sequence containing the tetranucleotide 5'-T
131                                     The BcgI recognition sequence contains one adenine in each strand
132 r how the interaction of gamma with specific recognition sequences coordinates directional DNA transl
133 he two forms of p53 bound to a consensus DNA recognition sequence could not be distinguished and were
134 ligomers by Watson-Crick base pairing of the recognition sequences creates linear or cyclic arrays of
135 he substitutions and a polypeptide consensus recognition sequence deduced from the results.
136 vates Thioflavin T fluorescence and a target recognition sequence designed to interact in a molecular
137 eation peptide sequence, an effector caspase recognition sequence, DEVD, and a flanking optically act
138 active site is positioned initially near the recognition sequence, distant from its downstream target
139                            Matalpha1 and its recognition sequence diverged most dramatically in the c
140 insertion of 31 amino acids in the caspase-3 recognition sequence DMQD.
141 NA tail might form upon encounter of a "Chi" recognition sequence during unwinding of DNA by the RecB
142 re separate constructs with their own unique recognition sequences, ERT2-GAL4 is compatible with the
143                                              Recognition sequences exhibit a periodic purine-pyrimidi
144 nylation assay, peptide probe 3 with a RLRGG recognition sequence exhibited the highest activity, wit
145 incubations with recombinant phosphotyrosine-recognition sequences expressed as GST-fusion proteins.
146 -based reporter was designed to contain a LF recognition sequence flanked by the FRET pair formed by
147 enzymes at two distant, inversely orientated recognition sequences followed by helicase-catalysed ATP
148 ion, asparagine (N) in the canonical N-X-S/T recognition sequence for carbohydrate attachment was cha
149 t adjacent ends of a linker that encoded the recognition sequence for caspase-3.
150                                The consensus recognition sequence for GSK3 (Ser(76)/Ser(80)) is evolu
151  domain, we first investigated the preferred recognition sequence for TBX22.
152 he circular nucleic acid template includes a recognition sequence for the analyte DNA (the Tay-Sachs
153 in promoter CACCC site, indicating a broader recognition sequence for the EKLF consensus binding site
154 ey are enriched in TAATTA, which is also the recognition sequence for the homeodomain DNA-binding mod
155 e algorithm enumerates all possible extended recognition sequences for 16S rRNA and then chooses thos
156   Our data reveal unanticipated diversity in recognition sequences for chaperones; establish a sequen
157 rates for each protease created by appending recognition sequences for ClpCP or ClpXP to the green fl
158  sequence more strongly than to the usual AT recognition sequences for curved minor groove agents.
159 encodes an expansive repertoire of conserved recognition sequences for DNA-binding proteins that near
160 ognition domain (CRD) as well as LDV and RGD recognition sequences for integrin binding.
161                        Specifically, epitope recognition sequences for the 2F5, 4E10, and 447-52D ant
162  systematically perturb transcription factor recognition sequences, frequently alter allelic chromati
163 id reporter that included predicted miR-196a recognition sequence from ANXA1 3'-untranslated region c
164              NusG protects T residues of the recognition sequence from permanganate oxidation, and th
165 nosine and cytidine residues within the HhaI recognition sequence GCGC experience motions on a much s
166 rs of the five genes conform to the proposed recognition sequence GNCCN9GGNG, where N is any nucleoti
167 ts both sites upstream and downstream of the recognition sequence, hydrolyzing eight phosphodiester b
168 U0126 decreased NF-kappaB binding to its DNA recognition sequence, implicating the MAPK pathway in NF
169                  The binding of EcoR1 to the recognition sequence in DNA appears as a rapid increase
170 stin-like polypeptide (ELP) fused to a short recognition sequence in E. coli, we show robust and high
171  of at least one physiological miR-107 miRNA recognition sequence in the 3'-UTR of BACE1 mRNA.
172     The IDOL FERM domain binds directly to a recognition sequence in the cytoplasmic tails of lipopro
173                      We identified an NKX6.1 recognition sequence in the distal region of the HNF1alp
174 eover, we identified an Akt/protein kinase B recognition sequence in the PML-binding domain of MOZ pr
175 f mice (MVM) first binds to a simple cognate recognition sequence in the viral origins, comprising tw
176  pTypeI, which contains all of the 27 Type-I recognition sequences in a 248-bp DNA fragment.
177                    Variants with 2F5 or 4E10 recognition sequences in gp41 retained replication compe
178 ing regions and perturb transcription factor recognition sequences in relevant cell types.
179 t motifs (PAMs) that restrict the density of recognition sequences in target DNA.
180                        ICE1 binds to the Myc recognition sequences in the CBF3 promoter.
181 onstant for the binding of active FNR to its recognition sequences in the DNA.
182          Tailup was shown to bind to two DNA recognition sequences in the dorsal vessel enhancer of t
183  represent only a small minority of the CTCF recognition sequences in the human genome.
184 protein interacts with ICE1 and binds to Myb recognition sequences in the promoters of CBF genes.
185 NA is the paucity of structural data for DNA recognition sequences in their free (unbound) state.
186 d T3 enzymes, elements in or near the enzyme recognition sequence influenced their activity and requi
187 rs independently of DNA binding at NF-kappaB recognition sequences, instead binding with SMAD family
188                         An artificial I-SceI recognition sequence integrated into genomic DNA was ana
189                  By incorporating additional recognition sequences into the DNA linkers, defined hete
190                  Transfer of the TMV Pumilio recognition sequences into the genome of potato virus X
191            Further, we find that the Gas5 SR-recognition sequence is conserved among haplorhines, wit
192 t that the specificity of HscA for the LPPVK recognition sequence is determined in part by steric obs
193 ambda-development in vivo and a specific IHF recognition sequence is found within cos.
194                            An HIV-1 protease recognition sequence is inserted into one of the surface
195                               Since the THAP recognition sequence is short, and will occur many times
196 s referred to as the AP2 domains and its DNA recognition sequence is still unknown.
197 he assembly of DnaA complexes at chromosomal recognition sequences is affected by the tight binding o
198  possessing the complete Survivin and INCENP recognition sequence, is required for the composition of
199 nd that to cleave a DNA with one copy of its recognition sequence, it has to act in trans, bridging t
200 o cellular proteins fused to a 13-amino acid recognition sequence (LAP), catalyzed by a mutant of the
201  new general method for the determination of recognition sequences longer than three bases for mRNA i
202  considerably from that of its bacteriophage recognition sequence, loxP.
203 bstrates bearing a five amino acid sortase A recognition sequence (LPETG).
204                                  The sortase recognition sequence, LPXTG (for Streptococcus aureus so
205 genes does not resemble a sigma 70 consensus recognition sequence; moreover, it is upstream of two ge
206 athic helix, without requiring a cholesterol recognition sequence motif.
207 th three different C-terminal target protein recognition sequence motifs by CD, fluorescence, and hig
208 es, computational approaches based on kinase recognition sequence (motifs) from known substrates, pro
209 ntroduction of the methylation site into the recognition sequence of a restriction endonuclease, and
210 rresponding methylases, determination of the recognition sequence of a Type-I restriction enzyme is a
211 DNA at specific sites in the vicinity of the recognition sequence of C.BclI.
212 t codons that closely resemble the consensus recognition sequence of Escherichia coli integration hos
213                       Here, we determine the recognition sequence of LlaBIII (5'-TnAGCC-3', where the
214 ide, pKID-Abl, was designed to incorporate a recognition sequence of the Abl kinase.
215 1 and other mycotoxins by replacing the core recognition sequence of the aptamer.
216 hibitor that triggers cleavage of the target-recognition sequence of the Cas12a-bound guide RNA to ir
217  and C-X3-C contexts in the C-G1-G2-C-G3-C-C recognition sequence of the NarI restriction enzyme were
218 '-CTCG(1)G(2)CG(3)CCATC-3' that contains the recognition sequence of the NarI Type II restriction end
219 at variability results in alterations to the recognition sequence of this R-M system.
220 PROTACS is a novel approach of tagging small recognition sequences of a specific E3 ubiquitin ligase
221 nd with the advent of PacBio sequencing, the recognition sequences of DNA methyltransferases (MTases)
222                                 The splicing recognition sequences of exon 3 are less favorable than
223                                  Because the recognition sequences of miRNAs for their targets are sh
224  one either side of the site, to release the recognition sequence on a short DNA fragment; 34 bp long
225                                      The LC7 recognition sequence on IC and its interface with LC7 ar
226 uence partially overlaps the light chain LC7 recognition sequence on IC, raising questions about the
227 rget a region upstream of the FIP/BIP primer recognition sequences on opposite strands, substantially
228 cal data, a model of ComAC bound to the ComA recognition sequences on the srfA promoter has been deve
229 e-strand breaks (DSBs) at each copy of their recognition sequence, one either side of the site, to ex
230 lized to two variants of the canonical KIN10 recognition sequence, one in each of its two AP2 DNA bin
231 st of the genes identified have specific AHR recognition sequences, only seven genes were altered exc
232 led with the ability to introduce a CAAX-box recognition sequence onto almost any protein, this metho
233                                 No consensus recognition sequence or structure has been identified fo
234 f proteins and/or noncoding RNAs to specific recognition sequences or secondary structures within mRN
235                                      The FGE recognition sequence, or aldehyde tag, can be inserted i
236        Here we show that Ste5 and Ste20 have recognition sequences, or "docking" sites, for the G1/S
237  Numerous peptide ligands including protease recognition sequences, peptides mediating protein-protei
238 dation of the influence of target length and recognition sequence position on the sensorial performan
239 anyang (NY) cattle, which are located in the recognition sequences (potential cis-acting elements) of
240 hat cleavage takes place outside the (5)mCpG recognition sequence, predominantly 4-17 bp upstream of
241 purified Nanog-Sox2 complex identified a DNA recognition sequence present in multiple overlapping Nan
242 age targets contain a proline-rich consensus recognition sequence, Pro-Pro-Ser-Pro, residing in the v
243         One of the important elements of the recognition sequence, pTyr-Xxx-Xxx-Gln, is glutamine.
244                The diversity of recovered HD recognition sequences raises important questions about t
245 ed HpaII sequences (Cm5CGG), but its precise recognition sequence remains undefined.
246 GTACNTNNNY) was significantly different from recognition sequences reported for Topo IIA from other o
247 cal modification of PS A1 does not alter the recognition sequence responsible for an MHCII-mediated,
248 a series of truncations, we define a minimum recognition sequence (RS) that is necessary and sufficie
249 y requires both clefts to be filled with its recognition sequence: SfiI has low activity when bound t
250 two conserved prolines of the PXXP consensus recognition sequence show more absorptions than there ar
251 endency, with peptide probe 4 with an LRLRGG recognition sequence showed the fastest rate ( t 1/2 = 0
252                            A putative mTORC1-recognition sequence sits within a flexible loop C-termi
253 haracterization of siRNA binding, target RNA recognition, sequence-specific cleavage and product rele
254                     Mutations within the Sp1 recognition sequence specifically eliminated binding of
255 inds to an imperfect direct repeat COUP-TFII recognition sequence (termed hereafter proxDR) in the pr
256 igh affinity to a broader range of NF-kappaB recognition sequences than did wild-type p65 homodimers.
257           We show that mutations in the Elba recognition sequence that eliminate Elba binding in nucl
258 ll adhesion tripeptide motif, is an integrin recognition sequence that facilitates PET imaging of int
259  a picolyl azide (pAz) derivative to a 13-aa recognition sequence that has been genetically fused ont
260 inJ dimer at a single inverted repeat of its recognition sequence that overlaps with the -10 promoter
261 fluorogenic DNA-binding dye to the caspase-3 recognition sequence that renders the dye nonfunctional.
262  induced by the mutation(s) unmasked a furin recognition sequence that was used for cleavage.
263 ely regulate Rv0081 expression by binding to recognition sequences that either partially or completel
264 rocessivity for facilitating encounters with recognition sequences that modify enzyme function during
265 -glutamate-serine-threonine-rich proteolytic recognition sequence, the absence of which has previousl
266  ability to bind the consensus paired domain recognition sequence; the others were unable or only par
267 fine their orientation and register on their recognition sequences, thereby allowing us to define the
268  recognition at three positions within their recognition sequences through correlations between their
269 unctions (HJs) that contain specific protein-recognition sequences to report protein-DNA interactions
270 es together, their binding to the respective recognition sequences triggers the nicking/polymerizatio
271 NA structures with higher affinity than TraB-recognition sequences (TRSs).
272   The resulting MazF-bs(can) gained a 6-base recognition sequence, UACAUA, for RNA cleavage instead o
273 one of these trinucleotides were known to be recognition sequences used by other microbial primases.
274 ptin and the removal of the calpain-cleavage recognition sequence, via site-directed mutagenesis, abo
275                  The SigG consensus promoter recognition sequence was identified as GCGNGT-N15-18-CGA
276                                An asymmetric recognition sequence was identified, 5'-CTnGAyG-3' (wher
277  target genes regulated by EcfO, and an EcfO recognition sequence was identified.
278 erase-encoding gene (hpt) was flanked by ZFN recognition sequences was constructed.
279 FP) coding sequence (gfp) was flanked by ZFN recognition sequences was used to produce transgenic tar
280            In contrast to canonical protease recognition sequences, we show that IsdG is targeted for
281 ks and flanking 5'- and 3'-single-strand DNA recognition sequences were combined in buffer solution.
282 l methylation patterns corresponding to nine recognition sequences were detected (26695, 3; J99-R3, 6
283  plasmids'), each containing a unique Type-I recognition sequence, were also constructed using pMECA,
284        Each McbB dimer clamps the N-terminal recognition sequence, while the C-terminal heterocycle o
285  methyltransferase flips the second C in the recognition sequence, while the endonuclease flips both
286 s an engineered mutation in the conserved PC recognition sequence, while the PC furin cleaves 50 kDa
287 plementarily to the middle nucleotide of the recognition sequence, while the third nucleotide, an ade
288  required sub-cloning to differentiate their recognition sequences, while four MTase genes that were
289 ubstantially faster than the canonical DDDDK recognition sequence, widely used for protein purificati
290                         TFs target their DNA-recognition sequences with high specificity by binding w
291 ed oligonucleotide containing the target DNA recognition sequence, with a methylene blue tag close to
292                   The Elba factor binds to a recognition sequence within a Fab-7 subelement that has
293 F binding and dissociation dynamics at their recognition sequence within duplex DNA, single nucleosom
294 ned rapidly by simply replacing the enzyme's recognition sequence within the generic labeled molecule
295                We identified consensus Egr-1 recognition sequences within proximal and distal regions
296 tion site and that mutation of the consensus recognition sequences within these sites ablated their t
297 Areas I and II, despite the absence of Egr-1 recognition sequences within this promoter segment, sugg
298 gether with the presence of caspase cleavage recognition sequences within virally encoded proteins, w
299 was possible to match MTase genes with MTase recognition sequences without further sub-cloning.
300        These DNA modules were encoded so the recognition sequences would uniquely associate through W

 
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